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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MHKMKOHG_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHKMKOHG_00002	2.83e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHKMKOHG_00003	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MHKMKOHG_00004	1.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHKMKOHG_00005	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
MHKMKOHG_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHKMKOHG_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHKMKOHG_00008	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_00009	1.41e-225	yaaC	-	-	S	-	-	-	YaaC-like Protein
MHKMKOHG_00010	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHKMKOHG_00011	2.81e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MHKMKOHG_00012	7.47e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHKMKOHG_00013	1.93e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHKMKOHG_00014	8.78e-283	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHKMKOHG_00015	1.36e-250	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MHKMKOHG_00017	6.92e-155	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MHKMKOHG_00018	3.32e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MHKMKOHG_00019	3.6e-271	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MHKMKOHG_00020	9.33e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MHKMKOHG_00021	2.78e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHKMKOHG_00022	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHKMKOHG_00023	6.9e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHKMKOHG_00024	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHKMKOHG_00025	7.67e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MHKMKOHG_00026	1.78e-47	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
MHKMKOHG_00027	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_00028	1.5e-40	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
MHKMKOHG_00029	3.02e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHKMKOHG_00030	3.13e-226	yaaN	-	-	P	-	-	-	Belongs to the TelA family
MHKMKOHG_00031	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MHKMKOHG_00032	4.13e-140	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHKMKOHG_00033	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_00034	7.03e-93	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MHKMKOHG_00035	8.67e-230	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MHKMKOHG_00036	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MHKMKOHG_00037	2.53e-55	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MHKMKOHG_00038	1.56e-175	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MHKMKOHG_00039	1.35e-61	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MHKMKOHG_00040	2.81e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHKMKOHG_00041	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MHKMKOHG_00042	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHKMKOHG_00043	1.44e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MHKMKOHG_00044	2.91e-287	yabE	-	-	T	-	-	-	protein conserved in bacteria
MHKMKOHG_00045	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHKMKOHG_00046	6.62e-200	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHKMKOHG_00047	1.46e-186	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MHKMKOHG_00048	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_00049	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MHKMKOHG_00050	1.84e-204	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHKMKOHG_00051	7.72e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MHKMKOHG_00052	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MHKMKOHG_00053	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MHKMKOHG_00054	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHKMKOHG_00055	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHKMKOHG_00056	1.4e-133	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHKMKOHG_00057	4.99e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHKMKOHG_00058	5.24e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MHKMKOHG_00059	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHKMKOHG_00060	2.69e-117	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MHKMKOHG_00061	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKMKOHG_00062	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MHKMKOHG_00063	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MHKMKOHG_00064	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
MHKMKOHG_00065	1.79e-129	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MHKMKOHG_00066	2.42e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MHKMKOHG_00067	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MHKMKOHG_00070	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MHKMKOHG_00071	8.92e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MHKMKOHG_00072	4.82e-229	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MHKMKOHG_00073	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHKMKOHG_00074	4.29e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MHKMKOHG_00075	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHKMKOHG_00076	6.69e-177	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHKMKOHG_00077	7.52e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHKMKOHG_00078	4.24e-193	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
MHKMKOHG_00079	1.79e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MHKMKOHG_00080	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHKMKOHG_00081	6e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MHKMKOHG_00082	2.61e-190	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MHKMKOHG_00083	1.98e-197	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHKMKOHG_00084	1.88e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHKMKOHG_00085	8.84e-113	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MHKMKOHG_00086	9.99e-39	yazB	-	-	K	-	-	-	transcriptional
MHKMKOHG_00087	8.33e-230	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHKMKOHG_00088	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MHKMKOHG_00089	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_00092	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MHKMKOHG_00093	9.99e-78	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MHKMKOHG_00094	3.84e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MHKMKOHG_00095	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MHKMKOHG_00096	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHKMKOHG_00097	3.64e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MHKMKOHG_00098	1.85e-245	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MHKMKOHG_00099	2.89e-157	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHKMKOHG_00100	1.23e-110	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHKMKOHG_00101	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHKMKOHG_00102	1.91e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MHKMKOHG_00103	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MHKMKOHG_00104	1.61e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHKMKOHG_00105	3.38e-171	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHKMKOHG_00106	1.92e-113	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MHKMKOHG_00107	4.65e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MHKMKOHG_00108	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHKMKOHG_00109	6.9e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MHKMKOHG_00110	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHKMKOHG_00111	5.01e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHKMKOHG_00112	6.68e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHKMKOHG_00113	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHKMKOHG_00114	1.46e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MHKMKOHG_00115	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHKMKOHG_00116	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHKMKOHG_00117	9.87e-45	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MHKMKOHG_00118	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHKMKOHG_00119	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHKMKOHG_00120	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHKMKOHG_00121	9.55e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHKMKOHG_00122	4.4e-221	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
MHKMKOHG_00123	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MHKMKOHG_00124	1.02e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHKMKOHG_00125	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MHKMKOHG_00126	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHKMKOHG_00127	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHKMKOHG_00128	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHKMKOHG_00129	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHKMKOHG_00130	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHKMKOHG_00131	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHKMKOHG_00132	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MHKMKOHG_00133	1.92e-51	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHKMKOHG_00134	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHKMKOHG_00135	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHKMKOHG_00136	2.58e-120	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHKMKOHG_00137	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHKMKOHG_00138	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHKMKOHG_00139	1.05e-119	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHKMKOHG_00140	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHKMKOHG_00141	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHKMKOHG_00142	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MHKMKOHG_00143	2.1e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MHKMKOHG_00144	1.82e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHKMKOHG_00145	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHKMKOHG_00146	5.46e-181	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MHKMKOHG_00147	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHKMKOHG_00148	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MHKMKOHG_00149	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHKMKOHG_00150	4.61e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHKMKOHG_00151	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHKMKOHG_00152	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MHKMKOHG_00153	6.9e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHKMKOHG_00154	1.83e-185	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHKMKOHG_00155	7.6e-176	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHKMKOHG_00156	3.42e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHKMKOHG_00157	3.79e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHKMKOHG_00158	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MHKMKOHG_00159	4.46e-179	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
MHKMKOHG_00161	2.28e-99	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MHKMKOHG_00162	4.3e-168	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MHKMKOHG_00163	1.6e-247	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHKMKOHG_00164	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
MHKMKOHG_00165	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MHKMKOHG_00166	1.14e-176	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MHKMKOHG_00167	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_00175	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_00178	2.1e-270	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MHKMKOHG_00179	4.26e-312	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHKMKOHG_00180	1.75e-227	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
MHKMKOHG_00181	1.33e-254	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MHKMKOHG_00182	9.71e-282	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MHKMKOHG_00183	7.81e-216	ybaS	-	-	S	-	-	-	Na -dependent transporter
MHKMKOHG_00184	4.7e-128	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
MHKMKOHG_00185	5.99e-224	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_00186	1.48e-224	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_00187	3.89e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MHKMKOHG_00188	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MHKMKOHG_00189	1.88e-292	ybbC	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_00190	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MHKMKOHG_00191	5.92e-298	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MHKMKOHG_00192	2.72e-299	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_00193	4.48e-206	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHKMKOHG_00194	3.4e-108	ybbJ	-	-	J	-	-	-	acetyltransferase
MHKMKOHG_00195	4.36e-98	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
MHKMKOHG_00201	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_00202	1.7e-146	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MHKMKOHG_00203	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHKMKOHG_00204	7.78e-292	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_00205	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHKMKOHG_00206	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHKMKOHG_00207	1.73e-189	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHKMKOHG_00208	1.16e-131	-	-	-	S	-	-	-	ABC-2 family transporter protein
MHKMKOHG_00209	5.62e-35	ybdN	-	-	-	-	-	-	-
MHKMKOHG_00210	2.57e-58	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_00211	1.76e-162	-	-	-	T	ko:K11630	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_00212	5.45e-234	-	-	-	T	ko:K19168	-	ko00000,ko02048	Histidine kinase
MHKMKOHG_00213	3.8e-175	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_00214	0.0	-	-	-	V	ko:K02004,ko:K11632	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MHKMKOHG_00215	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHKMKOHG_00216	6.16e-199	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
MHKMKOHG_00217	1.42e-133	yxaC	-	-	M	-	-	-	effector of murein hydrolase
MHKMKOHG_00218	3.67e-34	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
MHKMKOHG_00219	2.57e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_00220	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHKMKOHG_00221	1.52e-118	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MHKMKOHG_00222	2.94e-231	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
MHKMKOHG_00223	5.5e-128	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MHKMKOHG_00224	1.06e-205	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MHKMKOHG_00225	1.17e-242	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MHKMKOHG_00226	4.65e-230	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MHKMKOHG_00227	3.22e-33	-	-	-	-	-	-	-	-
MHKMKOHG_00228	5.2e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
MHKMKOHG_00229	2.48e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
MHKMKOHG_00230	1.04e-136	yqeB	-	-	-	-	-	-	-
MHKMKOHG_00231	6.22e-52	ybyB	-	-	-	-	-	-	-
MHKMKOHG_00232	0.0	ybeC	-	-	E	-	-	-	amino acid
MHKMKOHG_00233	3.11e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MHKMKOHG_00234	3.73e-209	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
MHKMKOHG_00235	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
MHKMKOHG_00236	2.47e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
MHKMKOHG_00237	6.44e-261	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MHKMKOHG_00239	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
MHKMKOHG_00241	1.34e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHKMKOHG_00242	3.98e-237	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MHKMKOHG_00243	2.85e-265	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHKMKOHG_00244	9.04e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHKMKOHG_00245	3.37e-110	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
MHKMKOHG_00246	4.85e-191	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MHKMKOHG_00247	4.65e-50	ybfN	-	-	-	-	-	-	-
MHKMKOHG_00248	1.78e-239	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MHKMKOHG_00249	5.27e-266	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKMKOHG_00250	1.04e-248	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MHKMKOHG_00251	8.9e-317	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHKMKOHG_00252	3.81e-226	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
MHKMKOHG_00253	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MHKMKOHG_00254	8.78e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MHKMKOHG_00255	9.19e-265	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_00256	2.43e-197	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
MHKMKOHG_00257	4.88e-160	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
MHKMKOHG_00258	3.3e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
MHKMKOHG_00259	8.64e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHKMKOHG_00260	2.72e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
MHKMKOHG_00261	8.39e-233	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MHKMKOHG_00262	3.27e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
MHKMKOHG_00263	3.92e-76	ydfQ	-	-	CO	-	-	-	Thioredoxin
MHKMKOHG_00264	4.68e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MHKMKOHG_00265	3.67e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MHKMKOHG_00266	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
MHKMKOHG_00267	5.03e-35	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHKMKOHG_00268	8.7e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHKMKOHG_00269	1.4e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHKMKOHG_00270	1.65e-248	ycbU	-	-	E	-	-	-	Selenocysteine lyase
MHKMKOHG_00271	2.09e-305	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MHKMKOHG_00272	3.35e-125	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MHKMKOHG_00273	4.81e-140	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MHKMKOHG_00274	7.31e-247	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MHKMKOHG_00275	2.62e-210	yccK	-	-	C	-	-	-	Aldo keto reductase
MHKMKOHG_00276	1.8e-207	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
MHKMKOHG_00277	3.86e-222	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_00278	9.14e-317	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_00279	1.86e-114	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MHKMKOHG_00280	3.74e-221	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
MHKMKOHG_00281	6.52e-174	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MHKMKOHG_00282	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MHKMKOHG_00283	3.69e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
MHKMKOHG_00284	9.24e-63	-	-	-	K	-	-	-	Virulence activator alpha C-term
MHKMKOHG_00285	1.35e-212	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MHKMKOHG_00286	1.15e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MHKMKOHG_00287	1.38e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MHKMKOHG_00288	1.06e-231	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKMKOHG_00289	4.35e-31	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MHKMKOHG_00290	1.8e-97	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
MHKMKOHG_00291	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MHKMKOHG_00292	1.94e-135	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
MHKMKOHG_00293	4.28e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
MHKMKOHG_00294	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
MHKMKOHG_00295	1.36e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
MHKMKOHG_00296	3.23e-270	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
MHKMKOHG_00298	2.12e-291	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MHKMKOHG_00299	7.02e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MHKMKOHG_00300	4.54e-207	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MHKMKOHG_00301	3.87e-262	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
MHKMKOHG_00302	4.05e-287	ycgA	-	-	S	-	-	-	Membrane
MHKMKOHG_00303	1.04e-53	ycgB	-	-	-	-	-	-	-
MHKMKOHG_00304	2.85e-15	-	-	-	S	-	-	-	RDD family
MHKMKOHG_00305	8.99e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MHKMKOHG_00306	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MHKMKOHG_00307	1.39e-34	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_00308	2e-36	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_00309	3.18e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MHKMKOHG_00310	4.7e-189	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
MHKMKOHG_00311	3.93e-306	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHKMKOHG_00312	6.25e-144	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
MHKMKOHG_00313	1.44e-188	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHKMKOHG_00314	4.54e-169	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
MHKMKOHG_00315	1.66e-288	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_00316	2.04e-134	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHKMKOHG_00317	1.83e-230	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MHKMKOHG_00318	2.89e-178	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
MHKMKOHG_00319	2.64e-214	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MHKMKOHG_00320	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHKMKOHG_00321	1.05e-309	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHKMKOHG_00322	1.86e-286	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
MHKMKOHG_00323	1.07e-238	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MHKMKOHG_00324	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MHKMKOHG_00325	2.34e-72	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MHKMKOHG_00326	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MHKMKOHG_00327	1.8e-50	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MHKMKOHG_00328	4.18e-282	yciC	-	-	S	-	-	-	GTPases (G3E family)
MHKMKOHG_00329	6.16e-277	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHKMKOHG_00330	3.65e-94	yckC	-	-	S	-	-	-	membrane
MHKMKOHG_00331	7.52e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
MHKMKOHG_00332	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHKMKOHG_00333	7.34e-86	nin	-	-	S	-	-	-	Competence protein J (ComJ)
MHKMKOHG_00334	2.67e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MHKMKOHG_00335	1.22e-121	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MHKMKOHG_00336	2.27e-132	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MHKMKOHG_00337	2.89e-84	hxlR	-	-	K	-	-	-	transcriptional
MHKMKOHG_00338	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_00339	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_00340	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_00341	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
MHKMKOHG_00342	1.34e-174	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
MHKMKOHG_00343	2.48e-315	-	-	-	E	-	-	-	Aminotransferase class I and II
MHKMKOHG_00344	4.14e-155	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
MHKMKOHG_00345	1.59e-137	yczE	-	-	S	ko:K07149	-	ko00000	membrane
MHKMKOHG_00346	9.29e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHKMKOHG_00347	5.85e-152	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MHKMKOHG_00348	1.1e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MHKMKOHG_00349	2.49e-198	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
MHKMKOHG_00350	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MHKMKOHG_00351	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MHKMKOHG_00352	6.46e-49	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
MHKMKOHG_00353	8.93e-96	yclD	-	-	-	-	-	-	-
MHKMKOHG_00354	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
MHKMKOHG_00355	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
MHKMKOHG_00357	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MHKMKOHG_00358	1.87e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
MHKMKOHG_00359	4.89e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
MHKMKOHG_00360	8.5e-316	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKMKOHG_00361	2.47e-117	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHKMKOHG_00362	2.03e-179	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MHKMKOHG_00363	8.59e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MHKMKOHG_00364	2.66e-168	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_00365	7.36e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MHKMKOHG_00366	7e-303	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
MHKMKOHG_00367	1.23e-153	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MHKMKOHG_00368	2.33e-282	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
MHKMKOHG_00369	8.72e-163	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_00370	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MHKMKOHG_00371	7.01e-96	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MHKMKOHG_00374	4.17e-314	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MHKMKOHG_00375	1.06e-208	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_00376	1.4e-212	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_00377	6.31e-173	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_00378	2.89e-221	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MHKMKOHG_00379	1.97e-311	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MHKMKOHG_00380	4.78e-192	ycnC	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00381	2.68e-172	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
MHKMKOHG_00382	2.79e-59	ycnE	-	-	S	-	-	-	Monooxygenase
MHKMKOHG_00383	1.08e-67	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MHKMKOHG_00384	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKMKOHG_00385	2.59e-279	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHKMKOHG_00386	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKMKOHG_00387	3.93e-189	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
MHKMKOHG_00388	7.4e-181	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_00389	1.33e-127	ycnI	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_00390	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
MHKMKOHG_00391	4.78e-135	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MHKMKOHG_00392	6.5e-71	-	-	-	-	-	-	-	-
MHKMKOHG_00393	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MHKMKOHG_00394	1.96e-93	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MHKMKOHG_00395	1.38e-255	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MHKMKOHG_00396	4.09e-78	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
MHKMKOHG_00398	2.59e-175	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MHKMKOHG_00399	1e-170	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MHKMKOHG_00400	3.46e-267	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MHKMKOHG_00401	1.68e-183	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
MHKMKOHG_00402	1.18e-168	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MHKMKOHG_00403	8.55e-225	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MHKMKOHG_00404	3.33e-162	kipR	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00405	4.64e-142	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MHKMKOHG_00407	3.88e-71	yczJ	-	-	S	-	-	-	biosynthesis
MHKMKOHG_00408	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MHKMKOHG_00409	7.28e-212	ycsN	-	-	S	-	-	-	Oxidoreductase
MHKMKOHG_00410	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MHKMKOHG_00411	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
MHKMKOHG_00412	5.81e-200	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_00413	7.59e-123	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MHKMKOHG_00414	3.16e-137	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHKMKOHG_00415	4.32e-100	ydaG	-	-	S	-	-	-	general stress protein
MHKMKOHG_00416	9.89e-174	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MHKMKOHG_00417	1.09e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MHKMKOHG_00418	3.25e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MHKMKOHG_00419	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHKMKOHG_00420	1.34e-240	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
MHKMKOHG_00421	2.35e-183	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
MHKMKOHG_00422	0.0	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
MHKMKOHG_00423	4.35e-301	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MHKMKOHG_00424	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
MHKMKOHG_00425	0.0	ydaO	-	-	E	-	-	-	amino acid
MHKMKOHG_00426	1.58e-286	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MHKMKOHG_00427	2.4e-85	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MHKMKOHG_00428	5.03e-80	-	-	-	K	-	-	-	acetyltransferase
MHKMKOHG_00429	7.58e-111	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHKMKOHG_00430	1.3e-84	-	-	-	-	-	-	-	-
MHKMKOHG_00431	1.07e-263	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MHKMKOHG_00434	2.14e-53	-	-	-	-	-	-	-	-
MHKMKOHG_00435	1.03e-285	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MHKMKOHG_00437	1.95e-45	ydaT	-	-	-	-	-	-	-
MHKMKOHG_00438	1.12e-95	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
MHKMKOHG_00439	2.76e-69	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
MHKMKOHG_00440	6.18e-172	ydbA	-	-	P	-	-	-	EcsC protein family
MHKMKOHG_00441	5.1e-09	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MHKMKOHG_00442	1.04e-75	ydbB	-	-	G	-	-	-	Cupin domain
MHKMKOHG_00443	4.64e-76	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
MHKMKOHG_00444	2.61e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
MHKMKOHG_00445	7.93e-248	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MHKMKOHG_00446	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MHKMKOHG_00447	1.87e-146	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MHKMKOHG_00448	1.07e-284	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKMKOHG_00449	1.85e-225	ydbI	-	-	S	-	-	-	AI-2E family transporter
MHKMKOHG_00450	1.79e-216	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_00451	2.73e-164	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHKMKOHG_00452	1.32e-69	ydbL	-	-	-	-	-	-	-
MHKMKOHG_00453	1.16e-257	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MHKMKOHG_00454	2.36e-17	-	-	-	S	-	-	-	Fur-regulated basic protein B
MHKMKOHG_00455	6.11e-15	-	-	-	S	-	-	-	Fur-regulated basic protein A
MHKMKOHG_00456	9.92e-161	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHKMKOHG_00457	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
MHKMKOHG_00458	2.07e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MHKMKOHG_00459	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHKMKOHG_00460	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHKMKOHG_00461	1.11e-91	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MHKMKOHG_00462	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MHKMKOHG_00463	3.32e-135	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MHKMKOHG_00464	9.63e-70	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHKMKOHG_00465	1.18e-230	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MHKMKOHG_00466	7.09e-273	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHKMKOHG_00467	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MHKMKOHG_00468	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MHKMKOHG_00469	9.89e-176	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MHKMKOHG_00470	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MHKMKOHG_00471	9.55e-44	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHKMKOHG_00472	1.55e-22	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MHKMKOHG_00473	4.02e-238	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MHKMKOHG_00474	3.28e-69	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MHKMKOHG_00475	5.84e-110	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MHKMKOHG_00476	2.67e-179	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKMKOHG_00477	1.07e-136	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MHKMKOHG_00478	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MHKMKOHG_00479	1.78e-21	-	-	-	-	-	-	-	-
MHKMKOHG_00480	5.5e-103	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MHKMKOHG_00488	1.06e-176	-	-	-	I	ko:K01066	-	ko00000,ko01000	esterase
MHKMKOHG_00489	3.54e-62	ohrB	-	-	O	-	-	-	OsmC-like protein
MHKMKOHG_00490	7.77e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00493	1.21e-215	ybfA	-	-	K	-	-	-	FR47-like protein
MHKMKOHG_00494	1.64e-287	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_00495	1.77e-239	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MHKMKOHG_00496	1.13e-26	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
MHKMKOHG_00498	2.05e-100	-	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00499	7.03e-123	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHKMKOHG_00500	3.05e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MHKMKOHG_00501	1.9e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3888)
MHKMKOHG_00502	0.0	-	-	-	M	-	-	-	Domain of unknown function DUF11
MHKMKOHG_00503	5.62e-97	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MHKMKOHG_00504	3.21e-144	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MHKMKOHG_00505	1.22e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MHKMKOHG_00506	6.49e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MHKMKOHG_00507	6.94e-301	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKMKOHG_00508	4.16e-240	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
MHKMKOHG_00509	8.2e-219	-	-	-	S	-	-	-	Patatin-like phospholipase
MHKMKOHG_00511	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
MHKMKOHG_00512	5.25e-90	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKMKOHG_00513	7.27e-197	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MHKMKOHG_00514	1.34e-200	-	-	-	S	-	-	-	SNARE associated Golgi protein
MHKMKOHG_00515	1.4e-92	yrkC	-	-	G	-	-	-	Cupin domain
MHKMKOHG_00516	3.15e-109	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
MHKMKOHG_00517	6.02e-187	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MHKMKOHG_00519	2.65e-133	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MHKMKOHG_00520	1.07e-79	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MHKMKOHG_00521	7.14e-63	ydeH	-	-	-	-	-	-	-
MHKMKOHG_00522	1e-203	-	-	-	S	-	-	-	Sodium Bile acid symporter family
MHKMKOHG_00523	1.32e-250	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
MHKMKOHG_00524	1.3e-80	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MHKMKOHG_00525	1.28e-277	nhaC_1	-	-	C	-	-	-	antiporter
MHKMKOHG_00526	3.85e-313	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MHKMKOHG_00527	1.28e-131	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_00529	3.67e-235	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MHKMKOHG_00530	4.29e-129	ydeS	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00531	1.42e-190	ydeK	-	-	EG	-	-	-	-transporter
MHKMKOHG_00532	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKMKOHG_00533	1.16e-62	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
MHKMKOHG_00534	1.45e-34	yraE	-	-	-	ko:K06440	-	ko00000	-
MHKMKOHG_00535	3.98e-278	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MHKMKOHG_00536	4.76e-84	yraF	-	-	M	-	-	-	Spore coat protein
MHKMKOHG_00537	4.73e-47	yraG	-	-	-	ko:K06440	-	ko00000	-
MHKMKOHG_00538	6.07e-165	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MHKMKOHG_00539	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MHKMKOHG_00540	3.55e-116	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHKMKOHG_00541	1.43e-190	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHKMKOHG_00542	3.1e-249	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MHKMKOHG_00543	6.89e-262	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MHKMKOHG_00544	9.87e-282	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHKMKOHG_00545	8.75e-198	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHKMKOHG_00546	1.05e-156	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHKMKOHG_00547	5.49e-102	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
MHKMKOHG_00548	2.96e-177	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHKMKOHG_00549	1.84e-184	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHKMKOHG_00550	2.71e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MHKMKOHG_00551	3.02e-134	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
MHKMKOHG_00552	5.93e-212	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Isocitrate/isopropylmalate dehydrogenase
MHKMKOHG_00553	1.3e-144	ydhC	-	-	K	-	-	-	FCD
MHKMKOHG_00554	1.44e-276	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHKMKOHG_00556	8.03e-311	pbpE	-	-	V	-	-	-	Beta-lactamase
MHKMKOHG_00558	6.82e-125	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MHKMKOHG_00559	1.76e-244	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MHKMKOHG_00560	2.21e-166	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
MHKMKOHG_00561	3.9e-146	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MHKMKOHG_00562	1.15e-265	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MHKMKOHG_00563	2.88e-63	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
MHKMKOHG_00564	4.14e-63	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MHKMKOHG_00565	5.78e-133	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00566	0.0	ybeC	-	-	E	-	-	-	amino acid
MHKMKOHG_00567	1.65e-209	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MHKMKOHG_00568	7.76e-108	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MHKMKOHG_00569	2.29e-227	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
MHKMKOHG_00570	2.41e-313	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHKMKOHG_00573	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_00576	1.21e-218	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MHKMKOHG_00577	5.87e-109	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MHKMKOHG_00578	2.69e-158	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MHKMKOHG_00579	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHKMKOHG_00580	3.45e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHKMKOHG_00581	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MHKMKOHG_00582	5.96e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MHKMKOHG_00583	1.51e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHKMKOHG_00584	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MHKMKOHG_00585	7.81e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MHKMKOHG_00586	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
MHKMKOHG_00587	9.24e-162	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MHKMKOHG_00588	1.24e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHKMKOHG_00589	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHKMKOHG_00590	8.33e-44	-	-	-	L	-	-	-	Arm DNA-binding domain
MHKMKOHG_00591	1.84e-35	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MHKMKOHG_00592	2.86e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MHKMKOHG_00593	4.13e-19	-	-	-	K	-	-	-	sequence-specific DNA binding
MHKMKOHG_00594	7.68e-13	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHKMKOHG_00595	5.66e-32	-	-	-	-	-	-	-	-
MHKMKOHG_00596	3.4e-51	-	-	-	S	-	-	-	DNA binding
MHKMKOHG_00597	3.27e-110	-	-	-	-	-	-	-	-
MHKMKOHG_00602	2.44e-189	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
MHKMKOHG_00603	3.3e-167	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MHKMKOHG_00604	2.26e-37	yqaL	-	-	L	-	-	-	DnaD domain protein
MHKMKOHG_00605	3.44e-101	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
MHKMKOHG_00609	3.16e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
MHKMKOHG_00611	1.16e-23	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
MHKMKOHG_00616	1.23e-72	-	-	-	-	-	-	-	-
MHKMKOHG_00618	1.04e-09	-	-	-	S	-	-	-	YopX protein
MHKMKOHG_00625	5.99e-59	-	-	-	-	-	-	-	-
MHKMKOHG_00628	1.19e-87	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MHKMKOHG_00630	1.74e-17	-	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00632	8.26e-61	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
MHKMKOHG_00633	2.61e-246	-	-	-	S	-	-	-	Phage terminase large subunit
MHKMKOHG_00634	1.62e-149	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MHKMKOHG_00635	4.69e-115	-	-	-	S	-	-	-	Phage Mu protein F like protein
MHKMKOHG_00636	5.41e-56	-	-	-	S	-	-	-	Phage minor structural protein GP20
MHKMKOHG_00637	9.15e-60	-	-	-	-	-	-	-	-
MHKMKOHG_00639	2.05e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MHKMKOHG_00640	4.25e-37	-	-	-	S	-	-	-	Phage head-tail joining protein
MHKMKOHG_00641	9.08e-50	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MHKMKOHG_00642	2.82e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
MHKMKOHG_00643	3.7e-43	-	-	-	S	-	-	-	Phage tail tube protein
MHKMKOHG_00645	9.43e-171	-	-	-	-	-	-	-	-
MHKMKOHG_00647	4.45e-282	-	-	-	S	-	-	-	peptidoglycan catabolic process
MHKMKOHG_00652	1.19e-40	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MHKMKOHG_00653	2.95e-37	xhlB	-	-	S	-	-	-	SPP1 phage holin
MHKMKOHG_00654	7.16e-83	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	Ami_2
MHKMKOHG_00655	5.89e-23	-	-	-	-	-	-	-	-
MHKMKOHG_00656	2.66e-51	-	-	-	-	-	-	-	-
MHKMKOHG_00657	1.43e-66	-	-	-	L	-	-	-	transposase activity
MHKMKOHG_00658	2.55e-160	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
MHKMKOHG_00659	0.0	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
MHKMKOHG_00660	1.53e-128	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
MHKMKOHG_00662	2.21e-81	-	-	-	-	-	-	-	-
MHKMKOHG_00663	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
MHKMKOHG_00664	2.29e-253	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MHKMKOHG_00665	1.1e-311	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
MHKMKOHG_00666	3.9e-217	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MHKMKOHG_00667	1.03e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
MHKMKOHG_00668	4.36e-143	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
MHKMKOHG_00669	6.45e-222	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHKMKOHG_00670	3.8e-154	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
MHKMKOHG_00671	3.8e-199	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
MHKMKOHG_00672	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
MHKMKOHG_00673	6.72e-185	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MHKMKOHG_00674	6.25e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_00675	1.86e-244	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MHKMKOHG_00676	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
MHKMKOHG_00677	1.51e-189	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
MHKMKOHG_00679	1.17e-46	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
MHKMKOHG_00680	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MHKMKOHG_00681	2.56e-307	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MHKMKOHG_00682	7.66e-193	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHKMKOHG_00683	7.99e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MHKMKOHG_00684	2.11e-256	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MHKMKOHG_00685	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MHKMKOHG_00686	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MHKMKOHG_00688	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MHKMKOHG_00689	1.32e-49	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MHKMKOHG_00690	1.01e-47	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHKMKOHG_00691	8.42e-11	-	-	-	K	-	-	-	PFAM helix-turn-helix domain protein
MHKMKOHG_00692	5.8e-18	-	-	-	-	-	-	-	-
MHKMKOHG_00694	4.84e-96	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
MHKMKOHG_00696	2.74e-54	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MHKMKOHG_00697	1.91e-182	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
MHKMKOHG_00698	2.26e-164	nicK	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
MHKMKOHG_00701	4.03e-77	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
MHKMKOHG_00703	0.0	yddE	-	-	S	-	-	-	AAA-like domain
MHKMKOHG_00706	1.29e-93	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
MHKMKOHG_00707	1.31e-141	-	-	-	M	-	-	-	Lysozyme-like
MHKMKOHG_00710	4.95e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
MHKMKOHG_00711	2.73e-176	-	-	-	L	-	-	-	Phage integrase family
MHKMKOHG_00712	6.07e-32	-	-	-	-	-	-	-	-
MHKMKOHG_00713	3.52e-124	-	-	-	KT	-	-	-	Belongs to the MT-A70-like family
MHKMKOHG_00714	5.36e-68	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MHKMKOHG_00715	9.15e-77	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MHKMKOHG_00716	6.6e-295	-	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
MHKMKOHG_00717	2.12e-234	-	-	-	K	ko:K07467	-	ko00000	Replication initiation factor
MHKMKOHG_00718	1.39e-40	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MHKMKOHG_00719	6e-113	-	-	-	-	-	-	-	-
MHKMKOHG_00720	8.13e-104	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
MHKMKOHG_00721	8.24e-81	-	-	-	-	-	-	-	-
MHKMKOHG_00722	1.38e-80	-	-	-	S	-	-	-	TcpE family
MHKMKOHG_00723	0.0	-	-	-	S	-	-	-	AAA-like domain
MHKMKOHG_00724	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
MHKMKOHG_00725	1.07e-219	yddH	-	-	M	-	-	-	Lysozyme-like
MHKMKOHG_00726	6.02e-162	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
MHKMKOHG_00727	3.11e-182	-	-	-	L	ko:K07459	-	ko00000	ATP-dependent endonuclease of the OLD
MHKMKOHG_00728	2.18e-118	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase activity
MHKMKOHG_00729	2.81e-112	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MHKMKOHG_00730	9.3e-158	-	-	-	S	-	-	-	SnoaL-like domain
MHKMKOHG_00731	1.05e-196	tet1	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major facilitator superfamily
MHKMKOHG_00732	2.48e-74	-	-	-	K	-	-	-	Sigma-70, region 4
MHKMKOHG_00733	5.98e-45	-	-	-	S	-	-	-	Helix-turn-helix domain
MHKMKOHG_00734	4.13e-18	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
MHKMKOHG_00735	4.39e-231	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MHKMKOHG_00736	3.03e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_00737	7.81e-316	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MHKMKOHG_00738	1.01e-268	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MHKMKOHG_00739	1.2e-165	yebC	-	-	M	-	-	-	Membrane
MHKMKOHG_00741	7.62e-120	yebE	-	-	S	-	-	-	UPF0316 protein
MHKMKOHG_00742	7.68e-39	yebG	-	-	S	-	-	-	NETI protein
MHKMKOHG_00743	1.87e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHKMKOHG_00744	1.99e-281	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHKMKOHG_00745	1.05e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHKMKOHG_00746	4.62e-164	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MHKMKOHG_00747	8.96e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHKMKOHG_00748	7.47e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHKMKOHG_00749	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHKMKOHG_00750	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHKMKOHG_00751	5.96e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MHKMKOHG_00752	3.89e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHKMKOHG_00753	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MHKMKOHG_00754	2.12e-293	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MHKMKOHG_00755	5e-81	-	-	-	K	-	-	-	helix_turn_helix ASNC type
MHKMKOHG_00756	9.21e-172	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
MHKMKOHG_00757	2.32e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
MHKMKOHG_00758	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MHKMKOHG_00759	1.85e-241	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
MHKMKOHG_00760	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_00761	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
MHKMKOHG_00762	5.04e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MHKMKOHG_00763	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MHKMKOHG_00764	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHKMKOHG_00765	1.59e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MHKMKOHG_00766	1.83e-232	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
MHKMKOHG_00767	7.98e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MHKMKOHG_00768	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHKMKOHG_00769	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHKMKOHG_00770	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHKMKOHG_00771	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHKMKOHG_00772	8.3e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_00773	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MHKMKOHG_00774	8.56e-217	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHKMKOHG_00775	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHKMKOHG_00776	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
MHKMKOHG_00777	5.95e-95	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	PFAM restriction modification system DNA specificity domain
MHKMKOHG_00778	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
MHKMKOHG_00779	2.2e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
MHKMKOHG_00780	1.53e-102	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MHKMKOHG_00781	1.14e-105	-	-	-	S	-	-	-	Protein of unknown function, DUF600
MHKMKOHG_00782	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
MHKMKOHG_00783	4.43e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MHKMKOHG_00785	3.96e-138	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MHKMKOHG_00786	1.32e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
MHKMKOHG_00787	1.34e-60	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
MHKMKOHG_00788	4.26e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
MHKMKOHG_00789	1.88e-112	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MHKMKOHG_00791	1.26e-147	yetF	-	-	S	-	-	-	membrane
MHKMKOHG_00792	4.35e-70	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MHKMKOHG_00793	4.96e-83	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKMKOHG_00794	3.41e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHKMKOHG_00795	9.52e-30	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MHKMKOHG_00796	1.5e-72	-	-	-	H	-	-	-	riboflavin kinase activity
MHKMKOHG_00797	5.15e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MHKMKOHG_00798	1.3e-111	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_00799	1.36e-245	yetM	-	-	CH	-	-	-	FAD binding domain
MHKMKOHG_00800	7.97e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MHKMKOHG_00801	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MHKMKOHG_00803	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MHKMKOHG_00804	1.7e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
MHKMKOHG_00805	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
MHKMKOHG_00806	2.78e-222	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MHKMKOHG_00807	1.88e-271	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
MHKMKOHG_00808	1.62e-228	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
MHKMKOHG_00809	4.78e-272	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_00810	2.1e-306	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
MHKMKOHG_00811	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKMKOHG_00812	3.69e-165	yfmS	-	-	NT	-	-	-	chemotaxis protein
MHKMKOHG_00813	1.93e-211	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MHKMKOHG_00814	7.17e-258	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHKMKOHG_00815	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHKMKOHG_00816	8.36e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
MHKMKOHG_00817	4.34e-249	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
MHKMKOHG_00818	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHKMKOHG_00819	3.3e-260	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MHKMKOHG_00820	9.68e-231	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
MHKMKOHG_00821	1.39e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
MHKMKOHG_00822	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MHKMKOHG_00823	1.51e-297	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MHKMKOHG_00824	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MHKMKOHG_00828	6.47e-93	M1-820	-	-	Q	-	-	-	Collagen triple helix repeat (20 copies)
MHKMKOHG_00829	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
MHKMKOHG_00830	2.26e-189	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MHKMKOHG_00831	0.0	-	-	-	M	-	-	-	cell wall anchor domain
MHKMKOHG_00832	4.77e-105	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MHKMKOHG_00833	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MHKMKOHG_00834	2.02e-147	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MHKMKOHG_00835	2.35e-218	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MHKMKOHG_00836	1.06e-282	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MHKMKOHG_00837	1.61e-181	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHKMKOHG_00838	9.97e-269	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MHKMKOHG_00839	4.43e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MHKMKOHG_00840	1.9e-153	yflK	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_00841	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
MHKMKOHG_00842	5.69e-26	yflI	-	-	-	-	-	-	-
MHKMKOHG_00843	1.38e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MHKMKOHG_00844	1.05e-174	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MHKMKOHG_00845	2.4e-313	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MHKMKOHG_00846	1.86e-95	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
MHKMKOHG_00847	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MHKMKOHG_00848	6.69e-81	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
MHKMKOHG_00849	2.79e-102	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MHKMKOHG_00850	6.73e-51	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MHKMKOHG_00851	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
MHKMKOHG_00852	3.52e-310	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_00853	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MHKMKOHG_00854	1.18e-161	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MHKMKOHG_00855	4.67e-155	frp	-	-	C	-	-	-	nitroreductase
MHKMKOHG_00856	6.13e-158	yibF	-	-	S	-	-	-	YibE/F-like protein
MHKMKOHG_00857	2.44e-238	yibE	-	-	S	-	-	-	YibE/F-like protein
MHKMKOHG_00858	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MHKMKOHG_00859	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MHKMKOHG_00860	4.44e-230	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHKMKOHG_00861	3.96e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHKMKOHG_00862	3.47e-166	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHKMKOHG_00863	2.03e-244	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_00864	1.66e-38	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MHKMKOHG_00865	6.36e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHKMKOHG_00866	4.68e-64	yfkI	-	-	S	-	-	-	gas vesicle protein
MHKMKOHG_00867	7.59e-183	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MHKMKOHG_00868	8.58e-271	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_00869	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
MHKMKOHG_00870	1.23e-180	yfkD	-	-	S	-	-	-	YfkD-like protein
MHKMKOHG_00871	9.64e-185	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
MHKMKOHG_00872	3.82e-278	yfkA	-	-	S	-	-	-	YfkB-like domain
MHKMKOHG_00873	7.99e-37	yfjT	-	-	-	-	-	-	-
MHKMKOHG_00874	4.19e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MHKMKOHG_00875	3.56e-180	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MHKMKOHG_00877	5.27e-235	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
MHKMKOHG_00878	4.16e-200	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MHKMKOHG_00880	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHKMKOHG_00882	1.36e-71	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
MHKMKOHG_00883	1.44e-83	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MHKMKOHG_00884	1.44e-93	-	-	-	-	-	-	-	-
MHKMKOHG_00886	1.11e-87	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHKMKOHG_00887	4.73e-72	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MHKMKOHG_00888	4.6e-95	drrA	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MHKMKOHG_00889	7.49e-87	-	-	-	CP	-	-	-	ABC-2 family transporter protein
MHKMKOHG_00890	2.32e-165	-	-	-	C	-	-	-	alcohol dehydrogenase
MHKMKOHG_00891	1.06e-59	-	-	-	S	-	-	-	YfzA-like protein
MHKMKOHG_00892	1.93e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHKMKOHG_00893	2.86e-102	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
MHKMKOHG_00894	2.08e-239	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHKMKOHG_00895	5.46e-235	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHKMKOHG_00896	7.49e-263	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHKMKOHG_00897	6.01e-305	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHKMKOHG_00898	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MHKMKOHG_00899	3.29e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
MHKMKOHG_00900	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHKMKOHG_00901	1.28e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MHKMKOHG_00902	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_00903	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
MHKMKOHG_00904	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MHKMKOHG_00905	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MHKMKOHG_00906	7.86e-82	yfiD3	-	-	S	-	-	-	DoxX
MHKMKOHG_00907	5.43e-195	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MHKMKOHG_00908	9.06e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHKMKOHG_00909	1e-119	padR	-	-	K	-	-	-	transcriptional
MHKMKOHG_00910	9.06e-129	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MHKMKOHG_00911	1.96e-222	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MHKMKOHG_00912	1.37e-59	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MHKMKOHG_00913	2.9e-122	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MHKMKOHG_00914	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
MHKMKOHG_00915	8.25e-101	yfiV	-	-	K	-	-	-	transcriptional
MHKMKOHG_00916	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHKMKOHG_00917	1.22e-191	yfhB	-	-	S	-	-	-	PhzF family
MHKMKOHG_00918	6.23e-133	yfhC	-	-	C	-	-	-	nitroreductase
MHKMKOHG_00919	6.01e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
MHKMKOHG_00921	4.54e-210	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MHKMKOHG_00922	1.95e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MHKMKOHG_00923	4.6e-60	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MHKMKOHG_00924	2.74e-266	yfhI	-	-	EGP	-	-	-	-transporter
MHKMKOHG_00926	3.43e-207	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
MHKMKOHG_00927	1.49e-58	yfhJ	-	-	S	-	-	-	WVELL protein
MHKMKOHG_00928	5.99e-95	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
MHKMKOHG_00929	5.95e-50	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
MHKMKOHG_00930	1.9e-172	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MHKMKOHG_00931	4.51e-235	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHKMKOHG_00932	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MHKMKOHG_00933	2.48e-228	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MHKMKOHG_00934	7.75e-258	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MHKMKOHG_00935	4.23e-49	yfhS	-	-	-	-	-	-	-
MHKMKOHG_00936	1.73e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_00937	9.58e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MHKMKOHG_00938	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
MHKMKOHG_00939	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MHKMKOHG_00940	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MHKMKOHG_00941	1.76e-237	ygaE	-	-	S	-	-	-	Membrane
MHKMKOHG_00942	3.13e-310	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MHKMKOHG_00943	3.83e-109	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MHKMKOHG_00944	6.8e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MHKMKOHG_00945	1.1e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
MHKMKOHG_00946	2.08e-208	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
MHKMKOHG_00947	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_00964	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
MHKMKOHG_00965	3.38e-158	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MHKMKOHG_00966	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MHKMKOHG_00967	3.15e-313	ygaK	-	-	C	-	-	-	Berberine and berberine like
MHKMKOHG_00969	2.5e-286	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
MHKMKOHG_00970	2.71e-184	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHKMKOHG_00971	1.07e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKMKOHG_00972	1.56e-169	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_00973	4.45e-166	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_00974	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MHKMKOHG_00975	6.85e-227	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
MHKMKOHG_00976	4.82e-175	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MHKMKOHG_00977	1.04e-221	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
MHKMKOHG_00978	1.12e-183	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MHKMKOHG_00979	8.25e-271	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MHKMKOHG_00981	1.62e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHKMKOHG_00982	1.56e-98	ygaO	-	-	-	-	-	-	-
MHKMKOHG_00983	1.9e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_00985	5.45e-138	yhzB	-	-	S	-	-	-	B3/4 domain
MHKMKOHG_00986	4.5e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHKMKOHG_00987	2.06e-216	yhbB	-	-	S	-	-	-	Putative amidase domain
MHKMKOHG_00988	2.31e-110	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHKMKOHG_00989	9.59e-132	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
MHKMKOHG_00990	1.02e-75	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MHKMKOHG_00991	6.48e-86	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
MHKMKOHG_00992	1.23e-07	-	-	-	-	-	-	-	-
MHKMKOHG_00993	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MHKMKOHG_00994	2.12e-276	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MHKMKOHG_00995	1.28e-92	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
MHKMKOHG_00996	2.98e-130	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
MHKMKOHG_00997	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MHKMKOHG_00998	7.47e-128	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MHKMKOHG_00999	5.09e-66	yhcC	-	-	-	-	-	-	-
MHKMKOHG_01000	4.29e-64	-	-	-	-	-	-	-	-
MHKMKOHG_01001	8.78e-77	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01002	5.37e-148	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_01003	8.81e-211	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_01004	4.59e-202	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHKMKOHG_01005	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MHKMKOHG_01006	1.54e-167	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MHKMKOHG_01007	5.06e-173	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
MHKMKOHG_01008	1.44e-290	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKMKOHG_01009	2.84e-26	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHKMKOHG_01010	3.1e-61	yhcM	-	-	-	-	-	-	-
MHKMKOHG_01011	2.12e-117	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHKMKOHG_01012	5.43e-197	yhcP	-	-	-	-	-	-	-
MHKMKOHG_01013	4.1e-147	yhcQ	-	-	M	-	-	-	Spore coat protein
MHKMKOHG_01014	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHKMKOHG_01015	9.47e-130	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MHKMKOHG_01016	2.61e-206	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MHKMKOHG_01017	1.88e-83	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
MHKMKOHG_01018	5.88e-89	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
MHKMKOHG_01019	1.33e-158	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MHKMKOHG_01020	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHKMKOHG_01021	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHKMKOHG_01022	2.75e-130	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MHKMKOHG_01023	2.6e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MHKMKOHG_01024	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHKMKOHG_01025	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MHKMKOHG_01026	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MHKMKOHG_01027	4.32e-244	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_01028	7.97e-139	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHKMKOHG_01029	3.13e-103	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
MHKMKOHG_01030	1.16e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
MHKMKOHG_01031	2.33e-68	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MHKMKOHG_01032	1.88e-279	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MHKMKOHG_01033	1.49e-93	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MHKMKOHG_01034	3.85e-312	ygxB	-	-	M	-	-	-	Conserved TM helix
MHKMKOHG_01035	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MHKMKOHG_01036	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MHKMKOHG_01037	2.28e-166	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MHKMKOHG_01038	5.67e-200	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01039	8.91e-250	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MHKMKOHG_01040	1.77e-202	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_01041	1.1e-311	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
MHKMKOHG_01042	1.33e-263	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHKMKOHG_01043	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
MHKMKOHG_01044	2.88e-249	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
MHKMKOHG_01045	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_01046	4.04e-136	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHKMKOHG_01047	2.66e-305	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHKMKOHG_01048	2.3e-91	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
MHKMKOHG_01049	3.27e-276	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MHKMKOHG_01050	5.78e-287	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHKMKOHG_01051	7.77e-314	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHKMKOHG_01052	1.68e-69	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHKMKOHG_01053	4.22e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHKMKOHG_01054	1.87e-158	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MHKMKOHG_01055	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
MHKMKOHG_01056	3.79e-252	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MHKMKOHG_01057	4.47e-175	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHKMKOHG_01058	5.62e-191	nodB1	-	-	G	-	-	-	deacetylase
MHKMKOHG_01059	1.49e-191	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MHKMKOHG_01060	4.2e-106	pksA	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_01061	1.17e-118	ymcC	-	-	S	-	-	-	Membrane
MHKMKOHG_01062	9.73e-108	-	-	-	T	-	-	-	universal stress protein
MHKMKOHG_01063	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MHKMKOHG_01064	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MHKMKOHG_01065	5.82e-128	yheG	-	-	GM	-	-	-	NAD(P)H-binding
MHKMKOHG_01067	1.91e-38	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MHKMKOHG_01068	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
MHKMKOHG_01069	9.2e-317	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MHKMKOHG_01070	2.22e-256	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
MHKMKOHG_01071	1.27e-253	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MHKMKOHG_01072	2.72e-69	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MHKMKOHG_01073	2.49e-197	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MHKMKOHG_01074	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
MHKMKOHG_01075	4.94e-310	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
MHKMKOHG_01076	6.38e-263	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
MHKMKOHG_01077	1.53e-112	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MHKMKOHG_01079	1.32e-171	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
MHKMKOHG_01080	1.47e-21	-	-	-	S	-	-	-	YhzD-like protein
MHKMKOHG_01081	3.45e-209	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_01082	7.64e-274	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MHKMKOHG_01083	1.55e-292	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
MHKMKOHG_01084	0.0	yhaN	-	-	L	-	-	-	AAA domain
MHKMKOHG_01085	2.38e-224	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MHKMKOHG_01086	8.23e-43	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MHKMKOHG_01087	7.87e-183	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHKMKOHG_01088	3.56e-121	yhaK	-	-	S	-	-	-	Putative zincin peptidase
MHKMKOHG_01089	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
MHKMKOHG_01090	4.54e-144	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MHKMKOHG_01091	1.58e-53	yhaH	-	-	S	-	-	-	YtxH-like protein
MHKMKOHG_01092	2.55e-24	-	-	-	-	-	-	-	-
MHKMKOHG_01093	1.59e-97	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
MHKMKOHG_01094	6.07e-252	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHKMKOHG_01095	1.17e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MHKMKOHG_01096	4.29e-173	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MHKMKOHG_01097	1.68e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MHKMKOHG_01098	1.26e-154	ecsC	-	-	S	-	-	-	EcsC protein family
MHKMKOHG_01099	4.81e-274	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MHKMKOHG_01100	9.54e-303	yhfA	-	-	C	-	-	-	membrane
MHKMKOHG_01101	4.23e-115	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MHKMKOHG_01102	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MHKMKOHG_01103	1.31e-252	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MHKMKOHG_01104	3.4e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MHKMKOHG_01105	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MHKMKOHG_01106	5.15e-130	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01107	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MHKMKOHG_01109	2.89e-226	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHKMKOHG_01111	7.07e-249	yhfE	-	-	G	-	-	-	peptidase M42
MHKMKOHG_01112	2.64e-286	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHKMKOHG_01113	9.76e-173	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MHKMKOHG_01114	1.85e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MHKMKOHG_01115	3.92e-137	yhfK	-	-	GM	-	-	-	NmrA-like family
MHKMKOHG_01116	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MHKMKOHG_01117	9.31e-84	yhfM	-	-	-	-	-	-	-
MHKMKOHG_01118	4.64e-294	yhfN	-	-	O	-	-	-	Peptidase M48
MHKMKOHG_01119	1.24e-258	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHKMKOHG_01120	5.93e-162	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MHKMKOHG_01121	3.35e-131	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MHKMKOHG_01122	3.46e-244	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MHKMKOHG_01123	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MHKMKOHG_01124	2.71e-109	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MHKMKOHG_01125	2.08e-272	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MHKMKOHG_01126	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MHKMKOHG_01127	2.73e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_01128	5.49e-42	yhzC	-	-	S	-	-	-	IDEAL
MHKMKOHG_01129	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
MHKMKOHG_01130	1.31e-77	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MHKMKOHG_01131	2.23e-214	-	-	-	S	-	-	-	Acetyltransferase, GNAT family
MHKMKOHG_01132	3.92e-157	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
MHKMKOHG_01133	7.11e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
MHKMKOHG_01134	3.19e-59	-	-	-	S	-	-	-	Belongs to the UPF0145 family
MHKMKOHG_01135	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHKMKOHG_01136	5.59e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MHKMKOHG_01137	6.59e-76	yhjD	-	-	-	-	-	-	-
MHKMKOHG_01138	8.02e-136	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
MHKMKOHG_01139	3.72e-116	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHKMKOHG_01140	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
MHKMKOHG_01141	4.02e-119	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_01142	1.37e-252	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
MHKMKOHG_01143	1.34e-261	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_01144	1.02e-137	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
MHKMKOHG_01145	1.72e-108	yhjR	-	-	S	-	-	-	Rubrerythrin
MHKMKOHG_01146	3.08e-152	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
MHKMKOHG_01147	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
MHKMKOHG_01148	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MHKMKOHG_01149	2.61e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHKMKOHG_01150	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
MHKMKOHG_01151	3.36e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
MHKMKOHG_01152	5.49e-42	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
MHKMKOHG_01153	1.43e-78	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
MHKMKOHG_01154	1.44e-31	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
MHKMKOHG_01155	3.28e-104	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
MHKMKOHG_01156	1.01e-44	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
MHKMKOHG_01157	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
MHKMKOHG_01158	2.45e-13	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MHKMKOHG_01159	1.3e-210	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MHKMKOHG_01160	4.48e-78	yisL	-	-	S	-	-	-	UPF0344 protein
MHKMKOHG_01161	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHKMKOHG_01162	5.25e-115	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MHKMKOHG_01163	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MHKMKOHG_01164	4.48e-152	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
MHKMKOHG_01165	2.92e-308	yisQ	-	-	V	-	-	-	Mate efflux family protein
MHKMKOHG_01166	2.51e-201	yisR	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_01167	8.2e-181	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MHKMKOHG_01168	6.95e-197	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MHKMKOHG_01169	3.8e-102	yisT	-	-	S	-	-	-	DinB family
MHKMKOHG_01170	1.2e-95	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MHKMKOHG_01171	6.72e-237	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKMKOHG_01172	1.69e-91	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MHKMKOHG_01173	1.13e-98	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MHKMKOHG_01174	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHKMKOHG_01175	7.44e-78	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
MHKMKOHG_01176	9.46e-199	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MHKMKOHG_01177	8.05e-187	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
MHKMKOHG_01178	1.23e-287	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MHKMKOHG_01179	3.41e-296	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MHKMKOHG_01181	5.67e-196	yitS	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_01182	1.88e-188	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHKMKOHG_01183	8.76e-104	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
MHKMKOHG_01184	4.3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
MHKMKOHG_01185	1.49e-11	-	-	-	-	-	-	-	-
MHKMKOHG_01186	2.71e-192	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MHKMKOHG_01187	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MHKMKOHG_01188	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MHKMKOHG_01189	3.29e-92	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MHKMKOHG_01190	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
MHKMKOHG_01191	1.33e-118	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
MHKMKOHG_01192	4.41e-247	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHKMKOHG_01193	2.74e-285	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHKMKOHG_01194	1.78e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MHKMKOHG_01195	2.64e-266	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MHKMKOHG_01196	2.18e-246	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MHKMKOHG_01197	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MHKMKOHG_01198	8.46e-219	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHKMKOHG_01199	2.07e-38	yjzC	-	-	S	-	-	-	YjzC-like protein
MHKMKOHG_01200	3.71e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MHKMKOHG_01201	1.62e-171	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MHKMKOHG_01202	5.79e-126	yjaV	-	-	-	-	-	-	-
MHKMKOHG_01203	8.66e-209	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
MHKMKOHG_01204	3.74e-36	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
MHKMKOHG_01205	1.46e-37	yjzB	-	-	-	-	-	-	-
MHKMKOHG_01206	1.26e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHKMKOHG_01207	7.15e-296	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHKMKOHG_01208	5.83e-178	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MHKMKOHG_01209	4.64e-229	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_01210	5.46e-233	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_01211	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MHKMKOHG_01212	8.55e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKMKOHG_01213	7.81e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKMKOHG_01214	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MHKMKOHG_01215	8.74e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MHKMKOHG_01216	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHKMKOHG_01217	2.08e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKMKOHG_01218	8.44e-209	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKMKOHG_01219	7.98e-252	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_01220	1.22e-217	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_01221	2.23e-282	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
MHKMKOHG_01222	8.52e-130	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHKMKOHG_01223	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHKMKOHG_01224	1.32e-139	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
MHKMKOHG_01225	2.3e-148	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHKMKOHG_01226	9.33e-256	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MHKMKOHG_01227	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MHKMKOHG_01228	1.28e-26	-	-	-	-	-	-	-	-
MHKMKOHG_01229	9.23e-215	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MHKMKOHG_01230	6.79e-91	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
MHKMKOHG_01231	2.31e-138	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHKMKOHG_01232	6.93e-117	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_01233	3.37e-79	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MHKMKOHG_01234	3.67e-138	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MHKMKOHG_01235	6.92e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHKMKOHG_01236	9.83e-204	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MHKMKOHG_01237	1.1e-176	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MHKMKOHG_01238	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHKMKOHG_01239	2.06e-170	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHKMKOHG_01240	3.39e-131	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
MHKMKOHG_01241	8.33e-255	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MHKMKOHG_01242	2.63e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
MHKMKOHG_01243	1.48e-172	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHKMKOHG_01244	1.01e-227	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHKMKOHG_01245	2.56e-181	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MHKMKOHG_01246	1.38e-179	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MHKMKOHG_01247	4.29e-101	yjbX	-	-	S	-	-	-	Spore coat protein
MHKMKOHG_01248	3.35e-105	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
MHKMKOHG_01249	1.75e-120	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
MHKMKOHG_01250	3.55e-98	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MHKMKOHG_01251	1.02e-36	cotW	-	-	-	ko:K06341	-	ko00000	-
MHKMKOHG_01252	4.61e-69	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
MHKMKOHG_01253	1.69e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MHKMKOHG_01256	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MHKMKOHG_01257	1.05e-50	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
MHKMKOHG_01258	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHKMKOHG_01259	1.62e-44	-	-	-	-	-	-	-	-
MHKMKOHG_01260	1.6e-167	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
MHKMKOHG_01261	1.41e-154	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MHKMKOHG_01262	1.09e-165	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MHKMKOHG_01263	1.19e-45	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MHKMKOHG_01264	2.11e-92	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHKMKOHG_01265	4.03e-120	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MHKMKOHG_01266	8.87e-158	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MHKMKOHG_01267	2.18e-268	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MHKMKOHG_01268	1.67e-272	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MHKMKOHG_01270	5.37e-43	-	-	-	L	-	-	-	Phage integrase family
MHKMKOHG_01271	4.33e-42	-	-	-	-	-	-	-	-
MHKMKOHG_01272	8.82e-115	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MHKMKOHG_01273	4.58e-59	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	2-dehydropantoate 2-reductase
MHKMKOHG_01274	7.44e-61	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	2-dehydropantoate 2-reductase
MHKMKOHG_01277	2.92e-217	-	-	-	S	-	-	-	amine dehydrogenase activity
MHKMKOHG_01279	4.74e-38	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MHKMKOHG_01282	1.97e-17	-	-	-	-	-	-	-	-
MHKMKOHG_01284	2.15e-29	-	-	-	-	-	-	-	-
MHKMKOHG_01285	2.08e-30	-	-	-	-	-	-	-	-
MHKMKOHG_01288	1.3e-204	-	-	-	S	-	-	-	Putative amidase domain
MHKMKOHG_01289	1.2e-54	yjcN	-	-	-	-	-	-	-
MHKMKOHG_01292	1.37e-141	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
MHKMKOHG_01293	3.97e-43	yqaS	-	-	L	-	-	-	DNA packaging
MHKMKOHG_01294	1.44e-200	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MHKMKOHG_01295	8.96e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MHKMKOHG_01296	5.5e-302	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
MHKMKOHG_01297	3.81e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_01298	1.05e-274	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MHKMKOHG_01299	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHKMKOHG_01300	5.16e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_01301	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHKMKOHG_01302	1.39e-177	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MHKMKOHG_01303	7.94e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MHKMKOHG_01304	3.25e-44	-	-	-	-	-	-	-	-
MHKMKOHG_01305	4.16e-69	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_01306	3.93e-133	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MHKMKOHG_01307	2.62e-29	yjfB	-	-	S	-	-	-	Putative motility protein
MHKMKOHG_01308	4.94e-80	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
MHKMKOHG_01309	4.73e-121	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
MHKMKOHG_01310	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MHKMKOHG_01311	7.9e-111	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MHKMKOHG_01312	8.02e-276	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHKMKOHG_01313	1.32e-273	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MHKMKOHG_01314	1.73e-40	-	-	-	-	-	-	-	-
MHKMKOHG_01315	1.44e-180	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MHKMKOHG_01316	4.93e-150	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
MHKMKOHG_01317	5.48e-160	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_01318	1.47e-220	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MHKMKOHG_01319	2.18e-112	yjlB	-	-	S	-	-	-	Cupin domain
MHKMKOHG_01320	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MHKMKOHG_01321	8.37e-278	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MHKMKOHG_01322	2.47e-98	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MHKMKOHG_01323	3.99e-232	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MHKMKOHG_01324	1.01e-206	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MHKMKOHG_01325	4.5e-113	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MHKMKOHG_01326	2.61e-166	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHKMKOHG_01328	3.59e-164	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHKMKOHG_01329	2.31e-100	yjoA	-	-	S	-	-	-	DinB family
MHKMKOHG_01330	3.13e-274	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MHKMKOHG_01332	1.98e-209	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MHKMKOHG_01333	3.19e-79	yjqA	-	-	S	-	-	-	Bacterial PH domain
MHKMKOHG_01334	3.82e-128	yjqB	-	-	S	-	-	-	phage-related replication protein
MHKMKOHG_01335	2.86e-139	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
MHKMKOHG_01336	1.27e-72	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MHKMKOHG_01338	8.99e-138	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
MHKMKOHG_01339	2.17e-170	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
MHKMKOHG_01343	2.7e-106	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MHKMKOHG_01344	7.26e-137	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
MHKMKOHG_01345	8.8e-261	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
MHKMKOHG_01346	2.56e-304	xkdE3	-	-	S	-	-	-	portal protein
MHKMKOHG_01347	8.47e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
MHKMKOHG_01348	1.67e-202	xkdG	-	-	S	-	-	-	Phage capsid family
MHKMKOHG_01349	1.26e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
MHKMKOHG_01351	1.98e-76	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MHKMKOHG_01352	2.59e-75	xkdJ	-	-	-	-	-	-	-
MHKMKOHG_01353	3.86e-21	-	-	-	-	-	-	-	-
MHKMKOHG_01354	3.28e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
MHKMKOHG_01355	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
MHKMKOHG_01356	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
MHKMKOHG_01357	4.33e-27	-	-	-	-	-	-	-	-
MHKMKOHG_01358	1.49e-256	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
MHKMKOHG_01359	6.56e-145	xkdP	-	-	S	-	-	-	Lysin motif
MHKMKOHG_01360	2.78e-208	xkdQ	-	-	G	-	-	-	NLP P60 protein
MHKMKOHG_01361	3.05e-44	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
MHKMKOHG_01362	4.98e-43	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MHKMKOHG_01363	2.55e-23	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
MHKMKOHG_01364	2.53e-211	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MHKMKOHG_01365	2.77e-110	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
MHKMKOHG_01366	1.48e-36	-	-	-	-	-	-	-	-
MHKMKOHG_01367	0.0	-	-	-	-	-	-	-	-
MHKMKOHG_01368	1.6e-49	xkdW	-	-	S	-	-	-	XkdW protein
MHKMKOHG_01369	2.74e-23	xkdX	-	-	-	-	-	-	-
MHKMKOHG_01370	2.51e-132	xepA	-	-	-	-	-	-	-
MHKMKOHG_01371	9.15e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
MHKMKOHG_01372	2.62e-49	xhlB	-	-	S	-	-	-	SPP1 phage holin
MHKMKOHG_01373	5.72e-205	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MHKMKOHG_01374	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
MHKMKOHG_01375	4.26e-169	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MHKMKOHG_01376	2.36e-224	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
MHKMKOHG_01377	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
MHKMKOHG_01378	3.66e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MHKMKOHG_01379	1.75e-227	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MHKMKOHG_01380	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHKMKOHG_01381	8.64e-227	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHKMKOHG_01383	6.25e-268	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHKMKOHG_01384	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
MHKMKOHG_01385	4.88e-197	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MHKMKOHG_01386	2.68e-202	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKMKOHG_01387	1.12e-218	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHKMKOHG_01388	2.58e-231	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_01389	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHKMKOHG_01390	5.18e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MHKMKOHG_01391	6.68e-243	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MHKMKOHG_01392	1.05e-199	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHKMKOHG_01393	2.03e-225	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_01394	6.84e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MHKMKOHG_01395	7.5e-182	ykgA	-	-	E	-	-	-	Amidinotransferase
MHKMKOHG_01396	2.16e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
MHKMKOHG_01397	6.07e-120	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MHKMKOHG_01398	1.54e-64	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MHKMKOHG_01399	1.73e-64	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MHKMKOHG_01400	8.86e-213	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MHKMKOHG_01401	5.43e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHKMKOHG_01402	5.73e-283	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHKMKOHG_01403	7.71e-90	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MHKMKOHG_01404	6.88e-102	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
MHKMKOHG_01405	4.36e-89	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MHKMKOHG_01406	5.11e-71	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MHKMKOHG_01408	2.92e-258	-	-	-	M	-	-	-	Glycosyl transferase family 2
MHKMKOHG_01409	5.92e-139	-	-	-	K	-	-	-	Collagen triple helix repeat
MHKMKOHG_01410	2.41e-262	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_01411	1.82e-153	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MHKMKOHG_01412	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHKMKOHG_01413	2.76e-221	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHKMKOHG_01414	8.85e-181	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHKMKOHG_01415	4.52e-162	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MHKMKOHG_01416	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_01417	7.4e-123	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MHKMKOHG_01418	2.63e-302	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
MHKMKOHG_01420	7.93e-306	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MHKMKOHG_01421	3.53e-69	tnrA	-	-	K	-	-	-	transcriptional
MHKMKOHG_01422	2.24e-23	-	-	-	-	-	-	-	-
MHKMKOHG_01423	1.46e-34	ykoL	-	-	-	-	-	-	-
MHKMKOHG_01424	3.16e-104	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MHKMKOHG_01425	2.57e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MHKMKOHG_01426	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MHKMKOHG_01427	4.47e-198	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MHKMKOHG_01428	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
MHKMKOHG_01429	2.44e-123	ykoX	-	-	S	-	-	-	membrane-associated protein
MHKMKOHG_01430	5.75e-164	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MHKMKOHG_01431	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKMKOHG_01432	3.68e-223	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
MHKMKOHG_01433	3.31e-35	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
MHKMKOHG_01434	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
MHKMKOHG_01435	4.28e-198	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MHKMKOHG_01436	1.65e-302	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MHKMKOHG_01437	2.76e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MHKMKOHG_01438	5.59e-26	ykzE	-	-	-	-	-	-	-
MHKMKOHG_01439	1.59e-242	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
MHKMKOHG_01440	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_01441	7.24e-102	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHKMKOHG_01443	2.02e-247	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MHKMKOHG_01444	6.89e-278	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MHKMKOHG_01445	5.12e-176	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MHKMKOHG_01446	1.3e-284	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MHKMKOHG_01447	5.65e-282	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MHKMKOHG_01448	2.92e-169	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MHKMKOHG_01449	2.81e-141	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MHKMKOHG_01450	5.42e-117	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MHKMKOHG_01453	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MHKMKOHG_01454	3.34e-101	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MHKMKOHG_01455	2.8e-161	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MHKMKOHG_01456	1.2e-175	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MHKMKOHG_01457	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MHKMKOHG_01458	3.06e-222	ykvI	-	-	S	-	-	-	membrane
MHKMKOHG_01459	4.92e-233	-	-	-	-	-	-	-	-
MHKMKOHG_01460	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MHKMKOHG_01461	8.88e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MHKMKOHG_01462	5.67e-176	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MHKMKOHG_01463	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MHKMKOHG_01464	7.02e-58	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
MHKMKOHG_01465	1.56e-34	ykvS	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_01466	2.92e-38	-	-	-	-	-	-	-	-
MHKMKOHG_01467	6.11e-135	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MHKMKOHG_01468	3.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKMKOHG_01469	8.87e-107	stoA	-	-	CO	-	-	-	thiol-disulfide
MHKMKOHG_01470	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MHKMKOHG_01471	9.11e-261	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MHKMKOHG_01473	1.03e-217	ykvZ	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_01474	1.54e-196	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MHKMKOHG_01475	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_01476	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MHKMKOHG_01477	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHKMKOHG_01478	1.22e-48	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01479	2.29e-252	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MHKMKOHG_01480	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHKMKOHG_01481	3.3e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MHKMKOHG_01482	3.34e-65	-	-	-	-	-	-	-	-
MHKMKOHG_01483	9.4e-165	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MHKMKOHG_01484	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MHKMKOHG_01485	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_01486	9e-273	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MHKMKOHG_01487	2.22e-15	-	-	-	-	-	-	-	-
MHKMKOHG_01488	1.3e-211	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MHKMKOHG_01489	1.45e-107	ykyB	-	-	S	-	-	-	YkyB-like protein
MHKMKOHG_01490	4.93e-303	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_01491	2.01e-113	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_01492	4.21e-187	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
MHKMKOHG_01493	2.29e-176	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_01495	1.74e-293	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MHKMKOHG_01496	2.11e-49	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_01497	1.4e-116	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
MHKMKOHG_01498	2.63e-36	ykzF	-	-	S	-	-	-	Antirepressor AbbA
MHKMKOHG_01499	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
MHKMKOHG_01500	1.08e-214	ccpC	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_01501	1.02e-113	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MHKMKOHG_01502	8.78e-207	ykuO	-	-	-	-	-	-	-
MHKMKOHG_01503	2.33e-98	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MHKMKOHG_01504	4.79e-128	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHKMKOHG_01505	1.22e-270	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHKMKOHG_01506	1.25e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MHKMKOHG_01507	1.17e-176	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MHKMKOHG_01509	1.29e-91	ykuV	-	-	CO	-	-	-	thiol-disulfide
MHKMKOHG_01510	3.55e-125	rok	-	-	K	-	-	-	Repressor of ComK
MHKMKOHG_01511	3.98e-199	yknT	-	-	-	ko:K06437	-	ko00000	-
MHKMKOHG_01512	6.65e-131	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MHKMKOHG_01513	4.32e-235	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MHKMKOHG_01514	1.72e-303	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MHKMKOHG_01515	7.51e-112	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MHKMKOHG_01516	7.17e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MHKMKOHG_01517	1.58e-41	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MHKMKOHG_01519	3.04e-129	yknW	-	-	S	-	-	-	Yip1 domain
MHKMKOHG_01520	2.98e-225	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHKMKOHG_01521	1.96e-156	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_01522	2.73e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MHKMKOHG_01523	8.9e-168	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01524	8.8e-210	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MHKMKOHG_01525	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHKMKOHG_01526	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHKMKOHG_01527	1.44e-47	ykoA	-	-	-	-	-	-	-
MHKMKOHG_01528	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MHKMKOHG_01529	9.75e-202	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHKMKOHG_01530	9.45e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MHKMKOHG_01531	7.7e-19	-	-	-	S	-	-	-	Uncharacterized protein YkpC
MHKMKOHG_01532	6.17e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MHKMKOHG_01533	7.46e-59	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
MHKMKOHG_01534	7.52e-300	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MHKMKOHG_01535	1.98e-192	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
MHKMKOHG_01536	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MHKMKOHG_01537	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MHKMKOHG_01538	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHKMKOHG_01539	7.4e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MHKMKOHG_01540	2.12e-178	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MHKMKOHG_01541	1.81e-127	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHKMKOHG_01542	4.93e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MHKMKOHG_01543	1.64e-126	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MHKMKOHG_01544	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHKMKOHG_01545	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHKMKOHG_01546	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
MHKMKOHG_01547	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHKMKOHG_01548	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHKMKOHG_01549	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHKMKOHG_01550	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHKMKOHG_01551	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
MHKMKOHG_01552	2.48e-253	-	-	-	V	-	-	-	Beta-lactamase
MHKMKOHG_01554	3.17e-260	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHKMKOHG_01555	2.38e-225	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHKMKOHG_01556	1.71e-300	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHKMKOHG_01557	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHKMKOHG_01558	6.84e-60	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
MHKMKOHG_01559	6.72e-173	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MHKMKOHG_01560	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MHKMKOHG_01561	1.29e-54	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MHKMKOHG_01562	4.72e-154	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MHKMKOHG_01563	7.89e-32	ykzI	-	-	-	-	-	-	-
MHKMKOHG_01564	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MHKMKOHG_01565	2.25e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
MHKMKOHG_01566	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
MHKMKOHG_01567	2.52e-220	ylaA	-	-	-	-	-	-	-
MHKMKOHG_01568	4.64e-53	ylaB	-	-	-	-	-	-	-
MHKMKOHG_01569	3.39e-112	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_01571	1.31e-55	ylaE	-	-	-	-	-	-	-
MHKMKOHG_01572	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MHKMKOHG_01573	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MHKMKOHG_01574	4.7e-60	-	-	-	S	-	-	-	YlaH-like protein
MHKMKOHG_01575	7.95e-45	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_01576	7.97e-131	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHKMKOHG_01577	4.29e-310	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MHKMKOHG_01578	4.45e-104	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MHKMKOHG_01579	1.94e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MHKMKOHG_01580	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MHKMKOHG_01581	3.73e-266	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHKMKOHG_01582	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHKMKOHG_01583	3.88e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MHKMKOHG_01584	1.2e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MHKMKOHG_01585	1.32e-249	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MHKMKOHG_01586	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHKMKOHG_01587	3.43e-141	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MHKMKOHG_01588	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MHKMKOHG_01589	3.17e-206	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MHKMKOHG_01590	1.96e-77	ylbA	-	-	S	-	-	-	YugN-like family
MHKMKOHG_01591	1.94e-95	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
MHKMKOHG_01592	5.56e-246	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MHKMKOHG_01593	2.72e-83	ylbD	-	-	S	-	-	-	Putative coat protein
MHKMKOHG_01594	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
MHKMKOHG_01595	3.73e-94	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MHKMKOHG_01596	4.62e-56	ylbG	-	-	S	-	-	-	UPF0298 protein
MHKMKOHG_01597	4.27e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MHKMKOHG_01598	2.38e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHKMKOHG_01599	1.16e-267	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MHKMKOHG_01600	2.03e-177	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MHKMKOHG_01601	4.48e-233	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MHKMKOHG_01602	1.64e-282	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MHKMKOHG_01603	4.69e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MHKMKOHG_01604	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MHKMKOHG_01605	1.93e-105	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MHKMKOHG_01606	6.58e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
MHKMKOHG_01607	8.05e-193	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHKMKOHG_01608	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MHKMKOHG_01609	9.07e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MHKMKOHG_01610	2.75e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHKMKOHG_01611	2.81e-67	ftsL	-	-	D	-	-	-	Essential cell division protein
MHKMKOHG_01612	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MHKMKOHG_01613	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MHKMKOHG_01614	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHKMKOHG_01615	2.36e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHKMKOHG_01616	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHKMKOHG_01617	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHKMKOHG_01618	1.63e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHKMKOHG_01619	2.63e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MHKMKOHG_01620	3.74e-170	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHKMKOHG_01621	3.7e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHKMKOHG_01622	4.32e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHKMKOHG_01623	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
MHKMKOHG_01624	3.59e-212	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MHKMKOHG_01625	3.64e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKMKOHG_01626	3.8e-178	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKMKOHG_01627	1.82e-183	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MHKMKOHG_01628	2.03e-309	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MHKMKOHG_01629	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
MHKMKOHG_01630	4.01e-198	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MHKMKOHG_01631	1.96e-156	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHKMKOHG_01632	8.91e-83	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHKMKOHG_01633	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MHKMKOHG_01634	1.14e-177	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MHKMKOHG_01635	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MHKMKOHG_01636	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHKMKOHG_01637	4.22e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MHKMKOHG_01638	8.42e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHKMKOHG_01639	7.29e-214	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MHKMKOHG_01640	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHKMKOHG_01641	6.33e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MHKMKOHG_01642	4.84e-203	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MHKMKOHG_01643	4.1e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHKMKOHG_01644	4.04e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MHKMKOHG_01645	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MHKMKOHG_01646	9.33e-177	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MHKMKOHG_01647	1.94e-217	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHKMKOHG_01648	1.17e-159	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHKMKOHG_01649	2.03e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHKMKOHG_01650	7.81e-178	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MHKMKOHG_01651	2.14e-222	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MHKMKOHG_01652	5.68e-280	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MHKMKOHG_01653	1.31e-140	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MHKMKOHG_01654	4.28e-178	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MHKMKOHG_01655	1.37e-176	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
MHKMKOHG_01656	1.85e-98	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MHKMKOHG_01657	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MHKMKOHG_01658	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MHKMKOHG_01659	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MHKMKOHG_01660	8e-194	yloC	-	-	S	-	-	-	stress-induced protein
MHKMKOHG_01661	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MHKMKOHG_01662	1.16e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MHKMKOHG_01663	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHKMKOHG_01664	8.14e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHKMKOHG_01665	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHKMKOHG_01666	4.8e-109	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHKMKOHG_01667	6.66e-215	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHKMKOHG_01668	1.7e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHKMKOHG_01669	3.58e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHKMKOHG_01670	8.15e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MHKMKOHG_01671	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MHKMKOHG_01672	2.96e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHKMKOHG_01673	1.69e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MHKMKOHG_01674	7.74e-146	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MHKMKOHG_01675	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MHKMKOHG_01676	2.12e-77	yloU	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_01677	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MHKMKOHG_01678	1.69e-152	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MHKMKOHG_01679	3.97e-200	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MHKMKOHG_01680	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHKMKOHG_01681	2.96e-119	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MHKMKOHG_01682	2.58e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHKMKOHG_01683	2.08e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHKMKOHG_01684	2.88e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MHKMKOHG_01685	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHKMKOHG_01686	2.48e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHKMKOHG_01687	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MHKMKOHG_01688	2.09e-221	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHKMKOHG_01689	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHKMKOHG_01690	2e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHKMKOHG_01691	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MHKMKOHG_01692	2.84e-48	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MHKMKOHG_01693	5.66e-79	ylqD	-	-	S	-	-	-	YlqD protein
MHKMKOHG_01694	5.07e-120	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHKMKOHG_01695	2.22e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MHKMKOHG_01696	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHKMKOHG_01697	5.95e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHKMKOHG_01698	3.1e-170	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHKMKOHG_01699	0.0	ylqG	-	-	-	-	-	-	-
MHKMKOHG_01700	9.86e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
MHKMKOHG_01701	1.66e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHKMKOHG_01702	7.59e-214	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHKMKOHG_01703	5.3e-209	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MHKMKOHG_01704	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHKMKOHG_01705	1.05e-311	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHKMKOHG_01706	1.42e-216	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MHKMKOHG_01707	1.43e-118	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHKMKOHG_01708	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHKMKOHG_01709	7.94e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MHKMKOHG_01710	3.14e-81	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MHKMKOHG_01711	1.46e-96	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MHKMKOHG_01712	1.51e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MHKMKOHG_01713	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MHKMKOHG_01714	3.52e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHKMKOHG_01715	6.92e-116	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MHKMKOHG_01716	8.24e-306	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MHKMKOHG_01717	2.17e-92	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
MHKMKOHG_01718	3.78e-76	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
MHKMKOHG_01719	1.3e-240	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
MHKMKOHG_01720	1.47e-91	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MHKMKOHG_01721	2.56e-175	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MHKMKOHG_01722	3.66e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MHKMKOHG_01723	1.28e-228	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MHKMKOHG_01724	9.42e-231	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MHKMKOHG_01725	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
MHKMKOHG_01726	6.3e-142	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MHKMKOHG_01727	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MHKMKOHG_01728	9.02e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MHKMKOHG_01729	5.49e-166	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MHKMKOHG_01730	4.67e-238	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHKMKOHG_01731	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MHKMKOHG_01732	2.15e-215	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MHKMKOHG_01733	5.83e-196	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
MHKMKOHG_01734	3.44e-240	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MHKMKOHG_01735	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MHKMKOHG_01736	1.01e-104	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
MHKMKOHG_01737	1.39e-141	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MHKMKOHG_01738	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MHKMKOHG_01739	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKMKOHG_01740	1.79e-84	ylxL	-	-	-	-	-	-	-
MHKMKOHG_01741	1.74e-167	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MHKMKOHG_01742	4.66e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHKMKOHG_01743	7.09e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MHKMKOHG_01744	1.59e-117	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHKMKOHG_01745	2.49e-183	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHKMKOHG_01746	1.48e-176	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MHKMKOHG_01747	1.05e-271	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHKMKOHG_01748	4.47e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MHKMKOHG_01749	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHKMKOHG_01750	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHKMKOHG_01751	9.4e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MHKMKOHG_01752	3.32e-263	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MHKMKOHG_01753	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MHKMKOHG_01754	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MHKMKOHG_01755	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHKMKOHG_01756	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MHKMKOHG_01757	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHKMKOHG_01758	7.89e-216	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHKMKOHG_01759	1.27e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MHKMKOHG_01760	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHKMKOHG_01761	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHKMKOHG_01762	2.3e-229	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MHKMKOHG_01763	3.42e-298	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MHKMKOHG_01764	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
MHKMKOHG_01765	7.16e-201	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
MHKMKOHG_01766	6.97e-131	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MHKMKOHG_01767	1.31e-244	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHKMKOHG_01768	3.69e-278	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MHKMKOHG_01769	2.06e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHKMKOHG_01770	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHKMKOHG_01771	1.89e-167	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MHKMKOHG_01772	7.4e-41	-	-	-	S	-	-	-	YlzJ-like protein
MHKMKOHG_01773	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MHKMKOHG_01774	1.38e-166	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01775	2.27e-289	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_01776	7.8e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_01777	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
MHKMKOHG_01778	3.17e-297	albE	-	-	S	-	-	-	Peptidase M16
MHKMKOHG_01779	2.54e-304	ymfH	-	-	S	-	-	-	zinc protease
MHKMKOHG_01780	3.93e-162	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MHKMKOHG_01781	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MHKMKOHG_01782	3.66e-182	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MHKMKOHG_01783	1.94e-167	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MHKMKOHG_01784	2.75e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHKMKOHG_01785	4.45e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MHKMKOHG_01786	8.4e-237	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHKMKOHG_01787	1.49e-232	pbpX	-	-	V	-	-	-	Beta-lactamase
MHKMKOHG_01788	2.91e-308	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MHKMKOHG_01789	3.06e-195	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MHKMKOHG_01790	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MHKMKOHG_01791	1.13e-248	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MHKMKOHG_01792	1.13e-270	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHKMKOHG_01793	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHKMKOHG_01794	2.03e-86	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MHKMKOHG_01795	3.93e-116	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MHKMKOHG_01796	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHKMKOHG_01797	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHKMKOHG_01798	3.5e-97	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
MHKMKOHG_01799	1.02e-201	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHKMKOHG_01800	6.46e-218	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
MHKMKOHG_01801	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHKMKOHG_01802	7.87e-93	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHKMKOHG_01803	1.24e-47	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
MHKMKOHG_01804	2.45e-307	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
MHKMKOHG_01805	3.82e-181	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
MHKMKOHG_01806	6.35e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
MHKMKOHG_01807	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MHKMKOHG_01808	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHKMKOHG_01809	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
MHKMKOHG_01810	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
MHKMKOHG_01811	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
MHKMKOHG_01812	3.72e-282	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHKMKOHG_01813	1.74e-92	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
MHKMKOHG_01814	6.09e-150	yoaK	-	-	S	-	-	-	Membrane
MHKMKOHG_01815	3.12e-79	ymzB	-	-	-	-	-	-	-
MHKMKOHG_01816	3.76e-316	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
MHKMKOHG_01817	1.86e-07	-	-	-	-	-	-	-	-
MHKMKOHG_01818	3.75e-152	ymaC	-	-	S	-	-	-	Replication protein
MHKMKOHG_01819	2.16e-98	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MHKMKOHG_01820	1.76e-70	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MHKMKOHG_01821	4.09e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MHKMKOHG_01823	1.51e-70	ymaF	-	-	S	-	-	-	YmaF family
MHKMKOHG_01824	3.06e-211	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHKMKOHG_01825	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MHKMKOHG_01826	1.12e-54	-	-	-	-	-	-	-	-
MHKMKOHG_01827	9.42e-29	ymzA	-	-	-	-	-	-	-
MHKMKOHG_01828	4.43e-77	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MHKMKOHG_01829	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHKMKOHG_01830	5.94e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHKMKOHG_01831	6.33e-132	ymaB	-	-	S	-	-	-	MutT family
MHKMKOHG_01832	9.5e-136	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MHKMKOHG_01833	7.38e-225	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MHKMKOHG_01834	3.51e-291	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHKMKOHG_01835	1.87e-307	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MHKMKOHG_01836	6.73e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
MHKMKOHG_01837	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MHKMKOHG_01838	2.32e-151	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MHKMKOHG_01839	1.79e-270	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHKMKOHG_01840	3.42e-313	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MHKMKOHG_01841	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MHKMKOHG_01842	3.05e-263	xylR	-	-	GK	-	-	-	ROK family
MHKMKOHG_01843	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MHKMKOHG_01844	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MHKMKOHG_01845	1.09e-150	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
MHKMKOHG_01846	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
MHKMKOHG_01849	1.6e-155	yobV	-	-	K	-	-	-	WYL domain
MHKMKOHG_01850	2.77e-89	dinB	-	-	S	-	-	-	DinB family
MHKMKOHG_01851	3.51e-227	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MHKMKOHG_01853	6.69e-52	-	-	-	-	-	-	-	-
MHKMKOHG_01854	2.04e-10	-	-	-	-	-	-	-	-
MHKMKOHG_01855	8.3e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
MHKMKOHG_01856	1.69e-13	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MHKMKOHG_01857	3.47e-166	yoaP	-	-	K	-	-	-	YoaP-like
MHKMKOHG_01858	5.4e-118	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHKMKOHG_01860	7.66e-48	-	-	-	-	-	-	-	-
MHKMKOHG_01862	2.39e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
MHKMKOHG_01863	1.15e-239	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKMKOHG_01864	7.85e-151	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
MHKMKOHG_01865	9.32e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MHKMKOHG_01866	1.97e-119	yvgO	-	-	-	-	-	-	-
MHKMKOHG_01868	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
MHKMKOHG_01869	1.33e-43	-	-	-	S	-	-	-	TM2 domain
MHKMKOHG_01870	9.69e-99	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
MHKMKOHG_01871	5.34e-164	yndL	-	-	S	-	-	-	Replication protein
MHKMKOHG_01872	4.12e-10	-	-	-	-	-	-	-	-
MHKMKOHG_01873	6.02e-183	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
MHKMKOHG_01874	7.14e-83	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MHKMKOHG_01877	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHKMKOHG_01878	5.61e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MHKMKOHG_01879	2.04e-142	yneB	-	-	L	-	-	-	resolvase
MHKMKOHG_01880	2.72e-42	ynzC	-	-	S	-	-	-	UPF0291 protein
MHKMKOHG_01881	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHKMKOHG_01882	9.97e-103	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MHKMKOHG_01883	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MHKMKOHG_01884	8.06e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MHKMKOHG_01885	2.52e-98	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MHKMKOHG_01886	4.11e-75	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MHKMKOHG_01887	7.59e-97	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MHKMKOHG_01888	4.28e-92	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MHKMKOHG_01889	4.56e-78	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
MHKMKOHG_01890	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
MHKMKOHG_01891	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
MHKMKOHG_01892	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHKMKOHG_01893	4.36e-114	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MHKMKOHG_01894	2.66e-09	-	-	-	S	-	-	-	Fur-regulated basic protein B
MHKMKOHG_01896	1e-43	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
MHKMKOHG_01897	8.11e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MHKMKOHG_01898	5.95e-65	yneQ	-	-	-	-	-	-	-
MHKMKOHG_01899	3.27e-58	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MHKMKOHG_01900	7.46e-120	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHKMKOHG_01901	1.41e-89	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MHKMKOHG_01902	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHKMKOHG_01903	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHKMKOHG_01904	2.21e-19	-	-	-	-	-	-	-	-
MHKMKOHG_01905	1.23e-61	ynfC	-	-	-	-	-	-	-
MHKMKOHG_01906	1.76e-316	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
MHKMKOHG_01907	2.54e-174	yndG	-	-	S	-	-	-	DoxX-like family
MHKMKOHG_01908	8.9e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
MHKMKOHG_01909	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
MHKMKOHG_01910	2.03e-67	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
MHKMKOHG_01911	2.57e-284	-	-	-	T	-	-	-	Histidine kinase
MHKMKOHG_01912	1.84e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MHKMKOHG_01913	4.93e-304	-	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
MHKMKOHG_01914	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MHKMKOHG_01915	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_01916	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_01917	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_01918	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_01919	1.1e-261	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHKMKOHG_01920	5.13e-156	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MHKMKOHG_01921	7.15e-44	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHKMKOHG_01922	3.15e-54	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHKMKOHG_01923	3.3e-145	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHKMKOHG_01924	1.08e-207	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
MHKMKOHG_01925	1.26e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MHKMKOHG_01926	6.05e-157	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MHKMKOHG_01927	2.13e-118	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHKMKOHG_01928	2.14e-87	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MHKMKOHG_01929	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MHKMKOHG_01930	3.49e-172	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MHKMKOHG_01931	6.91e-87	yngA	-	-	S	-	-	-	membrane
MHKMKOHG_01932	5e-197	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MHKMKOHG_01933	3.08e-134	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
MHKMKOHG_01934	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHKMKOHG_01935	5.13e-171	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MHKMKOHG_01936	9.17e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MHKMKOHG_01937	2.28e-40	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MHKMKOHG_01938	3.22e-304	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MHKMKOHG_01939	6.93e-312	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKMKOHG_01940	1.97e-41	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKMKOHG_01941	6.97e-264	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MHKMKOHG_01942	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MHKMKOHG_01943	9.31e-83	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MHKMKOHG_01944	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
MHKMKOHG_01945	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_01946	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MHKMKOHG_01947	2.48e-226	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MHKMKOHG_01948	7.94e-307	yoeA	-	-	V	-	-	-	MATE efflux family protein
MHKMKOHG_01949	3.39e-121	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
MHKMKOHG_01950	1.57e-234	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
MHKMKOHG_01951	1.57e-51	-	-	-	-	-	-	-	-
MHKMKOHG_01952	1.04e-43	-	-	-	N	-	-	-	Kelch motif
MHKMKOHG_01953	4.38e-22	-	-	-	L	-	-	-	phage terminase small subunit
MHKMKOHG_01954	1.37e-19	-	-	-	S	-	-	-	Phage terminase, small subunit
MHKMKOHG_01958	2.01e-09	-	-	-	L	-	-	-	Phage integrase family
MHKMKOHG_01959	2.62e-23	-	-	-	L	-	-	-	Phage integrase family
MHKMKOHG_01961	7.69e-123	-	-	-	L	-	-	-	Integrase
MHKMKOHG_01962	7.83e-46	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MHKMKOHG_01963	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MHKMKOHG_01964	1.1e-245	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
MHKMKOHG_01965	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
MHKMKOHG_01966	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHKMKOHG_01967	4.94e-188	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01968	3.11e-224	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MHKMKOHG_01969	9.23e-59	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MHKMKOHG_01970	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MHKMKOHG_01971	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MHKMKOHG_01972	4.67e-202	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_01973	2.89e-252	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHKMKOHG_01974	1.73e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHKMKOHG_01975	6.69e-81	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MHKMKOHG_01976	4.03e-156	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKMKOHG_01977	3.4e-47	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHKMKOHG_01978	1.2e-147	yoxB	-	-	-	-	-	-	-
MHKMKOHG_01979	2.9e-262	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MHKMKOHG_01980	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
MHKMKOHG_01981	2.4e-237	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHKMKOHG_01982	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHKMKOHG_01983	5.17e-35	yoaF	-	-	-	-	-	-	-
MHKMKOHG_01985	8.67e-124	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_01986	9.19e-40	-	-	-	-	-	-	-	-
MHKMKOHG_01988	5.01e-69	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
MHKMKOHG_01989	8.89e-156	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MHKMKOHG_01990	1.68e-109	yobS	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_01991	5.54e-156	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHKMKOHG_01992	7.49e-117	yobW	-	-	-	-	-	-	-
MHKMKOHG_01993	4.46e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MHKMKOHG_01994	1.34e-154	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MHKMKOHG_01995	5.42e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MHKMKOHG_01996	3.47e-172	-	-	-	J	-	-	-	Protein required for attachment to host cells
MHKMKOHG_01997	3.63e-120	yocC	-	-	-	-	-	-	-
MHKMKOHG_01998	2.94e-235	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
MHKMKOHG_02000	6.61e-157	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
MHKMKOHG_02001	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHKMKOHG_02003	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHKMKOHG_02004	6.39e-79	yocK	-	-	T	-	-	-	general stress protein
MHKMKOHG_02006	1.65e-11	yocN	-	-	-	-	-	-	-
MHKMKOHG_02007	2.21e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MHKMKOHG_02008	1.13e-58	yozN	-	-	-	-	-	-	-
MHKMKOHG_02009	1.83e-49	yocN	-	-	-	-	-	-	-
MHKMKOHG_02010	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
MHKMKOHG_02012	4.69e-43	yozC	-	-	-	-	-	-	-
MHKMKOHG_02013	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHKMKOHG_02014	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
MHKMKOHG_02015	5.12e-207	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MHKMKOHG_02016	7.69e-294	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MHKMKOHG_02017	7.41e-210	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MHKMKOHG_02018	1.37e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MHKMKOHG_02019	1.85e-256	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MHKMKOHG_02020	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MHKMKOHG_02021	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
MHKMKOHG_02022	9.9e-208	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
MHKMKOHG_02023	2.17e-134	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MHKMKOHG_02024	4.81e-276	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MHKMKOHG_02025	4.85e-278	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MHKMKOHG_02026	3.97e-136	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHKMKOHG_02028	5.03e-296	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
MHKMKOHG_02029	7.28e-186	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHKMKOHG_02030	2.61e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MHKMKOHG_02031	4.69e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MHKMKOHG_02032	3.66e-31	-	-	-	-	-	-	-	-
MHKMKOHG_02033	2.39e-200	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MHKMKOHG_02034	1.83e-101	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
MHKMKOHG_02036	9.37e-83	iolK	-	-	S	-	-	-	tautomerase
MHKMKOHG_02037	2.25e-68	yodB	-	-	K	-	-	-	transcriptional
MHKMKOHG_02038	3.7e-136	yodC	-	-	C	-	-	-	nitroreductase
MHKMKOHG_02039	4.7e-138	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MHKMKOHG_02040	3.74e-213	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MHKMKOHG_02041	1.14e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
MHKMKOHG_02042	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHKMKOHG_02043	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
MHKMKOHG_02044	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHKMKOHG_02045	3.79e-164	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_02046	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MHKMKOHG_02047	3.36e-154	yodH	-	-	Q	-	-	-	Methyltransferase
MHKMKOHG_02048	2.3e-30	yodI	-	-	-	-	-	-	-
MHKMKOHG_02049	1.5e-190	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MHKMKOHG_02050	4.29e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MHKMKOHG_02052	2.34e-72	yodL	-	-	S	-	-	-	YodL-like
MHKMKOHG_02053	1.39e-129	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MHKMKOHG_02054	1.97e-33	yozD	-	-	S	-	-	-	YozD-like protein
MHKMKOHG_02056	1.18e-155	yodN	-	-	-	-	-	-	-
MHKMKOHG_02057	6.19e-67	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKMKOHG_02058	2.87e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MHKMKOHG_02059	6.45e-59	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
MHKMKOHG_02060	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
MHKMKOHG_02061	1.61e-178	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
MHKMKOHG_02062	9.6e-316	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MHKMKOHG_02063	1.74e-155	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MHKMKOHG_02064	1.49e-155	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MHKMKOHG_02065	5.06e-298	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHKMKOHG_02067	2.78e-80	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
MHKMKOHG_02069	9.32e-175	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
MHKMKOHG_02070	4.12e-289	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
MHKMKOHG_02071	8.16e-54	cgeC	-	-	-	ko:K06321	-	ko00000	-
MHKMKOHG_02072	9.24e-83	cgeA	-	-	-	ko:K06319	-	ko00000	-
MHKMKOHG_02073	2.62e-214	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
MHKMKOHG_02074	1e-269	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
MHKMKOHG_02075	5.78e-91	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MHKMKOHG_02078	2.09e-151	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	FMN-dependent dehydrogenase
MHKMKOHG_02080	6.05e-22	-	-	-	S	-	-	-	Regulatory protein YrvL
MHKMKOHG_02081	1.94e-262	yokA	-	-	L	-	-	-	Recombinase
MHKMKOHG_02082	3.03e-128	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MHKMKOHG_02083	2.47e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MHKMKOHG_02084	7.78e-130	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHKMKOHG_02085	3.91e-88	ypoP	-	-	K	-	-	-	transcriptional
MHKMKOHG_02086	2.1e-121	ypmS	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_02087	1.04e-166	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MHKMKOHG_02088	2.24e-131	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MHKMKOHG_02089	3.66e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
MHKMKOHG_02090	9.19e-304	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHKMKOHG_02091	2.28e-209	yplP	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_02092	7.14e-141	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MHKMKOHG_02093	3.29e-139	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MHKMKOHG_02094	3.8e-111	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHKMKOHG_02095	3.6e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHKMKOHG_02096	4.91e-143	ypjP	-	-	S	-	-	-	YpjP-like protein
MHKMKOHG_02097	4.56e-168	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
MHKMKOHG_02098	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MHKMKOHG_02099	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MHKMKOHG_02100	2.44e-198	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MHKMKOHG_02101	8.73e-117	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MHKMKOHG_02102	5.15e-109	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MHKMKOHG_02104	1.28e-224	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHKMKOHG_02105	2.37e-271	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MHKMKOHG_02106	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
MHKMKOHG_02107	4.27e-16	degR	-	-	-	-	-	-	-
MHKMKOHG_02108	5.37e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MHKMKOHG_02109	6.37e-38	ypeQ	-	-	S	-	-	-	Zinc-finger
MHKMKOHG_02110	7.41e-153	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
MHKMKOHG_02111	3.96e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MHKMKOHG_02112	2.03e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
MHKMKOHG_02114	2.07e-204	ypcP	-	-	L	-	-	-	5'3' exonuclease
MHKMKOHG_02115	2.44e-10	-	-	-	-	-	-	-	-
MHKMKOHG_02116	3e-45	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
MHKMKOHG_02117	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MHKMKOHG_02118	3.19e-111	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MHKMKOHG_02119	3.27e-255	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MHKMKOHG_02120	2.82e-133	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MHKMKOHG_02121	3.4e-61	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
MHKMKOHG_02122	3.44e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MHKMKOHG_02123	1.26e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
MHKMKOHG_02124	2.3e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
MHKMKOHG_02125	4.16e-122	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHKMKOHG_02126	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MHKMKOHG_02127	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
MHKMKOHG_02129	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
MHKMKOHG_02130	2.08e-271	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MHKMKOHG_02131	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHKMKOHG_02132	3.67e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MHKMKOHG_02133	8.12e-36	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
MHKMKOHG_02135	2.01e-286	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MHKMKOHG_02136	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MHKMKOHG_02137	2.85e-114	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MHKMKOHG_02138	1.7e-82	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MHKMKOHG_02139	1.95e-70	yppG	-	-	S	-	-	-	YppG-like protein
MHKMKOHG_02143	0.00077	-	-	-	-	ko:K06430	-	ko00000	-
MHKMKOHG_02144	4.29e-225	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MHKMKOHG_02145	8.49e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHKMKOHG_02146	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MHKMKOHG_02147	2.66e-112	ypoC	-	-	-	-	-	-	-
MHKMKOHG_02148	1.4e-155	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHKMKOHG_02149	8.05e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MHKMKOHG_02150	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MHKMKOHG_02151	1.91e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MHKMKOHG_02152	1.36e-95	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_02153	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MHKMKOHG_02154	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MHKMKOHG_02155	1.63e-82	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MHKMKOHG_02156	4.82e-194	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MHKMKOHG_02157	2.31e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MHKMKOHG_02158	1.43e-226	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHKMKOHG_02159	9.21e-268	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHKMKOHG_02160	7.01e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MHKMKOHG_02161	3.8e-162	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MHKMKOHG_02162	3.58e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MHKMKOHG_02163	9.38e-187	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHKMKOHG_02164	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MHKMKOHG_02165	8.34e-197	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHKMKOHG_02166	1.59e-286	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MHKMKOHG_02167	7.66e-178	ypjB	-	-	S	-	-	-	sporulation protein
MHKMKOHG_02168	4.31e-126	ypjA	-	-	S	-	-	-	membrane
MHKMKOHG_02169	9.48e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MHKMKOHG_02170	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MHKMKOHG_02171	2.27e-124	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MHKMKOHG_02172	2.97e-95	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MHKMKOHG_02173	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MHKMKOHG_02174	3.12e-291	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MHKMKOHG_02175	9.3e-291	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHKMKOHG_02176	5.43e-255	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MHKMKOHG_02177	2.67e-251	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHKMKOHG_02178	4.39e-175	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHKMKOHG_02179	3.74e-285	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHKMKOHG_02180	2.99e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
MHKMKOHG_02181	1.99e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MHKMKOHG_02182	2.68e-201	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHKMKOHG_02183	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHKMKOHG_02184	4.68e-76	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MHKMKOHG_02185	1.88e-252	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHKMKOHG_02186	9.34e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHKMKOHG_02187	3.26e-177	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MHKMKOHG_02188	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MHKMKOHG_02189	6.56e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHKMKOHG_02190	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHKMKOHG_02191	2.68e-175	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MHKMKOHG_02192	7.29e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MHKMKOHG_02193	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MHKMKOHG_02194	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHKMKOHG_02195	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MHKMKOHG_02197	7.08e-166	yphF	-	-	-	-	-	-	-
MHKMKOHG_02198	1.13e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MHKMKOHG_02199	6.44e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MHKMKOHG_02200	2.86e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MHKMKOHG_02201	6.38e-129	yphA	-	-	-	-	-	-	-
MHKMKOHG_02202	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
MHKMKOHG_02203	2.88e-229	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHKMKOHG_02204	3.17e-261	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MHKMKOHG_02205	6.49e-143	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MHKMKOHG_02206	1.12e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
MHKMKOHG_02207	1.15e-72	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
MHKMKOHG_02208	1.1e-311	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MHKMKOHG_02209	2.15e-203	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MHKMKOHG_02210	1.84e-155	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MHKMKOHG_02211	4e-234	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MHKMKOHG_02212	7.37e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MHKMKOHG_02213	7.9e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MHKMKOHG_02214	5.62e-181	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MHKMKOHG_02215	3.73e-109	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
MHKMKOHG_02216	1.78e-109	ypbE	-	-	M	-	-	-	Lysin motif
MHKMKOHG_02217	1.57e-124	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MHKMKOHG_02218	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHKMKOHG_02219	1.35e-240	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MHKMKOHG_02220	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MHKMKOHG_02221	3.59e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHKMKOHG_02222	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHKMKOHG_02223	1.71e-218	rsiX	-	-	-	-	-	-	-
MHKMKOHG_02224	8.86e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MHKMKOHG_02225	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_02226	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_02227	3.09e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MHKMKOHG_02228	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MHKMKOHG_02229	1.45e-126	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHKMKOHG_02230	1.74e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MHKMKOHG_02231	7.39e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MHKMKOHG_02232	2.08e-132	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MHKMKOHG_02233	1.36e-267	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MHKMKOHG_02234	2.3e-104	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
MHKMKOHG_02235	1.3e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHKMKOHG_02236	3.47e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHKMKOHG_02238	1.39e-112	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MHKMKOHG_02239	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHKMKOHG_02240	8.08e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHKMKOHG_02241	4.07e-288	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MHKMKOHG_02242	2.57e-140	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MHKMKOHG_02243	1.24e-257	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHKMKOHG_02244	7.86e-68	ypuD	-	-	-	-	-	-	-
MHKMKOHG_02245	2.37e-124	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MHKMKOHG_02246	6.23e-102	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
MHKMKOHG_02247	1.18e-103	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHKMKOHG_02248	1.17e-194	ypuA	-	-	S	-	-	-	Secreted protein
MHKMKOHG_02249	2.84e-316	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHKMKOHG_02250	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MHKMKOHG_02251	2.95e-139	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MHKMKOHG_02252	3.57e-74	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MHKMKOHG_02253	9.17e-241	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MHKMKOHG_02254	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MHKMKOHG_02255	7.71e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
MHKMKOHG_02256	9.1e-141	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
MHKMKOHG_02257	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKMKOHG_02258	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MHKMKOHG_02259	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MHKMKOHG_02260	6.51e-269	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MHKMKOHG_02261	2.05e-188	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MHKMKOHG_02262	1.31e-289	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHKMKOHG_02263	4.38e-211	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MHKMKOHG_02264	5.51e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MHKMKOHG_02265	3.08e-102	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MHKMKOHG_02266	7.12e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MHKMKOHG_02267	2.87e-43	yqkK	-	-	-	-	-	-	-
MHKMKOHG_02268	5.05e-33	-	-	-	-	-	-	-	-
MHKMKOHG_02269	3.1e-305	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MHKMKOHG_02270	7.17e-313	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MHKMKOHG_02271	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MHKMKOHG_02272	4.88e-236	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
MHKMKOHG_02273	2.32e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_02274	2.47e-272	yqxK	-	-	L	-	-	-	DNA helicase
MHKMKOHG_02275	1.42e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MHKMKOHG_02276	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
MHKMKOHG_02277	5.74e-212	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MHKMKOHG_02278	3.06e-15	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
MHKMKOHG_02279	4.33e-212	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MHKMKOHG_02280	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
MHKMKOHG_02281	1.74e-76	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
MHKMKOHG_02282	8.2e-214	yqkA	-	-	K	-	-	-	GrpB protein
MHKMKOHG_02284	2.22e-112	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
MHKMKOHG_02285	6.1e-295	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHKMKOHG_02286	3.08e-74	-	-	-	S	-	-	-	YolD-like protein
MHKMKOHG_02288	5.73e-206	yueF	-	-	S	-	-	-	transporter activity
MHKMKOHG_02290	3.01e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MHKMKOHG_02291	5.94e-300	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MHKMKOHG_02292	8.58e-174	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKMKOHG_02293	2.24e-213	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHKMKOHG_02294	2.17e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHKMKOHG_02295	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
MHKMKOHG_02296	5.05e-121	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MHKMKOHG_02297	9.48e-204	-	-	-	K	-	-	-	LysR substrate binding domain
MHKMKOHG_02298	2.42e-61	-	-	-	S	-	-	-	GlpM protein
MHKMKOHG_02299	1.04e-246	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MHKMKOHG_02300	5.52e-176	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MHKMKOHG_02301	4.44e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MHKMKOHG_02302	8.52e-215	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHKMKOHG_02303	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHKMKOHG_02304	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHKMKOHG_02305	5.48e-294	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHKMKOHG_02306	1.36e-36	yqzJ	-	-	-	-	-	-	-
MHKMKOHG_02307	6.56e-188	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHKMKOHG_02308	5.04e-257	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MHKMKOHG_02309	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MHKMKOHG_02310	5.21e-93	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MHKMKOHG_02312	6.62e-117	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_02313	6.23e-217	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MHKMKOHG_02314	2.77e-161	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHKMKOHG_02315	6.03e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MHKMKOHG_02316	3.77e-171	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MHKMKOHG_02317	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MHKMKOHG_02318	7.9e-215	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MHKMKOHG_02319	1.56e-264	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHKMKOHG_02320	1.15e-233	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MHKMKOHG_02321	4.18e-217	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MHKMKOHG_02322	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MHKMKOHG_02323	1.11e-259	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
MHKMKOHG_02324	6.15e-259	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MHKMKOHG_02325	6.51e-193	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
MHKMKOHG_02326	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MHKMKOHG_02327	7.32e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MHKMKOHG_02328	2.12e-200	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MHKMKOHG_02329	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MHKMKOHG_02330	1.63e-259	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MHKMKOHG_02331	1.62e-256	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MHKMKOHG_02332	9.24e-186	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MHKMKOHG_02333	8.51e-267	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MHKMKOHG_02334	2.98e-163	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MHKMKOHG_02335	1.86e-125	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
MHKMKOHG_02337	2.41e-117	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MHKMKOHG_02338	3.85e-144	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
MHKMKOHG_02340	4.72e-265	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MHKMKOHG_02343	3.04e-260	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHKMKOHG_02345	2.05e-185	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MHKMKOHG_02346	1.35e-298	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MHKMKOHG_02347	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MHKMKOHG_02348	1.03e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MHKMKOHG_02349	2.69e-193	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MHKMKOHG_02350	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHKMKOHG_02351	4.32e-202	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MHKMKOHG_02352	4.44e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHKMKOHG_02353	7.61e-308	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHKMKOHG_02354	2.51e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHKMKOHG_02355	2.58e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHKMKOHG_02356	2.25e-86	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_02357	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MHKMKOHG_02358	2.59e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHKMKOHG_02359	1.88e-86	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MHKMKOHG_02360	1.3e-145	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MHKMKOHG_02361	1.74e-129	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MHKMKOHG_02362	1.05e-260	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MHKMKOHG_02363	5.28e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MHKMKOHG_02364	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MHKMKOHG_02365	2.71e-109	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MHKMKOHG_02366	2.26e-214	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MHKMKOHG_02367	1.16e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MHKMKOHG_02368	9.69e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHKMKOHG_02369	2.75e-245	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MHKMKOHG_02370	3.02e-113	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MHKMKOHG_02371	3.89e-216	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
MHKMKOHG_02372	8.59e-80	yqhP	-	-	-	-	-	-	-
MHKMKOHG_02373	1.25e-203	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MHKMKOHG_02374	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MHKMKOHG_02375	1.78e-201	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MHKMKOHG_02376	1.35e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MHKMKOHG_02377	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHKMKOHG_02378	5.87e-311	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MHKMKOHG_02379	1.05e-251	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MHKMKOHG_02380	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHKMKOHG_02381	1.02e-193	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MHKMKOHG_02382	1.3e-29	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
MHKMKOHG_02383	2.27e-71	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
MHKMKOHG_02384	8.28e-178	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
MHKMKOHG_02385	1.91e-95	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MHKMKOHG_02386	7.32e-144	yqxM	-	-	-	ko:K19433	-	ko00000	-
MHKMKOHG_02387	3.28e-69	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
MHKMKOHG_02388	1.65e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
MHKMKOHG_02389	7.78e-71	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
MHKMKOHG_02390	1e-63	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
MHKMKOHG_02391	3.85e-27	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
MHKMKOHG_02392	4.41e-91	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
MHKMKOHG_02393	8.07e-54	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MHKMKOHG_02394	6.75e-226	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MHKMKOHG_02395	6.83e-252	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MHKMKOHG_02396	1.1e-230	yqxL	-	-	P	-	-	-	Mg2 transporter protein
MHKMKOHG_02397	1.1e-296	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHKMKOHG_02398	7.51e-177	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MHKMKOHG_02400	2.15e-82	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
MHKMKOHG_02401	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MHKMKOHG_02402	2e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MHKMKOHG_02403	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
MHKMKOHG_02404	3.5e-64	dglA	-	-	S	-	-	-	Thiamine-binding protein
MHKMKOHG_02405	1.34e-240	yqgU	-	-	-	-	-	-	-
MHKMKOHG_02406	2.3e-257	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
MHKMKOHG_02407	1.18e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MHKMKOHG_02408	1.87e-37	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
MHKMKOHG_02409	3.67e-269	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MHKMKOHG_02410	5.38e-11	yqgO	-	-	-	-	-	-	-
MHKMKOHG_02411	8.53e-117	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHKMKOHG_02412	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MHKMKOHG_02413	3.42e-68	yqzD	-	-	-	-	-	-	-
MHKMKOHG_02414	1.97e-96	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHKMKOHG_02415	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHKMKOHG_02416	8.56e-179	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHKMKOHG_02417	4.62e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MHKMKOHG_02418	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MHKMKOHG_02419	1.06e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MHKMKOHG_02420	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
MHKMKOHG_02421	5.94e-283	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MHKMKOHG_02422	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MHKMKOHG_02423	7.59e-97	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MHKMKOHG_02424	8.5e-165	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
MHKMKOHG_02425	5.95e-59	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
MHKMKOHG_02426	2.3e-255	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHKMKOHG_02427	3.9e-79	yqfX	-	-	S	-	-	-	membrane
MHKMKOHG_02428	3.23e-139	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MHKMKOHG_02429	2.63e-99	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
MHKMKOHG_02430	2.47e-195	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHKMKOHG_02431	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
MHKMKOHG_02432	1.85e-208	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHKMKOHG_02433	2.37e-307	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHKMKOHG_02434	7.12e-57	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MHKMKOHG_02435	4.12e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHKMKOHG_02436	4.21e-266	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHKMKOHG_02437	8.17e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MHKMKOHG_02438	7.67e-80	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MHKMKOHG_02439	8e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHKMKOHG_02440	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHKMKOHG_02441	2.09e-91	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MHKMKOHG_02442	1.75e-188	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHKMKOHG_02443	3.41e-144	ccpN	-	-	K	-	-	-	CBS domain
MHKMKOHG_02444	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MHKMKOHG_02445	2.47e-221	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MHKMKOHG_02446	3.28e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MHKMKOHG_02447	6e-24	-	-	-	S	-	-	-	YqzL-like protein
MHKMKOHG_02448	2.01e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHKMKOHG_02449	2.73e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHKMKOHG_02450	7.21e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MHKMKOHG_02451	2.91e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHKMKOHG_02452	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MHKMKOHG_02453	2.37e-222	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MHKMKOHG_02454	1.68e-274	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MHKMKOHG_02455	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MHKMKOHG_02456	1.28e-48	yqfB	-	-	-	-	-	-	-
MHKMKOHG_02457	1.22e-186	yqfA	-	-	S	-	-	-	UPF0365 protein
MHKMKOHG_02458	1.3e-286	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MHKMKOHG_02459	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MHKMKOHG_02460	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MHKMKOHG_02461	2.83e-194	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MHKMKOHG_02462	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MHKMKOHG_02463	3.96e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHKMKOHG_02464	3.65e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MHKMKOHG_02465	4.72e-264	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHKMKOHG_02466	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MHKMKOHG_02467	1.4e-104	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHKMKOHG_02468	1.11e-237	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHKMKOHG_02469	3.34e-266	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MHKMKOHG_02470	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHKMKOHG_02471	2.88e-69	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
MHKMKOHG_02472	4.32e-278	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MHKMKOHG_02473	1.33e-255	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MHKMKOHG_02474	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MHKMKOHG_02475	2.37e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MHKMKOHG_02476	7.73e-22	-	-	-	S	-	-	-	YqzM-like protein
MHKMKOHG_02477	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MHKMKOHG_02478	2.11e-133	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MHKMKOHG_02479	2.18e-122	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MHKMKOHG_02480	2.47e-185	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHKMKOHG_02481	7.42e-173	yqeM	-	-	Q	-	-	-	Methyltransferase
MHKMKOHG_02482	3.83e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHKMKOHG_02483	7.98e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MHKMKOHG_02484	2.56e-134	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHKMKOHG_02485	8.62e-59	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MHKMKOHG_02486	5.24e-195	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHKMKOHG_02487	1.08e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MHKMKOHG_02488	7.28e-122	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MHKMKOHG_02490	3.83e-174	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MHKMKOHG_02491	3.4e-173	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MHKMKOHG_02492	1.27e-139	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MHKMKOHG_02493	9.76e-137	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
MHKMKOHG_02494	1.85e-257	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MHKMKOHG_02495	1.17e-158	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MHKMKOHG_02496	1.52e-203	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MHKMKOHG_02497	9.07e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MHKMKOHG_02498	1.29e-126	yqaC	-	-	F	-	-	-	adenylate kinase activity
MHKMKOHG_02499	2.77e-282	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_02500	3.48e-114	-	-	-	S	-	-	-	DinB family
MHKMKOHG_02501	1.6e-178	supH	-	-	S	-	-	-	hydrolase
MHKMKOHG_02502	9.98e-179	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MHKMKOHG_02503	9.18e-156	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MHKMKOHG_02504	4.38e-216	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MHKMKOHG_02505	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_02506	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
MHKMKOHG_02507	1.66e-215	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
MHKMKOHG_02508	5.57e-99	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHKMKOHG_02509	3.47e-206	yybE	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_02510	1.29e-263	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_02511	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
MHKMKOHG_02512	3.6e-125	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
MHKMKOHG_02513	8.92e-112	yrhH	-	-	Q	-	-	-	methyltransferase
MHKMKOHG_02514	8.27e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
MHKMKOHG_02515	2.1e-178	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
MHKMKOHG_02516	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
MHKMKOHG_02517	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
MHKMKOHG_02518	4.38e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MHKMKOHG_02519	9.51e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
MHKMKOHG_02520	2.65e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MHKMKOHG_02521	8.52e-212	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MHKMKOHG_02522	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHKMKOHG_02523	3.7e-148	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
MHKMKOHG_02524	2.53e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
MHKMKOHG_02525	6.53e-120	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MHKMKOHG_02526	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
MHKMKOHG_02527	5.41e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHKMKOHG_02528	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MHKMKOHG_02529	1.8e-310	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
MHKMKOHG_02530	1.22e-219	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
MHKMKOHG_02531	5.63e-145	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MHKMKOHG_02532	1.71e-244	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHKMKOHG_02533	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MHKMKOHG_02534	4.51e-92	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHKMKOHG_02535	1.29e-54	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MHKMKOHG_02536	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHKMKOHG_02537	4.87e-223	yrrI	-	-	S	-	-	-	AI-2E family transporter
MHKMKOHG_02538	1.43e-164	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHKMKOHG_02539	2.76e-183	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MHKMKOHG_02540	1.13e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHKMKOHG_02541	4.21e-136	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHKMKOHG_02542	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
MHKMKOHG_02543	8.4e-42	yrzR	-	-	-	-	-	-	-
MHKMKOHG_02544	7.39e-100	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_02545	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHKMKOHG_02546	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MHKMKOHG_02547	1.39e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHKMKOHG_02548	1.12e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MHKMKOHG_02549	3.74e-83	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_02550	2.07e-300	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MHKMKOHG_02551	6.85e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MHKMKOHG_02552	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHKMKOHG_02553	2.64e-304	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MHKMKOHG_02556	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MHKMKOHG_02557	4.75e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHKMKOHG_02558	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHKMKOHG_02559	1.71e-116	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHKMKOHG_02560	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MHKMKOHG_02561	1.24e-59	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MHKMKOHG_02562	3.2e-105	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
MHKMKOHG_02563	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MHKMKOHG_02564	2.26e-64	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MHKMKOHG_02565	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKMKOHG_02566	1.16e-133	yrbG	-	-	S	-	-	-	membrane
MHKMKOHG_02567	7.46e-80	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MHKMKOHG_02568	1.03e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MHKMKOHG_02569	6.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHKMKOHG_02570	2.26e-243	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHKMKOHG_02571	2.39e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MHKMKOHG_02572	8.05e-233	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHKMKOHG_02573	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHKMKOHG_02574	1.16e-118	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MHKMKOHG_02576	1.26e-60	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MHKMKOHG_02577	1.25e-218	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MHKMKOHG_02578	1.71e-262	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MHKMKOHG_02579	6.44e-181	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MHKMKOHG_02580	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MHKMKOHG_02581	1.36e-267	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MHKMKOHG_02582	1.05e-115	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MHKMKOHG_02583	1.51e-201	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MHKMKOHG_02584	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MHKMKOHG_02585	1.95e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHKMKOHG_02586	8.24e-137	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MHKMKOHG_02587	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MHKMKOHG_02588	5.56e-72	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MHKMKOHG_02589	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MHKMKOHG_02590	1.29e-199	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MHKMKOHG_02591	1.53e-176	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MHKMKOHG_02592	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MHKMKOHG_02593	1.61e-153	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHKMKOHG_02594	4.64e-106	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MHKMKOHG_02595	2.51e-201	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MHKMKOHG_02596	2.91e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MHKMKOHG_02597	1.19e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MHKMKOHG_02598	4.58e-128	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MHKMKOHG_02599	4.35e-193	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
MHKMKOHG_02600	1.91e-157	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MHKMKOHG_02601	5.88e-295	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MHKMKOHG_02602	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHKMKOHG_02603	3.61e-34	-	-	-	-	-	-	-	-
MHKMKOHG_02604	1.35e-235	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MHKMKOHG_02605	1.29e-225	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MHKMKOHG_02606	2.87e-306	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MHKMKOHG_02607	1.7e-234	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MHKMKOHG_02608	1.17e-174	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MHKMKOHG_02609	1.73e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MHKMKOHG_02610	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MHKMKOHG_02611	2.79e-311	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MHKMKOHG_02612	1.8e-110	ysxD	-	-	-	-	-	-	-
MHKMKOHG_02613	8.88e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MHKMKOHG_02614	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MHKMKOHG_02615	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MHKMKOHG_02616	2.7e-295	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHKMKOHG_02617	2.96e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHKMKOHG_02618	6.44e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
MHKMKOHG_02619	3.62e-148	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHKMKOHG_02620	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHKMKOHG_02621	2.66e-249	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHKMKOHG_02622	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHKMKOHG_02623	6.75e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHKMKOHG_02624	1.45e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MHKMKOHG_02625	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MHKMKOHG_02630	5.1e-113	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MHKMKOHG_02631	1.25e-128	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHKMKOHG_02632	1.18e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MHKMKOHG_02633	1.05e-253	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MHKMKOHG_02634	1.29e-193	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MHKMKOHG_02635	7.32e-95	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MHKMKOHG_02636	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_02637	8.26e-96	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MHKMKOHG_02638	1.77e-188	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MHKMKOHG_02639	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MHKMKOHG_02640	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MHKMKOHG_02641	2.86e-102	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MHKMKOHG_02642	2.17e-268	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MHKMKOHG_02643	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHKMKOHG_02644	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MHKMKOHG_02645	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MHKMKOHG_02646	1.37e-224	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MHKMKOHG_02647	5.83e-176	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MHKMKOHG_02648	1.72e-169	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MHKMKOHG_02649	1.78e-133	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_02650	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MHKMKOHG_02651	2.11e-146	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
MHKMKOHG_02652	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MHKMKOHG_02653	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHKMKOHG_02654	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MHKMKOHG_02655	2.02e-107	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MHKMKOHG_02656	4.23e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHKMKOHG_02657	2.43e-212	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHKMKOHG_02658	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHKMKOHG_02659	2.1e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHKMKOHG_02660	4.97e-168	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHKMKOHG_02661	8.83e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MHKMKOHG_02662	6.24e-246	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MHKMKOHG_02663	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
MHKMKOHG_02664	3.15e-312	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MHKMKOHG_02665	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MHKMKOHG_02666	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MHKMKOHG_02667	2.19e-187	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
MHKMKOHG_02668	5.47e-209	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MHKMKOHG_02669	1.98e-314	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
MHKMKOHG_02670	4.76e-269	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MHKMKOHG_02671	5.57e-108	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MHKMKOHG_02672	4.89e-58	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MHKMKOHG_02673	2.82e-169	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MHKMKOHG_02674	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MHKMKOHG_02675	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MHKMKOHG_02676	2.15e-235	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MHKMKOHG_02677	1.52e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MHKMKOHG_02678	4.11e-82	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MHKMKOHG_02679	7.18e-52	ysdA	-	-	S	-	-	-	Membrane
MHKMKOHG_02680	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHKMKOHG_02681	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MHKMKOHG_02682	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHKMKOHG_02683	4.22e-145	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MHKMKOHG_02684	7.85e-67	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
MHKMKOHG_02685	8.26e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MHKMKOHG_02686	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_02687	3.03e-186	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MHKMKOHG_02688	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHKMKOHG_02689	6.12e-192	ytxC	-	-	S	-	-	-	YtxC-like family
MHKMKOHG_02690	2.5e-128	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
MHKMKOHG_02691	2.64e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MHKMKOHG_02692	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MHKMKOHG_02693	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHKMKOHG_02694	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MHKMKOHG_02695	4.24e-247	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHKMKOHG_02696	7.74e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_02697	9.49e-251	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
MHKMKOHG_02698	2.83e-199	ytbE	-	-	S	-	-	-	reductase
MHKMKOHG_02699	3.52e-120	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHKMKOHG_02700	4.52e-135	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MHKMKOHG_02701	1.44e-195	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHKMKOHG_02702	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHKMKOHG_02703	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MHKMKOHG_02704	5.62e-165	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_02705	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MHKMKOHG_02706	1.26e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MHKMKOHG_02707	8.21e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MHKMKOHG_02708	1.92e-96	ytwI	-	-	S	-	-	-	membrane
MHKMKOHG_02709	8.18e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MHKMKOHG_02710	1.34e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MHKMKOHG_02711	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MHKMKOHG_02712	1.33e-228	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHKMKOHG_02713	3.28e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MHKMKOHG_02714	2.08e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHKMKOHG_02715	9.53e-284	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MHKMKOHG_02716	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MHKMKOHG_02717	1.12e-71	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MHKMKOHG_02718	2.54e-112	ytrI	-	-	-	-	-	-	-
MHKMKOHG_02719	1.17e-30	-	-	-	-	-	-	-	-
MHKMKOHG_02720	4.26e-222	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MHKMKOHG_02721	3.44e-60	ytpI	-	-	S	-	-	-	YtpI-like protein
MHKMKOHG_02722	3.87e-303	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MHKMKOHG_02723	2.31e-163	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MHKMKOHG_02724	1.33e-180	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_02726	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MHKMKOHG_02727	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHKMKOHG_02728	3.87e-113	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MHKMKOHG_02729	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHKMKOHG_02730	2.11e-225	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MHKMKOHG_02731	1.12e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHKMKOHG_02732	1.37e-99	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MHKMKOHG_02733	2.09e-146	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MHKMKOHG_02734	1.86e-103	yteJ	-	-	S	-	-	-	RDD family
MHKMKOHG_02735	3.79e-227	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MHKMKOHG_02736	5.03e-191	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHKMKOHG_02737	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
MHKMKOHG_02738	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHKMKOHG_02739	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MHKMKOHG_02740	3.05e-280	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHKMKOHG_02741	3.99e-259	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MHKMKOHG_02742	8.89e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MHKMKOHG_02743	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHKMKOHG_02744	1.61e-184	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MHKMKOHG_02745	4.48e-137	yttP	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_02746	2.38e-109	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MHKMKOHG_02747	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
MHKMKOHG_02748	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHKMKOHG_02749	1e-271	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHKMKOHG_02753	1.07e-161	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MHKMKOHG_02754	9.24e-189	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHKMKOHG_02755	3.69e-189	-	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_02756	7.21e-154	ygaZ	-	-	E	-	-	-	AzlC protein
MHKMKOHG_02757	7.23e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MHKMKOHG_02758	5.73e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHKMKOHG_02759	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MHKMKOHG_02760	3.32e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MHKMKOHG_02761	1.01e-139	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
MHKMKOHG_02762	1.99e-283	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MHKMKOHG_02763	6.98e-145	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MHKMKOHG_02764	2.47e-184	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MHKMKOHG_02765	7.72e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MHKMKOHG_02766	1.8e-248	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MHKMKOHG_02767	8.39e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MHKMKOHG_02768	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MHKMKOHG_02769	2.16e-25	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHKMKOHG_02770	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MHKMKOHG_02771	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MHKMKOHG_02772	9.89e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHKMKOHG_02773	1.1e-186	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MHKMKOHG_02774	2.23e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
MHKMKOHG_02775	5.33e-98	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MHKMKOHG_02776	2.06e-258	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MHKMKOHG_02777	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
MHKMKOHG_02778	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MHKMKOHG_02779	5.74e-204	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MHKMKOHG_02780	4.34e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHKMKOHG_02781	6.45e-59	ytzH	-	-	S	-	-	-	YtzH-like protein
MHKMKOHG_02782	1.63e-196	ytmP	-	-	M	-	-	-	Phosphotransferase
MHKMKOHG_02783	4.56e-215	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MHKMKOHG_02784	1e-198	ytlQ	-	-	-	-	-	-	-
MHKMKOHG_02785	5.85e-128	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MHKMKOHG_02786	9.95e-215	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MHKMKOHG_02787	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
MHKMKOHG_02788	3.89e-286	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MHKMKOHG_02789	2.01e-250	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
MHKMKOHG_02790	5.76e-151	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MHKMKOHG_02791	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MHKMKOHG_02792	4.25e-160	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MHKMKOHG_02793	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKMKOHG_02794	5.44e-292	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MHKMKOHG_02795	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MHKMKOHG_02796	1.22e-34	yteV	-	-	S	-	-	-	Sporulation protein Cse60
MHKMKOHG_02797	3.26e-231	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_02798	4.85e-296	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MHKMKOHG_02799	1.72e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHKMKOHG_02800	1.17e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MHKMKOHG_02801	1.01e-312	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MHKMKOHG_02802	8.6e-94	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
MHKMKOHG_02803	7.08e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
MHKMKOHG_02804	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MHKMKOHG_02805	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
MHKMKOHG_02806	1.79e-172	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MHKMKOHG_02807	1.78e-264	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MHKMKOHG_02808	1.03e-151	ywaF	-	-	S	-	-	-	Integral membrane protein
MHKMKOHG_02809	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MHKMKOHG_02810	2.57e-171	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_02811	1.57e-208	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
MHKMKOHG_02812	2.2e-158	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_02813	5.02e-258	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MHKMKOHG_02814	7.08e-160	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_02815	2.19e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
MHKMKOHG_02816	1.66e-206	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHKMKOHG_02817	8.43e-216	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHKMKOHG_02818	3.7e-201	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_02819	6.32e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MHKMKOHG_02821	1.43e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
MHKMKOHG_02822	6.73e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
MHKMKOHG_02823	4.07e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MHKMKOHG_02825	8.82e-266	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MHKMKOHG_02826	1.91e-191	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MHKMKOHG_02827	7.46e-80	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MHKMKOHG_02828	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHKMKOHG_02829	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MHKMKOHG_02830	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHKMKOHG_02831	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MHKMKOHG_02832	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
MHKMKOHG_02833	2.06e-185	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MHKMKOHG_02834	1.22e-227	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MHKMKOHG_02835	1.38e-180	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHKMKOHG_02836	9.79e-170	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MHKMKOHG_02837	5.86e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MHKMKOHG_02838	1.67e-77	ytkC	-	-	S	-	-	-	Bacteriophage holin family
MHKMKOHG_02839	3e-98	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MHKMKOHG_02841	9.99e-98	ytkA	-	-	S	-	-	-	YtkA-like
MHKMKOHG_02842	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHKMKOHG_02843	5.71e-52	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MHKMKOHG_02844	4.26e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MHKMKOHG_02845	4.14e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MHKMKOHG_02846	6.36e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MHKMKOHG_02847	1.01e-232	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MHKMKOHG_02848	3.45e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MHKMKOHG_02849	2.54e-266	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MHKMKOHG_02850	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHKMKOHG_02851	7.22e-198	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHKMKOHG_02852	2.79e-187	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MHKMKOHG_02853	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MHKMKOHG_02854	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MHKMKOHG_02855	8.57e-160	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MHKMKOHG_02856	9.33e-96	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MHKMKOHG_02878	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
MHKMKOHG_02879	4.32e-119	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MHKMKOHG_02880	1.38e-273	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MHKMKOHG_02881	1.04e-104	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MHKMKOHG_02882	4.75e-101	yuaE	-	-	S	-	-	-	DinB superfamily
MHKMKOHG_02883	1.21e-134	-	-	-	S	-	-	-	MOSC domain
MHKMKOHG_02884	9.64e-288	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MHKMKOHG_02885	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHKMKOHG_02886	4.78e-119	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MHKMKOHG_02887	4.6e-119	yuaB	-	-	-	-	-	-	-
MHKMKOHG_02888	1.97e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MHKMKOHG_02889	2.76e-186	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHKMKOHG_02890	6.52e-270	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MHKMKOHG_02891	2.3e-142	-	-	-	G	-	-	-	Cupin
MHKMKOHG_02892	6.21e-59	yjcN	-	-	-	-	-	-	-
MHKMKOHG_02895	2.15e-177	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
MHKMKOHG_02896	7.36e-20	-	-	-	-	-	-	-	-
MHKMKOHG_02898	7.33e-184	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHKMKOHG_02899	2.73e-248	yubA	-	-	S	-	-	-	transporter activity
MHKMKOHG_02900	4.84e-231	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MHKMKOHG_02901	5.71e-126	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MHKMKOHG_02902	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHKMKOHG_02903	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHKMKOHG_02904	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHKMKOHG_02905	3.66e-284	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MHKMKOHG_02906	4.12e-175	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MHKMKOHG_02907	1.82e-52	-	-	-	-	-	-	-	-
MHKMKOHG_02908	1.07e-237	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MHKMKOHG_02909	8.06e-96	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MHKMKOHG_02910	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
MHKMKOHG_02911	1.82e-293	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MHKMKOHG_02912	1.95e-149	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MHKMKOHG_02913	3.56e-22	-	-	-	-	-	-	-	-
MHKMKOHG_02914	8.53e-36	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
MHKMKOHG_02915	8.97e-227	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
MHKMKOHG_02916	4.57e-90	yugN	-	-	S	-	-	-	YugN-like family
MHKMKOHG_02917	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MHKMKOHG_02918	3.35e-125	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MHKMKOHG_02919	4e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
MHKMKOHG_02920	8.85e-288	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
MHKMKOHG_02921	3.72e-283	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MHKMKOHG_02922	1.28e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MHKMKOHG_02923	8.3e-82	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MHKMKOHG_02924	1.79e-261	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MHKMKOHG_02925	1.53e-108	alaR	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_02926	3.41e-192	yugF	-	-	I	-	-	-	Hydrolase
MHKMKOHG_02927	7.97e-51	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
MHKMKOHG_02928	4.65e-277	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MHKMKOHG_02929	1.19e-281	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_02930	1.97e-72	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MHKMKOHG_02931	7.27e-151	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
MHKMKOHG_02932	2.6e-240	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MHKMKOHG_02933	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MHKMKOHG_02934	5.95e-92	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_02935	4.19e-97	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MHKMKOHG_02936	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MHKMKOHG_02937	3.8e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MHKMKOHG_02938	3.92e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MHKMKOHG_02939	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_02940	1.68e-232	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHKMKOHG_02941	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHKMKOHG_02943	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MHKMKOHG_02944	8.6e-88	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHKMKOHG_02945	1.42e-65	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHKMKOHG_02946	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHKMKOHG_02947	2.77e-98	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHKMKOHG_02948	1.84e-50	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MHKMKOHG_02949	2.84e-77	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MHKMKOHG_02950	3.55e-77	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
MHKMKOHG_02951	3.29e-147	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHKMKOHG_02952	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_02954	2.98e-123	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
MHKMKOHG_02955	1.87e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
MHKMKOHG_02956	1.36e-63	yuzC	-	-	-	-	-	-	-
MHKMKOHG_02957	2.63e-284	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
MHKMKOHG_02958	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHKMKOHG_02959	7.41e-131	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
MHKMKOHG_02960	4.96e-86	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MHKMKOHG_02961	1.57e-50	yueH	-	-	S	-	-	-	YueH-like protein
MHKMKOHG_02962	4.3e-44	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
MHKMKOHG_02963	1.15e-232	yueF	-	-	S	-	-	-	transporter activity
MHKMKOHG_02964	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MHKMKOHG_02965	9.08e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MHKMKOHG_02966	4.06e-160	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_02967	3e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
MHKMKOHG_02968	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
MHKMKOHG_02969	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MHKMKOHG_02970	3.32e-259	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MHKMKOHG_02971	8.78e-52	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MHKMKOHG_02972	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
MHKMKOHG_02973	6.77e-288	yukF	-	-	QT	-	-	-	Transcriptional regulator
MHKMKOHG_02974	1.83e-257	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MHKMKOHG_02975	1.11e-164	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
MHKMKOHG_02976	3.6e-42	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
MHKMKOHG_02977	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_02978	1.2e-209	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
MHKMKOHG_02979	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
MHKMKOHG_02980	4.99e-273	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
MHKMKOHG_02981	2.65e-166	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKMKOHG_02982	1.05e-194	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
MHKMKOHG_02983	1.48e-151	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
MHKMKOHG_02984	4.35e-130	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
MHKMKOHG_02985	7.47e-272	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MHKMKOHG_02986	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MHKMKOHG_02987	1.18e-99	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MHKMKOHG_02988	2.23e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_02989	8.54e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
MHKMKOHG_02990	3.83e-297	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MHKMKOHG_02991	1.15e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MHKMKOHG_02993	1.29e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHKMKOHG_02994	1.42e-58	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MHKMKOHG_02995	1.21e-21	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
MHKMKOHG_02996	2.09e-167	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKMKOHG_02999	4.13e-125	res	-	-	L	-	-	-	Resolvase, N terminal domain
MHKMKOHG_03001	1.14e-236	-	-	-	KLT	-	-	-	Protein tyrosine kinase
MHKMKOHG_03002	1.2e-101	-	-	-	-	-	-	-	-
MHKMKOHG_03006	6.87e-53	-	-	-	L	-	-	-	ATP-dependent DNA helicase
MHKMKOHG_03007	1.45e-205	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MHKMKOHG_03008	4.44e-79	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MHKMKOHG_03009	8.81e-205	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHKMKOHG_03010	2.57e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHKMKOHG_03011	8e-49	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MHKMKOHG_03012	7.79e-262	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MHKMKOHG_03013	6.39e-71	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03014	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MHKMKOHG_03015	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MHKMKOHG_03016	4.48e-206	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHKMKOHG_03017	5.18e-248	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MHKMKOHG_03018	1.6e-305	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MHKMKOHG_03019	1.36e-244	yutH	-	-	S	-	-	-	Spore coat protein
MHKMKOHG_03020	1.07e-108	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MHKMKOHG_03021	1.96e-178	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHKMKOHG_03022	3e-93	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MHKMKOHG_03023	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03024	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MHKMKOHG_03025	1.26e-245	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MHKMKOHG_03026	1.53e-164	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MHKMKOHG_03027	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MHKMKOHG_03028	5.58e-182	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MHKMKOHG_03029	7.05e-215	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MHKMKOHG_03030	2.23e-73	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
MHKMKOHG_03031	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MHKMKOHG_03032	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MHKMKOHG_03033	6.3e-86	-	-	-	-	-	-	-	-
MHKMKOHG_03034	1.08e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_03035	1.04e-286	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MHKMKOHG_03036	3.3e-281	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MHKMKOHG_03037	2.74e-208	bsn	-	-	L	-	-	-	Ribonuclease
MHKMKOHG_03038	4.27e-252	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_03039	1.62e-170	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
MHKMKOHG_03040	4.19e-203	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MHKMKOHG_03041	1.19e-198	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MHKMKOHG_03042	7.16e-201	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHKMKOHG_03043	2.27e-305	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
MHKMKOHG_03044	1.06e-234	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MHKMKOHG_03045	9.63e-26	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MHKMKOHG_03047	1.36e-84	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
MHKMKOHG_03048	6.28e-251	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MHKMKOHG_03049	1.33e-54	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MHKMKOHG_03050	2.91e-93	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
MHKMKOHG_03051	5.42e-153	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MHKMKOHG_03052	3.22e-63	-	-	-	-	-	-	-	-
MHKMKOHG_03054	5.17e-88	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
MHKMKOHG_03055	2.25e-76	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
MHKMKOHG_03058	1.61e-209	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
MHKMKOHG_03059	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
MHKMKOHG_03060	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
MHKMKOHG_03061	8.01e-150	-	-	-	S	-	-	-	Phage tail protein
MHKMKOHG_03062	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
MHKMKOHG_03064	3.52e-44	-	-	-	S	-	-	-	Phage tail tube protein
MHKMKOHG_03066	1.26e-43	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MHKMKOHG_03067	1.05e-40	-	-	-	S	-	-	-	Phage head-tail joining protein
MHKMKOHG_03068	5.7e-11	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MHKMKOHG_03069	5.73e-32	-	-	-	-	-	-	-	-
MHKMKOHG_03070	2.4e-167	-	-	-	S	-	-	-	capsid protein
MHKMKOHG_03071	8.38e-96	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
MHKMKOHG_03072	3.63e-221	-	-	-	S	-	-	-	portal protein
MHKMKOHG_03074	0.0	terL	-	-	S	-	-	-	Terminase
MHKMKOHG_03075	4.02e-79	-	-	-	L	-	-	-	Terminase, small subunit
MHKMKOHG_03076	4.4e-17	-	-	-	-	-	-	-	-
MHKMKOHG_03078	4.27e-64	-	-	-	-	-	-	-	-
MHKMKOHG_03079	1.52e-287	-	-	-	KL	-	-	-	SNF2 family N-terminal domain
MHKMKOHG_03080	1.74e-42	-	-	-	S	-	-	-	VRR_NUC
MHKMKOHG_03081	0.0	-	-	-	L	-	-	-	Virulence-associated protein E
MHKMKOHG_03085	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase A domain
MHKMKOHG_03086	5.57e-06	-	-	-	-	-	-	-	-
MHKMKOHG_03087	4.5e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
MHKMKOHG_03088	2.01e-204	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
MHKMKOHG_03089	5.63e-16	-	-	-	-	-	-	-	-
MHKMKOHG_03090	1.52e-58	-	-	-	-	-	-	-	-
MHKMKOHG_03092	1.14e-44	-	-	-	S	-	-	-	Uncharacterized protein YqaH
MHKMKOHG_03094	1.05e-40	-	-	-	-	-	-	-	-
MHKMKOHG_03095	2.73e-26	-	-	-	-	-	-	-	-
MHKMKOHG_03096	9.02e-69	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MHKMKOHG_03097	6.93e-71	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MHKMKOHG_03098	4.28e-191	-	-	-	S	-	-	-	Pfam:Arm-DNA-bind_4
MHKMKOHG_03099	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MHKMKOHG_03100	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MHKMKOHG_03101	1.23e-293	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHKMKOHG_03102	1.75e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MHKMKOHG_03103	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MHKMKOHG_03104	2.97e-83	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MHKMKOHG_03105	4.1e-183	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MHKMKOHG_03106	1.15e-135	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MHKMKOHG_03107	8.74e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHKMKOHG_03108	5.08e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
MHKMKOHG_03109	2.25e-70	yusE	-	-	CO	-	-	-	Thioredoxin
MHKMKOHG_03110	6.71e-77	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
MHKMKOHG_03111	2.99e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
MHKMKOHG_03112	1.19e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MHKMKOHG_03113	1.39e-81	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MHKMKOHG_03114	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MHKMKOHG_03115	1.5e-275	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MHKMKOHG_03116	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MHKMKOHG_03117	1.72e-10	-	-	-	S	-	-	-	YuzL-like protein
MHKMKOHG_03118	6.14e-205	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MHKMKOHG_03119	7.03e-53	-	-	-	-	-	-	-	-
MHKMKOHG_03120	3.53e-69	yusN	-	-	M	-	-	-	Coat F domain
MHKMKOHG_03121	1.47e-86	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MHKMKOHG_03122	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
MHKMKOHG_03123	1.46e-50	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
MHKMKOHG_03124	1.06e-191	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHKMKOHG_03125	9.75e-63	-	-	-	S	-	-	-	YusW-like protein
MHKMKOHG_03126	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MHKMKOHG_03127	4.34e-178	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKMKOHG_03128	1.38e-101	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MHKMKOHG_03129	5.23e-296	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHKMKOHG_03130	1.69e-159	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_03131	2.77e-316	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_03132	2.68e-32	-	-	-	-	-	-	-	-
MHKMKOHG_03133	1.28e-196	yuxN	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03134	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHKMKOHG_03135	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
MHKMKOHG_03136	3.61e-44	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MHKMKOHG_03137	2.79e-246	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MHKMKOHG_03138	6.05e-235	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MHKMKOHG_03139	5.95e-244	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MHKMKOHG_03140	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHKMKOHG_03141	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_03142	6.74e-159	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MHKMKOHG_03143	4.64e-166	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MHKMKOHG_03144	2.98e-128	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MHKMKOHG_03145	1.05e-64	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
MHKMKOHG_03146	9.45e-281	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_03147	9.16e-124	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MHKMKOHG_03148	3.6e-255	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MHKMKOHG_03149	4.7e-223	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_03150	4.34e-211	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MHKMKOHG_03151	1.43e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKMKOHG_03152	2.36e-213	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MHKMKOHG_03153	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
MHKMKOHG_03154	4.48e-171	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_03155	1.14e-48	-	-	-	-	-	-	-	-
MHKMKOHG_03156	1.53e-132	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MHKMKOHG_03157	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
MHKMKOHG_03158	9.98e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MHKMKOHG_03159	8.29e-80	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
MHKMKOHG_03160	1.62e-187	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MHKMKOHG_03161	4.01e-218	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_03162	2.48e-233	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_03163	2.48e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MHKMKOHG_03164	4.59e-155	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MHKMKOHG_03165	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MHKMKOHG_03166	4.34e-19	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
MHKMKOHG_03167	1.68e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MHKMKOHG_03168	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
MHKMKOHG_03169	9.77e-205	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
MHKMKOHG_03170	4.22e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MHKMKOHG_03171	1.21e-128	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MHKMKOHG_03172	8.82e-146	yfiK	-	-	K	-	-	-	Regulator
MHKMKOHG_03173	1.22e-236	-	-	-	T	-	-	-	Histidine kinase
MHKMKOHG_03174	1.31e-215	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MHKMKOHG_03175	6.05e-234	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MHKMKOHG_03176	1.23e-230	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MHKMKOHG_03177	1.2e-198	yvgN	-	-	S	-	-	-	reductase
MHKMKOHG_03178	6.3e-110	yvgO	-	-	-	-	-	-	-
MHKMKOHG_03179	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MHKMKOHG_03180	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MHKMKOHG_03181	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MHKMKOHG_03182	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MHKMKOHG_03183	9.04e-130	yvgT	-	-	S	-	-	-	membrane
MHKMKOHG_03184	1.75e-186	-	-	-	S	-	-	-	Metallo-peptidase family M12
MHKMKOHG_03185	2.51e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MHKMKOHG_03186	2.06e-134	bdbD	-	-	O	-	-	-	Thioredoxin
MHKMKOHG_03187	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MHKMKOHG_03188	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MHKMKOHG_03189	3.12e-38	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
MHKMKOHG_03190	2.05e-61	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MHKMKOHG_03191	6.96e-240	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MHKMKOHG_03192	5.95e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHKMKOHG_03193	1.63e-314	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKMKOHG_03194	5.43e-57	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MHKMKOHG_03195	6.72e-221	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKMKOHG_03196	2.48e-178	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MHKMKOHG_03197	2.95e-149	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHKMKOHG_03198	1.57e-151	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MHKMKOHG_03199	1.27e-181	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MHKMKOHG_03200	1.74e-162	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MHKMKOHG_03201	2.71e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MHKMKOHG_03202	1.14e-203	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MHKMKOHG_03203	6.26e-177	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MHKMKOHG_03204	2.5e-60	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
MHKMKOHG_03206	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MHKMKOHG_03207	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHKMKOHG_03208	6.92e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MHKMKOHG_03209	9.24e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MHKMKOHG_03210	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
MHKMKOHG_03211	1.07e-89	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
MHKMKOHG_03212	1.09e-90	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MHKMKOHG_03213	1.17e-67	yvaP	-	-	K	-	-	-	transcriptional
MHKMKOHG_03214	1.05e-309	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MHKMKOHG_03215	1.02e-153	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MHKMKOHG_03216	6.18e-164	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHKMKOHG_03217	6.39e-153	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MHKMKOHG_03218	7.05e-158	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_03219	4.93e-143	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHKMKOHG_03220	2.26e-213	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHKMKOHG_03221	4.44e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHKMKOHG_03222	3.58e-262	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHKMKOHG_03223	3.5e-108	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MHKMKOHG_03224	1.2e-138	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHKMKOHG_03225	4.95e-217	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHKMKOHG_03226	5.4e-143	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MHKMKOHG_03227	3.48e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MHKMKOHG_03228	2.67e-125	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MHKMKOHG_03229	1.18e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
MHKMKOHG_03230	1.92e-150	yvbI	-	-	M	-	-	-	Membrane
MHKMKOHG_03231	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MHKMKOHG_03232	5.07e-103	yvbK	-	-	K	-	-	-	acetyltransferase
MHKMKOHG_03233	5.9e-260	-	-	-	EGP	-	-	-	Major facilitator Superfamily
MHKMKOHG_03234	2.66e-219	-	-	-	-	-	-	-	-
MHKMKOHG_03235	3.54e-159	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MHKMKOHG_03236	1.13e-182	-	-	-	C	-	-	-	WbqC-like protein family
MHKMKOHG_03237	2.49e-179	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
MHKMKOHG_03238	1.28e-276	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MHKMKOHG_03239	1.31e-214	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
MHKMKOHG_03240	1.81e-273	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MHKMKOHG_03241	3.74e-316	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHKMKOHG_03242	8.09e-286	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
MHKMKOHG_03243	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHKMKOHG_03244	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MHKMKOHG_03245	1.49e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHKMKOHG_03246	4.45e-274	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MHKMKOHG_03247	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHKMKOHG_03248	8.1e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHKMKOHG_03250	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHKMKOHG_03251	7.16e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MHKMKOHG_03252	1.78e-241	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKMKOHG_03253	5.29e-161	yvbU	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03254	5.35e-196	yvbV	-	-	EG	-	-	-	EamA-like transporter family
MHKMKOHG_03255	6.69e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MHKMKOHG_03257	1.01e-190	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
MHKMKOHG_03258	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MHKMKOHG_03259	5.33e-288	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MHKMKOHG_03260	3.8e-168	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHKMKOHG_03261	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MHKMKOHG_03262	1.69e-170	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MHKMKOHG_03263	8.82e-266	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MHKMKOHG_03264	1.16e-151	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MHKMKOHG_03265	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MHKMKOHG_03266	1.97e-294	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MHKMKOHG_03267	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
MHKMKOHG_03268	1.43e-226	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
MHKMKOHG_03269	5.64e-275	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
MHKMKOHG_03270	1.2e-68	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MHKMKOHG_03271	1.4e-133	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHKMKOHG_03272	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKMKOHG_03273	1.25e-241	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHKMKOHG_03274	2.19e-249	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
MHKMKOHG_03275	8.53e-245	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MHKMKOHG_03276	5.24e-257	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
MHKMKOHG_03277	1.54e-250	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MHKMKOHG_03278	1.99e-199	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
MHKMKOHG_03279	3.63e-270	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
MHKMKOHG_03280	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MHKMKOHG_03281	3.12e-151	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MHKMKOHG_03282	3.08e-151	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MHKMKOHG_03283	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
MHKMKOHG_03284	1.01e-310	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
MHKMKOHG_03286	3.95e-109	ywjB	-	-	H	-	-	-	RibD C-terminal domain
MHKMKOHG_03287	3.14e-166	-	-	-	CH	-	-	-	FAD binding domain
MHKMKOHG_03288	3.66e-95	glx2	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MHKMKOHG_03289	4.11e-134	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
MHKMKOHG_03290	8.61e-107	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHKMKOHG_03291	7.09e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MHKMKOHG_03292	3.95e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
MHKMKOHG_03293	2.05e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MHKMKOHG_03294	5.99e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
MHKMKOHG_03295	3.64e-290	-	-	-	I	-	-	-	Pfam Lipase (class 3)
MHKMKOHG_03296	2.17e-44	-	-	-	-	-	-	-	-
MHKMKOHG_03298	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MHKMKOHG_03299	1.45e-278	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
MHKMKOHG_03300	3.26e-227	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MHKMKOHG_03301	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHKMKOHG_03302	1.4e-202	yraN	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03303	6.94e-262	yraM	-	-	S	-	-	-	PrpF protein
MHKMKOHG_03304	1.99e-314	-	-	-	EGP	-	-	-	Sugar (and other) transporter
MHKMKOHG_03305	5.28e-111	-	-	-	-	-	-	-	-
MHKMKOHG_03306	2.87e-132	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MHKMKOHG_03307	9.93e-65	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MHKMKOHG_03308	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
MHKMKOHG_03309	8.55e-135	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MHKMKOHG_03310	7.72e-229	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHKMKOHG_03311	4.11e-100	-	-	-	M	-	-	-	Ribonuclease
MHKMKOHG_03312	1.37e-165	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
MHKMKOHG_03313	6.52e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MHKMKOHG_03314	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MHKMKOHG_03315	3.51e-223	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MHKMKOHG_03316	1.41e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MHKMKOHG_03317	2.98e-112	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHKMKOHG_03318	4.78e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHKMKOHG_03319	4.88e-195	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
MHKMKOHG_03320	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MHKMKOHG_03321	1.17e-230	sasA	-	-	T	-	-	-	Histidine kinase
MHKMKOHG_03322	4.28e-153	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_03323	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MHKMKOHG_03324	7.18e-138	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MHKMKOHG_03325	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHKMKOHG_03326	9.97e-162	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHKMKOHG_03327	2.13e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHKMKOHG_03328	7.58e-134	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MHKMKOHG_03329	2.03e-280	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHKMKOHG_03330	1.45e-145	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHKMKOHG_03331	7.1e-257	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHKMKOHG_03332	3.83e-173	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
MHKMKOHG_03333	1.2e-110	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MHKMKOHG_03334	1.91e-156	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MHKMKOHG_03335	1.76e-193	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHKMKOHG_03336	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHKMKOHG_03337	1.22e-272	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHKMKOHG_03338	1.44e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHKMKOHG_03339	5.85e-169	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MHKMKOHG_03341	6.76e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
MHKMKOHG_03342	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MHKMKOHG_03343	1.09e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MHKMKOHG_03344	8.1e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MHKMKOHG_03345	2.91e-214	yvlB	-	-	S	-	-	-	Putative adhesin
MHKMKOHG_03346	1.79e-61	yvlA	-	-	-	-	-	-	-
MHKMKOHG_03347	1.29e-40	yvkN	-	-	-	-	-	-	-
MHKMKOHG_03348	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHKMKOHG_03349	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHKMKOHG_03350	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03351	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
MHKMKOHG_03352	1.59e-119	yvkB	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03353	3.49e-290	yvkA	-	-	P	-	-	-	-transporter
MHKMKOHG_03355	5.67e-278	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHKMKOHG_03356	5.83e-72	swrA	-	-	S	-	-	-	Swarming motility protein
MHKMKOHG_03357	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MHKMKOHG_03358	2.11e-275	ywoF	-	-	P	-	-	-	Right handed beta helix region
MHKMKOHG_03359	1.48e-196	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MHKMKOHG_03360	3.53e-158	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MHKMKOHG_03361	1.2e-57	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MHKMKOHG_03362	5.39e-189	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHKMKOHG_03363	1.08e-222	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHKMKOHG_03364	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHKMKOHG_03365	4.25e-130	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHKMKOHG_03366	1.92e-89	-	-	-	-	-	-	-	-
MHKMKOHG_03367	1.57e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MHKMKOHG_03368	2.18e-83	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MHKMKOHG_03369	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MHKMKOHG_03370	1.42e-153	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MHKMKOHG_03371	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MHKMKOHG_03372	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MHKMKOHG_03373	2.99e-103	yviE	-	-	-	-	-	-	-
MHKMKOHG_03374	6.64e-206	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MHKMKOHG_03375	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MHKMKOHG_03376	1.43e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
MHKMKOHG_03377	5.05e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
MHKMKOHG_03378	6.15e-95	yvyF	-	-	S	-	-	-	flagellar protein
MHKMKOHG_03379	2.57e-81	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MHKMKOHG_03380	2.93e-56	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
MHKMKOHG_03381	1.24e-120	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHKMKOHG_03382	3.69e-162	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MHKMKOHG_03383	9.46e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03384	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHKMKOHG_03385	5.43e-244	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MHKMKOHG_03386	6.65e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MHKMKOHG_03387	4.55e-234	yvhJ	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03388	8.94e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MHKMKOHG_03389	3.2e-285	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MHKMKOHG_03390	9.06e-182	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MHKMKOHG_03391	8.08e-138	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
MHKMKOHG_03392	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
MHKMKOHG_03393	3.03e-312	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHKMKOHG_03394	1.86e-268	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
MHKMKOHG_03395	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MHKMKOHG_03396	8.51e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MHKMKOHG_03397	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MHKMKOHG_03398	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
MHKMKOHG_03399	6.25e-63	-	-	-	-	-	-	-	-
MHKMKOHG_03400	2.48e-201	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MHKMKOHG_03401	1.62e-263	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHKMKOHG_03402	4.2e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MHKMKOHG_03403	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHKMKOHG_03404	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MHKMKOHG_03405	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHKMKOHG_03406	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MHKMKOHG_03407	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MHKMKOHG_03408	1.18e-179	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHKMKOHG_03409	3.41e-259	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MHKMKOHG_03410	1.91e-294	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHKMKOHG_03411	1.7e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MHKMKOHG_03412	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
MHKMKOHG_03413	3.04e-221	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MHKMKOHG_03414	4.89e-262	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
MHKMKOHG_03415	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
MHKMKOHG_03416	9.21e-304	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHKMKOHG_03417	1.73e-224	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03418	1.33e-195	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MHKMKOHG_03419	5.61e-60	yttA	-	-	S	-	-	-	Pfam Transposase IS66
MHKMKOHG_03420	4.57e-287	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MHKMKOHG_03421	1.16e-28	ywtC	-	-	-	-	-	-	-
MHKMKOHG_03422	7.41e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MHKMKOHG_03423	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
MHKMKOHG_03424	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
MHKMKOHG_03425	1.33e-243	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MHKMKOHG_03426	5.7e-227	-	-	-	E	-	-	-	Spore germination protein
MHKMKOHG_03427	1.59e-247	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
MHKMKOHG_03428	1.08e-221	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MHKMKOHG_03429	6.79e-193	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHKMKOHG_03430	3.64e-81	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHKMKOHG_03431	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MHKMKOHG_03432	7.29e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MHKMKOHG_03433	1.28e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MHKMKOHG_03434	5.4e-112	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
MHKMKOHG_03435	1.22e-114	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
MHKMKOHG_03436	4.33e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MHKMKOHG_03437	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MHKMKOHG_03438	6.98e-211	alsR	-	-	K	-	-	-	LysR substrate binding domain
MHKMKOHG_03440	2.8e-295	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHKMKOHG_03441	8.96e-150	ywrJ	-	-	-	-	-	-	-
MHKMKOHG_03442	2.39e-161	cotB	-	-	-	ko:K06325	-	ko00000	-
MHKMKOHG_03443	2.14e-259	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
MHKMKOHG_03444	2.4e-09	-	-	-	-	-	-	-	-
MHKMKOHG_03445	4.9e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MHKMKOHG_03446	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MHKMKOHG_03447	9.36e-106	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
MHKMKOHG_03448	1.24e-124	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
MHKMKOHG_03449	2.03e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MHKMKOHG_03450	5.23e-130	-	-	-	-	-	-	-	-
MHKMKOHG_03451	2.39e-81	-	-	-	-	-	-	-	-
MHKMKOHG_03452	1.92e-25	-	-	-	-	-	-	-	-
MHKMKOHG_03453	5.41e-76	-	-	-	S	-	-	-	SUKH-4 immunity protein
MHKMKOHG_03454	5.72e-290	ywqJ	-	-	S	-	-	-	Pre-toxin TG
MHKMKOHG_03455	1.36e-48	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
MHKMKOHG_03457	7.14e-184	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
MHKMKOHG_03458	6.02e-305	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MHKMKOHG_03459	3.26e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MHKMKOHG_03460	3.37e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MHKMKOHG_03461	1.7e-143	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MHKMKOHG_03462	3e-22	-	-	-	-	-	-	-	-
MHKMKOHG_03463	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
MHKMKOHG_03464	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MHKMKOHG_03465	5.43e-195	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MHKMKOHG_03466	2.67e-178	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MHKMKOHG_03467	4.94e-75	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MHKMKOHG_03468	1.83e-74	ywpG	-	-	-	-	-	-	-
MHKMKOHG_03469	1.79e-89	ywpF	-	-	S	-	-	-	YwpF-like protein
MHKMKOHG_03470	2.54e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHKMKOHG_03471	6.36e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHKMKOHG_03472	4.41e-247	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
MHKMKOHG_03473	1.25e-176	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MHKMKOHG_03474	1.16e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MHKMKOHG_03475	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MHKMKOHG_03476	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MHKMKOHG_03477	1.07e-92	ywoH	-	-	K	-	-	-	transcriptional
MHKMKOHG_03478	3.92e-270	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MHKMKOHG_03479	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
MHKMKOHG_03480	1.28e-308	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
MHKMKOHG_03481	2.1e-128	yjgF	-	-	Q	-	-	-	Isochorismatase family
MHKMKOHG_03482	8.91e-290	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MHKMKOHG_03483	1.07e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
MHKMKOHG_03484	3.87e-263	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MHKMKOHG_03485	5.56e-130	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MHKMKOHG_03486	1.44e-89	ywnJ	-	-	S	-	-	-	VanZ like family
MHKMKOHG_03487	1.17e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MHKMKOHG_03488	7.6e-113	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
MHKMKOHG_03490	2.45e-88	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
MHKMKOHG_03491	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHKMKOHG_03492	2.8e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
MHKMKOHG_03493	4.57e-117	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MHKMKOHG_03494	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03495	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MHKMKOHG_03496	4.37e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
MHKMKOHG_03497	2.26e-65	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
MHKMKOHG_03498	2.41e-16	csbD	-	-	K	-	-	-	CsbD-like
MHKMKOHG_03499	2.48e-106	ywmF	-	-	S	-	-	-	Peptidase M50
MHKMKOHG_03500	1.02e-114	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MHKMKOHG_03501	3.46e-242	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MHKMKOHG_03502	2.05e-183	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MHKMKOHG_03504	2.79e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MHKMKOHG_03505	4.74e-145	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MHKMKOHG_03506	8.36e-233	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MHKMKOHG_03507	1.85e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHKMKOHG_03508	4.45e-170	ywmB	-	-	S	-	-	-	TATA-box binding
MHKMKOHG_03509	7.55e-44	ywzB	-	-	S	-	-	-	membrane
MHKMKOHG_03510	1.98e-115	ywmA	-	-	-	-	-	-	-
MHKMKOHG_03511	3.36e-82	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MHKMKOHG_03512	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHKMKOHG_03513	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHKMKOHG_03514	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHKMKOHG_03515	5.59e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHKMKOHG_03516	3.35e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHKMKOHG_03517	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHKMKOHG_03518	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MHKMKOHG_03519	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
MHKMKOHG_03520	1.3e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHKMKOHG_03521	5.69e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHKMKOHG_03522	1.44e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MHKMKOHG_03523	9.2e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MHKMKOHG_03524	1.84e-95	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHKMKOHG_03525	5.32e-116	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MHKMKOHG_03526	2.33e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHKMKOHG_03527	6.75e-96	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
MHKMKOHG_03528	2.02e-147	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MHKMKOHG_03529	3.32e-76	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
MHKMKOHG_03531	1.01e-195	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHKMKOHG_03532	2.06e-240	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHKMKOHG_03533	2.41e-84	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKMKOHG_03534	3.73e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MHKMKOHG_03535	6.87e-194	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MHKMKOHG_03536	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
MHKMKOHG_03537	6.49e-131	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MHKMKOHG_03538	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
MHKMKOHG_03539	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHKMKOHG_03540	9.65e-223	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MHKMKOHG_03541	1.59e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHKMKOHG_03542	3.69e-143	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHKMKOHG_03543	4.53e-203	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MHKMKOHG_03544	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
MHKMKOHG_03545	2.24e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MHKMKOHG_03546	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHKMKOHG_03547	1.97e-74	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHKMKOHG_03548	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MHKMKOHG_03549	3.56e-262	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MHKMKOHG_03550	3.25e-225	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MHKMKOHG_03551	3.23e-58	ywjC	-	-	-	-	-	-	-
MHKMKOHG_03552	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MHKMKOHG_03553	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHKMKOHG_03554	2.78e-150	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
MHKMKOHG_03555	8.77e-110	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
MHKMKOHG_03556	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MHKMKOHG_03557	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHKMKOHG_03558	1e-97	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
MHKMKOHG_03559	2.46e-161	ywiC	-	-	S	-	-	-	YwiC-like protein
MHKMKOHG_03560	7.09e-163	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
MHKMKOHG_03561	3.08e-266	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MHKMKOHG_03562	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MHKMKOHG_03563	1.09e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03565	5.71e-251	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
MHKMKOHG_03566	5.55e-103	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
MHKMKOHG_03568	2.45e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MHKMKOHG_03569	6.45e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MHKMKOHG_03570	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MHKMKOHG_03571	1.61e-92	-	-	-	-	-	-	-	-
MHKMKOHG_03572	2.07e-116	ywhD	-	-	S	-	-	-	YwhD family
MHKMKOHG_03573	1.1e-152	ywhC	-	-	S	-	-	-	Peptidase family M50
MHKMKOHG_03574	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MHKMKOHG_03575	3.29e-90	ywhA	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03576	6.8e-307	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
MHKMKOHG_03577	1.37e-113	ywgA	-	-	-	ko:K09388	-	ko00000	-
MHKMKOHG_03578	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MHKMKOHG_03579	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
MHKMKOHG_03580	6.18e-139	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
MHKMKOHG_03581	2.99e-65	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
MHKMKOHG_03582	2.51e-109	-	-	-	S	-	-	-	membrane
MHKMKOHG_03583	2.86e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_03584	2.13e-208	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MHKMKOHG_03587	1.87e-209	-	-	-	-	-	-	-	-
MHKMKOHG_03589	8.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MHKMKOHG_03590	1.33e-199	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
MHKMKOHG_03591	9.29e-207	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MHKMKOHG_03592	2.27e-222	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MHKMKOHG_03593	1.9e-184	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MHKMKOHG_03594	2.12e-179	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
MHKMKOHG_03595	2.27e-290	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
MHKMKOHG_03596	9.5e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
MHKMKOHG_03597	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MHKMKOHG_03598	4.47e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_03599	1.63e-174	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MHKMKOHG_03600	1.83e-142	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MHKMKOHG_03601	1.97e-277	ywfA	-	-	EGP	-	-	-	-transporter
MHKMKOHG_03602	9.16e-252	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MHKMKOHG_03603	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHKMKOHG_03604	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MHKMKOHG_03605	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MHKMKOHG_03606	5e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MHKMKOHG_03607	4.02e-80	-	-	-	-	-	-	-	-
MHKMKOHG_03608	2.6e-109	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
MHKMKOHG_03609	5.7e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHKMKOHG_03610	1.33e-226	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHKMKOHG_03611	4.12e-170	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHKMKOHG_03612	2.22e-214	spsG	-	-	M	-	-	-	Spore Coat
MHKMKOHG_03613	1.52e-159	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
MHKMKOHG_03614	5.99e-266	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
MHKMKOHG_03615	6.34e-195	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
MHKMKOHG_03616	4.47e-276	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MHKMKOHG_03617	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
MHKMKOHG_03618	1.18e-179	spsA	-	-	M	-	-	-	Spore Coat
MHKMKOHG_03619	1.83e-83	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MHKMKOHG_03620	1.79e-75	ywdK	-	-	S	-	-	-	small membrane protein
MHKMKOHG_03621	6e-288	ywdJ	-	-	F	-	-	-	Xanthine uracil
MHKMKOHG_03622	9.54e-57	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
MHKMKOHG_03623	2.42e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHKMKOHG_03624	1.44e-186	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
MHKMKOHG_03625	2.79e-185	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MHKMKOHG_03626	6.09e-27	ywdA	-	-	-	-	-	-	-
MHKMKOHG_03627	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MHKMKOHG_03628	4.52e-316	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_03629	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MHKMKOHG_03631	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHKMKOHG_03632	6.39e-234	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MHKMKOHG_03633	1.46e-149	-	-	-	K	-	-	-	WYL domain
MHKMKOHG_03634	2.11e-162	ucpA	-	-	IQ	-	-	-	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHKMKOHG_03635	1.08e-54	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
MHKMKOHG_03636	4.81e-42	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
MHKMKOHG_03637	1.1e-176	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
MHKMKOHG_03638	7e-267	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MHKMKOHG_03639	7.44e-91	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
MHKMKOHG_03640	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MHKMKOHG_03641	1.08e-80	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MHKMKOHG_03642	2.84e-143	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MHKMKOHG_03643	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MHKMKOHG_03644	3.01e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MHKMKOHG_03645	5.74e-48	ydaS	-	-	S	-	-	-	membrane
MHKMKOHG_03646	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MHKMKOHG_03647	2.26e-267	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHKMKOHG_03648	1.57e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
MHKMKOHG_03649	2.98e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHKMKOHG_03651	6.64e-162	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
MHKMKOHG_03652	1.5e-157	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
MHKMKOHG_03653	5.3e-137	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MHKMKOHG_03654	1.39e-296	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
MHKMKOHG_03655	1.17e-190	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
MHKMKOHG_03656	2.95e-247	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
MHKMKOHG_03657	1.92e-139	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHKMKOHG_03658	4.76e-164	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHKMKOHG_03659	6.58e-200	ywbI	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03660	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MHKMKOHG_03661	4.37e-142	ywbG	-	-	M	-	-	-	effector of murein hydrolase
MHKMKOHG_03662	8.79e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
MHKMKOHG_03663	9.07e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MHKMKOHG_03664	5.06e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
MHKMKOHG_03665	1.23e-310	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHKMKOHG_03666	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MHKMKOHG_03667	2.87e-205	gspA	-	-	M	-	-	-	General stress
MHKMKOHG_03669	2.16e-150	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MHKMKOHG_03670	7.25e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
MHKMKOHG_03671	3.51e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MHKMKOHG_03672	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_03673	2.45e-289	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
MHKMKOHG_03674	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHKMKOHG_03675	2.84e-285	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHKMKOHG_03676	1.51e-258	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MHKMKOHG_03677	9.4e-317	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MHKMKOHG_03678	3.97e-66	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_03679	7.19e-314	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHKMKOHG_03680	3.67e-65	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
MHKMKOHG_03681	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MHKMKOHG_03682	1.21e-140	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MHKMKOHG_03683	7.43e-217	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_03684	2.19e-227	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MHKMKOHG_03685	1.53e-212	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MHKMKOHG_03686	4.16e-64	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MHKMKOHG_03687	6.72e-286	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MHKMKOHG_03688	3.25e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_03689	6.25e-63	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_03690	2.61e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHKMKOHG_03691	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHKMKOHG_03692	2.52e-204	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MHKMKOHG_03693	2.9e-225	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MHKMKOHG_03694	2.23e-259	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
MHKMKOHG_03695	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MHKMKOHG_03696	1.03e-237	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MHKMKOHG_03697	3.03e-315	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MHKMKOHG_03698	1.75e-191	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHKMKOHG_03699	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
MHKMKOHG_03700	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
MHKMKOHG_03701	5.93e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
MHKMKOHG_03702	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MHKMKOHG_03703	4.14e-283	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
MHKMKOHG_03704	3.39e-191	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
MHKMKOHG_03705	8.75e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MHKMKOHG_03706	1.43e-196	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MHKMKOHG_03707	2.79e-189	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHKMKOHG_03708	2.1e-117	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MHKMKOHG_03709	8.55e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MHKMKOHG_03710	1.57e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MHKMKOHG_03713	5.42e-105	yxjI	-	-	S	-	-	-	LURP-one-related
MHKMKOHG_03714	3.66e-274	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MHKMKOHG_03715	3.6e-188	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
MHKMKOHG_03716	7.13e-262	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHKMKOHG_03717	6.34e-111	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
MHKMKOHG_03718	3.23e-60	yxiS	-	-	-	-	-	-	-
MHKMKOHG_03719	3.04e-221	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
MHKMKOHG_03720	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MHKMKOHG_03721	1.57e-281	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
MHKMKOHG_03722	4.82e-176	bglS	-	-	M	-	-	-	licheninase activity
MHKMKOHG_03723	3e-183	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MHKMKOHG_03724	6.47e-276	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MHKMKOHG_03725	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MHKMKOHG_03728	1.13e-77	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
MHKMKOHG_03729	4.2e-103	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
MHKMKOHG_03731	3.62e-28	-	-	-	-	-	-	-	-
MHKMKOHG_03732	4.4e-10	yxiJ	-	-	S	-	-	-	YxiJ-like protein
MHKMKOHG_03733	3.14e-140	-	-	-	-	-	-	-	-
MHKMKOHG_03734	8.87e-72	-	-	-	-	-	-	-	-
MHKMKOHG_03735	1.02e-85	yxiG	-	-	-	-	-	-	-
MHKMKOHG_03737	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
MHKMKOHG_03738	2.04e-252	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
MHKMKOHG_03739	8.65e-201	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MHKMKOHG_03740	2.44e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
MHKMKOHG_03741	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MHKMKOHG_03742	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MHKMKOHG_03744	0.0	-	-	-	L	-	-	-	HKD family nuclease
MHKMKOHG_03745	2.8e-84	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MHKMKOHG_03746	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MHKMKOHG_03747	4.06e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MHKMKOHG_03748	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MHKMKOHG_03749	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MHKMKOHG_03750	4.43e-290	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MHKMKOHG_03751	3.33e-216	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MHKMKOHG_03752	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHKMKOHG_03753	2.59e-295	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MHKMKOHG_03754	3.31e-264	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MHKMKOHG_03755	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHKMKOHG_03756	9.22e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MHKMKOHG_03757	1.23e-188	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MHKMKOHG_03760	7.69e-30	yxeE	-	-	-	-	-	-	-
MHKMKOHG_03762	9.67e-33	yxeD	-	-	-	-	-	-	-
MHKMKOHG_03764	7.03e-220	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MHKMKOHG_03765	1.85e-71	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MHKMKOHG_03766	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MHKMKOHG_03767	1.23e-177	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MHKMKOHG_03768	2.77e-224	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_03769	3.66e-156	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_03770	3.8e-193	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MHKMKOHG_03771	1.15e-198	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MHKMKOHG_03772	1.72e-209	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
MHKMKOHG_03773	1.94e-245	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MHKMKOHG_03774	2.37e-290	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MHKMKOHG_03775	8.24e-217	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHKMKOHG_03776	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MHKMKOHG_03777	5.19e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MHKMKOHG_03778	2.24e-196	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MHKMKOHG_03779	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MHKMKOHG_03780	1.75e-174	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MHKMKOHG_03781	5.36e-219	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MHKMKOHG_03782	2.13e-311	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHKMKOHG_03783	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MHKMKOHG_03784	1.56e-188	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MHKMKOHG_03785	2.06e-129	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MHKMKOHG_03786	1.57e-243	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_03787	1.04e-247	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MHKMKOHG_03788	4.37e-265	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MHKMKOHG_03789	5.9e-314	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MHKMKOHG_03790	1.05e-185	yxaL	-	-	S	-	-	-	PQQ-like domain
MHKMKOHG_03791	1.01e-75	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
MHKMKOHG_03792	2.01e-66	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MHKMKOHG_03793	1.65e-250	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MHKMKOHG_03794	4.47e-87	yxaI	-	-	S	-	-	-	membrane protein domain
MHKMKOHG_03795	9.32e-154	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
MHKMKOHG_03796	1.55e-134	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
MHKMKOHG_03797	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
MHKMKOHG_03798	4.01e-231	mrjp	-	-	G	-	-	-	Major royal jelly protein
MHKMKOHG_03799	6.23e-302	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
MHKMKOHG_03800	3.35e-202	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
MHKMKOHG_03801	3.61e-96	-	-	-	K	-	-	-	Integron-associated effector binding protein
MHKMKOHG_03802	5.19e-97	yjhE	-	-	S	-	-	-	Phage tail protein
MHKMKOHG_03803	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
MHKMKOHG_03804	1.87e-100	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MHKMKOHG_03805	9.98e-184	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MHKMKOHG_03806	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MHKMKOHG_03807	4.6e-108	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MHKMKOHG_03808	1.33e-213	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MHKMKOHG_03809	1.46e-205	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
MHKMKOHG_03810	3.3e-27	-	-	-	-	-	-	-	-
MHKMKOHG_03811	0.0	-	-	-	L	-	-	-	AAA domain
MHKMKOHG_03813	3.7e-52	-	-	-	-	-	-	-	-
MHKMKOHG_03814	2.89e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHKMKOHG_03817	3.42e-259	yycP	-	-	-	-	-	-	-
MHKMKOHG_03818	1.08e-165	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MHKMKOHG_03819	2.87e-161	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MHKMKOHG_03821	5.6e-66	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MHKMKOHG_03822	7.95e-127	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	COG0785 Cytochrome c biogenesis protein
MHKMKOHG_03824	3.54e-105	yycN	-	-	K	-	-	-	Acetyltransferase
MHKMKOHG_03826	7.15e-257	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MHKMKOHG_03827	8.84e-211	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MHKMKOHG_03828	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MHKMKOHG_03829	8.65e-296	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MHKMKOHG_03830	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MHKMKOHG_03831	3.06e-250	-	-	-	S	-	-	-	Major Facilitator Superfamily
MHKMKOHG_03832	4.44e-309	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MHKMKOHG_03833	3.35e-119	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
MHKMKOHG_03834	1.71e-86	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MHKMKOHG_03835	4.99e-273	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MHKMKOHG_03836	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MHKMKOHG_03837	1.1e-191	yycI	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03838	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03839	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MHKMKOHG_03840	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MHKMKOHG_03847	4.45e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHKMKOHG_03848	1.06e-92	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKMKOHG_03849	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MHKMKOHG_03850	9e-38	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MHKMKOHG_03852	3.6e-25	yycC	-	-	K	-	-	-	YycC-like protein
MHKMKOHG_03853	4.92e-274	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MHKMKOHG_03854	1.59e-243	-	-	-	S	-	-	-	Ecdysteroid kinase
MHKMKOHG_03855	4.08e-291	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
MHKMKOHG_03856	8.3e-281	-	-	-	M	-	-	-	Glycosyltransferase Family 4
MHKMKOHG_03857	4.17e-155	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
MHKMKOHG_03858	1.11e-105	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
MHKMKOHG_03859	2.25e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MHKMKOHG_03860	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MHKMKOHG_03861	4.48e-191	yybS	-	-	S	-	-	-	membrane
MHKMKOHG_03863	3.36e-105	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MHKMKOHG_03864	1.79e-84	yybR	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03865	4.01e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MHKMKOHG_03866	4.42e-192	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHKMKOHG_03867	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
MHKMKOHG_03868	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
MHKMKOHG_03869	7.08e-145	-	-	-	K	-	-	-	FCD domain
MHKMKOHG_03871	3.75e-53	-	-	-	CP	-	-	-	Membrane
MHKMKOHG_03873	2.63e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
MHKMKOHG_03874	2.66e-31	-	-	-	-	-	-	-	-
MHKMKOHG_03875	7.04e-24	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
MHKMKOHG_03877	5.34e-72	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MHKMKOHG_03878	1.56e-144	ydgI	-	-	C	-	-	-	nitroreductase
MHKMKOHG_03879	5.14e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MHKMKOHG_03880	9.98e-190	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MHKMKOHG_03881	7.24e-97	yybA	-	-	K	-	-	-	transcriptional
MHKMKOHG_03882	5.74e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MHKMKOHG_03883	7.1e-27	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MHKMKOHG_03884	7.06e-129	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MHKMKOHG_03885	2.63e-90	ynaF	-	-	-	-	-	-	-
MHKMKOHG_03886	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
MHKMKOHG_03887	1.66e-193	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MHKMKOHG_03888	2.4e-312	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
MHKMKOHG_03889	9.47e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHKMKOHG_03890	6.01e-217	ccpB	-	-	K	-	-	-	Transcriptional regulator
MHKMKOHG_03891	5.03e-179	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MHKMKOHG_03892	2.4e-114	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHKMKOHG_03893	5.31e-125	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MHKMKOHG_03894	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHKMKOHG_03895	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHKMKOHG_03896	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MHKMKOHG_03897	6.32e-253	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHKMKOHG_03898	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MHKMKOHG_03899	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MHKMKOHG_03900	1.9e-215	yyaD	-	-	S	-	-	-	Membrane
MHKMKOHG_03901	1.05e-95	yhhY	-	-	K	-	-	-	FR47-like protein
MHKMKOHG_03902	1.3e-139	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MHKMKOHG_03903	6.79e-188	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MHKMKOHG_03904	1.37e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MHKMKOHG_03905	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MHKMKOHG_03906	4.96e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MHKMKOHG_03907	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHKMKOHG_03908	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHKMKOHG_03909	1.43e-136	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MHKMKOHG_03910	6.08e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHKMKOHG_03911	5.27e-67	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme