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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HIMOHAPL_00001	4.17e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HIMOHAPL_00002	2.45e-58	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HIMOHAPL_00003	1.3e-90	-	-	-	L	-	-	-	RelB antitoxin
HIMOHAPL_00005	1.29e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HIMOHAPL_00006	3.65e-109	-	-	-	M	-	-	-	NlpC/P60 family
HIMOHAPL_00009	1.2e-50	-	-	-	-	-	-	-	-
HIMOHAPL_00010	6.94e-210	-	-	-	EG	-	-	-	EamA-like transporter family
HIMOHAPL_00011	2.68e-131	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HIMOHAPL_00012	4.94e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HIMOHAPL_00013	9.93e-213	-	-	-	EG	-	-	-	EamA-like transporter family
HIMOHAPL_00014	2.04e-149	yicL	-	-	EG	-	-	-	EamA-like transporter family
HIMOHAPL_00015	1.88e-137	-	-	-	-	-	-	-	-
HIMOHAPL_00016	5.25e-142	-	-	-	-	-	-	-	-
HIMOHAPL_00017	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
HIMOHAPL_00018	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HIMOHAPL_00019	2.99e-114	-	-	-	-	-	-	-	-
HIMOHAPL_00020	1.09e-74	-	-	-	-	-	-	-	-
HIMOHAPL_00021	3.92e-39	-	-	-	S	-	-	-	Protein conserved in bacteria
HIMOHAPL_00022	2.49e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIMOHAPL_00023	1.33e-310	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIMOHAPL_00024	5.74e-240	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIMOHAPL_00027	1.84e-263	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HIMOHAPL_00028	1.79e-242	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HIMOHAPL_00029	1.3e-85	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HIMOHAPL_00030	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIMOHAPL_00031	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HIMOHAPL_00032	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HIMOHAPL_00033	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_00034	4.86e-280	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HIMOHAPL_00035	5.01e-170	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HIMOHAPL_00036	1.66e-42	-	-	-	-	-	-	-	-
HIMOHAPL_00037	4.7e-89	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HIMOHAPL_00038	1.99e-201	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_00040	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HIMOHAPL_00041	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HIMOHAPL_00042	0.0	-	-	-	S	-	-	-	TerB-C domain
HIMOHAPL_00043	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HIMOHAPL_00044	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HIMOHAPL_00045	1.59e-78	-	-	-	-	-	-	-	-
HIMOHAPL_00046	7.76e-183	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HIMOHAPL_00048	2.84e-80	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HIMOHAPL_00049	5.34e-146	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HIMOHAPL_00050	1.09e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HIMOHAPL_00052	1.04e-41	-	-	-	-	-	-	-	-
HIMOHAPL_00053	1.32e-218	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HIMOHAPL_00054	1.25e-17	-	-	-	-	-	-	-	-
HIMOHAPL_00055	1.35e-150	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_00056	3.67e-35	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_00057	1.39e-132	-	-	-	M	-	-	-	LysM domain protein
HIMOHAPL_00058	8.45e-213	-	-	-	D	-	-	-	nuclear chromosome segregation
HIMOHAPL_00059	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HIMOHAPL_00060	1.49e-113	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HIMOHAPL_00061	3.25e-145	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HIMOHAPL_00062	6.02e-145	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HIMOHAPL_00064	1.29e-280	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HIMOHAPL_00065	1.3e-240	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HIMOHAPL_00066	7.71e-157	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HIMOHAPL_00067	1.43e-186	-	-	-	K	-	-	-	SIS domain
HIMOHAPL_00068	1.66e-309	slpX	-	-	S	-	-	-	SLAP domain
HIMOHAPL_00069	6.39e-32	-	-	-	S	-	-	-	transposase or invertase
HIMOHAPL_00070	1.48e-14	-	-	-	-	-	-	-	-
HIMOHAPL_00071	2.18e-305	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HIMOHAPL_00074	2.75e-79	-	-	-	-	-	-	-	-
HIMOHAPL_00076	9.73e-120	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
HIMOHAPL_00077	7.41e-65	-	-	-	-	-	-	-	-
HIMOHAPL_00079	2.45e-27	-	-	-	-	-	-	-	-
HIMOHAPL_00081	8.02e-16	-	-	-	K	-	-	-	transcriptional
HIMOHAPL_00082	2.61e-281	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HIMOHAPL_00083	0.0	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIMOHAPL_00084	1.53e-232	-	-	-	-	-	-	-	-
HIMOHAPL_00085	1.87e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HIMOHAPL_00086	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HIMOHAPL_00087	5.23e-172	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HIMOHAPL_00088	3.07e-263	-	-	-	M	-	-	-	Glycosyl transferases group 1
HIMOHAPL_00089	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIMOHAPL_00090	6.65e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIMOHAPL_00091	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HIMOHAPL_00092	1.07e-285	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HIMOHAPL_00093	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HIMOHAPL_00094	2.33e-174	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HIMOHAPL_00095	9.14e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HIMOHAPL_00097	3.29e-127	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HIMOHAPL_00098	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HIMOHAPL_00099	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIMOHAPL_00100	1.04e-266	camS	-	-	S	-	-	-	sex pheromone
HIMOHAPL_00101	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMOHAPL_00102	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIMOHAPL_00103	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMOHAPL_00104	9.65e-220	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HIMOHAPL_00105	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HIMOHAPL_00106	1.46e-75	-	-	-	-	-	-	-	-
HIMOHAPL_00107	7.35e-129	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HIMOHAPL_00108	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HIMOHAPL_00109	1.01e-256	flp	-	-	V	-	-	-	Beta-lactamase
HIMOHAPL_00110	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIMOHAPL_00111	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_00116	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HIMOHAPL_00117	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIMOHAPL_00118	5.02e-40	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HIMOHAPL_00119	1.19e-308	-	-	-	L	-	-	-	DDE superfamily endonuclease
HIMOHAPL_00120	1.4e-111	vatD	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	acetyltransferase'
HIMOHAPL_00121	5.99e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HIMOHAPL_00122	5.69e-39	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HIMOHAPL_00123	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HIMOHAPL_00124	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIMOHAPL_00125	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIMOHAPL_00126	6.43e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HIMOHAPL_00127	2.06e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
HIMOHAPL_00128	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIMOHAPL_00129	4.15e-186	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HIMOHAPL_00130	8.07e-155	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HIMOHAPL_00131	3.12e-273	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_00132	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIMOHAPL_00133	1.9e-172	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HIMOHAPL_00134	3.45e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIMOHAPL_00135	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HIMOHAPL_00136	5.7e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIMOHAPL_00137	2.75e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIMOHAPL_00138	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HIMOHAPL_00139	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIMOHAPL_00140	1.89e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_00141	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIMOHAPL_00142	1.56e-231	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIMOHAPL_00143	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HIMOHAPL_00144	3.98e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIMOHAPL_00145	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_00146	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_00147	8.71e-15	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_00148	3.06e-181	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIMOHAPL_00149	2.27e-220	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_00150	2.57e-226	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIMOHAPL_00151	1.21e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIMOHAPL_00152	1.48e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIMOHAPL_00153	1.75e-231	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIMOHAPL_00154	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIMOHAPL_00155	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HIMOHAPL_00156	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HIMOHAPL_00157	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HIMOHAPL_00158	7.76e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HIMOHAPL_00159	2.61e-154	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HIMOHAPL_00160	6.22e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIMOHAPL_00161	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HIMOHAPL_00162	1.98e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HIMOHAPL_00163	3.18e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIMOHAPL_00164	2.55e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIMOHAPL_00165	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIMOHAPL_00166	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIMOHAPL_00167	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HIMOHAPL_00168	2.19e-100	-	-	-	S	-	-	-	ASCH
HIMOHAPL_00169	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HIMOHAPL_00170	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HIMOHAPL_00171	4.72e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HIMOHAPL_00172	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMOHAPL_00173	1.97e-248	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMOHAPL_00174	7.19e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIMOHAPL_00175	3.38e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIMOHAPL_00176	7.98e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HIMOHAPL_00177	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIMOHAPL_00178	1.24e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HIMOHAPL_00179	3.94e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HIMOHAPL_00180	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HIMOHAPL_00181	1.5e-193	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMOHAPL_00182	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HIMOHAPL_00185	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HIMOHAPL_00186	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HIMOHAPL_00187	6.57e-206	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HIMOHAPL_00188	3.48e-271	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIMOHAPL_00190	3.02e-228	lipA	-	-	I	-	-	-	Carboxylesterase family
HIMOHAPL_00191	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HIMOHAPL_00192	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIMOHAPL_00193	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIMOHAPL_00194	7.49e-195	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HIMOHAPL_00195	4.33e-69	-	-	-	-	-	-	-	-
HIMOHAPL_00196	8.51e-50	-	-	-	-	-	-	-	-
HIMOHAPL_00197	1.9e-56	-	-	-	S	-	-	-	Alpha beta hydrolase
HIMOHAPL_00198	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HIMOHAPL_00199	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HIMOHAPL_00200	8.74e-62	-	-	-	-	-	-	-	-
HIMOHAPL_00201	1.17e-190	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HIMOHAPL_00202	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HIMOHAPL_00203	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HIMOHAPL_00204	3.47e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HIMOHAPL_00205	2.04e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIMOHAPL_00206	2.22e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HIMOHAPL_00207	1.38e-120	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIMOHAPL_00208	5.1e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIMOHAPL_00209	9.01e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIMOHAPL_00210	2.73e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIMOHAPL_00212	2.81e-50	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HIMOHAPL_00213	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HIMOHAPL_00214	2.76e-60	-	-	-	-	-	-	-	-
HIMOHAPL_00215	1.54e-151	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HIMOHAPL_00216	2.08e-71	-	-	-	-	-	-	-	-
HIMOHAPL_00217	4.15e-36	-	-	-	-	-	-	-	-
HIMOHAPL_00218	1.24e-89	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HIMOHAPL_00221	4.05e-202	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HIMOHAPL_00222	4.38e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_00223	1.12e-135	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HIMOHAPL_00224	9.05e-152	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HIMOHAPL_00225	5.18e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HIMOHAPL_00226	2.7e-161	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HIMOHAPL_00227	5.08e-207	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HIMOHAPL_00228	2.42e-33	-	-	-	-	-	-	-	-
HIMOHAPL_00229	3.43e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIMOHAPL_00230	1.99e-235	-	-	-	S	-	-	-	AAA domain
HIMOHAPL_00231	2.49e-65	-	-	-	-	-	-	-	-
HIMOHAPL_00232	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HIMOHAPL_00233	1.91e-70	-	-	-	-	-	-	-	-
HIMOHAPL_00234	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HIMOHAPL_00235	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIMOHAPL_00236	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIMOHAPL_00237	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HIMOHAPL_00238	1.26e-100	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIMOHAPL_00239	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMOHAPL_00240	3.81e-123	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HIMOHAPL_00241	1.19e-45	-	-	-	-	-	-	-	-
HIMOHAPL_00242	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HIMOHAPL_00243	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIMOHAPL_00244	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIMOHAPL_00245	3.01e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HIMOHAPL_00246	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIMOHAPL_00247	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIMOHAPL_00248	9.47e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HIMOHAPL_00249	1.19e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HIMOHAPL_00250	1.82e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HIMOHAPL_00251	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIMOHAPL_00252	9.4e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIMOHAPL_00253	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HIMOHAPL_00254	1.18e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HIMOHAPL_00255	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIMOHAPL_00256	8.77e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIMOHAPL_00257	1.08e-175	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMOHAPL_00258	6.7e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMOHAPL_00259	1.02e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMOHAPL_00260	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HIMOHAPL_00261	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMOHAPL_00262	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIMOHAPL_00263	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIMOHAPL_00264	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HIMOHAPL_00265	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIMOHAPL_00266	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIMOHAPL_00267	1.25e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIMOHAPL_00268	4.95e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HIMOHAPL_00269	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HIMOHAPL_00270	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIMOHAPL_00271	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIMOHAPL_00272	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIMOHAPL_00273	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIMOHAPL_00274	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMOHAPL_00275	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIMOHAPL_00276	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIMOHAPL_00277	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIMOHAPL_00278	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIMOHAPL_00279	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HIMOHAPL_00280	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIMOHAPL_00281	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIMOHAPL_00282	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIMOHAPL_00283	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIMOHAPL_00284	4.01e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIMOHAPL_00285	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIMOHAPL_00286	2.6e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HIMOHAPL_00287	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIMOHAPL_00288	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HIMOHAPL_00289	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIMOHAPL_00290	6.89e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIMOHAPL_00291	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIMOHAPL_00292	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HIMOHAPL_00293	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMOHAPL_00294	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMOHAPL_00295	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HIMOHAPL_00296	7.84e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HIMOHAPL_00302	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HIMOHAPL_00303	2.37e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIMOHAPL_00304	1.37e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIMOHAPL_00305	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIMOHAPL_00306	3.35e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIMOHAPL_00307	3.95e-82	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HIMOHAPL_00308	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HIMOHAPL_00309	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
HIMOHAPL_00310	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIMOHAPL_00311	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIMOHAPL_00312	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HIMOHAPL_00313	1.23e-166	-	-	-	S	-	-	-	(CBS) domain
HIMOHAPL_00314	2.3e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIMOHAPL_00315	9.39e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIMOHAPL_00316	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIMOHAPL_00317	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIMOHAPL_00318	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HIMOHAPL_00319	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HIMOHAPL_00320	3.18e-198	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIMOHAPL_00321	1.57e-103	-	-	-	E	-	-	-	amino acid
HIMOHAPL_00322	2.72e-252	-	-	-	E	-	-	-	amino acid
HIMOHAPL_00323	1.62e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIMOHAPL_00324	3.35e-56	-	-	-	-	-	-	-	-
HIMOHAPL_00325	1.01e-69	-	-	-	-	-	-	-	-
HIMOHAPL_00326	1.2e-238	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
HIMOHAPL_00327	1.08e-180	-	-	-	P	-	-	-	Voltage gated chloride channel
HIMOHAPL_00328	7.57e-303	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HIMOHAPL_00329	1.03e-95	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HIMOHAPL_00330	2.49e-115	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HIMOHAPL_00331	1.57e-128	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HIMOHAPL_00332	1.03e-05	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein
HIMOHAPL_00333	5.52e-08	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN_bind
HIMOHAPL_00334	1.95e-20	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HIMOHAPL_00335	8.4e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HIMOHAPL_00336	8.58e-228	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HIMOHAPL_00338	3.47e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIMOHAPL_00339	1.94e-130	-	-	-	I	-	-	-	PAP2 superfamily
HIMOHAPL_00340	1.28e-189	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HIMOHAPL_00341	3.52e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIMOHAPL_00342	5.21e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HIMOHAPL_00343	8.05e-83	yfhC	-	-	C	-	-	-	nitroreductase
HIMOHAPL_00344	1.18e-12	yfhC	-	-	C	-	-	-	nitroreductase
HIMOHAPL_00345	9.87e-203	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIMOHAPL_00346	2.78e-297	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIMOHAPL_00347	4.06e-39	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_00348	3.62e-289	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_00349	7.23e-55	-	-	-	-	-	-	-	-
HIMOHAPL_00350	4.15e-172	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HIMOHAPL_00351	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIMOHAPL_00352	4.04e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HIMOHAPL_00353	1.59e-78	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HIMOHAPL_00354	1.32e-74	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HIMOHAPL_00355	3.28e-166	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
HIMOHAPL_00356	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIMOHAPL_00357	6.11e-118	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
HIMOHAPL_00358	3.14e-226	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HIMOHAPL_00359	9.44e-110	-	-	-	-	-	-	-	-
HIMOHAPL_00360	1.83e-54	-	-	-	C	-	-	-	FMN_bind
HIMOHAPL_00361	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HIMOHAPL_00362	1.53e-251	pbpX1	-	-	V	-	-	-	Beta-lactamase
HIMOHAPL_00363	2.21e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIMOHAPL_00364	4.67e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HIMOHAPL_00365	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIMOHAPL_00366	1.49e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIMOHAPL_00367	1.98e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIMOHAPL_00368	2.12e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIMOHAPL_00369	4.84e-313	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIMOHAPL_00370	7.93e-121	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_00371	6.76e-70	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_00372	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HIMOHAPL_00373	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIMOHAPL_00374	1.22e-159	potE	-	-	E	-	-	-	Amino Acid
HIMOHAPL_00375	1.51e-20	-	-	-	-	-	-	-	-
HIMOHAPL_00376	3.9e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HIMOHAPL_00377	3.55e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIMOHAPL_00378	1.09e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIMOHAPL_00379	4.06e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIMOHAPL_00380	1.98e-193	-	-	-	-	-	-	-	-
HIMOHAPL_00381	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMOHAPL_00382	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIMOHAPL_00383	6.28e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HIMOHAPL_00384	2.57e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HIMOHAPL_00385	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HIMOHAPL_00386	1e-121	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HIMOHAPL_00387	2.98e-246	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HIMOHAPL_00388	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIMOHAPL_00389	3.01e-125	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HIMOHAPL_00390	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HIMOHAPL_00391	3.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HIMOHAPL_00392	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HIMOHAPL_00393	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIMOHAPL_00394	1.09e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HIMOHAPL_00395	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMOHAPL_00396	4.5e-234	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HIMOHAPL_00397	0.0	-	-	-	L	-	-	-	Nuclease-related domain
HIMOHAPL_00398	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIMOHAPL_00399	2.31e-148	-	-	-	S	-	-	-	repeat protein
HIMOHAPL_00400	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HIMOHAPL_00401	1.9e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIMOHAPL_00402	2.97e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HIMOHAPL_00403	9.21e-267	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HIMOHAPL_00404	2.83e-145	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIMOHAPL_00405	1.8e-57	-	-	-	-	-	-	-	-
HIMOHAPL_00406	1.27e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HIMOHAPL_00407	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HIMOHAPL_00408	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIMOHAPL_00409	4.44e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HIMOHAPL_00410	8.08e-192	ylmH	-	-	S	-	-	-	S4 domain protein
HIMOHAPL_00411	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HIMOHAPL_00412	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIMOHAPL_00413	9.61e-305	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIMOHAPL_00414	7.64e-310	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIMOHAPL_00415	7.72e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIMOHAPL_00416	1.16e-265	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIMOHAPL_00417	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIMOHAPL_00418	4.43e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIMOHAPL_00419	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HIMOHAPL_00420	9.31e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HIMOHAPL_00421	4.45e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIMOHAPL_00422	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HIMOHAPL_00423	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HIMOHAPL_00424	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HIMOHAPL_00425	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HIMOHAPL_00426	4.1e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HIMOHAPL_00427	5.81e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HIMOHAPL_00428	1.07e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HIMOHAPL_00429	3.7e-163	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HIMOHAPL_00430	1.73e-306	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HIMOHAPL_00431	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIMOHAPL_00432	1.68e-66	-	-	-	-	-	-	-	-
HIMOHAPL_00433	3.02e-166	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HIMOHAPL_00434	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HIMOHAPL_00435	6.52e-17	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HIMOHAPL_00436	2.09e-59	-	-	-	-	-	-	-	-
HIMOHAPL_00437	1.36e-122	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HIMOHAPL_00438	4.96e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HIMOHAPL_00439	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
HIMOHAPL_00440	1.89e-48	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HIMOHAPL_00441	1.48e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HIMOHAPL_00442	3.75e-196	-	-	-	-	-	-	-	-
HIMOHAPL_00443	2.48e-171	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_00444	7.79e-144	-	-	-	-	-	-	-	-
HIMOHAPL_00445	7.91e-06	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMOHAPL_00448	1.02e-232	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIMOHAPL_00449	1.93e-149	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HIMOHAPL_00450	5.72e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIMOHAPL_00451	4.85e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIMOHAPL_00452	4.78e-242	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
HIMOHAPL_00454	7.37e-85	-	-	-	-	-	-	-	-
HIMOHAPL_00455	1.59e-48	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HIMOHAPL_00456	1.05e-156	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HIMOHAPL_00457	9.19e-74	-	-	-	E	-	-	-	Ornithine cyclodeaminase/mu-crystallin family
HIMOHAPL_00458	0.0	-	-	-	E	-	-	-	Amino acid permease
HIMOHAPL_00459	0.0	-	-	-	M	-	-	-	MobA-like NTP transferase domain
HIMOHAPL_00460	6.6e-179	-	-	-	M	-	-	-	MobA-like NTP transferase domain
HIMOHAPL_00461	1.25e-105	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HIMOHAPL_00462	1.43e-226	epsIIL	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HIMOHAPL_00463	5.7e-262	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HIMOHAPL_00464	2.19e-110	-	-	-	M	-	-	-	Glycosyl transferase family 2
HIMOHAPL_00465	2.53e-33	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HIMOHAPL_00467	8.73e-105	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HIMOHAPL_00468	5.4e-117	-	-	-	M	-	-	-	Glycosyl transferase family 2
HIMOHAPL_00469	8e-145	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HIMOHAPL_00470	5.46e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HIMOHAPL_00471	1.79e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HIMOHAPL_00472	3.89e-187	epsB	-	-	M	-	-	-	biosynthesis protein
HIMOHAPL_00473	3.46e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HIMOHAPL_00474	5.52e-55	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIMOHAPL_00476	1.8e-289	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIMOHAPL_00477	7.27e-223	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HIMOHAPL_00479	7.04e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HIMOHAPL_00480	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HIMOHAPL_00481	7.67e-124	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HIMOHAPL_00482	1.44e-122	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HIMOHAPL_00483	4.7e-58	-	-	-	-	-	-	-	-
HIMOHAPL_00484	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HIMOHAPL_00485	8.77e-144	-	-	-	-	-	-	-	-
HIMOHAPL_00486	1.17e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HIMOHAPL_00487	6.85e-227	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMOHAPL_00488	4.05e-102	-	-	-	-	-	-	-	-
HIMOHAPL_00489	1.06e-141	-	-	-	S	-	-	-	Peptidase_C39 like family
HIMOHAPL_00490	4.26e-108	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HIMOHAPL_00491	2.2e-175	-	-	-	S	-	-	-	Putative threonine/serine exporter
HIMOHAPL_00492	0.0	-	-	-	S	-	-	-	ABC transporter
HIMOHAPL_00493	7.25e-83	-	-	-	-	-	-	-	-
HIMOHAPL_00494	4.4e-132	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HIMOHAPL_00495	2.04e-46	-	-	-	-	-	-	-	-
HIMOHAPL_00496	3.14e-157	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HIMOHAPL_00497	5.21e-277	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HIMOHAPL_00498	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HIMOHAPL_00499	8.31e-18	-	-	-	S	-	-	-	Fic/DOC family
HIMOHAPL_00500	7.27e-42	-	-	-	-	-	-	-	-
HIMOHAPL_00501	1.79e-92	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
HIMOHAPL_00502	4.12e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HIMOHAPL_00503	3.98e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIMOHAPL_00504	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HIMOHAPL_00505	2.52e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HIMOHAPL_00506	8.97e-141	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HIMOHAPL_00507	5.5e-188	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HIMOHAPL_00508	1.18e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HIMOHAPL_00509	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HIMOHAPL_00510	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HIMOHAPL_00511	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HIMOHAPL_00512	1.29e-278	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HIMOHAPL_00513	1.21e-209	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_00514	4.41e-41	-	-	-	-	-	-	-	-
HIMOHAPL_00515	1.01e-12	-	-	-	-	-	-	-	-
HIMOHAPL_00516	2.55e-74	-	-	-	-	-	-	-	-
HIMOHAPL_00517	2.24e-33	-	-	-	-	-	-	-	-
HIMOHAPL_00518	2.58e-41	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HIMOHAPL_00519	5.53e-100	-	-	-	-	-	-	-	-
HIMOHAPL_00520	8.52e-21	-	-	-	-	-	-	-	-
HIMOHAPL_00521	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HIMOHAPL_00522	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HIMOHAPL_00523	4.48e-34	-	-	-	-	-	-	-	-
HIMOHAPL_00524	2.17e-35	-	-	-	-	-	-	-	-
HIMOHAPL_00525	4.61e-44	-	-	-	-	-	-	-	-
HIMOHAPL_00526	1.4e-69	-	-	-	S	-	-	-	Enterocin A Immunity
HIMOHAPL_00527	1.39e-179	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HIMOHAPL_00528	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIMOHAPL_00529	1.32e-270	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HIMOHAPL_00530	8.32e-157	vanR	-	-	K	-	-	-	response regulator
HIMOHAPL_00531	1.31e-51	-	-	-	S	-	-	-	HicB family
HIMOHAPL_00532	6.07e-261	-	-	-	L	-	-	-	Probable transposase
HIMOHAPL_00534	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HIMOHAPL_00535	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_00536	5.87e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HIMOHAPL_00537	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIMOHAPL_00538	4.49e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HIMOHAPL_00539	3.01e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HIMOHAPL_00540	4.99e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HIMOHAPL_00541	1.61e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HIMOHAPL_00542	3.66e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HIMOHAPL_00543	2.99e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
HIMOHAPL_00545	3.03e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIMOHAPL_00546	9.48e-194	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HIMOHAPL_00547	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HIMOHAPL_00548	1.39e-124	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HIMOHAPL_00549	1.07e-144	-	-	-	K	-	-	-	WHG domain
HIMOHAPL_00550	6.73e-51	-	-	-	-	-	-	-	-
HIMOHAPL_00551	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIMOHAPL_00552	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_00553	4.28e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HIMOHAPL_00554	1.45e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIMOHAPL_00555	3.9e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
HIMOHAPL_00556	2.4e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HIMOHAPL_00557	5.05e-184	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HIMOHAPL_00558	5.5e-155	-	-	-	-	-	-	-	-
HIMOHAPL_00559	1.02e-199	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HIMOHAPL_00560	3.24e-128	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HIMOHAPL_00561	6.24e-110	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HIMOHAPL_00562	4.34e-22	-	-	-	-	-	-	-	-
HIMOHAPL_00563	8.21e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HIMOHAPL_00564	4.71e-166	-	-	-	S	-	-	-	membrane
HIMOHAPL_00565	6.23e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
HIMOHAPL_00566	1.15e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HIMOHAPL_00567	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HIMOHAPL_00568	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HIMOHAPL_00569	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
HIMOHAPL_00570	3.24e-224	-	-	-	-	-	-	-	-
HIMOHAPL_00571	2.09e-285	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HIMOHAPL_00572	0.0	-	-	-	-	-	-	-	-
HIMOHAPL_00573	7.84e-28	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HIMOHAPL_00574	2.76e-111	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HIMOHAPL_00575	2.16e-169	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HIMOHAPL_00576	3.09e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
HIMOHAPL_00577	2.17e-72	-	-	-	-	-	-	-	-
HIMOHAPL_00578	5.93e-61	-	-	-	S	-	-	-	MazG-like family
HIMOHAPL_00579	6.41e-76	-	-	-	-	-	-	-	-
HIMOHAPL_00580	6.55e-114	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_00581	1.98e-46	-	-	-	-	-	-	-	-
HIMOHAPL_00582	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HIMOHAPL_00583	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMOHAPL_00584	3.52e-293	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HIMOHAPL_00585	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIMOHAPL_00586	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HIMOHAPL_00587	1.4e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HIMOHAPL_00588	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HIMOHAPL_00589	1.13e-41	-	-	-	M	-	-	-	Lysin motif
HIMOHAPL_00590	4.39e-148	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIMOHAPL_00591	4.65e-168	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HIMOHAPL_00592	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIMOHAPL_00593	1.81e-169	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIMOHAPL_00594	7.97e-82	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMOHAPL_00595	9.98e-215	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HIMOHAPL_00596	2.55e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HIMOHAPL_00597	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HIMOHAPL_00598	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HIMOHAPL_00599	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HIMOHAPL_00600	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HIMOHAPL_00601	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HIMOHAPL_00602	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HIMOHAPL_00603	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HIMOHAPL_00604	8.69e-186	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMOHAPL_00605	1.75e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIMOHAPL_00606	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HIMOHAPL_00607	1.88e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIMOHAPL_00608	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIMOHAPL_00609	3.87e-141	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HIMOHAPL_00610	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HIMOHAPL_00611	1.98e-231	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMOHAPL_00612	3.84e-192	yxeH	-	-	S	-	-	-	hydrolase
HIMOHAPL_00613	5.94e-200	-	-	-	S	-	-	-	reductase
HIMOHAPL_00614	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
HIMOHAPL_00615	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIMOHAPL_00616	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HIMOHAPL_00617	1.42e-228	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIMOHAPL_00618	7.89e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIMOHAPL_00619	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HIMOHAPL_00620	5.41e-225	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HIMOHAPL_00621	5.31e-206	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HIMOHAPL_00622	1.35e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIMOHAPL_00623	2.34e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_00624	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIMOHAPL_00625	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HIMOHAPL_00626	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HIMOHAPL_00627	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HIMOHAPL_00628	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
HIMOHAPL_00629	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HIMOHAPL_00630	2.95e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HIMOHAPL_00631	5.39e-251	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HIMOHAPL_00632	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HIMOHAPL_00633	6.24e-215	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HIMOHAPL_00634	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HIMOHAPL_00635	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HIMOHAPL_00636	1.46e-31	-	-	-	-	-	-	-	-
HIMOHAPL_00637	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HIMOHAPL_00638	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_00639	6.28e-124	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HIMOHAPL_00640	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HIMOHAPL_00641	1.12e-13	-	-	-	-	-	-	-	-
HIMOHAPL_00642	2.93e-67	-	-	-	-	-	-	-	-
HIMOHAPL_00643	1.05e-226	citR	-	-	K	-	-	-	Putative sugar-binding domain
HIMOHAPL_00644	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HIMOHAPL_00645	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIMOHAPL_00646	7.96e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HIMOHAPL_00647	9.32e-81	-	-	-	-	-	-	-	-
HIMOHAPL_00648	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIMOHAPL_00649	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIMOHAPL_00650	4.28e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HIMOHAPL_00651	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HIMOHAPL_00652	5.51e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HIMOHAPL_00653	5.43e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIMOHAPL_00654	2.74e-12	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_00655	1.4e-208	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_00656	1.1e-96	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HIMOHAPL_00657	1.95e-61	-	-	-	-	-	-	-	-
HIMOHAPL_00658	8.84e-52	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_00659	6.93e-63	-	-	-	E	-	-	-	Zn peptidase
HIMOHAPL_00660	2.26e-250	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HIMOHAPL_00661	1.32e-133	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
HIMOHAPL_00662	5.52e-124	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HIMOHAPL_00663	3.24e-72	-	-	-	-	-	-	-	-
HIMOHAPL_00666	6.02e-78	-	-	-	-	-	-	-	-
HIMOHAPL_00667	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
HIMOHAPL_00669	2.29e-97	-	-	-	-	-	-	-	-
HIMOHAPL_00670	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HIMOHAPL_00671	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HIMOHAPL_00672	8.05e-278	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIMOHAPL_00673	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HIMOHAPL_00674	6.88e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HIMOHAPL_00675	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIMOHAPL_00676	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HIMOHAPL_00677	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HIMOHAPL_00678	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HIMOHAPL_00679	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HIMOHAPL_00680	1.05e-108	-	-	-	-	-	-	-	-
HIMOHAPL_00681	3.25e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HIMOHAPL_00682	1.83e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIMOHAPL_00683	5.6e-162	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIMOHAPL_00684	1.67e-175	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HIMOHAPL_00685	4.65e-206	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HIMOHAPL_00686	9.29e-111	usp5	-	-	T	-	-	-	universal stress protein
HIMOHAPL_00687	1.76e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HIMOHAPL_00688	3.77e-113	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIMOHAPL_00689	4.83e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HIMOHAPL_00691	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HIMOHAPL_00692	2.6e-81	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HIMOHAPL_00693	3.61e-61	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
HIMOHAPL_00694	4.72e-61	-	-	-	-	-	-	-	-
HIMOHAPL_00695	1.55e-42	-	-	-	-	-	-	-	-
HIMOHAPL_00696	2.45e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HIMOHAPL_00697	3.44e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HIMOHAPL_00698	1.6e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HIMOHAPL_00699	1.28e-274	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HIMOHAPL_00700	1.05e-272	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HIMOHAPL_00701	1.06e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HIMOHAPL_00702	7.74e-61	-	-	-	-	-	-	-	-
HIMOHAPL_00703	1.02e-224	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HIMOHAPL_00704	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIMOHAPL_00705	2.29e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HIMOHAPL_00706	1.74e-111	-	-	-	-	-	-	-	-
HIMOHAPL_00707	3.85e-98	-	-	-	-	-	-	-	-
HIMOHAPL_00708	1.24e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HIMOHAPL_00709	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HIMOHAPL_00710	2.3e-188	-	-	-	-	-	-	-	-
HIMOHAPL_00711	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HIMOHAPL_00713	1.18e-67	-	-	-	L	-	-	-	Transposase
HIMOHAPL_00714	5.09e-41	-	-	-	-	-	-	-	-
HIMOHAPL_00715	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HIMOHAPL_00716	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HIMOHAPL_00717	2.6e-37	-	-	-	-	-	-	-	-
HIMOHAPL_00718	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HIMOHAPL_00719	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIMOHAPL_00720	2.19e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIMOHAPL_00721	8.7e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HIMOHAPL_00722	6.73e-208	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HIMOHAPL_00723	4.04e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HIMOHAPL_00724	1.03e-144	-	-	-	S	-	-	-	CYTH
HIMOHAPL_00725	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HIMOHAPL_00726	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIMOHAPL_00727	4.61e-220	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HIMOHAPL_00728	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HIMOHAPL_00729	2.66e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
HIMOHAPL_00730	1.75e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HIMOHAPL_00731	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HIMOHAPL_00732	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HIMOHAPL_00733	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIMOHAPL_00734	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HIMOHAPL_00735	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HIMOHAPL_00736	1.71e-283	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HIMOHAPL_00737	9.49e-302	ymfH	-	-	S	-	-	-	Peptidase M16
HIMOHAPL_00738	6.87e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HIMOHAPL_00739	1.63e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HIMOHAPL_00740	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIMOHAPL_00741	2.02e-249	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIMOHAPL_00742	1.5e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HIMOHAPL_00743	1.94e-268	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HIMOHAPL_00744	5.04e-154	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HIMOHAPL_00745	2.34e-315	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HIMOHAPL_00746	3.57e-173	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HIMOHAPL_00747	2.9e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIMOHAPL_00748	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIMOHAPL_00749	3.19e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIMOHAPL_00750	1.02e-27	-	-	-	-	-	-	-	-
HIMOHAPL_00751	1.18e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIMOHAPL_00752	1.71e-204	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIMOHAPL_00753	5.73e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HIMOHAPL_00754	3.42e-232	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIMOHAPL_00755	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HIMOHAPL_00756	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIMOHAPL_00757	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIMOHAPL_00758	3.8e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HIMOHAPL_00759	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HIMOHAPL_00760	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HIMOHAPL_00761	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HIMOHAPL_00762	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIMOHAPL_00763	0.0	-	-	-	S	-	-	-	SH3-like domain
HIMOHAPL_00764	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_00765	5.56e-167	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HIMOHAPL_00766	3.92e-123	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HIMOHAPL_00767	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HIMOHAPL_00768	5.38e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HIMOHAPL_00769	2.78e-150	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIMOHAPL_00770	4.98e-116	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HIMOHAPL_00771	1.62e-61	-	-	-	K	-	-	-	LytTr DNA-binding domain
HIMOHAPL_00772	3.33e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HIMOHAPL_00773	2.21e-182	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HIMOHAPL_00774	0.0	ycaM	-	-	E	-	-	-	amino acid
HIMOHAPL_00775	0.0	-	-	-	-	-	-	-	-
HIMOHAPL_00777	1.35e-240	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HIMOHAPL_00778	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIMOHAPL_00779	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HIMOHAPL_00780	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIMOHAPL_00781	3.07e-124	-	-	-	-	-	-	-	-
HIMOHAPL_00782	1.7e-201	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIMOHAPL_00783	1.64e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIMOHAPL_00784	1.9e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HIMOHAPL_00785	5.86e-114	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HIMOHAPL_00786	1.51e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HIMOHAPL_00787	1.71e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HIMOHAPL_00788	3.58e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIMOHAPL_00789	1.65e-177	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_00790	2.6e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_00791	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIMOHAPL_00792	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIMOHAPL_00793	2.65e-219	ybbR	-	-	S	-	-	-	YbbR-like protein
HIMOHAPL_00794	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIMOHAPL_00795	5.66e-190	-	-	-	S	-	-	-	hydrolase
HIMOHAPL_00796	1.13e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HIMOHAPL_00797	2.44e-154	-	-	-	-	-	-	-	-
HIMOHAPL_00798	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIMOHAPL_00799	1.85e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HIMOHAPL_00800	5.06e-196	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HIMOHAPL_00801	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIMOHAPL_00802	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIMOHAPL_00803	1.15e-232	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HIMOHAPL_00804	0.0	-	-	-	E	-	-	-	Amino acid permease
HIMOHAPL_00806	4.8e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMOHAPL_00807	9.93e-143	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HIMOHAPL_00808	2.83e-121	-	-	-	S	-	-	-	VanZ like family
HIMOHAPL_00809	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HIMOHAPL_00810	2.39e-229	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HIMOHAPL_00811	5.15e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HIMOHAPL_00812	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HIMOHAPL_00813	8.52e-93	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HIMOHAPL_00814	1.68e-55	-	-	-	-	-	-	-	-
HIMOHAPL_00815	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HIMOHAPL_00816	6.14e-29	-	-	-	-	-	-	-	-
HIMOHAPL_00817	4.37e-241	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HIMOHAPL_00818	2.51e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIMOHAPL_00820	3.01e-128	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HIMOHAPL_00821	6.7e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HIMOHAPL_00822	6.45e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HIMOHAPL_00823	2.91e-86	-	-	-	S	-	-	-	SdpI/YhfL protein family
HIMOHAPL_00824	7.05e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HIMOHAPL_00825	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HIMOHAPL_00826	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIMOHAPL_00827	5.3e-137	vanZ	-	-	V	-	-	-	VanZ like family
HIMOHAPL_00828	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HIMOHAPL_00829	5.65e-275	-	-	-	EGP	-	-	-	Major Facilitator
HIMOHAPL_00830	9.67e-251	ampC	-	-	V	-	-	-	Beta-lactamase
HIMOHAPL_00833	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HIMOHAPL_00834	7.02e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HIMOHAPL_00835	1.89e-236	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIMOHAPL_00836	3.05e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIMOHAPL_00837	1.66e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIMOHAPL_00838	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIMOHAPL_00839	1.01e-166	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HIMOHAPL_00840	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMOHAPL_00841	2.48e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIMOHAPL_00842	1.61e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMOHAPL_00843	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIMOHAPL_00844	1.04e-221	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIMOHAPL_00845	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIMOHAPL_00846	2.45e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HIMOHAPL_00847	4.38e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HIMOHAPL_00848	8.31e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HIMOHAPL_00849	2.26e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HIMOHAPL_00850	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HIMOHAPL_00851	2.05e-276	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HIMOHAPL_00852	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
HIMOHAPL_00853	1.35e-56	-	-	-	-	-	-	-	-
HIMOHAPL_00854	5.13e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HIMOHAPL_00855	4.68e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HIMOHAPL_00856	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIMOHAPL_00857	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIMOHAPL_00858	4.28e-273	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HIMOHAPL_00859	9.99e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIMOHAPL_00861	6.03e-105	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_00862	1.6e-79	-	-	-	-	-	-	-	-
HIMOHAPL_00863	9.85e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
HIMOHAPL_00864	1.51e-45	-	-	-	-	-	-	-	-
HIMOHAPL_00865	6.94e-49	-	4.2.1.5	-	M	ko:K01683	-	ko00000,ko01000	Mandelate racemase muconate lactonizing enzyme
HIMOHAPL_00866	9.62e-214	-	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HIMOHAPL_00867	6.44e-264	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HIMOHAPL_00868	6e-175	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
HIMOHAPL_00869	3.26e-91	-	-	-	K	-	-	-	LysR substrate binding domain
HIMOHAPL_00870	1.7e-298	-	-	-	L	-	-	-	Transposase DDE domain
HIMOHAPL_00871	2.68e-158	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HIMOHAPL_00872	2.01e-207	dgoD	4.2.1.6, 4.2.1.8	-	M	ko:K01684,ko:K08323	ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Mandelate racemase muconate lactonizing enzyme
HIMOHAPL_00873	2.15e-134	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HIMOHAPL_00874	5.55e-59	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIMOHAPL_00875	6.08e-38	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HIMOHAPL_00876	8.38e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HIMOHAPL_00877	8.39e-151	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HIMOHAPL_00878	6.18e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HIMOHAPL_00879	1.1e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIMOHAPL_00880	1.58e-131	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HIMOHAPL_00881	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HIMOHAPL_00882	9.89e-74	-	-	-	-	-	-	-	-
HIMOHAPL_00883	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HIMOHAPL_00884	1.5e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HIMOHAPL_00885	3.37e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HIMOHAPL_00886	3.09e-71	-	-	-	-	-	-	-	-
HIMOHAPL_00887	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIMOHAPL_00888	1.74e-186	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HIMOHAPL_00889	4.9e-145	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIMOHAPL_00890	7.14e-187	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HIMOHAPL_00891	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HIMOHAPL_00892	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIMOHAPL_00893	5.37e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HIMOHAPL_00894	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIMOHAPL_00895	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HIMOHAPL_00896	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIMOHAPL_00897	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HIMOHAPL_00898	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIMOHAPL_00899	2.18e-304	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIMOHAPL_00900	5.46e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HIMOHAPL_00901	3.02e-275	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMOHAPL_00902	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIMOHAPL_00903	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HIMOHAPL_00904	1.39e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIMOHAPL_00905	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIMOHAPL_00906	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIMOHAPL_00907	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIMOHAPL_00908	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIMOHAPL_00909	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIMOHAPL_00910	3.25e-101	-	-	-	-	-	-	-	-
HIMOHAPL_00911	2.14e-231	-	-	-	M	-	-	-	CHAP domain
HIMOHAPL_00912	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIMOHAPL_00913	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HIMOHAPL_00914	5.27e-235	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIMOHAPL_00915	8.74e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIMOHAPL_00916	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HIMOHAPL_00917	5.37e-195	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HIMOHAPL_00918	5e-50	-	-	-	-	-	-	-	-
HIMOHAPL_00919	1.75e-294	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HIMOHAPL_00920	2.29e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIMOHAPL_00921	3.23e-124	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HIMOHAPL_00922	6.59e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HIMOHAPL_00923	4.5e-113	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HIMOHAPL_00924	4.83e-173	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HIMOHAPL_00925	1.84e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIMOHAPL_00926	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HIMOHAPL_00927	1.45e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HIMOHAPL_00928	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HIMOHAPL_00929	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIMOHAPL_00930	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HIMOHAPL_00931	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIMOHAPL_00932	1.55e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIMOHAPL_00933	1.92e-46	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
HIMOHAPL_00934	2.26e-55	-	-	-	M	-	-	-	family 8
HIMOHAPL_00935	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMOHAPL_00936	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIMOHAPL_00937	6.15e-36	-	-	-	-	-	-	-	-
HIMOHAPL_00938	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HIMOHAPL_00939	5.39e-188	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
HIMOHAPL_00940	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIMOHAPL_00941	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIMOHAPL_00943	0.0	-	-	-	S	-	-	-	PglZ domain
HIMOHAPL_00944	1.42e-39	-	-	-	K	-	-	-	Helix-turn-helix
HIMOHAPL_00945	1.97e-39	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HIMOHAPL_00950	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
HIMOHAPL_00951	1.76e-264	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HIMOHAPL_00952	8.18e-117	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HIMOHAPL_00953	1.48e-107	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HIMOHAPL_00954	3.54e-106	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIMOHAPL_00955	4.83e-167	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIMOHAPL_00956	0.0	-	-	-	C	-	-	-	FMN_bind
HIMOHAPL_00957	6.12e-288	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HIMOHAPL_00958	1.45e-139	-	-	-	K	-	-	-	LysR family
HIMOHAPL_00959	0.0	-	-	-	C	-	-	-	FMN_bind
HIMOHAPL_00960	5.77e-140	-	-	-	K	-	-	-	LysR family
HIMOHAPL_00961	2.05e-90	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HIMOHAPL_00962	1.16e-21	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HIMOHAPL_00963	7.06e-157	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HIMOHAPL_00964	3.47e-73	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HIMOHAPL_00965	1.39e-120	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HIMOHAPL_00966	5.15e-223	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HIMOHAPL_00967	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HIMOHAPL_00968	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HIMOHAPL_00969	2.76e-83	-	-	-	-	-	-	-	-
HIMOHAPL_00970	9.28e-157	-	-	-	L	-	-	-	Transposase
HIMOHAPL_00971	1.51e-140	-	-	-	L	-	-	-	Transposase
HIMOHAPL_00972	4.92e-204	-	-	-	-	-	-	-	-
HIMOHAPL_00973	2.88e-220	-	-	-	-	-	-	-	-
HIMOHAPL_00974	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HIMOHAPL_00975	7.16e-287	ynbB	-	-	P	-	-	-	aluminum resistance
HIMOHAPL_00976	1.98e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIMOHAPL_00977	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HIMOHAPL_00978	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HIMOHAPL_00979	5.39e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HIMOHAPL_00980	4.58e-125	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIMOHAPL_00981	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HIMOHAPL_00982	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HIMOHAPL_00983	0.0	-	-	-	S	-	-	-	membrane
HIMOHAPL_00984	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HIMOHAPL_00985	9.43e-52	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIMOHAPL_00986	3.33e-70	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HIMOHAPL_00987	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIMOHAPL_00988	5.21e-179	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HIMOHAPL_00989	8.02e-204	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMOHAPL_00990	8.41e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HIMOHAPL_00991	5.83e-147	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
HIMOHAPL_00992	1.28e-174	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HIMOHAPL_00993	9.86e-63	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIMOHAPL_00994	2.87e-107	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
HIMOHAPL_00995	1.85e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
HIMOHAPL_00996	2.92e-280	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
HIMOHAPL_00997	4.11e-294	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HIMOHAPL_00998	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIMOHAPL_00999	1.76e-193	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIMOHAPL_01000	9.61e-288	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HIMOHAPL_01001	4.18e-27	-	-	-	S	-	-	-	Transglycosylase associated protein
HIMOHAPL_01002	3.81e-18	-	-	-	S	-	-	-	CsbD-like
HIMOHAPL_01003	1.17e-213	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HIMOHAPL_01004	4.37e-213	degV1	-	-	S	-	-	-	DegV family
HIMOHAPL_01005	2.36e-218	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HIMOHAPL_01006	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HIMOHAPL_01007	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HIMOHAPL_01008	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HIMOHAPL_01009	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIMOHAPL_01010	7.46e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIMOHAPL_01011	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HIMOHAPL_01012	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMOHAPL_01013	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMOHAPL_01014	5.14e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIMOHAPL_01015	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HIMOHAPL_01016	5.71e-245	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIMOHAPL_01017	1.83e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIMOHAPL_01018	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HIMOHAPL_01019	1.87e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIMOHAPL_01020	3.37e-192	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMOHAPL_01021	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIMOHAPL_01022	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIMOHAPL_01023	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HIMOHAPL_01024	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIMOHAPL_01025	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HIMOHAPL_01026	3.98e-41	-	-	-	E	-	-	-	Zn peptidase
HIMOHAPL_01027	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01028	3.68e-177	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HIMOHAPL_01029	1.61e-307	-	-	-	V	-	-	-	MatE
HIMOHAPL_01030	4.67e-253	-	-	-	V	-	-	-	MatE
HIMOHAPL_01031	2.61e-164	-	-	-	GK	-	-	-	ROK family
HIMOHAPL_01032	2.8e-43	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HIMOHAPL_01033	3.95e-108	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HIMOHAPL_01034	8.24e-271	-	-	-	-	-	-	-	-
HIMOHAPL_01035	6.46e-27	-	-	-	-	-	-	-	-
HIMOHAPL_01036	1.83e-316	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HIMOHAPL_01037	3.14e-137	-	-	-	-	-	-	-	-
HIMOHAPL_01038	6.63e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HIMOHAPL_01039	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HIMOHAPL_01040	4.44e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HIMOHAPL_01041	1.2e-83	-	-	-	S	-	-	-	Cupredoxin-like domain
HIMOHAPL_01042	1.6e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HIMOHAPL_01043	8.67e-37	-	-	-	-	-	-	-	-
HIMOHAPL_01044	2.21e-293	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HIMOHAPL_01045	3.05e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HIMOHAPL_01046	1.34e-288	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HIMOHAPL_01047	2.73e-80	yneE	-	-	K	-	-	-	Transcriptional regulator
HIMOHAPL_01049	2.37e-53	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
HIMOHAPL_01050	4.22e-05	-	-	-	S	ko:K07124	-	ko00000	KR domain
HIMOHAPL_01051	5.05e-11	-	-	-	-	-	-	-	-
HIMOHAPL_01052	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HIMOHAPL_01053	3.28e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HIMOHAPL_01054	8.79e-154	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HIMOHAPL_01055	1.71e-187	-	-	-	S	-	-	-	ABC-2 family transporter protein
HIMOHAPL_01056	1.42e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIMOHAPL_01057	1.1e-28	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01058	7.3e-111	-	-	-	-	-	-	-	-
HIMOHAPL_01059	2.23e-299	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HIMOHAPL_01060	8.94e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIMOHAPL_01061	7.29e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HIMOHAPL_01062	7.3e-216	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIMOHAPL_01063	2.59e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIMOHAPL_01064	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HIMOHAPL_01065	2.12e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HIMOHAPL_01066	1.1e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HIMOHAPL_01067	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HIMOHAPL_01068	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
HIMOHAPL_01069	1.33e-175	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HIMOHAPL_01070	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HIMOHAPL_01071	1.52e-204	-	-	-	S	-	-	-	Phospholipase, patatin family
HIMOHAPL_01072	3.84e-191	-	-	-	S	-	-	-	hydrolase
HIMOHAPL_01073	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HIMOHAPL_01074	6.89e-190	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HIMOHAPL_01075	1.52e-103	-	-	-	-	-	-	-	-
HIMOHAPL_01076	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HIMOHAPL_01077	1.76e-52	-	-	-	-	-	-	-	-
HIMOHAPL_01078	3.04e-154	-	-	-	C	-	-	-	nitroreductase
HIMOHAPL_01079	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HIMOHAPL_01080	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HIMOHAPL_01081	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HIMOHAPL_01082	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HIMOHAPL_01083	1.29e-295	-	-	-	E	ko:K03294	-	ko00000	amino acid
HIMOHAPL_01084	6.12e-167	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIMOHAPL_01085	5.96e-283	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HIMOHAPL_01086	3.76e-316	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_01088	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIMOHAPL_01089	3.7e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HIMOHAPL_01090	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HIMOHAPL_01091	1.47e-105	-	-	-	C	-	-	-	Flavodoxin
HIMOHAPL_01092	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HIMOHAPL_01093	2.88e-310	ynbB	-	-	P	-	-	-	aluminum resistance
HIMOHAPL_01094	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HIMOHAPL_01095	0.0	-	-	-	E	-	-	-	Amino acid permease
HIMOHAPL_01096	9.58e-122	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
HIMOHAPL_01097	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HIMOHAPL_01098	3.78e-110	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HIMOHAPL_01099	2.52e-16	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HIMOHAPL_01100	1.25e-85	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMOHAPL_01101	9.28e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMOHAPL_01102	5.49e-197	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HIMOHAPL_01103	6.23e-121	-	-	-	M	-	-	-	LysM domain protein
HIMOHAPL_01104	9.09e-76	-	-	-	C	-	-	-	Aldo keto reductase
HIMOHAPL_01105	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HIMOHAPL_01106	1.15e-312	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HIMOHAPL_01107	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HIMOHAPL_01108	9.92e-179	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HIMOHAPL_01109	1.42e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HIMOHAPL_01110	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIMOHAPL_01111	3.03e-195	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HIMOHAPL_01112	8.96e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMOHAPL_01113	4.52e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIMOHAPL_01114	2.23e-237	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HIMOHAPL_01115	4.46e-89	-	-	-	P	-	-	-	NhaP-type Na H and K H
HIMOHAPL_01116	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HIMOHAPL_01117	8.63e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HIMOHAPL_01118	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HIMOHAPL_01119	5.13e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIMOHAPL_01120	1.35e-204	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMOHAPL_01121	3.34e-112	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
HIMOHAPL_01122	8.83e-90	yagE	-	-	E	-	-	-	Amino acid permease
HIMOHAPL_01123	2.67e-37	-	-	-	E	-	-	-	amino acid
HIMOHAPL_01124	3.91e-105	-	-	-	E	-	-	-	amino acid
HIMOHAPL_01125	7.23e-192	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
HIMOHAPL_01126	9.83e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
HIMOHAPL_01127	5.9e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HIMOHAPL_01128	7.43e-50	-	-	-	S	-	-	-	AAA domain
HIMOHAPL_01129	2.53e-151	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
HIMOHAPL_01130	2.84e-73	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
HIMOHAPL_01131	2.03e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HIMOHAPL_01141	5.79e-54	-	-	-	-	-	-	-	-
HIMOHAPL_01142	8.35e-75	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIMOHAPL_01143	2.99e-114	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIMOHAPL_01146	1.41e-29	-	-	-	-	-	-	-	-
HIMOHAPL_01147	5.5e-29	-	-	-	-	-	-	-	-
HIMOHAPL_01148	6.72e-27	-	-	-	-	-	-	-	-
HIMOHAPL_01150	6.49e-202	-	-	-	EP	-	-	-	Plasmid replication protein
HIMOHAPL_01151	8.21e-27	-	-	-	-	-	-	-	-
HIMOHAPL_01152	5.23e-237	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HIMOHAPL_01153	5.45e-40	-	-	-	-	-	-	-	-
HIMOHAPL_01155	1.29e-188	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HIMOHAPL_01156	5.35e-103	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
HIMOHAPL_01157	4.79e-74	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HIMOHAPL_01158	3.17e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HIMOHAPL_01159	3.18e-55	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HIMOHAPL_01160	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HIMOHAPL_01161	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_01162	2.54e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
HIMOHAPL_01163	1.37e-134	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HIMOHAPL_01164	1.26e-26	-	-	-	-	-	-	-	-
HIMOHAPL_01165	1.59e-315	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HIMOHAPL_01166	8.39e-104	-	-	-	E	-	-	-	Zn peptidase
HIMOHAPL_01167	2.48e-54	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01168	2.96e-56	-	-	-	-	-	-	-	-
HIMOHAPL_01169	4.19e-62	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HIMOHAPL_01170	5.26e-17	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01171	6.04e-60	-	-	-	-	-	-	-	-
HIMOHAPL_01172	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HIMOHAPL_01173	1.97e-72	-	-	-	-	-	-	-	-
HIMOHAPL_01175	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HIMOHAPL_01176	2.62e-159	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HIMOHAPL_01177	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIMOHAPL_01178	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIMOHAPL_01179	4.39e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIMOHAPL_01180	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMOHAPL_01181	6.71e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMOHAPL_01182	8.64e-253	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIMOHAPL_01183	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIMOHAPL_01184	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HIMOHAPL_01185	1.44e-94	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HIMOHAPL_01186	5.69e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIMOHAPL_01187	1.43e-144	-	-	-	-	-	-	-	-
HIMOHAPL_01189	7.04e-145	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HIMOHAPL_01190	4.07e-245	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HIMOHAPL_01191	7.41e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HIMOHAPL_01192	3.22e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HIMOHAPL_01193	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HIMOHAPL_01195	3.58e-146	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIMOHAPL_01197	3.03e-197	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIMOHAPL_01198	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIMOHAPL_01199	6.4e-188	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HIMOHAPL_01200	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIMOHAPL_01201	6.68e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIMOHAPL_01202	1.72e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HIMOHAPL_01203	6.12e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HIMOHAPL_01204	7.68e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIMOHAPL_01205	5.52e-113	-	-	-	-	-	-	-	-
HIMOHAPL_01206	0.0	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01207	5.4e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIMOHAPL_01208	1.26e-215	-	-	-	GK	-	-	-	ROK family
HIMOHAPL_01209	1.41e-48	-	-	-	-	-	-	-	-
HIMOHAPL_01210	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HIMOHAPL_01211	2.04e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HIMOHAPL_01212	1.1e-94	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIMOHAPL_01213	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIMOHAPL_01214	1.49e-309	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIMOHAPL_01215	1.79e-97	-	-	-	K	-	-	-	acetyltransferase
HIMOHAPL_01216	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIMOHAPL_01217	1.3e-199	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
HIMOHAPL_01218	5.15e-288	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HIMOHAPL_01219	7.92e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIMOHAPL_01220	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HIMOHAPL_01222	1.76e-33	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_01223	5.18e-57	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HIMOHAPL_01224	1.57e-258	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HIMOHAPL_01225	5.34e-245	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HIMOHAPL_01226	4.9e-199	-	-	-	C	-	-	-	Nitroreductase
HIMOHAPL_01228	2.3e-168	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HIMOHAPL_01229	3.57e-154	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HIMOHAPL_01230	6.46e-36	-	-	-	-	-	-	-	-
HIMOHAPL_01231	1.66e-305	-	-	-	E	-	-	-	amino acid
HIMOHAPL_01232	1.99e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HIMOHAPL_01233	4.48e-173	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HIMOHAPL_01234	7.16e-312	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HIMOHAPL_01235	6.49e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HIMOHAPL_01236	1.7e-147	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HIMOHAPL_01237	3.88e-150	-	-	-	V	-	-	-	ABC transporter transmembrane region
HIMOHAPL_01238	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HIMOHAPL_01239	1.36e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HIMOHAPL_01240	3.09e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_01241	1.32e-38	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01242	3.24e-90	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01243	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01244	1.96e-49	-	-	-	-	-	-	-	-
HIMOHAPL_01245	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HIMOHAPL_01246	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIMOHAPL_01247	6.14e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HIMOHAPL_01248	4.44e-224	pbpX2	-	-	V	-	-	-	Beta-lactamase
HIMOHAPL_01249	1.43e-310	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIMOHAPL_01250	7.07e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMOHAPL_01251	1.07e-306	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HIMOHAPL_01252	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMOHAPL_01253	9.18e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HIMOHAPL_01254	6.47e-64	-	-	-	-	-	-	-	-
HIMOHAPL_01255	2.8e-278	-	-	-	S	-	-	-	Membrane
HIMOHAPL_01256	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
HIMOHAPL_01257	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HIMOHAPL_01258	5.3e-78	-	-	-	-	-	-	-	-
HIMOHAPL_01259	5.71e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HIMOHAPL_01260	2.49e-63	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HIMOHAPL_01261	8.63e-58	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HIMOHAPL_01262	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HIMOHAPL_01263	7.66e-70	-	-	-	S	-	-	-	Putative adhesin
HIMOHAPL_01264	2.26e-173	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01265	9.39e-71	-	-	-	-	-	-	-	-
HIMOHAPL_01266	1.02e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HIMOHAPL_01267	1.11e-242	-	-	-	S	-	-	-	DUF218 domain
HIMOHAPL_01268	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01269	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HIMOHAPL_01270	5.9e-130	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HIMOHAPL_01271	4.84e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HIMOHAPL_01272	3.28e-257	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
HIMOHAPL_01273	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HIMOHAPL_01274	2.52e-261	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIMOHAPL_01275	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIMOHAPL_01276	4.38e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
HIMOHAPL_01277	6.36e-171	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIMOHAPL_01278	9.85e-154	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HIMOHAPL_01279	1.63e-163	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HIMOHAPL_01280	7.13e-89	-	-	-	-	-	-	-	-
HIMOHAPL_01281	8.93e-180	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HIMOHAPL_01282	6.82e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HIMOHAPL_01284	1.16e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01285	2.23e-77	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01286	5.77e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIMOHAPL_01287	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HIMOHAPL_01288	8.14e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HIMOHAPL_01289	3.7e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HIMOHAPL_01290	2.4e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HIMOHAPL_01291	4.23e-165	-	-	-	-	-	-	-	-
HIMOHAPL_01292	2.71e-260	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HIMOHAPL_01293	2.11e-290	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HIMOHAPL_01294	5.01e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01295	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01296	1.11e-177	-	-	-	-	-	-	-	-
HIMOHAPL_01297	3.41e-160	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIMOHAPL_01298	7.17e-233	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIMOHAPL_01299	9.7e-73	-	-	-	-	-	-	-	-
HIMOHAPL_01300	9.15e-165	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HIMOHAPL_01301	4.35e-198	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HIMOHAPL_01302	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HIMOHAPL_01303	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMOHAPL_01304	1.02e-231	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HIMOHAPL_01305	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMOHAPL_01306	5.61e-113	-	-	-	-	-	-	-	-
HIMOHAPL_01307	2.14e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HIMOHAPL_01308	2.16e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HIMOHAPL_01309	5.93e-167	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HIMOHAPL_01310	3.78e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HIMOHAPL_01311	1.41e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HIMOHAPL_01312	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01313	4.47e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01314	5.32e-183	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HIMOHAPL_01315	2.56e-201	-	-	-	L	-	-	-	HNH nucleases
HIMOHAPL_01316	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HIMOHAPL_01317	1.28e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HIMOHAPL_01318	1.13e-274	-	-	-	M	-	-	-	Glycosyl transferase
HIMOHAPL_01319	1.95e-10	-	-	-	-	-	-	-	-
HIMOHAPL_01320	6.1e-166	-	-	-	-	-	-	-	-
HIMOHAPL_01321	9.69e-25	-	-	-	-	-	-	-	-
HIMOHAPL_01322	4.17e-134	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HIMOHAPL_01323	2.47e-83	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMOHAPL_01324	1.12e-149	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HIMOHAPL_01325	1.59e-259	pbpX1	-	-	V	-	-	-	Beta-lactamase
HIMOHAPL_01326	2.29e-129	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HIMOHAPL_01327	1.31e-122	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HIMOHAPL_01328	1.13e-291	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HIMOHAPL_01329	3.45e-109	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_01330	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HIMOHAPL_01331	4.59e-241	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HIMOHAPL_01332	4.58e-85	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIMOHAPL_01333	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HIMOHAPL_01335	1.36e-302	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIMOHAPL_01336	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HIMOHAPL_01337	2.82e-300	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HIMOHAPL_01339	0.0	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01340	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
HIMOHAPL_01341	2.46e-211	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
HIMOHAPL_01342	2.6e-54	-	-	-	S	-	-	-	RloB-like protein
HIMOHAPL_01343	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HIMOHAPL_01344	4.64e-35	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HIMOHAPL_01345	4.3e-164	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HIMOHAPL_01346	4.2e-151	-	-	-	S	-	-	-	MTH538 TIR-like domain (DUF1863)
HIMOHAPL_01347	3.53e-100	-	-	-	-	-	-	-	-
HIMOHAPL_01348	4.28e-191	-	-	-	-	-	-	-	-
HIMOHAPL_01350	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HIMOHAPL_01351	1.17e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
HIMOHAPL_01352	2.62e-115	-	-	-	-	-	-	-	-
HIMOHAPL_01353	2.99e-95	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HIMOHAPL_01354	2.86e-102	-	-	-	S	-	-	-	HIRAN
HIMOHAPL_01355	2.45e-44	-	-	-	-	-	-	-	-
HIMOHAPL_01356	1.18e-229	-	-	-	-	-	-	-	-
HIMOHAPL_01357	6.79e-135	-	-	-	S	-	-	-	AAA domain
HIMOHAPL_01358	3.39e-32	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HIMOHAPL_01359	2.07e-60	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HIMOHAPL_01360	5.55e-80	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HIMOHAPL_01361	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
HIMOHAPL_01362	2.25e-37	-	-	-	-	-	-	-	-
HIMOHAPL_01363	1.13e-89	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HIMOHAPL_01364	1.12e-220	-	-	-	D	-	-	-	nuclear chromosome segregation
HIMOHAPL_01365	9.93e-196	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HIMOHAPL_01366	1.61e-70	-	-	-	-	-	-	-	-
HIMOHAPL_01367	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HIMOHAPL_01368	1.1e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIMOHAPL_01369	2.28e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HIMOHAPL_01370	3.39e-254	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HIMOHAPL_01371	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HIMOHAPL_01372	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HIMOHAPL_01373	2.06e-88	-	-	-	-	-	-	-	-
HIMOHAPL_01374	1.4e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HIMOHAPL_01375	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIMOHAPL_01376	6.14e-259	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HIMOHAPL_01377	3.03e-90	-	-	-	-	-	-	-	-
HIMOHAPL_01378	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
HIMOHAPL_01379	4.08e-270	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HIMOHAPL_01380	7.55e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
HIMOHAPL_01381	6.59e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HIMOHAPL_01382	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
HIMOHAPL_01383	2.45e-146	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIMOHAPL_01384	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HIMOHAPL_01385	1.11e-234	-	-	-	K	-	-	-	Transcriptional regulator
HIMOHAPL_01386	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMOHAPL_01387	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMOHAPL_01388	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIMOHAPL_01389	0.0	snf	-	-	KL	-	-	-	domain protein
HIMOHAPL_01390	6.65e-08	snf	-	-	KL	-	-	-	domain protein
HIMOHAPL_01391	1.49e-50	-	-	-	-	-	-	-	-
HIMOHAPL_01392	1.24e-08	-	-	-	-	-	-	-	-
HIMOHAPL_01393	1.19e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
HIMOHAPL_01394	1.51e-159	-	-	-	-	-	-	-	-
HIMOHAPL_01397	4.13e-83	-	-	-	-	-	-	-	-
HIMOHAPL_01398	2.41e-45	-	-	-	-	-	-	-	-
HIMOHAPL_01399	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HIMOHAPL_01400	9.67e-104	-	-	-	-	-	-	-	-
HIMOHAPL_01401	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HIMOHAPL_01402	5.87e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HIMOHAPL_01403	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIMOHAPL_01404	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HIMOHAPL_01405	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIMOHAPL_01406	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HIMOHAPL_01407	6.69e-149	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIMOHAPL_01408	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HIMOHAPL_01409	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HIMOHAPL_01410	1.66e-116	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HIMOHAPL_01411	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HIMOHAPL_01412	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HIMOHAPL_01413	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HIMOHAPL_01414	7.42e-174	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HIMOHAPL_01415	5.87e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HIMOHAPL_01416	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HIMOHAPL_01417	4.17e-237	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIMOHAPL_01418	5.22e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HIMOHAPL_01419	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HIMOHAPL_01420	2.54e-214	-	-	-	-	-	-	-	-
HIMOHAPL_01421	5.93e-186	-	-	-	-	-	-	-	-
HIMOHAPL_01422	1.49e-132	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HIMOHAPL_01423	4.24e-37	-	-	-	-	-	-	-	-
HIMOHAPL_01424	1.91e-193	-	-	-	-	-	-	-	-
HIMOHAPL_01425	1.26e-176	-	-	-	-	-	-	-	-
HIMOHAPL_01426	7.02e-182	-	-	-	-	-	-	-	-
HIMOHAPL_01427	3.8e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIMOHAPL_01428	2.17e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HIMOHAPL_01429	1.04e-309	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HIMOHAPL_01430	6.95e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIMOHAPL_01431	1.19e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HIMOHAPL_01432	5.37e-106	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HIMOHAPL_01433	3.06e-166	-	-	-	S	-	-	-	Peptidase family M23
HIMOHAPL_01434	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIMOHAPL_01435	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIMOHAPL_01436	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HIMOHAPL_01437	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HIMOHAPL_01438	7.41e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HIMOHAPL_01439	5.04e-279	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HIMOHAPL_01440	1.01e-256	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_01441	1.34e-34	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_01442	1.23e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIMOHAPL_01443	1.56e-70	-	-	-	-	ko:K19157	-	ko00000,ko01000,ko02048	-
HIMOHAPL_01444	7.26e-280	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
HIMOHAPL_01445	8.13e-268	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIMOHAPL_01446	1.64e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIMOHAPL_01447	9.58e-150	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HIMOHAPL_01448	1.74e-226	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIMOHAPL_01451	1.7e-13	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
HIMOHAPL_01452	5.99e-80	-	-	-	-	-	-	-	-
HIMOHAPL_01453	7.34e-65	-	-	-	-	-	-	-	-
HIMOHAPL_01454	2.63e-62	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_01455	9.22e-252	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HIMOHAPL_01456	3.34e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HIMOHAPL_01457	3.91e-248	ysdE	-	-	P	-	-	-	Citrate transporter
HIMOHAPL_01458	2.03e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HIMOHAPL_01459	1.41e-208	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HIMOHAPL_01460	1.97e-105	-	-	-	-	-	-	-	-
HIMOHAPL_01461	4.19e-100	-	-	-	M	-	-	-	LysM domain
HIMOHAPL_01462	3e-05	-	-	-	-	-	-	-	-
HIMOHAPL_01463	1.63e-112	-	-	-	-	-	-	-	-
HIMOHAPL_01464	6e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
HIMOHAPL_01465	3e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HIMOHAPL_01466	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01467	3.4e-114	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HIMOHAPL_01468	6.58e-225	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HIMOHAPL_01469	1.97e-134	-	-	-	G	-	-	-	Peptidase_C39 like family
HIMOHAPL_01470	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIMOHAPL_01471	2.87e-227	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HIMOHAPL_01472	1.45e-189	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HIMOHAPL_01473	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
HIMOHAPL_01474	0.0	yycH	-	-	S	-	-	-	YycH protein
HIMOHAPL_01475	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HIMOHAPL_01476	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HIMOHAPL_01478	4.46e-46	-	-	-	-	-	-	-	-
HIMOHAPL_01480	3.58e-193	-	-	-	I	-	-	-	Acyl-transferase
HIMOHAPL_01481	7.53e-203	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HIMOHAPL_01482	4.7e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
HIMOHAPL_01483	5.48e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
HIMOHAPL_01484	2.76e-215	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HIMOHAPL_01485	3.37e-50	-	-	-	S	-	-	-	Cytochrome B5
HIMOHAPL_01486	1.38e-107	-	-	-	J	-	-	-	FR47-like protein
HIMOHAPL_01487	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HIMOHAPL_01489	2.24e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIMOHAPL_01490	3.61e-60	-	-	-	-	-	-	-	-
HIMOHAPL_01491	2.77e-25	-	-	-	-	-	-	-	-
HIMOHAPL_01492	1.21e-40	-	-	-	-	-	-	-	-
HIMOHAPL_01493	2.56e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HIMOHAPL_01494	2.44e-198	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01495	2.47e-250	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HIMOHAPL_01496	4.33e-95	-	-	-	-	-	-	-	-
HIMOHAPL_01498	7.63e-112	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HIMOHAPL_01500	4.16e-194	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HIMOHAPL_01501	2.51e-196	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01502	6.7e-105	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HIMOHAPL_01503	1.74e-96	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HIMOHAPL_01504	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HIMOHAPL_01506	2.77e-129	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HIMOHAPL_01507	2.66e-57	-	-	-	L	-	-	-	transposase activity
HIMOHAPL_01508	4.92e-285	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIMOHAPL_01509	6.22e-267	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HIMOHAPL_01510	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HIMOHAPL_01511	2.71e-151	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIMOHAPL_01512	6.61e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HIMOHAPL_01513	8.33e-186	-	-	-	-	-	-	-	-
HIMOHAPL_01514	4.29e-175	-	-	-	-	-	-	-	-
HIMOHAPL_01515	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIMOHAPL_01516	1.81e-128	-	-	-	G	-	-	-	Aldose 1-epimerase
HIMOHAPL_01517	3.41e-257	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HIMOHAPL_01518	1.78e-146	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIMOHAPL_01519	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HIMOHAPL_01520	1.27e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIMOHAPL_01521	7.92e-97	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HIMOHAPL_01522	3.34e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HIMOHAPL_01526	2.71e-83	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01527	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01528	8.74e-315	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIMOHAPL_01529	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIMOHAPL_01530	4.23e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIMOHAPL_01531	9.37e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HIMOHAPL_01532	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HIMOHAPL_01533	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HIMOHAPL_01534	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HIMOHAPL_01535	1.5e-101	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HIMOHAPL_01536	1.58e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIMOHAPL_01537	6.36e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIMOHAPL_01538	7.48e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HIMOHAPL_01539	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIMOHAPL_01540	2.61e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HIMOHAPL_01541	2.84e-35	-	-	-	-	-	-	-	-
HIMOHAPL_01542	5.88e-167	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01543	1.77e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIMOHAPL_01544	1.82e-290	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HIMOHAPL_01545	1.36e-260	pbpX	-	-	V	-	-	-	Beta-lactamase
HIMOHAPL_01546	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HIMOHAPL_01547	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HIMOHAPL_01548	2.08e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HIMOHAPL_01550	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
HIMOHAPL_01551	9.62e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMOHAPL_01552	1.15e-194	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
HIMOHAPL_01553	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HIMOHAPL_01554	1.3e-202	yvgN	-	-	C	-	-	-	Aldo keto reductase
HIMOHAPL_01555	1.17e-191	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HIMOHAPL_01556	2.41e-173	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HIMOHAPL_01557	1.66e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HIMOHAPL_01558	6.76e-168	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIMOHAPL_01559	1.74e-175	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01560	4.08e-26	-	-	-	-	-	-	-	-
HIMOHAPL_01561	2.9e-71	-	-	-	-	-	-	-	-
HIMOHAPL_01562	1.48e-259	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HIMOHAPL_01563	8.27e-52	-	-	-	C	-	-	-	Flavodoxin
HIMOHAPL_01564	6.5e-191	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HIMOHAPL_01565	1.32e-68	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIMOHAPL_01566	1.47e-244	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HIMOHAPL_01567	1.6e-204	-	-	-	M	-	-	-	Peptidase family M1 domain
HIMOHAPL_01568	1.36e-139	-	-	-	M	-	-	-	Peptidase family M1 domain
HIMOHAPL_01569	1.39e-145	-	-	-	L	-	-	-	Resolvase, N-terminal
HIMOHAPL_01570	2.42e-283	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HIMOHAPL_01571	5.59e-224	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01572	2.84e-300	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HIMOHAPL_01573	9.51e-316	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HIMOHAPL_01574	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMOHAPL_01575	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
HIMOHAPL_01577	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIMOHAPL_01578	6.65e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HIMOHAPL_01579	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01580	1.61e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HIMOHAPL_01581	1.7e-41	-	-	-	-	-	-	-	-
HIMOHAPL_01582	9.98e-193	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIMOHAPL_01583	8.15e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HIMOHAPL_01584	0.0	-	-	-	-	-	-	-	-
HIMOHAPL_01585	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HIMOHAPL_01587	6.44e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HIMOHAPL_01588	0.0	yhaN	-	-	L	-	-	-	AAA domain
HIMOHAPL_01589	8.69e-298	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HIMOHAPL_01590	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HIMOHAPL_01591	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HIMOHAPL_01592	2.09e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HIMOHAPL_01593	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HIMOHAPL_01594	6.73e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HIMOHAPL_01595	2.23e-181	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HIMOHAPL_01596	6.98e-96	ptcC	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_01597	1.03e-197	ptcC	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_01598	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HIMOHAPL_01599	1.16e-72	-	-	-	-	-	-	-	-
HIMOHAPL_01600	1.23e-189	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HIMOHAPL_01601	1.71e-197	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HIMOHAPL_01602	1.15e-159	mdcG	2.7.7.66	-	H	ko:K13934	-	ko00000,ko01000	Phosphoribosyl-dephospho-CoA transferase MdcG
HIMOHAPL_01603	0.0	mdcD	4.1.1.87	-	I	ko:K13932	-	ko00000,ko01000	Malonate decarboxylase gamma subunit (MdcE)
HIMOHAPL_01604	1.84e-68	mdcC	-	-	C	ko:K13931	-	ko00000,ko02000	Malonate decarboxylase delta subunit (MdcD)
HIMOHAPL_01605	0.0	mdcA	2.3.1.187	-	I	ko:K13929	-	ko00000,ko01000,ko02000	Malonate decarboxylase, alpha subunit, transporter
HIMOHAPL_01606	4.78e-218	mdcH	2.3.1.39	-	I	ko:K13935	-	ko00000,ko01000	Acyl transferase domain
HIMOHAPL_01607	1.77e-205	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HIMOHAPL_01608	1.5e-282	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HIMOHAPL_01609	2.63e-211	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMOHAPL_01610	4.08e-109	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HIMOHAPL_01611	2.84e-263	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HIMOHAPL_01612	2.12e-299	-	-	-	L	-	-	-	Transposase
HIMOHAPL_01613	2.98e-59	-	-	-	-	-	-	-	-
HIMOHAPL_01614	6.35e-51	-	-	-	-	-	-	-	-
HIMOHAPL_01615	1.57e-119	-	-	-	L	-	-	-	NUDIX domain
HIMOHAPL_01616	4.24e-217	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HIMOHAPL_01617	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HIMOHAPL_01618	4.81e-130	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HIMOHAPL_01619	5.47e-198	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIMOHAPL_01620	1.01e-308	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HIMOHAPL_01622	2.97e-64	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HIMOHAPL_01623	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HIMOHAPL_01624	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HIMOHAPL_01625	3.42e-157	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HIMOHAPL_01626	1.36e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HIMOHAPL_01627	1.99e-122	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HIMOHAPL_01628	8.64e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HIMOHAPL_01629	1.77e-207	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HIMOHAPL_01630	8.31e-228	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HIMOHAPL_01631	8.35e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIMOHAPL_01632	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HIMOHAPL_01633	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HIMOHAPL_01634	1.03e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HIMOHAPL_01635	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HIMOHAPL_01636	1.04e-189	-	-	-	K	-	-	-	rpiR family
HIMOHAPL_01637	1.01e-252	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HIMOHAPL_01638	3.02e-199	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HIMOHAPL_01639	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HIMOHAPL_01640	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HIMOHAPL_01641	8.87e-288	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIMOHAPL_01644	2.45e-212	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HIMOHAPL_01647	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HIMOHAPL_01648	6.29e-82	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HIMOHAPL_01649	1.59e-131	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HIMOHAPL_01650	5.16e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIMOHAPL_01651	1.01e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HIMOHAPL_01652	1.13e-126	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HIMOHAPL_01653	6.72e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_01654	2.58e-186	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_01655	1.02e-137	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HIMOHAPL_01656	5.41e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01657	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HIMOHAPL_01658	1.51e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HIMOHAPL_01659	7.53e-163	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HIMOHAPL_01660	5.59e-310	-	-	-	S	-	-	-	response to antibiotic
HIMOHAPL_01661	5.45e-162	-	-	-	-	-	-	-	-
HIMOHAPL_01662	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HIMOHAPL_01663	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HIMOHAPL_01664	7.25e-57	-	-	-	-	-	-	-	-
HIMOHAPL_01665	6.6e-14	-	-	-	-	-	-	-	-
HIMOHAPL_01666	1.35e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HIMOHAPL_01667	8.28e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HIMOHAPL_01668	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HIMOHAPL_01669	1.69e-194	-	-	-	-	-	-	-	-
HIMOHAPL_01670	3.32e-13	-	-	-	-	-	-	-	-
HIMOHAPL_01671	2.22e-120	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HIMOHAPL_01672	2.57e-193	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HIMOHAPL_01673	4.99e-136	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HIMOHAPL_01675	1.5e-37	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HIMOHAPL_01676	4.48e-47	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HIMOHAPL_01677	1.07e-18	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HIMOHAPL_01678	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HIMOHAPL_01679	1.15e-54	-	-	-	D	-	-	-	YSIRK type signal peptide
HIMOHAPL_01680	7.15e-199	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HIMOHAPL_01681	2.49e-08	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HIMOHAPL_01682	1.11e-169	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
HIMOHAPL_01683	4.81e-253	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HIMOHAPL_01684	1.6e-79	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HIMOHAPL_01685	6.77e-39	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HIMOHAPL_01686	1.98e-74	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01688	1.82e-05	-	-	-	-	-	-	-	-
HIMOHAPL_01689	8.38e-176	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01690	4.48e-258	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HIMOHAPL_01691	4.05e-163	-	-	-	S	ko:K19310	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HIMOHAPL_01692	1.73e-217	-	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIMOHAPL_01693	2.93e-136	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
HIMOHAPL_01694	4.82e-41	-	-	-	S	-	-	-	Filamentation induced by cAMP protein fic
HIMOHAPL_01695	6.56e-76	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HIMOHAPL_01696	3.18e-202	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HIMOHAPL_01697	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HIMOHAPL_01698	2.55e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIMOHAPL_01699	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMOHAPL_01700	1.68e-253	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIMOHAPL_01701	9.94e-209	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_01702	3.26e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01703	5.01e-151	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01704	3.26e-142	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HIMOHAPL_01706	3.71e-76	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HIMOHAPL_01707	1.01e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMOHAPL_01708	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HIMOHAPL_01709	2.72e-213	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMOHAPL_01710	1.46e-95	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HIMOHAPL_01711	2.42e-69	-	-	-	S	-	-	-	Abi-like protein
HIMOHAPL_01712	1.46e-283	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01713	2.71e-62	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HIMOHAPL_01714	1.16e-23	-	-	-	-	-	-	-	-
HIMOHAPL_01715	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HIMOHAPL_01716	3.52e-163	csrR	-	-	K	-	-	-	response regulator
HIMOHAPL_01717	5.37e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HIMOHAPL_01718	1.39e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HIMOHAPL_01719	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIMOHAPL_01720	9.22e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HIMOHAPL_01721	8.77e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIMOHAPL_01722	5.03e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HIMOHAPL_01723	6.85e-109	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HIMOHAPL_01724	3.01e-255	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HIMOHAPL_01725	3.21e-195	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HIMOHAPL_01726	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIMOHAPL_01727	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HIMOHAPL_01728	1.07e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIMOHAPL_01729	1.14e-63	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_01730	9.37e-144	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
HIMOHAPL_01731	1.99e-104	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HIMOHAPL_01732	1.34e-61	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HIMOHAPL_01733	6.3e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HIMOHAPL_01734	5.39e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
HIMOHAPL_01735	6.94e-44	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HIMOHAPL_01736	3.85e-299	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HIMOHAPL_01737	3.9e-126	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIMOHAPL_01738	3.74e-125	-	-	-	-	-	-	-	-
HIMOHAPL_01739	2.31e-53	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
HIMOHAPL_01740	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
HIMOHAPL_01741	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HIMOHAPL_01742	2.79e-142	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HIMOHAPL_01743	1.68e-77	-	-	-	-	-	-	-	-
HIMOHAPL_01744	5.87e-99	-	-	-	-	-	-	-	-
HIMOHAPL_01745	1.66e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HIMOHAPL_01746	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01747	7.42e-123	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIMOHAPL_01748	7.44e-191	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_01749	1.19e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01750	4.52e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
HIMOHAPL_01751	1.52e-39	-	-	-	S	-	-	-	Motility quorum-sensing regulator, toxin of MqsA
HIMOHAPL_01752	5.21e-70	-	-	-	K	-	-	-	sequence-specific DNA binding
HIMOHAPL_01753	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HIMOHAPL_01754	1.79e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HIMOHAPL_01755	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HIMOHAPL_01756	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HIMOHAPL_01757	2.53e-106	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HIMOHAPL_01758	5.02e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIMOHAPL_01759	6.43e-167	-	-	-	F	-	-	-	glutamine amidotransferase
HIMOHAPL_01760	8.02e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HIMOHAPL_01761	9.3e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HIMOHAPL_01762	6.41e-194	-	-	-	-	-	-	-	-
HIMOHAPL_01763	1.74e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
HIMOHAPL_01764	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HIMOHAPL_01765	1.07e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HIMOHAPL_01766	5.34e-134	-	-	-	-	-	-	-	-
HIMOHAPL_01767	2.7e-172	-	-	-	-	-	-	-	-
HIMOHAPL_01768	1.09e-272	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HIMOHAPL_01769	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HIMOHAPL_01770	6.04e-49	-	-	-	-	-	-	-	-
HIMOHAPL_01772	6.94e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HIMOHAPL_01773	4.6e-113	-	-	-	K	-	-	-	GNAT family
HIMOHAPL_01774	2.93e-70	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HIMOHAPL_01775	3.43e-168	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HIMOHAPL_01776	9.36e-188	-	-	-	EGP	-	-	-	Major Facilitator
HIMOHAPL_01777	8.27e-45	-	-	-	K	-	-	-	Transcriptional regulator
HIMOHAPL_01779	8.06e-07	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HIMOHAPL_01781	5.16e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIMOHAPL_01782	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
HIMOHAPL_01783	4.01e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HIMOHAPL_01784	6.47e-155	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HIMOHAPL_01785	1.32e-99	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HIMOHAPL_01786	4e-107	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HIMOHAPL_01787	2.02e-152	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HIMOHAPL_01788	1.58e-257	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIMOHAPL_01789	9.18e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HIMOHAPL_01790	4.58e-291	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HIMOHAPL_01791	1.15e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HIMOHAPL_01792	2.89e-168	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HIMOHAPL_01793	5.66e-16	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HIMOHAPL_01794	2.97e-124	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HIMOHAPL_01795	2.32e-259	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HIMOHAPL_01796	6.59e-315	-	-	-	M	-	-	-	Glycosyl transferase
HIMOHAPL_01798	9e-193	-	-	-	-	-	-	-	-
HIMOHAPL_01799	1.72e-80	-	-	-	M	-	-	-	Peptidase family M1 domain
HIMOHAPL_01800	4.86e-33	-	-	-	-	-	-	-	-
HIMOHAPL_01801	2.33e-83	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HIMOHAPL_01802	5.51e-46	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
HIMOHAPL_01803	2.52e-65	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HIMOHAPL_01805	9.67e-33	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HIMOHAPL_01806	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIMOHAPL_01807	2.16e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIMOHAPL_01808	2.07e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIMOHAPL_01809	3.7e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIMOHAPL_01810	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HIMOHAPL_01811	5.35e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HIMOHAPL_01812	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIMOHAPL_01813	2.89e-111	-	-	-	-	-	-	-	-
HIMOHAPL_01814	8.4e-255	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
HIMOHAPL_01815	9.72e-79	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HIMOHAPL_01816	1.11e-91	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HIMOHAPL_01817	1.32e-49	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIMOHAPL_01818	3.55e-48	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIMOHAPL_01819	3.9e-49	ydhF	-	-	S	-	-	-	Aldo keto reductase
HIMOHAPL_01820	9.49e-161	-	4.2.1.156, 4.2.1.42, 4.2.1.68	-	M	ko:K18334,ko:K20023	ko00051,ko00053,ko01120,map00051,map00053,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HIMOHAPL_01821	3.66e-110	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HIMOHAPL_01822	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HIMOHAPL_01823	3.86e-300	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HIMOHAPL_01824	5.22e-11	-	-	-	S	-	-	-	oxidoreductase activity
HIMOHAPL_01825	1.02e-122	-	-	-	S	-	-	-	oxidoreductase activity
HIMOHAPL_01826	2.34e-229	-	-	-	L	-	-	-	Transposase
HIMOHAPL_01827	4.52e-152	-	-	-	L	-	-	-	Transposase
HIMOHAPL_01828	1.27e-70	-	-	-	L	-	-	-	Transposase
HIMOHAPL_01829	2.08e-96	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HIMOHAPL_01830	8.06e-201	-	-	-	K	-	-	-	Transcriptional regulator
HIMOHAPL_01831	3.22e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HIMOHAPL_01832	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HIMOHAPL_01833	9.65e-181	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HIMOHAPL_01834	1.57e-235	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HIMOHAPL_01835	0.000104	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HIMOHAPL_01837	7.16e-116	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIMOHAPL_01838	1.66e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HIMOHAPL_01839	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HIMOHAPL_01840	8.97e-47	-	-	-	-	-	-	-	-
HIMOHAPL_01841	3.07e-202	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HIMOHAPL_01842	5.79e-62	-	-	-	-	-	-	-	-
HIMOHAPL_01843	8.57e-259	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HIMOHAPL_01844	3.06e-121	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIMOHAPL_01845	6.13e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_01846	6.02e-27	-	-	-	E	-	-	-	Pfam:DUF955
HIMOHAPL_01847	8.25e-16	-	-	-	S	-	-	-	Protein conserved in bacteria
HIMOHAPL_01849	4.46e-84	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HIMOHAPL_01850	3.72e-145	-	-	-	L	-	-	-	Resolvase, N terminal domain
HIMOHAPL_01851	0.0	-	-	-	L	-	-	-	Probable transposase
HIMOHAPL_01852	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIMOHAPL_01853	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HIMOHAPL_01854	4.55e-93	-	-	-	-	-	-	-	-
HIMOHAPL_01855	1.42e-29	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
HIMOHAPL_01856	3.77e-92	-	-	-	K	-	-	-	sequence-specific DNA binding
HIMOHAPL_01857	3.29e-52	-	-	-	S	-	-	-	SnoaL-like domain
HIMOHAPL_01858	0.0	-	-	-	L	-	-	-	PLD-like domain
HIMOHAPL_01859	2.29e-131	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
HIMOHAPL_01860	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HIMOHAPL_01861	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HIMOHAPL_01862	6.95e-282	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HIMOHAPL_01863	3.72e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIMOHAPL_01864	7.77e-151	-	-	-	-	-	-	-	-
HIMOHAPL_01865	1.35e-203	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMOHAPL_01866	8.08e-97	-	-	-	-	-	-	-	-
HIMOHAPL_01867	3.66e-138	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIMOHAPL_01868	1.71e-150	-	-	-	S	-	-	-	Peptidase family M23
HIMOHAPL_01869	1.09e-133	-	-	-	-	-	-	-	-
HIMOHAPL_01870	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HIMOHAPL_01871	9.51e-47	-	-	-	C	-	-	-	Heavy-metal-associated domain
HIMOHAPL_01872	6.86e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HIMOHAPL_01873	9.29e-61	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HIMOHAPL_01874	2.15e-59	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HIMOHAPL_01876	1.72e-62	-	-	-	-	-	-	-	-
HIMOHAPL_01877	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
HIMOHAPL_01878	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
HIMOHAPL_01879	1.85e-142	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
HIMOHAPL_01880	3.54e-256	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
HIMOHAPL_01881	5.23e-171	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HIMOHAPL_01882	5.71e-159	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
HIMOHAPL_01883	1.17e-220	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HIMOHAPL_01884	1.79e-211	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
HIMOHAPL_01885	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HIMOHAPL_01886	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HIMOHAPL_01887	3.75e-93	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HIMOHAPL_01888	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HIMOHAPL_01889	2.94e-128	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIMOHAPL_01890	1.37e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIMOHAPL_01891	7.37e-261	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HIMOHAPL_01892	9.95e-30	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_01893	6.32e-214	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HIMOHAPL_01895	1.23e-42	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HIMOHAPL_01896	1.45e-16	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HIMOHAPL_01897	4.41e-05	-	-	-	S	-	-	-	Metal binding domain of Ada
HIMOHAPL_01898	1.21e-12	-	-	-	S	-	-	-	Metal binding domain of Ada
HIMOHAPL_01899	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HIMOHAPL_01900	1.5e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HIMOHAPL_01901	6.15e-300	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HIMOHAPL_01902	2.63e-84	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIMOHAPL_01903	5.24e-61	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIMOHAPL_01904	2.55e-139	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HIMOHAPL_01905	9.06e-125	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HIMOHAPL_01906	3.59e-286	-	-	-	S	-	-	-	Sterol carrier protein domain
HIMOHAPL_01907	4.04e-29	-	-	-	-	-	-	-	-
HIMOHAPL_01908	1.03e-141	-	-	-	K	-	-	-	LysR substrate binding domain
HIMOHAPL_01909	1.13e-126	-	-	-	-	-	-	-	-
HIMOHAPL_01910	1.39e-151	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HIMOHAPL_01911	3.23e-159	-	-	-	-	-	-	-	-
HIMOHAPL_01912	9.82e-306	-	-	-	M	-	-	-	Rib/alpha-like repeat
HIMOHAPL_01913	1.22e-310	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HIMOHAPL_01914	1.58e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIMOHAPL_01915	1.61e-250	potE	-	-	E	-	-	-	Amino Acid
HIMOHAPL_01916	5.19e-90	potE	-	-	E	-	-	-	Amino Acid
HIMOHAPL_01917	2.09e-247	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01918	2.08e-122	-	-	-	S	-	-	-	SLAP domain
HIMOHAPL_01919	2.71e-177	-	-	-	S	-	-	-	Fic/DOC family
HIMOHAPL_01920	0.0	-	-	-	-	-	-	-	-
HIMOHAPL_01921	5.06e-111	-	-	-	-	-	-	-	-
HIMOHAPL_01922	4.05e-124	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HIMOHAPL_01923	2.26e-90	-	-	-	O	-	-	-	OsmC-like protein
HIMOHAPL_01924	9.57e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIMOHAPL_01925	1.07e-299	sptS	-	-	T	-	-	-	Histidine kinase
HIMOHAPL_01926	1.48e-30	dltr	-	-	K	-	-	-	response regulator
HIMOHAPL_01927	3.13e-185	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HIMOHAPL_01928	1.31e-83	-	-	-	L	-	-	-	Resolvase, N-terminal
HIMOHAPL_01929	1.86e-94	dltr	-	-	K	-	-	-	response regulator
HIMOHAPL_01930	2.96e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HIMOHAPL_01931	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HIMOHAPL_01932	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HIMOHAPL_01933	1.72e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIMOHAPL_01934	8.75e-197	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIMOHAPL_01935	1.98e-200	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIMOHAPL_01936	1.16e-304	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIMOHAPL_01937	3.79e-223	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
HIMOHAPL_01938	2.14e-48	-	-	-	-	-	-	-	-
HIMOHAPL_01939	1.87e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HIMOHAPL_01940	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HIMOHAPL_01941	1.45e-280	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIMOHAPL_01942	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HIMOHAPL_01943	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HIMOHAPL_01944	4.02e-238	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HIMOHAPL_01945	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HIMOHAPL_01946	5.29e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HIMOHAPL_01947	4.04e-240	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HIMOHAPL_01948	4.43e-163	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HIMOHAPL_01949	1.61e-34	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HIMOHAPL_01950	4.56e-136	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HIMOHAPL_01951	1.68e-191	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HIMOHAPL_01979	1.41e-285	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HIMOHAPL_01980	9.03e-257	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HIMOHAPL_01981	8.57e-227	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIMOHAPL_01982	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HIMOHAPL_01983	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HIMOHAPL_01984	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIMOHAPL_01985	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIMOHAPL_01986	3.33e-24	-	-	-	M	-	-	-	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
HIMOHAPL_01987	8.64e-86	-	-	-	EG	-	-	-	GntP family permease
HIMOHAPL_01988	3.82e-165	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HIMOHAPL_01989	0.0	-	-	-	L	-	-	-	Transposase
HIMOHAPL_01990	3.45e-302	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HIMOHAPL_01991	1.99e-99	yybA	-	-	K	-	-	-	Transcriptional regulator
HIMOHAPL_01992	4.7e-125	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HIMOHAPL_01993	2.3e-128	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HIMOHAPL_01994	7.04e-115	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HIMOHAPL_01995	9.36e-317	-	-	-	T	-	-	-	GHKL domain
HIMOHAPL_01996	4.48e-171	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HIMOHAPL_01997	1.28e-228	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HIMOHAPL_01998	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HIMOHAPL_01999	5.69e-182	-	-	-	S	-	-	-	PAS domain
HIMOHAPL_02001	2.82e-182	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HIMOHAPL_02002	7.53e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HIMOHAPL_02003	2.23e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HIMOHAPL_02004	8.83e-204	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HIMOHAPL_02005	1.1e-231	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HIMOHAPL_02006	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HIMOHAPL_02007	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HIMOHAPL_02008	5.26e-259	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIMOHAPL_02009	4.02e-203	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HIMOHAPL_02010	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIMOHAPL_02011	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HIMOHAPL_02012	6.07e-310	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIMOHAPL_02013	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HIMOHAPL_02014	5.41e-205	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HIMOHAPL_02015	3.76e-128	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIMOHAPL_02016	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HIMOHAPL_02018	2.63e-31	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIMOHAPL_02019	4.89e-220	-	-	-	-	-	-	-	-
HIMOHAPL_02020	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HIMOHAPL_02021	1.21e-119	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HIMOHAPL_02022	8.45e-204	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HIMOHAPL_02023	3.19e-197	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HIMOHAPL_02024	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
HIMOHAPL_02025	2.04e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HIMOHAPL_02026	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIMOHAPL_02027	4.69e-117	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIMOHAPL_02028	5e-53	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIMOHAPL_02029	1.58e-185	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIMOHAPL_02030	7.03e-211	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HIMOHAPL_02031	1.71e-198	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_02032	2.89e-46	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_02033	1.94e-119	-	-	-	-	-	-	-	-
HIMOHAPL_02034	2.42e-22	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HIMOHAPL_02035	5.71e-58	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HIMOHAPL_02036	2.62e-194	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HIMOHAPL_02037	1.87e-117	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HIMOHAPL_02038	7.27e-75	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HIMOHAPL_02039	7.19e-101	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HIMOHAPL_02040	4.67e-146	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HIMOHAPL_02041	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HIMOHAPL_02042	6.47e-213	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HIMOHAPL_02043	2.86e-289	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HIMOHAPL_02044	2.08e-145	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HIMOHAPL_02045	3.47e-243	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HIMOHAPL_02046	2.21e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HIMOHAPL_02047	4.33e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIMOHAPL_02048	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HIMOHAPL_02049	1.22e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIMOHAPL_02050	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIMOHAPL_02051	2.88e-183	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HIMOHAPL_02052	2.59e-253	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HIMOHAPL_02053	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIMOHAPL_02054	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMOHAPL_02055	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HIMOHAPL_02056	1.02e-260	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HIMOHAPL_02057	3.75e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HIMOHAPL_02058	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
HIMOHAPL_02059	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIMOHAPL_02060	2.88e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIMOHAPL_02061	4.2e-201	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIMOHAPL_02062	1.6e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HIMOHAPL_02063	2.56e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIMOHAPL_02064	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIMOHAPL_02065	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HIMOHAPL_02066	5.88e-278	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIMOHAPL_02067	9.16e-105	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HIMOHAPL_02068	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIMOHAPL_02069	1.66e-143	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HIMOHAPL_02070	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HIMOHAPL_02071	1.2e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIMOHAPL_02072	3.31e-109	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HIMOHAPL_02074	4.78e-255	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HIMOHAPL_02075	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HIMOHAPL_02076	9.17e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HIMOHAPL_02077	9.85e-147	-	-	-	I	-	-	-	Acid phosphatase homologues