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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MAKDMGGG_00001	3.37e-184	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MAKDMGGG_00002	7.69e-45	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MAKDMGGG_00009	2.65e-48	-	-	-	LM	-	-	-	gp58-like protein
MAKDMGGG_00010	1.95e-272	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MAKDMGGG_00011	1.99e-198	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MAKDMGGG_00012	1.72e-218	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
MAKDMGGG_00013	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MAKDMGGG_00014	4.92e-105	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
MAKDMGGG_00016	0.000319	-	-	-	-	-	-	-	-
MAKDMGGG_00017	8.59e-95	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MAKDMGGG_00018	1.53e-256	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MAKDMGGG_00019	4e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAKDMGGG_00020	1.56e-79	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MAKDMGGG_00021	4.55e-16	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MAKDMGGG_00022	1.66e-58	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00023	2.55e-19	-	-	-	CP	-	-	-	ABC-2 family transporter protein
MAKDMGGG_00024	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MAKDMGGG_00025	9.02e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MAKDMGGG_00026	5.91e-23	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MAKDMGGG_00027	1.51e-148	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MAKDMGGG_00028	1.83e-72	-	-	-	-	-	-	-	-
MAKDMGGG_00029	9.21e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MAKDMGGG_00030	1.7e-26	-	-	-	-	-	-	-	-
MAKDMGGG_00031	1.75e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MAKDMGGG_00032	9.72e-156	csrR	-	-	K	-	-	-	response regulator
MAKDMGGG_00033	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKDMGGG_00034	0.0	potE	-	-	E	-	-	-	Amino Acid
MAKDMGGG_00035	1.74e-291	-	-	-	V	-	-	-	MatE
MAKDMGGG_00036	3.32e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MAKDMGGG_00037	1.77e-211	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAKDMGGG_00038	2.45e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MAKDMGGG_00039	2.71e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAKDMGGG_00040	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKDMGGG_00041	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAKDMGGG_00042	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MAKDMGGG_00043	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAKDMGGG_00044	5.46e-145	-	-	-	M	-	-	-	PFAM NLP P60 protein
MAKDMGGG_00045	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MAKDMGGG_00046	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAKDMGGG_00047	9.37e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MAKDMGGG_00048	0.0	-	-	-	S	-	-	-	membrane
MAKDMGGG_00049	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAKDMGGG_00050	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MAKDMGGG_00051	6.32e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MAKDMGGG_00052	1.13e-145	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
MAKDMGGG_00053	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MAKDMGGG_00054	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MAKDMGGG_00055	2.25e-92	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MAKDMGGG_00056	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MAKDMGGG_00057	4.12e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MAKDMGGG_00058	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MAKDMGGG_00059	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MAKDMGGG_00060	1.7e-282	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKDMGGG_00061	1.28e-18	-	-	-	-	-	-	-	-
MAKDMGGG_00062	1.39e-196	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAKDMGGG_00063	9.48e-130	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MAKDMGGG_00064	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
MAKDMGGG_00065	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
MAKDMGGG_00066	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MAKDMGGG_00067	4.06e-93	-	-	-	-	-	-	-	-
MAKDMGGG_00068	5.2e-139	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
MAKDMGGG_00069	1.58e-314	-	-	-	E	-	-	-	amino acid
MAKDMGGG_00070	8.02e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MAKDMGGG_00072	4.65e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MAKDMGGG_00073	1.47e-120	-	-	-	-	-	-	-	-
MAKDMGGG_00074	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MAKDMGGG_00075	4.32e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAKDMGGG_00076	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MAKDMGGG_00077	6.51e-114	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MAKDMGGG_00078	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MAKDMGGG_00079	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
MAKDMGGG_00080	1.8e-215	-	-	-	C	-	-	-	Aldo keto reductase
MAKDMGGG_00081	3.7e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MAKDMGGG_00082	1.28e-65	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MAKDMGGG_00083	4.02e-242	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MAKDMGGG_00084	4.2e-18	sptS	-	-	T	-	-	-	Histidine kinase
MAKDMGGG_00085	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MAKDMGGG_00086	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MAKDMGGG_00087	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MAKDMGGG_00088	1.3e-262	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MAKDMGGG_00089	8.02e-202	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MAKDMGGG_00090	1.32e-55	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MAKDMGGG_00091	2.13e-311	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
MAKDMGGG_00092	1.37e-194	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MAKDMGGG_00093	2.3e-69	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MAKDMGGG_00094	6.78e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
MAKDMGGG_00095	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
MAKDMGGG_00096	5.01e-68	entB	-	-	Q	-	-	-	Isochorismatase family
MAKDMGGG_00097	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MAKDMGGG_00098	2.53e-240	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MAKDMGGG_00099	3.1e-216	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MAKDMGGG_00100	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MAKDMGGG_00101	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAKDMGGG_00102	1.2e-161	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAKDMGGG_00103	1.85e-113	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MAKDMGGG_00104	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
MAKDMGGG_00105	1.23e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MAKDMGGG_00106	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
MAKDMGGG_00107	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MAKDMGGG_00108	5.62e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MAKDMGGG_00109	3.84e-145	-	-	-	S	-	-	-	(CBS) domain
MAKDMGGG_00110	1.14e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
MAKDMGGG_00111	1.25e-305	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
MAKDMGGG_00112	1.33e-261	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MAKDMGGG_00113	2.04e-30	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MAKDMGGG_00114	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MAKDMGGG_00115	7.62e-270	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MAKDMGGG_00116	1.61e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MAKDMGGG_00117	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MAKDMGGG_00118	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAKDMGGG_00119	6.38e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MAKDMGGG_00120	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MAKDMGGG_00121	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MAKDMGGG_00122	5.99e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MAKDMGGG_00123	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
MAKDMGGG_00124	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MAKDMGGG_00125	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MAKDMGGG_00126	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MAKDMGGG_00127	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MAKDMGGG_00128	6.66e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MAKDMGGG_00129	1.45e-152	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MAKDMGGG_00130	9.19e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MAKDMGGG_00131	5.83e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAKDMGGG_00132	1.01e-160	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MAKDMGGG_00133	6.49e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAKDMGGG_00134	6.48e-303	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MAKDMGGG_00135	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MAKDMGGG_00136	2.62e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAKDMGGG_00137	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MAKDMGGG_00138	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MAKDMGGG_00139	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MAKDMGGG_00140	1.13e-186	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
MAKDMGGG_00141	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
MAKDMGGG_00142	4.65e-190	yidA	-	-	S	-	-	-	hydrolase
MAKDMGGG_00143	6.01e-101	-	-	-	-	-	-	-	-
MAKDMGGG_00144	9.36e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAKDMGGG_00145	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MAKDMGGG_00146	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MAKDMGGG_00147	5.86e-164	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MAKDMGGG_00148	9.8e-158	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MAKDMGGG_00149	2.02e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MAKDMGGG_00150	2.44e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MAKDMGGG_00151	8.99e-104	-	-	-	-	-	-	-	-
MAKDMGGG_00152	6.56e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MAKDMGGG_00153	9.79e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKDMGGG_00155	5.78e-42	-	-	-	-	-	-	-	-
MAKDMGGG_00156	1.88e-79	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MAKDMGGG_00157	2.41e-98	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MAKDMGGG_00158	2.22e-40	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MAKDMGGG_00159	2.47e-207	-	-	-	C	-	-	-	Oxidoreductase
MAKDMGGG_00161	1.07e-96	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Psort location Cytoplasmic, score 8.87
MAKDMGGG_00163	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MAKDMGGG_00164	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MAKDMGGG_00165	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MAKDMGGG_00166	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MAKDMGGG_00167	1.33e-240	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MAKDMGGG_00168	1.54e-56	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MAKDMGGG_00169	3.87e-73	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MAKDMGGG_00170	7.05e-56	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MAKDMGGG_00171	7.47e-152	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MAKDMGGG_00172	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
MAKDMGGG_00173	2.23e-96	-	-	-	L	-	-	-	nuclease
MAKDMGGG_00174	4.29e-179	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MAKDMGGG_00175	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
MAKDMGGG_00176	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MAKDMGGG_00177	1.75e-29	-	-	-	-	-	-	-	-
MAKDMGGG_00178	3.09e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MAKDMGGG_00179	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MAKDMGGG_00180	6.49e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MAKDMGGG_00181	4.57e-36	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
MAKDMGGG_00182	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAKDMGGG_00183	4.69e-200	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MAKDMGGG_00184	1.68e-200	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAKDMGGG_00185	1.37e-92	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAKDMGGG_00187	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MAKDMGGG_00188	8.97e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MAKDMGGG_00189	6.83e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
MAKDMGGG_00190	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MAKDMGGG_00191	5.16e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKDMGGG_00192	1.15e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKDMGGG_00193	2.68e-87	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MAKDMGGG_00194	7.61e-181	-	-	-	S	-	-	-	DUF218 domain
MAKDMGGG_00195	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
MAKDMGGG_00196	7.52e-53	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MAKDMGGG_00197	9.78e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
MAKDMGGG_00199	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MAKDMGGG_00200	7.21e-87	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MAKDMGGG_00201	2.67e-66	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
MAKDMGGG_00202	2.43e-158	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAKDMGGG_00203	1.38e-186	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MAKDMGGG_00205	4.2e-88	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
MAKDMGGG_00206	1.95e-51	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
MAKDMGGG_00208	6.14e-193	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
MAKDMGGG_00209	2.67e-116	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MAKDMGGG_00210	1.36e-11	-	-	-	K	-	-	-	Helix-turn-helix domain
MAKDMGGG_00211	8.21e-65	-	-	-	-	-	-	-	-
MAKDMGGG_00212	3.68e-68	-	-	-	-	-	-	-	-
MAKDMGGG_00213	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAKDMGGG_00214	1.07e-42	-	-	-	-	-	-	-	-
MAKDMGGG_00215	3.99e-76	-	-	-	-	-	-	-	-
MAKDMGGG_00216	6.52e-94	-	-	-	S	-	-	-	Phage tail tube protein, TTP
MAKDMGGG_00217	8.17e-67	-	-	-	-	-	-	-	-
MAKDMGGG_00218	1.56e-102	-	-	-	-	-	-	-	-
MAKDMGGG_00219	7.26e-37	-	-	-	-	-	-	-	-
MAKDMGGG_00220	6.72e-08	-	-	-	-	-	-	-	-
MAKDMGGG_00221	2.82e-47	-	-	-	-	-	-	-	-
MAKDMGGG_00222	9.98e-214	-	-	-	S	-	-	-	Phage major capsid protein E
MAKDMGGG_00223	1.47e-72	-	-	-	-	-	-	-	-
MAKDMGGG_00224	1.85e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MAKDMGGG_00225	7.62e-192	-	-	-	S	-	-	-	Phage Mu protein F like protein
MAKDMGGG_00226	5.56e-38	-	-	-	S	-	-	-	Cysteine protease Prp
MAKDMGGG_00227	6.94e-273	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MAKDMGGG_00228	5.42e-277	-	-	-	S	-	-	-	Terminase-like family
MAKDMGGG_00229	6.38e-155	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
MAKDMGGG_00231	3.08e-79	-	-	-	K	-	-	-	Domain of unknown function (DUF4417)
MAKDMGGG_00232	1.19e-08	-	-	-	-	-	-	-	-
MAKDMGGG_00239	6.73e-41	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAKDMGGG_00240	4.88e-67	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MAKDMGGG_00242	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MAKDMGGG_00243	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MAKDMGGG_00244	5.61e-71	-	-	-	-	-	-	-	-
MAKDMGGG_00245	5.13e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MAKDMGGG_00246	8.04e-230	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MAKDMGGG_00247	6.77e-77	-	-	-	-	-	-	-	-
MAKDMGGG_00249	1.45e-10	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
MAKDMGGG_00250	9e-87	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MAKDMGGG_00252	7.32e-51	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAKDMGGG_00253	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MAKDMGGG_00254	3.5e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MAKDMGGG_00255	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MAKDMGGG_00256	1.03e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MAKDMGGG_00257	1.5e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MAKDMGGG_00258	8.12e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MAKDMGGG_00259	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MAKDMGGG_00260	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MAKDMGGG_00261	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MAKDMGGG_00262	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MAKDMGGG_00263	6.16e-237	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MAKDMGGG_00264	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAKDMGGG_00265	1.23e-162	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MAKDMGGG_00266	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MAKDMGGG_00267	9.45e-282	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MAKDMGGG_00268	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MAKDMGGG_00269	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MAKDMGGG_00270	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MAKDMGGG_00271	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MAKDMGGG_00272	2.96e-116	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MAKDMGGG_00273	7.76e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MAKDMGGG_00274	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
MAKDMGGG_00275	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MAKDMGGG_00276	1.16e-29	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
MAKDMGGG_00277	7.59e-56	-	-	-	L	-	-	-	Transposase
MAKDMGGG_00278	4.33e-102	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAKDMGGG_00281	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MAKDMGGG_00282	4.13e-190	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAKDMGGG_00285	3.66e-142	-	-	-	-	-	-	-	-
MAKDMGGG_00286	1.13e-62	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MAKDMGGG_00292	5.12e-76	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MAKDMGGG_00293	5.99e-113	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MAKDMGGG_00294	3.17e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MAKDMGGG_00295	9.68e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MAKDMGGG_00296	1.75e-20	-	-	-	EG	-	-	-	EamA-like transporter family
MAKDMGGG_00297	2.57e-159	-	-	-	EG	-	-	-	EamA-like transporter family
MAKDMGGG_00298	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MAKDMGGG_00300	2.35e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MAKDMGGG_00301	1.87e-132	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MAKDMGGG_00302	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MAKDMGGG_00303	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MAKDMGGG_00304	2.94e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MAKDMGGG_00305	9.36e-126	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKDMGGG_00306	2.26e-65	-	-	-	-	-	-	-	-
MAKDMGGG_00308	4.4e-54	-	-	-	-	-	-	-	-
MAKDMGGG_00309	9.42e-25	-	-	-	-	-	-	-	-
MAKDMGGG_00310	2.39e-55	-	-	-	E	-	-	-	Zn peptidase
MAKDMGGG_00311	2.29e-67	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAKDMGGG_00312	1.42e-35	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKDMGGG_00313	1.31e-81	-	-	-	S	-	-	-	DNA binding
MAKDMGGG_00319	3.71e-19	-	-	-	S	ko:K09946	-	ko00000	Domain of unknown function (DUF1508)
MAKDMGGG_00323	1.15e-99	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MAKDMGGG_00324	2.33e-78	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
MAKDMGGG_00325	1.52e-169	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MAKDMGGG_00326	1.05e-74	-	-	-	-	-	-	-	-
MAKDMGGG_00329	5.25e-70	-	-	-	S	-	-	-	ORF6C domain
MAKDMGGG_00337	1.87e-45	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAKDMGGG_00338	5.34e-68	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MAKDMGGG_00339	8.9e-89	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MAKDMGGG_00340	5.82e-286	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAKDMGGG_00341	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAKDMGGG_00342	4.95e-110	-	-	-	F	-	-	-	Hydrolase, NUDIX family
MAKDMGGG_00343	1.73e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MAKDMGGG_00344	3.81e-50	-	-	-	L	-	-	-	Transposase
MAKDMGGG_00346	4.67e-100	-	-	-	L	-	-	-	Transposase
MAKDMGGG_00347	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MAKDMGGG_00348	1.25e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MAKDMGGG_00349	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAKDMGGG_00350	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MAKDMGGG_00351	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MAKDMGGG_00352	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MAKDMGGG_00353	6.4e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MAKDMGGG_00354	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MAKDMGGG_00355	1.44e-232	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAKDMGGG_00356	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MAKDMGGG_00357	9.08e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MAKDMGGG_00358	3.69e-165	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MAKDMGGG_00359	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKDMGGG_00360	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MAKDMGGG_00361	4.8e-30	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKDMGGG_00362	3.84e-118	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKDMGGG_00363	1.73e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MAKDMGGG_00364	6.56e-165	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MAKDMGGG_00365	7.13e-134	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MAKDMGGG_00366	2.37e-250	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MAKDMGGG_00367	2.44e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MAKDMGGG_00368	1.61e-266	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MAKDMGGG_00369	2.2e-178	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MAKDMGGG_00370	2.21e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MAKDMGGG_00371	8.87e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKDMGGG_00372	6.9e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MAKDMGGG_00373	1.72e-87	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MAKDMGGG_00374	3.56e-133	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MAKDMGGG_00375	4.08e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MAKDMGGG_00376	1.38e-140	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MAKDMGGG_00377	2.4e-312	-	-	-	T	-	-	-	GHKL domain
MAKDMGGG_00378	1.5e-66	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MAKDMGGG_00379	6.01e-56	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MAKDMGGG_00380	5.88e-37	-	-	-	L	-	-	-	Transposase
MAKDMGGG_00386	1.87e-201	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MAKDMGGG_00387	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MAKDMGGG_00388	3.82e-157	-	-	-	S	-	-	-	repeat protein
MAKDMGGG_00389	4.02e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
MAKDMGGG_00390	3.84e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MAKDMGGG_00391	2.27e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MAKDMGGG_00392	1.1e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAKDMGGG_00393	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MAKDMGGG_00394	1.54e-33	-	-	-	-	-	-	-	-
MAKDMGGG_00395	1.01e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MAKDMGGG_00396	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MAKDMGGG_00397	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MAKDMGGG_00398	7.47e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MAKDMGGG_00399	1.13e-43	ylmH	-	-	S	-	-	-	S4 domain protein
MAKDMGGG_00400	3.28e-132	ylmH	-	-	S	-	-	-	S4 domain protein
MAKDMGGG_00401	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MAKDMGGG_00402	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MAKDMGGG_00403	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MAKDMGGG_00404	4.17e-291	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MAKDMGGG_00405	1.73e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MAKDMGGG_00406	5.52e-251	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MAKDMGGG_00407	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MAKDMGGG_00408	7.69e-127	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MAKDMGGG_00413	1.31e-26	-	-	-	G	-	-	-	COG0366 Glycosidases
MAKDMGGG_00416	3.71e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MAKDMGGG_00417	3.47e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MAKDMGGG_00418	9.38e-187	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MAKDMGGG_00419	2.89e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MAKDMGGG_00420	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKDMGGG_00421	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MAKDMGGG_00422	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
MAKDMGGG_00423	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MAKDMGGG_00424	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MAKDMGGG_00425	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MAKDMGGG_00426	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MAKDMGGG_00427	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MAKDMGGG_00428	1.19e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MAKDMGGG_00429	2.89e-59	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MAKDMGGG_00430	8.95e-251	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MAKDMGGG_00431	4.74e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MAKDMGGG_00432	7.5e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MAKDMGGG_00433	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MAKDMGGG_00434	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MAKDMGGG_00436	1.29e-231	-	-	-	G	-	-	-	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MAKDMGGG_00437	1.44e-195	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
MAKDMGGG_00438	9.98e-161	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
MAKDMGGG_00439	1.33e-170	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00440	8.52e-117	-	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKDMGGG_00441	2.91e-186	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MAKDMGGG_00442	3.11e-42	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAKDMGGG_00443	1.23e-29	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAKDMGGG_00445	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MAKDMGGG_00446	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MAKDMGGG_00447	6.82e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MAKDMGGG_00448	1.02e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
MAKDMGGG_00449	2.69e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MAKDMGGG_00450	1.46e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MAKDMGGG_00451	2.83e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MAKDMGGG_00452	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
MAKDMGGG_00453	1.82e-277	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MAKDMGGG_00454	7.78e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MAKDMGGG_00455	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MAKDMGGG_00456	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MAKDMGGG_00457	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MAKDMGGG_00458	6.05e-222	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MAKDMGGG_00459	3.61e-303	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
MAKDMGGG_00460	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MAKDMGGG_00461	3.99e-127	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MAKDMGGG_00462	8.09e-197	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MAKDMGGG_00463	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MAKDMGGG_00464	2.05e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MAKDMGGG_00465	9.02e-145	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MAKDMGGG_00466	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MAKDMGGG_00467	1.34e-151	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MAKDMGGG_00468	9.52e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
MAKDMGGG_00469	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
MAKDMGGG_00470	1.72e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MAKDMGGG_00471	3.65e-41	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MAKDMGGG_00474	1.76e-215	-	-	-	-	-	-	-	-
MAKDMGGG_00475	3.04e-122	-	-	-	K	-	-	-	acetyltransferase
MAKDMGGG_00476	4.68e-90	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MAKDMGGG_00478	1.68e-221	-	-	-	-	-	-	-	-
MAKDMGGG_00479	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MAKDMGGG_00480	3.47e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MAKDMGGG_00481	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
MAKDMGGG_00482	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MAKDMGGG_00483	4.31e-296	-	-	-	P	-	-	-	Chloride transporter, ClC family
MAKDMGGG_00484	1.13e-94	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MAKDMGGG_00485	2.39e-29	-	-	-	L	-	-	-	Transposase
MAKDMGGG_00489	1.38e-37	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MAKDMGGG_00490	2.22e-128	-	-	-	M	-	-	-	CotH kinase protein
MAKDMGGG_00492	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
MAKDMGGG_00493	1.7e-151	-	-	-	S	-	-	-	Phage tail protein
MAKDMGGG_00494	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAKDMGGG_00495	8.23e-28	-	-	-	-	-	-	-	-
MAKDMGGG_00497	3.57e-144	-	-	-	-	-	-	-	-
MAKDMGGG_00498	5.69e-100	-	-	-	-	-	-	-	-
MAKDMGGG_00499	1.85e-82	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MAKDMGGG_00500	6.4e-54	-	-	-	S	-	-	-	Phage head-tail joining protein
MAKDMGGG_00501	1.07e-85	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MAKDMGGG_00502	1.5e-196	-	-	-	S	-	-	-	Phage capsid family
MAKDMGGG_00503	5.63e-145	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
MAKDMGGG_00504	1.03e-303	-	-	-	S	-	-	-	Phage portal protein
MAKDMGGG_00507	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKDMGGG_00508	6.36e-50	-	-	-	S	-	-	-	Cytochrome B5
MAKDMGGG_00509	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
MAKDMGGG_00510	1.51e-52	-	-	-	S	-	-	-	Cytochrome B5
MAKDMGGG_00511	1.17e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MAKDMGGG_00513	6.64e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MAKDMGGG_00514	2.59e-226	-	-	-	E	ko:K03294	-	ko00000	amino acid
MAKDMGGG_00515	1.83e-31	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MAKDMGGG_00516	2.96e-37	-	-	-	LM	-	-	-	gp58-like protein
MAKDMGGG_00519	3.7e-44	-	-	-	-	-	-	-	-
MAKDMGGG_00520	9.06e-93	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MAKDMGGG_00521	6.92e-235	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MAKDMGGG_00522	5.39e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
MAKDMGGG_00523	1.49e-84	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
MAKDMGGG_00524	1.41e-93	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MAKDMGGG_00525	4.61e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKDMGGG_00526	7.16e-22	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MAKDMGGG_00527	1.58e-191	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MAKDMGGG_00528	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MAKDMGGG_00529	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MAKDMGGG_00530	4.9e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
MAKDMGGG_00531	7.18e-126	-	-	-	-	-	-	-	-
MAKDMGGG_00532	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MAKDMGGG_00533	2.53e-172	gspA	-	-	M	-	-	-	family 8
MAKDMGGG_00534	2.84e-204	-	-	-	S	-	-	-	Alpha beta hydrolase
MAKDMGGG_00535	4.52e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAKDMGGG_00536	1.12e-136	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MAKDMGGG_00537	2.76e-63	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MAKDMGGG_00538	3.42e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MAKDMGGG_00539	3.08e-211	yvgN	-	-	C	-	-	-	Aldo keto reductase
MAKDMGGG_00540	1.1e-54	-	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_00541	2.47e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKDMGGG_00542	9.44e-82	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MAKDMGGG_00543	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKDMGGG_00544	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MAKDMGGG_00545	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MAKDMGGG_00546	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MAKDMGGG_00547	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MAKDMGGG_00548	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MAKDMGGG_00549	1.66e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MAKDMGGG_00550	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAKDMGGG_00551	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MAKDMGGG_00552	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MAKDMGGG_00553	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MAKDMGGG_00554	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MAKDMGGG_00555	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MAKDMGGG_00556	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAKDMGGG_00557	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MAKDMGGG_00558	5.22e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MAKDMGGG_00559	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MAKDMGGG_00560	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MAKDMGGG_00561	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MAKDMGGG_00562	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MAKDMGGG_00563	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MAKDMGGG_00564	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MAKDMGGG_00565	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MAKDMGGG_00566	1.64e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MAKDMGGG_00567	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MAKDMGGG_00568	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MAKDMGGG_00569	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MAKDMGGG_00570	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MAKDMGGG_00571	1.07e-40	-	-	-	L	-	-	-	Transposase
MAKDMGGG_00572	1.55e-55	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MAKDMGGG_00573	3.38e-93	isp	-	-	L	-	-	-	Transposase
MAKDMGGG_00574	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MAKDMGGG_00575	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MAKDMGGG_00576	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MAKDMGGG_00577	2.44e-119	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
MAKDMGGG_00578	2.13e-259	-	-	-	-	-	-	-	-
MAKDMGGG_00579	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKDMGGG_00580	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MAKDMGGG_00581	7e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKDMGGG_00582	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MAKDMGGG_00583	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MAKDMGGG_00584	7.04e-247	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAKDMGGG_00585	2.3e-229	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
MAKDMGGG_00591	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MAKDMGGG_00592	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MAKDMGGG_00594	2.79e-153	-	-	-	I	-	-	-	phosphatase
MAKDMGGG_00595	3.68e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MAKDMGGG_00596	3.78e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAKDMGGG_00597	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MAKDMGGG_00598	1.15e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
MAKDMGGG_00599	4.92e-213	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MAKDMGGG_00600	7.33e-152	-	-	-	S	-	-	-	membrane
MAKDMGGG_00601	2.34e-142	-	-	-	S	-	-	-	VIT family
MAKDMGGG_00602	3.97e-107	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MAKDMGGG_00603	1.97e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00604	5.46e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKDMGGG_00605	3.54e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKDMGGG_00606	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKDMGGG_00607	1.44e-275	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKDMGGG_00608	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAKDMGGG_00609	1.11e-72	-	-	-	-	-	-	-	-
MAKDMGGG_00610	3.21e-99	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MAKDMGGG_00611	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKDMGGG_00612	1.03e-157	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MAKDMGGG_00613	3.12e-250	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MAKDMGGG_00614	3.64e-116	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MAKDMGGG_00615	3.7e-19	-	-	-	-	-	-	-	-
MAKDMGGG_00616	2.72e-250	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MAKDMGGG_00617	6.95e-122	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
MAKDMGGG_00618	1.08e-57	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAKDMGGG_00619	1.07e-111	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAKDMGGG_00620	2.32e-104	-	-	-	-	-	-	-	-
MAKDMGGG_00621	4.74e-164	-	-	-	M	-	-	-	Lysin motif
MAKDMGGG_00622	1.55e-254	-	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_00623	3.62e-131	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MAKDMGGG_00624	1.4e-251	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MAKDMGGG_00625	7.66e-103	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MAKDMGGG_00626	3.4e-196	-	-	-	J	-	-	-	Methyltransferase
MAKDMGGG_00627	1.12e-242	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MAKDMGGG_00628	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MAKDMGGG_00629	1.82e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MAKDMGGG_00630	3.83e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00631	2.47e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
MAKDMGGG_00633	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MAKDMGGG_00634	2.32e-280	yhaN	-	-	L	-	-	-	AAA domain
MAKDMGGG_00635	9.95e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MAKDMGGG_00636	3.28e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
MAKDMGGG_00637	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MAKDMGGG_00638	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
MAKDMGGG_00639	5.79e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MAKDMGGG_00640	4.1e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
MAKDMGGG_00641	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MAKDMGGG_00642	1.85e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MAKDMGGG_00643	5.25e-59	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MAKDMGGG_00644	1.87e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MAKDMGGG_00645	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MAKDMGGG_00646	3.01e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MAKDMGGG_00647	4.63e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MAKDMGGG_00648	2.04e-115	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MAKDMGGG_00649	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MAKDMGGG_00650	5.37e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MAKDMGGG_00651	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MAKDMGGG_00652	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MAKDMGGG_00653	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MAKDMGGG_00655	4.34e-92	-	-	-	L	-	-	-	HNH nucleases
MAKDMGGG_00656	1.05e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
MAKDMGGG_00657	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKDMGGG_00659	4.54e-253	-	-	-	S	-	-	-	Phage portal protein
MAKDMGGG_00660	4.12e-136	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MAKDMGGG_00661	2.66e-255	-	-	-	S	-	-	-	Phage capsid family
MAKDMGGG_00662	1.57e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MAKDMGGG_00666	5.43e-97	-	-	-	S	-	-	-	Phage tail tube protein
MAKDMGGG_00667	2.92e-13	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
MAKDMGGG_00669	4.48e-298	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MAKDMGGG_00670	1.6e-103	-	-	-	S	-	-	-	Phage tail protein
MAKDMGGG_00671	2.56e-173	-	-	-	M	-	-	-	Prophage endopeptidase tail
MAKDMGGG_00673	8.04e-129	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MAKDMGGG_00674	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MAKDMGGG_00675	9.73e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAKDMGGG_00677	1.01e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
MAKDMGGG_00678	9.58e-112	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
MAKDMGGG_00679	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAKDMGGG_00681	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MAKDMGGG_00682	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MAKDMGGG_00683	3.52e-161	-	-	-	-	-	-	-	-
MAKDMGGG_00684	3.76e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MAKDMGGG_00685	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MAKDMGGG_00686	4.98e-272	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MAKDMGGG_00687	4.52e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_00688	5.08e-207	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
MAKDMGGG_00689	5.77e-140	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKDMGGG_00690	1.68e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00691	1.13e-137	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
MAKDMGGG_00692	3.14e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MAKDMGGG_00693	5.58e-249	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
MAKDMGGG_00694	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MAKDMGGG_00696	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MAKDMGGG_00697	1.14e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MAKDMGGG_00698	4.71e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MAKDMGGG_00699	5.29e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MAKDMGGG_00700	7.46e-45	-	-	-	S	-	-	-	Transglycosylase associated protein
MAKDMGGG_00701	3.27e-13	-	-	-	S	-	-	-	CsbD-like
MAKDMGGG_00702	7.72e-231	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKDMGGG_00703	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
MAKDMGGG_00704	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
MAKDMGGG_00705	7.13e-52	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MAKDMGGG_00706	3.82e-192	-	-	-	-	-	-	-	-
MAKDMGGG_00707	4.56e-34	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
MAKDMGGG_00708	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MAKDMGGG_00709	9.66e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
MAKDMGGG_00710	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
MAKDMGGG_00711	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MAKDMGGG_00712	1.3e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MAKDMGGG_00713	1.69e-294	-	-	-	-	-	-	-	-
MAKDMGGG_00714	2.08e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKDMGGG_00715	1.04e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKDMGGG_00716	1.44e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKDMGGG_00717	5.08e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MAKDMGGG_00718	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MAKDMGGG_00719	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MAKDMGGG_00720	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MAKDMGGG_00721	3.42e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MAKDMGGG_00722	1.56e-285	yagE	-	-	E	-	-	-	amino acid
MAKDMGGG_00723	0.0	-	-	-	M	-	-	-	NlpC/P60 family
MAKDMGGG_00724	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MAKDMGGG_00725	2.18e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKDMGGG_00726	2.63e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
MAKDMGGG_00727	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
MAKDMGGG_00728	1.28e-195	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MAKDMGGG_00729	1.99e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MAKDMGGG_00730	9.26e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MAKDMGGG_00731	1.3e-204	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MAKDMGGG_00732	1.11e-15	-	-	-	S	-	-	-	Domain of unknown function DUF1829
MAKDMGGG_00734	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAKDMGGG_00735	1.81e-180	-	-	-	M	-	-	-	Glycosyl transferase family 2
MAKDMGGG_00736	2.18e-121	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MAKDMGGG_00737	2.78e-98	-	-	-	S	-	-	-	Bacteriophage holin family
MAKDMGGG_00740	4.99e-118	-	-	-	S	-	-	-	peptidoglycan catabolic process
MAKDMGGG_00741	1.36e-194	-	-	-	S	-	-	-	peptidoglycan catabolic process
MAKDMGGG_00743	1.61e-229	-	-	-	S	-	-	-	peptidoglycan catabolic process
MAKDMGGG_00745	2.04e-59	-	-	-	S	-	-	-	Pfam:Phage_TAC_12
MAKDMGGG_00746	3.82e-110	-	-	-	S	-	-	-	Phage major tail protein 2
MAKDMGGG_00747	6.25e-57	-	-	-	-	-	-	-	-
MAKDMGGG_00748	1.27e-57	-	-	-	S	-	-	-	exonuclease activity
MAKDMGGG_00750	3.3e-61	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MAKDMGGG_00751	3.17e-146	-	-	-	-	-	-	-	-
MAKDMGGG_00752	1.55e-83	-	-	-	S	-	-	-	aminoacyl-tRNA ligase activity
MAKDMGGG_00754	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
MAKDMGGG_00755	1.28e-225	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MAKDMGGG_00756	2.11e-274	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MAKDMGGG_00757	2.19e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MAKDMGGG_00759	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAKDMGGG_00760	3.42e-235	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKDMGGG_00761	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MAKDMGGG_00762	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MAKDMGGG_00763	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MAKDMGGG_00764	1.21e-70	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MAKDMGGG_00765	4.19e-106	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MAKDMGGG_00766	1.63e-152	-	-	-	L	-	-	-	Integrase
MAKDMGGG_00767	1.33e-196	-	-	-	EG	-	-	-	EamA-like transporter family
MAKDMGGG_00768	1.1e-166	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
MAKDMGGG_00769	5.76e-128	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
MAKDMGGG_00770	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MAKDMGGG_00771	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MAKDMGGG_00772	3.94e-37	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
MAKDMGGG_00773	4.07e-52	-	-	-	H	-	-	-	geranyltranstransferase activity
MAKDMGGG_00774	9.73e-275	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
MAKDMGGG_00775	9.9e-49	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
MAKDMGGG_00776	2.29e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
MAKDMGGG_00777	2.96e-100	-	-	-	S	-	-	-	Flavodoxin
MAKDMGGG_00778	2.63e-168	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MAKDMGGG_00779	1.96e-179	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MAKDMGGG_00780	1.45e-233	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MAKDMGGG_00781	2.28e-203	-	-	-	-	-	-	-	-
MAKDMGGG_00782	2.19e-100	-	-	-	-	-	-	-	-
MAKDMGGG_00783	1.29e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MAKDMGGG_00784	2.01e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MAKDMGGG_00785	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00786	4.05e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MAKDMGGG_00787	1.22e-112	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MAKDMGGG_00788	5.61e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MAKDMGGG_00789	9.07e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
MAKDMGGG_00790	1.6e-219	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MAKDMGGG_00791	1.65e-140	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
MAKDMGGG_00792	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MAKDMGGG_00793	1.71e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MAKDMGGG_00794	1.44e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAKDMGGG_00795	2.73e-207	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MAKDMGGG_00796	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MAKDMGGG_00797	3.08e-209	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MAKDMGGG_00798	1.56e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MAKDMGGG_00799	1.43e-131	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MAKDMGGG_00800	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MAKDMGGG_00801	1.36e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
MAKDMGGG_00802	2.53e-209	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
MAKDMGGG_00803	3.23e-269	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MAKDMGGG_00804	3.37e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MAKDMGGG_00805	1.2e-200	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
MAKDMGGG_00806	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
MAKDMGGG_00807	2.5e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
MAKDMGGG_00808	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MAKDMGGG_00809	3.83e-233	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MAKDMGGG_00810	3.18e-198	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MAKDMGGG_00811	2.29e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MAKDMGGG_00812	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MAKDMGGG_00813	2.47e-65	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MAKDMGGG_00814	1.11e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MAKDMGGG_00815	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAKDMGGG_00816	1.18e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MAKDMGGG_00817	2.41e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MAKDMGGG_00818	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MAKDMGGG_00819	1.63e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MAKDMGGG_00820	3.26e-95	-	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_00821	1.33e-110	-	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_00823	9.89e-86	-	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_00824	1.69e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MAKDMGGG_00825	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MAKDMGGG_00826	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
MAKDMGGG_00827	2.59e-145	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MAKDMGGG_00828	2.29e-232	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
MAKDMGGG_00829	9.98e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MAKDMGGG_00830	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
MAKDMGGG_00831	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
MAKDMGGG_00832	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MAKDMGGG_00833	1.82e-112	-	-	-	-	-	-	-	-
MAKDMGGG_00835	1.28e-75	-	-	-	-	-	-	-	-
MAKDMGGG_00836	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MAKDMGGG_00843	6.37e-130	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
MAKDMGGG_00844	1.82e-57	-	-	-	-	-	-	-	-
MAKDMGGG_00848	1.3e-24	-	-	-	S	-	-	-	Helix-turn-helix domain
MAKDMGGG_00850	7.72e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MAKDMGGG_00851	1.26e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MAKDMGGG_00852	1.53e-107	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKDMGGG_00853	4.89e-16	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MAKDMGGG_00854	1.42e-102	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MAKDMGGG_00855	3.23e-211	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MAKDMGGG_00856	8.91e-141	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAKDMGGG_00857	9.13e-158	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MAKDMGGG_00858	4.94e-217	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MAKDMGGG_00859	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MAKDMGGG_00860	0.0	arcT	-	-	E	-	-	-	Dipeptidase
MAKDMGGG_00861	2.2e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
MAKDMGGG_00862	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
MAKDMGGG_00863	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
MAKDMGGG_00864	6.57e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAKDMGGG_00865	7.98e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MAKDMGGG_00866	3.48e-288	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MAKDMGGG_00867	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAKDMGGG_00868	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MAKDMGGG_00869	5.62e-37	-	-	-	-	-	-	-	-
MAKDMGGG_00870	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MAKDMGGG_00871	1.44e-126	-	-	-	S	-	-	-	Pfam:DUF3816
MAKDMGGG_00872	3.86e-182	-	-	-	G	-	-	-	MucBP domain
MAKDMGGG_00873	5.54e-146	-	-	-	-	-	-	-	-
MAKDMGGG_00874	1.3e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00875	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
MAKDMGGG_00876	0.0	-	-	-	S	-	-	-	Peptidase, M23
MAKDMGGG_00877	2.76e-90	-	-	-	S	-	-	-	Peptidase, M23
MAKDMGGG_00878	1.14e-130	-	-	-	M	-	-	-	NlpC/P60 family
MAKDMGGG_00879	6.81e-273	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MAKDMGGG_00880	9.52e-124	-	-	-	S	-	-	-	AmiS/UreI family transporter
MAKDMGGG_00881	4.88e-60	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
MAKDMGGG_00882	2.83e-84	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
MAKDMGGG_00883	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
MAKDMGGG_00884	2.21e-82	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MAKDMGGG_00885	1.97e-168	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MAKDMGGG_00886	2.42e-146	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MAKDMGGG_00887	2.25e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MAKDMGGG_00888	1.79e-55	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKDMGGG_00889	4.2e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MAKDMGGG_00890	2.5e-233	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
MAKDMGGG_00891	1.93e-182	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MAKDMGGG_00892	6.63e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKDMGGG_00893	7.17e-171	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
MAKDMGGG_00894	1.11e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MAKDMGGG_00895	1.26e-191	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MAKDMGGG_00896	7.4e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MAKDMGGG_00897	2.48e-174	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MAKDMGGG_00898	2.89e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MAKDMGGG_00899	3.66e-183	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAKDMGGG_00901	1.22e-53	-	-	-	-	-	-	-	-
MAKDMGGG_00902	5.38e-60	-	-	-	-	-	-	-	-
MAKDMGGG_00903	7.75e-260	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MAKDMGGG_00904	5.53e-132	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MAKDMGGG_00905	5.04e-279	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MAKDMGGG_00906	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MAKDMGGG_00907	2.63e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MAKDMGGG_00908	1.43e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MAKDMGGG_00909	2.57e-90	-	-	-	-	-	-	-	-
MAKDMGGG_00911	9.17e-59	-	-	-	-	-	-	-	-
MAKDMGGG_00912	1.43e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MAKDMGGG_00913	1.52e-43	-	-	-	-	-	-	-	-
MAKDMGGG_00914	2.04e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAKDMGGG_00915	4e-235	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
MAKDMGGG_00916	1.53e-146	-	-	-	-	-	-	-	-
MAKDMGGG_00917	2.71e-144	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MAKDMGGG_00918	1.75e-221	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAKDMGGG_00919	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MAKDMGGG_00920	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MAKDMGGG_00921	4.68e-14	-	-	-	-	-	-	-	-
MAKDMGGG_00922	3.78e-23	-	-	-	-	-	-	-	-
MAKDMGGG_00923	5.67e-70	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MAKDMGGG_00924	8.38e-37	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00925	1.67e-58	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_00926	4.46e-67	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKDMGGG_00927	4.07e-138	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MAKDMGGG_00928	1.44e-252	-	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_00929	9.59e-148	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
MAKDMGGG_00930	4.22e-244	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MAKDMGGG_00931	1.18e-124	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MAKDMGGG_00932	2.16e-285	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MAKDMGGG_00933	6.42e-101	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MAKDMGGG_00934	1.49e-145	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
MAKDMGGG_00935	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MAKDMGGG_00936	1.42e-270	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MAKDMGGG_00937	2.71e-101	-	-	-	K	ko:K03091	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
MAKDMGGG_00938	4.73e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
MAKDMGGG_00939	3.31e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MAKDMGGG_00940	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MAKDMGGG_00941	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MAKDMGGG_00942	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
MAKDMGGG_00943	1.87e-229	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAKDMGGG_00944	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MAKDMGGG_00945	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAKDMGGG_00946	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
MAKDMGGG_00947	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MAKDMGGG_00948	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MAKDMGGG_00949	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MAKDMGGG_00950	2.36e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MAKDMGGG_00951	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MAKDMGGG_00952	1.05e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MAKDMGGG_00953	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MAKDMGGG_00954	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MAKDMGGG_00955	1.75e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MAKDMGGG_00956	8.27e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKDMGGG_00957	8.29e-84	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MAKDMGGG_00958	1.43e-89	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MAKDMGGG_00959	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MAKDMGGG_00960	2.65e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MAKDMGGG_00961	1.85e-208	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MAKDMGGG_00962	4.29e-85	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MAKDMGGG_00963	4.24e-34	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MAKDMGGG_00964	1.29e-121	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MAKDMGGG_00965	3.18e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MAKDMGGG_00966	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MAKDMGGG_00967	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MAKDMGGG_00968	2.84e-241	-	-	-	S	-	-	-	Helix-turn-helix domain
MAKDMGGG_00969	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MAKDMGGG_00970	1.31e-65	-	-	-	M	-	-	-	Lysin motif
MAKDMGGG_00971	7.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MAKDMGGG_00972	1.52e-267	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MAKDMGGG_00973	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MAKDMGGG_00974	1.08e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MAKDMGGG_00975	4.83e-118	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MAKDMGGG_00976	2.21e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MAKDMGGG_00977	9.47e-86	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MAKDMGGG_00978	1.13e-40	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MAKDMGGG_00980	4.13e-147	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MAKDMGGG_00981	5.62e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MAKDMGGG_00982	7.72e-49	ytpP	-	-	CO	-	-	-	Thioredoxin
MAKDMGGG_00983	3.92e-52	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKDMGGG_00985	1.01e-122	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
MAKDMGGG_00986	8.86e-177	trxB	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Glucose inhibited division protein A
MAKDMGGG_00987	2.9e-33	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
MAKDMGGG_00988	3.3e-91	M1-798	-	-	K	-	-	-	Rhodanese Homology Domain
MAKDMGGG_00989	9.04e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MAKDMGGG_00990	1.75e-179	-	-	-	L	-	-	-	Bacterial dnaA protein
MAKDMGGG_00991	1.09e-290	-	-	-	L	-	-	-	Integrase core domain
MAKDMGGG_00992	5.75e-49	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
MAKDMGGG_00993	0.0	-	-	-	L	-	-	-	PLD-like domain
MAKDMGGG_00995	1.86e-79	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAKDMGGG_00996	1.86e-142	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
MAKDMGGG_00997	1.32e-92	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MAKDMGGG_00998	1.77e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MAKDMGGG_00999	6.56e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAKDMGGG_01000	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAKDMGGG_01001	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MAKDMGGG_01002	3.54e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAKDMGGG_01003	1.97e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MAKDMGGG_01004	2.25e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MAKDMGGG_01005	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MAKDMGGG_01006	7.4e-71	-	-	-	-	-	-	-	-
MAKDMGGG_01007	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MAKDMGGG_01008	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MAKDMGGG_01009	2.17e-160	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAKDMGGG_01010	1.26e-47	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MAKDMGGG_01011	5e-32	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAKDMGGG_01012	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MAKDMGGG_01013	4.5e-152	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MAKDMGGG_01014	1.04e-69	-	-	-	-	-	-	-	-
MAKDMGGG_01015	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MAKDMGGG_01016	2.48e-103	-	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_01017	7.14e-187	-	-	-	S	-	-	-	Cof-like hydrolase
MAKDMGGG_01018	1.31e-108	lytE	-	-	M	-	-	-	Lysin motif
MAKDMGGG_01020	9.04e-171	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
MAKDMGGG_01021	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MAKDMGGG_01022	1.34e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MAKDMGGG_01023	1.36e-150	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MAKDMGGG_01024	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MAKDMGGG_01025	9.79e-37	-	-	-	-	-	-	-	-
MAKDMGGG_01026	6.1e-276	xylR	-	-	GK	-	-	-	ROK family
MAKDMGGG_01028	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MAKDMGGG_01029	1.04e-254	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MAKDMGGG_01030	9.35e-92	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MAKDMGGG_01031	1.01e-177	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MAKDMGGG_01032	4.21e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
MAKDMGGG_01033	2.51e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MAKDMGGG_01034	7.39e-293	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MAKDMGGG_01035	1.62e-256	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
MAKDMGGG_01036	2.04e-65	-	-	-	-	-	-	-	-
MAKDMGGG_01037	1.08e-157	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MAKDMGGG_01039	3.32e-72	-	-	-	-	-	-	-	-
MAKDMGGG_01040	1.08e-147	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
MAKDMGGG_01042	1.58e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MAKDMGGG_01043	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MAKDMGGG_01045	4.7e-231	-	-	-	S	-	-	-	associated with various cellular activities
MAKDMGGG_01046	8e-293	-	-	-	S	-	-	-	Putative metallopeptidase domain
MAKDMGGG_01047	1.21e-63	-	-	-	-	-	-	-	-
MAKDMGGG_01048	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MAKDMGGG_01049	2.49e-141	-	-	-	K	-	-	-	Helix-turn-helix domain
MAKDMGGG_01050	3.48e-112	ymdB	-	-	S	-	-	-	Macro domain protein
MAKDMGGG_01051	1.3e-247	-	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_01052	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAKDMGGG_01053	1.38e-67	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MAKDMGGG_01054	5.95e-210	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MAKDMGGG_01055	4.33e-196	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MAKDMGGG_01056	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MAKDMGGG_01057	2.48e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01058	1.19e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
MAKDMGGG_01059	2.7e-172	XK27_10500	-	-	K	-	-	-	response regulator
MAKDMGGG_01060	4.18e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
MAKDMGGG_01061	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MAKDMGGG_01062	3.2e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MAKDMGGG_01063	1.69e-256	-	-	-	-	-	-	-	-
MAKDMGGG_01064	7.19e-68	-	-	-	-	-	-	-	-
MAKDMGGG_01065	1.21e-48	-	-	-	-	-	-	-	-
MAKDMGGG_01066	3.75e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MAKDMGGG_01067	7.76e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MAKDMGGG_01068	3.01e-224	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MAKDMGGG_01069	1.79e-288	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MAKDMGGG_01070	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MAKDMGGG_01071	6.6e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MAKDMGGG_01072	2.46e-128	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
MAKDMGGG_01075	7.21e-24	-	-	-	UW	-	-	-	Tetratricopeptide repeat
MAKDMGGG_01077	1.75e-243	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MAKDMGGG_01078	4.06e-286	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MAKDMGGG_01079	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MAKDMGGG_01080	4.47e-199	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
MAKDMGGG_01081	1.01e-268	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
MAKDMGGG_01082	9.35e-244	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MAKDMGGG_01083	1.77e-205	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
MAKDMGGG_01084	1.53e-112	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MAKDMGGG_01085	5.3e-200	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAKDMGGG_01086	1.61e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MAKDMGGG_01087	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MAKDMGGG_01088	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MAKDMGGG_01089	7.12e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MAKDMGGG_01090	8.58e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MAKDMGGG_01091	5.64e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MAKDMGGG_01092	2.8e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MAKDMGGG_01093	8.54e-305	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MAKDMGGG_01094	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MAKDMGGG_01095	2.18e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
MAKDMGGG_01096	9.9e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MAKDMGGG_01097	9.76e-161	vanR	-	-	K	-	-	-	response regulator
MAKDMGGG_01098	6.19e-263	hpk31	-	-	T	-	-	-	Histidine kinase
MAKDMGGG_01100	2.98e-222	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MAKDMGGG_01102	4.65e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MAKDMGGG_01103	8.81e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAKDMGGG_01104	9.64e-188	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MAKDMGGG_01105	4.16e-198	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKDMGGG_01106	7.68e-62	-	-	-	-	-	-	-	-
MAKDMGGG_01108	1.35e-117	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MAKDMGGG_01109	2.19e-305	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
MAKDMGGG_01110	5.38e-113	-	-	-	-	-	-	-	-
MAKDMGGG_01111	2.32e-153	pnb	-	-	C	-	-	-	nitroreductase
MAKDMGGG_01112	2.78e-38	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MAKDMGGG_01113	2.42e-191	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MAKDMGGG_01114	2.54e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MAKDMGGG_01115	7.66e-96	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAKDMGGG_01116	1.04e-33	-	-	-	-	-	-	-	-
MAKDMGGG_01117	3.97e-125	-	-	-	-	-	-	-	-
MAKDMGGG_01118	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MAKDMGGG_01119	9.71e-233	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKDMGGG_01120	1.17e-254	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
MAKDMGGG_01122	2.05e-110	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
MAKDMGGG_01125	1.01e-39	-	-	-	L	-	-	-	HNH endonuclease
MAKDMGGG_01126	3.36e-25	terS	-	-	L	-	-	-	Phage terminase, small subunit
MAKDMGGG_01127	1.52e-252	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKDMGGG_01128	1.64e-179	-	-	-	S	-	-	-	Phage portal protein
MAKDMGGG_01129	1.88e-231	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
MAKDMGGG_01130	2.41e-26	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MAKDMGGG_01131	4.61e-21	-	-	-	-	-	-	-	-
MAKDMGGG_01133	1.1e-158	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MAKDMGGG_01134	1.66e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MAKDMGGG_01135	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MAKDMGGG_01136	2.22e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
MAKDMGGG_01137	9.29e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MAKDMGGG_01139	1.75e-65	-	-	-	-	-	-	-	-
MAKDMGGG_01140	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MAKDMGGG_01143	1.19e-249	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MAKDMGGG_01144	2.73e-164	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MAKDMGGG_01148	2.4e-303	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MAKDMGGG_01150	4.64e-96	-	-	-	O	-	-	-	OsmC-like protein
MAKDMGGG_01151	6.84e-168	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKDMGGG_01152	1.99e-19	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKDMGGG_01153	9.3e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MAKDMGGG_01154	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
MAKDMGGG_01155	6.4e-262	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
MAKDMGGG_01156	1.92e-126	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MAKDMGGG_01157	2.13e-204	mleR	-	-	K	-	-	-	LysR family
MAKDMGGG_01158	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
MAKDMGGG_01159	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MAKDMGGG_01160	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MAKDMGGG_01161	6.01e-166	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAKDMGGG_01162	6.12e-216	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MAKDMGGG_01163	8.74e-158	citR	-	-	K	-	-	-	sugar-binding domain protein
MAKDMGGG_01164	4.87e-261	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MAKDMGGG_01165	2.32e-43	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MAKDMGGG_01166	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MAKDMGGG_01167	2.78e-265	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MAKDMGGG_01168	4.41e-57	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MAKDMGGG_01169	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MAKDMGGG_01170	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
MAKDMGGG_01171	2.63e-113	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
MAKDMGGG_01172	1.38e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKDMGGG_01173	8.51e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01174	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01175	4.81e-50	-	-	-	-	-	-	-	-
MAKDMGGG_01176	8.78e-36	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MAKDMGGG_01177	2.53e-207	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKDMGGG_01179	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MAKDMGGG_01180	7.94e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MAKDMGGG_01181	6e-29	-	-	-	I	-	-	-	Alpha beta
MAKDMGGG_01182	2.33e-195	-	-	-	I	-	-	-	Alpha beta
MAKDMGGG_01183	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_01184	5.46e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MAKDMGGG_01185	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MAKDMGGG_01186	4.66e-201	-	-	-	K	-	-	-	LysR family
MAKDMGGG_01187	1.8e-136	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MAKDMGGG_01188	4.45e-193	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MAKDMGGG_01190	3.43e-25	-	-	-	-	-	-	-	-
MAKDMGGG_01195	4.45e-70	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
MAKDMGGG_01196	1.03e-68	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MAKDMGGG_01197	1.29e-05	-	-	-	L	-	-	-	HNH nucleases
MAKDMGGG_01198	6.85e-175	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
MAKDMGGG_01199	5.45e-177	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MAKDMGGG_01203	3.55e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAKDMGGG_01207	1.61e-145	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
MAKDMGGG_01208	5.47e-34	-	-	-	-	-	-	-	-
MAKDMGGG_01209	7.31e-40	-	-	-	K	-	-	-	Transcriptional regulator, Cro CI family
MAKDMGGG_01211	6.37e-22	-	-	-	-	-	-	-	-
MAKDMGGG_01212	3.84e-126	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
MAKDMGGG_01213	8.68e-44	-	-	-	-	-	-	-	-
MAKDMGGG_01214	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
MAKDMGGG_01215	1.78e-209	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MAKDMGGG_01217	4.76e-137	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
MAKDMGGG_01218	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MAKDMGGG_01219	2.27e-97	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MAKDMGGG_01220	2.12e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKDMGGG_01221	6.32e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MAKDMGGG_01222	1.21e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
MAKDMGGG_01223	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MAKDMGGG_01224	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MAKDMGGG_01225	1.49e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MAKDMGGG_01226	1.81e-309	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MAKDMGGG_01227	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MAKDMGGG_01228	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MAKDMGGG_01229	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MAKDMGGG_01230	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MAKDMGGG_01231	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MAKDMGGG_01232	1.14e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAKDMGGG_01233	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MAKDMGGG_01234	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MAKDMGGG_01235	3.8e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MAKDMGGG_01236	1.62e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MAKDMGGG_01237	1.35e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKDMGGG_01238	6.22e-65	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKDMGGG_01239	6.16e-149	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MAKDMGGG_01240	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MAKDMGGG_01241	8.5e-120	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MAKDMGGG_01242	1.96e-17	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MAKDMGGG_01243	1.49e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MAKDMGGG_01244	8.94e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MAKDMGGG_01245	3.9e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MAKDMGGG_01246	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MAKDMGGG_01247	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MAKDMGGG_01248	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
MAKDMGGG_01249	3.22e-48	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MAKDMGGG_01250	9.76e-298	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
MAKDMGGG_01251	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MAKDMGGG_01252	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MAKDMGGG_01253	1.03e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MAKDMGGG_01254	1.71e-241	ampC	-	-	V	-	-	-	Beta-lactamase
MAKDMGGG_01255	1.8e-72	-	-	-	-	-	-	-	-
MAKDMGGG_01256	4.13e-28	-	-	-	M	-	-	-	domain protein
MAKDMGGG_01257	0.0	-	-	-	M	-	-	-	domain protein
MAKDMGGG_01258	7.54e-130	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MAKDMGGG_01259	1.96e-194	-	-	-	S	-	-	-	Helix-turn-helix domain
MAKDMGGG_01260	1.83e-315	ymfH	-	-	S	-	-	-	Peptidase M16
MAKDMGGG_01261	4.8e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MAKDMGGG_01262	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MAKDMGGG_01263	1.02e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01264	6.32e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKDMGGG_01265	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
MAKDMGGG_01266	1.1e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MAKDMGGG_01267	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MAKDMGGG_01268	2.96e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MAKDMGGG_01269	3.38e-309	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MAKDMGGG_01270	2.18e-255	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MAKDMGGG_01271	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MAKDMGGG_01272	3.06e-203	-	-	-	EG	-	-	-	EamA-like transporter family
MAKDMGGG_01273	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAKDMGGG_01274	9.72e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MAKDMGGG_01275	4.06e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MAKDMGGG_01277	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MAKDMGGG_01278	1.16e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MAKDMGGG_01279	9.44e-223	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
MAKDMGGG_01280	1.14e-188	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MAKDMGGG_01281	4.97e-54	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
MAKDMGGG_01282	1.56e-202	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MAKDMGGG_01284	1.32e-277	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
MAKDMGGG_01285	1.37e-152	-	-	-	-	-	-	-	-
MAKDMGGG_01287	2.67e-266	-	-	-	M	-	-	-	Glycosyl transferase
MAKDMGGG_01288	7.46e-212	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MAKDMGGG_01289	2.31e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MAKDMGGG_01290	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MAKDMGGG_01291	1.59e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MAKDMGGG_01292	1.14e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
MAKDMGGG_01293	3.77e-114	-	-	-	Q	-	-	-	Methyltransferase
MAKDMGGG_01294	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MAKDMGGG_01295	3.71e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
MAKDMGGG_01296	3.11e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MAKDMGGG_01297	6.86e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAKDMGGG_01298	2.08e-159	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
MAKDMGGG_01299	3.4e-37	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
MAKDMGGG_01300	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
MAKDMGGG_01301	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
MAKDMGGG_01302	7.66e-192	-	-	-	O	-	-	-	Band 7 protein
MAKDMGGG_01303	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MAKDMGGG_01304	1.97e-28	-	-	-	-	-	-	-	-
MAKDMGGG_01305	2.47e-112	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MAKDMGGG_01306	2.29e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MAKDMGGG_01307	3.61e-61	-	-	-	-	-	-	-	-
MAKDMGGG_01308	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
MAKDMGGG_01309	8.01e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
MAKDMGGG_01310	8.1e-199	yvgN	-	-	S	-	-	-	Aldo keto reductase
MAKDMGGG_01311	3.33e-121	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
MAKDMGGG_01312	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MAKDMGGG_01313	3.16e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MAKDMGGG_01314	1.84e-203	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
MAKDMGGG_01315	6.21e-172	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
MAKDMGGG_01316	2.3e-209	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MAKDMGGG_01317	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MAKDMGGG_01318	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MAKDMGGG_01319	3.5e-223	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MAKDMGGG_01320	8.64e-199	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MAKDMGGG_01321	4.51e-184	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
MAKDMGGG_01322	1.15e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MAKDMGGG_01323	8.7e-166	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MAKDMGGG_01324	1.81e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MAKDMGGG_01325	9.65e-95	-	-	-	S	ko:K02348	-	ko00000	Gnat family
MAKDMGGG_01326	2e-14	-	-	-	GM	-	-	-	NmrA-like family
MAKDMGGG_01327	4.55e-68	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAKDMGGG_01328	1.3e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MAKDMGGG_01329	3.67e-74	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAKDMGGG_01330	3.32e-300	-	-	-	-	-	-	-	-
MAKDMGGG_01331	3.09e-268	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MAKDMGGG_01332	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MAKDMGGG_01333	1.97e-143	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
MAKDMGGG_01334	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MAKDMGGG_01335	1.79e-119	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MAKDMGGG_01336	3.68e-279	potE	-	-	E	-	-	-	Amino Acid
MAKDMGGG_01337	5.7e-62	potE	-	-	E	-	-	-	Amino Acid
MAKDMGGG_01338	1.75e-197	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MAKDMGGG_01339	1.42e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MAKDMGGG_01340	2.53e-42	-	-	-	-	-	-	-	-
MAKDMGGG_01341	3.73e-171	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MAKDMGGG_01342	3.17e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MAKDMGGG_01343	8.95e-222	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MAKDMGGG_01344	8.21e-135	-	-	-	M	-	-	-	Bacterial sugar transferase
MAKDMGGG_01345	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
MAKDMGGG_01346	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
MAKDMGGG_01347	6.94e-167	-	-	-	F	-	-	-	glutamine amidotransferase
MAKDMGGG_01348	1.32e-80	-	-	-	-	-	-	-	-
MAKDMGGG_01349	4.5e-202	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MAKDMGGG_01350	2.4e-180	-	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_01351	9.44e-234	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MAKDMGGG_01352	3.11e-209	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MAKDMGGG_01353	1.94e-290	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
MAKDMGGG_01354	1.32e-222	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKDMGGG_01355	1.63e-193	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
MAKDMGGG_01356	3.91e-111	-	-	-	S	-	-	-	Alpha beta hydrolase
MAKDMGGG_01357	7.07e-83	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MAKDMGGG_01358	6.16e-126	epsB	-	-	M	-	-	-	biosynthesis protein
MAKDMGGG_01359	3.01e-140	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MAKDMGGG_01360	2.35e-62	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
MAKDMGGG_01361	3.03e-104	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
MAKDMGGG_01362	8.32e-82	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
MAKDMGGG_01363	3.16e-49	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
MAKDMGGG_01365	1.2e-83	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MAKDMGGG_01366	1.11e-32	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MAKDMGGG_01367	2.57e-35	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
MAKDMGGG_01368	5.75e-05	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
MAKDMGGG_01369	2.2e-07	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MAKDMGGG_01371	1.21e-296	-	-	-	S	-	-	-	amidohydrolase
MAKDMGGG_01372	1.26e-24	-	-	-	S	-	-	-	amidohydrolase
MAKDMGGG_01373	8.44e-70	-	-	-	K	-	-	-	LysR substrate binding domain
MAKDMGGG_01375	1.57e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MAKDMGGG_01377	2.62e-203	-	-	-	S	-	-	-	reductase
MAKDMGGG_01378	9.23e-116	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
MAKDMGGG_01379	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MAKDMGGG_01380	1.04e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MAKDMGGG_01381	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MAKDMGGG_01382	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MAKDMGGG_01383	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MAKDMGGG_01384	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MAKDMGGG_01385	9.93e-167	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
MAKDMGGG_01386	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MAKDMGGG_01387	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MAKDMGGG_01388	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MAKDMGGG_01389	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MAKDMGGG_01390	8.13e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MAKDMGGG_01391	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MAKDMGGG_01392	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MAKDMGGG_01393	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAKDMGGG_01394	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MAKDMGGG_01395	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MAKDMGGG_01396	2.82e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MAKDMGGG_01397	1.28e-45	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MAKDMGGG_01398	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MAKDMGGG_01399	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MAKDMGGG_01400	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MAKDMGGG_01401	6.51e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_01402	9.43e-73	-	-	-	-	-	-	-	-
MAKDMGGG_01403	1.78e-208	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
MAKDMGGG_01404	9.78e-16	-	-	-	-	-	-	-	-
MAKDMGGG_01405	2.74e-26	-	-	-	-	-	-	-	-
MAKDMGGG_01406	9.21e-99	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MAKDMGGG_01407	2.01e-62	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAKDMGGG_01408	3.22e-22	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKDMGGG_01413	3.83e-33	-	-	-	S	-	-	-	Siphovirus Gp157
MAKDMGGG_01414	1.41e-200	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAKDMGGG_01415	1.49e-111	-	-	-	L	-	-	-	AAA domain
MAKDMGGG_01416	7.5e-43	-	-	-	-	-	-	-	-
MAKDMGGG_01417	4.42e-105	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
MAKDMGGG_01418	5.39e-150	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
MAKDMGGG_01420	2.13e-77	-	-	-	S	-	-	-	VRR_NUC
MAKDMGGG_01422	1.11e-30	-	-	-	-	-	-	-	-
MAKDMGGG_01424	6.41e-101	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKDMGGG_01425	1.16e-41	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MAKDMGGG_01426	4.34e-70	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01427	1.01e-52	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01428	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MAKDMGGG_01429	6.01e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MAKDMGGG_01430	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
MAKDMGGG_01431	3.71e-316	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MAKDMGGG_01432	3.06e-198	menH	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MAKDMGGG_01433	3.83e-260	-	-	-	G	-	-	-	Major Facilitator Superfamily
MAKDMGGG_01434	1.69e-259	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MAKDMGGG_01435	1.02e-294	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MAKDMGGG_01436	1.12e-102	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MAKDMGGG_01437	1.13e-163	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MAKDMGGG_01438	1.36e-135	yocS	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
MAKDMGGG_01439	4.53e-66	isp	-	-	L	-	-	-	Transposase
MAKDMGGG_01440	1.56e-96	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
MAKDMGGG_01441	4.43e-43	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
MAKDMGGG_01442	1.22e-144	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
MAKDMGGG_01443	3.96e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MAKDMGGG_01444	1.09e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
MAKDMGGG_01445	2.25e-45	-	-	-	C	-	-	-	Heavy-metal-associated domain
MAKDMGGG_01446	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
MAKDMGGG_01447	2.16e-105	-	-	-	-	-	-	-	-
MAKDMGGG_01448	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MAKDMGGG_01449	1.64e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MAKDMGGG_01450	3.96e-110	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MAKDMGGG_01451	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
MAKDMGGG_01452	1.63e-209	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MAKDMGGG_01453	2.97e-124	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MAKDMGGG_01454	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MAKDMGGG_01455	4.4e-309	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MAKDMGGG_01456	9.82e-85	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MAKDMGGG_01457	2.59e-175	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MAKDMGGG_01458	2.41e-179	-	-	-	S	-	-	-	Membrane
MAKDMGGG_01459	4.73e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
MAKDMGGG_01460	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MAKDMGGG_01461	1.9e-146	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MAKDMGGG_01462	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MAKDMGGG_01463	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MAKDMGGG_01464	2.98e-104	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
MAKDMGGG_01465	0.0	-	-	-	E	-	-	-	amino acid
MAKDMGGG_01468	1.16e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MAKDMGGG_01469	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
MAKDMGGG_01470	1.58e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MAKDMGGG_01471	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MAKDMGGG_01472	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
MAKDMGGG_01473	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MAKDMGGG_01474	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
MAKDMGGG_01475	2.25e-47	-	-	-	S	-	-	-	ASCH
MAKDMGGG_01476	3.53e-123	-	-	-	K	-	-	-	acetyltransferase
MAKDMGGG_01477	2.22e-108	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MAKDMGGG_01482	8.97e-171	-	-	-	-	-	-	-	-
MAKDMGGG_01483	8.03e-92	-	-	-	-	-	-	-	-
MAKDMGGG_01485	2.41e-174	-	-	-	L	-	-	-	DnaD domain protein
MAKDMGGG_01488	1.62e-26	-	-	-	-	-	-	-	-
MAKDMGGG_01489	1.46e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MAKDMGGG_01490	3.14e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
MAKDMGGG_01492	3.17e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MAKDMGGG_01493	3.08e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MAKDMGGG_01494	1.4e-69	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MAKDMGGG_01495	8.37e-242	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MAKDMGGG_01496	9.53e-317	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MAKDMGGG_01497	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MAKDMGGG_01498	5.23e-101	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MAKDMGGG_01499	8.05e-117	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MAKDMGGG_01500	1.73e-218	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MAKDMGGG_01501	7.71e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MAKDMGGG_01502	1.91e-196	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MAKDMGGG_01503	6.23e-188	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MAKDMGGG_01504	4.9e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MAKDMGGG_01505	1.84e-75	-	-	-	-	-	-	-	-
MAKDMGGG_01506	4.92e-266	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MAKDMGGG_01507	2.41e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MAKDMGGG_01508	5.47e-105	-	-	-	-	-	-	-	-
MAKDMGGG_01509	9.03e-55	-	-	-	-	-	-	-	-
MAKDMGGG_01510	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MAKDMGGG_01511	3.28e-232	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MAKDMGGG_01512	3.15e-12	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
MAKDMGGG_01513	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MAKDMGGG_01515	2.3e-150	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MAKDMGGG_01517	6.02e-156	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MAKDMGGG_01518	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
MAKDMGGG_01519	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MAKDMGGG_01520	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MAKDMGGG_01521	6.15e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MAKDMGGG_01522	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MAKDMGGG_01523	1.24e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAKDMGGG_01524	1.54e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MAKDMGGG_01525	5.21e-275	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MAKDMGGG_01526	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKDMGGG_01527	3.01e-168	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01528	4.28e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MAKDMGGG_01529	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MAKDMGGG_01530	7.17e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MAKDMGGG_01531	1.12e-64	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MAKDMGGG_01532	1.69e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MAKDMGGG_01533	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MAKDMGGG_01534	2.44e-265	yacL	-	-	S	-	-	-	domain protein
MAKDMGGG_01535	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKDMGGG_01536	8.79e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MAKDMGGG_01537	2.37e-48	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAKDMGGG_01538	8.61e-88	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MAKDMGGG_01539	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MAKDMGGG_01540	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MAKDMGGG_01541	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MAKDMGGG_01542	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MAKDMGGG_01543	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MAKDMGGG_01544	5.57e-290	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
MAKDMGGG_01546	1.2e-298	-	-	-	M	-	-	-	Glycosyl transferase family group 2
MAKDMGGG_01547	2e-264	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MAKDMGGG_01548	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MAKDMGGG_01549	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MAKDMGGG_01550	3.4e-64	-	-	-	-	-	-	-	-
MAKDMGGG_01552	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MAKDMGGG_01553	9.71e-76	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
MAKDMGGG_01554	1.17e-121	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
MAKDMGGG_01555	3.67e-176	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MAKDMGGG_01556	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MAKDMGGG_01558	4.99e-98	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
MAKDMGGG_01559	7.27e-83	-	-	-	S	-	-	-	Glycosyltransferase like family
MAKDMGGG_01560	1.56e-95	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
MAKDMGGG_01561	9.63e-38	-	-	-	M	-	-	-	biosynthesis protein
MAKDMGGG_01562	1.35e-44	-	-	-	-	-	-	-	-
MAKDMGGG_01563	1.69e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MAKDMGGG_01564	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MAKDMGGG_01565	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MAKDMGGG_01566	1.4e-63	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MAKDMGGG_01567	1e-270	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MAKDMGGG_01569	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MAKDMGGG_01570	2.39e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MAKDMGGG_01571	8.57e-114	-	-	-	-	-	-	-	-
MAKDMGGG_01572	9.3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MAKDMGGG_01573	3.01e-274	yttB	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_01574	2.83e-144	-	-	-	-	-	-	-	-
MAKDMGGG_01575	2.6e-33	-	-	-	-	-	-	-	-
MAKDMGGG_01576	2.74e-139	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKDMGGG_01577	4.97e-40	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKDMGGG_01579	2.6e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MAKDMGGG_01580	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MAKDMGGG_01581	1.16e-315	yycH	-	-	S	-	-	-	YycH protein
MAKDMGGG_01582	5.03e-193	yycI	-	-	S	-	-	-	YycH protein
MAKDMGGG_01583	2.94e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MAKDMGGG_01584	2.46e-289	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MAKDMGGG_01585	9.62e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
MAKDMGGG_01586	8.65e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MAKDMGGG_01587	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MAKDMGGG_01588	2.03e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MAKDMGGG_01589	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MAKDMGGG_01590	2.39e-186	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MAKDMGGG_01591	3.57e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
MAKDMGGG_01592	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MAKDMGGG_01593	7.38e-146	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAKDMGGG_01594	4.65e-184	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MAKDMGGG_01595	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MAKDMGGG_01596	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MAKDMGGG_01597	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MAKDMGGG_01598	2.09e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MAKDMGGG_01599	3.85e-90	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MAKDMGGG_01600	4.78e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MAKDMGGG_01601	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MAKDMGGG_01602	1.94e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MAKDMGGG_01603	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MAKDMGGG_01604	8.24e-229	-	-	-	-	-	-	-	-
MAKDMGGG_01605	9.52e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MAKDMGGG_01606	7.08e-161	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
MAKDMGGG_01607	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
MAKDMGGG_01608	2.84e-306	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MAKDMGGG_01609	1.08e-23	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
MAKDMGGG_01610	1.88e-57	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
MAKDMGGG_01611	0.0	-	-	-	G	-	-	-	Right handed beta helix region
MAKDMGGG_01612	1.26e-223	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MAKDMGGG_01613	3.92e-87	-	-	-	S	-	-	-	glycosyl transferase family 2
MAKDMGGG_01614	0.0	-	-	-	M	-	-	-	family 8
MAKDMGGG_01615	0.0	-	-	-	L	-	-	-	Transposase
MAKDMGGG_01616	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
MAKDMGGG_01617	1.05e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MAKDMGGG_01618	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MAKDMGGG_01619	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MAKDMGGG_01620	6.92e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MAKDMGGG_01621	7.19e-244	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MAKDMGGG_01622	4.4e-72	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MAKDMGGG_01623	2e-199	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MAKDMGGG_01624	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MAKDMGGG_01625	3e-221	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MAKDMGGG_01626	2.02e-269	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MAKDMGGG_01627	2.84e-109	flp	-	-	V	-	-	-	Beta-lactamase
MAKDMGGG_01628	2.25e-70	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MAKDMGGG_01629	3.45e-205	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
MAKDMGGG_01630	1.67e-107	-	-	-	C	-	-	-	Flavodoxin
MAKDMGGG_01631	1.19e-200	lysR	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_01632	1.32e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
MAKDMGGG_01633	4.85e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKDMGGG_01634	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MAKDMGGG_01635	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MAKDMGGG_01636	1.81e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MAKDMGGG_01637	1.72e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MAKDMGGG_01638	2.13e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MAKDMGGG_01639	2.37e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MAKDMGGG_01640	1.65e-125	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MAKDMGGG_01641	1.32e-139	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MAKDMGGG_01642	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MAKDMGGG_01643	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MAKDMGGG_01644	5.44e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MAKDMGGG_01645	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MAKDMGGG_01646	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MAKDMGGG_01647	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
MAKDMGGG_01648	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MAKDMGGG_01649	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MAKDMGGG_01650	1.75e-35	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAKDMGGG_01651	2.61e-137	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MAKDMGGG_01652	2.23e-36	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MAKDMGGG_01653	1.19e-137	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MAKDMGGG_01654	1.26e-84	-	-	-	-	-	-	-	-
MAKDMGGG_01655	4.58e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MAKDMGGG_01656	8.1e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MAKDMGGG_01657	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MAKDMGGG_01658	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MAKDMGGG_01659	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MAKDMGGG_01660	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKDMGGG_01661	4.3e-256	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
MAKDMGGG_01662	4.21e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MAKDMGGG_01663	2.81e-177	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MAKDMGGG_01664	8.1e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MAKDMGGG_01665	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MAKDMGGG_01666	3.48e-94	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MAKDMGGG_01667	2e-216	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MAKDMGGG_01668	6.13e-233	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MAKDMGGG_01669	7.1e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MAKDMGGG_01670	7.06e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MAKDMGGG_01671	2.63e-19	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MAKDMGGG_01672	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MAKDMGGG_01673	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
MAKDMGGG_01674	4.99e-58	-	-	-	-	-	-	-	-
MAKDMGGG_01675	8.95e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
MAKDMGGG_01676	9.84e-184	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MAKDMGGG_01677	5.54e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MAKDMGGG_01678	9.97e-152	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MAKDMGGG_01679	8.68e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MAKDMGGG_01680	2.05e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MAKDMGGG_01681	6.57e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MAKDMGGG_01682	1.76e-147	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MAKDMGGG_01683	1.29e-37	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MAKDMGGG_01684	1.07e-88	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAKDMGGG_01685	1.48e-64	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MAKDMGGG_01686	1.08e-13	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAKDMGGG_01687	9.96e-19	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MAKDMGGG_01688	6.13e-191	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MAKDMGGG_01689	9.08e-153	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MAKDMGGG_01690	3.88e-42	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MAKDMGGG_01691	9.22e-73	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MAKDMGGG_01692	1.19e-135	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MAKDMGGG_01693	1.42e-103	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MAKDMGGG_01694	7.04e-173	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MAKDMGGG_01695	2.11e-19	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MAKDMGGG_01696	3.51e-132	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MAKDMGGG_01698	1.02e-75	-	-	-	S	-	-	-	VRR_NUC
MAKDMGGG_01700	7.95e-288	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
MAKDMGGG_01701	5.66e-186	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
MAKDMGGG_01702	2.84e-120	-	-	-	-	-	-	-	-
MAKDMGGG_01703	2.13e-181	-	-	-	L	-	-	-	AAA domain
MAKDMGGG_01704	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MAKDMGGG_01705	2.12e-107	-	-	-	S	-	-	-	Siphovirus Gp157
MAKDMGGG_01708	4.11e-35	-	-	-	-	-	-	-	-
MAKDMGGG_01711	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MAKDMGGG_01712	2.14e-195	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAKDMGGG_01713	1.31e-69	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MAKDMGGG_01714	5.26e-260	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MAKDMGGG_01715	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MAKDMGGG_01716	4.7e-282	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
MAKDMGGG_01718	5.58e-70	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAKDMGGG_01719	1.21e-64	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MAKDMGGG_01720	2.41e-196	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MAKDMGGG_01721	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MAKDMGGG_01722	5.25e-215	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
MAKDMGGG_01723	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MAKDMGGG_01724	1.14e-279	arcT	-	-	E	-	-	-	Aminotransferase
MAKDMGGG_01725	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MAKDMGGG_01726	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MAKDMGGG_01727	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MAKDMGGG_01728	1.42e-72	-	-	-	-	-	-	-	-
MAKDMGGG_01729	2.34e-263	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MAKDMGGG_01731	2.65e-17	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MAKDMGGG_01732	2.12e-14	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MAKDMGGG_01733	7.78e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MAKDMGGG_01734	4.52e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MAKDMGGG_01735	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MAKDMGGG_01736	2.79e-75	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MAKDMGGG_01737	1.11e-204	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MAKDMGGG_01738	7.67e-143	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
MAKDMGGG_01739	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
MAKDMGGG_01740	3.06e-199	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MAKDMGGG_01742	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKDMGGG_01743	3.66e-93	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MAKDMGGG_01744	2.38e-289	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MAKDMGGG_01745	1.1e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MAKDMGGG_01746	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MAKDMGGG_01747	1.11e-106	-	-	-	-	-	-	-	-
MAKDMGGG_01748	7.13e-31	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MAKDMGGG_01749	1.62e-263	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MAKDMGGG_01750	5.85e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MAKDMGGG_01751	1.65e-42	-	-	-	-	-	-	-	-
MAKDMGGG_01752	2.39e-289	-	-	-	G	-	-	-	Peptidase_C39 like family
MAKDMGGG_01753	1.03e-72	-	-	-	-	-	-	-	-
MAKDMGGG_01754	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MAKDMGGG_01756	1.79e-42	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MAKDMGGG_01757	2.16e-28	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MAKDMGGG_01758	1.21e-132	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MAKDMGGG_01759	3.01e-273	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
MAKDMGGG_01760	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MAKDMGGG_01761	1.03e-19	-	-	-	-	-	-	-	-
MAKDMGGG_01762	4.23e-28	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MAKDMGGG_01763	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MAKDMGGG_01764	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MAKDMGGG_01765	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MAKDMGGG_01766	3.83e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MAKDMGGG_01767	5.73e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MAKDMGGG_01768	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MAKDMGGG_01770	1.83e-21	-	-	-	-	-	-	-	-
MAKDMGGG_01771	3.11e-297	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
MAKDMGGG_01772	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MAKDMGGG_01774	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MAKDMGGG_01775	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MAKDMGGG_01776	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MAKDMGGG_01777	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MAKDMGGG_01778	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MAKDMGGG_01779	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKDMGGG_01780	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MAKDMGGG_01781	4e-188	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
MAKDMGGG_01782	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MAKDMGGG_01783	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MAKDMGGG_01784	5.56e-136	-	-	-	-	-	-	-	-
MAKDMGGG_01785	7.51e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MAKDMGGG_01786	1.97e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MAKDMGGG_01787	1.71e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MAKDMGGG_01788	6.2e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAKDMGGG_01789	3.99e-96	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MAKDMGGG_01790	4.86e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MAKDMGGG_01791	3.94e-167	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MAKDMGGG_01792	1.15e-315	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MAKDMGGG_01793	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MAKDMGGG_01794	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01795	2.15e-286	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAKDMGGG_01796	3.98e-180	-	-	-	S	-	-	-	Phage Mu protein F like protein
MAKDMGGG_01797	2.58e-260	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MAKDMGGG_01798	4.71e-301	yqaT	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
MAKDMGGG_01799	8.89e-86	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
MAKDMGGG_01801	1.01e-18	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MAKDMGGG_01802	8.15e-250	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MAKDMGGG_01803	1.27e-250	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MAKDMGGG_01804	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MAKDMGGG_01806	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MAKDMGGG_01807	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MAKDMGGG_01808	6.55e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MAKDMGGG_01809	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MAKDMGGG_01810	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MAKDMGGG_01811	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKDMGGG_01812	1.9e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKDMGGG_01813	2.94e-46	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MAKDMGGG_01814	4.3e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MAKDMGGG_01815	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MAKDMGGG_01816	3.15e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MAKDMGGG_01817	4.26e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MAKDMGGG_01818	4.28e-128	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MAKDMGGG_01819	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MAKDMGGG_01820	1.26e-232	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MAKDMGGG_01821	4.79e-161	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
MAKDMGGG_01822	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MAKDMGGG_01823	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MAKDMGGG_01824	1.09e-73	ydbI	-	-	K	-	-	-	AI-2E family transporter
MAKDMGGG_01825	1.78e-107	ydbI	-	-	K	-	-	-	AI-2E family transporter
MAKDMGGG_01826	2.33e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MAKDMGGG_01827	8.03e-143	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MAKDMGGG_01828	2.61e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MAKDMGGG_01829	7.97e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MAKDMGGG_01830	6.52e-219	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MAKDMGGG_01831	1.44e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MAKDMGGG_01832	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MAKDMGGG_01833	1.97e-179	-	-	-	K	-	-	-	LysR substrate binding domain
MAKDMGGG_01834	9.94e-71	-	-	-	S	-	-	-	branched-chain amino acid
MAKDMGGG_01835	7.65e-183	-	-	-	E	-	-	-	AzlC protein
MAKDMGGG_01836	8.95e-273	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKDMGGG_01837	1.72e-25	-	-	-	-	-	-	-	-
MAKDMGGG_01838	6.42e-35	-	-	-	S	-	-	-	Bacterial PH domain
MAKDMGGG_01839	1.75e-21	-	-	-	E	-	-	-	Zn peptidase
MAKDMGGG_01840	8.81e-19	-	-	-	K	-	-	-	Peptidase S24-like
MAKDMGGG_01842	4.29e-51	-	-	-	-	-	-	-	-
MAKDMGGG_01843	3.98e-277	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
MAKDMGGG_01844	2.03e-219	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MAKDMGGG_01845	2.43e-207	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MAKDMGGG_01846	1.62e-34	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MAKDMGGG_01847	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
MAKDMGGG_01848	2.1e-31	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MAKDMGGG_01849	7.28e-292	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MAKDMGGG_01850	1.01e-170	-	-	-	O	-	-	-	Bacterial dnaA protein
MAKDMGGG_01851	6.41e-302	-	-	-	L	-	-	-	Integrase core domain
MAKDMGGG_01852	5.1e-51	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MAKDMGGG_01853	1.06e-104	-	-	-	S	-	-	-	Cupin domain
MAKDMGGG_01854	6.68e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
MAKDMGGG_01855	4.59e-306	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MAKDMGGG_01856	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
MAKDMGGG_01857	1.05e-160	yhdP	-	-	S	-	-	-	Transporter associated domain
MAKDMGGG_01858	5.92e-76	-	-	-	-	-	-	-	-
MAKDMGGG_01859	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MAKDMGGG_01860	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MAKDMGGG_01861	2.17e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MAKDMGGG_01862	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MAKDMGGG_01863	1.43e-160	ybbR	-	-	S	-	-	-	YbbR-like protein
MAKDMGGG_01864	4.28e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MAKDMGGG_01865	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
MAKDMGGG_01866	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MAKDMGGG_01867	3.08e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MAKDMGGG_01868	2.36e-164	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
MAKDMGGG_01869	6.24e-270	-	-	-	L	-	-	-	Integrase core domain
MAKDMGGG_01870	2.54e-243	mocA	-	-	S	-	-	-	Oxidoreductase
MAKDMGGG_01871	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
MAKDMGGG_01872	2.83e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MAKDMGGG_01873	1.45e-86	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKDMGGG_01874	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MAKDMGGG_01875	6.96e-244	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
MAKDMGGG_01876	4.19e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
MAKDMGGG_01878	1.42e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MAKDMGGG_01879	3.73e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MAKDMGGG_01880	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MAKDMGGG_01881	1.52e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
MAKDMGGG_01883	1.49e-45	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MAKDMGGG_01884	1.51e-88	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MAKDMGGG_01885	3.66e-226	-	-	-	-	-	-	-	-
MAKDMGGG_01886	3.92e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MAKDMGGG_01887	1.03e-213	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MAKDMGGG_01888	2.26e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKDMGGG_01889	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
MAKDMGGG_01890	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
MAKDMGGG_01891	0.0	-	-	-	L	-	-	-	DNA helicase
MAKDMGGG_01892	4.11e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MAKDMGGG_01893	2.47e-250	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKDMGGG_01894	2.48e-49	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
MAKDMGGG_01896	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MAKDMGGG_01897	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MAKDMGGG_01898	1.91e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MAKDMGGG_01899	5.98e-55	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
MAKDMGGG_01900	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
MAKDMGGG_01901	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MAKDMGGG_01902	4.65e-195	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MAKDMGGG_01903	2.44e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MAKDMGGG_01904	1.06e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MAKDMGGG_01905	6.29e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MAKDMGGG_01906	1.5e-102	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MAKDMGGG_01907	3.69e-92	-	-	-	-	-	-	-	-
MAKDMGGG_01908	2.78e-131	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MAKDMGGG_01909	1.13e-157	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MAKDMGGG_01910	2.67e-187	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MAKDMGGG_01912	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MAKDMGGG_01913	1.1e-125	-	-	-	S	-	-	-	reductase
MAKDMGGG_01914	8.48e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
MAKDMGGG_01915	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MAKDMGGG_01916	1.56e-213	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MAKDMGGG_01917	2.17e-188	epsB	-	-	M	-	-	-	biosynthesis protein
MAKDMGGG_01918	6.05e-153	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MAKDMGGG_01919	3.74e-134	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
MAKDMGGG_01923	6.03e-79	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MAKDMGGG_01924	4.94e-23	-	-	-	-	-	-	-	-
MAKDMGGG_01927	1.84e-41	-	-	-	V	-	-	-	NUMOD4 motif
MAKDMGGG_01930	2.44e-20	-	-	-	-	-	-	-	-
MAKDMGGG_01931	1.41e-23	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
MAKDMGGG_01932	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MAKDMGGG_01933	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MAKDMGGG_01934	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MAKDMGGG_01935	4.06e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MAKDMGGG_01936	8.25e-179	-	-	-	S	-	-	-	Tetratricopeptide repeat
MAKDMGGG_01937	7.26e-146	-	-	-	S	-	-	-	Membrane
MAKDMGGG_01938	2.9e-157	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
MAKDMGGG_01939	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MAKDMGGG_01940	9.88e-229	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
MAKDMGGG_01941	4.39e-170	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
MAKDMGGG_01942	6.68e-37	-	-	-	-	-	-	-	-
MAKDMGGG_01943	4.03e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MAKDMGGG_01944	7.99e-228	-	-	-	S	-	-	-	Peptidase, M23
MAKDMGGG_01945	3.94e-45	-	-	-	-	-	-	-	-
MAKDMGGG_01946	2.58e-71	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
MAKDMGGG_01947	2.17e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MAKDMGGG_01948	1.43e-105	-	-	-	-	-	-	-	-
MAKDMGGG_01949	1.44e-80	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MAKDMGGG_01950	1.5e-40	-	-	-	-	-	-	-	-
MAKDMGGG_01951	7.67e-63	-	-	-	-	-	-	-	-
MAKDMGGG_01952	3.42e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MAKDMGGG_01953	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MAKDMGGG_01954	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MAKDMGGG_01955	3.95e-167	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MAKDMGGG_01956	2.85e-114	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MAKDMGGG_01957	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKDMGGG_01958	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MAKDMGGG_01959	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_01960	5.52e-240	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MAKDMGGG_01961	6.91e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MAKDMGGG_01962	2.34e-187	-	-	-	-	-	-	-	-
MAKDMGGG_01963	2.34e-203	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MAKDMGGG_01964	3.95e-238	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
MAKDMGGG_01965	1.28e-171	XK27_07210	-	-	S	-	-	-	B3 4 domain
MAKDMGGG_01966	1.93e-101	yybA	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_01967	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MAKDMGGG_01968	1.63e-116	-	-	-	GM	-	-	-	epimerase
MAKDMGGG_01969	4.86e-199	-	-	-	V	-	-	-	(ABC) transporter
MAKDMGGG_01970	1.23e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
MAKDMGGG_01971	7.61e-58	yhdP	-	-	S	-	-	-	Transporter associated domain
MAKDMGGG_01972	1.37e-67	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MAKDMGGG_01973	4.3e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
MAKDMGGG_01974	5.09e-244	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
MAKDMGGG_01975	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MAKDMGGG_01976	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MAKDMGGG_01977	4.85e-52	-	-	-	-	-	-	-	-
MAKDMGGG_01978	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MAKDMGGG_01979	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
MAKDMGGG_01980	3.33e-296	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
MAKDMGGG_01981	6.7e-239	isp	-	-	L	-	-	-	Transposase
MAKDMGGG_01982	1.17e-22	isp	-	-	L	-	-	-	Transposase
MAKDMGGG_01983	5.35e-176	-	-	-	V	-	-	-	Beta-lactamase enzyme family
MAKDMGGG_01984	2.74e-285	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MAKDMGGG_01985	6.26e-96	-	-	-	-	-	-	-	-
MAKDMGGG_01987	2.1e-174	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKDMGGG_01989	4.77e-65	yrvD	-	-	S	-	-	-	Pfam:DUF1049
MAKDMGGG_01990	1.78e-26	-	-	-	-	-	-	-	-
MAKDMGGG_01993	5.43e-101	-	-	-	K	-	-	-	Peptidase S24-like
MAKDMGGG_01994	1.21e-19	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
MAKDMGGG_01999	3.25e-08	-	-	-	S	-	-	-	Helix-turn-helix domain
MAKDMGGG_02000	0.000772	-	-	-	L	-	-	-	GIY-YIG catalytic domain
MAKDMGGG_02001	1.09e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKDMGGG_02002	3.77e-123	-	-	-	-	-	-	-	-
MAKDMGGG_02003	8.44e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MAKDMGGG_02004	2.62e-165	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MAKDMGGG_02005	1.85e-18	yjbH	-	-	Q	-	-	-	Thioredoxin
MAKDMGGG_02006	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MAKDMGGG_02007	1.46e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MAKDMGGG_02008	4.11e-223	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MAKDMGGG_02011	8.53e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MAKDMGGG_02012	1.78e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MAKDMGGG_02013	6.07e-77	-	-	-	S	-	-	-	macrophage migration inhibitory factor
MAKDMGGG_02014	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MAKDMGGG_02017	2.88e-47	-	-	-	S	-	-	-	Bacteriophage holin family
MAKDMGGG_02018	2.59e-71	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MAKDMGGG_02020	3.36e-83	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
MAKDMGGG_02021	9.43e-316	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MAKDMGGG_02023	2.82e-11	-	-	-	K	-	-	-	LytTr DNA-binding domain
MAKDMGGG_02024	1.07e-72	-	-	-	-	-	-	-	-
MAKDMGGG_02025	1.57e-94	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MAKDMGGG_02026	2.3e-36	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MAKDMGGG_02027	1.42e-31	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MAKDMGGG_02028	1.07e-276	-	-	-	E	-	-	-	amino acid
MAKDMGGG_02029	1.19e-175	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MAKDMGGG_02030	3.4e-311	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MAKDMGGG_02031	3.76e-214	-	-	-	GK	-	-	-	ROK family
MAKDMGGG_02032	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MAKDMGGG_02033	4.32e-105	uspA3	-	-	T	-	-	-	universal stress protein
MAKDMGGG_02034	8.24e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MAKDMGGG_02035	1.78e-83	-	-	-	-	-	-	-	-
MAKDMGGG_02036	3.18e-11	-	-	-	-	-	-	-	-
MAKDMGGG_02037	2.34e-151	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MAKDMGGG_02038	1.59e-175	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MAKDMGGG_02039	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_02040	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MAKDMGGG_02041	8.78e-95	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MAKDMGGG_02042	2.08e-26	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MAKDMGGG_02043	5.48e-20	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MAKDMGGG_02044	1.65e-205	-	-	-	-	-	-	-	-
MAKDMGGG_02045	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_02046	9.17e-229	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MAKDMGGG_02047	1.38e-63	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MAKDMGGG_02048	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MAKDMGGG_02049	6.5e-71	-	-	-	-	-	-	-	-
MAKDMGGG_02050	3.54e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MAKDMGGG_02051	2.71e-316	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_02052	5.18e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MAKDMGGG_02053	1.03e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MAKDMGGG_02054	4.29e-175	-	-	-	IQ	-	-	-	KR domain
MAKDMGGG_02055	1.1e-232	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MAKDMGGG_02056	1.89e-230	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MAKDMGGG_02057	1.06e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
MAKDMGGG_02058	2.05e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MAKDMGGG_02059	8.04e-257	snf	-	-	KL	-	-	-	domain protein
MAKDMGGG_02060	2.93e-116	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKDMGGG_02062	4.68e-28	-	-	-	-	-	-	-	-
MAKDMGGG_02063	7.45e-116	yjbH	-	-	Q	-	-	-	Thioredoxin
MAKDMGGG_02064	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKDMGGG_02065	2.56e-149	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MAKDMGGG_02066	4.82e-164	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MAKDMGGG_02067	7.2e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MAKDMGGG_02068	5.08e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MAKDMGGG_02069	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MAKDMGGG_02070	5.7e-146	-	-	-	K	-	-	-	Transcriptional regulator
MAKDMGGG_02074	1.93e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
MAKDMGGG_02075	1.26e-224	-	-	-	-	-	-	-	-
MAKDMGGG_02076	1.39e-179	-	-	-	-	-	-	-	-
MAKDMGGG_02077	2.73e-302	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MAKDMGGG_02078	1.4e-196	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MAKDMGGG_02079	6.71e-147	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MAKDMGGG_02080	4.96e-152	flp	-	-	V	-	-	-	Beta-lactamase
MAKDMGGG_02081	2.84e-94	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MAKDMGGG_02082	6.28e-116	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MAKDMGGG_02083	4.29e-26	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
MAKDMGGG_02084	3.78e-88	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MAKDMGGG_02085	1.74e-164	-	-	-	-	-	-	-	-
MAKDMGGG_02086	1e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MAKDMGGG_02087	1.61e-48	-	-	-	-	-	-	-	-
MAKDMGGG_02088	3.78e-219	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MAKDMGGG_02089	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MAKDMGGG_02090	1.46e-29	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MAKDMGGG_02091	8.96e-24	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MAKDMGGG_02104	2.36e-167	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKDMGGG_02106	3.51e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MAKDMGGG_02107	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MAKDMGGG_02108	2.51e-109	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MAKDMGGG_02109	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MAKDMGGG_02110	8.42e-55	-	-	-	-	-	-	-	-
MAKDMGGG_02111	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MAKDMGGG_02112	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MAKDMGGG_02113	3.41e-125	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MAKDMGGG_02114	0.0	-	-	-	EGP	-	-	-	Major Facilitator
MAKDMGGG_02115	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MAKDMGGG_02116	9.52e-301	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MAKDMGGG_02117	1.37e-133	-	-	-	V	-	-	-	VanZ like family
MAKDMGGG_02118	4.78e-31	-	-	-	-	-	-	-	-
MAKDMGGG_02119	4.13e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MAKDMGGG_02120	9.25e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MAKDMGGG_02121	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
MAKDMGGG_02122	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MAKDMGGG_02123	3.69e-196	yeaE	-	-	S	-	-	-	Aldo keto
MAKDMGGG_02124	3.25e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MAKDMGGG_02125	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MAKDMGGG_02126	2.95e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MAKDMGGG_02127	1.82e-130	-	-	-	M	-	-	-	LysM domain protein
MAKDMGGG_02128	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
MAKDMGGG_02129	1.73e-151	-	-	-	M	-	-	-	LysM domain protein
MAKDMGGG_02130	1.68e-199	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
MAKDMGGG_02131	1.09e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MAKDMGGG_02132	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MAKDMGGG_02136	1.18e-50	-	-	-	-	-	-	-	-
MAKDMGGG_02139	1.05e-57	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MAKDMGGG_02140	7.06e-35	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MAKDMGGG_02141	1.26e-169	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
MAKDMGGG_02142	7.27e-38	-	-	-	-	-	-	-	-
MAKDMGGG_02143	1.84e-234	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MAKDMGGG_02145	1.25e-74	-	-	-	-	-	-	-	-
MAKDMGGG_02146	2.07e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MAKDMGGG_02147	2.12e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MAKDMGGG_02148	7.98e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MAKDMGGG_02149	3.14e-147	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MAKDMGGG_02150	2.96e-71	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MAKDMGGG_02151	8.58e-159	-	-	-	L	-	-	-	Helix-turn-helix domain
MAKDMGGG_02152	1.41e-205	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MAKDMGGG_02153	6.01e-17	XK27_09155	-	-	K	-	-	-	Transcriptional
MAKDMGGG_02154	2.42e-116	-	-	-	L	-	-	-	Integrase
MAKDMGGG_02155	3.5e-112	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MAKDMGGG_02156	1.57e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MAKDMGGG_02157	3.93e-119	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MAKDMGGG_02159	1.11e-66	-	-	-	-	-	-	-	-
MAKDMGGG_02160	3.67e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MAKDMGGG_02161	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MAKDMGGG_02162	2.38e-93	-	-	-	L	-	-	-	Phage terminase, small subunit
MAKDMGGG_02163	1.85e-193	-	-	-	L	-	-	-	HNH nucleases
MAKDMGGG_02165	2.21e-27	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MAKDMGGG_02166	6.21e-51	-	-	-	M	-	-	-	Sortase family
MAKDMGGG_02167	6.85e-95	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
MAKDMGGG_02168	2.3e-165	-	-	-	M	-	-	-	PFAM NLP P60 protein
MAKDMGGG_02169	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MAKDMGGG_02170	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MAKDMGGG_02171	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MAKDMGGG_02172	7.02e-122	-	-	-	P	-	-	-	Cadmium resistance transporter
MAKDMGGG_02173	2.29e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MAKDMGGG_02174	2.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MAKDMGGG_02175	1.08e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
MAKDMGGG_02176	4.59e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MAKDMGGG_02177	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MAKDMGGG_02178	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MAKDMGGG_02179	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MAKDMGGG_02180	3.99e-315	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MAKDMGGG_02181	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MAKDMGGG_02182	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
MAKDMGGG_02183	1.64e-26	-	-	-	-	-	-	-	-
MAKDMGGG_02184	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MAKDMGGG_02185	3.46e-265	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
MAKDMGGG_02186	8.55e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
MAKDMGGG_02187	6.32e-274	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MAKDMGGG_02188	2.53e-127	-	-	-	-	-	-	-	-
MAKDMGGG_02190	6.67e-158	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MAKDMGGG_02191	1.55e-102	bioA	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MAKDMGGG_02193	3.45e-88	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MAKDMGGG_02194	9.67e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MAKDMGGG_02195	4.45e-185	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
MAKDMGGG_02196	1.94e-46	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
MAKDMGGG_02197	2.95e-52	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
MAKDMGGG_02198	2.19e-159	-	-	-	C	-	-	-	Aldo keto reductase
MAKDMGGG_02199	8.03e-113	-	-	-	GM	-	-	-	NAD(P)H-binding
MAKDMGGG_02200	8.65e-176	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MAKDMGGG_02202	1.56e-254	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MAKDMGGG_02203	6.87e-237	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKDMGGG_02204	4.59e-36	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MAKDMGGG_02205	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MAKDMGGG_02209	1.77e-08	-	-	-	V	-	-	-	Abi-like protein
MAKDMGGG_02213	2.26e-59	-	-	-	-	-	-	-	-
MAKDMGGG_02214	7.36e-222	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
MAKDMGGG_02215	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MAKDMGGG_02216	2.6e-184	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MAKDMGGG_02217	2.15e-134	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MAKDMGGG_02218	5.37e-74	-	-	-	S	-	-	-	Pfam:DUF59
MAKDMGGG_02219	8.25e-250	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MAKDMGGG_02221	3.9e-14	-	-	-	-	-	-	-	-
MAKDMGGG_02223	9.54e-114	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MAKDMGGG_02224	2.42e-54	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MAKDMGGG_02225	8.03e-71	-	-	-	S	-	-	-	Bacteriophage holin family
MAKDMGGG_02226	4.32e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
MAKDMGGG_02229	8.52e-236	-	-	-	S	-	-	-	Peptidase family M23
MAKDMGGG_02230	7.99e-123	-	-	-	S	-	-	-	Phage tail protein
MAKDMGGG_02231	0.0	-	-	-	D	-	-	-	domain protein
MAKDMGGG_02233	7.09e-119	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
MAKDMGGG_02234	1.99e-153	-	-	-	-	-	-	-	-
MAKDMGGG_02235	9.53e-93	-	-	-	-	-	-	-	-
MAKDMGGG_02236	2.27e-122	-	-	-	-	-	-	-	-
MAKDMGGG_02237	1.08e-67	-	-	-	-	-	-	-	-
MAKDMGGG_02238	1.8e-83	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MAKDMGGG_02239	1.01e-254	gpG	-	-	-	-	-	-	-
MAKDMGGG_02240	6.76e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MAKDMGGG_02242	1.68e-225	-	-	-	S	-	-	-	Phage Mu protein F like protein
MAKDMGGG_02243	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MAKDMGGG_02244	1.5e-229	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
MAKDMGGG_02245	5.54e-86	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
MAKDMGGG_02246	4.29e-29	-	-	-	-	-	-	-	-
MAKDMGGG_02247	3.34e-24	-	-	-	-	-	-	-	-