ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
NGPDNALK_00001 1.76e-147 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
NGPDNALK_00002 6.57e-144 - - - S - - - Protein of unknown function (DUF1461)
NGPDNALK_00003 2.05e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NGPDNALK_00004 8.68e-129 yutD - - S - - - Protein of unknown function (DUF1027)
NGPDNALK_00005 9.97e-152 - - - S - - - Calcineurin-like phosphoesterase
NGPDNALK_00006 5.54e-286 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NGPDNALK_00007 9.84e-184 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
NGPDNALK_00008 8.95e-90 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
NGPDNALK_00009 4.99e-58 - - - - - - - -
NGPDNALK_00010 1.01e-100 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
NGPDNALK_00011 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
NGPDNALK_00012 1.18e-230 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
NGPDNALK_00013 2.81e-233 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
NGPDNALK_00014 7.07e-168 yebC - - K - - - Transcriptional regulatory protein
NGPDNALK_00015 1.15e-178 - - - - - - - -
NGPDNALK_00016 2.41e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
NGPDNALK_00017 1.26e-268 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NGPDNALK_00018 1.84e-75 - - - - - - - -
NGPDNALK_00019 2.43e-68 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NGPDNALK_00020 2.65e-189 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
NGPDNALK_00021 1.91e-196 - - - S - - - haloacid dehalogenase-like hydrolase
NGPDNALK_00022 3.62e-100 ykuL - - S - - - (CBS) domain
NGPDNALK_00023 3.71e-122 - - - S ko:K07095 - ko00000 Phosphoesterase
NGPDNALK_00024 3.47e-135 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NGPDNALK_00025 3.27e-187 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NGPDNALK_00026 1.18e-123 yslB - - S - - - Protein of unknown function (DUF2507)
NGPDNALK_00027 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NGPDNALK_00028 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NGPDNALK_00029 8.35e-121 cvpA - - S - - - Colicin V production protein
NGPDNALK_00030 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
NGPDNALK_00031 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NGPDNALK_00032 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
NGPDNALK_00033 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NGPDNALK_00034 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NGPDNALK_00035 1.76e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
NGPDNALK_00036 2.89e-59 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NGPDNALK_00037 2.68e-252 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NGPDNALK_00038 2.86e-244 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NGPDNALK_00039 7.5e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NGPDNALK_00040 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NGPDNALK_00041 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NGPDNALK_00042 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
NGPDNALK_00043 1.27e-250 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NGPDNALK_00044 4.8e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
NGPDNALK_00045 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NGPDNALK_00046 1.96e-194 - - - S - - - Helix-turn-helix domain
NGPDNALK_00047 1.83e-315 ymfH - - S - - - Peptidase M16
NGPDNALK_00048 4.8e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
NGPDNALK_00049 8.15e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
NGPDNALK_00050 1.02e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00051 3.13e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NGPDNALK_00052 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
NGPDNALK_00053 1.1e-194 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
NGPDNALK_00054 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
NGPDNALK_00055 2.08e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
NGPDNALK_00056 5.23e-313 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NGPDNALK_00057 1.05e-293 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
NGPDNALK_00058 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NGPDNALK_00059 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NGPDNALK_00060 6.92e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
NGPDNALK_00061 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
NGPDNALK_00062 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NGPDNALK_00063 1.37e-290 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NGPDNALK_00064 7.1e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NGPDNALK_00066 7.06e-29 - - - - - - - -
NGPDNALK_00068 1.76e-80 - - - S - - - Uncharacterised protein family (UPF0236)
NGPDNALK_00069 4.03e-98 - - - S - - - Protein of unknown function (DUF805)
NGPDNALK_00070 5.13e-60 - - - - - - - -
NGPDNALK_00071 1.81e-41 - - - - - - - -
NGPDNALK_00072 7.67e-63 - - - - - - - -
NGPDNALK_00073 3.42e-124 - - - K - - - Acetyltransferase (GNAT) domain
NGPDNALK_00074 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NGPDNALK_00075 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
NGPDNALK_00076 1.68e-233 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
NGPDNALK_00077 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
NGPDNALK_00078 3.97e-125 - - - - - - - -
NGPDNALK_00079 1.04e-33 - - - - - - - -
NGPDNALK_00080 1.57e-80 asp1 - - S - - - Asp23 family, cell envelope-related function
NGPDNALK_00081 3.93e-119 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
NGPDNALK_00083 1.11e-66 - - - - - - - -
NGPDNALK_00084 3.67e-89 - - - S - - - Belongs to the HesB IscA family
NGPDNALK_00085 5.18e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
NGPDNALK_00086 4.95e-110 - - - F - - - Hydrolase, NUDIX family
NGPDNALK_00087 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NGPDNALK_00088 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NGPDNALK_00089 1.56e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NGPDNALK_00090 3.08e-209 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
NGPDNALK_00091 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NGPDNALK_00092 2.73e-207 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
NGPDNALK_00093 1.44e-180 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NGPDNALK_00094 1.71e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NGPDNALK_00095 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
NGPDNALK_00096 1.65e-140 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
NGPDNALK_00097 1.6e-219 - - - E - - - lipolytic protein G-D-S-L family
NGPDNALK_00098 9.07e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
NGPDNALK_00099 3.53e-142 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
NGPDNALK_00100 1.22e-112 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NGPDNALK_00101 4.05e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NGPDNALK_00102 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00103 2.01e-286 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NGPDNALK_00104 6.41e-299 XK27_05225 - - S - - - Tetratricopeptide repeat protein
NGPDNALK_00105 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NGPDNALK_00106 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
NGPDNALK_00107 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
NGPDNALK_00108 7.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
NGPDNALK_00109 1.31e-65 - - - M - - - Lysin motif
NGPDNALK_00110 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
NGPDNALK_00111 2.84e-241 - - - S - - - Helix-turn-helix domain
NGPDNALK_00112 1.08e-132 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NGPDNALK_00113 3.66e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
NGPDNALK_00114 3.18e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NGPDNALK_00115 2.03e-179 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NGPDNALK_00116 4.29e-85 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NGPDNALK_00117 7.85e-210 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
NGPDNALK_00118 2.65e-215 yitL - - S ko:K00243 - ko00000 S1 domain
NGPDNALK_00119 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
NGPDNALK_00120 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
NGPDNALK_00121 1.11e-41 - - - S - - - Protein of unknown function (DUF2929)
NGPDNALK_00122 6.68e-189 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
NGPDNALK_00123 7.69e-45 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NGPDNALK_00130 4.65e-46 - - - LM - - - gp58-like protein
NGPDNALK_00131 3.61e-173 - - - M - - - Prophage endopeptidase tail
NGPDNALK_00132 1.6e-103 - - - S - - - Phage tail protein
NGPDNALK_00133 4.48e-298 - - - L - - - Phage tail tape measure protein TP901
NGPDNALK_00135 2.92e-13 - - - S - - - Phage tail assembly chaperone proteins, TAC
NGPDNALK_00136 5.43e-97 - - - S - - - Phage tail tube protein
NGPDNALK_00140 1.57e-65 - - - S - - - Phage gp6-like head-tail connector protein
NGPDNALK_00141 2.66e-255 - - - S - - - Phage capsid family
NGPDNALK_00142 4.12e-136 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
NGPDNALK_00143 4.54e-253 - - - S - - - Phage portal protein
NGPDNALK_00145 0.0 terL - - S - - - overlaps another CDS with the same product name
NGPDNALK_00146 1.05e-85 - - - L - - - Phage terminase, small subunit
NGPDNALK_00147 7.51e-93 - - - L - - - HNH nucleases
NGPDNALK_00149 2.28e-220 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
NGPDNALK_00150 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NGPDNALK_00151 1.24e-197 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
NGPDNALK_00152 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
NGPDNALK_00153 6.52e-312 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
NGPDNALK_00154 8.8e-17 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
NGPDNALK_00155 1.88e-57 pgdA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 polysaccharide deacetylase
NGPDNALK_00156 0.0 - - - G - - - Right handed beta helix region
NGPDNALK_00157 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
NGPDNALK_00158 8.96e-223 rhaS2 - - K - - - Transcriptional regulator, AraC family
NGPDNALK_00159 0.0 xylT - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NGPDNALK_00161 6.1e-276 xylR - - GK - - - ROK family
NGPDNALK_00162 1.01e-38 - - - - - - - -
NGPDNALK_00163 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
NGPDNALK_00164 1.36e-150 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NGPDNALK_00165 1.34e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NGPDNALK_00166 0.0 yclK - - T - - - Histidine kinase
NGPDNALK_00167 2.31e-173 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
NGPDNALK_00169 1.31e-108 lytE - - M - - - Lysin motif
NGPDNALK_00170 3.03e-188 - - - S - - - Cof-like hydrolase
NGPDNALK_00171 7.11e-103 - - - K - - - Transcriptional regulator
NGPDNALK_00172 0.0 oatA - - I - - - Acyltransferase
NGPDNALK_00173 1.04e-69 - - - - - - - -
NGPDNALK_00174 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NGPDNALK_00175 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NGPDNALK_00176 3.51e-161 ybbR - - S - - - YbbR-like protein
NGPDNALK_00177 4.46e-193 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NGPDNALK_00178 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
NGPDNALK_00179 1.01e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NGPDNALK_00180 3.08e-212 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NGPDNALK_00181 4.77e-216 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
NGPDNALK_00182 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NGPDNALK_00183 2.92e-98 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
NGPDNALK_00184 6.2e-114 - - - K - - - Acetyltransferase (GNAT) domain
NGPDNALK_00185 1.71e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
NGPDNALK_00186 1.97e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
NGPDNALK_00187 7.51e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NGPDNALK_00188 9.61e-137 - - - - - - - -
NGPDNALK_00189 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NGPDNALK_00190 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NGPDNALK_00191 4e-188 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
NGPDNALK_00192 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
NGPDNALK_00193 0.0 eriC - - P ko:K03281 - ko00000 chloride
NGPDNALK_00194 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NGPDNALK_00195 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NGPDNALK_00196 2.51e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NGPDNALK_00197 7.62e-290 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
NGPDNALK_00198 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NGPDNALK_00200 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NGPDNALK_00201 1.01e-308 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
NGPDNALK_00202 1.83e-21 - - - - - - - -
NGPDNALK_00204 1.37e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
NGPDNALK_00205 1.41e-239 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
NGPDNALK_00206 3.83e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
NGPDNALK_00207 0.0 steT - - E ko:K03294 - ko00000 amino acid
NGPDNALK_00208 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NGPDNALK_00209 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NGPDNALK_00210 1.03e-19 - - - - - - - -
NGPDNALK_00211 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
NGPDNALK_00212 9.52e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NGPDNALK_00213 8.24e-229 - - - - - - - -
NGPDNALK_00214 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NGPDNALK_00215 1.94e-308 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
NGPDNALK_00216 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
NGPDNALK_00217 4.78e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NGPDNALK_00218 5.52e-241 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
NGPDNALK_00219 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NGPDNALK_00220 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGPDNALK_00221 1.9e-161 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGPDNALK_00222 2.94e-46 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NGPDNALK_00223 4.3e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
NGPDNALK_00224 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NGPDNALK_00225 3.15e-278 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NGPDNALK_00226 4.26e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NGPDNALK_00227 4.28e-128 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NGPDNALK_00228 3.61e-219 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
NGPDNALK_00229 1.26e-232 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
NGPDNALK_00230 4.79e-161 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
NGPDNALK_00231 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NGPDNALK_00232 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
NGPDNALK_00233 6.76e-227 ydbI - - K - - - AI-2E family transporter
NGPDNALK_00234 2.33e-291 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
NGPDNALK_00235 3.55e-146 - - - S - - - Haloacid dehalogenase-like hydrolase
NGPDNALK_00236 2.61e-148 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NGPDNALK_00237 7.97e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NGPDNALK_00238 6.52e-219 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NGPDNALK_00239 7.12e-312 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NGPDNALK_00240 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
NGPDNALK_00241 1.97e-179 - - - K - - - LysR substrate binding domain
NGPDNALK_00242 9.94e-71 - - - S - - - branched-chain amino acid
NGPDNALK_00243 3.97e-185 - - - E - - - AzlC protein
NGPDNALK_00244 6.19e-263 hpk31 - - T - - - Histidine kinase
NGPDNALK_00245 9.76e-161 vanR - - K - - - response regulator
NGPDNALK_00246 9.9e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NGPDNALK_00247 2.18e-218 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
NGPDNALK_00248 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
NGPDNALK_00249 8.54e-305 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
NGPDNALK_00250 2.8e-299 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NGPDNALK_00251 5.64e-153 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NGPDNALK_00252 8.58e-173 - - - S - - - Protein of unknown function (DUF1129)
NGPDNALK_00253 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NGPDNALK_00254 5.8e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
NGPDNALK_00255 2.79e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NGPDNALK_00256 2.79e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
NGPDNALK_00257 5.3e-200 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
NGPDNALK_00258 9.32e-165 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
NGPDNALK_00259 2.43e-207 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
NGPDNALK_00260 2.03e-219 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
NGPDNALK_00261 3.98e-277 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
NGPDNALK_00262 2.15e-286 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NGPDNALK_00263 5.67e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00264 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NGPDNALK_00265 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NGPDNALK_00267 1.56e-144 - - - M - - - Rib/alpha-like repeat
NGPDNALK_00268 4.99e-98 - - - S ko:K07011 - ko00000 Glycosyltransferase, group 2 family protein
NGPDNALK_00269 7.27e-83 - - - S - - - Glycosyltransferase like family
NGPDNALK_00270 1.56e-95 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
NGPDNALK_00271 9.63e-38 - - - M - - - biosynthesis protein
NGPDNALK_00272 3.47e-107 - - - - - - - -
NGPDNALK_00273 8.59e-95 - - - M - - - transferase activity, transferring glycosyl groups
NGPDNALK_00274 1.62e-263 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NGPDNALK_00275 5.85e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
NGPDNALK_00276 1.65e-42 - - - - - - - -
NGPDNALK_00277 0.0 - - - G - - - Peptidase_C39 like family
NGPDNALK_00278 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
NGPDNALK_00279 3.3e-152 - - - M - - - Bacterial sugar transferase
NGPDNALK_00280 8.95e-222 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
NGPDNALK_00281 3.17e-188 cps1D - - M - - - Domain of unknown function (DUF4422)
NGPDNALK_00282 3.73e-171 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
NGPDNALK_00283 2.53e-42 - - - - - - - -
NGPDNALK_00284 4.23e-45 - - - S - - - Protein of unknown function (DUF2922)
NGPDNALK_00285 1.5e-198 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
NGPDNALK_00286 0.0 potE - - E - - - Amino Acid
NGPDNALK_00287 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NGPDNALK_00288 2.8e-280 arcT - - E - - - Aminotransferase
NGPDNALK_00289 1e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
NGPDNALK_00290 4.7e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
NGPDNALK_00291 8.59e-98 gtcA - - S - - - Teichoic acid glycosylation protein
NGPDNALK_00292 1.42e-72 - - - - - - - -
NGPDNALK_00293 1.16e-263 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NGPDNALK_00295 2.11e-293 yfmL - - L - - - DEAD DEAH box helicase
NGPDNALK_00296 2.54e-243 mocA - - S - - - Oxidoreductase
NGPDNALK_00297 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
NGPDNALK_00298 2.83e-133 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
NGPDNALK_00299 1.31e-213 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NGPDNALK_00300 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NGPDNALK_00301 6.96e-244 - - - S - - - Protein of unknown function (DUF3114)
NGPDNALK_00302 4.19e-101 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
NGPDNALK_00303 9.21e-153 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NGPDNALK_00304 1.7e-26 - - - - - - - -
NGPDNALK_00305 7.66e-96 - - - K - - - LytTr DNA-binding domain
NGPDNALK_00306 2.54e-96 - - - S - - - Protein of unknown function (DUF3021)
NGPDNALK_00307 5.94e-192 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
NGPDNALK_00308 2.78e-38 XK27_00915 - - C - - - Luciferase-like monooxygenase
NGPDNALK_00309 2.32e-153 pnb - - C - - - nitroreductase
NGPDNALK_00310 3.95e-115 - - - - - - - -
NGPDNALK_00311 2.19e-305 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
NGPDNALK_00312 1.35e-117 - - - S - - - PD-(D/E)XK nuclease family transposase
NGPDNALK_00314 7.68e-62 - - - - - - - -
NGPDNALK_00315 4.16e-198 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NGPDNALK_00316 9.64e-188 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
NGPDNALK_00317 8.81e-98 - - - K - - - LytTr DNA-binding domain
NGPDNALK_00318 4.65e-78 - - - S - - - Protein of unknown function (DUF3021)
NGPDNALK_00320 2.98e-222 - - - L - - - Plasmid pRiA4b ORF-3-like protein
NGPDNALK_00322 2.92e-107 padR - - K - - - Transcriptional regulator PadR-like family
NGPDNALK_00323 3.85e-311 - - - EGP - - - Major Facilitator
NGPDNALK_00324 4.07e-138 - - - S - - - NADPH-dependent FMN reductase
NGPDNALK_00325 4.46e-67 - - - K - - - Bacterial regulatory proteins, tetR family
NGPDNALK_00326 1.67e-58 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00327 8.38e-37 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00328 5.67e-70 - - - S - - - Belongs to the HesB IscA family
NGPDNALK_00329 3.78e-23 - - - - - - - -
NGPDNALK_00330 6.13e-27 - - - - - - - -
NGPDNALK_00331 2.53e-12 - - - K - - - LytTr DNA-binding domain
NGPDNALK_00332 1.13e-75 - - - - - - - -
NGPDNALK_00333 1.57e-94 - - - S - - - Metallo-beta-lactamase superfamily
NGPDNALK_00334 8.93e-38 - - - K - - - Psort location Cytoplasmic, score
NGPDNALK_00335 1.42e-31 - - - K - - - Psort location Cytoplasmic, score
NGPDNALK_00336 4.88e-67 yjdF3 - - S - - - Protein of unknown function (DUF2992)
NGPDNALK_00337 2.6e-134 - - - L - - - Transposase
NGPDNALK_00338 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
NGPDNALK_00339 3.57e-191 - - - E - - - Glyoxalase-like domain
NGPDNALK_00340 2.05e-187 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NGPDNALK_00341 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
NGPDNALK_00342 2.03e-200 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NGPDNALK_00343 4.85e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
NGPDNALK_00344 8.65e-276 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
NGPDNALK_00346 1.75e-65 - - - - - - - -
NGPDNALK_00347 0.0 - - - S - - - Putative peptidoglycan binding domain
NGPDNALK_00350 2.4e-249 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NGPDNALK_00351 1.65e-165 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NGPDNALK_00355 4.4e-306 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGPDNALK_00357 9.74e-98 - - - O - - - OsmC-like protein
NGPDNALK_00358 2.78e-227 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGPDNALK_00359 9.3e-272 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NGPDNALK_00360 8.68e-44 - - - - - - - -
NGPDNALK_00361 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
NGPDNALK_00362 1.78e-209 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NGPDNALK_00364 4.76e-137 - - - K - - - PFAM GCN5-related N-acetyltransferase
NGPDNALK_00365 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NGPDNALK_00366 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NGPDNALK_00367 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
NGPDNALK_00368 3e-221 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
NGPDNALK_00369 2.02e-269 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
NGPDNALK_00370 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NGPDNALK_00371 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
NGPDNALK_00372 8.72e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
NGPDNALK_00373 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
NGPDNALK_00374 3.7e-176 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NGPDNALK_00375 1.8e-215 - - - C - - - Aldo keto reductase
NGPDNALK_00376 1.86e-63 - - - S - - - Cupin 2, conserved barrel domain protein
NGPDNALK_00377 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
NGPDNALK_00378 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
NGPDNALK_00379 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NGPDNALK_00380 4.32e-232 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NGPDNALK_00381 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NGPDNALK_00382 1.47e-120 - - - - - - - -
NGPDNALK_00383 1.82e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NGPDNALK_00385 8.02e-174 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
NGPDNALK_00386 1.58e-314 - - - E - - - amino acid
NGPDNALK_00387 1.17e-22 isp - - L - - - Transposase
NGPDNALK_00388 6.7e-239 isp - - L - - - Transposase
NGPDNALK_00389 6.06e-308 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
NGPDNALK_00390 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
NGPDNALK_00391 1.09e-141 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NGPDNALK_00392 1.68e-199 - - - O - - - Uncharacterized protein family (UPF0051)
NGPDNALK_00393 1.73e-151 - - - M - - - LysM domain protein
NGPDNALK_00394 0.0 - - - EP - - - Psort location Cytoplasmic, score
NGPDNALK_00395 1.1e-131 - - - M - - - LysM domain protein
NGPDNALK_00396 2.95e-192 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NGPDNALK_00397 6.91e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NGPDNALK_00398 3.25e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NGPDNALK_00399 3.69e-196 yeaE - - S - - - Aldo keto
NGPDNALK_00400 4.63e-101 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
NGPDNALK_00401 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
NGPDNALK_00402 9.25e-103 - - - S - - - Psort location Cytoplasmic, score
NGPDNALK_00403 4.13e-110 - - - S - - - Short repeat of unknown function (DUF308)
NGPDNALK_00404 7.03e-33 - - - - - - - -
NGPDNALK_00405 1.37e-133 - - - V - - - VanZ like family
NGPDNALK_00406 5.75e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
NGPDNALK_00407 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
NGPDNALK_00408 0.0 - - - EGP - - - Major Facilitator
NGPDNALK_00409 3.41e-125 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
NGPDNALK_00410 9.47e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NGPDNALK_00411 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
NGPDNALK_00412 8.42e-55 - - - - - - - -
NGPDNALK_00413 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
NGPDNALK_00414 3.79e-191 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NGPDNALK_00415 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
NGPDNALK_00416 4.4e-112 - - - T - - - Belongs to the universal stress protein A family
NGPDNALK_00417 1.75e-221 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NGPDNALK_00418 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
NGPDNALK_00419 1.53e-146 - - - - - - - -
NGPDNALK_00420 2.41e-236 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
NGPDNALK_00421 1.63e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NGPDNALK_00422 1.52e-43 - - - - - - - -
NGPDNALK_00423 1.43e-151 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
NGPDNALK_00424 9.17e-59 - - - - - - - -
NGPDNALK_00426 2.57e-90 - - - - - - - -
NGPDNALK_00427 1.43e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NGPDNALK_00428 2.63e-120 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NGPDNALK_00429 1.17e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
NGPDNALK_00430 5.27e-281 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
NGPDNALK_00431 5.53e-132 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
NGPDNALK_00432 1.2e-263 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
NGPDNALK_00433 5.38e-60 - - - - - - - -
NGPDNALK_00434 1.22e-53 - - - - - - - -
NGPDNALK_00436 7.01e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NGPDNALK_00437 1.69e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NGPDNALK_00438 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
NGPDNALK_00439 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
NGPDNALK_00440 1.4e-63 yheA - - S - - - Belongs to the UPF0342 family
NGPDNALK_00441 1e-270 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
NGPDNALK_00442 0.0 yhaN - - L - - - AAA domain
NGPDNALK_00443 3.96e-178 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NGPDNALK_00445 2.47e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
NGPDNALK_00446 3.28e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00447 1.82e-276 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
NGPDNALK_00448 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NGPDNALK_00449 6.9e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NGPDNALK_00450 8.87e-289 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NGPDNALK_00451 2.21e-182 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
NGPDNALK_00452 2.2e-178 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NGPDNALK_00453 1e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NGPDNALK_00454 2.44e-168 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NGPDNALK_00455 2.37e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NGPDNALK_00456 7.13e-134 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
NGPDNALK_00457 6.56e-165 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
NGPDNALK_00458 1.73e-246 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
NGPDNALK_00459 8.28e-225 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NGPDNALK_00460 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NGPDNALK_00461 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NGPDNALK_00462 1.49e-176 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
NGPDNALK_00463 9.08e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NGPDNALK_00464 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
NGPDNALK_00465 1.44e-232 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
NGPDNALK_00466 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
NGPDNALK_00467 6.4e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NGPDNALK_00468 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
NGPDNALK_00469 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NGPDNALK_00470 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NGPDNALK_00471 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NGPDNALK_00472 1.25e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NGPDNALK_00473 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
NGPDNALK_00474 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGPDNALK_00475 3.81e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NGPDNALK_00476 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
NGPDNALK_00477 3.67e-176 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
NGPDNALK_00478 1.17e-121 - - - S - - - Protein of unknown function (DUF1700)
NGPDNALK_00479 9.71e-76 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
NGPDNALK_00480 2.94e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NGPDNALK_00482 3.4e-64 - - - - - - - -
NGPDNALK_00483 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NGPDNALK_00484 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NGPDNALK_00485 2e-264 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NGPDNALK_00486 1.2e-298 - - - M - - - Glycosyl transferase family group 2
NGPDNALK_00488 5.57e-290 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
NGPDNALK_00489 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NGPDNALK_00490 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NGPDNALK_00491 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
NGPDNALK_00492 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NGPDNALK_00493 2.18e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NGPDNALK_00494 2.59e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NGPDNALK_00495 8.79e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NGPDNALK_00496 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NGPDNALK_00497 2.44e-265 yacL - - S - - - domain protein
NGPDNALK_00498 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NGPDNALK_00499 1.69e-129 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
NGPDNALK_00500 1.93e-65 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
NGPDNALK_00501 7.17e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NGPDNALK_00502 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
NGPDNALK_00503 4.28e-181 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
NGPDNALK_00504 3.52e-173 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00505 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NGPDNALK_00506 4.46e-276 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
NGPDNALK_00507 1.54e-216 - - - I - - - alpha/beta hydrolase fold
NGPDNALK_00508 1.24e-171 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NGPDNALK_00509 0.0 - - - S - - - Bacterial membrane protein, YfhO
NGPDNALK_00510 6.15e-234 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
NGPDNALK_00511 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
NGPDNALK_00512 1.49e-190 - - - K - - - Helix-turn-helix XRE-family like proteins
NGPDNALK_00513 6.32e-275 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
NGPDNALK_00514 1.21e-63 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
NGPDNALK_00515 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
NGPDNALK_00516 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
NGPDNALK_00517 1.49e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
NGPDNALK_00518 1.81e-309 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NGPDNALK_00519 5.05e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
NGPDNALK_00520 8.95e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
NGPDNALK_00521 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NGPDNALK_00522 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NGPDNALK_00523 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NGPDNALK_00524 1.14e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGPDNALK_00525 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NGPDNALK_00526 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NGPDNALK_00527 3.8e-161 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
NGPDNALK_00528 1.62e-293 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
NGPDNALK_00529 1.35e-165 yibF - - S - - - overlaps another CDS with the same product name
NGPDNALK_00530 4.52e-244 yibE - - S - - - overlaps another CDS with the same product name
NGPDNALK_00531 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NGPDNALK_00532 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NGPDNALK_00533 1.49e-292 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NGPDNALK_00534 5.39e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NGPDNALK_00535 3.9e-210 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NGPDNALK_00536 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NGPDNALK_00537 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
NGPDNALK_00538 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
NGPDNALK_00539 1.63e-171 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
NGPDNALK_00540 9.76e-298 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
NGPDNALK_00541 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
NGPDNALK_00542 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NGPDNALK_00543 1.03e-303 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
NGPDNALK_00544 1.71e-241 ampC - - V - - - Beta-lactamase
NGPDNALK_00545 3.83e-74 - - - - - - - -
NGPDNALK_00546 0.0 - - - M - - - domain protein
NGPDNALK_00547 2.08e-136 - - - - - - - -
NGPDNALK_00549 1.66e-167 int2 - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_00550 1.05e-16 xre - - K - - - sequence-specific DNA binding
NGPDNALK_00551 1.3e-24 - - - S - - - Helix-turn-helix domain
NGPDNALK_00555 1.82e-57 - - - - - - - -
NGPDNALK_00556 6.37e-130 - - - S ko:K06919 - ko00000 D5 N terminal like
NGPDNALK_00563 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
NGPDNALK_00564 1.28e-75 - - - - - - - -
NGPDNALK_00566 1.82e-112 - - - - - - - -
NGPDNALK_00567 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
NGPDNALK_00568 2.2e-65 - - - S - - - Cupredoxin-like domain
NGPDNALK_00569 1.6e-82 - - - S - - - Cupredoxin-like domain
NGPDNALK_00570 9.98e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NGPDNALK_00571 7.98e-253 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
NGPDNALK_00572 4.92e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
NGPDNALK_00573 2.17e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NGPDNALK_00574 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
NGPDNALK_00575 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
NGPDNALK_00576 8.07e-76 - - - - - - - -
NGPDNALK_00577 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
NGPDNALK_00578 6.55e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NGPDNALK_00579 5.99e-74 ftsL - - D - - - Cell division protein FtsL
NGPDNALK_00580 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NGPDNALK_00581 3.83e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NGPDNALK_00582 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NGPDNALK_00583 8.06e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NGPDNALK_00584 1.73e-185 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NGPDNALK_00585 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NGPDNALK_00586 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NGPDNALK_00587 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NGPDNALK_00588 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
NGPDNALK_00589 1.84e-190 ylmH - - S - - - S4 domain protein
NGPDNALK_00590 7.47e-109 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
NGPDNALK_00591 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NGPDNALK_00592 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NGPDNALK_00593 1.01e-128 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
NGPDNALK_00594 1.54e-33 - - - - - - - -
NGPDNALK_00595 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NGPDNALK_00596 1.1e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
NGPDNALK_00597 2.27e-75 XK27_04120 - - S - - - Putative amino acid metabolism
NGPDNALK_00598 2.15e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NGPDNALK_00599 4.02e-159 pgm6 - - G - - - phosphoglycerate mutase
NGPDNALK_00600 3.82e-157 - - - S - - - repeat protein
NGPDNALK_00601 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NGPDNALK_00602 1.48e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NGPDNALK_00603 3.08e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NGPDNALK_00604 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
NGPDNALK_00605 9.53e-317 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NGPDNALK_00606 2.66e-111 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NGPDNALK_00607 6.66e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NGPDNALK_00608 1.96e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NGPDNALK_00609 4.65e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NGPDNALK_00610 3.27e-276 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NGPDNALK_00611 1.82e-254 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NGPDNALK_00612 2.07e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
NGPDNALK_00613 1.25e-74 - - - - - - - -
NGPDNALK_00616 1.13e-295 - - - L ko:K07484 - ko00000 Transposase IS66 family
NGPDNALK_00617 5.21e-86 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NGPDNALK_00619 2.18e-121 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
NGPDNALK_00620 2.78e-98 - - - S - - - Bacteriophage holin family
NGPDNALK_00623 1.25e-249 - - - S - - - peptidoglycan catabolic process
NGPDNALK_00625 1.61e-229 - - - S - - - peptidoglycan catabolic process
NGPDNALK_00627 2.04e-59 - - - S - - - Pfam:Phage_TAC_12
NGPDNALK_00628 3.82e-110 - - - S - - - Phage major tail protein 2
NGPDNALK_00629 6.25e-57 - - - - - - - -
NGPDNALK_00630 1.27e-57 - - - S - - - exonuclease activity
NGPDNALK_00632 3.3e-61 - - - S - - - Phage gp6-like head-tail connector protein
NGPDNALK_00633 2.35e-148 - - - - - - - -
NGPDNALK_00634 1.55e-83 - - - S - - - aminoacyl-tRNA ligase activity
NGPDNALK_00636 2.6e-177 - - - S - - - Phage Mu protein F like protein
NGPDNALK_00637 2.58e-260 - - - S - - - Phage portal protein, SPP1 Gp6-like
NGPDNALK_00638 4.71e-301 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
NGPDNALK_00639 8.89e-86 - - - L ko:K07474 - ko00000 Terminase small subunit
NGPDNALK_00640 2.81e-18 - - - S - - - Super-infection exclusion protein B
NGPDNALK_00641 1.2e-105 - - - S - - - Phage transcriptional regulator, ArpU family
NGPDNALK_00644 1.18e-50 - - - - - - - -
NGPDNALK_00647 3.45e-28 - - - - - - - -
NGPDNALK_00649 6.11e-77 - - - S - - - VRR_NUC
NGPDNALK_00651 9.04e-294 - - - S ko:K06919 - ko00000 Virulence-associated protein E
NGPDNALK_00652 5.66e-186 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NGPDNALK_00653 2.84e-120 - - - - - - - -
NGPDNALK_00654 2.13e-181 - - - L - - - AAA domain
NGPDNALK_00655 0.0 - - - L - - - Helicase C-terminal domain protein
NGPDNALK_00656 2.12e-107 - - - S - - - Siphovirus Gp157
NGPDNALK_00659 6.06e-37 - - - - - - - -
NGPDNALK_00662 4.29e-51 - - - - - - - -
NGPDNALK_00664 8.81e-19 - - - K - - - Peptidase S24-like
NGPDNALK_00665 1.75e-21 - - - E - - - Zn peptidase
NGPDNALK_00666 3.24e-35 - - - S - - - Bacterial PH domain
NGPDNALK_00667 1.72e-25 - - - - - - - -
NGPDNALK_00668 8.95e-273 int2 - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_00678 2.38e-85 - - - L - - - Transposase
NGPDNALK_00679 1.74e-190 - - - L - - - Transposase
NGPDNALK_00680 4.7e-282 - - - L - - - transposase IS116 IS110 IS902 family protein
NGPDNALK_00682 5.58e-70 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NGPDNALK_00683 1.21e-64 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NGPDNALK_00684 1.77e-198 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
NGPDNALK_00685 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NGPDNALK_00686 5.25e-215 cpsY - - K - - - Transcriptional regulator, LysR family
NGPDNALK_00687 8.25e-77 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NGPDNALK_00688 1.21e-18 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NGPDNALK_00689 1.52e-24 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NGPDNALK_00690 1.16e-112 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NGPDNALK_00691 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
NGPDNALK_00693 4.06e-287 - - - S ko:K07133 - ko00000 cog cog1373
NGPDNALK_00694 9.72e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
NGPDNALK_00695 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NGPDNALK_00696 7.51e-204 - - - EG - - - EamA-like transporter family
NGPDNALK_00697 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NGPDNALK_00698 4.66e-312 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
NGPDNALK_00699 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
NGPDNALK_00700 1.14e-148 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
NGPDNALK_00701 4.71e-162 pgm3 - - G - - - phosphoglycerate mutase
NGPDNALK_00702 5.29e-300 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NGPDNALK_00703 1.34e-47 - - - S - - - Transglycosylase associated protein
NGPDNALK_00704 3.27e-13 - - - S - - - CsbD-like
NGPDNALK_00705 7.72e-231 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGPDNALK_00706 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
NGPDNALK_00707 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
NGPDNALK_00708 7.13e-52 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
NGPDNALK_00709 3.82e-192 - - - - - - - -
NGPDNALK_00710 4.56e-34 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
NGPDNALK_00711 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
NGPDNALK_00712 9.66e-133 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
NGPDNALK_00713 1.78e-97 - - - F - - - Nudix hydrolase
NGPDNALK_00714 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
NGPDNALK_00715 1.3e-300 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
NGPDNALK_00716 4.14e-295 - - - - - - - -
NGPDNALK_00717 2.08e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NGPDNALK_00718 1.04e-181 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NGPDNALK_00719 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NGPDNALK_00720 5.08e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NGPDNALK_00721 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NGPDNALK_00722 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
NGPDNALK_00723 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
NGPDNALK_00724 3.42e-111 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
NGPDNALK_00725 5.28e-316 yagE - - E - - - amino acid
NGPDNALK_00726 1.06e-148 - - - S - - - HAD hydrolase, family IA, variant
NGPDNALK_00727 2.41e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
NGPDNALK_00728 1.1e-232 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
NGPDNALK_00729 4.29e-175 - - - IQ - - - KR domain
NGPDNALK_00730 1.03e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
NGPDNALK_00731 5.18e-128 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
NGPDNALK_00732 2.71e-316 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00733 3.54e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NGPDNALK_00734 6.5e-71 - - - - - - - -
NGPDNALK_00735 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
NGPDNALK_00736 1.28e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
NGPDNALK_00737 5.96e-240 ybcH - - D ko:K06889 - ko00000 Alpha beta
NGPDNALK_00738 1.3e-95 - - - K - - - Transcriptional regulator
NGPDNALK_00739 1.65e-205 - - - - - - - -
NGPDNALK_00740 5.48e-20 - - - C - - - Zinc-binding dehydrogenase
NGPDNALK_00741 8.78e-95 - - - C - - - Zinc-binding dehydrogenase
NGPDNALK_00742 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
NGPDNALK_00743 1.37e-270 - - - EGP - - - Major Facilitator
NGPDNALK_00744 1.59e-175 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
NGPDNALK_00745 7e-153 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
NGPDNALK_00746 3.18e-11 - - - - - - - -
NGPDNALK_00747 1.78e-83 - - - - - - - -
NGPDNALK_00748 8.24e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
NGPDNALK_00749 7.46e-106 uspA3 - - T - - - universal stress protein
NGPDNALK_00750 0.0 fusA1 - - J - - - elongation factor G
NGPDNALK_00751 3.76e-214 - - - GK - - - ROK family
NGPDNALK_00752 3.4e-311 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NGPDNALK_00753 1.19e-175 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
NGPDNALK_00754 7.11e-309 - - - E - - - amino acid
NGPDNALK_00755 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
NGPDNALK_00756 1.05e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
NGPDNALK_00757 2.85e-114 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NGPDNALK_00758 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NGPDNALK_00759 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
NGPDNALK_00760 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00761 3.33e-241 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGPDNALK_00762 1.7e-173 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
NGPDNALK_00763 2.34e-187 - - - - - - - -
NGPDNALK_00764 2.34e-203 - - - G - - - Xylose isomerase domain protein TIM barrel
NGPDNALK_00765 3.95e-238 XK27_12525 - - S - - - AI-2E family transporter
NGPDNALK_00766 1.56e-172 XK27_07210 - - S - - - B3 4 domain
NGPDNALK_00767 1.93e-101 yybA - - K - - - Transcriptional regulator
NGPDNALK_00768 5.25e-118 - - - K - - - Domain of unknown function (DUF1836)
NGPDNALK_00769 1.63e-116 - - - GM - - - epimerase
NGPDNALK_00770 4.86e-199 - - - V - - - (ABC) transporter
NGPDNALK_00771 8.65e-310 yhdP - - S - - - Transporter associated domain
NGPDNALK_00772 4e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NGPDNALK_00773 4.3e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
NGPDNALK_00774 5.09e-244 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
NGPDNALK_00775 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NGPDNALK_00776 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NGPDNALK_00777 4.85e-52 - - - - - - - -
NGPDNALK_00778 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NGPDNALK_00779 2.32e-104 usp5 - - T - - - universal stress protein
NGPDNALK_00780 9.78e-107 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
NGPDNALK_00781 1.24e-295 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NGPDNALK_00782 2.23e-135 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
NGPDNALK_00783 6.6e-230 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NGPDNALK_00784 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
NGPDNALK_00785 1.79e-288 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NGPDNALK_00786 5.2e-225 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
NGPDNALK_00787 7.76e-187 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
NGPDNALK_00788 3.75e-119 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
NGPDNALK_00789 1.21e-48 - - - - - - - -
NGPDNALK_00790 7.19e-68 - - - - - - - -
NGPDNALK_00791 1.69e-256 - - - - - - - -
NGPDNALK_00792 5.53e-106 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NGPDNALK_00793 1.38e-175 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NGPDNALK_00794 4.18e-201 yvgN - - S - - - Aldo keto reductase
NGPDNALK_00795 1.06e-161 XK27_10500 - - K - - - response regulator
NGPDNALK_00796 1.19e-230 kinG - - T - - - Histidine kinase-like ATPases
NGPDNALK_00797 2.48e-174 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00798 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
NGPDNALK_00799 4.33e-196 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
NGPDNALK_00800 5.95e-210 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NGPDNALK_00801 1.38e-67 - - - K - - - helix_turn_helix, mercury resistance
NGPDNALK_00802 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NGPDNALK_00803 1.3e-247 - - - EGP - - - Major Facilitator
NGPDNALK_00804 3.48e-112 ymdB - - S - - - Macro domain protein
NGPDNALK_00805 2.49e-141 - - - K - - - Helix-turn-helix domain
NGPDNALK_00806 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
NGPDNALK_00807 1.21e-63 - - - - - - - -
NGPDNALK_00808 3.4e-294 - - - S - - - Putative metallopeptidase domain
NGPDNALK_00809 7.71e-257 - - - S - - - associated with various cellular activities
NGPDNALK_00810 8.15e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
NGPDNALK_00811 5.51e-86 yeaO - - S - - - Protein of unknown function, DUF488
NGPDNALK_00813 1.08e-147 yrkL - - S - - - Flavodoxin-like fold
NGPDNALK_00814 3.32e-72 - - - - - - - -
NGPDNALK_00816 1.08e-157 - - - S - - - PD-(D/E)XK nuclease family transposase
NGPDNALK_00817 2.04e-65 - - - - - - - -
NGPDNALK_00818 1.62e-256 yngD - - S ko:K07097 - ko00000 DHHA1 domain
NGPDNALK_00819 7.39e-293 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
NGPDNALK_00820 2.51e-314 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
NGPDNALK_00821 4.21e-137 - - - NU - - - mannosyl-glycoprotein
NGPDNALK_00822 1.23e-178 - - - S - - - Putative ABC-transporter type IV
NGPDNALK_00823 0.0 - - - S - - - ABC transporter, ATP-binding protein
NGPDNALK_00824 1.11e-117 - - - K - - - Helix-turn-helix domain
NGPDNALK_00825 8.21e-65 - - - - - - - -
NGPDNALK_00827 2.21e-27 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
NGPDNALK_00828 6.21e-51 - - - M - - - Sortase family
NGPDNALK_00829 6.85e-95 - - - K - - - Transcriptional regulator, TetR family
NGPDNALK_00830 2.3e-165 - - - M - - - PFAM NLP P60 protein
NGPDNALK_00831 7.76e-234 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NGPDNALK_00832 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
NGPDNALK_00833 3.96e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00834 7.02e-122 - - - P - - - Cadmium resistance transporter
NGPDNALK_00835 2.29e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NGPDNALK_00836 2.54e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NGPDNALK_00837 1.08e-168 yceF - - P ko:K05794 - ko00000 membrane
NGPDNALK_00838 4.59e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
NGPDNALK_00839 8.21e-216 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NGPDNALK_00840 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NGPDNALK_00841 4.79e-307 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
NGPDNALK_00842 3.99e-315 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NGPDNALK_00843 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
NGPDNALK_00844 9.5e-162 pgm3 - - G - - - phosphoglycerate mutase family
NGPDNALK_00845 1.45e-55 - - - - - - - -
NGPDNALK_00846 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NGPDNALK_00847 3.46e-265 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
NGPDNALK_00848 1.78e-26 - - - - - - - -
NGPDNALK_00851 9.75e-101 - - - K - - - Peptidase S24-like
NGPDNALK_00852 3.17e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
NGPDNALK_00854 3.14e-17 - - - S - - - Domain of unknown function (DUF4145)
NGPDNALK_00855 1.46e-20 - - - K - - - Cro/C1-type HTH DNA-binding domain
NGPDNALK_00856 1.62e-26 - - - - - - - -
NGPDNALK_00859 2.41e-174 - - - L - - - DnaD domain protein
NGPDNALK_00861 8.03e-92 - - - - - - - -
NGPDNALK_00862 2.2e-171 - - - - - - - -
NGPDNALK_00867 2.22e-108 - - - S - - - Phage transcriptional regulator, ArpU family
NGPDNALK_00868 1.15e-126 - - - K - - - acetyltransferase
NGPDNALK_00869 4.53e-47 - - - S - - - ASCH
NGPDNALK_00871 5.71e-194 - - - L - - - HNH nucleases
NGPDNALK_00872 8.04e-101 - - - L - - - Phage terminase, small subunit
NGPDNALK_00873 0.0 terL - - S - - - overlaps another CDS with the same product name
NGPDNALK_00876 1.03e-303 - - - S - - - Phage portal protein
NGPDNALK_00877 5.63e-145 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NGPDNALK_00878 1.5e-196 - - - S - - - Phage capsid family
NGPDNALK_00879 1.07e-85 - - - S - - - Phage gp6-like head-tail connector protein
NGPDNALK_00880 6.4e-54 - - - S - - - Phage head-tail joining protein
NGPDNALK_00881 1.85e-82 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
NGPDNALK_00882 5.69e-100 - - - - - - - -
NGPDNALK_00883 3.57e-144 - - - - - - - -
NGPDNALK_00885 8.23e-28 - - - - - - - -
NGPDNALK_00886 0.0 - - - L - - - Phage tail tape measure protein TP901
NGPDNALK_00887 1.7e-151 - - - S - - - Phage tail protein
NGPDNALK_00888 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
NGPDNALK_00890 2.22e-128 - - - M - - - CotH kinase protein
NGPDNALK_00893 2.88e-47 - - - S - - - Bacteriophage holin family
NGPDNALK_00894 6.66e-74 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NGPDNALK_00895 4.27e-252 - - - M - - - hydrolase, family 25
NGPDNALK_00897 6.82e-128 - - - K - - - DNA-binding helix-turn-helix protein
NGPDNALK_00898 1.78e-208 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
NGPDNALK_00899 9.43e-73 - - - - - - - -
NGPDNALK_00900 6.51e-270 yttB - - EGP - - - Major Facilitator
NGPDNALK_00901 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
NGPDNALK_00902 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NGPDNALK_00903 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
NGPDNALK_00904 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NGPDNALK_00905 2.82e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NGPDNALK_00906 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
NGPDNALK_00907 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NGPDNALK_00908 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NGPDNALK_00909 1.7e-261 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NGPDNALK_00910 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
NGPDNALK_00911 8.13e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NGPDNALK_00912 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NGPDNALK_00913 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
NGPDNALK_00914 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NGPDNALK_00915 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NGPDNALK_00916 9.93e-167 jag - - S ko:K06346 - ko00000 R3H domain protein
NGPDNALK_00917 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NGPDNALK_00918 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NGPDNALK_00919 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
NGPDNALK_00920 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NGPDNALK_00921 1.04e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
NGPDNALK_00922 2.44e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
NGPDNALK_00923 9.23e-116 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
NGPDNALK_00924 9.53e-206 - - - S - - - reductase
NGPDNALK_00926 1.57e-10 - - - S - - - Protein of unknown function (DUF1211)
NGPDNALK_00928 8.44e-70 - - - K - - - LysR substrate binding domain
NGPDNALK_00929 1.26e-24 - - - S - - - amidohydrolase
NGPDNALK_00930 1.21e-296 - - - S - - - amidohydrolase
NGPDNALK_00931 9.31e-49 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
NGPDNALK_00932 4.25e-110 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00933 1.79e-212 - - - G - - - Phosphotransferase enzyme family
NGPDNALK_00934 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NGPDNALK_00935 3e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_00936 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NGPDNALK_00937 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
NGPDNALK_00938 2.34e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
NGPDNALK_00939 8.77e-237 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NGPDNALK_00940 3.59e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
NGPDNALK_00941 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
NGPDNALK_00942 2.1e-95 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
NGPDNALK_00943 2e-216 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NGPDNALK_00944 6.13e-233 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
NGPDNALK_00945 7.1e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NGPDNALK_00946 7.06e-79 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
NGPDNALK_00947 2.1e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NGPDNALK_00948 4.65e-184 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
NGPDNALK_00949 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
NGPDNALK_00950 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
NGPDNALK_00951 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NGPDNALK_00952 5.12e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NGPDNALK_00953 5.91e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NGPDNALK_00954 1.96e-163 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
NGPDNALK_00955 1.4e-196 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NGPDNALK_00956 9.52e-303 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
NGPDNALK_00957 6.69e-84 - - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_00958 8.96e-10 - - - J - - - Phage integrase family
NGPDNALK_00960 1.16e-92 - - - - - - - -
NGPDNALK_00961 2.74e-26 - - - - - - - -
NGPDNALK_00963 2.17e-34 - - - K - - - Helix-turn-helix XRE-family like proteins
NGPDNALK_00964 1.92e-25 - - - - - - - -
NGPDNALK_00970 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
NGPDNALK_00971 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NGPDNALK_00972 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NGPDNALK_00973 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NGPDNALK_00974 2.98e-104 - - - S ko:K19055 - ko00000,ko01000,ko03016 YbaK proline--tRNA ligase associated domain protein
NGPDNALK_00975 0.0 - - - E - - - amino acid
NGPDNALK_00976 0.0 ydaO - - E - - - amino acid
NGPDNALK_00977 1.78e-51 - - - - - - - -
NGPDNALK_00978 9.89e-86 - - - K - - - Transcriptional regulator
NGPDNALK_00979 1.26e-07 - - - EGP - - - Major Facilitator
NGPDNALK_00980 1.33e-110 - - - EGP - - - Major Facilitator
NGPDNALK_00981 3.26e-95 - - - EGP - - - Major Facilitator
NGPDNALK_00982 1.63e-145 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
NGPDNALK_00983 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
NGPDNALK_00984 2.41e-164 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
NGPDNALK_00985 5e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NGPDNALK_00986 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NGPDNALK_00987 1.11e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NGPDNALK_00988 2.47e-65 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
NGPDNALK_00989 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
NGPDNALK_00990 2.29e-225 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NGPDNALK_00991 3.18e-198 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NGPDNALK_00992 3.83e-233 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
NGPDNALK_00993 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
NGPDNALK_00994 2.5e-175 lutC - - S ko:K00782 - ko00000 LUD domain
NGPDNALK_00995 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
NGPDNALK_00996 1.2e-200 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
NGPDNALK_00997 3.37e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NGPDNALK_00998 3.23e-269 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NGPDNALK_00999 2.53e-209 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
NGPDNALK_01000 1.36e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
NGPDNALK_01001 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NGPDNALK_01002 0.0 - - - M - - - family 8
NGPDNALK_01003 6.92e-128 - - - S - - - glycosyl transferase family 2
NGPDNALK_01004 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NGPDNALK_01005 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
NGPDNALK_01006 6.57e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
NGPDNALK_01007 1.6e-191 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NGPDNALK_01008 2.5e-154 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
NGPDNALK_01010 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NGPDNALK_01011 2.76e-212 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
NGPDNALK_01012 1.81e-291 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
NGPDNALK_01013 2.14e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NGPDNALK_01014 1.15e-282 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NGPDNALK_01015 7.79e-185 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
NGPDNALK_01016 4.67e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
NGPDNALK_01017 3.5e-223 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NGPDNALK_01018 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
NGPDNALK_01019 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
NGPDNALK_01020 1.16e-239 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
NGPDNALK_01021 3.81e-110 - - - - - - - -
NGPDNALK_01022 2.17e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
NGPDNALK_01023 2.58e-71 - - - S - - - Mazg nucleotide pyrophosphohydrolase
NGPDNALK_01024 3.94e-45 - - - - - - - -
NGPDNALK_01025 2.19e-100 - - - - - - - -
NGPDNALK_01026 1.62e-229 - - - - - - - -
NGPDNALK_01027 1.45e-233 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
NGPDNALK_01028 1.96e-179 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
NGPDNALK_01029 2.63e-168 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NGPDNALK_01030 2.96e-100 - - - S - - - Flavodoxin
NGPDNALK_01031 2.29e-84 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
NGPDNALK_01032 9.9e-49 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
NGPDNALK_01033 1.51e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
NGPDNALK_01034 2.29e-114 - - - H - - - geranyltranstransferase activity
NGPDNALK_01035 3.94e-37 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
NGPDNALK_01036 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NGPDNALK_01037 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
NGPDNALK_01038 5.76e-128 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
NGPDNALK_01039 4.68e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
NGPDNALK_01040 1.33e-196 - - - EG - - - EamA-like transporter family
NGPDNALK_01041 1.63e-152 - - - L - - - Integrase
NGPDNALK_01042 1.03e-203 rssA - - S - - - Phospholipase, patatin family
NGPDNALK_01043 1.16e-29 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
NGPDNALK_01044 5.29e-109 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
NGPDNALK_01045 1.56e-254 xerS - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_01047 2.41e-92 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NGPDNALK_01048 9.21e-99 - - - K - - - Transcriptional regulator, MarR family
NGPDNALK_01049 1.07e-88 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NGPDNALK_01050 1.48e-64 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NGPDNALK_01051 1.08e-13 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGPDNALK_01052 9.96e-19 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGPDNALK_01053 6.13e-191 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
NGPDNALK_01054 9.08e-153 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
NGPDNALK_01055 3.88e-42 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NGPDNALK_01056 9.22e-73 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NGPDNALK_01057 1.19e-135 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
NGPDNALK_01058 1.42e-103 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NGPDNALK_01059 7.04e-173 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
NGPDNALK_01060 2.11e-19 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NGPDNALK_01061 3.51e-132 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
NGPDNALK_01070 4.29e-29 - - - - - - - -
NGPDNALK_01071 5.54e-86 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
NGPDNALK_01072 1.5e-229 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
NGPDNALK_01073 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
NGPDNALK_01074 1.68e-225 - - - S - - - Phage Mu protein F like protein
NGPDNALK_01076 6.76e-137 - - - S - - - Domain of unknown function (DUF4355)
NGPDNALK_01077 1.01e-254 gpG - - - - - - -
NGPDNALK_01078 1.8e-83 - - - S - - - Phage gp6-like head-tail connector protein
NGPDNALK_01079 1.08e-67 - - - - - - - -
NGPDNALK_01080 1.37e-123 - - - - - - - -
NGPDNALK_01081 9.53e-93 - - - - - - - -
NGPDNALK_01082 1.99e-153 - - - - - - - -
NGPDNALK_01083 7.09e-119 - - - S - - - Phage tail assembly chaperone protein, TAC
NGPDNALK_01084 0.0 - - - D - - - domain protein
NGPDNALK_01085 7.99e-123 - - - S - - - Phage tail protein
NGPDNALK_01086 8.52e-236 - - - S - - - Peptidase family M23
NGPDNALK_01089 4.32e-74 - - - S - - - Domain of unknown function (DUF2479)
NGPDNALK_01090 8.03e-71 - - - S - - - Bacteriophage holin family
NGPDNALK_01091 2.42e-54 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
NGPDNALK_01092 9.54e-114 - - - M - - - Glycosyl hydrolases family 25
NGPDNALK_01094 3.9e-14 - - - - - - - -
NGPDNALK_01096 4.03e-173 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NGPDNALK_01097 1.75e-67 - - - - - - - -
NGPDNALK_01098 0.0 - - - S - - - SEC-C Motif Domain Protein
NGPDNALK_01099 7.33e-143 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
NGPDNALK_01100 6.33e-140 - - - K - - - Transcriptional regulator, TetR family
NGPDNALK_01101 4.06e-93 - - - - - - - -
NGPDNALK_01102 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NGPDNALK_01103 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
NGPDNALK_01104 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NGPDNALK_01105 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
NGPDNALK_01106 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NGPDNALK_01107 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
NGPDNALK_01108 3.42e-235 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
NGPDNALK_01109 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NGPDNALK_01111 2.19e-131 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NGPDNALK_01112 2.11e-274 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
NGPDNALK_01113 1.28e-225 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NGPDNALK_01114 1.97e-53 - - - S - - - Protein of unknown function (DUF1797)
NGPDNALK_01115 6.57e-229 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NGPDNALK_01116 7.98e-253 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NGPDNALK_01117 3.48e-288 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
NGPDNALK_01118 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NGPDNALK_01119 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
NGPDNALK_01120 5.62e-37 - - - - - - - -
NGPDNALK_01121 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
NGPDNALK_01122 1.75e-127 - - - S - - - Pfam:DUF3816
NGPDNALK_01123 9.48e-183 - - - G - - - MucBP domain
NGPDNALK_01124 5.54e-146 - - - - - - - -
NGPDNALK_01125 1.3e-201 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_01126 7.18e-86 - - - K - - - Transcriptional regulator, GntR family
NGPDNALK_01127 0.0 - - - S - - - Peptidase, M23
NGPDNALK_01128 2.76e-90 - - - S - - - Peptidase, M23
NGPDNALK_01129 0.0 - - - M - - - NlpC/P60 family
NGPDNALK_01130 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NGPDNALK_01131 2.18e-297 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NGPDNALK_01132 2.63e-232 yueF - - S - - - AI-2E family transporter
NGPDNALK_01133 0.0 - - - G - - - Peptidase_C39 like family
NGPDNALK_01134 1.28e-195 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NGPDNALK_01135 1.03e-72 - - - - - - - -
NGPDNALK_01136 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NGPDNALK_01138 1.79e-42 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NGPDNALK_01139 2.16e-28 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NGPDNALK_01140 1.21e-132 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
NGPDNALK_01141 3.01e-273 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
NGPDNALK_01142 9.89e-315 - - - E ko:K03294 - ko00000 amino acid
NGPDNALK_01143 6.64e-233 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NGPDNALK_01144 1.17e-270 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
NGPDNALK_01145 1.51e-52 - - - S - - - Cytochrome B5
NGPDNALK_01146 8.47e-08 - - - S - - - Cytochrome B5
NGPDNALK_01147 7.72e-51 - - - S - - - Cytochrome B5
NGPDNALK_01148 9.65e-95 - - - S ko:K02348 - ko00000 Gnat family
NGPDNALK_01149 2e-14 - - - GM - - - NmrA-like family
NGPDNALK_01150 4.55e-68 ydeP - - K - - - Transcriptional regulator, HxlR family
NGPDNALK_01151 1.3e-137 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
NGPDNALK_01152 3.67e-74 - - - K - - - Transcriptional regulator, HxlR family
NGPDNALK_01153 1.16e-300 - - - - - - - -
NGPDNALK_01154 3.09e-268 - - - EGP - - - Major Facilitator Superfamily
NGPDNALK_01155 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
NGPDNALK_01156 1.97e-143 - - - GM - - - NAD dependent epimerase dehydratase family protein
NGPDNALK_01157 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
NGPDNALK_01158 1.79e-119 - - - S - - - ECF transporter, substrate-specific component
NGPDNALK_01159 3.51e-253 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
NGPDNALK_01160 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
NGPDNALK_01161 4.53e-66 isp - - L - - - Transposase
NGPDNALK_01162 1.56e-96 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
NGPDNALK_01163 4.43e-43 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
NGPDNALK_01164 1.22e-144 ung2 - - L - - - Uracil-DNA glycosylase
NGPDNALK_01165 3.96e-145 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
NGPDNALK_01166 1.09e-122 dpsB - - P - - - Belongs to the Dps family
NGPDNALK_01167 2.25e-45 - - - C - - - Heavy-metal-associated domain
NGPDNALK_01168 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
NGPDNALK_01169 7.15e-133 - - - - - - - -
NGPDNALK_01170 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NGPDNALK_01171 1.64e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
NGPDNALK_01172 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGPDNALK_01173 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NGPDNALK_01174 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NGPDNALK_01175 1.11e-260 camS - - S - - - sex pheromone
NGPDNALK_01176 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NGPDNALK_01177 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
NGPDNALK_01178 8.91e-270 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NGPDNALK_01179 2.36e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NGPDNALK_01180 3.07e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
NGPDNALK_01181 1.82e-179 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
NGPDNALK_01182 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
NGPDNALK_01183 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NGPDNALK_01184 1.75e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NGPDNALK_01185 8.27e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGPDNALK_01186 4.31e-198 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGPDNALK_01187 2.47e-186 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NGPDNALK_01188 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
NGPDNALK_01189 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGPDNALK_01190 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NGPDNALK_01191 5.37e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NGPDNALK_01192 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
NGPDNALK_01193 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NGPDNALK_01194 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NGPDNALK_01195 1.66e-305 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NGPDNALK_01196 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
NGPDNALK_01197 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
NGPDNALK_01198 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NGPDNALK_01199 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NGPDNALK_01200 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NGPDNALK_01201 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NGPDNALK_01202 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NGPDNALK_01203 5.22e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NGPDNALK_01204 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NGPDNALK_01205 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NGPDNALK_01206 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
NGPDNALK_01207 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NGPDNALK_01208 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NGPDNALK_01209 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NGPDNALK_01210 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NGPDNALK_01211 1.64e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NGPDNALK_01212 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NGPDNALK_01213 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
NGPDNALK_01214 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NGPDNALK_01215 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
NGPDNALK_01216 1.07e-40 - - - L - - - Transposase
NGPDNALK_01217 5.13e-209 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NGPDNALK_01218 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NGPDNALK_01219 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NGPDNALK_01220 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NGPDNALK_01221 2.44e-119 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
NGPDNALK_01222 2.13e-259 - - - - - - - -
NGPDNALK_01223 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGPDNALK_01224 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NGPDNALK_01225 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
NGPDNALK_01226 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NGPDNALK_01227 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
NGPDNALK_01228 4.25e-248 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NGPDNALK_01229 2.3e-229 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
NGPDNALK_01235 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
NGPDNALK_01236 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
NGPDNALK_01238 2.79e-153 - - - I - - - phosphatase
NGPDNALK_01239 3.68e-107 - - - S - - - Threonine/Serine exporter, ThrE
NGPDNALK_01240 5.6e-171 - - - S - - - Putative threonine/serine exporter
NGPDNALK_01241 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
NGPDNALK_01242 1.15e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
NGPDNALK_01243 4.92e-213 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
NGPDNALK_01244 7.33e-152 - - - S - - - membrane
NGPDNALK_01245 2.34e-142 - - - S - - - VIT family
NGPDNALK_01246 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
NGPDNALK_01247 1.97e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_01248 5.46e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NGPDNALK_01249 3.03e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NGPDNALK_01250 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NGPDNALK_01251 1.44e-275 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
NGPDNALK_01252 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NGPDNALK_01253 1.11e-72 - - - - - - - -
NGPDNALK_01254 3.21e-99 - - - K - - - MerR HTH family regulatory protein
NGPDNALK_01255 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
NGPDNALK_01256 1.03e-157 - - - S - - - Domain of unknown function (DUF4811)
NGPDNALK_01257 6.48e-210 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NGPDNALK_01259 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NGPDNALK_01260 7.94e-134 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
NGPDNALK_01261 6e-29 - - - I - - - Alpha beta
NGPDNALK_01262 2.33e-195 - - - I - - - Alpha beta
NGPDNALK_01263 0.0 qacA - - EGP - - - Major Facilitator
NGPDNALK_01264 5.46e-152 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
NGPDNALK_01265 0.0 - - - S - - - Putative threonine/serine exporter
NGPDNALK_01266 4.66e-201 - - - K - - - LysR family
NGPDNALK_01267 3.59e-143 - - - I - - - Alpha/beta hydrolase family
NGPDNALK_01268 4.45e-193 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NGPDNALK_01269 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
NGPDNALK_01270 1.56e-202 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
NGPDNALK_01271 4.97e-54 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
NGPDNALK_01272 1.14e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NGPDNALK_01273 9.44e-223 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
NGPDNALK_01274 8.74e-158 citR - - K - - - sugar-binding domain protein
NGPDNALK_01275 6.12e-216 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
NGPDNALK_01276 6.01e-166 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NGPDNALK_01277 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
NGPDNALK_01278 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NGPDNALK_01279 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
NGPDNALK_01280 5.46e-207 mleR - - K - - - LysR family
NGPDNALK_01281 4.07e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NGPDNALK_01282 6.4e-262 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
NGPDNALK_01283 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
NGPDNALK_01284 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
NGPDNALK_01287 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
NGPDNALK_01288 1.75e-29 - - - - - - - -
NGPDNALK_01289 3.09e-211 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NGPDNALK_01290 5.93e-149 - - - S - - - Protein of unknown function (DUF421)
NGPDNALK_01291 6.49e-94 - - - S - - - Protein of unknown function (DUF3290)
NGPDNALK_01292 4.12e-56 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
NGPDNALK_01293 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NGPDNALK_01294 4.69e-200 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
NGPDNALK_01295 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
NGPDNALK_01297 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NGPDNALK_01298 8.97e-292 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
NGPDNALK_01299 6.83e-157 - - - S - - - SNARE associated Golgi protein
NGPDNALK_01300 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
NGPDNALK_01301 5.16e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NGPDNALK_01302 2.83e-73 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NGPDNALK_01303 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NGPDNALK_01304 7.61e-181 - - - S - - - DUF218 domain
NGPDNALK_01305 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
NGPDNALK_01306 2.75e-316 yhdP - - S - - - Transporter associated domain
NGPDNALK_01307 2.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
NGPDNALK_01308 5.59e-307 - - - U - - - Belongs to the major facilitator superfamily
NGPDNALK_01309 6.68e-98 - - - S - - - UPF0756 membrane protein
NGPDNALK_01310 1.06e-104 - - - S - - - Cupin domain
NGPDNALK_01311 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NGPDNALK_01312 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
NGPDNALK_01313 2.63e-113 - - - K - - - transcriptional regulator (TetR family)
NGPDNALK_01314 1.38e-233 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
NGPDNALK_01315 8.51e-148 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_01316 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_01317 4.81e-50 - - - - - - - -
NGPDNALK_01318 1.36e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
NGPDNALK_01319 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NGPDNALK_01320 3.11e-220 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
NGPDNALK_01321 2.6e-33 - - - - - - - -
NGPDNALK_01322 2.83e-144 - - - - - - - -
NGPDNALK_01323 3.01e-274 yttB - - EGP - - - Major Facilitator
NGPDNALK_01324 9.3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
NGPDNALK_01325 8.57e-114 - - - - - - - -
NGPDNALK_01326 2.39e-139 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NGPDNALK_01327 0.0 - - - S - - - Putative peptidoglycan binding domain
NGPDNALK_01328 7.85e-21 - - - - - - - -
NGPDNALK_01329 6.67e-158 - - - M - - - ErfK YbiS YcfS YnhG
NGPDNALK_01331 9.2e-130 - - - - - - - -
NGPDNALK_01332 2.68e-275 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NGPDNALK_01333 8.55e-187 - - - S - - - Alpha beta hydrolase
NGPDNALK_01334 7.78e-97 - - - L - - - nuclease
NGPDNALK_01335 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
NGPDNALK_01336 1.93e-266 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NGPDNALK_01337 2.05e-185 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
NGPDNALK_01338 0.0 snf - - KL - - - domain protein
NGPDNALK_01340 1.95e-51 - - - - ko:K18829 - ko00000,ko02048 -
NGPDNALK_01341 4.2e-88 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
NGPDNALK_01343 2.98e-163 - - - O - - - Bacterial dnaA protein
NGPDNALK_01344 6.52e-272 - - - L - - - Integrase core domain
NGPDNALK_01345 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
NGPDNALK_01348 8.53e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NGPDNALK_01349 1.78e-57 - - - K - - - HxlR-like helix-turn-helix
NGPDNALK_01350 1.81e-78 - - - S - - - macrophage migration inhibitory factor
NGPDNALK_01351 1.85e-214 - - - C - - - Oxidoreductase
NGPDNALK_01354 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
NGPDNALK_01355 4.13e-190 - - - S - - - Calcineurin-like phosphoesterase
NGPDNALK_01358 2.21e-143 - - - - - - - -
NGPDNALK_01359 0.0 - - - EGP - - - Major Facilitator
NGPDNALK_01360 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
NGPDNALK_01361 1.1e-171 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
NGPDNALK_01362 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
NGPDNALK_01363 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NGPDNALK_01364 1.58e-198 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NGPDNALK_01365 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
NGPDNALK_01366 1.16e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
NGPDNALK_01369 8.04e-129 - - - S ko:K07002 - ko00000 Serine hydrolase
NGPDNALK_01370 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
NGPDNALK_01371 5.87e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NGPDNALK_01373 9.77e-230 ydhF - - S - - - Aldo keto reductase
NGPDNALK_01374 9.58e-112 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
NGPDNALK_01375 0.0 - - - L - - - Helicase C-terminal domain protein
NGPDNALK_01377 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
NGPDNALK_01378 2.84e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
NGPDNALK_01379 7.41e-163 - - - - - - - -
NGPDNALK_01380 3.76e-161 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
NGPDNALK_01381 0.0 cadA - - P - - - P-type ATPase
NGPDNALK_01382 4.98e-272 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NGPDNALK_01383 4.52e-96 ywnA - - K - - - Transcriptional regulator
NGPDNALK_01384 5.08e-207 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
NGPDNALK_01385 5.77e-140 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NGPDNALK_01386 1.68e-179 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_01387 1.13e-137 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
NGPDNALK_01388 3.14e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
NGPDNALK_01389 7.59e-56 - - - L - - - Transposase
NGPDNALK_01391 1.28e-53 - - - M - - - family 8
NGPDNALK_01392 5.31e-139 - - - M - - - transferase activity, transferring glycosyl groups
NGPDNALK_01393 1.77e-205 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
NGPDNALK_01394 4.23e-247 - - - M - - - transferase activity, transferring glycosyl groups
NGPDNALK_01395 3.53e-269 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
NGPDNALK_01396 4.47e-199 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
NGPDNALK_01397 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NGPDNALK_01398 2.86e-286 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NGPDNALK_01399 1.75e-243 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NGPDNALK_01402 3.36e-83 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
NGPDNALK_01403 9.43e-316 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
NGPDNALK_01405 2.6e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
NGPDNALK_01406 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NGPDNALK_01407 1.16e-315 yycH - - S - - - YycH protein
NGPDNALK_01408 5.03e-193 yycI - - S - - - YycH protein
NGPDNALK_01409 2.94e-195 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
NGPDNALK_01410 2.46e-289 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
NGPDNALK_01411 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
NGPDNALK_01412 2.08e-26 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
NGPDNALK_01413 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NGPDNALK_01414 1.1e-125 - - - S - - - reductase
NGPDNALK_01415 6.23e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
NGPDNALK_01416 9.88e-66 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NGPDNALK_01417 4.77e-57 - - - S - - - Glycosyltransferase like family 2
NGPDNALK_01418 1.56e-32 - - - M - - - Glycosyltransferase, group 2 family protein
NGPDNALK_01419 4.77e-36 - - - M - - - PFAM Glycosyl transferase family 2
NGPDNALK_01420 1.11e-32 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
NGPDNALK_01421 1.99e-85 cps2I - - S - - - Psort location CytoplasmicMembrane, score
NGPDNALK_01423 3.16e-49 - - - M - - - Glycosyltransferase GT-D fold
NGPDNALK_01424 8.32e-82 wefC - - M - - - Stealth protein CR2, conserved region 2
NGPDNALK_01425 3.03e-104 - - GT4 G ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like domain
NGPDNALK_01426 2.35e-62 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
NGPDNALK_01427 3.01e-140 ywqD - - D - - - Capsular exopolysaccharide family
NGPDNALK_01428 6.16e-126 epsB - - M - - - biosynthesis protein
NGPDNALK_01429 5.74e-258 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NGPDNALK_01430 4.97e-174 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NGPDNALK_01431 1.38e-140 - - - S - - - Peptidase propeptide and YPEB domain
NGPDNALK_01432 2.4e-312 - - - T - - - GHKL domain
NGPDNALK_01433 2.13e-158 - - - T - - - Transcriptional regulatory protein, C terminal
NGPDNALK_01434 7.05e-56 - - - S ko:K07088 - ko00000 Membrane transport protein
NGPDNALK_01436 1.45e-10 - - - S - - - Bacteriocin class II with double-glycine leader peptide
NGPDNALK_01439 2.25e-163 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
NGPDNALK_01440 5.09e-153 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
NGPDNALK_01441 1.97e-28 - - - - - - - -
NGPDNALK_01442 2.47e-112 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
NGPDNALK_01443 2.29e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
NGPDNALK_01444 3.61e-61 - - - - - - - -
NGPDNALK_01445 1.95e-109 uspA - - T - - - universal stress protein
NGPDNALK_01446 3.44e-261 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
NGPDNALK_01447 4.01e-199 yvgN - - S - - - Aldo keto reductase
NGPDNALK_01448 3.33e-121 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
NGPDNALK_01449 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
NGPDNALK_01450 1.91e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NGPDNALK_01451 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
NGPDNALK_01452 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NGPDNALK_01453 4.04e-219 eriC - - P ko:K03281 - ko00000 chloride
NGPDNALK_01454 4.76e-35 eriC - - P ko:K03281 - ko00000 chloride
NGPDNALK_01455 1.68e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
NGPDNALK_01456 1.06e-139 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
NGPDNALK_01457 2.44e-244 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NGPDNALK_01458 1.9e-194 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NGPDNALK_01459 5.14e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NGPDNALK_01460 5.93e-281 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
NGPDNALK_01461 5.98e-55 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
NGPDNALK_01462 1.91e-150 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NGPDNALK_01463 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
NGPDNALK_01464 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NGPDNALK_01466 2.48e-49 - - - L - - - Transposase, IS116 IS110 IS902 family
NGPDNALK_01467 2.47e-250 eriC - - P ko:K03281 - ko00000 chloride
NGPDNALK_01468 4.11e-256 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NGPDNALK_01469 0.0 - - - L - - - DNA helicase
NGPDNALK_01470 1.17e-105 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
NGPDNALK_01471 5.96e-241 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
NGPDNALK_01472 2.26e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
NGPDNALK_01473 1.03e-213 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
NGPDNALK_01474 3.92e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
NGPDNALK_01475 3.66e-226 - - - - - - - -
NGPDNALK_01476 1.69e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
NGPDNALK_01478 1.52e-204 yunF - - F - - - Protein of unknown function DUF72
NGPDNALK_01479 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NGPDNALK_01480 3.73e-200 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
NGPDNALK_01481 1.42e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NGPDNALK_01482 6.45e-209 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NGPDNALK_01483 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
NGPDNALK_01484 2.44e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NGPDNALK_01485 2.02e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NGPDNALK_01486 9.8e-158 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
NGPDNALK_01487 3.54e-165 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
NGPDNALK_01488 5.24e-191 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
NGPDNALK_01489 3.17e-314 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NGPDNALK_01490 9.36e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NGPDNALK_01491 6.01e-101 - - - - - - - -
NGPDNALK_01492 4.65e-190 yidA - - S - - - hydrolase
NGPDNALK_01493 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
NGPDNALK_01494 1.13e-186 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
NGPDNALK_01495 9.28e-89 ywiB - - S - - - Domain of unknown function (DUF1934)
NGPDNALK_01496 1.04e-85 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NGPDNALK_01497 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NGPDNALK_01498 2.62e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NGPDNALK_01499 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
NGPDNALK_01500 1.59e-303 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NGPDNALK_01501 6.49e-213 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
NGPDNALK_01502 1.01e-160 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NGPDNALK_01503 5.83e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NGPDNALK_01504 9.19e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
NGPDNALK_01505 1.06e-154 - - - G - - - Belongs to the phosphoglycerate mutase family
NGPDNALK_01506 6.66e-113 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NGPDNALK_01507 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
NGPDNALK_01508 2.61e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
NGPDNALK_01509 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NGPDNALK_01510 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NGPDNALK_01511 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
NGPDNALK_01512 5.99e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NGPDNALK_01513 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NGPDNALK_01514 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGPDNALK_01515 9.07e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
NGPDNALK_01516 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NGPDNALK_01517 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
NGPDNALK_01518 1.61e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NGPDNALK_01519 7.62e-270 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NGPDNALK_01520 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
NGPDNALK_01521 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NGPDNALK_01522 1.25e-305 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
NGPDNALK_01523 1.14e-185 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
NGPDNALK_01524 3.84e-145 - - - S - - - (CBS) domain
NGPDNALK_01525 5.62e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NGPDNALK_01526 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NGPDNALK_01527 1.01e-52 yabO - - J - - - S4 domain protein
NGPDNALK_01528 1.23e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
NGPDNALK_01529 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
NGPDNALK_01530 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NGPDNALK_01531 3.68e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NGPDNALK_01532 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NGPDNALK_01533 3.1e-216 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NGPDNALK_01534 2.53e-240 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NGPDNALK_01535 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
NGPDNALK_01536 5.01e-68 entB - - Q - - - Isochorismatase family
NGPDNALK_01537 5.39e-64 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
NGPDNALK_01538 6.78e-81 - - - S - - - Protein of unknown function (DUF1700)
NGPDNALK_01539 2e-70 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
NGPDNALK_01540 4.09e-196 - - - K - - - Transcriptional regulator, LysR family
NGPDNALK_01541 3.16e-313 - - - E - - - Peptidase family M20/M25/M40
NGPDNALK_01542 2.06e-278 - - - G - - - Transporter, major facilitator family protein
NGPDNALK_01543 1.3e-262 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NGPDNALK_01546 5.45e-177 - - - L ko:K07455 - ko00000,ko03400 RecT family
NGPDNALK_01547 3.39e-175 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
NGPDNALK_01548 1.29e-05 - - - L - - - HNH nucleases
NGPDNALK_01549 1.03e-68 - - - L - - - Psort location Cytoplasmic, score
NGPDNALK_01550 4.45e-70 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
NGPDNALK_01555 3.43e-25 - - - - - - - -
NGPDNALK_01559 1.84e-41 - - - V - - - NUMOD4 motif
NGPDNALK_01562 4.94e-23 - - - - - - - -
NGPDNALK_01563 6.03e-79 rusA - - L - - - Endodeoxyribonuclease RusA
NGPDNALK_01569 1.53e-256 pbuG - - S ko:K06901 - ko00000,ko02000 permease
NGPDNALK_01570 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
NGPDNALK_01571 1.78e-230 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
NGPDNALK_01572 2.97e-124 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
NGPDNALK_01573 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NGPDNALK_01574 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
NGPDNALK_01575 2.59e-175 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
NGPDNALK_01576 2.41e-179 - - - S - - - Membrane
NGPDNALK_01577 4.73e-97 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
NGPDNALK_01578 6.94e-167 - - - F - - - glutamine amidotransferase
NGPDNALK_01579 1.32e-80 - - - - - - - -
NGPDNALK_01580 4.5e-202 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NGPDNALK_01581 2.4e-180 - - - K - - - Transcriptional regulator
NGPDNALK_01582 9.44e-234 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
NGPDNALK_01583 1.88e-210 ypuA - - S - - - Protein of unknown function (DUF1002)
NGPDNALK_01584 1.94e-290 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
NGPDNALK_01585 1.32e-222 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
NGPDNALK_01586 1.63e-193 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
NGPDNALK_01587 1.87e-187 - - - S - - - Alpha beta hydrolase
NGPDNALK_01588 7.07e-83 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
NGPDNALK_01589 4.11e-223 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NGPDNALK_01590 1.46e-196 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NGPDNALK_01591 1.29e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
NGPDNALK_01592 8.42e-149 yjbH - - Q - - - Thioredoxin
NGPDNALK_01593 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NGPDNALK_01594 5.93e-265 coiA - - S ko:K06198 - ko00000 Competence protein
NGPDNALK_01595 9.02e-154 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NGPDNALK_01596 2.02e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NGPDNALK_01597 3.75e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
NGPDNALK_01618 8.31e-71 - 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NGPDNALK_01619 8.92e-106 - - - M - - - glycosyl transferase group 1
NGPDNALK_01620 2.11e-202 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Psort location Cytoplasmic, score 8.87
NGPDNALK_01621 1.29e-56 - - - S - - - Glycosyltransferase like family 2
NGPDNALK_01622 6.2e-133 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
NGPDNALK_01623 6.05e-153 ywqD - - D - - - Capsular exopolysaccharide family
NGPDNALK_01624 2.17e-188 epsB - - M - - - biosynthesis protein
NGPDNALK_01625 1.56e-213 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
NGPDNALK_01626 3.78e-88 - - - K - - - Transcriptional regulator, HxlR family
NGPDNALK_01627 1.74e-164 - - - - - - - -
NGPDNALK_01628 1e-132 - - - K - - - DNA-templated transcription, initiation
NGPDNALK_01629 1.61e-48 - - - - - - - -
NGPDNALK_01630 1.36e-135 yocS - - S ko:K03453 - ko00000 SBF-like CPA transporter family (DUF4137)
NGPDNALK_01631 1.13e-163 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NGPDNALK_01632 1.12e-102 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NGPDNALK_01633 1.02e-294 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NGPDNALK_01634 2.06e-260 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NGPDNALK_01635 9.41e-261 - - - G - - - Major Facilitator Superfamily
NGPDNALK_01636 3.06e-198 menH 4.2.99.20 - I ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NGPDNALK_01637 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NGPDNALK_01638 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 chorismate binding enzyme
NGPDNALK_01639 2.21e-31 - - - - - - - -
NGPDNALK_01640 1.11e-75 - - - S - - - Siphovirus Gp157
NGPDNALK_01641 8.12e-200 - - - L - - - Helicase C-terminal domain protein
NGPDNALK_01642 1.49e-111 - - - L - - - AAA domain
NGPDNALK_01643 1.34e-38 - - - - - - - -
NGPDNALK_01644 6.27e-105 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
NGPDNALK_01645 4.04e-148 - - - S ko:K06919 - ko00000 Virulence-associated protein E
NGPDNALK_01647 2.13e-77 - - - S - - - VRR_NUC
NGPDNALK_01649 1.11e-30 - - - - - - - -
NGPDNALK_01652 1.83e-101 - - - - - - - -
NGPDNALK_01656 1.11e-106 - - - - - - - -
NGPDNALK_01657 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NGPDNALK_01658 1.1e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
NGPDNALK_01659 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
NGPDNALK_01660 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NGPDNALK_01662 4.26e-88 - - - J - - - Domain of unknown function (DUF4041)
NGPDNALK_01663 1.56e-113 - - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_01664 1.38e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
NGPDNALK_01665 4.68e-152 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NGPDNALK_01666 4.31e-296 - - - P - - - Chloride transporter, ClC family
NGPDNALK_01667 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
NGPDNALK_01668 5.65e-143 - - - I - - - Acid phosphatase homologues
NGPDNALK_01670 3.45e-88 - - - K - - - Bacterial regulatory proteins, tetR family
NGPDNALK_01671 9.67e-49 - - - S - - - Domain of unknown function (DUF4440)
NGPDNALK_01672 4.45e-185 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
NGPDNALK_01673 1.94e-46 qacA - - EGP - - - Fungal trichothecene efflux pump (TRI12)
NGPDNALK_01674 2.95e-52 - - - S - - - Hexapeptide repeat of succinyl-transferase
NGPDNALK_01675 2.19e-159 - - - C - - - Aldo keto reductase
NGPDNALK_01676 8.03e-113 - - - GM - - - NAD(P)H-binding
NGPDNALK_01677 8.65e-176 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
NGPDNALK_01678 1.88e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NGPDNALK_01679 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NGPDNALK_01680 5.61e-71 - - - - - - - -
NGPDNALK_01681 5.13e-162 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NGPDNALK_01682 8.04e-230 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
NGPDNALK_01683 6.77e-77 - - - - - - - -
NGPDNALK_01684 3.37e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NGPDNALK_01685 4.3e-256 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
NGPDNALK_01686 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
NGPDNALK_01687 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NGPDNALK_01688 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NGPDNALK_01689 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
NGPDNALK_01690 8.1e-118 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NGPDNALK_01691 4.58e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NGPDNALK_01692 1.26e-84 - - - - - - - -
NGPDNALK_01693 7.37e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
NGPDNALK_01694 9.98e-215 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NGPDNALK_01695 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NGPDNALK_01696 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NGPDNALK_01697 1.96e-65 ylxQ - - J - - - ribosomal protein
NGPDNALK_01698 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
NGPDNALK_01699 1.38e-273 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
NGPDNALK_01700 5.44e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
NGPDNALK_01701 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NGPDNALK_01702 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NGPDNALK_01703 1.15e-298 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
NGPDNALK_01704 2.37e-177 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
NGPDNALK_01705 1.29e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NGPDNALK_01706 1.72e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NGPDNALK_01707 1.81e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
NGPDNALK_01708 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NGPDNALK_01709 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
NGPDNALK_01710 4.85e-232 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NGPDNALK_01711 1.32e-62 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
NGPDNALK_01712 1.69e-181 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
NGPDNALK_01713 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
NGPDNALK_01714 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
NGPDNALK_01715 2.22e-46 ynzC - - S - - - UPF0291 protein
NGPDNALK_01716 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NGPDNALK_01717 1.66e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
NGPDNALK_01718 5.93e-163 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NGPDNALK_01720 1.66e-20 - - - - - - - -
NGPDNALK_01721 2.41e-26 - - - S - - - Phage gp6-like head-tail connector protein
NGPDNALK_01722 1.88e-231 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
NGPDNALK_01723 1.64e-179 - - - S - - - Phage portal protein
NGPDNALK_01724 1.52e-252 terL - - S - - - overlaps another CDS with the same product name
NGPDNALK_01725 4.11e-29 terS - - L - - - Phage terminase, small subunit
NGPDNALK_01726 1.01e-39 - - - L - - - HNH endonuclease
NGPDNALK_01729 2.05e-110 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
NGPDNALK_01730 1.46e-46 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
NGPDNALK_01735 3.25e-08 - - - S - - - Helix-turn-helix domain
NGPDNALK_01736 0.000772 - - - L - - - GIY-YIG catalytic domain
NGPDNALK_01737 1.09e-66 - - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_01738 3.77e-123 - - - - - - - -
NGPDNALK_01739 2.94e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NGPDNALK_01740 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
NGPDNALK_01741 3.87e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
NGPDNALK_01742 2.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NGPDNALK_01743 3.8e-316 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NGPDNALK_01744 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NGPDNALK_01745 2.44e-20 - - - - - - - -
NGPDNALK_01746 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
NGPDNALK_01747 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
NGPDNALK_01748 5.9e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NGPDNALK_01749 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NGPDNALK_01750 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NGPDNALK_01751 2.32e-204 - - - S - - - Tetratricopeptide repeat
NGPDNALK_01752 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NGPDNALK_01753 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NGPDNALK_01754 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
NGPDNALK_01755 5.37e-192 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
NGPDNALK_01756 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
NGPDNALK_01757 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
NGPDNALK_01758 1.97e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
NGPDNALK_01759 6.33e-254 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
NGPDNALK_01760 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NGPDNALK_01761 7.94e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
NGPDNALK_01762 5.25e-59 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
NGPDNALK_01763 1.85e-284 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
NGPDNALK_01764 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
NGPDNALK_01765 4.1e-176 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
NGPDNALK_01766 5.79e-62 yktA - - S - - - Belongs to the UPF0223 family
NGPDNALK_01767 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
NGPDNALK_01768 2.13e-311 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NGPDNALK_01769 3.28e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
NGPDNALK_01770 9.95e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
NGPDNALK_01771 2.38e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NGPDNALK_01772 8.99e-104 - - - - - - - -
NGPDNALK_01773 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
NGPDNALK_01774 1.45e-230 - - - I - - - Diacylglycerol kinase catalytic
NGPDNALK_01775 7.27e-38 - - - - - - - -
NGPDNALK_01776 1.84e-234 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
NGPDNALK_01777 4.13e-147 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NGPDNALK_01779 1.13e-40 - - - S - - - GyrI-like small molecule binding domain
NGPDNALK_01780 4.04e-87 - - - S - - - GyrI-like small molecule binding domain
NGPDNALK_01781 2.21e-155 - - - S ko:K07507 - ko00000,ko02000 MgtC family
NGPDNALK_01782 4.83e-118 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
NGPDNALK_01783 9.27e-245 flp - - V - - - Beta-lactamase
NGPDNALK_01784 1.03e-96 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NGPDNALK_01785 6.28e-116 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
NGPDNALK_01786 5.25e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
NGPDNALK_01787 9.98e-24 - - - - - - - -
NGPDNALK_01788 1.58e-28 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
NGPDNALK_01792 1.41e-169 bioA 2.6.1.62 - H ko:K00833 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NGPDNALK_01793 3.2e-05 - - - S ko:K16922 - ko00000,ko01002 Psort location CytoplasmicMembrane, score 10.00
NGPDNALK_01794 2.43e-93 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
NGPDNALK_01795 3.62e-46 - - - - - - - -
NGPDNALK_01796 1.45e-72 - - - - - - - -
NGPDNALK_01797 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
NGPDNALK_01798 9.97e-143 - - - L ko:K07497 - ko00000 hmm pf00665
NGPDNALK_01800 9.13e-124 - - - - - - - -
NGPDNALK_01801 3.32e-76 - - - - - - - -
NGPDNALK_01802 9.95e-36 - - - - - - - -
NGPDNALK_01803 1.44e-191 - - - G - - - Belongs to the phosphoglycerate mutase family
NGPDNALK_01804 4.8e-159 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NGPDNALK_01805 8.29e-133 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
NGPDNALK_01806 3.69e-92 - - - - - - - -
NGPDNALK_01807 1.5e-102 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
NGPDNALK_01808 2.91e-186 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
NGPDNALK_01809 5.05e-125 - - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
NGPDNALK_01810 1.33e-170 - 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
NGPDNALK_01811 9.98e-161 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
NGPDNALK_01812 1.44e-195 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
NGPDNALK_01813 1.29e-231 - - - G - - - Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NGPDNALK_01815 2.84e-109 flp - - V - - - Beta-lactamase
NGPDNALK_01816 2.25e-70 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
NGPDNALK_01817 7.88e-211 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
NGPDNALK_01818 1.67e-107 - - - C - - - Flavodoxin
NGPDNALK_01819 1.19e-200 lysR - - K - - - Transcriptional regulator
NGPDNALK_01820 2.26e-59 - - - - - - - -
NGPDNALK_01824 7.3e-28 - - - V - - - Abi-like protein
NGPDNALK_01825 4.04e-179 int2 - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_01827 4.77e-65 yrvD - - S - - - Pfam:DUF1049
NGPDNALK_01828 1.54e-189 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NGPDNALK_01829 3.29e-183 - - - M - - - Glycosyl transferase family 2
NGPDNALK_01830 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NGPDNALK_01832 5.37e-74 - - - S - - - Pfam:DUF59
NGPDNALK_01833 8.25e-250 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NGPDNALK_01834 3e-113 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NGPDNALK_01835 2.42e-116 - - - L - - - Integrase
NGPDNALK_01836 6.01e-17 XK27_09155 - - K - - - Transcriptional
NGPDNALK_01837 6.26e-96 - - - - - - - -
NGPDNALK_01838 2.74e-285 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
NGPDNALK_01839 1.87e-176 - - - V - - - Beta-lactamase enzyme family
NGPDNALK_01840 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
NGPDNALK_01841 2.2e-272 - - - EGP - - - Transporter, major facilitator family protein
NGPDNALK_01842 0.0 arcT - - E - - - Dipeptidase
NGPDNALK_01843 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
NGPDNALK_01844 1.27e-219 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
NGPDNALK_01845 9.13e-158 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
NGPDNALK_01846 8.91e-141 - - - I - - - alpha/beta hydrolase fold
NGPDNALK_01847 3.23e-211 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
NGPDNALK_01848 1.1e-218 - - - S - - - Conserved hypothetical protein 698
NGPDNALK_01849 1.53e-107 - - - S - - - NADPH-dependent FMN reductase
NGPDNALK_01850 1.26e-214 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
NGPDNALK_01851 1.14e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
NGPDNALK_01852 2.3e-294 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
NGPDNALK_01853 3.77e-114 - - - Q - - - Methyltransferase
NGPDNALK_01854 2.8e-152 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
NGPDNALK_01855 1.59e-303 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
NGPDNALK_01856 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
NGPDNALK_01857 2.31e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
NGPDNALK_01858 7.46e-212 - - - G - - - Glycosyl hydrolases family 8
NGPDNALK_01859 2.67e-266 - - - M - - - Glycosyl transferase
NGPDNALK_01861 1.37e-152 - - - - - - - -
NGPDNALK_01862 1.32e-277 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
NGPDNALK_01863 2.89e-160 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
NGPDNALK_01864 3.02e-175 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NGPDNALK_01865 7.4e-197 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
NGPDNALK_01866 3.23e-194 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
NGPDNALK_01867 1.11e-201 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
NGPDNALK_01868 7.17e-171 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
NGPDNALK_01869 6.63e-174 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
NGPDNALK_01870 1.93e-182 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
NGPDNALK_01871 2.61e-235 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
NGPDNALK_01872 4.2e-96 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NGPDNALK_01873 1.79e-55 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NGPDNALK_01874 2.25e-207 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NGPDNALK_01875 2.42e-146 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NGPDNALK_01876 1.97e-168 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NGPDNALK_01877 2.54e-101 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NGPDNALK_01878 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Amidohydrolase family
NGPDNALK_01879 2.83e-84 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease beta subunit
NGPDNALK_01880 4.88e-60 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease, gamma subunit
NGPDNALK_01881 9.52e-124 - - - S - - - AmiS/UreI family transporter
NGPDNALK_01882 1.06e-276 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
NGPDNALK_01884 6.13e-216 - - - - - - - -
NGPDNALK_01885 3.04e-122 - - - K - - - acetyltransferase
NGPDNALK_01886 4.68e-90 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
NGPDNALK_01888 1.18e-221 - - - - - - - -
NGPDNALK_01889 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NGPDNALK_01890 3.47e-233 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
NGPDNALK_01891 5.58e-249 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
NGPDNALK_01892 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
NGPDNALK_01894 1.84e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NGPDNALK_01895 9.38e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NGPDNALK_01896 2.9e-157 - - - O - - - Zinc-dependent metalloprotease
NGPDNALK_01897 7.26e-146 - - - S - - - Membrane
NGPDNALK_01898 3.12e-250 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
NGPDNALK_01899 3.64e-116 - - - S - - - Domain of unknown function (DUF4767)
NGPDNALK_01900 3.7e-19 - - - - - - - -
NGPDNALK_01901 2.72e-250 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
NGPDNALK_01902 6.95e-122 - - - K - - - PFAM GCN5-related N-acetyltransferase
NGPDNALK_01903 2.18e-217 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
NGPDNALK_01904 2.32e-104 - - - - - - - -
NGPDNALK_01905 4.74e-164 - - - M - - - Lysin motif
NGPDNALK_01906 1.55e-254 - - - EGP - - - Major Facilitator
NGPDNALK_01907 3.62e-131 ywlG - - S - - - Belongs to the UPF0340 family
NGPDNALK_01908 1.71e-252 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
NGPDNALK_01909 7.66e-103 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
NGPDNALK_01910 3.4e-196 - - - J - - - Methyltransferase
NGPDNALK_01911 1.87e-43 - - - L - - - PFAM Integrase catalytic region
NGPDNALK_01912 2.59e-145 - - - S ko:K07118 - ko00000 NAD(P)H-binding
NGPDNALK_01913 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
NGPDNALK_01914 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
NGPDNALK_01915 1.69e-233 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NGPDNALK_01916 1.32e-62 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
NGPDNALK_01917 1.83e-72 - - - - - - - -
NGPDNALK_01918 1.51e-148 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
NGPDNALK_01919 4e-208 - - - I - - - alpha/beta hydrolase fold
NGPDNALK_01920 3.67e-81 - - - L ko:K07497 - ko00000 hmm pf00665
NGPDNALK_01921 3.08e-168 - - - L - - - Transposase
NGPDNALK_01922 0.0 - - - O - - - Arylsulfotransferase (ASST)
NGPDNALK_01923 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NGPDNALK_01924 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NGPDNALK_01925 6.37e-22 - - - - - - - -
NGPDNALK_01927 7.31e-40 - - - K - - - Transcriptional regulator, Cro CI family
NGPDNALK_01928 8.06e-36 - - - - - - - -
NGPDNALK_01929 1.99e-264 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NGPDNALK_01930 9.26e-139 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NGPDNALK_01931 1.3e-204 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NGPDNALK_01932 1.01e-170 - - - O - - - Bacterial dnaA protein
NGPDNALK_01933 1.11e-302 - - - L - - - Integrase core domain
NGPDNALK_01935 7e-158 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
NGPDNALK_01937 3.68e-31 - - - S - - - Acyltransferase family
NGPDNALK_01938 6.82e-96 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
NGPDNALK_01942 3.55e-20 - - - K - - - Cro/C1-type HTH DNA-binding domain
NGPDNALK_01943 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NGPDNALK_01944 0.0 - - - E ko:K03294 - ko00000 amino acid
NGPDNALK_01945 7.76e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
NGPDNALK_01946 2.96e-116 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NGPDNALK_01947 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
NGPDNALK_01948 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
NGPDNALK_01949 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NGPDNALK_01950 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NGPDNALK_01951 9.45e-282 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NGPDNALK_01952 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
NGPDNALK_01953 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NGPDNALK_01954 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
NGPDNALK_01955 1.51e-237 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NGPDNALK_01956 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NGPDNALK_01957 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
NGPDNALK_01958 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
NGPDNALK_01959 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
NGPDNALK_01960 8.12e-158 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
NGPDNALK_01961 1.5e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
NGPDNALK_01962 1.03e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NGPDNALK_01963 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
NGPDNALK_01964 3.5e-167 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
NGPDNALK_01965 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NGPDNALK_01966 2.12e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NGPDNALK_01967 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NGPDNALK_01968 1.17e-268 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NGPDNALK_01969 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NGPDNALK_01970 4.37e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
NGPDNALK_01971 7.4e-71 - - - - - - - -
NGPDNALK_01972 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
NGPDNALK_01973 2.25e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
NGPDNALK_01974 1.97e-191 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
NGPDNALK_01975 3.54e-198 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
NGPDNALK_01976 2.83e-58 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NGPDNALK_01977 1.09e-309 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NGPDNALK_01978 6.56e-192 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NGPDNALK_01979 2.24e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NGPDNALK_01980 1.32e-92 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
NGPDNALK_01981 1.86e-142 - - - J - - - 2'-5' RNA ligase superfamily
NGPDNALK_01982 4.13e-254 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
NGPDNALK_01983 4.82e-164 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NGPDNALK_01984 7.2e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
NGPDNALK_01985 5.08e-72 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
NGPDNALK_01986 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
NGPDNALK_01987 5.7e-146 - - - K - - - Transcriptional regulator
NGPDNALK_01990 1.93e-112 - - - S - - - Protein conserved in bacteria
NGPDNALK_01991 1.26e-224 - - - - - - - -
NGPDNALK_01992 4e-202 - - - - - - - -
NGPDNALK_01993 4.41e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
NGPDNALK_01994 9.48e-130 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NGPDNALK_02001 4.77e-37 - - - M - - - Bacteriophage peptidoglycan hydrolase
NGPDNALK_02003 1.17e-220 - - - U - - - type IV secretory pathway VirB4
NGPDNALK_02007 3.21e-228 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
NGPDNALK_02012 4.42e-180 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NGPDNALK_02014 7.04e-162 topA2 5.99.1.2 - G ko:K03169 - ko00000,ko01000,ko03032 Topoisomerase IA
NGPDNALK_02015 6.76e-63 - - - L - - - Protein of unknown function (DUF3991)
NGPDNALK_02017 1.17e-34 - - - D - - - Glucan-binding protein C
NGPDNALK_02019 2.05e-120 - - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_02022 1.13e-50 - - - L ko:K07484 - ko00000 Transposase IS66 family
NGPDNALK_02023 7.2e-63 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
NGPDNALK_02025 6.98e-137 - - - L - - - Helix-turn-helix domain
NGPDNALK_02026 4.29e-179 - - - L ko:K07497 - ko00000 hmm pf00665
NGPDNALK_02028 0.0 - - - S - - - Uncharacterised protein family (UPF0236)
NGPDNALK_02029 2.41e-98 - - - S - - - Uncharacterised protein family (UPF0236)
NGPDNALK_02030 7.09e-131 - - - S - - - Uncharacterised protein family (UPF0236)
NGPDNALK_02031 2.4e-37 - - - - - - - -
NGPDNALK_02032 1.05e-254 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
NGPDNALK_02033 4.89e-57 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
NGPDNALK_02034 1.44e-132 int2 - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_02035 6.94e-75 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NGPDNALK_02036 6.56e-223 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NGPDNALK_02037 1.72e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
NGPDNALK_02038 3.23e-75 - - - S - - - Small secreted protein
NGPDNALK_02039 2.95e-75 ytpP - - CO - - - Thioredoxin
NGPDNALK_02040 1.34e-151 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NGPDNALK_02041 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
NGPDNALK_02042 6.21e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
NGPDNALK_02043 2.05e-155 - - - S - - - Protein of unknown function (DUF1275)
NGPDNALK_02044 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NGPDNALK_02045 9.85e-198 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NGPDNALK_02046 3.99e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NGPDNALK_02047 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NGPDNALK_02048 3.61e-303 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
NGPDNALK_02049 6.05e-222 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
NGPDNALK_02050 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NGPDNALK_02051 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
NGPDNALK_02052 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NGPDNALK_02053 7.78e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
NGPDNALK_02054 1.82e-277 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
NGPDNALK_02055 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
NGPDNALK_02056 4.9e-158 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NGPDNALK_02057 1.46e-145 yqeK - - H - - - Hydrolase, HD family
NGPDNALK_02058 2.69e-79 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NGPDNALK_02059 1.02e-175 yqeM - - Q - - - Methyltransferase
NGPDNALK_02060 6.82e-274 ylbM - - S - - - Belongs to the UPF0348 family
NGPDNALK_02061 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
NGPDNALK_02062 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
NGPDNALK_02063 9.72e-156 csrR - - K - - - response regulator
NGPDNALK_02064 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
NGPDNALK_02065 0.0 potE - - E - - - Amino Acid
NGPDNALK_02066 1.74e-291 - - - V - - - MatE
NGPDNALK_02067 3.32e-93 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
NGPDNALK_02068 1.11e-214 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NGPDNALK_02069 2.45e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
NGPDNALK_02070 2.71e-186 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NGPDNALK_02071 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NGPDNALK_02072 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
NGPDNALK_02073 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NGPDNALK_02074 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NGPDNALK_02075 5.46e-145 - - - M - - - PFAM NLP P60 protein
NGPDNALK_02076 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
NGPDNALK_02077 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NGPDNALK_02078 9.37e-92 yneR - - S - - - Belongs to the HesB IscA family
NGPDNALK_02079 0.0 - - - S - - - membrane
NGPDNALK_02080 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
NGPDNALK_02081 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
NGPDNALK_02082 6.32e-128 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NGPDNALK_02083 1.13e-145 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
NGPDNALK_02084 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
NGPDNALK_02085 2.51e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
NGPDNALK_02086 7.66e-88 yqhL - - P - - - Rhodanese-like protein
NGPDNALK_02087 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
NGPDNALK_02088 4.12e-226 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NGPDNALK_02089 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
NGPDNALK_02090 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NGPDNALK_02091 1.7e-282 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
NGPDNALK_02092 1.28e-18 - - - - - - - -
NGPDNALK_02093 1.39e-196 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
NGPDNALK_02096 2.57e-93 - - - L - - - Belongs to the 'phage' integrase family
NGPDNALK_02098 3.19e-21 - - - K - - - Peptidase S24-like
NGPDNALK_02102 2.13e-08 - - - L - - - Psort location Cytoplasmic, score
NGPDNALK_02117 3.49e-05 - - - S - - - YopX protein
NGPDNALK_02124 3.69e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
NGPDNALK_02131 4.01e-64 - - - L - - - four-way junction helicase activity
NGPDNALK_02133 2.04e-68 - - - - - - - -
NGPDNALK_02135 2.07e-44 lytE - - M - - - Lysin motif
NGPDNALK_02138 4.41e-124 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NGPDNALK_02140 7.72e-49 ytpP - - CO - - - Thioredoxin
NGPDNALK_02141 3.92e-52 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
NGPDNALK_02143 1.01e-122 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 dithiol-disulfide isomerase involved in polyketide biosynthesis
NGPDNALK_02144 8.86e-177 trxB 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Glucose inhibited division protein A
NGPDNALK_02145 2.9e-33 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
NGPDNALK_02146 3.3e-91 M1-798 - - K - - - Rhodanese Homology Domain
NGPDNALK_02147 9.04e-56 - - - K - - - HxlR-like helix-turn-helix
NGPDNALK_02148 1.75e-179 - - - L - - - Bacterial dnaA protein
NGPDNALK_02149 3.24e-292 - - - L - - - Integrase core domain
NGPDNALK_02150 5.75e-49 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
NGPDNALK_02151 0.0 - - - L - - - PLD-like domain
NGPDNALK_02153 3.15e-229 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
NGPDNALK_02154 4.22e-244 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NGPDNALK_02155 1.18e-124 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
NGPDNALK_02156 2.16e-285 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NGPDNALK_02157 6.42e-101 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NGPDNALK_02158 1.49e-145 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
NGPDNALK_02159 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
NGPDNALK_02160 1.42e-270 - - - G - - - Transporter, major facilitator family protein
NGPDNALK_02161 1.67e-140 - - - K ko:K03091 - ko00000,ko03021 RNA polymerase sigma factor, sigma-70 family
NGPDNALK_02162 4.73e-85 yuxO - - Q - - - Thioesterase superfamily
NGPDNALK_02163 3.31e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NGPDNALK_02164 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NGPDNALK_02165 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
NGPDNALK_02166 2.32e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
NGPDNALK_02167 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
NGPDNALK_02168 1.66e-305 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
NGPDNALK_02169 9.47e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NGPDNALK_02170 4.52e-106 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
NGPDNALK_02171 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
NGPDNALK_02172 2.79e-75 - - - S - - - Iron-sulfur cluster assembly protein
NGPDNALK_02173 1.11e-204 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
NGPDNALK_02174 3.26e-144 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
NGPDNALK_02175 1.43e-51 - - - S - - - Cytochrome B5
NGPDNALK_02176 2.62e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
NGPDNALK_02177 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
NGPDNALK_02178 7.66e-192 - - - O - - - Band 7 protein
NGPDNALK_02179 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
NGPDNALK_02180 2.9e-169 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
NGPDNALK_02181 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
NGPDNALK_02182 1.78e-160 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
NGPDNALK_02183 6.86e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
NGPDNALK_02184 3.11e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
NGPDNALK_02185 3.71e-236 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
NGPDNALK_02186 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
NGPDNALK_02187 6.82e-119 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
NGPDNALK_02188 8.91e-248 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NGPDNALK_02189 1.95e-272 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
NGPDNALK_02190 5.83e-225 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
NGPDNALK_02191 1.72e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
NGPDNALK_02192 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
NGPDNALK_02193 6.66e-115 ypmB - - S - - - Protein conserved in bacteria
NGPDNALK_02194 9.68e-159 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
NGPDNALK_02195 2.32e-206 - - - EG - - - EamA-like transporter family
NGPDNALK_02196 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
NGPDNALK_02197 2.35e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NGPDNALK_02198 1.87e-132 ypsA - - S - - - Belongs to the UPF0398 family
NGPDNALK_02199 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NGPDNALK_02200 1.01e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
NGPDNALK_02201 2.94e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
NGPDNALK_02202 5.39e-92 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
NGPDNALK_02203 1.49e-84 esbA - - S - - - Family of unknown function (DUF5322)
NGPDNALK_02204 1.41e-93 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NGPDNALK_02205 7.97e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
NGPDNALK_02206 2.62e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
NGPDNALK_02207 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
NGPDNALK_02208 0.0 FbpA - - K - - - Fibronectin-binding protein
NGPDNALK_02209 2.95e-207 - - - S - - - EDD domain protein, DegV family
NGPDNALK_02210 7.18e-126 - - - - - - - -
NGPDNALK_02211 1.24e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
NGPDNALK_02212 8.83e-173 gspA - - M - - - family 8
NGPDNALK_02213 5.98e-206 - - - S - - - Alpha beta hydrolase
NGPDNALK_02214 4.52e-123 - - - K - - - Acetyltransferase (GNAT) domain
NGPDNALK_02215 1.19e-138 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NGPDNALK_02216 2.76e-63 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
NGPDNALK_02217 3.42e-50 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
NGPDNALK_02218 3.08e-211 yvgN - - C - - - Aldo keto reductase
NGPDNALK_02219 3.31e-56 - - - K - - - Transcriptional regulator

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)