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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MCLBJOKE_00001	1.29e-59	-	-	-	S	ko:K07334	-	ko00000,ko02048	RelE-like toxin of type II toxin-antitoxin system HigB
MCLBJOKE_00002	7.94e-51	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
MCLBJOKE_00003	1.01e-143	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00005	3.51e-38	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00006	2.49e-80	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00007	2.59e-138	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MCLBJOKE_00008	9.36e-42	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MCLBJOKE_00009	2.71e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MCLBJOKE_00010	4.85e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MCLBJOKE_00011	3.4e-145	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
MCLBJOKE_00012	8.81e-317	yagE	-	-	E	-	-	-	amino acid
MCLBJOKE_00013	6.91e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MCLBJOKE_00014	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MCLBJOKE_00015	2.13e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MCLBJOKE_00016	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MCLBJOKE_00017	2.94e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MCLBJOKE_00018	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MCLBJOKE_00019	5.16e-182	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MCLBJOKE_00020	4.21e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCLBJOKE_00021	3.4e-294	-	-	-	-	-	-	-	-
MCLBJOKE_00022	5.29e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MCLBJOKE_00023	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MCLBJOKE_00024	5.1e-97	-	-	-	F	-	-	-	Nudix hydrolase
MCLBJOKE_00025	1.11e-127	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
MCLBJOKE_00026	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MCLBJOKE_00027	6.63e-33	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
MCLBJOKE_00028	3.82e-192	-	-	-	-	-	-	-	-
MCLBJOKE_00029	2.91e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MCLBJOKE_00030	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
MCLBJOKE_00031	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
MCLBJOKE_00032	1.05e-228	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCLBJOKE_00033	6.08e-13	-	-	-	S	-	-	-	CsbD-like
MCLBJOKE_00034	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
MCLBJOKE_00035	1.24e-298	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MCLBJOKE_00036	4.71e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MCLBJOKE_00037	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MCLBJOKE_00038	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MCLBJOKE_00039	2.69e-311	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MCLBJOKE_00040	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MCLBJOKE_00041	2.62e-204	-	-	-	EG	-	-	-	EamA-like transporter family
MCLBJOKE_00042	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MCLBJOKE_00043	5.86e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MCLBJOKE_00044	2.25e-284	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MCLBJOKE_00046	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MCLBJOKE_00048	8.77e-200	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
MCLBJOKE_00049	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
MCLBJOKE_00050	1.51e-281	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MCLBJOKE_00051	1.11e-201	-	-	-	J	-	-	-	Methyltransferase
MCLBJOKE_00052	2.33e-49	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
MCLBJOKE_00054	3.65e-54	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MCLBJOKE_00055	1.09e-128	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain
MCLBJOKE_00056	6.78e-164	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
MCLBJOKE_00057	4.16e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MCLBJOKE_00058	1.18e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MCLBJOKE_00059	5.59e-120	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MCLBJOKE_00060	3.26e-57	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00061	1.01e-79	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00062	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
MCLBJOKE_00067	6.57e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00068	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
MCLBJOKE_00069	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MCLBJOKE_00070	1.52e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MCLBJOKE_00071	3.92e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MCLBJOKE_00072	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MCLBJOKE_00073	2.92e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MCLBJOKE_00074	6.2e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MCLBJOKE_00075	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MCLBJOKE_00076	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MCLBJOKE_00077	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MCLBJOKE_00078	5.34e-134	-	-	-	-	-	-	-	-
MCLBJOKE_00079	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MCLBJOKE_00080	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MCLBJOKE_00081	4.68e-187	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
MCLBJOKE_00082	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MCLBJOKE_00083	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MCLBJOKE_00084	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MCLBJOKE_00085	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MCLBJOKE_00086	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCLBJOKE_00087	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MCLBJOKE_00088	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MCLBJOKE_00090	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MCLBJOKE_00091	1.67e-307	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
MCLBJOKE_00092	1.83e-21	-	-	-	-	-	-	-	-
MCLBJOKE_00094	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MCLBJOKE_00095	1.41e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MCLBJOKE_00096	3.42e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MCLBJOKE_00097	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MCLBJOKE_00098	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MCLBJOKE_00099	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MCLBJOKE_00100	1.03e-19	-	-	-	-	-	-	-	-
MCLBJOKE_00101	1.02e-149	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MCLBJOKE_00102	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MCLBJOKE_00103	9.54e-113	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
MCLBJOKE_00104	2.43e-207	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
MCLBJOKE_00105	1.31e-268	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MCLBJOKE_00106	3.37e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MCLBJOKE_00107	3.09e-212	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
MCLBJOKE_00108	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
MCLBJOKE_00109	4.83e-173	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
MCLBJOKE_00110	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MCLBJOKE_00111	4.67e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MCLBJOKE_00112	2.72e-199	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MCLBJOKE_00113	2.29e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MCLBJOKE_00114	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MCLBJOKE_00115	1.49e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MCLBJOKE_00116	2.73e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MCLBJOKE_00117	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCLBJOKE_00118	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MCLBJOKE_00119	1.98e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MCLBJOKE_00120	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MCLBJOKE_00121	1.05e-183	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
MCLBJOKE_00122	1.63e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MCLBJOKE_00123	7.36e-57	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00124	1.01e-79	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00125	1.76e-99	usp5	-	-	T	-	-	-	universal stress protein
MCLBJOKE_00126	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
MCLBJOKE_00127	1.24e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MCLBJOKE_00128	3.79e-135	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
MCLBJOKE_00129	6.6e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MCLBJOKE_00130	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MCLBJOKE_00131	1.03e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MCLBJOKE_00132	1.05e-224	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MCLBJOKE_00133	7.76e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MCLBJOKE_00134	5.33e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MCLBJOKE_00135	1.21e-48	-	-	-	-	-	-	-	-
MCLBJOKE_00136	1.76e-68	-	-	-	-	-	-	-	-
MCLBJOKE_00137	1.11e-261	-	-	-	-	-	-	-	-
MCLBJOKE_00138	2.74e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCLBJOKE_00139	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MCLBJOKE_00140	4.18e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
MCLBJOKE_00141	4.33e-161	XK27_10500	-	-	K	-	-	-	response regulator
MCLBJOKE_00142	1.39e-229	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
MCLBJOKE_00143	5.84e-173	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00144	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MCLBJOKE_00145	1.45e-194	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MCLBJOKE_00146	1.03e-210	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MCLBJOKE_00147	1.38e-67	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MCLBJOKE_00148	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCLBJOKE_00149	6.16e-247	-	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_00150	5.77e-111	ymdB	-	-	S	-	-	-	Macro domain protein
MCLBJOKE_00151	1.01e-140	-	-	-	K	-	-	-	Helix-turn-helix domain
MCLBJOKE_00152	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MCLBJOKE_00153	2.1e-64	-	-	-	-	-	-	-	-
MCLBJOKE_00154	3.55e-296	-	-	-	S	-	-	-	Putative metallopeptidase domain
MCLBJOKE_00155	1.85e-264	-	-	-	S	-	-	-	associated with various cellular activities
MCLBJOKE_00156	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MCLBJOKE_00157	8.5e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MCLBJOKE_00159	6.52e-149	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
MCLBJOKE_00160	3.32e-72	-	-	-	-	-	-	-	-
MCLBJOKE_00162	1.94e-177	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MCLBJOKE_00163	2.04e-65	-	-	-	-	-	-	-	-
MCLBJOKE_00164	3.14e-254	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
MCLBJOKE_00165	6.33e-294	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MCLBJOKE_00166	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MCLBJOKE_00167	5.99e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
MCLBJOKE_00168	8.38e-186	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MCLBJOKE_00169	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MCLBJOKE_00172	3.53e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
MCLBJOKE_00174	6.62e-172	-	-	-	M	-	-	-	PFAM NLP P60 protein
MCLBJOKE_00175	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MCLBJOKE_00176	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MCLBJOKE_00177	9.34e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00178	3.1e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
MCLBJOKE_00179	2.79e-75	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MCLBJOKE_00180	1.3e-73	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MCLBJOKE_00181	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
MCLBJOKE_00182	1.13e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MCLBJOKE_00183	1.93e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MCLBJOKE_00184	9.49e-29	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCLBJOKE_00185	6.04e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MCLBJOKE_00186	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MCLBJOKE_00187	9.1e-184	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
MCLBJOKE_00188	1.15e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MCLBJOKE_00189	3.69e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MCLBJOKE_00190	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MCLBJOKE_00191	1.59e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
MCLBJOKE_00192	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MCLBJOKE_00194	2.3e-150	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MCLBJOKE_00195	2.27e-191	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MCLBJOKE_00196	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
MCLBJOKE_00197	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MCLBJOKE_00198	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MCLBJOKE_00199	4.73e-241	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MCLBJOKE_00200	1.14e-37	-	-	-	S	-	-	-	glycosyl transferase family 2
MCLBJOKE_00201	2.41e-50	-	-	-	S	-	-	-	glycosyl transferase family 2
MCLBJOKE_00202	1.25e-265	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
MCLBJOKE_00203	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MCLBJOKE_00204	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
MCLBJOKE_00205	4.93e-212	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
MCLBJOKE_00206	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MCLBJOKE_00207	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MCLBJOKE_00208	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MCLBJOKE_00210	0.0	-	-	-	M	-	-	-	family 8
MCLBJOKE_00211	0.0	-	-	-	M	-	-	-	family 8
MCLBJOKE_00215	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MCLBJOKE_00216	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MCLBJOKE_00217	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MCLBJOKE_00218	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MCLBJOKE_00219	1.84e-105	-	-	-	-	-	-	-	-
MCLBJOKE_00220	6.59e-48	-	-	-	-	-	-	-	-
MCLBJOKE_00221	8.23e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MCLBJOKE_00222	8.63e-165	-	-	-	-	-	-	-	-
MCLBJOKE_00223	1.37e-90	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MCLBJOKE_00224	4.07e-223	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MCLBJOKE_00225	1.43e-193	epsB	-	-	M	-	-	-	biosynthesis protein
MCLBJOKE_00226	5.26e-159	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MCLBJOKE_00227	2.46e-63	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
MCLBJOKE_00228	1.76e-105	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
MCLBJOKE_00229	1.33e-66	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MCLBJOKE_00230	1.83e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MCLBJOKE_00231	5.74e-155	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MCLBJOKE_00232	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MCLBJOKE_00233	1.1e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MCLBJOKE_00234	9.76e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
MCLBJOKE_00235	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MCLBJOKE_00236	1.02e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00237	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MCLBJOKE_00238	4.11e-292	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MCLBJOKE_00239	1.06e-314	ymfH	-	-	S	-	-	-	Peptidase M16
MCLBJOKE_00240	2.78e-194	-	-	-	S	-	-	-	Helix-turn-helix domain
MCLBJOKE_00241	2.35e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MCLBJOKE_00242	1.95e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MCLBJOKE_00243	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MCLBJOKE_00244	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MCLBJOKE_00245	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MCLBJOKE_00246	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MCLBJOKE_00247	2.15e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MCLBJOKE_00248	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MCLBJOKE_00249	2.05e-256	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MCLBJOKE_00250	6.17e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MCLBJOKE_00251	2.06e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MCLBJOKE_00252	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MCLBJOKE_00253	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MCLBJOKE_00254	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MCLBJOKE_00255	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MCLBJOKE_00256	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MCLBJOKE_00257	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
MCLBJOKE_00258	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MCLBJOKE_00259	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MCLBJOKE_00260	8.27e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MCLBJOKE_00261	2.21e-185	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MCLBJOKE_00262	4.93e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MCLBJOKE_00263	1.51e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MCLBJOKE_00264	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
MCLBJOKE_00265	1.91e-196	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MCLBJOKE_00266	2.65e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MCLBJOKE_00267	1.04e-69	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MCLBJOKE_00268	3.65e-47	-	-	-	-	-	-	-	-
MCLBJOKE_00269	2.18e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MCLBJOKE_00270	2.41e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MCLBJOKE_00271	2.32e-178	-	-	-	-	-	-	-	-
MCLBJOKE_00272	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MCLBJOKE_00273	1.7e-234	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MCLBJOKE_00274	1.75e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MCLBJOKE_00275	1.49e-60	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MCLBJOKE_00276	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
MCLBJOKE_00277	2.78e-55	-	-	-	-	-	-	-	-
MCLBJOKE_00278	7.66e-91	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
MCLBJOKE_00279	1.46e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MCLBJOKE_00280	5.54e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCLBJOKE_00281	3.48e-152	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MCLBJOKE_00282	4.3e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MCLBJOKE_00283	5.87e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MCLBJOKE_00284	9.74e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MCLBJOKE_00285	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MCLBJOKE_00286	7.05e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MCLBJOKE_00287	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MCLBJOKE_00288	1.21e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MCLBJOKE_00289	1.1e-312	-	-	-	M	-	-	-	Glycosyl transferase family group 2
MCLBJOKE_00291	1.03e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
MCLBJOKE_00293	2.38e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MCLBJOKE_00294	8.03e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MCLBJOKE_00295	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MCLBJOKE_00296	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MCLBJOKE_00297	2.59e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCLBJOKE_00298	2.52e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MCLBJOKE_00299	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MCLBJOKE_00300	5.99e-266	yacL	-	-	S	-	-	-	domain protein
MCLBJOKE_00301	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MCLBJOKE_00302	3.42e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MCLBJOKE_00303	1.93e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MCLBJOKE_00304	7.17e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MCLBJOKE_00305	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MCLBJOKE_00306	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MCLBJOKE_00307	3.52e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00308	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCLBJOKE_00309	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MCLBJOKE_00310	1.54e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MCLBJOKE_00311	1.76e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MCLBJOKE_00312	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MCLBJOKE_00313	8.74e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MCLBJOKE_00314	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MCLBJOKE_00316	1.93e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MCLBJOKE_00317	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
MCLBJOKE_00318	1.58e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MCLBJOKE_00319	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MCLBJOKE_00320	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
MCLBJOKE_00321	1.28e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MCLBJOKE_00322	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
MCLBJOKE_00323	0.0	-	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_00324	3.98e-146	-	-	-	-	-	-	-	-
MCLBJOKE_00327	1.95e-64	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MCLBJOKE_00328	1.32e-112	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MCLBJOKE_00329	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MCLBJOKE_00332	2.63e-214	-	-	-	C	-	-	-	Oxidoreductase
MCLBJOKE_00333	1.61e-81	-	-	-	S	-	-	-	macrophage migration inhibitory factor
MCLBJOKE_00334	3.48e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MCLBJOKE_00335	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MCLBJOKE_00336	3.96e-76	-	-	-	-	-	-	-	-
MCLBJOKE_00337	2.54e-286	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MCLBJOKE_00338	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MCLBJOKE_00339	3.32e-240	-	-	-	S	-	-	-	Helix-turn-helix domain
MCLBJOKE_00340	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MCLBJOKE_00341	1.37e-69	-	-	-	M	-	-	-	Lysin motif
MCLBJOKE_00342	1.66e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MCLBJOKE_00343	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MCLBJOKE_00344	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MCLBJOKE_00345	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MCLBJOKE_00346	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MCLBJOKE_00347	1.65e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MCLBJOKE_00348	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00349	2.44e-245	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MCLBJOKE_00350	1.88e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MCLBJOKE_00351	4.3e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MCLBJOKE_00352	2.6e-195	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
MCLBJOKE_00353	1.32e-218	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MCLBJOKE_00354	2.85e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
MCLBJOKE_00355	7.68e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MCLBJOKE_00356	5.1e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MCLBJOKE_00357	5.03e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCLBJOKE_00358	7.52e-205	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MCLBJOKE_00359	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MCLBJOKE_00360	1.17e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MCLBJOKE_00361	1.56e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MCLBJOKE_00362	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCLBJOKE_00363	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MCLBJOKE_00364	2.32e-109	-	-	-	F	-	-	-	NUDIX domain
MCLBJOKE_00365	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MCLBJOKE_00366	3.67e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MCLBJOKE_00367	5.29e-65	-	-	-	-	-	-	-	-
MCLBJOKE_00369	1.32e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MCLBJOKE_00370	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MCLBJOKE_00371	3.09e-35	-	-	-	-	-	-	-	-
MCLBJOKE_00372	3.97e-125	-	-	-	-	-	-	-	-
MCLBJOKE_00373	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MCLBJOKE_00374	4.12e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
MCLBJOKE_00375	2.69e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
MCLBJOKE_00376	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MCLBJOKE_00377	3.42e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MCLBJOKE_00378	7.67e-63	-	-	-	-	-	-	-	-
MCLBJOKE_00379	2.58e-41	-	-	-	-	-	-	-	-
MCLBJOKE_00380	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
MCLBJOKE_00381	5.13e-60	-	-	-	-	-	-	-	-
MCLBJOKE_00382	8.49e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
MCLBJOKE_00384	2.2e-19	-	-	-	IQ	-	-	-	KR domain
MCLBJOKE_00385	1.19e-311	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
MCLBJOKE_00386	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MCLBJOKE_00387	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MCLBJOKE_00388	1.52e-141	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
MCLBJOKE_00389	2.73e-148	-	-	-	M	-	-	-	LysM domain protein
MCLBJOKE_00390	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
MCLBJOKE_00391	3.93e-138	-	-	-	M	-	-	-	LysM domain protein
MCLBJOKE_00392	2.83e-190	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MCLBJOKE_00393	1.09e-143	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MCLBJOKE_00394	5.26e-188	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MCLBJOKE_00395	8.69e-195	yeaE	-	-	S	-	-	-	Aldo keto
MCLBJOKE_00396	1.89e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MCLBJOKE_00397	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
MCLBJOKE_00398	4.58e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MCLBJOKE_00399	4.13e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MCLBJOKE_00400	7.03e-33	-	-	-	-	-	-	-	-
MCLBJOKE_00401	8.28e-135	-	-	-	V	-	-	-	VanZ like family
MCLBJOKE_00402	6.7e-301	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MCLBJOKE_00403	2.08e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MCLBJOKE_00404	0.0	-	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_00405	7.72e-122	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MCLBJOKE_00406	1.34e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MCLBJOKE_00407	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MCLBJOKE_00408	8.74e-57	-	-	-	-	-	-	-	-
MCLBJOKE_00409	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MCLBJOKE_00410	1.37e-45	-	-	-	-	-	-	-	-
MCLBJOKE_00411	4.78e-35	-	-	-	-	-	-	-	-
MCLBJOKE_00413	4.7e-25	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MCLBJOKE_00414	2.14e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MCLBJOKE_00415	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MCLBJOKE_00416	1.08e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MCLBJOKE_00417	4.51e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MCLBJOKE_00418	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MCLBJOKE_00419	1.26e-145	-	-	-	-	-	-	-	-
MCLBJOKE_00420	3.58e-238	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
MCLBJOKE_00421	8.09e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MCLBJOKE_00422	1.52e-43	-	-	-	-	-	-	-	-
MCLBJOKE_00423	1.43e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MCLBJOKE_00424	9.17e-59	-	-	-	-	-	-	-	-
MCLBJOKE_00426	5.18e-72	-	-	-	-	-	-	-	-
MCLBJOKE_00427	2.13e-185	-	-	-	S	-	-	-	Domain of unknown function DUF1829
MCLBJOKE_00428	8.27e-96	-	-	-	-	-	-	-	-
MCLBJOKE_00429	1.22e-74	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MCLBJOKE_00430	5.53e-122	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MCLBJOKE_00431	7.92e-135	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MCLBJOKE_00432	1.51e-280	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MCLBJOKE_00433	8.24e-133	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MCLBJOKE_00434	2.03e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MCLBJOKE_00435	1.32e-60	-	-	-	-	-	-	-	-
MCLBJOKE_00436	1.49e-54	-	-	-	-	-	-	-	-
MCLBJOKE_00438	1.67e-99	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MCLBJOKE_00439	7.66e-66	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MCLBJOKE_00440	1.36e-126	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MCLBJOKE_00441	4.43e-254	-	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_00442	4.49e-162	-	-	-	M	-	-	-	Lysin motif
MCLBJOKE_00443	5.69e-105	-	-	-	-	-	-	-	-
MCLBJOKE_00444	9.66e-79	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MCLBJOKE_00445	1.44e-99	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MCLBJOKE_00446	1.25e-124	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
MCLBJOKE_00447	2.96e-265	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MCLBJOKE_00448	3.7e-19	-	-	-	-	-	-	-	-
MCLBJOKE_00449	1.25e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MCLBJOKE_00450	9.33e-252	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MCLBJOKE_00451	2.53e-146	-	-	-	S	-	-	-	Membrane
MCLBJOKE_00452	5.86e-157	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
MCLBJOKE_00453	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MCLBJOKE_00454	6.43e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MCLBJOKE_00456	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MCLBJOKE_00457	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MCLBJOKE_00458	9.36e-42	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MCLBJOKE_00459	2.91e-65	-	-	-	-	-	-	-	-
MCLBJOKE_00461	4.01e-63	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MCLBJOKE_00462	9.71e-76	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
MCLBJOKE_00463	1.39e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
MCLBJOKE_00464	3.67e-176	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MCLBJOKE_00465	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MCLBJOKE_00466	3.81e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCLBJOKE_00467	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MCLBJOKE_00468	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MCLBJOKE_00469	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MCLBJOKE_00470	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCLBJOKE_00471	6.86e-61	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MCLBJOKE_00472	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MCLBJOKE_00473	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MCLBJOKE_00474	5.48e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MCLBJOKE_00475	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MCLBJOKE_00476	3.7e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MCLBJOKE_00477	1.07e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MCLBJOKE_00478	3.17e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MCLBJOKE_00479	2.58e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MCLBJOKE_00480	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MCLBJOKE_00481	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MCLBJOKE_00482	6.8e-224	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MCLBJOKE_00483	7.32e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MCLBJOKE_00484	7.34e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MCLBJOKE_00485	4.12e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MCLBJOKE_00486	5.83e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MCLBJOKE_00487	1.26e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCLBJOKE_00488	2.35e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MCLBJOKE_00489	3.64e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MCLBJOKE_00490	3.01e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MCLBJOKE_00491	4.39e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MCLBJOKE_00492	2.41e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MCLBJOKE_00493	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MCLBJOKE_00494	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MCLBJOKE_00496	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MCLBJOKE_00497	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MCLBJOKE_00498	4.31e-43	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
MCLBJOKE_00499	7.42e-44	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MCLBJOKE_00500	0.0	-	-	-	E	-	-	-	amino acid
MCLBJOKE_00501	0.0	ydaO	-	-	E	-	-	-	amino acid
MCLBJOKE_00502	1.78e-51	-	-	-	-	-	-	-	-
MCLBJOKE_00503	9.12e-67	-	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_00504	6.25e-196	-	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_00505	9.46e-49	-	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_00506	1.33e-66	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MCLBJOKE_00507	1.98e-257	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MCLBJOKE_00509	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MCLBJOKE_00510	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MCLBJOKE_00511	1.09e-103	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MCLBJOKE_00512	9.67e-107	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MCLBJOKE_00513	5.94e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MCLBJOKE_00514	2.24e-193	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MCLBJOKE_00515	4.98e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MCLBJOKE_00516	2.62e-281	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MCLBJOKE_00517	2.33e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MCLBJOKE_00518	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MCLBJOKE_00519	8.18e-49	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MCLBJOKE_00520	6.01e-263	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MCLBJOKE_00521	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MCLBJOKE_00522	3.26e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MCLBJOKE_00523	1.15e-24	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MCLBJOKE_00524	5.62e-75	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MCLBJOKE_00533	1.85e-109	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
MCLBJOKE_00534	2.14e-71	-	-	-	-	-	-	-	-
MCLBJOKE_00535	2.91e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MCLBJOKE_00536	4.87e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MCLBJOKE_00538	2.17e-61	yrvD	-	-	S	-	-	-	Pfam:DUF1049
MCLBJOKE_00539	5.24e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MCLBJOKE_00540	3.96e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MCLBJOKE_00541	1.75e-29	-	-	-	-	-	-	-	-
MCLBJOKE_00542	1.23e-50	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MCLBJOKE_00543	1.24e-115	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MCLBJOKE_00544	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MCLBJOKE_00545	6.49e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MCLBJOKE_00546	4.12e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
MCLBJOKE_00547	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCLBJOKE_00548	6.94e-202	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MCLBJOKE_00549	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MCLBJOKE_00551	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MCLBJOKE_00552	1.09e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MCLBJOKE_00553	4.81e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
MCLBJOKE_00554	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MCLBJOKE_00555	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MCLBJOKE_00556	6.69e-175	-	-	-	S	-	-	-	DUF218 domain
MCLBJOKE_00557	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
MCLBJOKE_00558	2.75e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
MCLBJOKE_00559	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
MCLBJOKE_00560	5.01e-310	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MCLBJOKE_00561	2.61e-95	-	-	-	S	-	-	-	UPF0756 membrane protein
MCLBJOKE_00562	9.73e-100	-	-	-	S	-	-	-	Cupin domain
MCLBJOKE_00563	5.68e-83	-	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_00564	3.32e-194	yvgN	-	-	C	-	-	-	Aldo keto reductase
MCLBJOKE_00565	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MCLBJOKE_00566	5.27e-102	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MCLBJOKE_00567	1.75e-189	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MCLBJOKE_00568	4.52e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MCLBJOKE_00570	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
MCLBJOKE_00571	2.38e-68	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
MCLBJOKE_00573	7.98e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MCLBJOKE_00574	6.7e-205	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
MCLBJOKE_00575	1.03e-121	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MCLBJOKE_00576	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MCLBJOKE_00577	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MCLBJOKE_00578	4e-76	-	-	-	-	-	-	-	-
MCLBJOKE_00579	8.67e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MCLBJOKE_00580	2.29e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MCLBJOKE_00581	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MCLBJOKE_00582	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MCLBJOKE_00583	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MCLBJOKE_00584	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MCLBJOKE_00585	3.99e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MCLBJOKE_00586	2.35e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MCLBJOKE_00587	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MCLBJOKE_00588	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MCLBJOKE_00589	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MCLBJOKE_00590	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MCLBJOKE_00591	2.92e-187	ylmH	-	-	S	-	-	-	S4 domain protein
MCLBJOKE_00592	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MCLBJOKE_00593	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MCLBJOKE_00594	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MCLBJOKE_00595	1.44e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MCLBJOKE_00596	1.54e-33	-	-	-	-	-	-	-	-
MCLBJOKE_00597	8.02e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MCLBJOKE_00598	9.04e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MCLBJOKE_00599	2.27e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MCLBJOKE_00600	1.02e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MCLBJOKE_00601	4.69e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
MCLBJOKE_00602	3.82e-157	-	-	-	S	-	-	-	repeat protein
MCLBJOKE_00603	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MCLBJOKE_00604	4.96e-222	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCLBJOKE_00605	1.78e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MCLBJOKE_00606	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MCLBJOKE_00607	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MCLBJOKE_00608	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MCLBJOKE_00609	2.6e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MCLBJOKE_00610	1.88e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MCLBJOKE_00611	4.65e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MCLBJOKE_00612	9.79e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MCLBJOKE_00613	4.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MCLBJOKE_00614	1.03e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MCLBJOKE_00615	3.71e-76	-	-	-	-	-	-	-	-
MCLBJOKE_00617	2.51e-239	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MCLBJOKE_00618	4.37e-39	-	-	-	-	-	-	-	-
MCLBJOKE_00619	3.55e-231	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
MCLBJOKE_00620	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MCLBJOKE_00621	2.79e-107	-	-	-	-	-	-	-	-
MCLBJOKE_00622	6.83e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MCLBJOKE_00623	4.05e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MCLBJOKE_00624	3.28e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
MCLBJOKE_00625	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MCLBJOKE_00626	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
MCLBJOKE_00627	1.66e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MCLBJOKE_00628	9.67e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
MCLBJOKE_00629	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MCLBJOKE_00630	7.88e-286	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MCLBJOKE_00631	5.25e-59	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MCLBJOKE_00632	2.37e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MCLBJOKE_00633	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MCLBJOKE_00634	3.14e-254	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MCLBJOKE_00635	6.57e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MCLBJOKE_00636	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MCLBJOKE_00637	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MCLBJOKE_00638	1.32e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MCLBJOKE_00639	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MCLBJOKE_00640	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MCLBJOKE_00641	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCLBJOKE_00642	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
MCLBJOKE_00643	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MCLBJOKE_00644	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MCLBJOKE_00645	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MCLBJOKE_00646	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MCLBJOKE_00647	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
MCLBJOKE_00648	2.44e-20	-	-	-	-	-	-	-	-
MCLBJOKE_00649	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MCLBJOKE_00650	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MCLBJOKE_00651	1.38e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MCLBJOKE_00652	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MCLBJOKE_00653	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MCLBJOKE_00654	1.77e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MCLBJOKE_00655	1.53e-122	-	-	-	-	-	-	-	-
MCLBJOKE_00656	3.5e-195	-	-	-	M	-	-	-	MucBP domain
MCLBJOKE_00658	3.31e-20	-	-	-	-	-	-	-	-
MCLBJOKE_00659	1.83e-19	-	-	-	-	-	-	-	-
MCLBJOKE_00662	1.1e-158	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MCLBJOKE_00663	3.35e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MCLBJOKE_00664	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MCLBJOKE_00665	2.22e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
MCLBJOKE_00666	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MCLBJOKE_00667	3.72e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MCLBJOKE_00668	5.67e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MCLBJOKE_00669	3.79e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
MCLBJOKE_00670	1.69e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCLBJOKE_00671	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MCLBJOKE_00672	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MCLBJOKE_00673	1.81e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MCLBJOKE_00674	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MCLBJOKE_00675	7.14e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MCLBJOKE_00676	8.28e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MCLBJOKE_00677	8.1e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MCLBJOKE_00678	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MCLBJOKE_00679	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MCLBJOKE_00680	5.44e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MCLBJOKE_00681	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MCLBJOKE_00682	1.2e-59	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MCLBJOKE_00683	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
MCLBJOKE_00684	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MCLBJOKE_00685	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MCLBJOKE_00686	1.16e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MCLBJOKE_00687	3.65e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MCLBJOKE_00688	1.26e-84	-	-	-	-	-	-	-	-
MCLBJOKE_00689	4.58e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MCLBJOKE_00690	4.68e-117	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MCLBJOKE_00691	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MCLBJOKE_00692	1.09e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MCLBJOKE_00693	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MCLBJOKE_00694	6.35e-177	-	-	-	IQ	-	-	-	KR domain
MCLBJOKE_00695	1.6e-169	-	-	-	M	-	-	-	Rib/alpha-like repeat
MCLBJOKE_00696	0.000617	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MCLBJOKE_00697	5.49e-167	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MCLBJOKE_00698	2.61e-282	potE	-	-	E	-	-	-	Amino Acid
MCLBJOKE_00699	2.88e-125	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MCLBJOKE_00700	8.83e-303	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00701	6.57e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MCLBJOKE_00702	6.5e-71	-	-	-	-	-	-	-	-
MCLBJOKE_00703	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MCLBJOKE_00704	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MCLBJOKE_00705	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MCLBJOKE_00706	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_00707	8.16e-206	-	-	-	-	-	-	-	-
MCLBJOKE_00708	1.06e-19	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MCLBJOKE_00709	7.42e-95	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MCLBJOKE_00710	3.81e-48	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MCLBJOKE_00711	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MCLBJOKE_00712	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_00713	7.9e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MCLBJOKE_00714	2.01e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MCLBJOKE_00715	2.31e-11	-	-	-	-	-	-	-	-
MCLBJOKE_00716	1.78e-83	-	-	-	-	-	-	-	-
MCLBJOKE_00717	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MCLBJOKE_00718	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
MCLBJOKE_00719	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MCLBJOKE_00720	2.65e-214	-	-	-	GK	-	-	-	ROK family
MCLBJOKE_00721	2.79e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MCLBJOKE_00722	1.02e-176	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MCLBJOKE_00723	7.11e-309	-	-	-	E	-	-	-	amino acid
MCLBJOKE_00724	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MCLBJOKE_00725	7.12e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MCLBJOKE_00726	1.16e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MCLBJOKE_00727	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MCLBJOKE_00728	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MCLBJOKE_00729	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00730	4.73e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCLBJOKE_00731	2.49e-80	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00732	7.98e-18	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_00733	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MCLBJOKE_00734	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MCLBJOKE_00735	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MCLBJOKE_00736	3.09e-62	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
MCLBJOKE_00737	5.16e-215	-	-	-	C	-	-	-	Aldo keto reductase
MCLBJOKE_00738	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MCLBJOKE_00739	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MCLBJOKE_00740	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MCLBJOKE_00741	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MCLBJOKE_00742	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MCLBJOKE_00743	1.45e-262	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MCLBJOKE_00744	1.17e-220	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MCLBJOKE_00745	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MCLBJOKE_00746	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MCLBJOKE_00747	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MCLBJOKE_00748	2.02e-138	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
MCLBJOKE_00750	1.03e-208	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MCLBJOKE_00751	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
MCLBJOKE_00752	8.68e-44	-	-	-	-	-	-	-	-
MCLBJOKE_00753	1.04e-268	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MCLBJOKE_00754	1.54e-224	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MCLBJOKE_00755	2.39e-98	-	-	-	O	-	-	-	OsmC-like protein
MCLBJOKE_00757	5.67e-309	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MCLBJOKE_00759	9.01e-179	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MCLBJOKE_00760	1.85e-301	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MCLBJOKE_00761	5.97e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MCLBJOKE_00763	1.11e-192	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MCLBJOKE_00764	2.6e-96	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MCLBJOKE_00765	5.89e-71	-	-	-	S	-	-	-	Bacteriophage holin family
MCLBJOKE_00768	6.62e-49	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MCLBJOKE_00771	0.0	-	-	-	M	-	-	-	CHAP domain
MCLBJOKE_00772	4.86e-214	-	-	-	S	-	-	-	Phage tail protein
MCLBJOKE_00773	1.08e-226	-	-	-	D	-	-	-	domain protein
MCLBJOKE_00774	6.07e-120	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
MCLBJOKE_00775	5.93e-155	-	-	-	-	-	-	-	-
MCLBJOKE_00776	1.35e-92	-	-	-	-	-	-	-	-
MCLBJOKE_00777	1.65e-115	-	-	-	-	-	-	-	-
MCLBJOKE_00778	2.28e-60	-	-	-	-	-	-	-	-
MCLBJOKE_00779	8.26e-80	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MCLBJOKE_00780	1.32e-250	gpG	-	-	-	-	-	-	-
MCLBJOKE_00781	8.07e-129	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MCLBJOKE_00783	1.85e-213	-	-	-	S	-	-	-	Phage Mu protein F like protein
MCLBJOKE_00784	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MCLBJOKE_00785	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
MCLBJOKE_00787	6.49e-154	-	-	-	K	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MCLBJOKE_00789	2.58e-88	-	-	-	-	-	-	-	-
MCLBJOKE_00790	1.76e-155	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	sulfate reduction
MCLBJOKE_00791	7.73e-109	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MCLBJOKE_00794	9.96e-23	-	-	-	-	-	-	-	-
MCLBJOKE_00797	2.75e-21	-	-	-	-	-	-	-	-
MCLBJOKE_00798	5.51e-106	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
MCLBJOKE_00800	1.72e-67	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
MCLBJOKE_00801	8.24e-22	-	-	-	-	-	-	-	-
MCLBJOKE_00806	5.21e-47	-	-	-	L	-	-	-	DnaD domain protein
MCLBJOKE_00807	2.16e-191	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
MCLBJOKE_00808	5.46e-207	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MCLBJOKE_00816	1.88e-11	-	-	-	-	-	-	-	-
MCLBJOKE_00817	9e-66	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MCLBJOKE_00823	4.41e-65	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MCLBJOKE_00824	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MCLBJOKE_00825	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MCLBJOKE_00826	1.05e-272	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MCLBJOKE_00827	0.0	yhaN	-	-	L	-	-	-	AAA domain
MCLBJOKE_00828	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MCLBJOKE_00830	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
MCLBJOKE_00831	3.28e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_00832	1.1e-277	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MCLBJOKE_00833	2.52e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MCLBJOKE_00834	8.85e-51	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
MCLBJOKE_00835	2.06e-124	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
MCLBJOKE_00836	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MCLBJOKE_00837	7.11e-228	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MCLBJOKE_00838	6.99e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MCLBJOKE_00839	5.16e-72	-	-	-	S	-	-	-	Small secreted protein
MCLBJOKE_00840	2.42e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
MCLBJOKE_00841	2.23e-150	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCLBJOKE_00842	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MCLBJOKE_00843	7.56e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MCLBJOKE_00844	2.05e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MCLBJOKE_00845	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MCLBJOKE_00846	7.23e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MCLBJOKE_00847	4.46e-124	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MCLBJOKE_00848	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MCLBJOKE_00849	7.28e-303	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
MCLBJOKE_00850	2.46e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MCLBJOKE_00851	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MCLBJOKE_00852	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MCLBJOKE_00853	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MCLBJOKE_00854	1.83e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MCLBJOKE_00855	7.41e-277	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MCLBJOKE_00856	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
MCLBJOKE_00857	4.03e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MCLBJOKE_00858	4.2e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MCLBJOKE_00859	1.56e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MCLBJOKE_00860	6.38e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
MCLBJOKE_00861	5.61e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MCLBJOKE_00862	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MCLBJOKE_00863	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MCLBJOKE_00864	6.68e-156	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
MCLBJOKE_00865	2.32e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
MCLBJOKE_00866	3.32e-74	-	-	-	E	ko:K04031	-	ko00000	BMC
MCLBJOKE_00867	7.5e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MCLBJOKE_00868	6.52e-270	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
MCLBJOKE_00869	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
MCLBJOKE_00870	1.01e-104	pduO	-	-	S	-	-	-	Haem-degrading
MCLBJOKE_00871	1.26e-137	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
MCLBJOKE_00872	1.96e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
MCLBJOKE_00873	2.75e-116	-	-	-	S	-	-	-	Putative propanediol utilisation
MCLBJOKE_00874	1.77e-151	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
MCLBJOKE_00875	2.38e-56	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
MCLBJOKE_00876	3.28e-112	-	-	-	CQ	-	-	-	BMC
MCLBJOKE_00877	4.82e-78	pduH	-	-	S	-	-	-	Dehydratase medium subunit
MCLBJOKE_00878	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
MCLBJOKE_00879	1.1e-106	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
MCLBJOKE_00880	6.34e-165	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
MCLBJOKE_00881	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
MCLBJOKE_00882	3.41e-170	pduB	-	-	E	-	-	-	BMC
MCLBJOKE_00883	2.72e-56	-	-	-	CQ	-	-	-	BMC
MCLBJOKE_00884	1.05e-252	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MCLBJOKE_00885	2.21e-190	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
MCLBJOKE_00886	1.19e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MCLBJOKE_00887	1.78e-209	-	-	-	-	-	-	-	-
MCLBJOKE_00888	6.42e-201	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MCLBJOKE_00889	1.61e-237	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
MCLBJOKE_00890	6.1e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
MCLBJOKE_00891	1.93e-101	yybA	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_00892	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MCLBJOKE_00893	4e-117	-	-	-	GM	-	-	-	epimerase
MCLBJOKE_00894	1.63e-197	-	-	-	V	-	-	-	(ABC) transporter
MCLBJOKE_00895	4.1e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
MCLBJOKE_00896	4e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MCLBJOKE_00897	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
MCLBJOKE_00898	3.59e-244	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
MCLBJOKE_00899	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MCLBJOKE_00900	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MCLBJOKE_00901	1.8e-45	-	-	-	-	-	-	-	-
MCLBJOKE_00902	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MCLBJOKE_00904	1.86e-241	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MCLBJOKE_00905	3.75e-77	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
MCLBJOKE_00906	6.51e-46	-	-	-	-	-	-	-	-
MCLBJOKE_00910	3.53e-206	-	-	-	-	-	-	-	-
MCLBJOKE_00914	3.18e-19	-	-	-	LM	-	-	-	gp58-like protein
MCLBJOKE_00915	2.68e-267	-	-	-	M	-	-	-	Prophage endopeptidase tail
MCLBJOKE_00916	3.96e-150	-	-	-	S	-	-	-	Phage tail protein
MCLBJOKE_00917	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MCLBJOKE_00919	7.5e-84	-	-	-	S	-	-	-	Phage tail tube protein
MCLBJOKE_00920	2.83e-26	-	-	-	-	-	-	-	-
MCLBJOKE_00921	5.56e-27	-	-	-	-	-	-	-	-
MCLBJOKE_00922	3.56e-50	-	-	-	S	-	-	-	Phage head-tail joining protein
MCLBJOKE_00923	4.01e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MCLBJOKE_00924	3.03e-165	-	-	-	S	-	-	-	Phage capsid family
MCLBJOKE_00925	7.29e-113	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MCLBJOKE_00926	1.99e-181	-	-	-	S	-	-	-	portal protein
MCLBJOKE_00928	0.0	-	-	-	S	-	-	-	Phage Terminase
MCLBJOKE_00929	1.99e-104	-	-	-	L	-	-	-	Phage terminase, small subunit
MCLBJOKE_00930	3.97e-66	-	-	-	L	-	-	-	HNH nucleases
MCLBJOKE_00943	5.57e-75	-	-	-	K	-	-	-	Virulence activator alpha C-term
MCLBJOKE_00944	6.71e-220	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MCLBJOKE_00945	8.09e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MCLBJOKE_00946	4.13e-197	-	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_00947	2.6e-201	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MCLBJOKE_00948	1.13e-81	-	-	-	-	-	-	-	-
MCLBJOKE_00949	1.7e-167	-	-	-	F	-	-	-	glutamine amidotransferase
MCLBJOKE_00951	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MCLBJOKE_00952	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MCLBJOKE_00953	9.51e-39	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MCLBJOKE_00954	9.85e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MCLBJOKE_00955	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MCLBJOKE_00956	2.06e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
MCLBJOKE_00957	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MCLBJOKE_00958	4.7e-263	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MCLBJOKE_00959	4.41e-289	-	-	-	-	-	-	-	-
MCLBJOKE_00960	4.04e-103	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MCLBJOKE_00961	2.16e-136	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MCLBJOKE_00962	1.85e-67	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MCLBJOKE_00963	2e-14	-	-	-	GM	-	-	-	NmrA-like family
MCLBJOKE_00964	4.78e-95	-	-	-	S	ko:K02348	-	ko00000	Gnat family
MCLBJOKE_00965	7.72e-51	-	-	-	S	-	-	-	Cytochrome B5
MCLBJOKE_00966	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
MCLBJOKE_00967	1.29e-53	-	-	-	S	-	-	-	Cytochrome B5
MCLBJOKE_00968	1.17e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MCLBJOKE_00970	4e-234	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MCLBJOKE_00971	1.72e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
MCLBJOKE_00972	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
MCLBJOKE_00973	2.62e-25	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MCLBJOKE_00974	6.56e-148	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MCLBJOKE_00975	5.72e-40	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MCLBJOKE_00977	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MCLBJOKE_00978	1.31e-75	-	-	-	-	-	-	-	-
MCLBJOKE_00979	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MCLBJOKE_00981	2.51e-199	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MCLBJOKE_00982	1.28e-18	-	-	-	-	-	-	-	-
MCLBJOKE_00983	5.1e-284	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MCLBJOKE_00984	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MCLBJOKE_00985	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MCLBJOKE_00986	6.56e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MCLBJOKE_00987	9.76e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MCLBJOKE_00988	2.81e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MCLBJOKE_00989	2.06e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MCLBJOKE_00990	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MCLBJOKE_00991	5.62e-146	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
MCLBJOKE_00992	1.55e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MCLBJOKE_00993	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MCLBJOKE_00994	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MCLBJOKE_00995	0.0	-	-	-	S	-	-	-	membrane
MCLBJOKE_00996	5.43e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MCLBJOKE_00997	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MCLBJOKE_00998	8.38e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MCLBJOKE_00999	1.98e-147	-	-	-	M	-	-	-	PFAM NLP P60 protein
MCLBJOKE_01000	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MCLBJOKE_01001	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MCLBJOKE_01002	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MCLBJOKE_01003	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MCLBJOKE_01004	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MCLBJOKE_01005	2.86e-57	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MCLBJOKE_01006	9.55e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCLBJOKE_01007	5.52e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MCLBJOKE_01008	1.28e-293	-	-	-	V	-	-	-	MatE
MCLBJOKE_01009	0.0	potE	-	-	E	-	-	-	Amino Acid
MCLBJOKE_01010	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCLBJOKE_01011	9.72e-156	csrR	-	-	K	-	-	-	response regulator
MCLBJOKE_01014	7.38e-48	-	-	-	S	-	-	-	Bacteriophage holin family
MCLBJOKE_01015	1.99e-75	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MCLBJOKE_01016	1.81e-253	-	-	-	M	-	-	-	hydrolase, family 25
MCLBJOKE_01017	2.73e-36	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
MCLBJOKE_01018	7.81e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MCLBJOKE_01019	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MCLBJOKE_01020	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MCLBJOKE_01021	5.36e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MCLBJOKE_01022	1.36e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MCLBJOKE_01023	2.49e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MCLBJOKE_01024	3.51e-180	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MCLBJOKE_01025	2.24e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MCLBJOKE_01026	7.4e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MCLBJOKE_01027	4.74e-86	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MCLBJOKE_01031	1.66e-99	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MCLBJOKE_01032	7.91e-63	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MCLBJOKE_01033	2.11e-28	-	-	-	-	-	-	-	-
MCLBJOKE_01034	5.34e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
MCLBJOKE_01042	3.96e-71	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MCLBJOKE_01043	9.11e-170	-	-	-	S	-	-	-	Putative HNHc nuclease
MCLBJOKE_01044	1.03e-46	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MCLBJOKE_01048	1.48e-48	-	-	-	-	-	-	-	-
MCLBJOKE_01049	1.49e-41	-	-	-	-	-	-	-	-
MCLBJOKE_01050	1.11e-95	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MCLBJOKE_01058	4.93e-208	-	-	-	-	-	-	-	-
MCLBJOKE_01059	2.64e-156	-	-	-	F	-	-	-	deoxynucleoside kinase
MCLBJOKE_01064	1.9e-99	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
MCLBJOKE_01066	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MCLBJOKE_01067	1.97e-280	arcT	-	-	E	-	-	-	Aminotransferase
MCLBJOKE_01068	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MCLBJOKE_01069	5.49e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MCLBJOKE_01070	4.94e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MCLBJOKE_01071	2.86e-72	-	-	-	-	-	-	-	-
MCLBJOKE_01072	4.21e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MCLBJOKE_01074	1.91e-297	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MCLBJOKE_01075	4.39e-244	mocA	-	-	S	-	-	-	Oxidoreductase
MCLBJOKE_01076	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
MCLBJOKE_01077	6.95e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MCLBJOKE_01078	3.74e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MCLBJOKE_01079	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MCLBJOKE_01080	1.64e-242	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
MCLBJOKE_01081	2.61e-95	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
MCLBJOKE_01082	5.33e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MCLBJOKE_01083	1.7e-26	-	-	-	-	-	-	-	-
MCLBJOKE_01084	4.43e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
MCLBJOKE_01085	3.09e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MCLBJOKE_01086	1.33e-188	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MCLBJOKE_01087	1.9e-30	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MCLBJOKE_01088	2.07e-156	pnb	-	-	C	-	-	-	nitroreductase
MCLBJOKE_01089	1.61e-114	-	-	-	-	-	-	-	-
MCLBJOKE_01090	1.54e-307	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
MCLBJOKE_01091	8.64e-49	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MCLBJOKE_01092	4.47e-116	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MCLBJOKE_01094	3.26e-63	-	-	-	-	-	-	-	-
MCLBJOKE_01095	1.98e-196	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCLBJOKE_01096	9.24e-186	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MCLBJOKE_01097	4.36e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
MCLBJOKE_01098	3.98e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MCLBJOKE_01100	2.57e-223	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MCLBJOKE_01101	4.28e-92	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MCLBJOKE_01102	3.37e-111	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MCLBJOKE_01103	9.33e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_01104	1.05e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MCLBJOKE_01105	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MCLBJOKE_01106	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MCLBJOKE_01107	2.82e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MCLBJOKE_01108	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MCLBJOKE_01109	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MCLBJOKE_01110	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MCLBJOKE_01111	7.1e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MCLBJOKE_01112	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MCLBJOKE_01113	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MCLBJOKE_01114	0.0	tdc	4.1.1.25	-	E	ko:K22330	ko00350,map00350	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
MCLBJOKE_01115	3.78e-263	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
MCLBJOKE_01116	1.04e-307	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
MCLBJOKE_01117	2.15e-298	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MCLBJOKE_01118	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MCLBJOKE_01119	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MCLBJOKE_01120	2.59e-175	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MCLBJOKE_01121	2.41e-179	-	-	-	S	-	-	-	Membrane
MCLBJOKE_01122	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
MCLBJOKE_01123	4.85e-29	-	-	-	-	-	-	-	-
MCLBJOKE_01124	2.47e-112	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MCLBJOKE_01125	7.66e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MCLBJOKE_01126	5.13e-61	-	-	-	-	-	-	-	-
MCLBJOKE_01127	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
MCLBJOKE_01128	1.4e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
MCLBJOKE_01129	2.42e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
MCLBJOKE_01130	5.75e-122	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
MCLBJOKE_01131	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MCLBJOKE_01132	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MCLBJOKE_01133	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
MCLBJOKE_01134	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCLBJOKE_01135	1.49e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MCLBJOKE_01136	2.21e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MCLBJOKE_01137	1.21e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
MCLBJOKE_01138	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MCLBJOKE_01139	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MCLBJOKE_01140	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MCLBJOKE_01141	4.45e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCLBJOKE_01142	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MCLBJOKE_01143	7.36e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MCLBJOKE_01144	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MCLBJOKE_01145	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MCLBJOKE_01146	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MCLBJOKE_01147	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCLBJOKE_01148	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MCLBJOKE_01149	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MCLBJOKE_01150	5.4e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MCLBJOKE_01151	1.62e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MCLBJOKE_01152	1.11e-164	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MCLBJOKE_01153	3.33e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MCLBJOKE_01154	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MCLBJOKE_01155	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MCLBJOKE_01156	1.49e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MCLBJOKE_01157	3.12e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MCLBJOKE_01158	2.26e-209	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MCLBJOKE_01159	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MCLBJOKE_01160	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MCLBJOKE_01161	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
MCLBJOKE_01162	8.08e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MCLBJOKE_01164	3.26e-296	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
MCLBJOKE_01165	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MCLBJOKE_01166	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MCLBJOKE_01167	1.78e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MCLBJOKE_01168	2.24e-237	ampC	-	-	V	-	-	-	Beta-lactamase
MCLBJOKE_01169	9.26e-77	-	-	-	-	-	-	-	-
MCLBJOKE_01170	0.0	-	-	-	M	-	-	-	domain protein
MCLBJOKE_01171	1.84e-130	-	-	-	-	-	-	-	-
MCLBJOKE_01173	2.3e-46	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MCLBJOKE_01174	1.62e-193	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MCLBJOKE_01175	1.28e-75	-	-	-	-	-	-	-	-
MCLBJOKE_01177	5.43e-114	-	-	-	-	-	-	-	-
MCLBJOKE_01178	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MCLBJOKE_01179	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
MCLBJOKE_01180	3.35e-75	-	-	-	S	-	-	-	Cupredoxin-like domain
MCLBJOKE_01181	1.72e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MCLBJOKE_01182	5.49e-207	-	-	-	EG	-	-	-	EamA-like transporter family
MCLBJOKE_01183	4.6e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MCLBJOKE_01184	3.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MCLBJOKE_01185	2.61e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
MCLBJOKE_01186	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
MCLBJOKE_01187	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MCLBJOKE_01188	8.8e-17	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
MCLBJOKE_01189	7.22e-28	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
MCLBJOKE_01190	0.0	-	-	-	G	-	-	-	Right handed beta helix region
MCLBJOKE_01191	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MCLBJOKE_01192	2.57e-222	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
MCLBJOKE_01193	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MCLBJOKE_01195	3.53e-275	xylR	-	-	GK	-	-	-	ROK family
MCLBJOKE_01196	2.05e-38	-	-	-	-	-	-	-	-
MCLBJOKE_01197	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MCLBJOKE_01198	1.41e-152	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MCLBJOKE_01199	1.91e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MCLBJOKE_01200	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MCLBJOKE_01201	4.48e-171	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
MCLBJOKE_01203	1.27e-109	lytE	-	-	M	-	-	-	Lysin motif
MCLBJOKE_01204	4.13e-186	-	-	-	S	-	-	-	Cof-like hydrolase
MCLBJOKE_01205	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_01206	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MCLBJOKE_01207	5.17e-70	-	-	-	-	-	-	-	-
MCLBJOKE_01208	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MCLBJOKE_01209	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MCLBJOKE_01210	8.71e-164	ybbR	-	-	S	-	-	-	YbbR-like protein
MCLBJOKE_01211	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MCLBJOKE_01212	1.33e-66	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MCLBJOKE_01213	8.49e-66	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
MCLBJOKE_01215	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MCLBJOKE_01216	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MCLBJOKE_01217	1.91e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MCLBJOKE_01218	9.24e-55	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
MCLBJOKE_01219	2.41e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
MCLBJOKE_01220	1.21e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MCLBJOKE_01221	4.34e-200	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MCLBJOKE_01222	2.44e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MCLBJOKE_01223	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MCLBJOKE_01224	1.44e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MCLBJOKE_01225	4.76e-35	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MCLBJOKE_01226	9.03e-148	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MCLBJOKE_01227	5.22e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MCLBJOKE_01228	2.29e-137	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
MCLBJOKE_01229	2.49e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_01230	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MCLBJOKE_01231	8.79e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
MCLBJOKE_01232	3.05e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_01233	4.88e-263	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MCLBJOKE_01234	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MCLBJOKE_01235	7.59e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MCLBJOKE_01236	7.41e-163	-	-	-	-	-	-	-	-
MCLBJOKE_01237	4.72e-72	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MCLBJOKE_01238	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MCLBJOKE_01240	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MCLBJOKE_01241	5.32e-109	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
MCLBJOKE_01242	5.89e-231	ydhF	-	-	S	-	-	-	Aldo keto reductase
MCLBJOKE_01243	1.68e-115	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
MCLBJOKE_01244	2.94e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
MCLBJOKE_01245	9.25e-247	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
MCLBJOKE_01246	3.41e-169	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
MCLBJOKE_01247	3.23e-145	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
MCLBJOKE_01248	5.84e-174	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MCLBJOKE_01249	1.71e-131	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
MCLBJOKE_01250	0.0	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MCLBJOKE_01251	1.56e-229	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
MCLBJOKE_01252	1.78e-210	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MCLBJOKE_01253	1.88e-291	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MCLBJOKE_01254	1.11e-101	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
MCLBJOKE_01255	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
MCLBJOKE_01256	5.9e-190	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
MCLBJOKE_01257	1.43e-151	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MCLBJOKE_01258	2.56e-70	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
MCLBJOKE_01259	8.97e-171	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
MCLBJOKE_01260	2.02e-157	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
MCLBJOKE_01261	6.89e-185	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
MCLBJOKE_01262	0.0	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
MCLBJOKE_01263	3e-171	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
MCLBJOKE_01264	3.53e-169	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
MCLBJOKE_01265	8.21e-246	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
MCLBJOKE_01266	3.78e-170	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
MCLBJOKE_01267	2.89e-124	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
MCLBJOKE_01268	2.01e-141	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
MCLBJOKE_01269	2.46e-270	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
MCLBJOKE_01270	2.8e-159	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
MCLBJOKE_01271	1.33e-228	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
MCLBJOKE_01272	0.0	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
MCLBJOKE_01273	1.47e-265	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
MCLBJOKE_01274	7.96e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
MCLBJOKE_01275	2.32e-198	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
MCLBJOKE_01276	2.54e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MCLBJOKE_01277	7.7e-95	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
MCLBJOKE_01278	9.36e-42	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MCLBJOKE_01279	2.81e-59	-	-	-	P	ko:K02031,ko:K02032,ko:K10823,ko:K13892,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MCLBJOKE_01280	1.51e-68	-	-	-	P	-	-	-	ABC transporter, permease protein
MCLBJOKE_01281	1.12e-55	-	-	-	P	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
MCLBJOKE_01282	6.29e-193	nikA	-	-	E	ko:K15584	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Nickel ABC transporter
MCLBJOKE_01283	3.99e-72	-	-	-	Q	-	-	-	Methyltransferase
MCLBJOKE_01284	0.0	arcT	-	-	E	-	-	-	Dipeptidase
MCLBJOKE_01285	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MCLBJOKE_01286	1.04e-218	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MCLBJOKE_01287	4.63e-159	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MCLBJOKE_01288	4.42e-141	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MCLBJOKE_01289	1.31e-210	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MCLBJOKE_01290	2.71e-219	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MCLBJOKE_01291	2.65e-108	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MCLBJOKE_01292	9.11e-208	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MCLBJOKE_01293	2.31e-229	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MCLBJOKE_01294	7.69e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MCLBJOKE_01295	1.08e-113	-	-	-	Q	-	-	-	Methyltransferase
MCLBJOKE_01296	3.26e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
MCLBJOKE_01297	1.37e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MCLBJOKE_01298	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MCLBJOKE_01299	2.31e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MCLBJOKE_01300	1.11e-285	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MCLBJOKE_01301	5.83e-309	-	-	-	M	-	-	-	Glycosyl transferase
MCLBJOKE_01302	3.87e-184	-	-	-	-	-	-	-	-
MCLBJOKE_01303	6.29e-100	-	-	-	-	-	-	-	-
MCLBJOKE_01304	1.62e-229	-	-	-	-	-	-	-	-
MCLBJOKE_01305	4.32e-235	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MCLBJOKE_01306	5.63e-179	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MCLBJOKE_01307	2.64e-167	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MCLBJOKE_01308	2.64e-103	-	-	-	S	-	-	-	Flavodoxin
MCLBJOKE_01309	2.29e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
MCLBJOKE_01310	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
MCLBJOKE_01311	3.17e-280	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
MCLBJOKE_01312	1.93e-212	-	-	-	H	-	-	-	geranyltranstransferase activity
MCLBJOKE_01313	6.39e-233	-	-	-	-	-	-	-	-
MCLBJOKE_01314	3.11e-26	-	-	-	-	-	-	-	-
MCLBJOKE_01315	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
MCLBJOKE_01316	1.77e-240	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
MCLBJOKE_01317	6.37e-60	-	-	-	-	-	-	-	-
MCLBJOKE_01318	4.78e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MCLBJOKE_01319	2.28e-108	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MCLBJOKE_01320	8.56e-289	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
MCLBJOKE_01321	1.85e-104	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MCLBJOKE_01322	8.49e-242	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
MCLBJOKE_01323	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MCLBJOKE_01324	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MCLBJOKE_01325	1.21e-129	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
MCLBJOKE_01326	4.68e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
MCLBJOKE_01327	4.43e-195	-	-	-	EG	-	-	-	EamA-like transporter family
MCLBJOKE_01328	4.68e-152	-	-	-	L	-	-	-	Integrase
MCLBJOKE_01329	7.24e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MCLBJOKE_01331	1.72e-246	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
MCLBJOKE_01332	5.19e-56	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
MCLBJOKE_01333	2.89e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MCLBJOKE_01334	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MCLBJOKE_01335	3.01e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MCLBJOKE_01336	1.86e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MCLBJOKE_01337	1.91e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MCLBJOKE_01338	2.06e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
MCLBJOKE_01339	6.63e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCLBJOKE_01340	6.72e-183	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MCLBJOKE_01341	2.61e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
MCLBJOKE_01342	3.46e-95	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCLBJOKE_01343	1.65e-55	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MCLBJOKE_01344	2.25e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MCLBJOKE_01345	3.44e-146	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MCLBJOKE_01346	2.3e-167	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MCLBJOKE_01347	2.54e-101	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MCLBJOKE_01348	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
MCLBJOKE_01349	2.83e-84	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
MCLBJOKE_01350	3.44e-60	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
MCLBJOKE_01351	9.52e-124	-	-	-	S	-	-	-	AmiS/UreI family transporter
MCLBJOKE_01352	1.06e-276	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MCLBJOKE_01354	1.24e-215	-	-	-	-	-	-	-	-
MCLBJOKE_01355	1.57e-124	-	-	-	K	-	-	-	acetyltransferase
MCLBJOKE_01356	3.3e-31	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCLBJOKE_01357	1.17e-19	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCLBJOKE_01359	1.35e-127	-	-	-	-	-	-	-	-
MCLBJOKE_01360	2.03e-81	-	-	-	-	-	-	-	-
MCLBJOKE_01361	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MCLBJOKE_01362	4.94e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MCLBJOKE_01363	1.81e-89	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MCLBJOKE_01367	2.11e-30	-	-	-	E	-	-	-	Pfam:DUF955
MCLBJOKE_01368	5.69e-16	-	-	-	S	-	-	-	Protein conserved in bacteria
MCLBJOKE_01369	5.44e-31	-	-	-	-	-	-	-	-
MCLBJOKE_01370	6.91e-25	-	-	-	-	-	-	-	-
MCLBJOKE_01371	3.22e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
MCLBJOKE_01372	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCLBJOKE_01373	2.6e-234	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MCLBJOKE_01374	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCLBJOKE_01375	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MCLBJOKE_01376	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MCLBJOKE_01377	6.4e-260	camS	-	-	S	-	-	-	sex pheromone
MCLBJOKE_01378	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MCLBJOKE_01379	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MCLBJOKE_01380	2.19e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MCLBJOKE_01381	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MCLBJOKE_01382	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MCLBJOKE_01383	1.56e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MCLBJOKE_01386	2.18e-105	-	-	-	S	-	-	-	GIY-YIG catalytic domain
MCLBJOKE_01387	1.05e-150	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MCLBJOKE_01388	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MCLBJOKE_01391	0.0	snf	-	-	KL	-	-	-	domain protein
MCLBJOKE_01392	9.06e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MCLBJOKE_01393	9.09e-25	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MCLBJOKE_01394	2.25e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MCLBJOKE_01395	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
MCLBJOKE_01396	6.42e-139	-	-	-	L	-	-	-	nuclease
MCLBJOKE_01397	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MCLBJOKE_01398	3.69e-92	-	-	-	-	-	-	-	-
MCLBJOKE_01399	5.83e-133	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MCLBJOKE_01400	6.27e-155	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MCLBJOKE_01401	1.06e-193	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MCLBJOKE_01402	2.26e-23	-	-	-	-	-	-	-	-
MCLBJOKE_01403	7.05e-54	-	-	-	-	-	-	-	-
MCLBJOKE_01404	5.12e-120	-	-	-	-	-	-	-	-
MCLBJOKE_01406	1.48e-42	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MCLBJOKE_01408	1.65e-148	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
MCLBJOKE_01409	1.77e-63	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
MCLBJOKE_01410	1.58e-146	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MCLBJOKE_01412	3.25e-40	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MCLBJOKE_01413	8.64e-61	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MCLBJOKE_01414	2.21e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MCLBJOKE_01415	3.4e-118	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MCLBJOKE_01416	7.88e-245	flp	-	-	V	-	-	-	Beta-lactamase
MCLBJOKE_01417	2.08e-96	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCLBJOKE_01418	1.48e-114	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MCLBJOKE_01419	2.82e-24	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MCLBJOKE_01420	5.09e-153	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MCLBJOKE_01421	3.81e-263	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MCLBJOKE_01425	4e-55	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MCLBJOKE_01426	3.03e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MCLBJOKE_01427	1.42e-304	-	-	-	T	-	-	-	GHKL domain
MCLBJOKE_01428	5.37e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MCLBJOKE_01429	3.15e-141	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
MCLBJOKE_01430	1.94e-13	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MCLBJOKE_01431	3.88e-71	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MCLBJOKE_01432	6.19e-40	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
MCLBJOKE_01433	4.65e-140	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
MCLBJOKE_01434	8.18e-94	-	-	-	C	-	-	-	Flavodoxin
MCLBJOKE_01435	1.34e-118	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MCLBJOKE_01436	2.34e-51	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MCLBJOKE_01437	1.11e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MCLBJOKE_01438	9.16e-202	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MCLBJOKE_01439	5.03e-166	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MCLBJOKE_01440	1.45e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MCLBJOKE_01441	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MCLBJOKE_01442	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MCLBJOKE_01443	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MCLBJOKE_01444	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MCLBJOKE_01445	1.06e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MCLBJOKE_01446	3.11e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MCLBJOKE_01447	7.06e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MCLBJOKE_01448	7.1e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MCLBJOKE_01449	7.15e-232	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MCLBJOKE_01450	1.64e-215	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MCLBJOKE_01451	2.87e-95	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MCLBJOKE_01452	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MCLBJOKE_01453	1.46e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MCLBJOKE_01454	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MCLBJOKE_01455	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MCLBJOKE_01456	2.49e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MCLBJOKE_01457	9.65e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCLBJOKE_01458	3.3e-200	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCLBJOKE_01459	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MCLBJOKE_01460	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MCLBJOKE_01461	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCLBJOKE_01462	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MCLBJOKE_01463	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MCLBJOKE_01464	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MCLBJOKE_01465	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MCLBJOKE_01466	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MCLBJOKE_01467	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MCLBJOKE_01468	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MCLBJOKE_01469	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MCLBJOKE_01470	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MCLBJOKE_01471	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MCLBJOKE_01472	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MCLBJOKE_01473	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MCLBJOKE_01474	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MCLBJOKE_01475	3.02e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MCLBJOKE_01476	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MCLBJOKE_01477	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MCLBJOKE_01478	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MCLBJOKE_01479	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MCLBJOKE_01480	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MCLBJOKE_01481	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MCLBJOKE_01482	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MCLBJOKE_01483	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MCLBJOKE_01484	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MCLBJOKE_01485	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MCLBJOKE_01486	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MCLBJOKE_01487	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MCLBJOKE_01488	3.46e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MCLBJOKE_01489	5.76e-228	-	-	-	-	-	-	-	-
MCLBJOKE_01490	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MCLBJOKE_01491	1.31e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MCLBJOKE_01492	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MCLBJOKE_01493	1.13e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MCLBJOKE_01494	2.73e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MCLBJOKE_01495	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MCLBJOKE_01496	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCLBJOKE_01497	3.84e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCLBJOKE_01498	1.84e-49	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MCLBJOKE_01499	7.43e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MCLBJOKE_01500	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MCLBJOKE_01501	6.36e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MCLBJOKE_01502	5.18e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MCLBJOKE_01503	7.09e-163	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
MCLBJOKE_01504	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MCLBJOKE_01505	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MCLBJOKE_01506	9.6e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
MCLBJOKE_01507	2.33e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MCLBJOKE_01508	7.47e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MCLBJOKE_01509	2.61e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MCLBJOKE_01510	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MCLBJOKE_01511	3.93e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MCLBJOKE_01512	4.11e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MCLBJOKE_01513	7.35e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MCLBJOKE_01514	1.44e-179	-	-	-	K	-	-	-	LysR substrate binding domain
MCLBJOKE_01515	9.94e-71	-	-	-	S	-	-	-	branched-chain amino acid
MCLBJOKE_01516	1.32e-183	-	-	-	E	-	-	-	AzlC protein
MCLBJOKE_01517	1.85e-264	hpk31	-	-	T	-	-	-	Histidine kinase
MCLBJOKE_01518	9.76e-161	vanR	-	-	K	-	-	-	response regulator
MCLBJOKE_01519	6.97e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MCLBJOKE_01520	1.54e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
MCLBJOKE_01521	1.89e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MCLBJOKE_01522	1.65e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MCLBJOKE_01523	2.8e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MCLBJOKE_01524	8.01e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MCLBJOKE_01525	4.25e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MCLBJOKE_01526	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MCLBJOKE_01527	1.17e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MCLBJOKE_01528	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MCLBJOKE_01529	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MCLBJOKE_01530	6.46e-201	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MCLBJOKE_01531	9.32e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MCLBJOKE_01532	2.08e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MCLBJOKE_01533	4.78e-218	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MCLBJOKE_01534	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
MCLBJOKE_01535	5.06e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MCLBJOKE_01537	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_01538	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCLBJOKE_01539	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MCLBJOKE_01540	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MCLBJOKE_01541	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
MCLBJOKE_01542	1.32e-220	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MCLBJOKE_01543	7.05e-273	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MCLBJOKE_01544	8.11e-138	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MCLBJOKE_01545	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MCLBJOKE_01546	6.91e-235	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
MCLBJOKE_01547	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MCLBJOKE_01548	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MCLBJOKE_01549	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MCLBJOKE_01550	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
MCLBJOKE_01551	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
MCLBJOKE_01552	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MCLBJOKE_01553	4.06e-93	-	-	-	-	-	-	-	-
MCLBJOKE_01554	4.64e-142	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
MCLBJOKE_01555	6.4e-314	-	-	-	E	-	-	-	amino acid
MCLBJOKE_01556	1.89e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MCLBJOKE_01558	1.1e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MCLBJOKE_01559	6.29e-129	-	-	-	-	-	-	-	-
MCLBJOKE_01560	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MCLBJOKE_01561	4.32e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MCLBJOKE_01562	1.33e-66	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MCLBJOKE_01563	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MCLBJOKE_01564	1.67e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MCLBJOKE_01565	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MCLBJOKE_01566	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MCLBJOKE_01567	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
MCLBJOKE_01568	1.77e-56	-	-	-	-	-	-	-	-
MCLBJOKE_01569	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MCLBJOKE_01570	3.36e-44	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MCLBJOKE_01571	1.55e-135	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MCLBJOKE_01572	5.56e-196	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MCLBJOKE_01573	3.18e-45	-	-	-	-	-	-	-	-
MCLBJOKE_01574	1.42e-203	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MCLBJOKE_01575	1.58e-16	-	-	-	G	-	-	-	Major Facilitator
MCLBJOKE_01576	8.92e-67	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MCLBJOKE_01577	1.45e-161	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MCLBJOKE_01578	8.39e-165	-	-	-	G	-	-	-	Major Facilitator Superfamily
MCLBJOKE_01579	2.93e-08	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
MCLBJOKE_01580	7.37e-273	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MCLBJOKE_01581	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MCLBJOKE_01582	4.46e-147	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
MCLBJOKE_01583	6.83e-226	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
MCLBJOKE_01585	0.0	-	-	-	L	-	-	-	PLD-like domain
MCLBJOKE_01586	1.85e-22	-	-	-	-	-	-	-	-
MCLBJOKE_01587	1.14e-121	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
MCLBJOKE_01588	4.75e-215	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
MCLBJOKE_01589	4.19e-112	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain protein
MCLBJOKE_01590	1.02e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MCLBJOKE_01591	1.45e-81	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
MCLBJOKE_01592	2.89e-247	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MCLBJOKE_01593	5.21e-103	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MCLBJOKE_01594	1.68e-189	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MCLBJOKE_01595	4.3e-256	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
MCLBJOKE_01596	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MCLBJOKE_01598	2.76e-76	-	-	-	-	-	-	-	-
MCLBJOKE_01599	1.19e-231	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MCLBJOKE_01600	1.08e-161	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MCLBJOKE_01601	5.61e-71	-	-	-	-	-	-	-	-
MCLBJOKE_01602	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MCLBJOKE_01603	1.54e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MCLBJOKE_01604	1.04e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MCLBJOKE_01605	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MCLBJOKE_01606	1.05e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_01607	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MCLBJOKE_01608	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MCLBJOKE_01609	1.11e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MCLBJOKE_01610	7.52e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MCLBJOKE_01611	1.94e-24	-	-	-	-	-	-	-	-
MCLBJOKE_01612	0.00028	-	-	-	D	-	-	-	nuclear chromosome segregation
MCLBJOKE_01614	9.82e-54	lytE	-	-	M	-	-	-	Lysin motif
MCLBJOKE_01616	2.1e-69	-	-	-	-	-	-	-	-
MCLBJOKE_01618	1.08e-63	-	-	-	L	-	-	-	four-way junction helicase activity
MCLBJOKE_01619	1.07e-32	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
MCLBJOKE_01620	5.56e-34	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
MCLBJOKE_01625	2.06e-21	-	-	-	-	-	-	-	-
MCLBJOKE_01626	3.7e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MCLBJOKE_01631	7.13e-119	-	-	-	L	-	-	-	Integrase
MCLBJOKE_01632	1.99e-66	-	-	-	L	-	-	-	Lactococcus lactis RepB C-terminus
MCLBJOKE_01634	5.67e-129	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
MCLBJOKE_01635	1.17e-48	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
MCLBJOKE_01636	1.54e-104	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MCLBJOKE_01641	1.8e-63	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	DNA mismatch endonuclease Vsr
MCLBJOKE_01642	2.07e-197	nlaXM	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	cytosine-specific methyltransferase
MCLBJOKE_01643	1.96e-125	-	-	-	S	-	-	-	NgoFVII restriction endonuclease
MCLBJOKE_01645	1.73e-56	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MCLBJOKE_01646	1.52e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
MCLBJOKE_01647	1.06e-88	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCLBJOKE_01648	9.17e-71	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
MCLBJOKE_01649	3.39e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
MCLBJOKE_01650	1.6e-07	-	-	-	E	-	-	-	Protein of unknown function (DUF3923)
MCLBJOKE_01652	9.11e-94	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MCLBJOKE_01654	3.19e-21	-	-	-	K	-	-	-	Peptidase S24-like
MCLBJOKE_01659	4.98e-35	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MCLBJOKE_01679	4.9e-05	-	-	-	S	-	-	-	YopX protein
MCLBJOKE_01684	1.41e-243	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
MCLBJOKE_01685	1.07e-112	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
MCLBJOKE_01686	1.38e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MCLBJOKE_01687	1.21e-147	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_01688	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_01689	4.81e-50	-	-	-	-	-	-	-	-
MCLBJOKE_01690	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MCLBJOKE_01691	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MCLBJOKE_01692	5.15e-219	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MCLBJOKE_01693	2.6e-33	-	-	-	-	-	-	-	-
MCLBJOKE_01694	2.43e-145	-	-	-	-	-	-	-	-
MCLBJOKE_01695	1.2e-267	yttB	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_01696	9.3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MCLBJOKE_01697	7.05e-113	-	-	-	-	-	-	-	-
MCLBJOKE_01698	3.39e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MCLBJOKE_01699	1.27e-247	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MCLBJOKE_01700	1.23e-255	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
MCLBJOKE_01701	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MCLBJOKE_01702	1.82e-137	-	-	-	M	-	-	-	biosynthesis protein
MCLBJOKE_01703	6.35e-276	cps3F	-	-	-	-	-	-	-
MCLBJOKE_01704	2.22e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MCLBJOKE_01705	7.46e-149	-	-	-	M	-	-	-	Bacterial sugar transferase
MCLBJOKE_01706	1e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MCLBJOKE_01707	1.91e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MCLBJOKE_01708	3.12e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MCLBJOKE_01709	7.27e-42	-	-	-	-	-	-	-	-
MCLBJOKE_01710	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MCLBJOKE_01711	1.83e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MCLBJOKE_01712	0.0	potE	-	-	E	-	-	-	Amino Acid
MCLBJOKE_01713	3.08e-162	-	3.2.1.23, 3.2.1.89	-	G	ko:K01190,ko:K01224	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	arabinogalactan endo-1,4-beta-galactosidase activity
MCLBJOKE_01714	1.63e-82	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
MCLBJOKE_01715	2.92e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_01716	9.18e-145	-	-	-	-	-	-	-	-
MCLBJOKE_01717	3.86e-182	-	-	-	G	-	-	-	MucBP domain
MCLBJOKE_01718	4.48e-130	-	-	-	S	-	-	-	Pfam:DUF3816
MCLBJOKE_01719	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MCLBJOKE_01720	9.69e-38	-	-	-	-	-	-	-	-
MCLBJOKE_01721	5.05e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MCLBJOKE_01722	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MCLBJOKE_01723	2.1e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MCLBJOKE_01724	7.98e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MCLBJOKE_01725	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MCLBJOKE_01726	3.22e-287	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MCLBJOKE_01727	1.16e-166	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
MCLBJOKE_01728	5.17e-252	yueF	-	-	S	-	-	-	AI-2E family transporter
MCLBJOKE_01729	1.89e-54	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MCLBJOKE_01730	5.7e-279	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MCLBJOKE_01731	1.5e-292	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MCLBJOKE_01732	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MCLBJOKE_01734	1.83e-60	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
MCLBJOKE_01735	1.95e-115	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MCLBJOKE_01737	7.66e-07	-	2.7.13.3, 2.7.7.7, 5.4.99.21	-	D	ko:K02343,ko:K03407,ko:K06182,ko:K08372,ko:K12065,ko:K16291	ko00230,ko00240,ko01100,ko02020,ko02030,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map02030,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko02022,ko02035,ko02044,ko03009,ko03032,ko03400	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MCLBJOKE_01738	8.79e-33	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
MCLBJOKE_01740	6.76e-63	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
MCLBJOKE_01741	7.04e-162	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
MCLBJOKE_01743	4.42e-180	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MCLBJOKE_01748	1.82e-230	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MCLBJOKE_01752	4.13e-221	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MCLBJOKE_01754	2.32e-36	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
MCLBJOKE_01761	9.98e-64	-	-	-	E	-	-	-	Filamentation induced by cAMP protein fic
MCLBJOKE_01762	3.81e-98	-	-	-	S	-	-	-	Fic/DOC family
MCLBJOKE_01763	5.71e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MCLBJOKE_01764	4.41e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MCLBJOKE_01765	4.87e-203	-	-	-	-	-	-	-	-
MCLBJOKE_01766	2.13e-232	-	-	-	-	-	-	-	-
MCLBJOKE_01767	9.54e-113	-	-	-	S	-	-	-	Protein conserved in bacteria
MCLBJOKE_01770	5.7e-146	-	-	-	K	-	-	-	Transcriptional regulator
MCLBJOKE_01771	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MCLBJOKE_01772	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MCLBJOKE_01773	7.2e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MCLBJOKE_01774	7.14e-166	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MCLBJOKE_01775	4.13e-254	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MCLBJOKE_01776	9.21e-143	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
MCLBJOKE_01777	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MCLBJOKE_01778	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MCLBJOKE_01779	6.56e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MCLBJOKE_01780	4.26e-307	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCLBJOKE_01781	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MCLBJOKE_01782	6.13e-199	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MCLBJOKE_01783	9.79e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MCLBJOKE_01784	4.54e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MCLBJOKE_01785	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MCLBJOKE_01786	7.4e-71	-	-	-	-	-	-	-	-
MCLBJOKE_01787	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MCLBJOKE_01788	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MCLBJOKE_01789	2.74e-267	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MCLBJOKE_01790	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MCLBJOKE_01791	4.98e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MCLBJOKE_01792	1.63e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MCLBJOKE_01793	8.61e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MCLBJOKE_01794	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MCLBJOKE_01795	1.03e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MCLBJOKE_01796	1.83e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MCLBJOKE_01797	1.35e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MCLBJOKE_01798	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MCLBJOKE_01799	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MCLBJOKE_01800	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MCLBJOKE_01801	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MCLBJOKE_01802	5.28e-238	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MCLBJOKE_01803	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MCLBJOKE_01804	5.24e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MCLBJOKE_01805	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MCLBJOKE_01806	5.07e-282	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MCLBJOKE_01807	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MCLBJOKE_01808	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MCLBJOKE_01809	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MCLBJOKE_01810	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MCLBJOKE_01811	2.09e-116	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MCLBJOKE_01812	7.76e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MCLBJOKE_01813	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
MCLBJOKE_01814	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MCLBJOKE_01815	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MCLBJOKE_01816	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MCLBJOKE_01817	1.06e-235	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MCLBJOKE_01818	3.81e-110	-	-	-	-	-	-	-	-
MCLBJOKE_01819	2.17e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MCLBJOKE_01820	1.49e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
MCLBJOKE_01821	2.02e-47	-	-	-	-	-	-	-	-
MCLBJOKE_01822	7.19e-198	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MCLBJOKE_01825	3.34e-52	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MCLBJOKE_01826	0.0	-	-	-	S	ko:K07459	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MCLBJOKE_01827	1.07e-263	-	-	-	L	-	-	-	DNA helicase
MCLBJOKE_01829	2.3e-142	-	-	-	I	-	-	-	Acid phosphatase homologues
MCLBJOKE_01830	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MCLBJOKE_01831	1.61e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
MCLBJOKE_01832	5.7e-153	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MCLBJOKE_01833	3.39e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MCLBJOKE_01834	1.62e-22	-	-	-	L	-	-	-	Phage integrase family
MCLBJOKE_01835	6.35e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MCLBJOKE_01836	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
MCLBJOKE_01837	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MCLBJOKE_01838	1.69e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MCLBJOKE_01840	1.24e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MCLBJOKE_01841	7.3e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MCLBJOKE_01842	2.39e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCLBJOKE_01844	1.62e-45	-	-	-	L	-	-	-	HNH endonuclease domain protein
MCLBJOKE_01845	7.52e-148	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MCLBJOKE_01848	5.31e-32	-	-	-	N	ko:K07339	-	ko00000,ko01000,ko02048	mRNA binding
MCLBJOKE_01849	4.33e-76	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MCLBJOKE_01850	1.06e-208	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MCLBJOKE_01851	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
MCLBJOKE_01852	3.67e-232	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
MCLBJOKE_01853	3.51e-193	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MCLBJOKE_01854	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MCLBJOKE_01855	5.93e-265	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MCLBJOKE_01856	1.56e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MCLBJOKE_01857	1.17e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MCLBJOKE_01858	9.22e-104	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MCLBJOKE_01860	7.27e-272	isp	-	-	L	-	-	-	Transposase
MCLBJOKE_01861	1.7e-116	-	-	-	L	-	-	-	Integrase
MCLBJOKE_01862	2.47e-112	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MCLBJOKE_01863	2.02e-22	-	-	-	K	-	-	-	Transcriptional regulator, LacI family
MCLBJOKE_01864	8.25e-250	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MCLBJOKE_01865	1.87e-74	-	-	-	S	-	-	-	Pfam:DUF59
MCLBJOKE_01866	9.36e-42	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MCLBJOKE_01868	4.86e-07	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
MCLBJOKE_01870	1.91e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
MCLBJOKE_01872	9.77e-27	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MCLBJOKE_01873	6.83e-87	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MCLBJOKE_01874	6.79e-44	-	-	-	K	-	-	-	DNA binding
MCLBJOKE_01875	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
MCLBJOKE_01876	3.85e-154	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
MCLBJOKE_01877	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MCLBJOKE_01878	2.53e-240	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MCLBJOKE_01879	2.18e-216	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MCLBJOKE_01880	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MCLBJOKE_01881	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MCLBJOKE_01882	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MCLBJOKE_01883	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
MCLBJOKE_01884	8.69e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MCLBJOKE_01885	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
MCLBJOKE_01886	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MCLBJOKE_01887	3.25e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MCLBJOKE_01888	3.84e-145	-	-	-	S	-	-	-	(CBS) domain
MCLBJOKE_01889	2.4e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
MCLBJOKE_01890	2.17e-306	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
MCLBJOKE_01891	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MCLBJOKE_01892	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MCLBJOKE_01893	3.78e-270	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MCLBJOKE_01894	2.57e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MCLBJOKE_01895	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MCLBJOKE_01896	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCLBJOKE_01897	3.03e-298	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MCLBJOKE_01898	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MCLBJOKE_01899	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MCLBJOKE_01900	4.04e-211	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MCLBJOKE_01901	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
MCLBJOKE_01902	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MCLBJOKE_01903	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MCLBJOKE_01904	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MCLBJOKE_01905	2.85e-122	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MCLBJOKE_01906	1.15e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MCLBJOKE_01907	3.7e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MCLBJOKE_01908	3.34e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MCLBJOKE_01909	4.1e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MCLBJOKE_01910	2.48e-161	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MCLBJOKE_01911	5.56e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MCLBJOKE_01912	3.91e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MCLBJOKE_01913	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MCLBJOKE_01914	3.89e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MCLBJOKE_01915	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MCLBJOKE_01916	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MCLBJOKE_01917	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MCLBJOKE_01918	2.79e-187	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
MCLBJOKE_01919	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
MCLBJOKE_01920	4.65e-190	yidA	-	-	S	-	-	-	hydrolase
MCLBJOKE_01921	2.39e-98	-	-	-	-	-	-	-	-
MCLBJOKE_01922	9.36e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MCLBJOKE_01923	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MCLBJOKE_01924	2.7e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MCLBJOKE_01925	3.54e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MCLBJOKE_01926	2.81e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MCLBJOKE_01927	4.95e-216	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MCLBJOKE_01928	2.34e-204	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MCLBJOKE_01929	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MCLBJOKE_01930	1.25e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MCLBJOKE_01931	2.87e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MCLBJOKE_01932	2.16e-199	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MCLBJOKE_01933	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MCLBJOKE_01934	9.56e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
MCLBJOKE_01936	1.69e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MCLBJOKE_01937	4.27e-225	-	-	-	-	-	-	-	-
MCLBJOKE_01938	7.91e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MCLBJOKE_01939	5.11e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MCLBJOKE_01940	1.85e-241	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MCLBJOKE_01941	3.45e-240	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
MCLBJOKE_01942	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
MCLBJOKE_01943	0.0	-	-	-	L	-	-	-	DNA helicase
MCLBJOKE_01944	3.69e-259	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MCLBJOKE_01945	2.47e-250	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MCLBJOKE_01946	1.51e-259	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MCLBJOKE_01947	8.43e-48	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
MCLBJOKE_01948	3.52e-58	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
MCLBJOKE_01949	5.62e-49	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
MCLBJOKE_01950	7.31e-39	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
MCLBJOKE_01952	3.86e-160	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MCLBJOKE_01953	3.2e-68	-	-	-	-	-	-	-	-
MCLBJOKE_01954	1.15e-173	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
MCLBJOKE_01955	1.6e-80	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
MCLBJOKE_01961	5.87e-11	-	-	-	-	-	-	-	-
MCLBJOKE_01962	1.01e-223	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MCLBJOKE_01963	9.84e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MCLBJOKE_01964	3.69e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MCLBJOKE_01965	2.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
MCLBJOKE_01966	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MCLBJOKE_01967	1.76e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MCLBJOKE_01968	1.41e-63	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MCLBJOKE_01969	2.9e-149	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MCLBJOKE_01970	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
MCLBJOKE_01971	8.44e-67	-	-	-	-	-	-	-	-
MCLBJOKE_01972	8.56e-236	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
MCLBJOKE_01973	9.87e-165	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
MCLBJOKE_01974	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
MCLBJOKE_01994	3.5e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
MCLBJOKE_01995	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
MCLBJOKE_01996	5.58e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
MCLBJOKE_01997	2e-283	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MCLBJOKE_01998	6.26e-96	-	-	-	-	-	-	-	-
MCLBJOKE_01999	7.41e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MCLBJOKE_02000	8.23e-39	-	-	-	-	-	-	-	-
MCLBJOKE_02001	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
MCLBJOKE_02002	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
MCLBJOKE_02003	1.57e-262	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
MCLBJOKE_02004	4.07e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MCLBJOKE_02005	3.16e-206	mleR	-	-	K	-	-	-	LysR family
MCLBJOKE_02006	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
MCLBJOKE_02007	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MCLBJOKE_02008	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MCLBJOKE_02009	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MCLBJOKE_02010	4.66e-201	-	-	-	K	-	-	-	LysR family
MCLBJOKE_02011	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MCLBJOKE_02012	1.91e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MCLBJOKE_02013	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_02014	4.87e-235	-	-	-	I	-	-	-	Alpha beta
MCLBJOKE_02015	2.28e-133	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MCLBJOKE_02016	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MCLBJOKE_02018	1.86e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MCLBJOKE_02019	3.46e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MCLBJOKE_02020	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MCLBJOKE_02021	3.21e-99	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MCLBJOKE_02022	2e-75	-	-	-	-	-	-	-	-
MCLBJOKE_02023	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MCLBJOKE_02024	3.69e-278	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MCLBJOKE_02025	1.04e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MCLBJOKE_02026	7.44e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MCLBJOKE_02027	1.1e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MCLBJOKE_02028	8.01e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MCLBJOKE_02029	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MCLBJOKE_02030	2.34e-142	-	-	-	S	-	-	-	VIT family
MCLBJOKE_02031	6.28e-153	-	-	-	S	-	-	-	membrane
MCLBJOKE_02032	2e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MCLBJOKE_02033	2.22e-159	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
MCLBJOKE_02034	8.84e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MCLBJOKE_02035	1.04e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
MCLBJOKE_02036	3.54e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MCLBJOKE_02037	6.58e-152	-	-	-	I	-	-	-	phosphatase
MCLBJOKE_02038	1.22e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MCLBJOKE_02039	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MCLBJOKE_02040	1.11e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MCLBJOKE_02046	7.59e-14	-	-	-	-	-	-	-	-
MCLBJOKE_02047	1.97e-230	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
MCLBJOKE_02048	2.56e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MCLBJOKE_02049	2.31e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MCLBJOKE_02050	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MCLBJOKE_02051	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MCLBJOKE_02052	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCLBJOKE_02053	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MCLBJOKE_02054	1.15e-263	-	-	-	-	-	-	-	-
MCLBJOKE_02055	2.79e-153	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
MCLBJOKE_02056	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MCLBJOKE_02057	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MCLBJOKE_02058	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MCLBJOKE_02059	3.45e-207	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MCLBJOKE_02060	4.73e-38	-	-	-	L	-	-	-	Transposase
MCLBJOKE_02061	2.65e-161	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
MCLBJOKE_02062	3.02e-179	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MCLBJOKE_02063	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
MCLBJOKE_02064	6.07e-199	-	-	-	S	-	-	-	Alpha beta hydrolase
MCLBJOKE_02065	5.95e-202	gspA	-	-	M	-	-	-	family 8
MCLBJOKE_02066	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MCLBJOKE_02067	7.18e-126	-	-	-	-	-	-	-	-
MCLBJOKE_02068	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
MCLBJOKE_02069	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MCLBJOKE_02070	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MCLBJOKE_02071	1.07e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MCLBJOKE_02072	1.68e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MCLBJOKE_02073	8.16e-93	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MCLBJOKE_02074	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
MCLBJOKE_02075	5.39e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
MCLBJOKE_02076	4.87e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MCLBJOKE_02077	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MCLBJOKE_02078	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MCLBJOKE_02079	7.62e-132	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MCLBJOKE_02080	1.21e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MCLBJOKE_02081	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MCLBJOKE_02082	6.64e-206	-	-	-	EG	-	-	-	EamA-like transporter family
MCLBJOKE_02083	6.82e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MCLBJOKE_02084	1.83e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MCLBJOKE_02085	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MCLBJOKE_02086	1.16e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
MCLBJOKE_02087	4.7e-215	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MCLBJOKE_02088	6.81e-273	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MCLBJOKE_02089	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MCLBJOKE_02090	6.82e-119	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MCLBJOKE_02091	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MCLBJOKE_02092	1.06e-235	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
MCLBJOKE_02093	6.28e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MCLBJOKE_02094	2.29e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MCLBJOKE_02095	3.6e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
MCLBJOKE_02096	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
MCLBJOKE_02097	1.18e-168	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
MCLBJOKE_02098	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
MCLBJOKE_02099	1.8e-190	-	-	-	O	-	-	-	Band 7 protein
MCLBJOKE_02100	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MCLBJOKE_02101	1.77e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MCLBJOKE_02102	1.18e-50	-	-	-	S	-	-	-	Cytochrome B5
MCLBJOKE_02103	3.34e-128	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
MCLBJOKE_02104	5.26e-203	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MCLBJOKE_02105	3.38e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MCLBJOKE_02106	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MCLBJOKE_02107	4.52e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MCLBJOKE_02108	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MCLBJOKE_02109	7.88e-304	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MCLBJOKE_02110	4.46e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MCLBJOKE_02111	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
MCLBJOKE_02112	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MCLBJOKE_02113	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MCLBJOKE_02114	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MCLBJOKE_02115	1.93e-84	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
MCLBJOKE_02116	8.27e-141	-	-	-	K	ko:K03091	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
MCLBJOKE_02117	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MCLBJOKE_02127	8.14e-237	isp	-	-	L	-	-	-	Transposase
MCLBJOKE_02128	3.93e-119	-	-	-	-	-	-	-	-
MCLBJOKE_02129	2.29e-223	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MCLBJOKE_02132	2.4e-53	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MCLBJOKE_02134	4.09e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MCLBJOKE_02135	2.27e-65	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MCLBJOKE_02136	2.66e-62	-	-	-	-	-	-	-	-
MCLBJOKE_02138	1.53e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MCLBJOKE_02139	1.98e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MCLBJOKE_02140	2.03e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MCLBJOKE_02141	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MCLBJOKE_02142	1.44e-187	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MCLBJOKE_02143	3.57e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
MCLBJOKE_02144	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MCLBJOKE_02145	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
MCLBJOKE_02146	1.1e-125	-	-	-	S	-	-	-	reductase
MCLBJOKE_02147	2.9e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MCLBJOKE_02148	1.84e-22	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MCLBJOKE_02149	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
MCLBJOKE_02150	2.46e-289	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MCLBJOKE_02151	1.46e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MCLBJOKE_02152	7.14e-193	yycI	-	-	S	-	-	-	YycH protein
MCLBJOKE_02153	8.68e-316	yycH	-	-	S	-	-	-	YycH protein
MCLBJOKE_02154	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MCLBJOKE_02155	2.6e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MCLBJOKE_02157	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MCLBJOKE_02158	1.81e-94	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
MCLBJOKE_02160	7.37e-156	-	-	-	S	-	-	-	Fic/DOC family
MCLBJOKE_02161	3.08e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
MCLBJOKE_02162	1.57e-71	-	-	-	-	-	-	-	-
MCLBJOKE_02163	8.85e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
MCLBJOKE_02164	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MCLBJOKE_02165	5.1e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MCLBJOKE_02166	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MCLBJOKE_02167	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MCLBJOKE_02168	5.93e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MCLBJOKE_02169	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MCLBJOKE_02170	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCLBJOKE_02171	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MCLBJOKE_02172	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MCLBJOKE_02173	4.46e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MCLBJOKE_02174	1.15e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MCLBJOKE_02175	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MCLBJOKE_02176	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MCLBJOKE_02177	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MCLBJOKE_02178	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MCLBJOKE_02179	1.47e-168	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
MCLBJOKE_02180	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MCLBJOKE_02181	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MCLBJOKE_02182	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MCLBJOKE_02183	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MCLBJOKE_02184	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MCLBJOKE_02185	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MCLBJOKE_02186	6.51e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
MCLBJOKE_02187	1.3e-203	-	-	-	S	-	-	-	reductase
MCLBJOKE_02189	8.73e-11	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
MCLBJOKE_02191	1.3e-71	-	-	-	K	-	-	-	LysR substrate binding domain
MCLBJOKE_02192	0.0	-	-	-	S	-	-	-	amidohydrolase
MCLBJOKE_02194	1.91e-42	blpT	-	-	-	-	-	-	-
MCLBJOKE_02195	1.08e-53	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MCLBJOKE_02196	1.2e-26	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MCLBJOKE_02198	7.4e-130	comA	-	-	V	ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain