ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
EPKFIKFJ_00001 8.39e-316 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPKFIKFJ_00002 2.83e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPKFIKFJ_00003 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
EPKFIKFJ_00004 1.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPKFIKFJ_00005 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
EPKFIKFJ_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPKFIKFJ_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPKFIKFJ_00008 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00011 1.64e-224 yaaC - - S - - - YaaC-like Protein
EPKFIKFJ_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EPKFIKFJ_00013 1.03e-315 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPKFIKFJ_00014 7.47e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EPKFIKFJ_00015 2.35e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EPKFIKFJ_00016 4.16e-281 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPKFIKFJ_00017 2.36e-251 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
EPKFIKFJ_00019 1.4e-154 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
EPKFIKFJ_00020 3.32e-148 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
EPKFIKFJ_00021 8.84e-272 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
EPKFIKFJ_00022 4.62e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
EPKFIKFJ_00023 5.61e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPKFIKFJ_00024 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPKFIKFJ_00025 6.9e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPKFIKFJ_00026 6e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPKFIKFJ_00027 7.67e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
EPKFIKFJ_00028 2.16e-48 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
EPKFIKFJ_00029 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00032 3.55e-39 csfB - - S - - - Inhibitor of sigma-G Gin
EPKFIKFJ_00033 1.05e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
EPKFIKFJ_00034 6.32e-226 yaaN - - P - - - Belongs to the TelA family
EPKFIKFJ_00035 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
EPKFIKFJ_00036 7.14e-141 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPKFIKFJ_00037 4.14e-72 yaaQ - - S - - - protein conserved in bacteria
EPKFIKFJ_00038 2.86e-92 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
EPKFIKFJ_00039 8.67e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
EPKFIKFJ_00040 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
EPKFIKFJ_00041 2.53e-55 yabA - - L - - - Involved in initiation control of chromosome replication
EPKFIKFJ_00042 3.28e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
EPKFIKFJ_00043 1.64e-62 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
EPKFIKFJ_00044 9.82e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPKFIKFJ_00045 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
EPKFIKFJ_00046 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPKFIKFJ_00047 1.44e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
EPKFIKFJ_00048 3.55e-288 yabE - - T - - - protein conserved in bacteria
EPKFIKFJ_00049 3.1e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EPKFIKFJ_00050 9.41e-200 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPKFIKFJ_00051 1.46e-186 yabG - - S ko:K06436 - ko00000 peptidase
EPKFIKFJ_00052 5.32e-53 veg - - S - - - protein conserved in bacteria
EPKFIKFJ_00053 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
EPKFIKFJ_00054 2.25e-205 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPKFIKFJ_00055 5.43e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
EPKFIKFJ_00056 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
EPKFIKFJ_00057 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
EPKFIKFJ_00058 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPKFIKFJ_00059 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPKFIKFJ_00060 1.4e-133 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EPKFIKFJ_00061 4.99e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPKFIKFJ_00062 5.24e-53 yabK - - S - - - Peptide ABC transporter permease
EPKFIKFJ_00063 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPKFIKFJ_00064 1.09e-116 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
EPKFIKFJ_00065 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKFIKFJ_00066 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
EPKFIKFJ_00067 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EPKFIKFJ_00068 5.47e-66 yabP - - S - - - Sporulation protein YabP
EPKFIKFJ_00069 1.47e-128 yabQ - - S - - - spore cortex biosynthesis protein
EPKFIKFJ_00070 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
EPKFIKFJ_00071 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EPKFIKFJ_00074 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
EPKFIKFJ_00075 8.92e-165 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EPKFIKFJ_00076 1.18e-229 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
EPKFIKFJ_00077 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPKFIKFJ_00078 4.29e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
EPKFIKFJ_00079 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPKFIKFJ_00080 5.46e-186 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EPKFIKFJ_00081 7.52e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPKFIKFJ_00082 1.22e-192 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
EPKFIKFJ_00083 1.79e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EPKFIKFJ_00084 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPKFIKFJ_00085 5.14e-137 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
EPKFIKFJ_00086 3.18e-191 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
EPKFIKFJ_00087 1.62e-196 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EPKFIKFJ_00088 1.88e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPKFIKFJ_00089 4.38e-113 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EPKFIKFJ_00090 9.99e-39 yazB - - K - - - transcriptional
EPKFIKFJ_00091 8.33e-230 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPKFIKFJ_00092 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
EPKFIKFJ_00093 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00103 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00104 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
EPKFIKFJ_00105 8.58e-79 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
EPKFIKFJ_00106 3.84e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
EPKFIKFJ_00107 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
EPKFIKFJ_00108 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPKFIKFJ_00109 1.22e-247 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
EPKFIKFJ_00110 1.85e-245 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
EPKFIKFJ_00111 1.61e-156 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EPKFIKFJ_00112 1.23e-110 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EPKFIKFJ_00113 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPKFIKFJ_00114 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
EPKFIKFJ_00115 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
EPKFIKFJ_00116 9.32e-92 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EPKFIKFJ_00117 9.69e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPKFIKFJ_00118 1.92e-113 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
EPKFIKFJ_00119 4.65e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
EPKFIKFJ_00120 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPKFIKFJ_00121 6.9e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
EPKFIKFJ_00122 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPKFIKFJ_00123 2.04e-159 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPKFIKFJ_00124 6.68e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPKFIKFJ_00125 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPKFIKFJ_00126 2.53e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
EPKFIKFJ_00127 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPKFIKFJ_00128 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPKFIKFJ_00129 9.87e-45 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
EPKFIKFJ_00130 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPKFIKFJ_00131 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPKFIKFJ_00132 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPKFIKFJ_00133 9.55e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPKFIKFJ_00134 3.62e-220 ybaC - - S - - - Alpha/beta hydrolase family
EPKFIKFJ_00135 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
EPKFIKFJ_00136 1.02e-143 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPKFIKFJ_00137 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
EPKFIKFJ_00138 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPKFIKFJ_00139 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPKFIKFJ_00140 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPKFIKFJ_00141 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPKFIKFJ_00142 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPKFIKFJ_00143 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPKFIKFJ_00144 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
EPKFIKFJ_00145 1.92e-51 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPKFIKFJ_00146 1.04e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPKFIKFJ_00147 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPKFIKFJ_00148 2.58e-120 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPKFIKFJ_00149 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPKFIKFJ_00150 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPKFIKFJ_00151 1.05e-119 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPKFIKFJ_00152 2.38e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPKFIKFJ_00153 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPKFIKFJ_00154 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
EPKFIKFJ_00155 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EPKFIKFJ_00156 1.82e-294 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPKFIKFJ_00157 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPKFIKFJ_00158 3.16e-180 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EPKFIKFJ_00159 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPKFIKFJ_00160 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
EPKFIKFJ_00161 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPKFIKFJ_00162 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPKFIKFJ_00163 9.96e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPKFIKFJ_00164 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
EPKFIKFJ_00165 6.9e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPKFIKFJ_00166 1.06e-184 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPKFIKFJ_00167 8.86e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPKFIKFJ_00168 3.42e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPKFIKFJ_00169 3.79e-101 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPKFIKFJ_00170 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
EPKFIKFJ_00171 4.46e-179 ybaJ - - Q - - - Methyltransferase domain
EPKFIKFJ_00173 2.28e-99 ybaK - - S - - - Protein of unknown function (DUF2521)
EPKFIKFJ_00174 4.3e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_00175 4.58e-247 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EPKFIKFJ_00176 1.95e-102 gerD - - - ko:K06294 - ko00000 -
EPKFIKFJ_00177 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
EPKFIKFJ_00178 1.09e-174 pdaB - - G - - - Polysaccharide deacetylase
EPKFIKFJ_00179 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00185 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00186 7.62e-271 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
EPKFIKFJ_00187 1.22e-311 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPKFIKFJ_00188 1.75e-227 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
EPKFIKFJ_00189 1.33e-254 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EPKFIKFJ_00190 7.16e-284 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EPKFIKFJ_00191 1.35e-216 ybaS - - S - - - Na -dependent transporter
EPKFIKFJ_00192 4.92e-130 ybbA - - S ko:K07017 - ko00000 Putative esterase
EPKFIKFJ_00193 9.92e-223 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_00194 1.48e-224 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_00195 1.12e-215 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
EPKFIKFJ_00196 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
EPKFIKFJ_00197 4.44e-291 ybbC - - S - - - protein conserved in bacteria
EPKFIKFJ_00198 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
EPKFIKFJ_00199 6.18e-300 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
EPKFIKFJ_00200 2.44e-302 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_00201 5.23e-205 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EPKFIKFJ_00202 1.13e-76 ybbJ - - J - - - acetyltransferase
EPKFIKFJ_00203 5.95e-96 ybbK - - S - - - Protein of unknown function (DUF523)
EPKFIKFJ_00209 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKFIKFJ_00210 1.7e-146 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
EPKFIKFJ_00211 3.01e-186 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPKFIKFJ_00212 1.1e-291 ybbR - - S - - - protein conserved in bacteria
EPKFIKFJ_00213 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPKFIKFJ_00214 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPKFIKFJ_00215 1.17e-21 - - - S - - - peptidyl-tyrosine sulfation
EPKFIKFJ_00216 2.6e-220 - - - O - - - growth
EPKFIKFJ_00217 5.91e-68 - - - S - - - ABC-2 family transporter protein
EPKFIKFJ_00218 3.47e-126 ybdN - - - - - - -
EPKFIKFJ_00219 9.57e-165 ybdO - - S - - - Domain of unknown function (DUF4885)
EPKFIKFJ_00220 2.34e-203 dkgB - - S - - - Aldo/keto reductase family
EPKFIKFJ_00221 3.49e-134 yxaC - - M - - - effector of murein hydrolase
EPKFIKFJ_00222 6.65e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
EPKFIKFJ_00223 1.27e-89 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_00224 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKFIKFJ_00225 1.67e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
EPKFIKFJ_00226 6.05e-227 - - - T - - - COG4585 Signal transduction histidine kinase
EPKFIKFJ_00227 1.58e-129 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
EPKFIKFJ_00228 2.13e-205 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EPKFIKFJ_00229 1.12e-240 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EPKFIKFJ_00230 7.69e-229 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
EPKFIKFJ_00231 6.5e-33 - - - - - - - -
EPKFIKFJ_00232 1.31e-99 - - - S - - - Domain of unknown function (DUF4879)
EPKFIKFJ_00233 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
EPKFIKFJ_00234 2.99e-136 yqeB - - - - - - -
EPKFIKFJ_00235 2.17e-52 ybyB - - - - - - -
EPKFIKFJ_00236 0.0 ybeC - - E - - - amino acid
EPKFIKFJ_00237 1.8e-22 - - - S - - - Protein of unknown function (DUF2651)
EPKFIKFJ_00238 2.63e-209 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
EPKFIKFJ_00239 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
EPKFIKFJ_00240 1e-23 - - - S - - - Protein of unknown function (DUF2651)
EPKFIKFJ_00241 1.12e-261 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
EPKFIKFJ_00243 1.14e-105 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_00244 5.91e-239 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
EPKFIKFJ_00245 8.16e-265 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPKFIKFJ_00246 9.04e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPKFIKFJ_00247 3.37e-110 ybfM - - S - - - SNARE associated Golgi protein
EPKFIKFJ_00248 4.85e-191 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
EPKFIKFJ_00249 9.76e-52 ybfN - - - - - - -
EPKFIKFJ_00250 4.36e-240 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
EPKFIKFJ_00251 2.61e-266 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKFIKFJ_00252 5.77e-246 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EPKFIKFJ_00253 7.12e-303 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKFIKFJ_00254 4.63e-225 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
EPKFIKFJ_00255 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EPKFIKFJ_00256 7.21e-90 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EPKFIKFJ_00257 4.31e-44 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EPKFIKFJ_00258 2.63e-264 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_00259 2.43e-197 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
EPKFIKFJ_00260 2.31e-158 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
EPKFIKFJ_00261 3.3e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
EPKFIKFJ_00262 8.64e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPKFIKFJ_00263 3.53e-118 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
EPKFIKFJ_00264 5.44e-229 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EPKFIKFJ_00265 1.89e-82 ydfP - - S ko:K15977 - ko00000 DoxX
EPKFIKFJ_00266 3.11e-73 ydfQ - - CO - - - Thioredoxin
EPKFIKFJ_00267 4.68e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
EPKFIKFJ_00268 5.22e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
EPKFIKFJ_00269 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
EPKFIKFJ_00270 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EPKFIKFJ_00271 1.44e-155 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPKFIKFJ_00272 1.99e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EPKFIKFJ_00273 3.41e-241 ycbU - - E - - - Selenocysteine lyase
EPKFIKFJ_00274 1.47e-305 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
EPKFIKFJ_00275 3.35e-125 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EPKFIKFJ_00276 1.19e-58 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EPKFIKFJ_00277 5.9e-21 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
EPKFIKFJ_00278 1.21e-245 yccF - - K ko:K07039 - ko00000 SEC-C motif
EPKFIKFJ_00279 6.43e-211 yccK - - C - - - Aldo keto reductase
EPKFIKFJ_00280 1.13e-210 ycdA - - S - - - Domain of unknown function (DUF5105)
EPKFIKFJ_00281 4.33e-301 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKFIKFJ_00282 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKFIKFJ_00283 1.31e-114 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EPKFIKFJ_00284 3.74e-221 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
EPKFIKFJ_00285 6.52e-174 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
EPKFIKFJ_00286 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EPKFIKFJ_00287 1.5e-62 - - - S - - - Domain of unknown function (DUF4188)
EPKFIKFJ_00288 1.86e-62 - - - K - - - Virulence activator alpha C-term
EPKFIKFJ_00289 5.72e-214 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
EPKFIKFJ_00290 1.15e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
EPKFIKFJ_00291 1.38e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
EPKFIKFJ_00292 8.68e-231 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKFIKFJ_00293 9.56e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
EPKFIKFJ_00294 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EPKFIKFJ_00295 3.36e-136 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
EPKFIKFJ_00296 4.28e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
EPKFIKFJ_00297 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
EPKFIKFJ_00298 1.36e-245 yceH - - P - - - Belongs to the TelA family
EPKFIKFJ_00299 2.43e-265 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
EPKFIKFJ_00301 8.61e-291 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
EPKFIKFJ_00302 2.01e-184 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EPKFIKFJ_00303 4.54e-207 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
EPKFIKFJ_00304 6.41e-261 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
EPKFIKFJ_00305 9.46e-208 ycgA - - S - - - Membrane
EPKFIKFJ_00307 1.04e-53 ycgB - - - - - - -
EPKFIKFJ_00308 2.85e-15 - - - S - - - RDD family
EPKFIKFJ_00309 1.55e-226 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
EPKFIKFJ_00310 0.0 mdr - - EGP - - - the major facilitator superfamily
EPKFIKFJ_00311 3.16e-97 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_00313 1.15e-54 ycgF - - E - - - Lysine exporter protein LysE YggA
EPKFIKFJ_00314 6.64e-76 ycgF - - E - - - Lysine exporter protein LysE YggA
EPKFIKFJ_00315 5.9e-183 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
EPKFIKFJ_00316 2.03e-305 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKFIKFJ_00317 6.25e-144 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
EPKFIKFJ_00318 2.05e-188 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EPKFIKFJ_00319 1.69e-164 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
EPKFIKFJ_00320 3.35e-288 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_00321 1.43e-134 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EPKFIKFJ_00322 9.05e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
EPKFIKFJ_00323 8.28e-178 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
EPKFIKFJ_00324 1.53e-213 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EPKFIKFJ_00325 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EPKFIKFJ_00326 1.05e-309 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKFIKFJ_00327 7.58e-286 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
EPKFIKFJ_00328 4.86e-235 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
EPKFIKFJ_00329 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EPKFIKFJ_00330 1.64e-72 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
EPKFIKFJ_00331 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EPKFIKFJ_00332 1.41e-49 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EPKFIKFJ_00333 9.85e-281 yciC - - S - - - GTPases (G3E family)
EPKFIKFJ_00334 2.62e-278 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EPKFIKFJ_00335 3.65e-94 yckC - - S - - - membrane
EPKFIKFJ_00336 7.52e-65 - - - S - - - Protein of unknown function (DUF2680)
EPKFIKFJ_00337 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKFIKFJ_00338 7.34e-86 nin - - S - - - Competence protein J (ComJ)
EPKFIKFJ_00339 2.67e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
EPKFIKFJ_00340 7.04e-121 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
EPKFIKFJ_00341 6.52e-132 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
EPKFIKFJ_00342 2.89e-84 hxlR - - K - - - transcriptional
EPKFIKFJ_00343 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_00344 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_00345 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
EPKFIKFJ_00346 1.14e-175 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
EPKFIKFJ_00347 2.92e-314 - - - E - - - Aminotransferase class I and II
EPKFIKFJ_00348 5.87e-155 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
EPKFIKFJ_00349 1.12e-137 yczE - - S ko:K07149 - ko00000 membrane
EPKFIKFJ_00350 1.32e-167 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKFIKFJ_00351 5.85e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EPKFIKFJ_00352 1.41e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
EPKFIKFJ_00353 2.91e-197 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
EPKFIKFJ_00354 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
EPKFIKFJ_00355 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
EPKFIKFJ_00356 6.46e-49 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
EPKFIKFJ_00357 8.93e-96 yclD - - - - - - -
EPKFIKFJ_00358 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
EPKFIKFJ_00359 0.0 yclG - - M - - - Pectate lyase superfamily protein
EPKFIKFJ_00361 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
EPKFIKFJ_00362 2.66e-289 gerKC - - S ko:K06297 - ko00000 spore germination
EPKFIKFJ_00363 4.89e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
EPKFIKFJ_00364 2.46e-315 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKFIKFJ_00365 2.47e-117 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKFIKFJ_00366 2.27e-176 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EPKFIKFJ_00367 1.22e-147 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EPKFIKFJ_00368 4.6e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_00369 7.36e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
EPKFIKFJ_00370 1.72e-303 yxeQ - - S - - - MmgE/PrpD family
EPKFIKFJ_00371 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
EPKFIKFJ_00372 4.84e-300 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
EPKFIKFJ_00373 2.5e-162 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_00374 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
EPKFIKFJ_00375 4.37e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EPKFIKFJ_00378 1.03e-314 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPKFIKFJ_00379 1.06e-208 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_00380 1.4e-212 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_00381 1.55e-173 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_00382 1.67e-220 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
EPKFIKFJ_00383 4.65e-312 ycnB - - EGP - - - the major facilitator superfamily
EPKFIKFJ_00384 4.78e-192 ycnC - - K - - - Transcriptional regulator
EPKFIKFJ_00385 2.68e-172 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
EPKFIKFJ_00386 2.79e-59 ycnE - - S - - - Monooxygenase
EPKFIKFJ_00387 1.08e-67 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EPKFIKFJ_00388 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKFIKFJ_00389 3.02e-278 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPKFIKFJ_00390 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKFIKFJ_00391 3.93e-189 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
EPKFIKFJ_00392 3.14e-182 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_00393 6.58e-128 ycnI - - S - - - protein conserved in bacteria
EPKFIKFJ_00394 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
EPKFIKFJ_00395 1.15e-135 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EPKFIKFJ_00396 2.18e-69 - - - - - - - -
EPKFIKFJ_00397 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
EPKFIKFJ_00398 1.96e-93 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
EPKFIKFJ_00399 2.79e-255 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
EPKFIKFJ_00400 4.09e-78 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
EPKFIKFJ_00402 2.59e-175 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EPKFIKFJ_00403 1.42e-170 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
EPKFIKFJ_00404 6.98e-267 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
EPKFIKFJ_00405 3.25e-181 ycsI - - S - - - Belongs to the D-glutamate cyclase family
EPKFIKFJ_00406 9.7e-168 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
EPKFIKFJ_00407 5.16e-226 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
EPKFIKFJ_00408 7.07e-162 kipR - - K - - - Transcriptional regulator
EPKFIKFJ_00409 9.77e-144 ycsK - - E - - - anatomical structure formation involved in morphogenesis
EPKFIKFJ_00411 6.7e-72 yczJ - - S - - - biosynthesis
EPKFIKFJ_00412 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
EPKFIKFJ_00413 7.28e-212 ycsN - - S - - - Oxidoreductase
EPKFIKFJ_00414 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
EPKFIKFJ_00415 0.0 ydaB - - IQ - - - acyl-CoA ligase
EPKFIKFJ_00416 6.33e-182 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_00417 1.08e-122 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
EPKFIKFJ_00418 1.58e-146 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPKFIKFJ_00419 4.32e-100 ydaG - - S - - - general stress protein
EPKFIKFJ_00420 9.89e-174 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
EPKFIKFJ_00421 2.67e-62 ydzA - - EGP - - - Domain of unknown function (DUF3817)
EPKFIKFJ_00422 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EPKFIKFJ_00423 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPKFIKFJ_00424 7.77e-240 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
EPKFIKFJ_00425 4.73e-183 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
EPKFIKFJ_00426 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
EPKFIKFJ_00427 1.2e-298 ydaM - - M - - - Glycosyl transferase family group 2
EPKFIKFJ_00428 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
EPKFIKFJ_00429 0.0 ydaO - - E - - - amino acid
EPKFIKFJ_00430 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
EPKFIKFJ_00431 5.03e-80 - - - K - - - acetyltransferase
EPKFIKFJ_00432 7.58e-111 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EPKFIKFJ_00433 3.09e-79 - - - - - - - -
EPKFIKFJ_00434 1.77e-235 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
EPKFIKFJ_00437 1.06e-53 - - - - - - - -
EPKFIKFJ_00438 1.47e-285 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
EPKFIKFJ_00441 4.61e-44 ydaT - - - - - - -
EPKFIKFJ_00442 6.73e-97 yvaD - - S - - - Family of unknown function (DUF5360)
EPKFIKFJ_00443 1.7e-64 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
EPKFIKFJ_00444 6.45e-174 ydbA - - P - - - EcsC protein family
EPKFIKFJ_00445 8.2e-08 gsiB - - S ko:K06884 - ko00000 general stress protein
EPKFIKFJ_00446 1.04e-75 ydbB - - G - - - Cupin domain
EPKFIKFJ_00447 6.59e-76 ydbC - - S - - - Domain of unknown function (DUF4937
EPKFIKFJ_00448 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
EPKFIKFJ_00449 8.49e-52 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EPKFIKFJ_00450 2.07e-171 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
EPKFIKFJ_00451 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EPKFIKFJ_00452 2.66e-146 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EPKFIKFJ_00453 3.75e-285 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKFIKFJ_00454 1.85e-225 ydbI - - S - - - AI-2E family transporter
EPKFIKFJ_00455 1.79e-216 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_00456 5.5e-164 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPKFIKFJ_00457 1.32e-69 ydbL - - - - - - -
EPKFIKFJ_00458 7.84e-256 ydbM - - I - - - acyl-CoA dehydrogenase
EPKFIKFJ_00459 2.36e-17 - - - S - - - Fur-regulated basic protein B
EPKFIKFJ_00460 6.11e-15 - - - S - - - Fur-regulated basic protein A
EPKFIKFJ_00461 1.34e-158 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPKFIKFJ_00462 2.25e-74 ydbP - - CO - - - Thioredoxin
EPKFIKFJ_00463 7.23e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
EPKFIKFJ_00464 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPKFIKFJ_00465 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EPKFIKFJ_00466 6.7e-93 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
EPKFIKFJ_00467 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
EPKFIKFJ_00468 8.15e-136 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
EPKFIKFJ_00469 4.96e-72 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPKFIKFJ_00470 1.18e-230 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
EPKFIKFJ_00471 3.01e-274 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPKFIKFJ_00472 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
EPKFIKFJ_00473 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
EPKFIKFJ_00474 9.89e-176 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
EPKFIKFJ_00475 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
EPKFIKFJ_00476 5.79e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
EPKFIKFJ_00477 4.02e-238 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
EPKFIKFJ_00478 1.34e-68 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
EPKFIKFJ_00479 6.83e-109 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
EPKFIKFJ_00480 2.67e-179 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKFIKFJ_00481 3.58e-135 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
EPKFIKFJ_00482 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
EPKFIKFJ_00483 1.78e-21 - - - - - - - -
EPKFIKFJ_00484 6.69e-104 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
EPKFIKFJ_00492 5.14e-10 - - - S - - - YvrJ protein family
EPKFIKFJ_00493 4.24e-62 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_00497 4.65e-40 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EPKFIKFJ_00500 6.4e-31 - - - S - - - YesK-like protein
EPKFIKFJ_00501 1.31e-246 ydcL - - L - - - Belongs to the 'phage' integrase family
EPKFIKFJ_00502 9.84e-80 - - - E - - - Pfam:DUF955
EPKFIKFJ_00503 4.29e-71 - - - K - - - Transcriptional
EPKFIKFJ_00504 2.18e-34 - - - - - - - -
EPKFIKFJ_00506 1.87e-50 - - - S - - - Bacterial protein of unknown function (DUF961)
EPKFIKFJ_00508 1.56e-302 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
EPKFIKFJ_00509 7.64e-231 nicK - - L ko:K07467 - ko00000 Replication initiation factor
EPKFIKFJ_00513 8.19e-49 yddA - - - - - - -
EPKFIKFJ_00517 7.38e-165 yddB - - S - - - Conjugative transposon protein TcpC
EPKFIKFJ_00518 2.72e-33 yddC - - - - - - -
EPKFIKFJ_00519 1.85e-97 yddD - - S - - - TcpE family
EPKFIKFJ_00520 0.0 yddE - - S - - - AAA-like domain
EPKFIKFJ_00521 1.37e-47 - - - S - - - Domain of unknown function (DUF1874)
EPKFIKFJ_00522 6.43e-261 yddG - - S - - - maturation of SSU-rRNA
EPKFIKFJ_00523 1.46e-200 yddH - - M - - - Lysozyme-like
EPKFIKFJ_00524 1.89e-73 yddI - - - - - - -
EPKFIKFJ_00525 1.77e-47 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
EPKFIKFJ_00526 4.06e-75 - - - - - - - -
EPKFIKFJ_00530 1.41e-181 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
EPKFIKFJ_00531 7.54e-91 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKFIKFJ_00533 1.5e-65 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
EPKFIKFJ_00534 2.4e-253 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
EPKFIKFJ_00535 7.99e-71 - - - - - - - -
EPKFIKFJ_00536 1.19e-99 - - - K - - - Transcriptional regulator
EPKFIKFJ_00537 7.03e-123 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPKFIKFJ_00538 3.05e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
EPKFIKFJ_00539 2.64e-143 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EPKFIKFJ_00540 1e-131 - - - S - - - Protein of unknown function (DUF2812)
EPKFIKFJ_00541 6.49e-65 - - - K - - - Transcriptional regulator PadR-like family
EPKFIKFJ_00542 1.99e-300 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKFIKFJ_00543 3.96e-238 ydeG - - EGP - - - Major facilitator superfamily
EPKFIKFJ_00544 1.41e-63 - - - S - - - Patatin-like phospholipase
EPKFIKFJ_00545 5.81e-57 - - - S - - - Patatin-like phospholipase
EPKFIKFJ_00547 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
EPKFIKFJ_00548 2.6e-90 - - - E ko:K07032 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKFIKFJ_00549 8.48e-196 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
EPKFIKFJ_00550 3.58e-201 - - - S - - - SNARE associated Golgi protein
EPKFIKFJ_00551 1.19e-124 yrkC - - G - - - Cupin domain
EPKFIKFJ_00552 1.75e-106 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EPKFIKFJ_00553 1.73e-186 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
EPKFIKFJ_00555 1.4e-238 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
EPKFIKFJ_00556 7.14e-63 ydeH - - - - - - -
EPKFIKFJ_00557 3.65e-206 - - - S - - - Sodium Bile acid symporter family
EPKFIKFJ_00558 1.96e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
EPKFIKFJ_00559 3.59e-78 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
EPKFIKFJ_00560 6.33e-278 nhaC_1 - - C - - - antiporter
EPKFIKFJ_00561 1.34e-313 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
EPKFIKFJ_00562 1.74e-129 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_00563 1.41e-239 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
EPKFIKFJ_00564 2.13e-129 ydeS - - K - - - Transcriptional regulator
EPKFIKFJ_00565 2.99e-192 ydeK - - EG - - - -transporter
EPKFIKFJ_00566 1.8e-316 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKFIKFJ_00567 1.16e-62 yraD - - M ko:K06439 - ko00000 Spore coat protein
EPKFIKFJ_00568 4.86e-33 yraE - - - ko:K06440 - ko00000 -
EPKFIKFJ_00569 3.98e-278 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
EPKFIKFJ_00570 4.76e-84 yraF - - M - - - Spore coat protein
EPKFIKFJ_00571 4.73e-47 yraG - - - ko:K06440 - ko00000 -
EPKFIKFJ_00572 6.26e-42 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
EPKFIKFJ_00573 3.37e-162 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
EPKFIKFJ_00574 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
EPKFIKFJ_00575 4.32e-117 ynaD - - J - - - Acetyltransferase (GNAT) domain
EPKFIKFJ_00576 1.37e-188 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKFIKFJ_00577 1.89e-248 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
EPKFIKFJ_00578 4.16e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EPKFIKFJ_00579 4.68e-280 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPKFIKFJ_00580 7.19e-197 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_00581 1.05e-156 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
EPKFIKFJ_00582 2.24e-101 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
EPKFIKFJ_00583 1.6e-181 bltR - - K - - - helix_turn_helix, mercury resistance
EPKFIKFJ_00584 3.72e-184 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EPKFIKFJ_00585 1.15e-138 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
EPKFIKFJ_00586 4.22e-132 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
EPKFIKFJ_00587 1.24e-208 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
EPKFIKFJ_00588 1.47e-144 ydhC - - K - - - FCD
EPKFIKFJ_00589 8.62e-69 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EPKFIKFJ_00590 1.11e-168 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EPKFIKFJ_00592 3.98e-311 pbpE - - V - - - Beta-lactamase
EPKFIKFJ_00594 5.02e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
EPKFIKFJ_00595 1.24e-244 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
EPKFIKFJ_00596 3.82e-167 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
EPKFIKFJ_00597 1.12e-145 - - - K ko:K05799 - ko00000,ko03000 FCD
EPKFIKFJ_00598 1.35e-264 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
EPKFIKFJ_00599 2.88e-63 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
EPKFIKFJ_00600 4.14e-63 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EPKFIKFJ_00601 1.07e-128 yvdT_1 - - K - - - Transcriptional regulator
EPKFIKFJ_00602 0.0 ybeC - - E - - - amino acid
EPKFIKFJ_00603 4.74e-209 ydhU - - P ko:K07217 - ko00000 Catalase
EPKFIKFJ_00604 2.82e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
EPKFIKFJ_00605 7.98e-228 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
EPKFIKFJ_00606 4.86e-313 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKFIKFJ_00609 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00612 4.4e-221 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EPKFIKFJ_00613 1.44e-109 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
EPKFIKFJ_00614 2.69e-158 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
EPKFIKFJ_00615 5.74e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EPKFIKFJ_00616 2.83e-239 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPKFIKFJ_00617 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
EPKFIKFJ_00618 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EPKFIKFJ_00619 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EPKFIKFJ_00620 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
EPKFIKFJ_00621 2.61e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EPKFIKFJ_00622 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
EPKFIKFJ_00623 9.24e-162 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
EPKFIKFJ_00624 1.24e-57 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPKFIKFJ_00625 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPKFIKFJ_00626 1.16e-43 - - - L - - - Arm DNA-binding domain
EPKFIKFJ_00627 3.68e-35 xkdA - - E - - - IrrE N-terminal-like domain
EPKFIKFJ_00628 4.09e-50 - - - S - - - Protein of unknown function (DUF4064)
EPKFIKFJ_00629 8.41e-82 - - - - - - - -
EPKFIKFJ_00630 3.22e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_00631 1.73e-18 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_00632 2.39e-48 - - - - - - - -
EPKFIKFJ_00633 4.76e-76 - - - S - - - DNA binding
EPKFIKFJ_00634 3.27e-110 - - - - - - - -
EPKFIKFJ_00638 1.09e-192 yqaJ - - L - - - YqaJ-like viral recombinase domain
EPKFIKFJ_00639 3.37e-162 recT - - L ko:K07455 - ko00000,ko03400 RecT family
EPKFIKFJ_00640 4.55e-36 yqaL - - L - - - DnaD domain protein
EPKFIKFJ_00641 1.54e-152 yqaM - - L - - - IstB-like ATP binding protein
EPKFIKFJ_00643 5.52e-28 - - - S - - - YopX protein
EPKFIKFJ_00644 1.57e-71 - - - S - - - Protein of unknown function (DUF1064)
EPKFIKFJ_00646 1.16e-23 yqaO - - S - - - Phage-like element PBSX protein XtrA
EPKFIKFJ_00649 4.72e-217 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EPKFIKFJ_00651 2.08e-54 - - - S - - - dUTPase
EPKFIKFJ_00654 2.62e-08 - - - S - - - YopX protein
EPKFIKFJ_00659 3.27e-63 - - - - - - - -
EPKFIKFJ_00661 1.76e-22 - - - V - - - VanZ like family
EPKFIKFJ_00662 5.88e-88 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EPKFIKFJ_00664 1.74e-17 - - - K - - - Transcriptional regulator
EPKFIKFJ_00667 7.49e-103 yqaS - - L - - - DNA packaging
EPKFIKFJ_00668 9.66e-225 - - - S - - - Pfam:Terminase_3C
EPKFIKFJ_00669 9.32e-157 - - - S - - - Phage portal protein, SPP1 Gp6-like
EPKFIKFJ_00670 1.53e-116 - - - S - - - Phage Mu protein F like protein
EPKFIKFJ_00672 3.82e-56 - - - S - - - Phage minor structural protein GP20
EPKFIKFJ_00673 1.85e-61 - - - S - - - viral capsid
EPKFIKFJ_00676 2.05e-36 - - - S - - - Phage gp6-like head-tail connector protein
EPKFIKFJ_00677 7.37e-38 - - - S - - - Phage head-tail joining protein
EPKFIKFJ_00678 1.29e-49 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EPKFIKFJ_00679 1.14e-37 - - - S - - - Protein of unknown function (DUF3168)
EPKFIKFJ_00680 3.23e-44 - - - S - - - Phage tail tube protein
EPKFIKFJ_00682 3.59e-186 - - - - - - - -
EPKFIKFJ_00684 2.51e-246 - - - L - - - Phage minor structural protein
EPKFIKFJ_00688 1.19e-40 xhlA - - S - - - Haemolysin XhlA
EPKFIKFJ_00689 2.07e-37 xhlB - - S - - - SPP1 phage holin
EPKFIKFJ_00690 2e-155 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_00693 0.0 ykuG - - M - - - Putative peptidoglycan binding domain
EPKFIKFJ_00695 2.21e-81 - - - - - - - -
EPKFIKFJ_00696 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
EPKFIKFJ_00697 9.34e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
EPKFIKFJ_00698 9.02e-311 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
EPKFIKFJ_00699 4.48e-211 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
EPKFIKFJ_00700 1.47e-40 yjdJ - - S - - - Domain of unknown function (DUF4306)
EPKFIKFJ_00701 4.36e-143 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
EPKFIKFJ_00702 6.45e-222 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPKFIKFJ_00703 3.97e-156 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
EPKFIKFJ_00704 4.64e-200 ydjI - - S - - - virion core protein (lumpy skin disease virus)
EPKFIKFJ_00705 0.0 oatA - - I - - - Acyltransferase family
EPKFIKFJ_00706 5.52e-184 rsiV - - S - - - Protein of unknown function (DUF3298)
EPKFIKFJ_00707 1.08e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKFIKFJ_00708 7.9e-246 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EPKFIKFJ_00709 7.91e-83 ydjM - - M - - - Lytic transglycolase
EPKFIKFJ_00710 1.51e-189 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
EPKFIKFJ_00712 9.6e-47 ydjO - - S - - - Cold-inducible protein YdjO
EPKFIKFJ_00713 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
EPKFIKFJ_00714 2.56e-307 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKFIKFJ_00715 7.59e-180 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPKFIKFJ_00716 7.99e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
EPKFIKFJ_00717 1e-254 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
EPKFIKFJ_00718 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
EPKFIKFJ_00719 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
EPKFIKFJ_00720 8.68e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKFIKFJ_00721 0.0 - - - S - - - Domain of unknown function (DUF4179)
EPKFIKFJ_00722 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
EPKFIKFJ_00723 6.92e-165 yebC - - M - - - Membrane
EPKFIKFJ_00725 1.08e-119 yebE - - S - - - UPF0316 protein
EPKFIKFJ_00726 1.88e-39 yebG - - S - - - NETI protein
EPKFIKFJ_00727 1.87e-107 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPKFIKFJ_00728 1.15e-280 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPKFIKFJ_00729 1.05e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPKFIKFJ_00730 3.8e-163 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
EPKFIKFJ_00731 2.57e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPKFIKFJ_00732 4.32e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPKFIKFJ_00733 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPKFIKFJ_00734 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPKFIKFJ_00735 2.08e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
EPKFIKFJ_00736 1.16e-133 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPKFIKFJ_00737 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
EPKFIKFJ_00738 2.12e-293 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
EPKFIKFJ_00739 4.48e-81 - - - K - - - helix_turn_helix ASNC type
EPKFIKFJ_00740 3.96e-173 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
EPKFIKFJ_00741 2.05e-33 - - - S - - - Protein of unknown function (DUF2892)
EPKFIKFJ_00742 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
EPKFIKFJ_00743 2.74e-243 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
EPKFIKFJ_00744 2.03e-67 yerC - - S - - - protein conserved in bacteria
EPKFIKFJ_00745 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
EPKFIKFJ_00746 5.04e-163 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
EPKFIKFJ_00747 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
EPKFIKFJ_00748 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPKFIKFJ_00749 1.59e-285 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
EPKFIKFJ_00750 6.11e-231 yerI - - S - - - homoserine kinase type II (protein kinase fold)
EPKFIKFJ_00751 7.98e-156 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EPKFIKFJ_00752 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKFIKFJ_00753 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPKFIKFJ_00754 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPKFIKFJ_00755 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPKFIKFJ_00756 1.01e-189 yerO - - K - - - Transcriptional regulator
EPKFIKFJ_00757 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EPKFIKFJ_00758 8.56e-217 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EPKFIKFJ_00759 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPKFIKFJ_00760 0.0 - - - L ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
EPKFIKFJ_00761 2.88e-204 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EPKFIKFJ_00762 3.92e-175 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
EPKFIKFJ_00763 2.52e-43 - - - S - - - Protein of unknown function, DUF600
EPKFIKFJ_00764 2.35e-73 - - - S - - - Protein of unknown function, DUF600
EPKFIKFJ_00765 2.48e-66 - - - S - - - Protein of unknown function, DUF600
EPKFIKFJ_00766 1.69e-257 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
EPKFIKFJ_00767 6.14e-152 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
EPKFIKFJ_00768 1.27e-161 yeeN - - K - - - transcriptional regulatory protein
EPKFIKFJ_00770 2.48e-138 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
EPKFIKFJ_00771 1.32e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
EPKFIKFJ_00772 1.34e-60 cotJB - - S ko:K06333 - ko00000 CotJB protein
EPKFIKFJ_00773 4.26e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
EPKFIKFJ_00774 1.38e-114 yesJ - - K - - - Acetyltransferase (GNAT) family
EPKFIKFJ_00776 1.26e-147 yetF - - S - - - membrane
EPKFIKFJ_00777 3.06e-70 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
EPKFIKFJ_00778 2.87e-82 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKFIKFJ_00779 2.4e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKFIKFJ_00780 7.84e-29 - - - S - - - Uncharacterized small protein (DUF2292)
EPKFIKFJ_00781 2.59e-73 - - - H - - - riboflavin kinase activity
EPKFIKFJ_00782 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
EPKFIKFJ_00783 3.05e-110 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_00784 3.35e-246 yetM - - CH - - - FAD binding domain
EPKFIKFJ_00785 2.78e-251 yetN - - S - - - Protein of unknown function (DUF3900)
EPKFIKFJ_00786 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EPKFIKFJ_00788 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EPKFIKFJ_00789 1.4e-186 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
EPKFIKFJ_00790 5.59e-219 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
EPKFIKFJ_00791 7.97e-222 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
EPKFIKFJ_00792 7.97e-273 yfnE - - S - - - Glycosyltransferase like family 2
EPKFIKFJ_00793 5.43e-227 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
EPKFIKFJ_00794 1.12e-270 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_00795 2.1e-306 yfnA - - E ko:K03294 - ko00000 amino acid
EPKFIKFJ_00796 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKFIKFJ_00797 3.69e-165 yfmS - - NT - - - chemotaxis protein
EPKFIKFJ_00798 1.93e-211 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPKFIKFJ_00799 4.84e-256 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKFIKFJ_00800 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPKFIKFJ_00801 8.36e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
EPKFIKFJ_00802 3.06e-249 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
EPKFIKFJ_00803 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPKFIKFJ_00804 4.02e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
EPKFIKFJ_00805 3.25e-64 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EPKFIKFJ_00806 1.41e-99 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
EPKFIKFJ_00807 9.03e-33 - - - S - - - Protein of unknown function (DUF3212)
EPKFIKFJ_00808 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
EPKFIKFJ_00809 5.26e-298 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EPKFIKFJ_00810 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
EPKFIKFJ_00814 7.64e-93 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
EPKFIKFJ_00815 0.0 ywpD - - T - - - Histidine kinase
EPKFIKFJ_00816 4.78e-191 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
EPKFIKFJ_00817 0.0 - - - M - - - cell wall anchor domain
EPKFIKFJ_00818 5.54e-104 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
EPKFIKFJ_00819 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EPKFIKFJ_00820 4.96e-148 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
EPKFIKFJ_00821 1.36e-217 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
EPKFIKFJ_00822 4.33e-282 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EPKFIKFJ_00823 3.39e-183 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKFIKFJ_00824 7.02e-269 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
EPKFIKFJ_00825 4.43e-56 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
EPKFIKFJ_00826 1.9e-153 yflK - - S - - - protein conserved in bacteria
EPKFIKFJ_00827 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
EPKFIKFJ_00828 5.69e-26 yflI - - - - - - -
EPKFIKFJ_00829 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
EPKFIKFJ_00830 1.05e-174 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
EPKFIKFJ_00831 9.77e-313 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
EPKFIKFJ_00832 8.21e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
EPKFIKFJ_00833 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
EPKFIKFJ_00834 3.87e-80 ydhN1 - - S - - - Domain of unknown function (DUF1992)
EPKFIKFJ_00835 2.68e-100 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EPKFIKFJ_00836 6.73e-51 ydgA - - S - - - Spore germination protein gerPA/gerPF
EPKFIKFJ_00837 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
EPKFIKFJ_00838 7.43e-312 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_00839 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
EPKFIKFJ_00840 2.03e-162 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
EPKFIKFJ_00841 1.34e-154 frp - - C - - - nitroreductase
EPKFIKFJ_00842 1.06e-160 yibF - - S - - - YibE/F-like protein
EPKFIKFJ_00843 5.49e-235 yibE - - S - - - YibE/F-like protein
EPKFIKFJ_00844 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
EPKFIKFJ_00845 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EPKFIKFJ_00846 2.99e-228 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EPKFIKFJ_00847 1.61e-205 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPKFIKFJ_00848 5.75e-165 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EPKFIKFJ_00849 1.23e-245 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_00850 7.02e-40 yfkK - - S - - - Belongs to the UPF0435 family
EPKFIKFJ_00851 1.38e-102 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPKFIKFJ_00852 2.71e-63 yfkI - - S - - - gas vesicle protein
EPKFIKFJ_00853 8.85e-182 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
EPKFIKFJ_00854 1.55e-273 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_00855 3.14e-234 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
EPKFIKFJ_00856 4.99e-180 yfkD - - S - - - YfkD-like protein
EPKFIKFJ_00857 5.34e-182 yfkC - - M - - - Mechanosensitive ion channel
EPKFIKFJ_00858 9.38e-279 yfkA - - S - - - YfkB-like domain
EPKFIKFJ_00859 7.99e-37 yfjT - - - - - - -
EPKFIKFJ_00860 4.19e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
EPKFIKFJ_00861 7.52e-57 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EPKFIKFJ_00862 3.36e-87 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
EPKFIKFJ_00864 5.27e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
EPKFIKFJ_00865 5.07e-201 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EPKFIKFJ_00866 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPKFIKFJ_00867 3.05e-93 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
EPKFIKFJ_00868 5.62e-307 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EPKFIKFJ_00869 0.0 - - - KLT - - - Protein kinase domain
EPKFIKFJ_00877 1.83e-60 - - - S - - - YfzA-like protein
EPKFIKFJ_00878 7.85e-241 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPKFIKFJ_00879 2.86e-102 yfjM - - S - - - Psort location Cytoplasmic, score
EPKFIKFJ_00880 2.95e-239 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPKFIKFJ_00881 9.85e-238 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPKFIKFJ_00882 7.82e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPKFIKFJ_00883 3.32e-302 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPKFIKFJ_00884 8.68e-198 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EPKFIKFJ_00885 1.46e-136 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
EPKFIKFJ_00886 3.29e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
EPKFIKFJ_00887 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EPKFIKFJ_00888 3.67e-177 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
EPKFIKFJ_00889 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_00890 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
EPKFIKFJ_00891 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
EPKFIKFJ_00892 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKFIKFJ_00893 7.86e-82 yfiD3 - - S - - - DoxX
EPKFIKFJ_00894 5.91e-199 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
EPKFIKFJ_00895 2.12e-99 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EPKFIKFJ_00896 1.49e-89 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EPKFIKFJ_00897 1e-119 padR - - K - - - transcriptional
EPKFIKFJ_00898 1.83e-128 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EPKFIKFJ_00899 2.39e-223 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
EPKFIKFJ_00900 1.37e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EPKFIKFJ_00901 2.04e-122 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
EPKFIKFJ_00902 0.0 yfiU - - EGP - - - the major facilitator superfamily
EPKFIKFJ_00903 2.11e-103 yfiV - - K - - - transcriptional
EPKFIKFJ_00904 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPKFIKFJ_00905 1.27e-193 yfhB - - S - - - PhzF family
EPKFIKFJ_00906 3.09e-133 yfhC - - C - - - nitroreductase
EPKFIKFJ_00907 6.01e-33 yfhD - - S - - - YfhD-like protein
EPKFIKFJ_00909 3.2e-210 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
EPKFIKFJ_00910 1.95e-177 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
EPKFIKFJ_00911 3.93e-61 yfhH - - S - - - Protein of unknown function (DUF1811)
EPKFIKFJ_00912 6.7e-231 yfhI - - EGP - - - -transporter
EPKFIKFJ_00914 6.34e-201 mpr - - M - - - Belongs to the peptidase S1B family
EPKFIKFJ_00915 1.49e-58 yfhJ - - S - - - WVELL protein
EPKFIKFJ_00916 2.3e-112 yfhK - - T - - - Bacterial SH3 domain homologues
EPKFIKFJ_00917 1.7e-47 yfhL - - S - - - SdpI/YhfL protein family
EPKFIKFJ_00918 5.37e-156 - - - S - - - Alpha/beta hydrolase family
EPKFIKFJ_00919 1.29e-234 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKFIKFJ_00920 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
EPKFIKFJ_00921 4.29e-229 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
EPKFIKFJ_00922 3.84e-258 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
EPKFIKFJ_00923 1.47e-49 yfhS - - - - - - -
EPKFIKFJ_00924 1.73e-169 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_00925 9.58e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
EPKFIKFJ_00926 1.4e-49 ygaB - - S - - - YgaB-like protein
EPKFIKFJ_00927 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
EPKFIKFJ_00928 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
EPKFIKFJ_00929 1.76e-237 ygaE - - S - - - Membrane
EPKFIKFJ_00930 1.27e-309 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EPKFIKFJ_00931 7.73e-109 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
EPKFIKFJ_00932 6.8e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
EPKFIKFJ_00933 1.1e-73 ygzB - - S - - - UPF0295 protein
EPKFIKFJ_00934 2.08e-208 ygxA - - S - - - Nucleotidyltransferase-like
EPKFIKFJ_00935 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_00952 5.85e-167 - - - L - - - Phage integrase family
EPKFIKFJ_00953 1.4e-90 - - - - - - - -
EPKFIKFJ_00956 6.42e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_00957 4.18e-07 ahdIC - - K - - - PFAM helix-turn-helix domain protein
EPKFIKFJ_00958 6.41e-50 - - - S - - - Domain of unknown function (DUF771)
EPKFIKFJ_00960 3.44e-116 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
EPKFIKFJ_00961 2.62e-40 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
EPKFIKFJ_00963 2.96e-08 - - - - - - - -
EPKFIKFJ_00964 4.2e-36 - - - - - - - -
EPKFIKFJ_00967 2.26e-21 yqaO - - S - - - Phage-like element PBSX protein XtrA
EPKFIKFJ_00969 2.37e-36 - - - - - - - -
EPKFIKFJ_00971 8.57e-216 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EPKFIKFJ_00973 4.86e-59 - - - S - - - dUTPase
EPKFIKFJ_00978 4.1e-70 - - - M - - - ArpU family transcriptional regulator
EPKFIKFJ_00979 2.64e-93 - - - L - - - Phage integrase family
EPKFIKFJ_00980 2.7e-11 ftsK - - D ko:K03466 - ko00000,ko03036 PFAM cell divisionFtsK SpoIIIE
EPKFIKFJ_00984 5.24e-22 - - - V - - - HNH endonuclease
EPKFIKFJ_00985 3.68e-59 - - - - - - - -
EPKFIKFJ_00986 0.0 - - - L - - - Phage Terminase
EPKFIKFJ_00987 1.71e-227 - - - S - - - Phage portal protein
EPKFIKFJ_00988 4.57e-108 - - - OU - - - Clp protease
EPKFIKFJ_00989 5.24e-187 - - - S - - - Phage capsid family
EPKFIKFJ_00990 2.56e-05 - - - - - - - -
EPKFIKFJ_00991 2.88e-29 - - - - - - - -
EPKFIKFJ_00992 3.54e-30 - - - S - - - Phage head-tail joining protein
EPKFIKFJ_00994 3.28e-13 - - - S - - - TIGRFAM phage protein, HK97 gp10 family
EPKFIKFJ_00995 8.37e-21 - - - N - - - Maj_tail_phi13 phage major tail , phi13 family protein
EPKFIKFJ_00996 4.76e-05 - - - - - - - -
EPKFIKFJ_00998 3.49e-169 - - - D - - - phage tail tape measure protein
EPKFIKFJ_01000 3e-122 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
EPKFIKFJ_01001 0.0 - - - M - - - Pectate lyase superfamily protein
EPKFIKFJ_01002 6.24e-220 - - - S - - - Domain of unknown function (DUF2479)
EPKFIKFJ_01004 5.7e-14 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
EPKFIKFJ_01005 2.01e-79 - - - S - - - Pfam:Phage_holin_4_1
EPKFIKFJ_01006 3.15e-87 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
EPKFIKFJ_01007 5.89e-23 - - - - - - - -
EPKFIKFJ_01008 1.88e-51 - - - - - - - -
EPKFIKFJ_01010 0.0 - - - C - - - Na+/H+ antiporter family
EPKFIKFJ_01011 2.38e-158 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
EPKFIKFJ_01012 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EPKFIKFJ_01013 3.15e-313 ygaK - - C - - - Berberine and berberine like
EPKFIKFJ_01015 6.85e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
EPKFIKFJ_01016 2.33e-185 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKFIKFJ_01017 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKFIKFJ_01018 5.45e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01019 5.17e-165 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01020 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EPKFIKFJ_01021 2.39e-227 - - - S ko:K07045 - ko00000 Amidohydrolase
EPKFIKFJ_01022 1.02e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
EPKFIKFJ_01023 5.5e-217 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
EPKFIKFJ_01024 6.5e-183 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EPKFIKFJ_01025 5.74e-266 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
EPKFIKFJ_01027 1.62e-53 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPKFIKFJ_01028 2.4e-102 ygaO - - - - - - -
EPKFIKFJ_01029 5.45e-31 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_01031 1.34e-138 yhzB - - S - - - B3/4 domain
EPKFIKFJ_01032 2.14e-280 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EPKFIKFJ_01033 8.37e-216 yhbB - - S - - - Putative amidase domain
EPKFIKFJ_01034 2.31e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPKFIKFJ_01035 3.35e-132 yhbD - - K - - - Protein of unknown function (DUF4004)
EPKFIKFJ_01036 2.51e-76 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EPKFIKFJ_01037 7.48e-85 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
EPKFIKFJ_01038 1.23e-07 - - - - - - - -
EPKFIKFJ_01039 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
EPKFIKFJ_01040 1.74e-275 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
EPKFIKFJ_01041 5.43e-94 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
EPKFIKFJ_01042 2.98e-130 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
EPKFIKFJ_01043 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
EPKFIKFJ_01044 2.61e-128 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
EPKFIKFJ_01045 1.03e-65 yhcC - - - - - - -
EPKFIKFJ_01046 7.54e-65 - - - - - - - -
EPKFIKFJ_01047 3.06e-77 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_01048 8.89e-147 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_01049 3.74e-212 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_01050 1.87e-201 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
EPKFIKFJ_01051 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
EPKFIKFJ_01052 6.9e-161 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
EPKFIKFJ_01053 2.76e-230 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
EPKFIKFJ_01054 1.01e-290 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKFIKFJ_01055 1.79e-49 - 3.5.1.6, 3.5.1.87 - E ko:K06016 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EPKFIKFJ_01056 5.08e-60 yhcM - - - - - - -
EPKFIKFJ_01057 6.26e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKFIKFJ_01058 3.99e-199 yhcP - - - - - - -
EPKFIKFJ_01059 2.2e-149 yhcQ - - M - - - Spore coat protein
EPKFIKFJ_01060 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EPKFIKFJ_01061 3.17e-128 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
EPKFIKFJ_01062 2.24e-207 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EPKFIKFJ_01063 1.88e-83 yhcU - - S - - - Family of unknown function (DUF5365)
EPKFIKFJ_01064 5.88e-89 yhcV - - S - - - COG0517 FOG CBS domain
EPKFIKFJ_01065 1.33e-158 yhcW - - S ko:K07025 - ko00000 hydrolase
EPKFIKFJ_01066 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EPKFIKFJ_01067 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPKFIKFJ_01068 2.26e-129 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
EPKFIKFJ_01069 2.6e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
EPKFIKFJ_01070 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPKFIKFJ_01071 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EPKFIKFJ_01072 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
EPKFIKFJ_01073 2.73e-247 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_01074 5.61e-139 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKFIKFJ_01075 2.89e-108 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
EPKFIKFJ_01076 1.16e-51 yhdB - - S - - - YhdB-like protein
EPKFIKFJ_01077 2.33e-68 yhdC - - S - - - Protein of unknown function (DUF3889)
EPKFIKFJ_01078 1.69e-282 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EPKFIKFJ_01079 8.6e-93 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
EPKFIKFJ_01080 5.72e-314 ygxB - - M - - - Conserved TM helix
EPKFIKFJ_01081 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
EPKFIKFJ_01082 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
EPKFIKFJ_01083 2.28e-166 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EPKFIKFJ_01084 4.86e-201 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_01085 2.19e-250 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EPKFIKFJ_01086 3.42e-200 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_01087 4.47e-311 yhdG - - E ko:K03294 - ko00000 amino acid
EPKFIKFJ_01088 4.63e-264 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EPKFIKFJ_01089 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
EPKFIKFJ_01090 2.03e-249 yhdL - - S - - - Sigma factor regulator N-terminal
EPKFIKFJ_01091 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKFIKFJ_01092 4.04e-136 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EPKFIKFJ_01093 2.66e-305 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKFIKFJ_01094 2.3e-91 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
EPKFIKFJ_01095 2.3e-276 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EPKFIKFJ_01096 7.35e-290 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPKFIKFJ_01097 5.48e-314 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKFIKFJ_01098 1.68e-69 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPKFIKFJ_01099 4.22e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPKFIKFJ_01100 1.26e-156 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EPKFIKFJ_01101 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
EPKFIKFJ_01102 5.39e-252 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
EPKFIKFJ_01103 3.53e-172 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
EPKFIKFJ_01104 6.85e-192 nodB1 - - G - - - deacetylase
EPKFIKFJ_01105 1.05e-191 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
EPKFIKFJ_01106 9.13e-126 pksA - - K - - - Transcriptional regulator
EPKFIKFJ_01107 1.17e-118 ymcC - - S - - - Membrane
EPKFIKFJ_01108 3.96e-107 - - - T - - - universal stress protein
EPKFIKFJ_01109 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKFIKFJ_01110 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
EPKFIKFJ_01111 9.64e-127 yheG - - GM - - - NAD(P)H-binding
EPKFIKFJ_01113 1.91e-38 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
EPKFIKFJ_01114 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
EPKFIKFJ_01115 5.52e-316 yheD - - HJ - - - YheC/D like ATP-grasp
EPKFIKFJ_01116 2.7e-257 yheC - - HJ - - - YheC/D like ATP-grasp
EPKFIKFJ_01117 3.13e-254 yheB - - S - - - Belongs to the UPF0754 family
EPKFIKFJ_01118 5.48e-69 yheA - - S - - - Belongs to the UPF0342 family
EPKFIKFJ_01119 2.49e-197 yhaX - - S - - - haloacid dehalogenase-like hydrolase
EPKFIKFJ_01120 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
EPKFIKFJ_01121 1.48e-311 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
EPKFIKFJ_01122 9.07e-263 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
EPKFIKFJ_01123 6.25e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EPKFIKFJ_01125 4.59e-172 yhaR - - I - - - enoyl-CoA hydratase
EPKFIKFJ_01126 1.21e-20 - - - S - - - YhzD-like protein
EPKFIKFJ_01127 3.45e-209 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_01128 2.67e-274 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
EPKFIKFJ_01129 3.8e-293 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
EPKFIKFJ_01130 0.0 yhaN - - L - - - AAA domain
EPKFIKFJ_01131 3.38e-224 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
EPKFIKFJ_01132 8.23e-43 yhaL - - S - - - Sporulation protein YhaL
EPKFIKFJ_01133 3.2e-182 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EPKFIKFJ_01134 4.32e-122 yhaK - - S - - - Putative zincin peptidase
EPKFIKFJ_01135 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
EPKFIKFJ_01136 1.07e-142 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
EPKFIKFJ_01137 1.58e-53 yhaH - - S - - - YtxH-like protein
EPKFIKFJ_01138 2.55e-24 - - - - - - - -
EPKFIKFJ_01139 1.12e-97 trpP - - S - - - Tryptophan transporter TrpP
EPKFIKFJ_01140 1.49e-252 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPKFIKFJ_01141 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EPKFIKFJ_01142 2.13e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
EPKFIKFJ_01143 3.4e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
EPKFIKFJ_01144 9.96e-152 ecsC - - S - - - EcsC protein family
EPKFIKFJ_01145 1.68e-274 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EPKFIKFJ_01146 1.65e-303 yhfA - - C - - - membrane
EPKFIKFJ_01147 2.98e-115 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
EPKFIKFJ_01148 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EPKFIKFJ_01149 9.19e-253 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EPKFIKFJ_01150 3.4e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
EPKFIKFJ_01151 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
EPKFIKFJ_01152 5.15e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_01153 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
EPKFIKFJ_01154 2.04e-226 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPKFIKFJ_01156 1.66e-247 yhfE - - G - - - peptidase M42
EPKFIKFJ_01157 3.75e-286 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPKFIKFJ_01158 2.4e-173 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
EPKFIKFJ_01159 1.07e-240 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
EPKFIKFJ_01160 3.92e-137 yhfK - - GM - - - NmrA-like family
EPKFIKFJ_01161 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EPKFIKFJ_01162 9.31e-84 yhfM - - - - - - -
EPKFIKFJ_01163 1.33e-293 yhfN - - O - - - Peptidase M48
EPKFIKFJ_01164 1.24e-258 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKFIKFJ_01165 1.78e-163 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
EPKFIKFJ_01166 4.57e-129 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
EPKFIKFJ_01167 8.49e-245 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EPKFIKFJ_01168 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
EPKFIKFJ_01169 2.32e-110 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
EPKFIKFJ_01170 2.08e-272 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
EPKFIKFJ_01171 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
EPKFIKFJ_01172 2.73e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_01173 5.49e-42 yhzC - - S - - - IDEAL
EPKFIKFJ_01174 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
EPKFIKFJ_01175 4.21e-74 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
EPKFIKFJ_01176 1.28e-213 - - - S - - - Acetyltransferase, GNAT family
EPKFIKFJ_01177 3.92e-157 yrpD - - S - - - Domain of unknown function, YrpD
EPKFIKFJ_01178 7.11e-57 yhjA - - S - - - Excalibur calcium-binding domain
EPKFIKFJ_01179 2.64e-63 - - - S - - - Belongs to the UPF0145 family
EPKFIKFJ_01180 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKFIKFJ_01181 5.59e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
EPKFIKFJ_01182 2.3e-76 yhjD - - - - - - -
EPKFIKFJ_01183 8.02e-136 yhjE - - S - - - SNARE associated Golgi protein
EPKFIKFJ_01184 1.3e-116 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPKFIKFJ_01185 0.0 yhjG - - CH - - - FAD binding domain
EPKFIKFJ_01186 9.88e-120 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_01187 2.03e-254 yhjN - - S ko:K07120 - ko00000 membrane
EPKFIKFJ_01188 1.56e-260 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_01189 1.24e-138 - - - K - - - QacR-like protein, C-terminal region
EPKFIKFJ_01190 3.47e-108 yhjR - - S - - - Rubrerythrin
EPKFIKFJ_01191 8.81e-152 ydfS - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_01192 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
EPKFIKFJ_01193 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
EPKFIKFJ_01194 7.47e-280 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EPKFIKFJ_01195 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
EPKFIKFJ_01196 3.36e-66 yisB - - V - - - COG1403 Restriction endonuclease
EPKFIKFJ_01197 5.49e-42 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
EPKFIKFJ_01198 2.37e-77 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
EPKFIKFJ_01199 1.44e-31 gerPD - - S ko:K06302 - ko00000 Spore germination protein
EPKFIKFJ_01200 3.28e-104 gerPC - - S ko:K06301 - ko00000 Spore germination protein
EPKFIKFJ_01201 5.87e-44 gerPB - - S ko:K06300 - ko00000 cell differentiation
EPKFIKFJ_01202 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
EPKFIKFJ_01203 2.45e-13 yisI - - S - - - Spo0E like sporulation regulatory protein
EPKFIKFJ_01204 2.25e-211 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
EPKFIKFJ_01205 4.48e-78 yisL - - S - - - UPF0344 protein
EPKFIKFJ_01206 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKFIKFJ_01207 5.25e-115 yisN - - S - - - Protein of unknown function (DUF2777)
EPKFIKFJ_01208 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EPKFIKFJ_01209 6.09e-150 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
EPKFIKFJ_01210 1.69e-307 yisQ - - V - - - Mate efflux family protein
EPKFIKFJ_01211 1.77e-201 yisR - - K - - - Transcriptional regulator
EPKFIKFJ_01212 3.87e-179 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
EPKFIKFJ_01213 2.32e-195 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
EPKFIKFJ_01214 3.26e-100 yisT - - S - - - DinB family
EPKFIKFJ_01215 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
EPKFIKFJ_01216 1.72e-232 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKFIKFJ_01217 9.1e-82 yisX - - S - - - Pentapeptide repeats (9 copies)
EPKFIKFJ_01218 6.78e-100 - - - S - - - Acetyltransferase (GNAT) domain
EPKFIKFJ_01219 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
EPKFIKFJ_01220 7.44e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
EPKFIKFJ_01221 3.3e-199 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
EPKFIKFJ_01222 2.3e-186 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
EPKFIKFJ_01223 1.06e-288 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
EPKFIKFJ_01224 4.22e-293 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
EPKFIKFJ_01225 8.05e-196 yitS - - S - - - protein conserved in bacteria
EPKFIKFJ_01226 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKFIKFJ_01227 5.07e-103 ipi - - S - - - Intracellular proteinase inhibitor
EPKFIKFJ_01228 4.3e-36 - - - S - - - Protein of unknown function (DUF3813)
EPKFIKFJ_01229 1.49e-11 - - - - - - - -
EPKFIKFJ_01230 3.84e-192 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
EPKFIKFJ_01231 1.98e-182 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EPKFIKFJ_01232 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
EPKFIKFJ_01233 3.29e-92 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
EPKFIKFJ_01234 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
EPKFIKFJ_01235 4.44e-117 yitZ - - G - - - Major Facilitator Superfamily
EPKFIKFJ_01236 4.41e-247 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPKFIKFJ_01237 4.35e-282 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EPKFIKFJ_01238 3.58e-166 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
EPKFIKFJ_01239 5.32e-266 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
EPKFIKFJ_01240 4.59e-248 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EPKFIKFJ_01241 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
EPKFIKFJ_01242 1.78e-220 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPKFIKFJ_01243 2.07e-38 yjzC - - S - - - YjzC-like protein
EPKFIKFJ_01244 3.71e-31 yjzD - - S - - - Protein of unknown function (DUF2929)
EPKFIKFJ_01245 6.59e-171 yjaU - - I - - - carboxylic ester hydrolase activity
EPKFIKFJ_01246 7.04e-127 yjaV - - - - - - -
EPKFIKFJ_01247 8.66e-209 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
EPKFIKFJ_01248 3.74e-36 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
EPKFIKFJ_01249 1.46e-37 yjzB - - - - - - -
EPKFIKFJ_01250 1.26e-218 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPKFIKFJ_01251 1.24e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EPKFIKFJ_01252 2.47e-179 yjaZ - - O - - - Zn-dependent protease
EPKFIKFJ_01253 1.81e-226 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01254 4.48e-232 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01255 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
EPKFIKFJ_01256 8.55e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKFIKFJ_01257 7.81e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKFIKFJ_01258 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
EPKFIKFJ_01259 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
EPKFIKFJ_01260 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EPKFIKFJ_01261 2.08e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKFIKFJ_01262 1.46e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKFIKFJ_01263 1.96e-252 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01264 1e-216 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01265 3.04e-280 - - - S - - - Putative glycosyl hydrolase domain
EPKFIKFJ_01266 1.04e-130 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKFIKFJ_01267 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EPKFIKFJ_01268 2.28e-140 yjbE - - P - - - Integral membrane protein TerC family
EPKFIKFJ_01269 2.3e-148 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EPKFIKFJ_01270 1.14e-256 coiA - - S ko:K06198 - ko00000 Competence protein
EPKFIKFJ_01271 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
EPKFIKFJ_01272 3.14e-27 - - - - - - - -
EPKFIKFJ_01273 9.23e-215 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EPKFIKFJ_01274 6.79e-91 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
EPKFIKFJ_01275 1.15e-138 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPKFIKFJ_01276 8.1e-118 yjbK - - S - - - protein conserved in bacteria
EPKFIKFJ_01277 3.37e-79 yjbL - - S - - - Belongs to the UPF0738 family
EPKFIKFJ_01278 3.67e-138 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
EPKFIKFJ_01279 6.92e-193 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPKFIKFJ_01280 2.7e-201 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
EPKFIKFJ_01281 1.1e-176 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
EPKFIKFJ_01282 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EPKFIKFJ_01283 2.06e-170 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EPKFIKFJ_01284 2.91e-132 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
EPKFIKFJ_01285 8.33e-255 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
EPKFIKFJ_01286 5.3e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
EPKFIKFJ_01287 1.81e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EPKFIKFJ_01288 7.09e-228 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EPKFIKFJ_01289 2.99e-180 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EPKFIKFJ_01290 1.38e-179 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
EPKFIKFJ_01291 2.47e-100 yjbX - - S - - - Spore coat protein
EPKFIKFJ_01292 3.35e-105 cotZ - - S ko:K06344 - ko00000 Spore coat protein
EPKFIKFJ_01293 1.75e-120 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
EPKFIKFJ_01294 3.55e-98 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
EPKFIKFJ_01295 1.02e-36 cotW - - - ko:K06341 - ko00000 -
EPKFIKFJ_01296 4.61e-69 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
EPKFIKFJ_01297 1.69e-72 yjcA - - S - - - Protein of unknown function (DUF1360)
EPKFIKFJ_01300 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EPKFIKFJ_01301 1.05e-50 spoVIF - - S - - - Stage VI sporulation protein F
EPKFIKFJ_01302 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKFIKFJ_01303 1.62e-44 - - - - - - - -
EPKFIKFJ_01304 6.53e-167 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
EPKFIKFJ_01305 2e-154 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EPKFIKFJ_01306 1.09e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
EPKFIKFJ_01307 1.19e-45 - - - K - - - SpoVT / AbrB like domain
EPKFIKFJ_01308 6.83e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKFIKFJ_01309 6.7e-119 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
EPKFIKFJ_01310 1.79e-157 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
EPKFIKFJ_01311 2.09e-266 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPKFIKFJ_01312 5.84e-273 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPKFIKFJ_01314 2.36e-99 - - - L - - - Belongs to the 'phage' integrase family
EPKFIKFJ_01319 1.92e-180 - - - S - - - N-methyltransferase activity
EPKFIKFJ_01324 1.05e-278 - - - - - - - -
EPKFIKFJ_01328 1.73e-40 - - - - - - - -
EPKFIKFJ_01329 2.02e-47 - - - - - - - -
EPKFIKFJ_01330 2.19e-80 - - - - - - - -
EPKFIKFJ_01333 1.19e-29 - - - - - - - -
EPKFIKFJ_01335 4.7e-20 - - - K - - - Transcriptional regulator
EPKFIKFJ_01336 8.97e-68 - - - S - - - Helix-turn-helix of insertion element transposase
EPKFIKFJ_01337 2.33e-97 - - - L - - - Resolvase, N terminal domain
EPKFIKFJ_01338 0.0 - - - S - - - TIGRFAM Phage
EPKFIKFJ_01339 5.61e-207 - - - S - - - Phage portal protein, SPP1 Gp6-like
EPKFIKFJ_01340 7.64e-76 - - - S - - - Domain of unknown function (DUF4355)
EPKFIKFJ_01341 1.16e-114 - - - S - - - P22 coat protein-protein 5 domain protein
EPKFIKFJ_01345 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPKFIKFJ_01349 1.49e-11 - - - - - - - -
EPKFIKFJ_01350 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
EPKFIKFJ_01351 8.54e-309 - - - I - - - Pfam Lipase (class 3)
EPKFIKFJ_01352 1.06e-54 - - - - - - - -
EPKFIKFJ_01354 1.71e-30 - - - K - - - Cro/C1-type HTH DNA-binding domain
EPKFIKFJ_01359 2.89e-73 - - - - - - - -
EPKFIKFJ_01360 2.31e-90 - - - S - - - Bacterial EndoU nuclease
EPKFIKFJ_01361 1.06e-42 - - - - - - - -
EPKFIKFJ_01362 1.86e-116 yokH - - G - - - SMI1 / KNR4 family
EPKFIKFJ_01363 1.61e-128 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 2-dehydropantoate 2-reductase
EPKFIKFJ_01364 2.21e-28 yokK - - S - - - SMI1 / KNR4 family
EPKFIKFJ_01365 9.5e-81 - - - H - - - Acetyltransferase (GNAT) domain
EPKFIKFJ_01367 1.06e-247 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM Reverse transcriptase (RNA-dependent DNA polymerase)
EPKFIKFJ_01368 7.99e-240 - - - K - - - Psort location Cytoplasmic, score
EPKFIKFJ_01369 2.8e-119 - - - K - - - Psort location Cytoplasmic, score
EPKFIKFJ_01370 3.84e-226 - - - K - - - Psort location Cytoplasmic, score
EPKFIKFJ_01371 5.83e-10 - - - - - - - -
EPKFIKFJ_01372 9.18e-49 - - - S - - - YolD-like protein
EPKFIKFJ_01373 2.46e-57 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPKFIKFJ_01374 4.74e-38 - - - S - - - Bacillus cereus group antimicrobial protein
EPKFIKFJ_01378 0.000667 KLHL36 - - T ko:K13958 - ko00000,ko04121 protein modification by small protein conjugation
EPKFIKFJ_01379 4.57e-21 - - - N - - - Kelch motif
EPKFIKFJ_01381 3.78e-196 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
EPKFIKFJ_01382 7.1e-58 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
EPKFIKFJ_01383 5.5e-302 yfjF - - EGP - - - Belongs to the major facilitator superfamily
EPKFIKFJ_01384 1.09e-99 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_01385 7.71e-277 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
EPKFIKFJ_01386 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPKFIKFJ_01387 3.63e-66 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_01388 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKFIKFJ_01389 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EPKFIKFJ_01390 1.67e-151 - - - S - - - Haloacid dehalogenase-like hydrolase
EPKFIKFJ_01391 3.81e-45 - - - - - - - -
EPKFIKFJ_01392 4.16e-69 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_01393 2.77e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
EPKFIKFJ_01395 1.07e-28 yjfB - - S - - - Putative motility protein
EPKFIKFJ_01396 6.25e-83 yjgA - - T - - - Protein of unknown function (DUF2809)
EPKFIKFJ_01397 4.05e-122 yjgB - - S - - - Domain of unknown function (DUF4309)
EPKFIKFJ_01398 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
EPKFIKFJ_01399 3.47e-150 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
EPKFIKFJ_01400 1.44e-180 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EPKFIKFJ_01401 1.73e-40 - - - - - - - -
EPKFIKFJ_01402 3.96e-275 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
EPKFIKFJ_01403 1.09e-273 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKFIKFJ_01404 5.21e-88 yjgD - - S - - - Protein of unknown function (DUF1641)
EPKFIKFJ_01405 8.89e-184 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
EPKFIKFJ_01406 4.94e-42 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01407 5.99e-220 yjlA - - EG - - - Putative multidrug resistance efflux transporter
EPKFIKFJ_01408 1.47e-110 yjlB - - S - - - Cupin domain
EPKFIKFJ_01409 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
EPKFIKFJ_01410 8.37e-278 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EPKFIKFJ_01411 2.92e-80 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
EPKFIKFJ_01412 3.99e-232 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
EPKFIKFJ_01413 3.18e-203 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
EPKFIKFJ_01414 1.29e-112 - - - T - - - Transcriptional regulatory protein, C terminal
EPKFIKFJ_01415 2.12e-165 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
EPKFIKFJ_01417 7.24e-164 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
EPKFIKFJ_01418 9.4e-100 yjoA - - S - - - DinB family
EPKFIKFJ_01419 3.13e-274 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKFIKFJ_01421 5.72e-213 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_01422 3.19e-79 yjqA - - S - - - Bacterial PH domain
EPKFIKFJ_01423 2.69e-128 yjqB - - S - - - phage-related replication protein
EPKFIKFJ_01424 2.86e-139 xkdA - - E - - - IrrE N-terminal-like domain
EPKFIKFJ_01425 1.27e-72 xre - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_01427 8.33e-185 xkdC - - L - - - Bacterial dnaA protein
EPKFIKFJ_01431 3.15e-105 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
EPKFIKFJ_01432 1.37e-139 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
EPKFIKFJ_01433 3.35e-263 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
EPKFIKFJ_01434 1.72e-302 xkdE3 - - S - - - portal protein
EPKFIKFJ_01435 8.47e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
EPKFIKFJ_01436 3.38e-202 xkdG - - S - - - Phage capsid family
EPKFIKFJ_01438 2.41e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
EPKFIKFJ_01439 1.82e-75 xkdJ - - - - - - -
EPKFIKFJ_01440 3.86e-21 - - - - - - - -
EPKFIKFJ_01441 4.44e-285 xkdK - - S - - - Phage tail sheath C-terminal domain
EPKFIKFJ_01442 8.21e-97 xkdM - - S - - - Phage tail tube protein
EPKFIKFJ_01443 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
EPKFIKFJ_01444 4.33e-27 - - - - - - - -
EPKFIKFJ_01445 7.01e-277 xkdO - - L - - - Transglycosylase SLT domain
EPKFIKFJ_01446 1.88e-144 xkdP - - S - - - Lysin motif
EPKFIKFJ_01447 2.78e-208 xkdQ - - G - - - NLP P60 protein
EPKFIKFJ_01448 3.05e-44 xkdR - - S - - - Protein of unknown function (DUF2577)
EPKFIKFJ_01449 2.35e-75 xkdS - - S - - - Protein of unknown function (DUF2634)
EPKFIKFJ_01450 7.44e-208 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
EPKFIKFJ_01451 3.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
EPKFIKFJ_01452 1.48e-36 - - - - - - - -
EPKFIKFJ_01453 1.18e-193 - - - - - - - -
EPKFIKFJ_01455 1.05e-36 xkdX - - - - - - -
EPKFIKFJ_01456 2.97e-167 xepA - - - - - - -
EPKFIKFJ_01457 6.44e-50 xhlA - - S - - - Haemolysin XhlA
EPKFIKFJ_01458 2.62e-49 xhlB - - S - - - SPP1 phage holin
EPKFIKFJ_01459 9.72e-183 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_01460 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
EPKFIKFJ_01461 1.05e-169 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
EPKFIKFJ_01462 2.36e-224 pit - - P ko:K03306 - ko00000 phosphate transporter
EPKFIKFJ_01463 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
EPKFIKFJ_01464 2.11e-308 steT - - E ko:K03294 - ko00000 amino acid
EPKFIKFJ_01465 1.75e-227 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EPKFIKFJ_01466 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPKFIKFJ_01467 3.02e-227 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKFIKFJ_01469 2.08e-266 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKFIKFJ_01470 0.0 yubD - - P - - - Major Facilitator Superfamily
EPKFIKFJ_01471 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
EPKFIKFJ_01472 2.68e-202 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKFIKFJ_01473 3.22e-218 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EPKFIKFJ_01474 1.49e-230 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01475 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EPKFIKFJ_01476 8.59e-221 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
EPKFIKFJ_01477 2e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
EPKFIKFJ_01478 1.74e-198 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EPKFIKFJ_01479 1.49e-227 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_01480 6.11e-256 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
EPKFIKFJ_01481 1.45e-179 ykgA - - E - - - Amidinotransferase
EPKFIKFJ_01482 2.16e-120 ykhA - - I - - - Acyl-CoA hydrolase
EPKFIKFJ_01483 1.01e-118 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
EPKFIKFJ_01484 8.24e-64 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
EPKFIKFJ_01485 1.22e-64 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
EPKFIKFJ_01486 1.03e-211 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
EPKFIKFJ_01487 3.28e-257 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPKFIKFJ_01488 1.35e-281 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPKFIKFJ_01489 1.89e-90 ohrA - - O - - - Organic hydroperoxide resistance protein
EPKFIKFJ_01490 6.88e-102 ohrR - - K - - - COG1846 Transcriptional regulators
EPKFIKFJ_01491 1.3e-90 ohrB - - O - - - Organic hydroperoxide resistance protein
EPKFIKFJ_01492 1.46e-70 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EPKFIKFJ_01494 2.15e-260 - - - M - - - Glycosyl transferase family 2
EPKFIKFJ_01495 8.96e-151 - - - K - - - Collagen triple helix repeat
EPKFIKFJ_01496 5.93e-263 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_01497 7.17e-152 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EPKFIKFJ_01498 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPKFIKFJ_01499 2.76e-221 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKFIKFJ_01500 2.08e-179 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKFIKFJ_01501 7.49e-161 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
EPKFIKFJ_01502 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_01503 3.67e-123 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
EPKFIKFJ_01504 4.54e-303 ydhD - - M - - - Glycosyl hydrolase
EPKFIKFJ_01506 7.93e-306 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
EPKFIKFJ_01507 3.53e-69 tnrA - - K - - - transcriptional
EPKFIKFJ_01508 2.24e-23 - - - - - - - -
EPKFIKFJ_01509 3.57e-35 ykoL - - - - - - -
EPKFIKFJ_01510 3.16e-104 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
EPKFIKFJ_01511 2.57e-127 ykoP - - G - - - polysaccharide deacetylase
EPKFIKFJ_01512 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
EPKFIKFJ_01513 1.82e-197 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
EPKFIKFJ_01514 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
EPKFIKFJ_01515 1.21e-123 ykoX - - S - - - membrane-associated protein
EPKFIKFJ_01516 5.75e-164 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
EPKFIKFJ_01517 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKFIKFJ_01518 3.51e-221 ykrI - - S - - - Anti-sigma factor N-terminus
EPKFIKFJ_01519 3.31e-35 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
EPKFIKFJ_01520 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
EPKFIKFJ_01521 1.74e-197 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
EPKFIKFJ_01522 7.83e-301 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
EPKFIKFJ_01523 2.76e-144 - - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_01524 1.37e-26 ykzE - - - - - - -
EPKFIKFJ_01525 1.59e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
EPKFIKFJ_01526 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_01527 9.18e-105 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPKFIKFJ_01529 1.59e-244 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EPKFIKFJ_01530 9.79e-278 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
EPKFIKFJ_01531 1.03e-175 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EPKFIKFJ_01532 1.52e-283 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPKFIKFJ_01533 4.16e-284 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
EPKFIKFJ_01534 1.45e-169 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
EPKFIKFJ_01535 1.15e-140 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
EPKFIKFJ_01536 7.7e-117 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EPKFIKFJ_01538 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EPKFIKFJ_01539 3.34e-101 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
EPKFIKFJ_01540 2.49e-160 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EPKFIKFJ_01541 2.96e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EPKFIKFJ_01542 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
EPKFIKFJ_01543 6.18e-222 ykvI - - S - - - membrane
EPKFIKFJ_01545 3.65e-196 - - - - - - - -
EPKFIKFJ_01546 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EPKFIKFJ_01547 2.55e-102 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
EPKFIKFJ_01548 1.98e-176 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EPKFIKFJ_01549 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EPKFIKFJ_01550 6.76e-56 ykvR - - S - - - Protein of unknown function (DUF3219)
EPKFIKFJ_01551 1.56e-34 ykvS - - S - - - protein conserved in bacteria
EPKFIKFJ_01552 8.76e-38 - - - - - - - -
EPKFIKFJ_01553 5.23e-136 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
EPKFIKFJ_01554 3.31e-300 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKFIKFJ_01555 1.04e-105 stoA - - CO - - - thiol-disulfide
EPKFIKFJ_01556 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EPKFIKFJ_01557 1.51e-259 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EPKFIKFJ_01559 4.21e-217 ykvZ - - K - - - Transcriptional regulator
EPKFIKFJ_01560 1.54e-196 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
EPKFIKFJ_01561 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_01562 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
EPKFIKFJ_01563 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPKFIKFJ_01564 1.22e-48 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_01565 2.29e-252 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
EPKFIKFJ_01566 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKFIKFJ_01567 5.71e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
EPKFIKFJ_01568 9.19e-65 - - - - - - - -
EPKFIKFJ_01569 1.7e-167 ykwD - - J - - - protein with SCP PR1 domains
EPKFIKFJ_01570 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EPKFIKFJ_01571 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_01572 5.43e-274 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
EPKFIKFJ_01573 2.22e-15 - - - - - - - -
EPKFIKFJ_01574 1.3e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
EPKFIKFJ_01575 1.45e-107 ykyB - - S - - - YkyB-like protein
EPKFIKFJ_01576 2e-302 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_01577 3.48e-114 ykuD - - S - - - protein conserved in bacteria
EPKFIKFJ_01578 7.29e-188 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
EPKFIKFJ_01579 1.33e-175 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_01581 1.74e-293 ykuI - - T - - - Diguanylate phosphodiesterase
EPKFIKFJ_01582 2.11e-49 ykuJ - - S - - - protein conserved in bacteria
EPKFIKFJ_01583 6.94e-117 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
EPKFIKFJ_01584 2.63e-36 ykzF - - S - - - Antirepressor AbbA
EPKFIKFJ_01585 7.03e-98 ykuL - - S - - - CBS domain
EPKFIKFJ_01586 1.08e-214 ccpC - - K - - - Transcriptional regulator
EPKFIKFJ_01587 2.92e-113 ykuN - - C ko:K03839 - ko00000 Flavodoxin
EPKFIKFJ_01588 1.07e-207 ykuO - - - - - - -
EPKFIKFJ_01589 2.61e-95 fld - - C ko:K03839 - ko00000 Flavodoxin
EPKFIKFJ_01590 4.79e-128 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EPKFIKFJ_01591 8.58e-271 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EPKFIKFJ_01592 1.25e-51 ykuS - - S - - - Belongs to the UPF0180 family
EPKFIKFJ_01593 5.77e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
EPKFIKFJ_01595 1.9e-93 ykuV - - CO - - - thiol-disulfide
EPKFIKFJ_01597 3.55e-125 rok - - K - - - Repressor of ComK
EPKFIKFJ_01598 1.69e-200 yknT - - - ko:K06437 - ko00000 -
EPKFIKFJ_01599 3.85e-130 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EPKFIKFJ_01600 1.45e-233 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EPKFIKFJ_01601 7.3e-305 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
EPKFIKFJ_01602 3.06e-111 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
EPKFIKFJ_01603 1.19e-107 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
EPKFIKFJ_01604 4.7e-43 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EPKFIKFJ_01605 5.77e-134 yknW - - S - - - Yip1 domain
EPKFIKFJ_01606 7e-224 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPKFIKFJ_01607 3.39e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_01608 4.52e-264 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
EPKFIKFJ_01609 8.9e-168 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_01610 8.8e-210 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
EPKFIKFJ_01611 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
EPKFIKFJ_01612 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPKFIKFJ_01613 3.54e-48 ykoA - - - - - - -
EPKFIKFJ_01614 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
EPKFIKFJ_01615 7.33e-145 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPKFIKFJ_01616 1.38e-28 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPKFIKFJ_01617 1.63e-300 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
EPKFIKFJ_01618 7.7e-19 - - - S - - - Uncharacterized protein YkpC
EPKFIKFJ_01619 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
EPKFIKFJ_01620 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
EPKFIKFJ_01621 9.16e-301 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EPKFIKFJ_01622 3.99e-192 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
EPKFIKFJ_01623 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EPKFIKFJ_01624 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EPKFIKFJ_01625 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPKFIKFJ_01626 7.4e-41 ykzG - - S - - - Belongs to the UPF0356 family
EPKFIKFJ_01627 3.14e-180 ykrA - - S - - - hydrolases of the HAD superfamily
EPKFIKFJ_01628 1.49e-126 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPKFIKFJ_01629 1.04e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EPKFIKFJ_01630 9.3e-84 ykyA - - L - - - Putative cell-wall binding lipoprotein
EPKFIKFJ_01631 1.04e-249 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPKFIKFJ_01632 5.84e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPKFIKFJ_01633 6.09e-294 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPKFIKFJ_01634 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPKFIKFJ_01635 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
EPKFIKFJ_01636 3.33e-173 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EPKFIKFJ_01637 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
EPKFIKFJ_01638 5.44e-56 yktA - - S - - - Belongs to the UPF0223 family
EPKFIKFJ_01639 4.72e-154 yktB - - S - - - Belongs to the UPF0637 family
EPKFIKFJ_01640 7.89e-32 ykzI - - - - - - -
EPKFIKFJ_01641 1.57e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
EPKFIKFJ_01642 1.08e-92 ykzC - - S - - - Acetyltransferase (GNAT) family
EPKFIKFJ_01643 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
EPKFIKFJ_01644 9.3e-32 ylaA - - - - - - -
EPKFIKFJ_01646 1.97e-52 ylaE - - - - - - -
EPKFIKFJ_01647 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
EPKFIKFJ_01648 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
EPKFIKFJ_01649 1.41e-64 - - - S - - - YlaH-like protein
EPKFIKFJ_01650 7.95e-45 ylaI - - S - - - protein conserved in bacteria
EPKFIKFJ_01651 2.67e-129 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKFIKFJ_01652 4.29e-310 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
EPKFIKFJ_01653 4.45e-104 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EPKFIKFJ_01654 6.76e-217 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
EPKFIKFJ_01655 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
EPKFIKFJ_01656 3.73e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EPKFIKFJ_01657 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
EPKFIKFJ_01658 3.88e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
EPKFIKFJ_01659 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
EPKFIKFJ_01660 2.78e-251 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
EPKFIKFJ_01661 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPKFIKFJ_01662 3.43e-141 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
EPKFIKFJ_01663 2.04e-68 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
EPKFIKFJ_01664 1.35e-207 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
EPKFIKFJ_01665 8.01e-77 ylbA - - S - - - YugN-like family
EPKFIKFJ_01666 1.31e-93 ylbB - - T - - - COG0517 FOG CBS domain
EPKFIKFJ_01667 5.8e-248 ylbC - - S - - - protein with SCP PR1 domains
EPKFIKFJ_01668 5.5e-83 ylbD - - S - - - Putative coat protein
EPKFIKFJ_01669 1.73e-48 ylbE - - S - - - YlbE-like protein
EPKFIKFJ_01670 3.73e-94 ylbF - - S - - - Belongs to the UPF0342 family
EPKFIKFJ_01671 4.62e-56 ylbG - - S - - - UPF0298 protein
EPKFIKFJ_01672 4.27e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
EPKFIKFJ_01673 2.38e-109 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPKFIKFJ_01674 8.16e-268 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
EPKFIKFJ_01675 2.03e-177 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EPKFIKFJ_01676 7.74e-234 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
EPKFIKFJ_01677 1.26e-281 ylbM - - S - - - Belongs to the UPF0348 family
EPKFIKFJ_01678 4.69e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
EPKFIKFJ_01679 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
EPKFIKFJ_01680 1.65e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
EPKFIKFJ_01681 2.68e-115 ylbP - - K - - - n-acetyltransferase
EPKFIKFJ_01682 1.28e-189 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPKFIKFJ_01683 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
EPKFIKFJ_01684 9.07e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
EPKFIKFJ_01685 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPKFIKFJ_01686 2.81e-67 ftsL - - D - - - Essential cell division protein
EPKFIKFJ_01687 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
EPKFIKFJ_01688 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
EPKFIKFJ_01689 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPKFIKFJ_01690 2.36e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPKFIKFJ_01691 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPKFIKFJ_01692 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EPKFIKFJ_01693 3.84e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPKFIKFJ_01694 3.07e-210 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
EPKFIKFJ_01695 3.74e-170 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EPKFIKFJ_01696 3.7e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EPKFIKFJ_01697 4.32e-259 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPKFIKFJ_01698 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
EPKFIKFJ_01699 2.17e-213 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
EPKFIKFJ_01700 3.64e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKFIKFJ_01701 3.8e-178 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKFIKFJ_01702 2.58e-183 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
EPKFIKFJ_01703 1.67e-308 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
EPKFIKFJ_01704 7.13e-52 ylmC - - S - - - sporulation protein
EPKFIKFJ_01705 3.85e-196 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
EPKFIKFJ_01706 6.55e-155 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPKFIKFJ_01707 8.91e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPKFIKFJ_01708 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
EPKFIKFJ_01709 3.8e-176 ylmH - - S - - - conserved protein, contains S4-like domain
EPKFIKFJ_01710 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
EPKFIKFJ_01711 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPKFIKFJ_01712 4.22e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
EPKFIKFJ_01713 8.42e-102 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPKFIKFJ_01714 7.29e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
EPKFIKFJ_01715 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPKFIKFJ_01716 8.98e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
EPKFIKFJ_01717 2.06e-204 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
EPKFIKFJ_01718 1.67e-309 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPKFIKFJ_01719 4.71e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
EPKFIKFJ_01720 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
EPKFIKFJ_01721 2.68e-176 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EPKFIKFJ_01722 1.17e-218 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPKFIKFJ_01723 2.37e-159 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EPKFIKFJ_01724 3.5e-146 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPKFIKFJ_01725 7.81e-178 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
EPKFIKFJ_01726 5.26e-223 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
EPKFIKFJ_01727 5.92e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
EPKFIKFJ_01728 1.31e-140 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
EPKFIKFJ_01729 7.4e-179 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
EPKFIKFJ_01730 1.13e-175 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
EPKFIKFJ_01731 1.85e-98 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
EPKFIKFJ_01732 0.0 - 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
EPKFIKFJ_01733 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
EPKFIKFJ_01734 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
EPKFIKFJ_01735 8e-194 yloC - - S - - - stress-induced protein
EPKFIKFJ_01736 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
EPKFIKFJ_01737 1.16e-142 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
EPKFIKFJ_01738 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPKFIKFJ_01739 2e-283 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPKFIKFJ_01740 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPKFIKFJ_01741 1.61e-107 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPKFIKFJ_01742 6.66e-215 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPKFIKFJ_01743 5.67e-313 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPKFIKFJ_01744 7.22e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EPKFIKFJ_01745 4.92e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
EPKFIKFJ_01746 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
EPKFIKFJ_01747 6.97e-208 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EPKFIKFJ_01748 4.85e-148 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
EPKFIKFJ_01749 5.45e-146 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
EPKFIKFJ_01750 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
EPKFIKFJ_01751 6.07e-77 yloU - - S - - - protein conserved in bacteria
EPKFIKFJ_01752 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
EPKFIKFJ_01753 1.69e-152 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EPKFIKFJ_01754 3.97e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
EPKFIKFJ_01755 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPKFIKFJ_01756 2.96e-119 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
EPKFIKFJ_01757 2.58e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EPKFIKFJ_01758 2.08e-215 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EPKFIKFJ_01759 5.81e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
EPKFIKFJ_01760 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPKFIKFJ_01761 2.48e-173 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPKFIKFJ_01762 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
EPKFIKFJ_01763 2.09e-221 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPKFIKFJ_01764 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EPKFIKFJ_01765 2e-301 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPKFIKFJ_01766 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
EPKFIKFJ_01767 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
EPKFIKFJ_01768 5.66e-79 ylqD - - S - - - YlqD protein
EPKFIKFJ_01769 4.17e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPKFIKFJ_01770 2.22e-173 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
EPKFIKFJ_01771 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPKFIKFJ_01772 5.95e-202 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPKFIKFJ_01773 1.87e-171 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPKFIKFJ_01774 0.0 ylqG - - - - - - -
EPKFIKFJ_01775 6.68e-57 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
EPKFIKFJ_01776 1.66e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EPKFIKFJ_01777 2.17e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPKFIKFJ_01778 6.19e-208 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
EPKFIKFJ_01779 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPKFIKFJ_01780 1.05e-311 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EPKFIKFJ_01781 1.42e-216 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
EPKFIKFJ_01782 1.43e-118 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EPKFIKFJ_01783 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EPKFIKFJ_01784 7.94e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EPKFIKFJ_01785 3.14e-81 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
EPKFIKFJ_01786 1.46e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
EPKFIKFJ_01787 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
EPKFIKFJ_01788 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
EPKFIKFJ_01789 3.52e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EPKFIKFJ_01790 6.92e-116 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
EPKFIKFJ_01791 2.02e-306 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
EPKFIKFJ_01792 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
EPKFIKFJ_01793 3.78e-76 ylxF - - S - - - MgtE intracellular N domain
EPKFIKFJ_01794 7.87e-242 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
EPKFIKFJ_01795 2.43e-90 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
EPKFIKFJ_01796 2.56e-175 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
EPKFIKFJ_01797 3.66e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
EPKFIKFJ_01798 1.28e-228 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
EPKFIKFJ_01799 9.42e-231 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EPKFIKFJ_01800 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
EPKFIKFJ_01801 6.3e-142 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
EPKFIKFJ_01802 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
EPKFIKFJ_01803 9.02e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
EPKFIKFJ_01804 4.51e-165 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
EPKFIKFJ_01805 3.29e-238 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPKFIKFJ_01806 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EPKFIKFJ_01807 4.59e-210 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
EPKFIKFJ_01808 1.43e-196 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
EPKFIKFJ_01809 2.82e-239 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
EPKFIKFJ_01810 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
EPKFIKFJ_01811 1.01e-104 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
EPKFIKFJ_01812 1.39e-141 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
EPKFIKFJ_01813 6.74e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
EPKFIKFJ_01814 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKFIKFJ_01815 2.54e-84 ylxL - - - - - - -
EPKFIKFJ_01816 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
EPKFIKFJ_01817 4.66e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPKFIKFJ_01818 2.03e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
EPKFIKFJ_01819 1.59e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPKFIKFJ_01820 2.49e-183 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPKFIKFJ_01821 1.48e-176 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
EPKFIKFJ_01822 8.59e-271 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EPKFIKFJ_01823 2.58e-293 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
EPKFIKFJ_01824 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPKFIKFJ_01825 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPKFIKFJ_01826 9.4e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
EPKFIKFJ_01827 1.35e-262 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
EPKFIKFJ_01828 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
EPKFIKFJ_01829 6.16e-63 ylxQ - - J - - - ribosomal protein
EPKFIKFJ_01830 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPKFIKFJ_01831 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
EPKFIKFJ_01832 2.38e-67 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPKFIKFJ_01833 2.64e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPKFIKFJ_01834 6.31e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
EPKFIKFJ_01835 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPKFIKFJ_01836 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EPKFIKFJ_01837 2.3e-229 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
EPKFIKFJ_01838 9.79e-298 mlpA - - S - - - Belongs to the peptidase M16 family
EPKFIKFJ_01839 2.17e-56 ymxH - - S - - - YlmC YmxH family
EPKFIKFJ_01840 4.32e-202 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
EPKFIKFJ_01841 6.97e-131 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
EPKFIKFJ_01842 5.33e-244 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPKFIKFJ_01843 3.69e-278 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPKFIKFJ_01844 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPKFIKFJ_01845 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPKFIKFJ_01846 5.34e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
EPKFIKFJ_01847 7.4e-41 - - - S - - - YlzJ-like protein
EPKFIKFJ_01848 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EPKFIKFJ_01849 1.38e-166 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_01850 2.76e-290 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_01851 7.8e-97 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_01852 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
EPKFIKFJ_01853 8.12e-300 albE - - S - - - Peptidase M16
EPKFIKFJ_01854 2.09e-303 ymfH - - S - - - zinc protease
EPKFIKFJ_01855 1.13e-161 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
EPKFIKFJ_01856 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
EPKFIKFJ_01857 3.66e-182 ymfK - - S - - - Protein of unknown function (DUF3388)
EPKFIKFJ_01858 2.26e-166 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
EPKFIKFJ_01859 2.75e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPKFIKFJ_01860 2.57e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
EPKFIKFJ_01861 8.4e-237 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPKFIKFJ_01862 4.31e-260 pbpX - - V - - - Beta-lactamase
EPKFIKFJ_01863 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
EPKFIKFJ_01864 3.06e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
EPKFIKFJ_01865 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
EPKFIKFJ_01866 1.32e-247 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
EPKFIKFJ_01867 2.28e-270 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EPKFIKFJ_01868 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EPKFIKFJ_01869 2.37e-85 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
EPKFIKFJ_01870 3.93e-116 cotE - - S ko:K06328 - ko00000 Spore coat protein
EPKFIKFJ_01871 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPKFIKFJ_01872 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EPKFIKFJ_01873 3.58e-160 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
EPKFIKFJ_01874 1.77e-202 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EPKFIKFJ_01875 7.96e-188 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
EPKFIKFJ_01876 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EPKFIKFJ_01877 6.16e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
EPKFIKFJ_01878 9.98e-307 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
EPKFIKFJ_01879 7.4e-179 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
EPKFIKFJ_01880 6.35e-176 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
EPKFIKFJ_01881 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EPKFIKFJ_01882 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EPKFIKFJ_01883 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
EPKFIKFJ_01884 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
EPKFIKFJ_01885 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
EPKFIKFJ_01886 4.53e-283 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKFIKFJ_01887 3e-93 nucB - - M - - - Deoxyribonuclease NucA/NucB
EPKFIKFJ_01888 3.52e-149 yoaK - - S - - - Membrane
EPKFIKFJ_01889 9.32e-81 ymzB - - - - - - -
EPKFIKFJ_01890 9.4e-317 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
EPKFIKFJ_01891 2.64e-07 - - - - - - - -
EPKFIKFJ_01892 3.08e-151 ymaC - - S - - - Replication protein
EPKFIKFJ_01893 9.17e-100 ymaD - - O - - - redox protein, regulator of disulfide bond formation
EPKFIKFJ_01894 1.76e-70 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EPKFIKFJ_01895 1.17e-62 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
EPKFIKFJ_01897 9.08e-72 ymaF - - S - - - YmaF family
EPKFIKFJ_01898 7.19e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPKFIKFJ_01899 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
EPKFIKFJ_01900 1.87e-53 - - - - - - - -
EPKFIKFJ_01901 2.31e-29 ymzA - - - - - - -
EPKFIKFJ_01902 4.43e-77 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
EPKFIKFJ_01903 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPKFIKFJ_01904 5.94e-237 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPKFIKFJ_01905 2.21e-132 ymaB - - S - - - MutT family
EPKFIKFJ_01906 3.91e-05 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_01907 2e-112 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_01908 2.58e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
EPKFIKFJ_01909 9.64e-289 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPKFIKFJ_01910 5.35e-307 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
EPKFIKFJ_01911 8.18e-86 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
EPKFIKFJ_01912 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
EPKFIKFJ_01913 3.55e-170 - - - L - - - Belongs to the 'phage' integrase family
EPKFIKFJ_01914 6.53e-51 - - - CE - - - IrrE N-terminal-like domain
EPKFIKFJ_01915 1e-11 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 PFAM helix-turn-helix domain protein
EPKFIKFJ_01917 3.9e-60 - - - S ko:K07741 - ko00000 Phage regulatory protein Rha (Phage_pRha)
EPKFIKFJ_01921 1.54e-34 - - - - - - - -
EPKFIKFJ_01922 2.82e-16 - - - - - - - -
EPKFIKFJ_01923 4.71e-203 - - - L - - - Protein of unknown function (DUF2800)
EPKFIKFJ_01924 5.24e-111 - - - S - - - Protein of unknown function (DUF2815)
EPKFIKFJ_01925 1.89e-08 - - - - - - - -
EPKFIKFJ_01926 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase A domain
EPKFIKFJ_01928 2.23e-132 - 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EPKFIKFJ_01929 1.67e-15 - - - S - - - Protein of unknown function (DUF2815)
EPKFIKFJ_01930 0.0 - - - L - - - Virulence-associated protein E
EPKFIKFJ_01931 8.06e-27 - - - S - - - VRR_NUC
EPKFIKFJ_01932 3.74e-288 - - - KL - - - SNF2 family N-terminal domain
EPKFIKFJ_01933 4.27e-64 - - - - - - - -
EPKFIKFJ_01935 2.38e-74 - - - L - - - Terminase, small subunit
EPKFIKFJ_01936 6.45e-182 terL - - S - - - Terminase
EPKFIKFJ_01938 8.92e-222 - - - S - - - portal protein
EPKFIKFJ_01939 8.38e-96 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
EPKFIKFJ_01940 2.09e-161 - - - S - - - capsid protein
EPKFIKFJ_01941 8.87e-29 - - - - - - - -
EPKFIKFJ_01942 5.7e-11 - - - S - - - Phage gp6-like head-tail connector protein
EPKFIKFJ_01943 7.37e-41 - - - S - - - Phage head-tail joining protein
EPKFIKFJ_01944 1.03e-42 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EPKFIKFJ_01946 8.06e-43 - - - S - - - Phage tail tube protein
EPKFIKFJ_01948 0.0 - - - D - - - Phage tail tape measure protein
EPKFIKFJ_01949 1.62e-149 - - - S - - - Phage tail protein
EPKFIKFJ_01950 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
EPKFIKFJ_01951 0.0 - - - M - - - Pectate lyase superfamily protein
EPKFIKFJ_01952 2.8e-210 - - - S - - - Domain of unknown function (DUF2479)
EPKFIKFJ_01955 2.01e-79 - - - S - - - Pfam:Phage_holin_4_1
EPKFIKFJ_01956 5.35e-162 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_01957 6.36e-21 - - - S - - - Domain of unknown function (DUF4917)
EPKFIKFJ_01958 5.92e-12 - - - - - - - -
EPKFIKFJ_01961 6.66e-151 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EPKFIKFJ_01962 1.54e-271 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKFIKFJ_01963 8.41e-314 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
EPKFIKFJ_01964 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKFIKFJ_01965 1.91e-130 xylR - - GK - - - ROK family
EPKFIKFJ_01966 3.68e-93 xylR - - GK - - - ROK family
EPKFIKFJ_01967 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
EPKFIKFJ_01968 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
EPKFIKFJ_01969 4.44e-150 - 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
EPKFIKFJ_01970 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
EPKFIKFJ_01971 7.81e-116 - - - K - - - Transcriptional regulator, TetR family
EPKFIKFJ_01972 3.77e-225 bdhA 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
EPKFIKFJ_01974 1.8e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EPKFIKFJ_01975 0.000425 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EPKFIKFJ_01976 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
EPKFIKFJ_01977 2.84e-123 tnpR - - L - - - resolvase
EPKFIKFJ_01978 4.04e-103 - - - - - - - -
EPKFIKFJ_01980 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
EPKFIKFJ_01981 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKFIKFJ_01982 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EPKFIKFJ_01983 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EPKFIKFJ_01984 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
EPKFIKFJ_01985 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
EPKFIKFJ_01986 6.56e-192 - - - S - - - membrane
EPKFIKFJ_01987 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_01988 0.0 - - - I - - - PLD-like domain
EPKFIKFJ_01989 1.16e-120 - - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_01991 1.08e-86 dinB - - S - - - DinB family
EPKFIKFJ_01992 1.82e-231 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
EPKFIKFJ_01993 5.82e-16 - - - - - - - -
EPKFIKFJ_01994 2.04e-10 - - - - - - - -
EPKFIKFJ_01995 1.95e-39 - - - S - - - Protein of unknown function (DUF4025)
EPKFIKFJ_01996 1.69e-13 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EPKFIKFJ_01997 1.52e-164 yoaP - - K - - - YoaP-like
EPKFIKFJ_01998 1.09e-117 - - - J - - - Acetyltransferase (GNAT) domain
EPKFIKFJ_02000 1.87e-53 - - - - - - - -
EPKFIKFJ_02002 2.39e-130 - - - S - - - Domain of unknown function (DUF3885)
EPKFIKFJ_02003 1.34e-238 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKFIKFJ_02004 3.2e-150 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
EPKFIKFJ_02005 9.32e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
EPKFIKFJ_02006 1.97e-119 yvgO - - - - - - -
EPKFIKFJ_02008 0.0 yobO - - M - - - Pectate lyase superfamily protein
EPKFIKFJ_02009 1.33e-43 - - - S - - - TM2 domain
EPKFIKFJ_02010 9.69e-99 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
EPKFIKFJ_02011 3.99e-33 - - - S - - - Domain of unknown function (DUF4177)
EPKFIKFJ_02012 2.53e-162 yndL - - S - - - Replication protein
EPKFIKFJ_02013 4.12e-10 - - - - - - - -
EPKFIKFJ_02014 4.95e-182 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
EPKFIKFJ_02015 2.23e-86 yndM - - S - - - Protein of unknown function (DUF2512)
EPKFIKFJ_02017 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPKFIKFJ_02018 4.8e-66 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
EPKFIKFJ_02019 4.8e-141 yneB - - L - - - resolvase
EPKFIKFJ_02020 2.33e-43 ynzC - - S - - - UPF0291 protein
EPKFIKFJ_02021 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EPKFIKFJ_02022 3.48e-103 yneE - - S - - - Sporulation inhibitor of replication protein sirA
EPKFIKFJ_02023 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
EPKFIKFJ_02024 8.06e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
EPKFIKFJ_02025 1.38e-158 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
EPKFIKFJ_02026 4.11e-75 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
EPKFIKFJ_02027 7.59e-97 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
EPKFIKFJ_02028 4.28e-92 yneK - - S - - - Protein of unknown function (DUF2621)
EPKFIKFJ_02029 2.64e-77 cotM - - O ko:K06335 - ko00000 Spore coat protein
EPKFIKFJ_02030 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
EPKFIKFJ_02031 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
EPKFIKFJ_02032 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPKFIKFJ_02033 4.36e-114 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EPKFIKFJ_02035 4.08e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
EPKFIKFJ_02036 8.11e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
EPKFIKFJ_02037 5.95e-65 yneQ - - - - - - -
EPKFIKFJ_02038 9.38e-58 yneR - - S - - - Belongs to the HesB IscA family
EPKFIKFJ_02039 1.51e-119 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EPKFIKFJ_02040 1.41e-89 yneT - - S ko:K06929 - ko00000 CoA-binding protein
EPKFIKFJ_02041 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPKFIKFJ_02042 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPKFIKFJ_02043 2.21e-19 - - - - - - - -
EPKFIKFJ_02044 2.04e-60 ynfC - - - - - - -
EPKFIKFJ_02045 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
EPKFIKFJ_02046 1.56e-28 yndG - - S - - - DoxX-like family
EPKFIKFJ_02047 2.6e-98 - - - S - - - Domain of unknown function (DUF4166)
EPKFIKFJ_02048 0.0 yndJ - - S - - - YndJ-like protein
EPKFIKFJ_02049 2.03e-67 yvlA - - S - - - Domain of unknown function (DUF4870)
EPKFIKFJ_02050 3.49e-282 - - - T - - - Histidine kinase
EPKFIKFJ_02051 7.49e-155 - - - T - - - Transcriptional regulatory protein, C terminal
EPKFIKFJ_02052 4.05e-303 - 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
EPKFIKFJ_02053 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKFIKFJ_02054 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_02055 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_02056 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_02057 3.84e-262 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
EPKFIKFJ_02058 3.62e-156 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
EPKFIKFJ_02059 5.28e-135 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EPKFIKFJ_02060 2.32e-145 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EPKFIKFJ_02061 6.2e-207 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
EPKFIKFJ_02062 4.21e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EPKFIKFJ_02063 7.37e-158 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EPKFIKFJ_02064 3.12e-254 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
EPKFIKFJ_02065 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
EPKFIKFJ_02066 8.22e-171 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
EPKFIKFJ_02067 1.02e-88 yngA - - S - - - membrane
EPKFIKFJ_02068 1.01e-196 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EPKFIKFJ_02069 6.22e-134 yngC - - S - - - SNARE associated Golgi protein
EPKFIKFJ_02070 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EPKFIKFJ_02071 2.54e-171 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
EPKFIKFJ_02072 2.16e-208 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
EPKFIKFJ_02073 2.28e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
EPKFIKFJ_02074 1.6e-304 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
EPKFIKFJ_02075 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPKFIKFJ_02076 5.24e-43 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPKFIKFJ_02077 6.97e-264 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EPKFIKFJ_02078 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
EPKFIKFJ_02079 9.31e-83 yngL - - S - - - Protein of unknown function (DUF1360)
EPKFIKFJ_02080 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
EPKFIKFJ_02081 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_02082 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
EPKFIKFJ_02083 1.56e-229 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
EPKFIKFJ_02084 1.31e-305 yoeA - - V - - - MATE efflux family protein
EPKFIKFJ_02085 8.33e-122 yoeB - - S - - - IseA DL-endopeptidase inhibitor
EPKFIKFJ_02087 7.69e-123 - - - L - - - Integrase
EPKFIKFJ_02088 7.83e-46 yoeD - - G - - - Helix-turn-helix domain
EPKFIKFJ_02089 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EPKFIKFJ_02090 5.29e-237 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
EPKFIKFJ_02091 1.91e-66 - - - K - - - Helix-turn-helix domain
EPKFIKFJ_02092 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPKFIKFJ_02093 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
EPKFIKFJ_02094 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
EPKFIKFJ_02095 7.74e-201 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_02096 3.37e-251 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPKFIKFJ_02097 5.78e-173 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPKFIKFJ_02098 6.69e-81 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
EPKFIKFJ_02099 4.03e-156 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKFIKFJ_02100 1.23e-49 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EPKFIKFJ_02101 1.2e-147 yoxB - - - - - - -
EPKFIKFJ_02102 1.16e-120 - - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_02103 0.0 - - - I - - - PLD-like domain
EPKFIKFJ_02104 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_02105 6.56e-192 - - - S - - - membrane
EPKFIKFJ_02106 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
EPKFIKFJ_02107 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
EPKFIKFJ_02108 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EPKFIKFJ_02109 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EPKFIKFJ_02110 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKFIKFJ_02111 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
EPKFIKFJ_02113 4.04e-103 - - - - - - - -
EPKFIKFJ_02114 2.84e-123 tnpR - - L - - - resolvase
EPKFIKFJ_02115 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
EPKFIKFJ_02116 1.03e-248 yoaB - - EGP - - - the major facilitator superfamily
EPKFIKFJ_02117 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
EPKFIKFJ_02118 4.77e-203 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPKFIKFJ_02119 1.6e-13 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPKFIKFJ_02120 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPKFIKFJ_02121 6.3e-36 yoaF - - - - - - -
EPKFIKFJ_02123 6.83e-121 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_02124 1.52e-38 - - - - - - - -
EPKFIKFJ_02127 2.04e-68 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
EPKFIKFJ_02128 6.26e-156 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
EPKFIKFJ_02129 1.44e-110 yobS - - K - - - Transcriptional regulator
EPKFIKFJ_02130 1.22e-159 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKFIKFJ_02131 3.71e-117 yobW - - - - - - -
EPKFIKFJ_02132 3.14e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
EPKFIKFJ_02133 5.45e-154 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
EPKFIKFJ_02134 5.42e-117 yozB - - S ko:K08976 - ko00000 membrane
EPKFIKFJ_02135 9.94e-172 - - - J - - - Protein required for attachment to host cells
EPKFIKFJ_02136 2.99e-119 yocC - - - - - - -
EPKFIKFJ_02137 8.07e-233 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
EPKFIKFJ_02139 6.61e-157 yocH - - M - - - COG1388 FOG LysM repeat
EPKFIKFJ_02140 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKFIKFJ_02142 2.71e-143 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPKFIKFJ_02143 7.44e-78 yocK - - T - - - general stress protein
EPKFIKFJ_02145 1.16e-11 yocN - - - - - - -
EPKFIKFJ_02146 2.21e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EPKFIKFJ_02147 8.77e-41 yozN - - - - - - -
EPKFIKFJ_02148 1.83e-49 yocN - - - - - - -
EPKFIKFJ_02149 5.32e-75 yozO - - S - - - Bacterial PH domain
EPKFIKFJ_02151 4.69e-43 yozC - - - - - - -
EPKFIKFJ_02152 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPKFIKFJ_02153 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
EPKFIKFJ_02154 5.12e-207 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
EPKFIKFJ_02155 2.2e-293 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
EPKFIKFJ_02156 3.02e-209 yocS - - S ko:K03453 - ko00000 -transporter
EPKFIKFJ_02157 8.69e-156 - - - S - - - Metallo-beta-lactamase superfamily
EPKFIKFJ_02158 1.12e-257 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
EPKFIKFJ_02159 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
EPKFIKFJ_02160 0.0 yojO - - P - - - Von Willebrand factor
EPKFIKFJ_02161 2e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
EPKFIKFJ_02162 1.31e-135 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EPKFIKFJ_02163 1.68e-276 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
EPKFIKFJ_02164 6.89e-278 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
EPKFIKFJ_02165 3.97e-136 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPKFIKFJ_02167 1.51e-297 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
EPKFIKFJ_02168 6.24e-187 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKFIKFJ_02169 2.61e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
EPKFIKFJ_02170 4.69e-79 yojF - - S - - - Protein of unknown function (DUF1806)
EPKFIKFJ_02171 3.66e-31 - - - - - - - -
EPKFIKFJ_02172 3.04e-203 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
EPKFIKFJ_02173 1.83e-101 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
EPKFIKFJ_02175 9.37e-83 iolK - - S - - - tautomerase
EPKFIKFJ_02176 1.93e-69 yodB - - K - - - transcriptional
EPKFIKFJ_02177 6.14e-135 yodC - - C - - - nitroreductase
EPKFIKFJ_02178 1.12e-118 yahD - - S ko:K06999 - ko00000 Carboxylesterase
EPKFIKFJ_02179 8.81e-212 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
EPKFIKFJ_02180 1.14e-27 - - - S - - - Protein of unknown function (DUF3311)
EPKFIKFJ_02181 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPKFIKFJ_02182 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
EPKFIKFJ_02183 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKFIKFJ_02184 3.79e-164 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_02185 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EPKFIKFJ_02186 4.97e-156 yodH - - Q - - - Methyltransferase
EPKFIKFJ_02187 2.3e-30 yodI - - - - - - -
EPKFIKFJ_02188 8.69e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
EPKFIKFJ_02189 4.29e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
EPKFIKFJ_02191 1.16e-72 yodL - - S - - - YodL-like
EPKFIKFJ_02192 8.36e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
EPKFIKFJ_02193 1.97e-33 yozD - - S - - - YozD-like protein
EPKFIKFJ_02195 2.53e-154 yodN - - - - - - -
EPKFIKFJ_02196 1.39e-66 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKFIKFJ_02197 2.87e-47 yozE - - S - - - Belongs to the UPF0346 family
EPKFIKFJ_02198 6.45e-59 yokU - - S - - - YokU-like protein, putative antitoxin
EPKFIKFJ_02199 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
EPKFIKFJ_02200 4.82e-180 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
EPKFIKFJ_02201 4.03e-315 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
EPKFIKFJ_02202 8.26e-154 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
EPKFIKFJ_02203 5.2e-156 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EPKFIKFJ_02204 2.06e-297 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPKFIKFJ_02206 3.54e-83 - - - L - - - Bacterial transcription activator, effector binding domain
EPKFIKFJ_02208 3.96e-176 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EPKFIKFJ_02209 1.17e-286 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EPKFIKFJ_02210 2.84e-54 cgeC - - - ko:K06321 - ko00000 -
EPKFIKFJ_02211 1.08e-81 cgeA - - - ko:K06319 - ko00000 -
EPKFIKFJ_02212 6.45e-215 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EPKFIKFJ_02213 7.88e-267 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EPKFIKFJ_02214 5.78e-91 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EPKFIKFJ_02217 5.97e-151 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 FMN-dependent dehydrogenase
EPKFIKFJ_02219 6.05e-22 - - - S - - - Regulatory protein YrvL
EPKFIKFJ_02220 6.94e-262 yokA - - L - - - Recombinase
EPKFIKFJ_02221 1.29e-129 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EPKFIKFJ_02222 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EPKFIKFJ_02223 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPKFIKFJ_02224 1.42e-88 ypoP - - K - - - transcriptional
EPKFIKFJ_02225 2.45e-122 ypmS - - S - - - protein conserved in bacteria
EPKFIKFJ_02226 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EPKFIKFJ_02227 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EPKFIKFJ_02228 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
EPKFIKFJ_02229 7.88e-305 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPKFIKFJ_02230 1.54e-207 yplP - - K - - - Transcriptional regulator
EPKFIKFJ_02231 7.14e-141 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EPKFIKFJ_02232 9.83e-141 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EPKFIKFJ_02233 6.3e-110 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPKFIKFJ_02234 2.08e-202 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPKFIKFJ_02235 1.41e-142 ypjP - - S - - - YpjP-like protein
EPKFIKFJ_02236 2.63e-167 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
EPKFIKFJ_02237 1.38e-98 yphP - - S - - - Belongs to the UPF0403 family
EPKFIKFJ_02238 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
EPKFIKFJ_02239 8.12e-197 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
EPKFIKFJ_02240 1.69e-116 yagB - - S ko:K06950 - ko00000 phosphohydrolase
EPKFIKFJ_02241 4.95e-107 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
EPKFIKFJ_02243 1.56e-225 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EPKFIKFJ_02244 1.01e-272 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
EPKFIKFJ_02245 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
EPKFIKFJ_02246 4.27e-16 degR - - - - - - -
EPKFIKFJ_02247 5.37e-48 - - - S - - - Protein of unknown function (DUF2564)
EPKFIKFJ_02248 6.37e-38 ypeQ - - S - - - Zinc-finger
EPKFIKFJ_02249 4.29e-152 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
EPKFIKFJ_02250 3.96e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EPKFIKFJ_02251 3.51e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
EPKFIKFJ_02253 2.07e-204 ypcP - - L - - - 5'3' exonuclease
EPKFIKFJ_02254 5.97e-11 - - - - - - - -
EPKFIKFJ_02255 3e-45 ypbS - - S - - - Protein of unknown function (DUF2533)
EPKFIKFJ_02256 0.0 ypbR - - S - - - Dynamin family
EPKFIKFJ_02257 7.39e-111 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
EPKFIKFJ_02258 3.81e-254 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
EPKFIKFJ_02259 2.22e-130 - - - J - - - Acetyltransferase (GNAT) domain
EPKFIKFJ_02260 8.02e-60 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
EPKFIKFJ_02261 2.2e-09 - - - S - - - Bacillus cereus group antimicrobial protein
EPKFIKFJ_02262 4.64e-294 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
EPKFIKFJ_02263 8.76e-124 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPKFIKFJ_02264 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EPKFIKFJ_02265 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
EPKFIKFJ_02267 6.91e-31 - - - S - - - YpzG-like protein
EPKFIKFJ_02268 2.19e-96 yqgA - - - - - - -
EPKFIKFJ_02269 3.07e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
EPKFIKFJ_02270 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EPKFIKFJ_02271 3.67e-126 ypsA - - S - - - Belongs to the UPF0398 family
EPKFIKFJ_02272 5.48e-36 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
EPKFIKFJ_02274 3.33e-285 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
EPKFIKFJ_02275 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
EPKFIKFJ_02276 6.99e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
EPKFIKFJ_02277 5.45e-79 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
EPKFIKFJ_02278 2.64e-59 yppG - - S - - - YppG-like protein
EPKFIKFJ_02283 1.05e-225 yppC - - S - - - Protein of unknown function (DUF2515)
EPKFIKFJ_02284 8.49e-144 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPKFIKFJ_02285 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EPKFIKFJ_02286 4.6e-113 ypoC - - - - - - -
EPKFIKFJ_02287 1.63e-154 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPKFIKFJ_02288 8.05e-166 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
EPKFIKFJ_02289 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
EPKFIKFJ_02290 1.1e-278 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
EPKFIKFJ_02291 2.74e-95 ypmB - - S - - - protein conserved in bacteria
EPKFIKFJ_02292 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
EPKFIKFJ_02293 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
EPKFIKFJ_02294 1.98e-83 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EPKFIKFJ_02295 4.82e-194 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EPKFIKFJ_02296 1.89e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
EPKFIKFJ_02297 2.04e-226 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EPKFIKFJ_02298 1.53e-266 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EPKFIKFJ_02299 7.01e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
EPKFIKFJ_02300 3.8e-162 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
EPKFIKFJ_02301 3.58e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
EPKFIKFJ_02302 9.38e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPKFIKFJ_02303 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
EPKFIKFJ_02304 6.13e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKFIKFJ_02305 5.93e-282 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EPKFIKFJ_02306 1.09e-177 ypjB - - S - - - sporulation protein
EPKFIKFJ_02307 6.12e-126 ypjA - - S - - - membrane
EPKFIKFJ_02308 9.48e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
EPKFIKFJ_02309 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
EPKFIKFJ_02310 2.27e-124 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
EPKFIKFJ_02311 1.21e-94 ypiF - - S - - - Protein of unknown function (DUF2487)
EPKFIKFJ_02312 2.14e-128 ypiB - - S - - - Belongs to the UPF0302 family
EPKFIKFJ_02313 7.68e-292 ypiA - - S - - - COG0457 FOG TPR repeat
EPKFIKFJ_02314 3.11e-289 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EPKFIKFJ_02315 9.38e-256 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
EPKFIKFJ_02316 2.67e-251 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPKFIKFJ_02317 1.08e-175 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EPKFIKFJ_02318 9.2e-286 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EPKFIKFJ_02319 2.57e-141 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
EPKFIKFJ_02320 1.15e-158 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
EPKFIKFJ_02321 3.8e-201 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPKFIKFJ_02322 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPKFIKFJ_02323 8.09e-77 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
EPKFIKFJ_02324 1.14e-253 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EPKFIKFJ_02325 3.26e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPKFIKFJ_02326 8e-178 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
EPKFIKFJ_02327 2.01e-102 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EPKFIKFJ_02328 5.39e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EPKFIKFJ_02329 2.6e-167 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EPKFIKFJ_02330 2.68e-175 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
EPKFIKFJ_02331 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
EPKFIKFJ_02332 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
EPKFIKFJ_02333 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPKFIKFJ_02334 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
EPKFIKFJ_02336 4.09e-165 yphF - - - - - - -
EPKFIKFJ_02337 1.13e-23 yphE - - S - - - Protein of unknown function (DUF2768)
EPKFIKFJ_02338 9.14e-240 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
EPKFIKFJ_02339 2.86e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
EPKFIKFJ_02340 6.38e-129 yphA - - - - - - -
EPKFIKFJ_02341 1.32e-12 - - - S - - - YpzI-like protein
EPKFIKFJ_02342 4.76e-228 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EPKFIKFJ_02343 3.17e-261 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
EPKFIKFJ_02344 3.75e-142 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
EPKFIKFJ_02345 1.12e-17 - - - S - - - Family of unknown function (DUF5359)
EPKFIKFJ_02346 6.58e-72 ypfA - - M - - - Flagellar protein YcgR
EPKFIKFJ_02347 1.1e-311 ypeB - - H ko:K06313 - ko00000 sporulation protein
EPKFIKFJ_02348 2.15e-203 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
EPKFIKFJ_02349 2.61e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
EPKFIKFJ_02350 5.93e-236 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
EPKFIKFJ_02351 8.6e-310 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EPKFIKFJ_02352 7.9e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
EPKFIKFJ_02353 5.62e-181 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
EPKFIKFJ_02354 1.52e-108 ypbF - - S - - - Protein of unknown function (DUF2663)
EPKFIKFJ_02355 8.85e-110 ypbE - - M - - - Lysin motif
EPKFIKFJ_02356 1.84e-123 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
EPKFIKFJ_02357 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKFIKFJ_02358 2.97e-244 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
EPKFIKFJ_02359 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
EPKFIKFJ_02360 3.59e-121 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPKFIKFJ_02361 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPKFIKFJ_02362 6.63e-216 rsiX - - - - - - -
EPKFIKFJ_02363 3.09e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
EPKFIKFJ_02364 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_02365 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_02366 3.09e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
EPKFIKFJ_02367 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
EPKFIKFJ_02368 9.77e-125 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
EPKFIKFJ_02369 1.74e-166 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EPKFIKFJ_02370 7.39e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
EPKFIKFJ_02371 6.22e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
EPKFIKFJ_02372 2.36e-268 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPKFIKFJ_02373 5.9e-107 ypuI - - S - - - Protein of unknown function (DUF3907)
EPKFIKFJ_02374 1.3e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPKFIKFJ_02375 4.93e-165 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPKFIKFJ_02377 2.41e-113 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
EPKFIKFJ_02378 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKFIKFJ_02379 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EPKFIKFJ_02380 8.2e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EPKFIKFJ_02381 1.09e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
EPKFIKFJ_02382 1.24e-257 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPKFIKFJ_02383 7.86e-68 ypuD - - - - - - -
EPKFIKFJ_02384 8.88e-122 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
EPKFIKFJ_02385 6.23e-102 ccdC1 - - O - - - Protein of unknown function (DUF1453)
EPKFIKFJ_02386 1.18e-103 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPKFIKFJ_02387 3.35e-194 ypuA - - S - - - Secreted protein
EPKFIKFJ_02388 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPKFIKFJ_02389 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
EPKFIKFJ_02390 1.2e-138 - - - S ko:K06407 - ko00000 stage V sporulation protein
EPKFIKFJ_02391 3.57e-74 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
EPKFIKFJ_02392 9.17e-241 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EPKFIKFJ_02393 2.85e-103 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EPKFIKFJ_02394 7.71e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
EPKFIKFJ_02395 9.1e-141 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
EPKFIKFJ_02396 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKFIKFJ_02397 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
EPKFIKFJ_02398 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
EPKFIKFJ_02399 5.58e-270 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
EPKFIKFJ_02400 8.69e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EPKFIKFJ_02401 4.39e-288 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPKFIKFJ_02402 1.78e-210 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
EPKFIKFJ_02403 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
EPKFIKFJ_02404 3.08e-102 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
EPKFIKFJ_02405 4.12e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
EPKFIKFJ_02406 2.87e-43 yqkK - - - - - - -
EPKFIKFJ_02407 5.05e-33 - - - - - - - -
EPKFIKFJ_02408 9.28e-307 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EPKFIKFJ_02409 3.56e-313 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EPKFIKFJ_02410 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
EPKFIKFJ_02411 4.88e-236 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
EPKFIKFJ_02412 2.32e-75 ansR - - K - - - Transcriptional regulator
EPKFIKFJ_02413 1.43e-271 yqxK - - L - - - DNA helicase
EPKFIKFJ_02414 1.42e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
EPKFIKFJ_02415 5.78e-10 - - - S - - - Protein of unknown function (DUF3936)
EPKFIKFJ_02416 2.34e-211 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EPKFIKFJ_02417 3.06e-15 yqkE - - S - - - Protein of unknown function (DUF3886)
EPKFIKFJ_02418 3.86e-169 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
EPKFIKFJ_02419 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
EPKFIKFJ_02420 1.22e-76 yqkB - - S - - - Belongs to the HesB IscA family
EPKFIKFJ_02421 1.93e-212 yqkA - - K - - - GrpB protein
EPKFIKFJ_02422 1.92e-08 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
EPKFIKFJ_02423 2.7e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
EPKFIKFJ_02424 6.1e-295 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPKFIKFJ_02425 7.27e-73 - - - S - - - YolD-like protein
EPKFIKFJ_02427 7.76e-204 yueF - - S - - - transporter activity
EPKFIKFJ_02429 3.01e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
EPKFIKFJ_02430 4.1e-307 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
EPKFIKFJ_02431 2.99e-174 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKFIKFJ_02432 1.11e-213 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKFIKFJ_02433 7.56e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPKFIKFJ_02434 9.08e-202 - - - K - - - LysR substrate binding domain
EPKFIKFJ_02435 2.42e-61 - - - S - - - GlpM protein
EPKFIKFJ_02436 1.64e-120 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EPKFIKFJ_02437 4.49e-63 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
EPKFIKFJ_02438 2.4e-184 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EPKFIKFJ_02439 4.44e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EPKFIKFJ_02440 2.97e-215 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EPKFIKFJ_02441 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPKFIKFJ_02442 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPKFIKFJ_02443 7.78e-294 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPKFIKFJ_02444 1.36e-36 yqzJ - - - - - - -
EPKFIKFJ_02445 6.56e-188 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPKFIKFJ_02446 4.14e-256 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
EPKFIKFJ_02447 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
EPKFIKFJ_02448 6.09e-92 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
EPKFIKFJ_02450 3.99e-118 yqjB - - S - - - protein conserved in bacteria
EPKFIKFJ_02451 1.79e-216 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
EPKFIKFJ_02452 2.77e-161 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKFIKFJ_02453 6.03e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
EPKFIKFJ_02454 2.18e-170 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EPKFIKFJ_02455 1.68e-99 yqiW - - S - - - Belongs to the UPF0403 family
EPKFIKFJ_02456 3.22e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EPKFIKFJ_02457 2.69e-265 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPKFIKFJ_02458 4e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EPKFIKFJ_02459 4.18e-217 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
EPKFIKFJ_02460 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
EPKFIKFJ_02461 3.86e-260 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
EPKFIKFJ_02462 5.27e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EPKFIKFJ_02463 1.53e-191 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
EPKFIKFJ_02464 0.0 bkdR - - KT - - - Transcriptional regulator
EPKFIKFJ_02465 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
EPKFIKFJ_02466 7.1e-199 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EPKFIKFJ_02467 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
EPKFIKFJ_02468 9.85e-261 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EPKFIKFJ_02469 9.37e-256 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
EPKFIKFJ_02470 8.59e-59 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EPKFIKFJ_02471 1.22e-101 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
EPKFIKFJ_02472 1.21e-266 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
EPKFIKFJ_02473 1.04e-163 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
EPKFIKFJ_02474 1.94e-127 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
EPKFIKFJ_02476 2.52e-119 - - - P - - - Probably functions as a manganese efflux pump
EPKFIKFJ_02477 3.85e-144 - - - K - - - Protein of unknown function (DUF1232)
EPKFIKFJ_02479 2.85e-266 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
EPKFIKFJ_02482 4.31e-260 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPKFIKFJ_02484 4.13e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
EPKFIKFJ_02485 5.48e-298 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
EPKFIKFJ_02486 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
EPKFIKFJ_02487 1.03e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
EPKFIKFJ_02488 2.69e-193 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
EPKFIKFJ_02489 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPKFIKFJ_02490 7.16e-201 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
EPKFIKFJ_02491 4.44e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPKFIKFJ_02492 5.36e-308 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPKFIKFJ_02493 2.51e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPKFIKFJ_02494 2.58e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPKFIKFJ_02495 5.53e-87 yqhY - - S - - - protein conserved in bacteria
EPKFIKFJ_02496 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EPKFIKFJ_02497 2.59e-83 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EPKFIKFJ_02498 1.88e-86 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
EPKFIKFJ_02499 1.3e-145 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
EPKFIKFJ_02500 1.74e-129 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
EPKFIKFJ_02501 3.02e-260 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
EPKFIKFJ_02502 5.28e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
EPKFIKFJ_02503 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
EPKFIKFJ_02504 2.23e-108 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
EPKFIKFJ_02505 7.55e-213 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
EPKFIKFJ_02506 1.64e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
EPKFIKFJ_02507 9.69e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPKFIKFJ_02508 2.75e-245 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
EPKFIKFJ_02509 2.13e-113 yqhR - - S - - - Conserved membrane protein YqhR
EPKFIKFJ_02510 1.12e-215 yqhQ - - S - - - Protein of unknown function (DUF1385)
EPKFIKFJ_02511 8.59e-80 yqhP - - - - - - -
EPKFIKFJ_02512 2.51e-203 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
EPKFIKFJ_02513 1.14e-96 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
EPKFIKFJ_02514 1.25e-201 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
EPKFIKFJ_02515 2.33e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
EPKFIKFJ_02516 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EPKFIKFJ_02517 2.14e-313 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EPKFIKFJ_02518 7.69e-254 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
EPKFIKFJ_02519 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EPKFIKFJ_02520 8.42e-193 yqhG - - S - - - Bacterial protein YqhG of unknown function
EPKFIKFJ_02521 1.3e-29 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
EPKFIKFJ_02522 2.27e-71 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
EPKFIKFJ_02523 8.28e-178 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
EPKFIKFJ_02524 5.48e-95 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
EPKFIKFJ_02525 7.32e-144 yqxM - - - ko:K19433 - ko00000 -
EPKFIKFJ_02526 3.98e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
EPKFIKFJ_02527 9.56e-35 yqzE - - S - - - YqzE-like protein
EPKFIKFJ_02528 8.44e-75 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
EPKFIKFJ_02529 2.45e-28 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
EPKFIKFJ_02530 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
EPKFIKFJ_02531 3.1e-91 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
EPKFIKFJ_02532 1.5e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
EPKFIKFJ_02533 5.79e-227 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
EPKFIKFJ_02534 5.85e-253 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EPKFIKFJ_02535 1.34e-231 yqxL - - P - - - Mg2 transporter protein
EPKFIKFJ_02536 2.13e-294 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKFIKFJ_02537 2.41e-175 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
EPKFIKFJ_02539 2.15e-82 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
EPKFIKFJ_02540 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
EPKFIKFJ_02541 2e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
EPKFIKFJ_02542 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
EPKFIKFJ_02543 2.02e-63 dglA - - S - - - Thiamine-binding protein
EPKFIKFJ_02544 1.57e-239 yqgU - - - - - - -
EPKFIKFJ_02545 1.33e-256 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
EPKFIKFJ_02546 1.18e-227 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
EPKFIKFJ_02547 1.87e-37 yqgQ - - S - - - Protein conserved in bacteria
EPKFIKFJ_02548 2.58e-269 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
EPKFIKFJ_02549 5.38e-11 yqgO - - - - - - -
EPKFIKFJ_02550 7.01e-116 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPKFIKFJ_02551 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
EPKFIKFJ_02552 3.42e-68 yqzD - - - - - - -
EPKFIKFJ_02553 1.97e-96 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPKFIKFJ_02554 2.71e-187 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPKFIKFJ_02555 2.99e-179 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPKFIKFJ_02556 1.88e-195 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
EPKFIKFJ_02557 1.75e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
EPKFIKFJ_02558 6.14e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
EPKFIKFJ_02559 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
EPKFIKFJ_02560 5.94e-283 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
EPKFIKFJ_02561 8.52e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
EPKFIKFJ_02562 7.59e-97 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
EPKFIKFJ_02563 8.5e-165 yqgB - - S - - - Protein of unknown function (DUF1189)
EPKFIKFJ_02564 5.95e-59 yqfZ - - M ko:K06417 - ko00000 LysM domain
EPKFIKFJ_02565 1.09e-253 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EPKFIKFJ_02566 3.9e-79 yqfX - - S - - - membrane
EPKFIKFJ_02567 3.23e-139 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
EPKFIKFJ_02568 2.63e-99 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
EPKFIKFJ_02569 2.47e-195 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKFIKFJ_02570 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
EPKFIKFJ_02571 9.16e-209 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EPKFIKFJ_02572 3.91e-304 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EPKFIKFJ_02573 7.12e-57 yqfQ - - S - - - YqfQ-like protein
EPKFIKFJ_02574 4.12e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EPKFIKFJ_02575 2.97e-266 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPKFIKFJ_02576 1.65e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
EPKFIKFJ_02577 7.67e-80 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EPKFIKFJ_02578 8e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPKFIKFJ_02579 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPKFIKFJ_02580 4.54e-111 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
EPKFIKFJ_02581 1.75e-188 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
EPKFIKFJ_02582 3.41e-144 ccpN - - K - - - CBS domain
EPKFIKFJ_02583 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
EPKFIKFJ_02584 2.03e-220 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
EPKFIKFJ_02585 1.9e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
EPKFIKFJ_02586 6e-24 - - - S - - - YqzL-like protein
EPKFIKFJ_02587 2.86e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPKFIKFJ_02588 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EPKFIKFJ_02589 8.76e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
EPKFIKFJ_02590 2.91e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPKFIKFJ_02591 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
EPKFIKFJ_02592 4.78e-222 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
EPKFIKFJ_02593 3.96e-273 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
EPKFIKFJ_02594 3.57e-61 yqfC - - S - - - sporulation protein YqfC
EPKFIKFJ_02595 2.58e-48 yqfB - - - - - - -
EPKFIKFJ_02596 1.22e-186 yqfA - - S - - - UPF0365 protein
EPKFIKFJ_02597 3.91e-288 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
EPKFIKFJ_02598 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
EPKFIKFJ_02599 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
EPKFIKFJ_02600 1.99e-194 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
EPKFIKFJ_02601 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
EPKFIKFJ_02602 3.96e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPKFIKFJ_02603 1.27e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
EPKFIKFJ_02604 6.71e-264 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPKFIKFJ_02605 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
EPKFIKFJ_02606 1.99e-104 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPKFIKFJ_02607 2.33e-239 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPKFIKFJ_02608 3.95e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
EPKFIKFJ_02609 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPKFIKFJ_02610 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
EPKFIKFJ_02611 2.6e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
EPKFIKFJ_02612 1.02e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
EPKFIKFJ_02613 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
EPKFIKFJ_02614 6.09e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
EPKFIKFJ_02615 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
EPKFIKFJ_02616 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
EPKFIKFJ_02617 1.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
EPKFIKFJ_02618 1.14e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPKFIKFJ_02619 1.98e-177 yqeM - - Q - - - Methyltransferase
EPKFIKFJ_02620 9.39e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPKFIKFJ_02621 3.25e-131 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
EPKFIKFJ_02622 1.38e-138 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPKFIKFJ_02623 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
EPKFIKFJ_02624 2.83e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EPKFIKFJ_02625 1.87e-270 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EPKFIKFJ_02626 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
EPKFIKFJ_02628 3.99e-176 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
EPKFIKFJ_02629 3.16e-178 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
EPKFIKFJ_02630 3.41e-137 yqeD - - S - - - SNARE associated Golgi protein
EPKFIKFJ_02632 9.72e-08 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EPKFIKFJ_02633 2.47e-274 - - - EGP - - - Transmembrane secretion effector
EPKFIKFJ_02634 6.78e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EPKFIKFJ_02635 1.82e-17 - - - L ko:K06400 - ko00000 Recombinase
EPKFIKFJ_02636 1.46e-194 - - - L - - - AAA ATPase domain
EPKFIKFJ_02637 1.18e-50 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPKFIKFJ_02640 7.65e-201 smvA - - EGP ko:K08167 - ko00000,ko00002,ko01504,ko02000 Major facilitator superfamily
EPKFIKFJ_02641 2.93e-98 trpG 2.6.1.85, 4.1.3.27 - EH ko:K01658,ko:K01664 ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 TIGRFAM glutamine amidotransferase of anthranilate synthase
EPKFIKFJ_02642 1.71e-224 - 4.1.3.27, 4.2.99.21, 5.4.4.2 - EH ko:K01657,ko:K04781 ko00400,ko00405,ko01053,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01053,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Anthranilate synthase component I domain protein
EPKFIKFJ_02643 4.17e-221 - 6.2.1.30 - H ko:K01912 ko00360,ko01120,ko05111,map00360,map01120,map05111 ko00000,ko00001,ko01000 phenylacetate-CoA ligase activity
EPKFIKFJ_02644 0.0 - - - Q - - - AMP-binding enzyme C-terminal domain
EPKFIKFJ_02645 4.19e-152 - - - S - - - Winged helix DNA-binding domain
EPKFIKFJ_02646 5.94e-257 glyA_1 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPKFIKFJ_02647 2.82e-142 mchB - - Q ko:K12240 ko01053,map01053 ko00000,ko00001,ko01008 Thioesterase involved in non-ribosomal peptide biosynthesis
EPKFIKFJ_02649 1.28e-206 - - - K ko:K13572 - ko00000,ko03051 HTH domain
EPKFIKFJ_02650 2.68e-135 lin0465 - - S - - - DJ-1/PfpI family
EPKFIKFJ_02651 1.39e-24 - - - - - - - -
EPKFIKFJ_02655 2.77e-18 - - - S - - - SMI1-KNR4 cell-wall
EPKFIKFJ_02656 5.49e-13 - - - S - - - SMI1-KNR4 cell-wall
EPKFIKFJ_02658 8.55e-19 xkdS - - S - - - Protein of unknown function (DUF2634)
EPKFIKFJ_02659 8.03e-141 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
EPKFIKFJ_02660 8.72e-34 xkdR - - S - - - Protein of unknown function (DUF2577)
EPKFIKFJ_02661 1.23e-174 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
EPKFIKFJ_02662 1.29e-89 - - - K - - - MerR family transcriptional regulator
EPKFIKFJ_02663 6.77e-21 xkdG - - S - - - Phage capsid family
EPKFIKFJ_02664 7.23e-202 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
EPKFIKFJ_02665 1.02e-79 - - - K - - - Transcriptional regulator PadR-like family
EPKFIKFJ_02666 3.5e-47 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
EPKFIKFJ_02668 1.84e-126 yqaC - - F - - - adenylate kinase activity
EPKFIKFJ_02669 5.34e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_02670 6.08e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
EPKFIKFJ_02671 2.76e-120 - - - S - - - DinB family
EPKFIKFJ_02673 1.14e-187 supH - - S - - - hydrolase
EPKFIKFJ_02674 5.2e-93 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
EPKFIKFJ_02675 7.33e-67 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
EPKFIKFJ_02676 2.38e-167 - - - K - - - Helix-turn-helix domain, rpiR family
EPKFIKFJ_02677 9.08e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EPKFIKFJ_02678 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_02679 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
EPKFIKFJ_02680 9.54e-229 romA - - S - - - Beta-lactamase superfamily domain
EPKFIKFJ_02681 1.88e-106 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPKFIKFJ_02682 5.33e-211 yybE - - K - - - Transcriptional regulator
EPKFIKFJ_02683 1.32e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_02684 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
EPKFIKFJ_02685 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
EPKFIKFJ_02686 3.67e-120 yrhH - - Q - - - methyltransferase
EPKFIKFJ_02687 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
EPKFIKFJ_02688 4.62e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
EPKFIKFJ_02689 1.48e-78 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
EPKFIKFJ_02690 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
EPKFIKFJ_02691 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
EPKFIKFJ_02692 1.35e-46 yrhC - - S - - - YrhC-like protein
EPKFIKFJ_02693 7.59e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
EPKFIKFJ_02694 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
EPKFIKFJ_02695 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPKFIKFJ_02696 1.4e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
EPKFIKFJ_02697 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
EPKFIKFJ_02698 8.77e-104 yrrS - - S - - - Protein of unknown function (DUF1510)
EPKFIKFJ_02699 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
EPKFIKFJ_02700 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPKFIKFJ_02702 2.49e-09 - - - - - - - -
EPKFIKFJ_02704 7.6e-143 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_02705 2.74e-77 - - - S - - - Pfam:Phage_holin_4_1
EPKFIKFJ_02708 7.52e-212 - - - S - - - Domain of unknown function (DUF2479)
EPKFIKFJ_02709 0.0 - - - M - - - Pectate lyase superfamily protein
EPKFIKFJ_02710 0.0 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
EPKFIKFJ_02711 1.62e-149 - - - S - - - Phage tail protein
EPKFIKFJ_02712 0.0 - - - D - - - Phage tail tape measure protein
EPKFIKFJ_02714 3.24e-42 - - - S - - - Phage tail tube protein
EPKFIKFJ_02716 4.65e-46 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
EPKFIKFJ_02717 1.05e-40 - - - S - - - Phage head-tail joining protein
EPKFIKFJ_02718 5.7e-11 - - - S - - - Phage gp6-like head-tail connector protein
EPKFIKFJ_02719 6.27e-29 - - - - - - - -
EPKFIKFJ_02720 4.85e-160 - - - S - - - capsid protein
EPKFIKFJ_02721 8.38e-96 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
EPKFIKFJ_02722 5.15e-221 - - - S - - - portal protein
EPKFIKFJ_02724 6.45e-182 terL - - S - - - Terminase
EPKFIKFJ_02725 2.38e-74 - - - L - - - Terminase, small subunit
EPKFIKFJ_02727 1.98e-11 ftsK - - D ko:K03466 - ko00000,ko03036 PFAM cell divisionFtsK SpoIIIE
EPKFIKFJ_02728 2.64e-93 - - - L - - - Phage integrase family
EPKFIKFJ_02729 4.1e-70 - - - M - - - ArpU family transcriptional regulator
EPKFIKFJ_02734 4.86e-59 - - - S - - - dUTPase
EPKFIKFJ_02736 5.46e-216 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EPKFIKFJ_02739 4.55e-21 yqaO - - S - - - Phage-like element PBSX protein XtrA
EPKFIKFJ_02740 3.79e-06 - - - - - - - -
EPKFIKFJ_02743 2.97e-36 - - - - - - - -
EPKFIKFJ_02746 9.57e-22 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
EPKFIKFJ_02747 2.54e-88 - - - L - - - dnaD_dom DnaD domain protein
EPKFIKFJ_02749 3.65e-09 - - - K - - - Psort location CytoplasmicMembrane, score
EPKFIKFJ_02750 3.64e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_02753 5.82e-160 - - - - - - - -
EPKFIKFJ_02754 2.32e-81 - - - L - - - Arm DNA-binding domain
EPKFIKFJ_02755 6.9e-145 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
EPKFIKFJ_02756 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
EPKFIKFJ_02757 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
EPKFIKFJ_02758 4.49e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
EPKFIKFJ_02759 7.74e-257 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPKFIKFJ_02760 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
EPKFIKFJ_02761 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPKFIKFJ_02762 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
EPKFIKFJ_02763 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPKFIKFJ_02764 4.09e-231 yrrI - - S - - - AI-2E family transporter
EPKFIKFJ_02765 1.43e-164 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKFIKFJ_02766 5.82e-185 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
EPKFIKFJ_02767 4.6e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKFIKFJ_02768 1.41e-134 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKFIKFJ_02769 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
EPKFIKFJ_02770 8.4e-42 yrzR - - - - - - -
EPKFIKFJ_02771 9e-101 yrrD - - S - - - protein conserved in bacteria
EPKFIKFJ_02772 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EPKFIKFJ_02773 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
EPKFIKFJ_02774 8.02e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EPKFIKFJ_02775 2.35e-266 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EPKFIKFJ_02776 3.74e-83 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_02777 4.18e-300 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
EPKFIKFJ_02778 1.68e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
EPKFIKFJ_02779 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EPKFIKFJ_02780 7.9e-306 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
EPKFIKFJ_02783 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
EPKFIKFJ_02784 4.07e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPKFIKFJ_02785 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPKFIKFJ_02786 1.71e-116 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPKFIKFJ_02787 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
EPKFIKFJ_02788 7.18e-59 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
EPKFIKFJ_02789 3.74e-104 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
EPKFIKFJ_02790 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EPKFIKFJ_02791 2.26e-64 yrzD - - S - - - Post-transcriptional regulator
EPKFIKFJ_02792 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKFIKFJ_02793 1.16e-133 yrbG - - S - - - membrane
EPKFIKFJ_02794 3.7e-80 yrzE - - S - - - Protein of unknown function (DUF3792)
EPKFIKFJ_02795 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
EPKFIKFJ_02796 9.18e-290 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EPKFIKFJ_02797 7.88e-244 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EPKFIKFJ_02798 3.4e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
EPKFIKFJ_02799 6.61e-232 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPKFIKFJ_02800 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPKFIKFJ_02801 1.16e-118 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
EPKFIKFJ_02803 8.39e-34 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKFIKFJ_02804 1.61e-214 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
EPKFIKFJ_02805 4.89e-262 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EPKFIKFJ_02806 1.3e-180 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
EPKFIKFJ_02807 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
EPKFIKFJ_02808 8.23e-269 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EPKFIKFJ_02809 1.49e-115 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
EPKFIKFJ_02810 4.34e-201 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
EPKFIKFJ_02811 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
EPKFIKFJ_02812 2.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPKFIKFJ_02813 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
EPKFIKFJ_02814 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
EPKFIKFJ_02815 5.78e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
EPKFIKFJ_02816 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
EPKFIKFJ_02817 3.7e-199 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
EPKFIKFJ_02818 2.65e-177 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EPKFIKFJ_02819 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
EPKFIKFJ_02820 1.61e-153 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
EPKFIKFJ_02821 3.98e-107 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
EPKFIKFJ_02822 2.51e-201 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
EPKFIKFJ_02823 2.91e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
EPKFIKFJ_02824 1.19e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
EPKFIKFJ_02825 1.6e-128 maf - - D ko:K06287 - ko00000 septum formation protein Maf
EPKFIKFJ_02826 2.51e-192 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
EPKFIKFJ_02827 1.4e-159 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
EPKFIKFJ_02828 2.79e-293 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
EPKFIKFJ_02829 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPKFIKFJ_02830 3.61e-34 - - - - - - - -
EPKFIKFJ_02831 3.17e-234 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EPKFIKFJ_02832 5.07e-232 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
EPKFIKFJ_02833 4.08e-306 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
EPKFIKFJ_02834 1.98e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
EPKFIKFJ_02835 4.99e-176 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
EPKFIKFJ_02836 6.05e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
EPKFIKFJ_02837 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
EPKFIKFJ_02838 2.79e-311 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EPKFIKFJ_02839 3.63e-110 ysxD - - - - - - -
EPKFIKFJ_02840 8.88e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
EPKFIKFJ_02841 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EPKFIKFJ_02842 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
EPKFIKFJ_02843 8.92e-291 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPKFIKFJ_02844 1.21e-284 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPKFIKFJ_02845 6.44e-239 ysoA - - H - - - Tetratricopeptide repeat
EPKFIKFJ_02846 1.04e-147 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPKFIKFJ_02847 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPKFIKFJ_02848 2.66e-249 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EPKFIKFJ_02849 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EPKFIKFJ_02850 6.75e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPKFIKFJ_02851 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EPKFIKFJ_02852 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
EPKFIKFJ_02857 1.78e-113 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
EPKFIKFJ_02858 3.07e-129 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPKFIKFJ_02859 2.38e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EPKFIKFJ_02860 1.05e-253 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
EPKFIKFJ_02861 1.06e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
EPKFIKFJ_02862 7.32e-95 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
EPKFIKFJ_02863 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_02864 8.26e-96 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
EPKFIKFJ_02865 1.77e-188 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EPKFIKFJ_02866 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
EPKFIKFJ_02867 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
EPKFIKFJ_02868 9.97e-103 yslB - - S - - - Protein of unknown function (DUF2507)
EPKFIKFJ_02869 9.22e-270 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
EPKFIKFJ_02870 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPKFIKFJ_02871 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
EPKFIKFJ_02872 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
EPKFIKFJ_02873 5.59e-224 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
EPKFIKFJ_02874 5.83e-176 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
EPKFIKFJ_02875 2.18e-172 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
EPKFIKFJ_02876 1.78e-133 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_02877 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
EPKFIKFJ_02878 9.33e-150 ywbB - - S - - - Protein of unknown function (DUF2711)
EPKFIKFJ_02879 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
EPKFIKFJ_02880 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EPKFIKFJ_02881 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
EPKFIKFJ_02882 2.02e-107 yshB - - S - - - membrane protein, required for colicin V production
EPKFIKFJ_02883 4.23e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EPKFIKFJ_02884 1.64e-210 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPKFIKFJ_02885 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPKFIKFJ_02886 1.27e-248 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPKFIKFJ_02887 1.94e-165 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPKFIKFJ_02888 8.83e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
EPKFIKFJ_02889 5.97e-244 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
EPKFIKFJ_02890 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
EPKFIKFJ_02891 5e-309 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
EPKFIKFJ_02892 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
EPKFIKFJ_02893 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
EPKFIKFJ_02894 1.27e-186 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
EPKFIKFJ_02895 8.11e-211 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
EPKFIKFJ_02896 2.69e-312 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
EPKFIKFJ_02897 2.36e-269 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
EPKFIKFJ_02898 1.33e-175 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
EPKFIKFJ_02899 2.82e-169 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
EPKFIKFJ_02900 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
EPKFIKFJ_02901 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
EPKFIKFJ_02902 4.34e-235 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKFIKFJ_02903 1.52e-262 ysdC - - G - - - COG1363 Cellulase M and related proteins
EPKFIKFJ_02904 4.11e-82 ysdB - - S - - - Sigma-w pathway protein YsdB
EPKFIKFJ_02905 5.91e-51 ysdA - - S - - - Membrane
EPKFIKFJ_02906 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPKFIKFJ_02907 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
EPKFIKFJ_02908 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPKFIKFJ_02909 1.21e-144 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
EPKFIKFJ_02910 3.04e-64 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
EPKFIKFJ_02911 8.26e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
EPKFIKFJ_02912 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_02913 2.22e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
EPKFIKFJ_02914 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPKFIKFJ_02915 6.12e-192 ytxC - - S - - - YtxC-like family
EPKFIKFJ_02916 1.43e-136 ytxB - - S - - - SNARE associated Golgi protein
EPKFIKFJ_02917 2.64e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
EPKFIKFJ_02918 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
EPKFIKFJ_02919 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPKFIKFJ_02920 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EPKFIKFJ_02921 4.24e-247 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPKFIKFJ_02922 7.74e-86 ytcD - - K - - - Transcriptional regulator
EPKFIKFJ_02923 3.31e-251 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
EPKFIKFJ_02924 4.68e-198 ytbE - - S - - - reductase
EPKFIKFJ_02925 3.15e-123 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPKFIKFJ_02926 4.52e-135 ytaF - - P - - - Probably functions as a manganese efflux pump
EPKFIKFJ_02927 2.14e-197 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EPKFIKFJ_02928 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPKFIKFJ_02929 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
EPKFIKFJ_02930 2.29e-164 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_02931 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
EPKFIKFJ_02932 1.54e-307 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
EPKFIKFJ_02933 8.21e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
EPKFIKFJ_02934 1.14e-95 ytwI - - S - - - membrane
EPKFIKFJ_02935 8.18e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
EPKFIKFJ_02936 1.34e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
EPKFIKFJ_02937 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
EPKFIKFJ_02938 1.33e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EPKFIKFJ_02939 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EPKFIKFJ_02940 2.08e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPKFIKFJ_02941 1.92e-283 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EPKFIKFJ_02942 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
EPKFIKFJ_02943 1.12e-71 ytrH - - S - - - Sporulation protein YtrH
EPKFIKFJ_02944 3.08e-113 ytrI - - - - - - -
EPKFIKFJ_02945 1.17e-30 - - - - - - - -
EPKFIKFJ_02946 7.37e-223 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
EPKFIKFJ_02947 3.44e-60 ytpI - - S - - - YtpI-like protein
EPKFIKFJ_02948 3.87e-303 ytoI - - K - - - transcriptional regulator containing CBS domains
EPKFIKFJ_02949 2.31e-163 ytkL - - S - - - Belongs to the UPF0173 family
EPKFIKFJ_02950 1.33e-180 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_02952 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
EPKFIKFJ_02953 8.67e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPKFIKFJ_02954 1.64e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
EPKFIKFJ_02955 2.6e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPKFIKFJ_02956 4.08e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EPKFIKFJ_02957 1.12e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPKFIKFJ_02958 1.37e-99 ytfJ - - S - - - Sporulation protein YtfJ
EPKFIKFJ_02959 3.61e-147 ytfI - - S - - - Protein of unknown function (DUF2953)
EPKFIKFJ_02960 1.31e-103 yteJ - - S - - - RDD family
EPKFIKFJ_02961 1.88e-227 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
EPKFIKFJ_02962 1.23e-191 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPKFIKFJ_02963 0.0 ytcJ - - S - - - amidohydrolase
EPKFIKFJ_02964 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EPKFIKFJ_02965 4.15e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
EPKFIKFJ_02966 1.06e-280 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPKFIKFJ_02967 3.99e-259 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
EPKFIKFJ_02968 4.41e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
EPKFIKFJ_02969 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EPKFIKFJ_02970 3.79e-183 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
EPKFIKFJ_02971 2.22e-137 yttP - - K - - - Transcriptional regulator
EPKFIKFJ_02972 2.38e-109 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
EPKFIKFJ_02973 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
EPKFIKFJ_02974 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPKFIKFJ_02975 1.22e-272 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPKFIKFJ_02978 0.000125 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
EPKFIKFJ_02980 1.52e-161 - - - E - - - GDSL-like Lipase/Acylhydrolase family
EPKFIKFJ_02981 6.5e-189 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPKFIKFJ_02982 1.06e-188 - - - K - - - Transcriptional regulator
EPKFIKFJ_02983 7.21e-154 ygaZ - - E - - - AzlC protein
EPKFIKFJ_02984 7.23e-63 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
EPKFIKFJ_02985 1.41e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPKFIKFJ_02986 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
EPKFIKFJ_02987 3.88e-153 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
EPKFIKFJ_02988 9.68e-138 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
EPKFIKFJ_02989 1.4e-283 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
EPKFIKFJ_02990 1.64e-143 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
EPKFIKFJ_02991 2.47e-184 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
EPKFIKFJ_02992 7.72e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
EPKFIKFJ_02993 1.8e-248 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
EPKFIKFJ_02994 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
EPKFIKFJ_02995 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
EPKFIKFJ_02996 2.16e-25 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EPKFIKFJ_02997 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
EPKFIKFJ_02998 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
EPKFIKFJ_02999 1.15e-136 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPKFIKFJ_03000 1.1e-186 ytpQ - - S - - - Belongs to the UPF0354 family
EPKFIKFJ_03001 2.23e-75 ytpP - - CO - - - Thioredoxin
EPKFIKFJ_03002 5.33e-98 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
EPKFIKFJ_03003 8.38e-258 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
EPKFIKFJ_03004 9.96e-69 ytzB - - S - - - small secreted protein
EPKFIKFJ_03005 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
EPKFIKFJ_03006 1.41e-204 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
EPKFIKFJ_03007 4.34e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPKFIKFJ_03008 4.54e-59 ytzH - - S - - - YtzH-like protein
EPKFIKFJ_03009 3.42e-198 ytmP - - M - - - Phosphotransferase
EPKFIKFJ_03010 1.86e-214 ytlR - - I - - - Diacylglycerol kinase catalytic domain
EPKFIKFJ_03011 2.86e-198 ytlQ - - - - - - -
EPKFIKFJ_03012 2.04e-128 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EPKFIKFJ_03013 4.05e-214 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
EPKFIKFJ_03014 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
EPKFIKFJ_03015 3.89e-286 pbuO - - S ko:K06901 - ko00000,ko02000 permease
EPKFIKFJ_03016 1.72e-251 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
EPKFIKFJ_03017 1.92e-149 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EPKFIKFJ_03018 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
EPKFIKFJ_03019 4.25e-160 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
EPKFIKFJ_03020 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKFIKFJ_03021 2.31e-293 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
EPKFIKFJ_03022 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
EPKFIKFJ_03023 3.57e-35 yteV - - S - - - Sporulation protein Cse60
EPKFIKFJ_03024 3.97e-232 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_03025 3.41e-296 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
EPKFIKFJ_03026 6.99e-212 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKFIKFJ_03027 1.37e-182 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EPKFIKFJ_03028 2.49e-313 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
EPKFIKFJ_03029 6.31e-96 - - - M - - - Acetyltransferase (GNAT) domain
EPKFIKFJ_03030 8.6e-69 ytwF - - P - - - Sulfurtransferase
EPKFIKFJ_03031 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
EPKFIKFJ_03032 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
EPKFIKFJ_03033 1.79e-172 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
EPKFIKFJ_03034 2.16e-265 yttB - - EGP - - - Major facilitator superfamily
EPKFIKFJ_03035 4.62e-130 ywaF - - S - - - Integral membrane protein
EPKFIKFJ_03036 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
EPKFIKFJ_03037 7.67e-171 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_03038 4.31e-206 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
EPKFIKFJ_03039 5.19e-157 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_03040 3.54e-258 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
EPKFIKFJ_03041 7.08e-160 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_03042 1.47e-190 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
EPKFIKFJ_03043 2.63e-203 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EPKFIKFJ_03044 2.23e-215 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EPKFIKFJ_03045 9.08e-202 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_03046 6.32e-86 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
EPKFIKFJ_03048 2.89e-52 ytzC - - S - - - Protein of unknown function (DUF2524)
EPKFIKFJ_03049 6.73e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
EPKFIKFJ_03050 4.07e-133 ytqB - - J - - - Putative rRNA methylase
EPKFIKFJ_03052 2.17e-266 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
EPKFIKFJ_03053 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
EPKFIKFJ_03054 7.46e-80 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EPKFIKFJ_03055 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKFIKFJ_03056 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
EPKFIKFJ_03057 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPKFIKFJ_03058 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EPKFIKFJ_03059 1.65e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
EPKFIKFJ_03060 6.15e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
EPKFIKFJ_03061 6.07e-228 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
EPKFIKFJ_03062 1.38e-180 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EPKFIKFJ_03063 3.42e-170 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
EPKFIKFJ_03064 5.86e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
EPKFIKFJ_03065 1.67e-77 ytkC - - S - - - Bacteriophage holin family
EPKFIKFJ_03066 3e-98 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EPKFIKFJ_03068 9.99e-98 ytkA - - S - - - YtkA-like
EPKFIKFJ_03069 5.89e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPKFIKFJ_03070 5.71e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
EPKFIKFJ_03071 4.26e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EPKFIKFJ_03072 7.13e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
EPKFIKFJ_03073 6.36e-313 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EPKFIKFJ_03074 9.63e-230 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
EPKFIKFJ_03075 3.88e-34 - - - S - - - Domain of Unknown Function (DUF1540)
EPKFIKFJ_03076 4.21e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EPKFIKFJ_03077 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EPKFIKFJ_03078 7.22e-198 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPKFIKFJ_03079 2.39e-188 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EPKFIKFJ_03080 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EPKFIKFJ_03081 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EPKFIKFJ_03082 8.57e-160 yteA - - T - - - COG1734 DnaK suppressor protein
EPKFIKFJ_03083 5.18e-93 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
EPKFIKFJ_03105 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
EPKFIKFJ_03106 3.55e-118 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
EPKFIKFJ_03107 1.38e-273 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
EPKFIKFJ_03108 7.32e-105 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
EPKFIKFJ_03109 1.42e-102 yuaE - - S - - - DinB superfamily
EPKFIKFJ_03110 1.21e-134 - - - S - - - MOSC domain
EPKFIKFJ_03111 9.64e-288 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
EPKFIKFJ_03112 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPKFIKFJ_03113 9.65e-119 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
EPKFIKFJ_03114 4.6e-119 yuaB - - - - - - -
EPKFIKFJ_03115 1.97e-152 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
EPKFIKFJ_03116 2.27e-185 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPKFIKFJ_03117 6.24e-268 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EPKFIKFJ_03118 2.36e-47 - - - G - - - Cupin
EPKFIKFJ_03119 2.17e-57 yjcN - - - - - - -
EPKFIKFJ_03122 2.15e-177 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
EPKFIKFJ_03123 7.36e-20 - - - - - - - -
EPKFIKFJ_03124 6.15e-129 - - - K - - - Helix-turn-helix domain
EPKFIKFJ_03127 2.65e-68 - - - - - - - -
EPKFIKFJ_03128 2.56e-46 - - - S - - - Bacteriophage A118-like holin, Hol118
EPKFIKFJ_03129 4.96e-186 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_03130 1.66e-39 - - - S - - - BhlA holin family
EPKFIKFJ_03133 2.79e-106 - - - - - - - -
EPKFIKFJ_03134 0.0 - - - M - - - Pectate lyase superfamily protein
EPKFIKFJ_03135 1.61e-234 - - - L - - - Prophage endopeptidase tail
EPKFIKFJ_03136 1.38e-138 - - - S - - - Phage tail protein
EPKFIKFJ_03137 2.91e-142 - - - D - - - Phage tail tape measure protein
EPKFIKFJ_03138 3.97e-44 - - - - - - - -
EPKFIKFJ_03139 1.05e-91 - - - N - - - phage major tail protein, phi13 family
EPKFIKFJ_03140 1.21e-32 - - - - - - - -
EPKFIKFJ_03142 4.52e-48 - - - S - - - Phage head-tail joining protein
EPKFIKFJ_03143 7.71e-34 - - - S - - - Phage gp6-like head-tail connector protein
EPKFIKFJ_03144 3.35e-53 - - - N - - - domain, Protein
EPKFIKFJ_03145 2.21e-230 - - - S - - - Phage capsid family
EPKFIKFJ_03146 4.02e-158 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
EPKFIKFJ_03147 2.45e-288 - - - S - - - Phage portal protein
EPKFIKFJ_03148 0.0 - - - S - - - Terminase
EPKFIKFJ_03149 1.71e-61 - - - L - - - Phage terminase, small subunit
EPKFIKFJ_03150 3.27e-41 - - - L ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
EPKFIKFJ_03151 1.67e-50 - - - - - - - -
EPKFIKFJ_03153 2.35e-45 - - - - - - - -
EPKFIKFJ_03155 2.41e-10 - - - - - - - -
EPKFIKFJ_03158 1.79e-49 - - GT2 S ko:K19425,ko:K19427 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKFIKFJ_03159 3.85e-39 - - - K - - - Cro/C1-type HTH DNA-binding domain
EPKFIKFJ_03160 3.86e-71 - - - S - - - Pfam:DUF867
EPKFIKFJ_03161 1.9e-141 - - - M - - - Right handed beta helix region
EPKFIKFJ_03165 3.77e-60 - - - - - - - -
EPKFIKFJ_03166 7.61e-32 - - - - - - - -
EPKFIKFJ_03168 1.46e-10 - - - - - - - -
EPKFIKFJ_03169 3.77e-44 - - - - - - - -
EPKFIKFJ_03170 3.88e-55 - - - K - - - Sigma-70, region 4
EPKFIKFJ_03171 1.71e-22 - - - S - - - sequence-specific DNA binding transcription factor activity
EPKFIKFJ_03173 8.7e-214 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
EPKFIKFJ_03174 3.58e-97 - - - H - - - dephospho-CoA kinase activity
EPKFIKFJ_03175 4.14e-48 - - - - - - - -
EPKFIKFJ_03177 1.09e-42 - - - S - - - protein conserved in bacteria
EPKFIKFJ_03178 1.67e-126 - 2.1.1.148 - F ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 ko00000,ko00001,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
EPKFIKFJ_03180 1.01e-72 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 deoxyuridine 5'-triphosphate nucleotidohydrolase
EPKFIKFJ_03182 6.57e-193 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPKFIKFJ_03184 4.16e-228 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPKFIKFJ_03185 0.000318 - - - S - - - Transcriptional regulator
EPKFIKFJ_03186 2.78e-151 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPKFIKFJ_03187 2.45e-57 - - - F - - - Belongs to the NrdI family
EPKFIKFJ_03191 6.96e-21 - 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Crossover junction endodeoxyribonuclease RuvC
EPKFIKFJ_03193 2.94e-209 - - - - - - - -
EPKFIKFJ_03194 6.41e-132 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
EPKFIKFJ_03195 2.14e-244 - - - L - - - DNA polymerase A domain
EPKFIKFJ_03197 1.36e-20 - - - - - - - -
EPKFIKFJ_03198 1.77e-62 - - - - - - - -
EPKFIKFJ_03199 1.9e-102 - - - - - - - -
EPKFIKFJ_03205 1.96e-68 - - - - - - - -
EPKFIKFJ_03207 6.38e-163 - - - L - - - Toprim-like
EPKFIKFJ_03208 1.31e-175 - - - L - - - DnaB-like helicase C terminal domain
EPKFIKFJ_03211 3.62e-138 - - - L ko:K02315 - ko00000,ko03032 DNA-dependent DNA replication
EPKFIKFJ_03214 2.21e-78 - - - - - - - -
EPKFIKFJ_03216 5.22e-33 - - - - - - - -
EPKFIKFJ_03218 3e-50 - - - S - - - Helix-turn-helix domain
EPKFIKFJ_03220 1.11e-108 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
EPKFIKFJ_03222 7.33e-184 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EPKFIKFJ_03223 2.73e-248 yubA - - S - - - transporter activity
EPKFIKFJ_03224 4.84e-231 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EPKFIKFJ_03225 4.02e-126 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
EPKFIKFJ_03226 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKFIKFJ_03227 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKFIKFJ_03228 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKFIKFJ_03229 4.49e-285 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
EPKFIKFJ_03230 1.68e-174 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
EPKFIKFJ_03231 1.82e-52 - - - - - - - -
EPKFIKFJ_03232 5.54e-236 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
EPKFIKFJ_03233 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
EPKFIKFJ_03234 1.82e-293 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
EPKFIKFJ_03235 1.95e-149 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
EPKFIKFJ_03236 3.56e-22 - - - - - - - -
EPKFIKFJ_03237 2.98e-36 mstX - - S - - - Membrane-integrating protein Mistic
EPKFIKFJ_03238 8.97e-227 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
EPKFIKFJ_03239 4.57e-90 yugN - - S - - - YugN-like family
EPKFIKFJ_03241 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
EPKFIKFJ_03242 8.85e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
EPKFIKFJ_03243 7.5e-283 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
EPKFIKFJ_03244 1.28e-45 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
EPKFIKFJ_03245 8.3e-82 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
EPKFIKFJ_03246 2.28e-264 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
EPKFIKFJ_03247 1.53e-108 alaR - - K - - - Transcriptional regulator
EPKFIKFJ_03248 3.41e-192 yugF - - I - - - Hydrolase
EPKFIKFJ_03249 3.95e-51 yugE - - S - - - Domain of unknown function (DUF1871)
EPKFIKFJ_03250 1.89e-276 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EPKFIKFJ_03251 5e-278 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_03252 4.14e-81 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
EPKFIKFJ_03253 7.29e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
EPKFIKFJ_03254 2.6e-240 yuxJ - - EGP - - - Major facilitator superfamily
EPKFIKFJ_03255 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
EPKFIKFJ_03256 5.95e-92 yuxK - - S - - - protein conserved in bacteria
EPKFIKFJ_03257 2.08e-97 yufK - - S - - - Family of unknown function (DUF5366)
EPKFIKFJ_03258 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
EPKFIKFJ_03259 3.8e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
EPKFIKFJ_03260 7.9e-247 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
EPKFIKFJ_03261 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_03262 1.68e-232 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EPKFIKFJ_03263 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EPKFIKFJ_03265 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
EPKFIKFJ_03266 8.6e-88 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKFIKFJ_03267 1.42e-65 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKFIKFJ_03268 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKFIKFJ_03269 1.13e-97 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKFIKFJ_03270 2.15e-49 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
EPKFIKFJ_03271 8.16e-77 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
EPKFIKFJ_03272 3.55e-77 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
EPKFIKFJ_03273 3.29e-147 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKFIKFJ_03274 1.19e-315 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_03276 5.91e-78 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
EPKFIKFJ_03277 1.87e-11 - - - S - - - DegQ (SacQ) family
EPKFIKFJ_03278 1.59e-62 yuzC - - - - - - -
EPKFIKFJ_03279 1.12e-285 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
EPKFIKFJ_03280 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPKFIKFJ_03281 4.46e-132 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
EPKFIKFJ_03282 4.96e-86 yueI - - S - - - Protein of unknown function (DUF1694)
EPKFIKFJ_03283 1.1e-50 yueH - - S - - - YueH-like protein
EPKFIKFJ_03284 4.3e-44 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
EPKFIKFJ_03285 2.31e-232 yueF - - S - - - transporter activity
EPKFIKFJ_03286 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
EPKFIKFJ_03287 1.83e-123 yueE - - S ko:K06950 - ko00000 phosphohydrolase
EPKFIKFJ_03288 2.35e-159 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_03289 4.27e-97 yueC - - S - - - Family of unknown function (DUF5383)
EPKFIKFJ_03290 0.0 yueB - - S - - - type VII secretion protein EsaA
EPKFIKFJ_03291 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
EPKFIKFJ_03292 2.45e-261 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
EPKFIKFJ_03293 8.78e-52 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
EPKFIKFJ_03294 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
EPKFIKFJ_03295 1.66e-288 yukF - - QT - - - Transcriptional regulator
EPKFIKFJ_03296 9.05e-258 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
EPKFIKFJ_03297 2.71e-165 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
EPKFIKFJ_03298 3.6e-42 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
EPKFIKFJ_03299 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_03300 5.68e-208 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
EPKFIKFJ_03301 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
EPKFIKFJ_03302 7.09e-273 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
EPKFIKFJ_03303 5.34e-166 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKFIKFJ_03304 2.31e-198 eSD - - S ko:K07017 - ko00000 Putative esterase
EPKFIKFJ_03305 1.8e-152 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
EPKFIKFJ_03306 4.35e-130 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
EPKFIKFJ_03307 1.11e-273 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
EPKFIKFJ_03308 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EPKFIKFJ_03309 1.37e-98 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
EPKFIKFJ_03310 2.23e-149 yuiC - - S - - - protein conserved in bacteria
EPKFIKFJ_03311 1.21e-45 yuiB - - S - - - Putative membrane protein
EPKFIKFJ_03312 3.83e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EPKFIKFJ_03313 1.15e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
EPKFIKFJ_03315 1.29e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPKFIKFJ_03316 1.57e-37 - - - - - - - -
EPKFIKFJ_03317 1.09e-86 - - - CP - - - Membrane
EPKFIKFJ_03318 1.41e-151 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
EPKFIKFJ_03320 1.12e-37 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
EPKFIKFJ_03322 5.08e-55 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
EPKFIKFJ_03323 6e-167 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKFIKFJ_03324 1.88e-80 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
EPKFIKFJ_03325 1.46e-203 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPKFIKFJ_03326 2.57e-272 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPKFIKFJ_03327 4.81e-50 yuzB - - S - - - Belongs to the UPF0349 family
EPKFIKFJ_03328 7.79e-262 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
EPKFIKFJ_03329 2.61e-70 yuzD - - S - - - protein conserved in bacteria
EPKFIKFJ_03330 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
EPKFIKFJ_03331 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EPKFIKFJ_03332 1.55e-70 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
EPKFIKFJ_03333 2.22e-206 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPKFIKFJ_03334 3.65e-248 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EPKFIKFJ_03335 1.37e-306 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
EPKFIKFJ_03336 5.56e-244 yutH - - S - - - Spore coat protein
EPKFIKFJ_03337 3.6e-107 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
EPKFIKFJ_03338 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EPKFIKFJ_03339 3e-93 yutE - - S - - - Protein of unknown function DUF86
EPKFIKFJ_03340 3.71e-62 yutD - - S - - - protein conserved in bacteria
EPKFIKFJ_03341 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EPKFIKFJ_03342 1.26e-245 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
EPKFIKFJ_03343 1.53e-164 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
EPKFIKFJ_03344 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
EPKFIKFJ_03345 5.58e-182 yunE - - S ko:K07090 - ko00000 membrane transporter protein
EPKFIKFJ_03346 7.05e-215 yunF - - S - - - Protein of unknown function DUF72
EPKFIKFJ_03347 2.23e-73 - - - S - - - phosphoglycolate phosphatase activity
EPKFIKFJ_03348 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
EPKFIKFJ_03349 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
EPKFIKFJ_03350 6.3e-86 - - - - - - - -
EPKFIKFJ_03351 8.83e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_03352 2.55e-287 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
EPKFIKFJ_03353 7.27e-285 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
EPKFIKFJ_03354 3.33e-209 bsn - - L - - - Ribonuclease
EPKFIKFJ_03355 1.49e-252 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_03356 8.02e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
EPKFIKFJ_03357 6.94e-202 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
EPKFIKFJ_03358 2.91e-199 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
EPKFIKFJ_03359 7.16e-201 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKFIKFJ_03360 4.58e-305 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
EPKFIKFJ_03361 8.37e-232 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
EPKFIKFJ_03362 8.02e-204 - - - K - - - helix_turn_helix, mercury resistance
EPKFIKFJ_03364 1.34e-95 - - - - - - - -
EPKFIKFJ_03365 1.96e-27 - - - S - - - Sporulation delaying protein SdpA
EPKFIKFJ_03367 1.36e-84 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
EPKFIKFJ_03368 2.19e-251 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
EPKFIKFJ_03369 1.09e-128 - - - Q - - - ubiE/COQ5 methyltransferase family
EPKFIKFJ_03370 7.45e-94 yncE - - S - - - Protein of unknown function (DUF2691)
EPKFIKFJ_03371 1.06e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
EPKFIKFJ_03372 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
EPKFIKFJ_03373 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
EPKFIKFJ_03374 3.01e-294 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPKFIKFJ_03375 1.75e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
EPKFIKFJ_03376 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EPKFIKFJ_03378 2.97e-83 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EPKFIKFJ_03379 2.88e-183 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
EPKFIKFJ_03380 3.3e-135 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
EPKFIKFJ_03381 1.51e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPKFIKFJ_03382 5.08e-74 yusD - - S - - - SCP-2 sterol transfer family
EPKFIKFJ_03383 2.25e-70 yusE - - CO - - - Thioredoxin
EPKFIKFJ_03384 5.93e-30 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
EPKFIKFJ_03385 2.99e-53 yusG - - S - - - Protein of unknown function (DUF2553)
EPKFIKFJ_03386 1.19e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
EPKFIKFJ_03387 4.13e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
EPKFIKFJ_03388 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
EPKFIKFJ_03389 3.02e-275 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
EPKFIKFJ_03390 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
EPKFIKFJ_03391 1.72e-10 - - - S - - - YuzL-like protein
EPKFIKFJ_03392 6.69e-209 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
EPKFIKFJ_03393 7.03e-53 - - - - - - - -
EPKFIKFJ_03394 3.53e-69 yusN - - M - - - Coat F domain
EPKFIKFJ_03395 1.47e-86 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
EPKFIKFJ_03396 0.0 yusP - - P - - - Major facilitator superfamily
EPKFIKFJ_03397 6.56e-74 - - - L - - - PFAM Restriction endonuclease BamHI
EPKFIKFJ_03398 1.48e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
EPKFIKFJ_03399 3.73e-159 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
EPKFIKFJ_03400 1.46e-50 yusU - - S - - - Protein of unknown function (DUF2573)
EPKFIKFJ_03401 1.06e-191 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EPKFIKFJ_03402 2.79e-62 - - - S - - - YusW-like protein
EPKFIKFJ_03403 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
EPKFIKFJ_03404 1.77e-177 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKFIKFJ_03405 5.63e-101 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
EPKFIKFJ_03406 8.65e-295 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKFIKFJ_03407 2.06e-160 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_03408 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_03409 2.68e-32 - - - - - - - -
EPKFIKFJ_03410 6.7e-196 yuxN - - K - - - Transcriptional regulator
EPKFIKFJ_03411 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EPKFIKFJ_03412 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
EPKFIKFJ_03413 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EPKFIKFJ_03414 3e-235 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EPKFIKFJ_03415 9.22e-248 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
EPKFIKFJ_03416 8.35e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKFIKFJ_03417 2.86e-246 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_03418 6.74e-159 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
EPKFIKFJ_03419 1.33e-165 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
EPKFIKFJ_03420 6e-128 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
EPKFIKFJ_03421 7.39e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
EPKFIKFJ_03422 9.45e-281 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_03423 3.89e-125 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
EPKFIKFJ_03424 5.35e-257 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
EPKFIKFJ_03425 5.73e-224 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_03426 1.07e-211 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
EPKFIKFJ_03427 4.79e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKFIKFJ_03428 2.36e-213 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
EPKFIKFJ_03429 0.0 yvrG - - T - - - Histidine kinase
EPKFIKFJ_03430 4.48e-171 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_03431 1.14e-48 - - - - - - - -
EPKFIKFJ_03432 1.47e-130 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
EPKFIKFJ_03433 1.88e-21 - - - S - - - YvrJ protein family
EPKFIKFJ_03434 9.98e-292 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
EPKFIKFJ_03435 1.37e-78 yvrL - - S - - - Regulatory protein YrvL
EPKFIKFJ_03436 6.61e-187 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
EPKFIKFJ_03437 9.44e-217 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_03438 6.08e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_03439 2.12e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
EPKFIKFJ_03440 2.17e-153 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EPKFIKFJ_03441 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
EPKFIKFJ_03442 4.34e-19 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
EPKFIKFJ_03443 2.04e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
EPKFIKFJ_03444 3.8e-210 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EPKFIKFJ_03445 2.24e-203 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
EPKFIKFJ_03446 8.02e-204 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
EPKFIKFJ_03447 4.92e-174 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
EPKFIKFJ_03448 1.21e-128 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
EPKFIKFJ_03449 2.17e-146 yfiK - - K - - - Regulator
EPKFIKFJ_03450 3.01e-237 - - - T - - - Histidine kinase
EPKFIKFJ_03451 1.12e-216 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
EPKFIKFJ_03452 3.65e-235 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
EPKFIKFJ_03453 1.44e-229 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
EPKFIKFJ_03454 1.77e-200 yvgN - - S - - - reductase
EPKFIKFJ_03455 1.55e-110 yvgO - - - - - - -
EPKFIKFJ_03456 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
EPKFIKFJ_03457 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
EPKFIKFJ_03458 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EPKFIKFJ_03459 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
EPKFIKFJ_03461 6.1e-128 yvgT - - S - - - membrane
EPKFIKFJ_03462 5.24e-188 - - - S - - - Metallo-peptidase family M12
EPKFIKFJ_03463 5.06e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
EPKFIKFJ_03464 2.51e-135 bdbD - - O - - - Thioredoxin
EPKFIKFJ_03465 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
EPKFIKFJ_03466 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
EPKFIKFJ_03467 9.29e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
EPKFIKFJ_03468 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
EPKFIKFJ_03469 4.69e-238 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
EPKFIKFJ_03470 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EPKFIKFJ_03471 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKFIKFJ_03472 1.97e-59 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
EPKFIKFJ_03473 7.09e-226 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKFIKFJ_03474 3.93e-175 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
EPKFIKFJ_03475 5.33e-152 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKFIKFJ_03476 1.35e-152 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
EPKFIKFJ_03477 1.8e-181 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EPKFIKFJ_03478 3.28e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
EPKFIKFJ_03479 5.25e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
EPKFIKFJ_03480 4.27e-201 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
EPKFIKFJ_03481 1.18e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
EPKFIKFJ_03482 9.41e-56 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
EPKFIKFJ_03484 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EPKFIKFJ_03485 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EPKFIKFJ_03486 6.92e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
EPKFIKFJ_03487 9.24e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
EPKFIKFJ_03488 1.64e-47 yvzC - - K - - - transcriptional
EPKFIKFJ_03489 1.07e-89 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
EPKFIKFJ_03490 1.09e-90 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
EPKFIKFJ_03491 1.17e-67 yvaP - - K - - - transcriptional
EPKFIKFJ_03492 3.51e-308 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
EPKFIKFJ_03493 7.17e-154 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
EPKFIKFJ_03494 4.95e-170 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EPKFIKFJ_03495 1.91e-154 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
EPKFIKFJ_03496 1.27e-160 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_03497 1.41e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKFIKFJ_03498 5.17e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EPKFIKFJ_03499 7.36e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKFIKFJ_03500 1.25e-262 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EPKFIKFJ_03501 3.5e-108 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EPKFIKFJ_03502 2.95e-139 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKFIKFJ_03503 2.99e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
EPKFIKFJ_03504 5.4e-143 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
EPKFIKFJ_03505 1.21e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
EPKFIKFJ_03506 2.67e-125 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
EPKFIKFJ_03507 1.55e-134 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
EPKFIKFJ_03508 2.61e-148 yvbI - - M - - - Membrane
EPKFIKFJ_03509 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
EPKFIKFJ_03510 5.07e-103 yvbK - - K - - - acetyltransferase
EPKFIKFJ_03511 4.16e-260 - - - EGP - - - Major facilitator Superfamily
EPKFIKFJ_03512 1.87e-219 - - - - - - - -
EPKFIKFJ_03513 3.54e-159 - - - S - - - GlcNAc-PI de-N-acetylase
EPKFIKFJ_03514 1.13e-182 - - - C - - - WbqC-like protein family
EPKFIKFJ_03515 2.49e-179 - - - M - - - Protein involved in cellulose biosynthesis
EPKFIKFJ_03516 6.62e-279 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EPKFIKFJ_03517 6.48e-215 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
EPKFIKFJ_03518 2.68e-275 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EPKFIKFJ_03519 9.36e-317 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPKFIKFJ_03520 2.83e-286 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
EPKFIKFJ_03521 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPKFIKFJ_03522 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
EPKFIKFJ_03523 1.49e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPKFIKFJ_03524 1.55e-274 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
EPKFIKFJ_03525 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPKFIKFJ_03526 1.91e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EPKFIKFJ_03528 4.6e-272 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKFIKFJ_03529 1.76e-257 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
EPKFIKFJ_03530 1.78e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKFIKFJ_03531 3.86e-18 yvbU - - K - - - Transcriptional regulator
EPKFIKFJ_03532 2.18e-124 yvbU - - K - - - Transcriptional regulator
EPKFIKFJ_03533 5.35e-196 yvbV - - EG - - - EamA-like transporter family
EPKFIKFJ_03534 6.69e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKFIKFJ_03536 2.88e-190 gntR - - K - - - RpiR family transcriptional regulator
EPKFIKFJ_03537 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
EPKFIKFJ_03538 3.08e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
EPKFIKFJ_03539 3.12e-167 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EPKFIKFJ_03540 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
EPKFIKFJ_03541 1.69e-170 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
EPKFIKFJ_03542 2.07e-264 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EPKFIKFJ_03543 1.16e-151 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
EPKFIKFJ_03544 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
EPKFIKFJ_03545 1.61e-293 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
EPKFIKFJ_03546 4.01e-44 yvfG - - S - - - YvfG protein
EPKFIKFJ_03547 2.77e-224 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
EPKFIKFJ_03548 2.79e-275 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
EPKFIKFJ_03549 1.28e-70 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EPKFIKFJ_03550 2.7e-131 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EPKFIKFJ_03551 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKFIKFJ_03552 1.99e-238 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKFIKFJ_03553 6.55e-251 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
EPKFIKFJ_03554 6.01e-245 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EPKFIKFJ_03555 6.38e-258 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
EPKFIKFJ_03556 1.95e-253 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
EPKFIKFJ_03557 3.44e-200 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
EPKFIKFJ_03558 4.24e-269 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
EPKFIKFJ_03559 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EPKFIKFJ_03560 4.44e-151 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EPKFIKFJ_03561 4.37e-151 epsA - - M ko:K19420 - ko00000 biosynthesis protein
EPKFIKFJ_03562 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
EPKFIKFJ_03563 8.66e-312 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
EPKFIKFJ_03565 8.3e-111 ywjB - - H - - - RibD C-terminal domain
EPKFIKFJ_03566 4.2e-164 - - - CH - - - FAD binding domain
EPKFIKFJ_03567 2.74e-98 glx2 - - S - - - Metallo-beta-lactamase superfamily
EPKFIKFJ_03568 5.22e-137 yyaS - - S ko:K07149 - ko00000 Membrane
EPKFIKFJ_03569 3.65e-108 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPKFIKFJ_03570 7.09e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
EPKFIKFJ_03571 1.25e-63 - - - S - - - Protein of unknown function (DUF3237)
EPKFIKFJ_03572 3.4e-43 - - - S - - - Protein of unknown function (DUF1433)
EPKFIKFJ_03573 1.63e-30 - - - S - - - Protein of unknown function (DUF1433)
EPKFIKFJ_03574 6.57e-25 - - - S - - - Protein of unknown function (DUF1433)
EPKFIKFJ_03575 0.0 - - - I - - - Pfam Lipase (class 3)
EPKFIKFJ_03576 3.08e-44 - - - - - - - -
EPKFIKFJ_03578 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EPKFIKFJ_03579 5.05e-279 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
EPKFIKFJ_03580 2.68e-226 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
EPKFIKFJ_03581 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPKFIKFJ_03582 1.4e-202 yraN - - K - - - Transcriptional regulator
EPKFIKFJ_03583 3.16e-258 yraM - - S - - - PrpF protein
EPKFIKFJ_03584 6.64e-313 - - - EGP - - - Sugar (and other) transporter
EPKFIKFJ_03585 1.06e-110 - - - - - - - -
EPKFIKFJ_03586 2.87e-132 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
EPKFIKFJ_03587 5.98e-66 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
EPKFIKFJ_03588 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
EPKFIKFJ_03589 8.55e-135 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
EPKFIKFJ_03590 7.72e-229 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPKFIKFJ_03591 4.11e-100 - - - M - - - Ribonuclease
EPKFIKFJ_03592 5.8e-167 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
EPKFIKFJ_03593 6.52e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
EPKFIKFJ_03594 1.48e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
EPKFIKFJ_03595 3.01e-224 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
EPKFIKFJ_03596 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
EPKFIKFJ_03597 7.32e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
EPKFIKFJ_03598 6.06e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPKFIKFJ_03599 7.8e-192 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
EPKFIKFJ_03600 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
EPKFIKFJ_03601 1.01e-231 sasA - - T - - - Histidine kinase
EPKFIKFJ_03602 1.49e-153 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_03603 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
EPKFIKFJ_03604 8.74e-139 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
EPKFIKFJ_03605 4.63e-175 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPKFIKFJ_03606 6.02e-163 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EPKFIKFJ_03607 1.75e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPKFIKFJ_03608 6.49e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
EPKFIKFJ_03609 4.77e-279 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPKFIKFJ_03610 1.45e-145 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EPKFIKFJ_03611 8.64e-258 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EPKFIKFJ_03612 3.83e-173 yvpB - - NU - - - protein conserved in bacteria
EPKFIKFJ_03613 1.2e-110 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
EPKFIKFJ_03614 3.18e-155 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
EPKFIKFJ_03615 5.06e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPKFIKFJ_03616 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EPKFIKFJ_03617 2.47e-272 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
EPKFIKFJ_03618 1.44e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPKFIKFJ_03619 2.9e-169 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
EPKFIKFJ_03620 6.76e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
EPKFIKFJ_03621 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
EPKFIKFJ_03622 1.09e-65 yvlD - - S ko:K08972 - ko00000 Membrane
EPKFIKFJ_03623 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
EPKFIKFJ_03624 4.14e-214 yvlB - - S - - - Putative adhesin
EPKFIKFJ_03625 1.79e-61 yvlA - - - - - - -
EPKFIKFJ_03626 1.29e-40 yvkN - - - - - - -
EPKFIKFJ_03627 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPKFIKFJ_03628 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPKFIKFJ_03629 2.59e-45 csbA - - S - - - protein conserved in bacteria
EPKFIKFJ_03630 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EPKFIKFJ_03631 1.02e-154 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
EPKFIKFJ_03632 1.12e-119 yvkB - - K - - - Transcriptional regulator
EPKFIKFJ_03633 3.49e-290 yvkA - - P - - - -transporter
EPKFIKFJ_03636 1.39e-278 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKFIKFJ_03637 5.83e-72 swrA - - S - - - Swarming motility protein
EPKFIKFJ_03638 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
EPKFIKFJ_03639 1.35e-271 ywoF - - P - - - Right handed beta helix region
EPKFIKFJ_03640 1.48e-196 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EPKFIKFJ_03641 3.53e-158 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
EPKFIKFJ_03642 1.47e-58 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
EPKFIKFJ_03643 5.39e-189 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKFIKFJ_03644 1.08e-222 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPKFIKFJ_03645 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPKFIKFJ_03646 4.25e-130 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPKFIKFJ_03647 1.92e-89 - - - - - - - -
EPKFIKFJ_03648 1.57e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
EPKFIKFJ_03649 2.18e-83 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
EPKFIKFJ_03650 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EPKFIKFJ_03651 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EPKFIKFJ_03652 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EPKFIKFJ_03653 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
EPKFIKFJ_03654 1.27e-104 yviE - - - - - - -
EPKFIKFJ_03655 1.63e-206 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
EPKFIKFJ_03656 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
EPKFIKFJ_03657 1.43e-101 yvyG - - NOU - - - FlgN protein
EPKFIKFJ_03658 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
EPKFIKFJ_03659 6.15e-95 yvyF - - S - - - flagellar protein
EPKFIKFJ_03660 4.91e-79 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
EPKFIKFJ_03661 2.93e-56 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
EPKFIKFJ_03662 5.41e-316 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EPKFIKFJ_03663 3.16e-197 degV - - S - - - protein conserved in bacteria
EPKFIKFJ_03664 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKFIKFJ_03665 2.31e-245 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
EPKFIKFJ_03666 1.1e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
EPKFIKFJ_03667 9.24e-234 yvhJ - - K - - - Transcriptional regulator
EPKFIKFJ_03668 8.94e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
EPKFIKFJ_03669 4.55e-285 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
EPKFIKFJ_03670 2.22e-182 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
EPKFIKFJ_03671 8.08e-138 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
EPKFIKFJ_03672 8.4e-317 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
EPKFIKFJ_03673 5.86e-310 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPKFIKFJ_03674 2.76e-270 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
EPKFIKFJ_03675 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
EPKFIKFJ_03676 8.51e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
EPKFIKFJ_03677 4.43e-268 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
EPKFIKFJ_03678 0.0 lytB - - D - - - Stage II sporulation protein
EPKFIKFJ_03679 1.99e-39 - - - - - - - -
EPKFIKFJ_03680 1.15e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
EPKFIKFJ_03681 8.48e-235 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EPKFIKFJ_03682 2.14e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
EPKFIKFJ_03683 1.55e-241 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EPKFIKFJ_03684 7.77e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
EPKFIKFJ_03685 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPKFIKFJ_03686 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
EPKFIKFJ_03687 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
EPKFIKFJ_03688 6.85e-179 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
EPKFIKFJ_03689 5.65e-258 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
EPKFIKFJ_03690 2.3e-290 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPKFIKFJ_03691 9.82e-234 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EPKFIKFJ_03692 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
EPKFIKFJ_03693 2.94e-243 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
EPKFIKFJ_03694 3.1e-218 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
EPKFIKFJ_03695 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
EPKFIKFJ_03696 9.98e-304 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKFIKFJ_03697 2.02e-223 ywtF_2 - - K - - - Transcriptional regulator
EPKFIKFJ_03698 1.33e-195 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EPKFIKFJ_03699 1.4e-60 yttA - - S - - - Pfam Transposase IS66
EPKFIKFJ_03700 1.37e-288 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
EPKFIKFJ_03701 2.34e-28 ywtC - - - - - - -
EPKFIKFJ_03702 7.41e-276 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
EPKFIKFJ_03703 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
EPKFIKFJ_03704 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
EPKFIKFJ_03705 1.63e-244 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
EPKFIKFJ_03706 6.95e-228 - - - E - - - Spore germination protein
EPKFIKFJ_03707 3.22e-63 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
EPKFIKFJ_03708 4.74e-144 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
EPKFIKFJ_03709 1.08e-221 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
EPKFIKFJ_03710 2.47e-195 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPKFIKFJ_03711 3.79e-83 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EPKFIKFJ_03712 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
EPKFIKFJ_03713 7.29e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
EPKFIKFJ_03714 7.75e-205 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
EPKFIKFJ_03715 6.3e-111 batE - - T - - - Sh3 type 3 domain protein
EPKFIKFJ_03716 2.39e-115 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
EPKFIKFJ_03717 3.56e-185 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
EPKFIKFJ_03718 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
EPKFIKFJ_03719 6.98e-211 alsR - - K - - - LysR substrate binding domain
EPKFIKFJ_03720 5.9e-297 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPKFIKFJ_03721 8.96e-150 ywrJ - - - - - - -
EPKFIKFJ_03722 4.38e-157 cotB - - - ko:K06325 - ko00000 -
EPKFIKFJ_03723 9.11e-261 cotH - - M ko:K06330 - ko00000 Spore Coat
EPKFIKFJ_03724 3.88e-09 - - - - - - - -
EPKFIKFJ_03725 4.7e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EPKFIKFJ_03727 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
EPKFIKFJ_03728 3.97e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
EPKFIKFJ_03729 7.48e-126 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
EPKFIKFJ_03730 2.03e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
EPKFIKFJ_03731 1.29e-130 - - - - - - - -
EPKFIKFJ_03732 7.15e-83 - - - - - - - -
EPKFIKFJ_03733 3.77e-97 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
EPKFIKFJ_03734 1.92e-25 - - - - - - - -
EPKFIKFJ_03735 2.19e-75 - - - S - - - SUKH-4 immunity protein
EPKFIKFJ_03736 2.69e-288 ywqJ - - S - - - Pre-toxin TG
EPKFIKFJ_03737 1.36e-48 ywqI - - S - - - Family of unknown function (DUF5344)
EPKFIKFJ_03739 3.03e-183 ywqG - - S - - - Domain of unknown function (DUF1963)
EPKFIKFJ_03740 2.45e-304 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EPKFIKFJ_03741 4.63e-176 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
EPKFIKFJ_03742 3.37e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
EPKFIKFJ_03743 8.45e-144 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
EPKFIKFJ_03744 3e-22 - - - - - - - -
EPKFIKFJ_03745 0.0 ywqB - - S - - - SWIM zinc finger
EPKFIKFJ_03746 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
EPKFIKFJ_03747 1.28e-193 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
EPKFIKFJ_03748 5.39e-178 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
EPKFIKFJ_03749 4.94e-75 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
EPKFIKFJ_03750 1.83e-74 ywpG - - - - - - -
EPKFIKFJ_03751 1.79e-89 ywpF - - S - - - YwpF-like protein
EPKFIKFJ_03752 2.54e-72 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPKFIKFJ_03753 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPKFIKFJ_03754 4.41e-247 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
EPKFIKFJ_03755 5.1e-176 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EPKFIKFJ_03756 1.16e-170 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
EPKFIKFJ_03757 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
EPKFIKFJ_03758 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
EPKFIKFJ_03759 5.3e-93 ywoH - - K - - - transcriptional
EPKFIKFJ_03760 3.92e-270 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
EPKFIKFJ_03761 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
EPKFIKFJ_03762 1.81e-308 ywoD - - EGP - - - Major facilitator superfamily
EPKFIKFJ_03763 2.1e-128 yjgF - - Q - - - Isochorismatase family
EPKFIKFJ_03764 3.63e-289 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
EPKFIKFJ_03765 1.51e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
EPKFIKFJ_03766 1.11e-262 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
EPKFIKFJ_03767 5.56e-130 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
EPKFIKFJ_03768 3.41e-88 ywnJ - - S - - - VanZ like family
EPKFIKFJ_03769 1.67e-175 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
EPKFIKFJ_03770 7.6e-113 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
EPKFIKFJ_03772 2.45e-88 ywnF - - S - - - Family of unknown function (DUF5392)
EPKFIKFJ_03773 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPKFIKFJ_03774 1.12e-21 yqgA - - - - - - -
EPKFIKFJ_03775 1.33e-77 ywnC - - S - - - Family of unknown function (DUF5362)
EPKFIKFJ_03776 3.75e-116 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
EPKFIKFJ_03777 3.09e-88 ywnA - - K - - - Transcriptional regulator
EPKFIKFJ_03778 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EPKFIKFJ_03779 4.37e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
EPKFIKFJ_03780 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
EPKFIKFJ_03781 2.21e-15 csbD - - K - - - CsbD-like
EPKFIKFJ_03782 1.01e-105 ywmF - - S - - - Peptidase M50
EPKFIKFJ_03783 1.44e-114 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKFIKFJ_03784 2.09e-243 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EPKFIKFJ_03785 2.91e-183 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EPKFIKFJ_03787 2.79e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EPKFIKFJ_03788 4.74e-145 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
EPKFIKFJ_03789 6.86e-232 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
EPKFIKFJ_03790 1.85e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPKFIKFJ_03791 1.27e-169 ywmB - - S - - - TATA-box binding
EPKFIKFJ_03792 1.85e-44 ywzB - - S - - - membrane
EPKFIKFJ_03793 1.98e-115 ywmA - - - - - - -
EPKFIKFJ_03794 3.36e-82 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
EPKFIKFJ_03795 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPKFIKFJ_03796 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPKFIKFJ_03797 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPKFIKFJ_03798 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPKFIKFJ_03799 3.35e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPKFIKFJ_03800 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPKFIKFJ_03801 5.19e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
EPKFIKFJ_03802 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
EPKFIKFJ_03803 1.3e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPKFIKFJ_03804 5.69e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPKFIKFJ_03805 3.53e-123 ywlG - - S - - - Belongs to the UPF0340 family
EPKFIKFJ_03806 9.2e-104 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
EPKFIKFJ_03807 1.84e-95 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPKFIKFJ_03808 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
EPKFIKFJ_03809 1.34e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EPKFIKFJ_03810 6.75e-96 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
EPKFIKFJ_03811 7.05e-148 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
EPKFIKFJ_03812 4.04e-77 ywlA - - S - - - Uncharacterised protein family (UPF0715)
EPKFIKFJ_03814 1.18e-194 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPKFIKFJ_03815 8.38e-240 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPKFIKFJ_03816 2.93e-85 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKFIKFJ_03817 2.52e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
EPKFIKFJ_03818 6.87e-194 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
EPKFIKFJ_03819 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
EPKFIKFJ_03820 6.49e-131 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
EPKFIKFJ_03821 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
EPKFIKFJ_03822 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPKFIKFJ_03823 9.65e-223 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
EPKFIKFJ_03824 1.59e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPKFIKFJ_03825 3.69e-143 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPKFIKFJ_03826 4.53e-203 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
EPKFIKFJ_03827 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
EPKFIKFJ_03828 1.84e-117 ywjG - - S - - - Domain of unknown function (DUF2529)
EPKFIKFJ_03829 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPKFIKFJ_03830 1.53e-71 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EPKFIKFJ_03831 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
EPKFIKFJ_03832 1.51e-263 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
EPKFIKFJ_03833 5.39e-224 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
EPKFIKFJ_03834 3.23e-58 ywjC - - - - - - -
EPKFIKFJ_03835 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
EPKFIKFJ_03836 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPKFIKFJ_03837 1.61e-149 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
EPKFIKFJ_03838 1.07e-110 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
EPKFIKFJ_03839 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
EPKFIKFJ_03840 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPKFIKFJ_03841 8.63e-102 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
EPKFIKFJ_03842 8.59e-162 ywiC - - S - - - YwiC-like protein
EPKFIKFJ_03843 5.83e-162 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
EPKFIKFJ_03844 7.56e-267 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
EPKFIKFJ_03845 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
EPKFIKFJ_03846 4.46e-94 ywiB - - S - - - protein conserved in bacteria
EPKFIKFJ_03848 1.55e-248 ywhL - - CO - - - amine dehydrogenase activity
EPKFIKFJ_03849 3.16e-102 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
EPKFIKFJ_03851 2.87e-213 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EPKFIKFJ_03852 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EPKFIKFJ_03853 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
EPKFIKFJ_03854 1.96e-93 - - - - - - - -
EPKFIKFJ_03855 2.07e-116 ywhD - - S - - - YwhD family
EPKFIKFJ_03856 1.29e-151 ywhC - - S - - - Peptidase family M50
EPKFIKFJ_03857 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
EPKFIKFJ_03858 3.29e-90 ywhA - - K - - - Transcriptional regulator
EPKFIKFJ_03859 4.79e-307 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
EPKFIKFJ_03860 1.37e-113 ywgA - - - ko:K09388 - ko00000 -
EPKFIKFJ_03861 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
EPKFIKFJ_03862 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
EPKFIKFJ_03863 3.27e-136 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
EPKFIKFJ_03864 4.41e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
EPKFIKFJ_03865 2.51e-109 - - - S - - - membrane
EPKFIKFJ_03866 1.93e-194 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_03867 2.13e-208 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
EPKFIKFJ_03870 4.4e-208 - - - - - - - -
EPKFIKFJ_03872 8.05e-198 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
EPKFIKFJ_03873 1.33e-199 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
EPKFIKFJ_03874 9.29e-207 - - - S - - - Conserved hypothetical protein 698
EPKFIKFJ_03875 2.27e-222 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
EPKFIKFJ_03876 6.64e-185 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
EPKFIKFJ_03877 2.37e-20 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
EPKFIKFJ_03879 6.08e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
EPKFIKFJ_03880 5.35e-289 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
EPKFIKFJ_03881 2.33e-264 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
EPKFIKFJ_03882 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
EPKFIKFJ_03883 2.21e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_03884 1.63e-174 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
EPKFIKFJ_03885 1.16e-107 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
EPKFIKFJ_03886 8.02e-277 ywfA - - EGP - - - -transporter
EPKFIKFJ_03887 4.86e-249 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
EPKFIKFJ_03888 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKFIKFJ_03889 0.0 rocB - - E - - - arginine degradation protein
EPKFIKFJ_03890 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
EPKFIKFJ_03891 8.64e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
EPKFIKFJ_03892 4.02e-80 - - - - - - - -
EPKFIKFJ_03893 2.6e-109 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
EPKFIKFJ_03894 3.3e-199 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPKFIKFJ_03895 5.41e-226 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPKFIKFJ_03896 2.9e-170 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPKFIKFJ_03897 3.01e-212 spsG - - M - - - Spore Coat
EPKFIKFJ_03898 5.52e-160 spsF - - M ko:K07257 - ko00000 Spore Coat
EPKFIKFJ_03899 2.97e-266 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
EPKFIKFJ_03900 6.34e-195 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
EPKFIKFJ_03901 2.58e-275 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
EPKFIKFJ_03902 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
EPKFIKFJ_03903 4.13e-180 spsA - - M - - - Spore Coat
EPKFIKFJ_03904 1.29e-83 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
EPKFIKFJ_03905 4.39e-76 ywdK - - S - - - small membrane protein
EPKFIKFJ_03906 3.47e-287 ywdJ - - F - - - Xanthine uracil
EPKFIKFJ_03907 2.73e-56 ywdI - - S - - - Family of unknown function (DUF5327)
EPKFIKFJ_03908 2.42e-169 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPKFIKFJ_03909 1.44e-186 ywdF - - S - - - Glycosyltransferase like family 2
EPKFIKFJ_03911 2.79e-185 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
EPKFIKFJ_03912 6.09e-27 ywdA - - - - - - -
EPKFIKFJ_03913 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
EPKFIKFJ_03914 9.04e-317 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_03915 1.29e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EPKFIKFJ_03917 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKFIKFJ_03918 3.03e-232 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EPKFIKFJ_03919 1.26e-150 - - - K - - - WYL domain
EPKFIKFJ_03920 4.96e-161 ucpA - - IQ - - - Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
EPKFIKFJ_03921 4.61e-56 - - - S - - - Ketosteroid isomerase-related protein
EPKFIKFJ_03922 1.36e-39 - - - S - - - PFAM Stress responsive alpha-beta barrel
EPKFIKFJ_03923 1.1e-176 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
EPKFIKFJ_03924 1.84e-262 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
EPKFIKFJ_03925 1.68e-87 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
EPKFIKFJ_03926 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
EPKFIKFJ_03927 1.08e-80 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EPKFIKFJ_03928 2.84e-143 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
EPKFIKFJ_03929 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EPKFIKFJ_03930 3.01e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
EPKFIKFJ_03931 5.74e-48 ydaS - - S - - - membrane
EPKFIKFJ_03932 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
EPKFIKFJ_03933 1.52e-265 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EPKFIKFJ_03934 7.8e-78 gtcA - - S - - - GtrA-like protein
EPKFIKFJ_03935 1.72e-125 - - - K - - - Bacterial regulatory proteins, tetR family
EPKFIKFJ_03937 2.7e-161 - - - H - - - Methionine biosynthesis protein MetW
EPKFIKFJ_03938 4.83e-154 - - - S - - - Streptomycin biosynthesis protein StrF
EPKFIKFJ_03939 5.52e-139 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
EPKFIKFJ_03940 9.8e-297 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
EPKFIKFJ_03941 5.83e-191 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
EPKFIKFJ_03942 2.41e-246 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
EPKFIKFJ_03943 2.72e-139 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EPKFIKFJ_03944 9.98e-164 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPKFIKFJ_03945 2.29e-200 ywbI - - K - - - Transcriptional regulator
EPKFIKFJ_03946 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
EPKFIKFJ_03947 6.2e-142 ywbG - - M - - - effector of murein hydrolase
EPKFIKFJ_03948 1.52e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
EPKFIKFJ_03949 2.16e-164 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
EPKFIKFJ_03950 1.97e-200 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
EPKFIKFJ_03951 4.69e-281 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
EPKFIKFJ_03952 1.24e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
EPKFIKFJ_03953 8.3e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPKFIKFJ_03954 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
EPKFIKFJ_03955 1.66e-204 gspA - - M - - - General stress
EPKFIKFJ_03957 2.16e-150 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
EPKFIKFJ_03958 7.25e-213 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
EPKFIKFJ_03959 3.51e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
EPKFIKFJ_03960 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_03961 2.45e-289 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
EPKFIKFJ_03962 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPKFIKFJ_03963 3.02e-244 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EPKFIKFJ_03964 1.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
EPKFIKFJ_03965 2.82e-315 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
EPKFIKFJ_03966 1.89e-64 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_03967 1.19e-312 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPKFIKFJ_03968 3.67e-65 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
EPKFIKFJ_03969 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
EPKFIKFJ_03970 4.07e-139 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
EPKFIKFJ_03971 5.23e-217 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_03972 9.33e-229 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPKFIKFJ_03973 8.85e-212 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EPKFIKFJ_03974 1.06e-66 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
EPKFIKFJ_03975 1.16e-286 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EPKFIKFJ_03976 1.35e-58 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_03977 1.26e-62 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_03978 1.84e-298 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPKFIKFJ_03979 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKFIKFJ_03980 7.52e-206 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
EPKFIKFJ_03981 1.05e-227 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
EPKFIKFJ_03982 3.3e-261 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
EPKFIKFJ_03983 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EPKFIKFJ_03984 1.26e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
EPKFIKFJ_03985 2.06e-313 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
EPKFIKFJ_03986 7.18e-140 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPKFIKFJ_03987 6.72e-37 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPKFIKFJ_03988 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
EPKFIKFJ_03989 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
EPKFIKFJ_03990 5.08e-238 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
EPKFIKFJ_03991 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
EPKFIKFJ_03992 1.02e-283 cimH - - C - - - COG3493 Na citrate symporter
EPKFIKFJ_03993 2.39e-191 yxkH - - G - - - Polysaccharide deacetylase
EPKFIKFJ_03994 3.56e-259 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
EPKFIKFJ_03995 1.49e-198 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
EPKFIKFJ_03996 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
EPKFIKFJ_03998 5.75e-115 yxkC - - S - - - Domain of unknown function (DUF4352)
EPKFIKFJ_03999 7.02e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
EPKFIKFJ_04000 5.24e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
EPKFIKFJ_04003 3.81e-105 yxjI - - S - - - LURP-one-related
EPKFIKFJ_04004 8.25e-271 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
EPKFIKFJ_04005 2.83e-185 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
EPKFIKFJ_04006 2.49e-262 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPKFIKFJ_04007 1.64e-113 - - - T - - - Domain of unknown function (DUF4163)
EPKFIKFJ_04008 3.23e-60 yxiS - - - - - - -
EPKFIKFJ_04009 3.04e-221 - - - L - - - DNA synthesis involved in DNA repair
EPKFIKFJ_04010 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
EPKFIKFJ_04011 1.57e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
EPKFIKFJ_04012 9.73e-176 bglS - - M - - - licheninase activity
EPKFIKFJ_04013 2.11e-183 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
EPKFIKFJ_04014 7.88e-277 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
EPKFIKFJ_04015 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
EPKFIKFJ_04017 9.75e-27 - - - - - - - -
EPKFIKFJ_04019 2.79e-140 - - - - - - - -
EPKFIKFJ_04020 7.34e-62 - - - - - - - -
EPKFIKFJ_04021 1.92e-42 yxiG - - - - - - -
EPKFIKFJ_04022 9.79e-75 yxxG - - - - - - -
EPKFIKFJ_04024 4.8e-251 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
EPKFIKFJ_04025 7.42e-202 yxxF - - EG - - - EamA-like transporter family
EPKFIKFJ_04026 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
EPKFIKFJ_04027 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
EPKFIKFJ_04028 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
EPKFIKFJ_04029 1.51e-61 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EPKFIKFJ_04030 8.04e-176 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
EPKFIKFJ_04031 3.55e-204 - - - L - - - Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
EPKFIKFJ_04032 0.0 - - - L - - - Z1 domain
EPKFIKFJ_04033 7.49e-103 - - - S - - - Putative PD-(D/E)XK family member, (DUF4420)
EPKFIKFJ_04034 2.49e-244 - - - S - - - AIPR protein
EPKFIKFJ_04035 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
EPKFIKFJ_04036 4.06e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
EPKFIKFJ_04037 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
EPKFIKFJ_04038 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EPKFIKFJ_04039 7.66e-291 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
EPKFIKFJ_04040 6.73e-216 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
EPKFIKFJ_04041 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKFIKFJ_04042 2.59e-295 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
EPKFIKFJ_04043 2.33e-264 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EPKFIKFJ_04044 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EPKFIKFJ_04045 9.22e-217 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
EPKFIKFJ_04046 1.75e-188 yxeH - - S - - - hydrolases of the HAD superfamily
EPKFIKFJ_04049 9.45e-26 yxeE - - - - - - -
EPKFIKFJ_04051 9.67e-33 yxeD - - - - - - -
EPKFIKFJ_04052 4.86e-47 - - - - - - - -
EPKFIKFJ_04053 6.74e-218 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
EPKFIKFJ_04054 2.25e-72 yxeA - - S - - - Protein of unknown function (DUF1093)
EPKFIKFJ_04055 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
EPKFIKFJ_04056 7.1e-177 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
EPKFIKFJ_04057 9.27e-223 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_04058 6.33e-157 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_04059 1.61e-194 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
EPKFIKFJ_04060 6.65e-198 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
EPKFIKFJ_04061 4.92e-209 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
EPKFIKFJ_04062 2.36e-246 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
EPKFIKFJ_04063 6.5e-288 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
EPKFIKFJ_04064 1.73e-218 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
EPKFIKFJ_04065 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
EPKFIKFJ_04066 1e-224 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
EPKFIKFJ_04067 1.11e-196 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
EPKFIKFJ_04068 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
EPKFIKFJ_04069 1.75e-174 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
EPKFIKFJ_04070 1.72e-215 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
EPKFIKFJ_04071 2.13e-311 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPKFIKFJ_04072 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
EPKFIKFJ_04073 1.56e-188 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
EPKFIKFJ_04074 2.06e-129 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EPKFIKFJ_04075 3.16e-243 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_04076 1.04e-247 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
EPKFIKFJ_04077 1.53e-265 yxbF - - K - - - Bacterial regulatory proteins, tetR family
EPKFIKFJ_04078 2.4e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
EPKFIKFJ_04079 2.12e-185 yxaL - - S - - - PQQ-like domain
EPKFIKFJ_04080 5.81e-75 - - - S - - - Family of unknown function (DUF5391)
EPKFIKFJ_04081 3.34e-65 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EPKFIKFJ_04082 1.16e-250 - - - EGP - - - Major Facilitator Superfamily
EPKFIKFJ_04083 2.58e-86 yxaI - - S - - - membrane protein domain
EPKFIKFJ_04084 6.29e-152 - - - E - - - Ring-cleavage extradiol dioxygenase
EPKFIKFJ_04085 9.33e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
EPKFIKFJ_04086 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
EPKFIKFJ_04087 9.59e-234 mrjp - - G - - - Major royal jelly protein
EPKFIKFJ_04088 1.26e-301 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
EPKFIKFJ_04089 9.17e-200 - - - K - - - helix_turn_helix, Deoxyribose operon repressor
EPKFIKFJ_04090 2.97e-95 - - - K - - - Integron-associated effector binding protein
EPKFIKFJ_04091 6.31e-98 yjhE - - S - - - Phage tail protein
EPKFIKFJ_04092 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
EPKFIKFJ_04093 2.84e-123 tnpR - - L - - - resolvase
EPKFIKFJ_04094 4.04e-103 - - - - - - - -
EPKFIKFJ_04096 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
EPKFIKFJ_04097 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
EPKFIKFJ_04098 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
EPKFIKFJ_04099 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
EPKFIKFJ_04100 6.17e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
EPKFIKFJ_04101 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
EPKFIKFJ_04102 6.56e-192 - - - S - - - membrane
EPKFIKFJ_04103 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_04104 0.0 - - - I - - - PLD-like domain
EPKFIKFJ_04105 1.16e-120 - - - S - - - Protein of unknown function (DUF421)
EPKFIKFJ_04106 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
EPKFIKFJ_04107 1.13e-101 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
EPKFIKFJ_04108 1.16e-182 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
EPKFIKFJ_04109 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
EPKFIKFJ_04110 8.88e-106 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
EPKFIKFJ_04111 7.21e-200 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EPKFIKFJ_04112 3.9e-208 - - - S - - - Fusaric acid resistance protein-like
EPKFIKFJ_04113 6.58e-27 - - - - - - - -
EPKFIKFJ_04114 0.0 - - - L - - - AAA domain
EPKFIKFJ_04115 0.0 - - - L - - - AAA ATPase domain
EPKFIKFJ_04116 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPKFIKFJ_04120 5.96e-264 yycP - - - - - - -
EPKFIKFJ_04121 1.54e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
EPKFIKFJ_04122 3.13e-226 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
EPKFIKFJ_04123 2.13e-106 yycN - - K - - - Acetyltransferase
EPKFIKFJ_04125 2.05e-256 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
EPKFIKFJ_04126 7.27e-210 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
EPKFIKFJ_04127 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
EPKFIKFJ_04128 1.75e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
EPKFIKFJ_04129 1.26e-85 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
EPKFIKFJ_04130 3.82e-57 sdpR - - K - - - transcriptional
EPKFIKFJ_04131 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
EPKFIKFJ_04132 8.24e-255 - - - S - - - Major Facilitator Superfamily
EPKFIKFJ_04133 5.41e-310 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
EPKFIKFJ_04134 3.35e-119 - - - K ko:K02483 - ko00000,ko02022 PFAM response regulator receiver
EPKFIKFJ_04135 3.32e-63 - - - S - - - Peptidase propeptide and YPEB domain
EPKFIKFJ_04136 1.37e-270 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EPKFIKFJ_04137 4.01e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
EPKFIKFJ_04138 6.34e-191 yycI - - S - - - protein conserved in bacteria
EPKFIKFJ_04139 0.0 yycH - - S - - - protein conserved in bacteria
EPKFIKFJ_04140 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
EPKFIKFJ_04141 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EPKFIKFJ_04146 4.45e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPKFIKFJ_04147 1.06e-92 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKFIKFJ_04148 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
EPKFIKFJ_04149 5.03e-35 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
EPKFIKFJ_04151 1.21e-23 yycC - - K - - - YycC-like protein
EPKFIKFJ_04152 3.86e-271 - - - M - - - Glycosyltransferase Family 4
EPKFIKFJ_04153 4.55e-243 - - - S - - - Ecdysteroid kinase
EPKFIKFJ_04154 2.87e-291 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
EPKFIKFJ_04155 3.93e-279 - - - M - - - Glycosyltransferase Family 4
EPKFIKFJ_04156 1.44e-150 - - - S - - - GlcNAc-PI de-N-acetylase
EPKFIKFJ_04157 4.29e-103 - - - KLT - - - COG0515 Serine threonine protein kinase
EPKFIKFJ_04158 2.25e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
EPKFIKFJ_04159 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
EPKFIKFJ_04160 8.64e-189 yybS - - S - - - membrane
EPKFIKFJ_04161 3.93e-104 cotF - - M ko:K06329 - ko00000 Spore coat protein
EPKFIKFJ_04162 1.79e-84 yybR - - K - - - Transcriptional regulator
EPKFIKFJ_04163 4.01e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
EPKFIKFJ_04164 4.42e-192 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EPKFIKFJ_04165 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
EPKFIKFJ_04166 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
EPKFIKFJ_04167 7.61e-142 - - - K - - - FCD domain
EPKFIKFJ_04168 3.74e-115 - - - S - - - PFAM DinB family protein
EPKFIKFJ_04169 1.96e-184 - - - G - - - Major Facilitator Superfamily
EPKFIKFJ_04170 3.76e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
EPKFIKFJ_04171 1.56e-144 ydgI - - C - - - nitroreductase
EPKFIKFJ_04172 2.55e-85 - - - K - - - Winged helix DNA-binding domain
EPKFIKFJ_04173 7.02e-190 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
EPKFIKFJ_04174 7.24e-97 yybA - - K - - - transcriptional
EPKFIKFJ_04175 2.85e-92 yjcF - - S - - - Acetyltransferase (GNAT) domain
EPKFIKFJ_04176 5e-27 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
EPKFIKFJ_04177 2.47e-129 - - - S - - - Alpha/beta hydrolase family
EPKFIKFJ_04178 1.63e-31 - - - L - - - Recombinase
EPKFIKFJ_04179 5.5e-158 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKFIKFJ_04182 1.45e-55 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
EPKFIKFJ_04183 3.82e-73 yddI - - - - - - -
EPKFIKFJ_04184 1.03e-200 yddH - - M - - - Lysozyme-like
EPKFIKFJ_04185 1.68e-258 yddG - - S - - - maturation of SSU-rRNA
EPKFIKFJ_04186 9.22e-47 - - - S - - - Domain of unknown function (DUF1874)
EPKFIKFJ_04187 0.0 yddE - - S - - - AAA-like domain
EPKFIKFJ_04188 3.06e-96 yddD - - S - - - TcpE family
EPKFIKFJ_04189 2.72e-33 yddC - - - - - - -
EPKFIKFJ_04190 1.21e-163 yddB - - S - - - Conjugative transposon protein TcpC
EPKFIKFJ_04195 8.93e-23 - - - S - - - Domain of Unknown Function with PDB structure (DUF3850)
EPKFIKFJ_04196 4.41e-216 nicK - - L ko:K07467 - ko00000 Replication initiation factor
EPKFIKFJ_04197 4.49e-155 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
EPKFIKFJ_04198 9.6e-272 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
EPKFIKFJ_04200 5.01e-44 - - - S - - - Bacterial protein of unknown function (DUF961)
EPKFIKFJ_04202 1.16e-20 - - - - - - - -
EPKFIKFJ_04203 7.41e-54 - - - K - - - Transcriptional
EPKFIKFJ_04204 1.26e-57 - - - E - - - IrrE N-terminal-like domain
EPKFIKFJ_04206 4.45e-92 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
EPKFIKFJ_04207 6.5e-27 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EPKFIKFJ_04208 1.41e-158 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EPKFIKFJ_04209 7.39e-264 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
EPKFIKFJ_04210 4.75e-193 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
EPKFIKFJ_04211 2.8e-311 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
EPKFIKFJ_04212 9.47e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPKFIKFJ_04213 1.16e-117 ccpB - - K - - - Transcriptional regulator
EPKFIKFJ_04214 6.26e-78 ccpB - - K - - - Transcriptional regulator
EPKFIKFJ_04215 2.49e-179 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
EPKFIKFJ_04216 6.58e-112 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPKFIKFJ_04217 3.59e-123 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
EPKFIKFJ_04218 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPKFIKFJ_04219 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EPKFIKFJ_04220 3.39e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
EPKFIKFJ_04221 6.32e-253 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPKFIKFJ_04222 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPKFIKFJ_04223 1.82e-45 yyzM - - S - - - protein conserved in bacteria
EPKFIKFJ_04224 3.84e-215 yyaD - - S - - - Membrane
EPKFIKFJ_04225 2.63e-74 yhhY - - K - - - FR47-like protein
EPKFIKFJ_04226 1.3e-139 yyaC - - S - - - Sporulation protein YyaC
EPKFIKFJ_04227 2.76e-187 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
EPKFIKFJ_04228 2.49e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
EPKFIKFJ_04229 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
EPKFIKFJ_04230 2.56e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
EPKFIKFJ_04231 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EPKFIKFJ_04232 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPKFIKFJ_04233 7.08e-137 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
EPKFIKFJ_04234 6.08e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPKFIKFJ_04235 1.84e-67 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EPKFIKFJ_04236 3.25e-79 - - - L - - - Bacterial transcription activator, effector binding domain
EPKFIKFJ_04238 1.03e-125 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EPKFIKFJ_04239 5.13e-28 yiiD - - K ko:K06323 - ko00000 acetyltransferase
EPKFIKFJ_04240 1e-207 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
EPKFIKFJ_04241 2.84e-54 cgeC - - - ko:K06321 - ko00000 -
EPKFIKFJ_04242 5.86e-25 cgeA - - - ko:K06319 - ko00000 -
EPKFIKFJ_04243 2.04e-20 cgeA - - - ko:K06319 - ko00000 -
EPKFIKFJ_04244 6.45e-215 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
EPKFIKFJ_04245 7.88e-267 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
EPKFIKFJ_04246 4.5e-155 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
EPKFIKFJ_04247 2.47e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
EPKFIKFJ_04248 1.34e-130 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPKFIKFJ_04249 1.41e-22 ypoP - - K - - - transcriptional
EPKFIKFJ_04250 2.45e-122 ypmS - - S - - - protein conserved in bacteria
EPKFIKFJ_04251 3.62e-167 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
EPKFIKFJ_04252 2.24e-131 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
EPKFIKFJ_04253 3.66e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
EPKFIKFJ_04254 4.1e-136 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPKFIKFJ_04255 9.42e-31 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPKFIKFJ_04256 5.74e-75 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EPKFIKFJ_04257 2.17e-168 yplP - - K - - - Transcriptional regulator
EPKFIKFJ_04258 1.3e-79 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EPKFIKFJ_04259 4.37e-47 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
EPKFIKFJ_04260 6.89e-41 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
EPKFIKFJ_04261 4.89e-36 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPKFIKFJ_04262 2.23e-36 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPKFIKFJ_04263 6.46e-24 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPKFIKFJ_04264 1.57e-136 ypjP - - S - - - YpjP-like protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)