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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MILEJKDO_00001	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MILEJKDO_00002	6.35e-176	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MILEJKDO_00003	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MILEJKDO_00004	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MILEJKDO_00005	9.92e-265	yacL	-	-	S	-	-	-	domain protein
MILEJKDO_00006	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MILEJKDO_00007	6.9e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MILEJKDO_00008	1.93e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MILEJKDO_00009	7.17e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MILEJKDO_00010	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MILEJKDO_00011	4.28e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MILEJKDO_00012	3.52e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00013	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MILEJKDO_00014	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MILEJKDO_00015	1.54e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MILEJKDO_00016	1.24e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MILEJKDO_00017	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MILEJKDO_00018	6.15e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MILEJKDO_00019	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MILEJKDO_00021	1.16e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MILEJKDO_00022	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
MILEJKDO_00023	1.58e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MILEJKDO_00024	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MILEJKDO_00025	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
MILEJKDO_00026	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MILEJKDO_00027	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
MILEJKDO_00028	0.0	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_00029	3.81e-144	-	-	-	-	-	-	-	-
MILEJKDO_00032	4.13e-190	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MILEJKDO_00033	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MILEJKDO_00036	2.64e-92	-	-	-	C	-	-	-	Oxidoreductase
MILEJKDO_00037	7.39e-82	-	-	-	C	-	-	-	Oxidoreductase
MILEJKDO_00038	3.02e-80	-	-	-	S	-	-	-	macrophage migration inhibitory factor
MILEJKDO_00039	1.78e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MILEJKDO_00040	8.53e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MILEJKDO_00043	5.1e-186	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
MILEJKDO_00044	7.05e-45	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MILEJKDO_00051	3.09e-23	-	-	-	M	ko:K21449	-	ko00000,ko02000	Phage minor structural protein
MILEJKDO_00052	1.75e-175	-	-	-	M	-	-	-	Prophage endopeptidase tail
MILEJKDO_00053	7.93e-104	-	-	-	S	-	-	-	Phage tail protein
MILEJKDO_00054	2.62e-76	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MILEJKDO_00055	5.11e-248	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MILEJKDO_00056	5.82e-13	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
MILEJKDO_00057	1.25e-99	-	-	-	S	-	-	-	Phage tail tube protein
MILEJKDO_00061	6.4e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MILEJKDO_00062	2.28e-217	-	-	-	S	-	-	-	Phage capsid family
MILEJKDO_00063	2.25e-82	-	-	-	S	-	-	-	Clp protease
MILEJKDO_00064	2.71e-247	-	-	-	S	-	-	-	Phage portal protein
MILEJKDO_00065	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
MILEJKDO_00066	1.49e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
MILEJKDO_00067	5.98e-105	-	-	-	L	-	-	-	HNH nucleases
MILEJKDO_00069	4.14e-09	-	-	-	-	-	-	-	-
MILEJKDO_00071	3.15e-108	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MILEJKDO_00075	7.59e-17	-	-	-	-	-	-	-	-
MILEJKDO_00079	4.57e-164	-	-	-	-	-	-	-	-
MILEJKDO_00081	2.8e-92	-	-	-	-	-	-	-	-
MILEJKDO_00083	1.23e-183	-	-	-	L	-	-	-	DnaD domain protein
MILEJKDO_00086	8.04e-27	-	-	-	-	-	-	-	-
MILEJKDO_00090	4.03e-25	-	-	-	-	-	-	-	-
MILEJKDO_00091	3.08e-34	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MILEJKDO_00093	1.09e-26	-	-	-	-	-	-	-	-
MILEJKDO_00094	0.000616	-	-	-	S	-	-	-	SPFH domain-Band 7 family
MILEJKDO_00095	1.09e-66	-	-	-	S	-	-	-	AAA ATPase domain
MILEJKDO_00096	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MILEJKDO_00097	4.13e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MILEJKDO_00098	1.18e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MILEJKDO_00099	3.03e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MILEJKDO_00100	2.08e-48	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MILEJKDO_00101	4.55e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MILEJKDO_00102	8.43e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MILEJKDO_00103	8.95e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
MILEJKDO_00104	4.99e-58	-	-	-	-	-	-	-	-
MILEJKDO_00105	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
MILEJKDO_00106	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MILEJKDO_00107	7.95e-229	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MILEJKDO_00108	1.7e-234	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MILEJKDO_00109	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MILEJKDO_00110	1.15e-178	-	-	-	-	-	-	-	-
MILEJKDO_00111	2.41e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MILEJKDO_00112	1.26e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MILEJKDO_00113	1.68e-71	-	-	-	-	-	-	-	-
MILEJKDO_00114	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MILEJKDO_00115	2.65e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MILEJKDO_00116	1.91e-196	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MILEJKDO_00117	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
MILEJKDO_00118	1.29e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MILEJKDO_00119	3.47e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MILEJKDO_00120	1.89e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MILEJKDO_00121	1.43e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MILEJKDO_00122	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MILEJKDO_00123	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MILEJKDO_00124	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
MILEJKDO_00125	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MILEJKDO_00126	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MILEJKDO_00127	2.3e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MILEJKDO_00128	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MILEJKDO_00129	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MILEJKDO_00130	5.9e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MILEJKDO_00131	6.13e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MILEJKDO_00132	2.68e-252	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MILEJKDO_00133	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MILEJKDO_00134	6.16e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MILEJKDO_00135	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MILEJKDO_00136	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MILEJKDO_00137	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MILEJKDO_00138	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MILEJKDO_00139	1.15e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MILEJKDO_00140	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MILEJKDO_00141	9.26e-193	-	-	-	S	-	-	-	Helix-turn-helix domain
MILEJKDO_00142	4.81e-316	ymfH	-	-	S	-	-	-	Peptidase M16
MILEJKDO_00143	1.67e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MILEJKDO_00144	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MILEJKDO_00145	1.02e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00146	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MILEJKDO_00147	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
MILEJKDO_00148	1.1e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MILEJKDO_00149	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MILEJKDO_00150	1.41e-155	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MILEJKDO_00151	2.13e-312	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MILEJKDO_00152	1.05e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MILEJKDO_00153	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MILEJKDO_00154	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MILEJKDO_00155	8.07e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MILEJKDO_00156	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MILEJKDO_00157	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MILEJKDO_00158	1.37e-290	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MILEJKDO_00159	3.62e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MILEJKDO_00160	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MILEJKDO_00161	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MILEJKDO_00162	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MILEJKDO_00163	7.61e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MILEJKDO_00164	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
MILEJKDO_00165	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
MILEJKDO_00166	1.6e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MILEJKDO_00167	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MILEJKDO_00168	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MILEJKDO_00169	3.02e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MILEJKDO_00170	2.41e-179	-	-	-	S	-	-	-	Membrane
MILEJKDO_00171	1.16e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
MILEJKDO_00172	1.97e-28	-	-	-	-	-	-	-	-
MILEJKDO_00173	2.47e-112	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MILEJKDO_00174	6.57e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MILEJKDO_00175	3.61e-61	-	-	-	-	-	-	-	-
MILEJKDO_00176	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
MILEJKDO_00177	1.2e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
MILEJKDO_00178	1.15e-198	yvgN	-	-	S	-	-	-	Aldo keto reductase
MILEJKDO_00179	3.88e-120	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
MILEJKDO_00180	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MILEJKDO_00181	4.5e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MILEJKDO_00182	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
MILEJKDO_00183	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MILEJKDO_00184	6.07e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MILEJKDO_00185	3.13e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MILEJKDO_00186	2.02e-62	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
MILEJKDO_00187	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MILEJKDO_00188	3.8e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MILEJKDO_00189	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MILEJKDO_00190	8.98e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MILEJKDO_00191	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MILEJKDO_00192	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MILEJKDO_00193	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MILEJKDO_00194	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MILEJKDO_00195	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MILEJKDO_00196	7.99e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MILEJKDO_00197	6.21e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MILEJKDO_00198	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MILEJKDO_00199	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MILEJKDO_00200	8.02e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MILEJKDO_00201	3.32e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MILEJKDO_00202	9.53e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MILEJKDO_00203	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MILEJKDO_00204	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MILEJKDO_00205	2.58e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MILEJKDO_00206	5.39e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MILEJKDO_00207	3.9e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MILEJKDO_00208	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MILEJKDO_00209	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MILEJKDO_00210	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
MILEJKDO_00211	1.63e-171	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MILEJKDO_00212	4.84e-298	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
MILEJKDO_00213	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MILEJKDO_00214	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MILEJKDO_00215	8.44e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MILEJKDO_00216	4.91e-241	ampC	-	-	V	-	-	-	Beta-lactamase
MILEJKDO_00217	3.83e-74	-	-	-	-	-	-	-	-
MILEJKDO_00218	0.0	-	-	-	M	-	-	-	domain protein
MILEJKDO_00219	2.27e-138	-	-	-	-	-	-	-	-
MILEJKDO_00221	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MILEJKDO_00222	1.28e-75	-	-	-	-	-	-	-	-
MILEJKDO_00224	2.69e-114	-	-	-	-	-	-	-	-
MILEJKDO_00225	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MILEJKDO_00226	8.97e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
MILEJKDO_00227	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
MILEJKDO_00228	4.07e-133	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MILEJKDO_00229	1.38e-200	-	-	-	EG	-	-	-	EamA-like transporter family
MILEJKDO_00230	2.28e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MILEJKDO_00231	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MILEJKDO_00232	4.34e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
MILEJKDO_00233	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
MILEJKDO_00234	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MILEJKDO_00235	8.8e-17	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
MILEJKDO_00236	3.24e-58	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
MILEJKDO_00237	0.0	-	-	-	G	-	-	-	Right handed beta helix region
MILEJKDO_00238	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MILEJKDO_00239	1.81e-222	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
MILEJKDO_00240	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MILEJKDO_00242	5.23e-277	xylR	-	-	GK	-	-	-	ROK family
MILEJKDO_00243	2.49e-39	-	-	-	-	-	-	-	-
MILEJKDO_00244	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MILEJKDO_00245	5.54e-150	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MILEJKDO_00246	1.34e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MILEJKDO_00247	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MILEJKDO_00248	9.42e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
MILEJKDO_00250	1.31e-108	lytE	-	-	M	-	-	-	Lysin motif
MILEJKDO_00251	3.03e-188	-	-	-	S	-	-	-	Cof-like hydrolase
MILEJKDO_00252	1.23e-103	-	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_00253	0.0	oatA	-	-	I	-	-	-	Acyltransferase
MILEJKDO_00254	1.04e-69	-	-	-	-	-	-	-	-
MILEJKDO_00255	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MILEJKDO_00256	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MILEJKDO_00257	3.51e-161	ybbR	-	-	S	-	-	-	YbbR-like protein
MILEJKDO_00258	4.46e-193	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MILEJKDO_00259	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
MILEJKDO_00260	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MILEJKDO_00261	1.86e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MILEJKDO_00262	3.36e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MILEJKDO_00263	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MILEJKDO_00264	2.92e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MILEJKDO_00265	6.2e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MILEJKDO_00266	1.71e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MILEJKDO_00267	1.97e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MILEJKDO_00268	7.51e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MILEJKDO_00269	3.91e-136	-	-	-	-	-	-	-	-
MILEJKDO_00270	3.15e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MILEJKDO_00271	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MILEJKDO_00272	1.4e-188	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
MILEJKDO_00273	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MILEJKDO_00274	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MILEJKDO_00275	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MILEJKDO_00276	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MILEJKDO_00277	7.18e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MILEJKDO_00278	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MILEJKDO_00279	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MILEJKDO_00281	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MILEJKDO_00282	2.04e-308	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
MILEJKDO_00283	1.83e-21	-	-	-	-	-	-	-	-
MILEJKDO_00285	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MILEJKDO_00286	1.41e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MILEJKDO_00287	3.83e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MILEJKDO_00288	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MILEJKDO_00289	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MILEJKDO_00290	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MILEJKDO_00291	1.03e-19	-	-	-	-	-	-	-	-
MILEJKDO_00292	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MILEJKDO_00293	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MILEJKDO_00294	6.36e-277	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MILEJKDO_00295	2.31e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00296	2.47e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
MILEJKDO_00298	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MILEJKDO_00299	0.0	yhaN	-	-	L	-	-	-	AAA domain
MILEJKDO_00300	1.42e-270	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
MILEJKDO_00301	1.4e-63	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MILEJKDO_00302	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MILEJKDO_00303	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MILEJKDO_00304	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MILEJKDO_00305	1.65e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MILEJKDO_00307	1.49e-54	-	-	-	-	-	-	-	-
MILEJKDO_00308	2.19e-59	-	-	-	-	-	-	-	-
MILEJKDO_00309	2.47e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MILEJKDO_00310	5.53e-132	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MILEJKDO_00311	5.27e-281	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MILEJKDO_00312	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MILEJKDO_00313	6.46e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MILEJKDO_00314	2.89e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MILEJKDO_00315	2.57e-90	-	-	-	-	-	-	-	-
MILEJKDO_00317	9.17e-59	-	-	-	-	-	-	-	-
MILEJKDO_00318	1.43e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MILEJKDO_00319	1.52e-43	-	-	-	-	-	-	-	-
MILEJKDO_00320	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MILEJKDO_00321	2.41e-236	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
MILEJKDO_00322	1.53e-146	-	-	-	-	-	-	-	-
MILEJKDO_00323	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MILEJKDO_00324	3.04e-222	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MILEJKDO_00325	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MILEJKDO_00326	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MILEJKDO_00327	3.79e-191	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MILEJKDO_00328	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MILEJKDO_00329	8.42e-55	-	-	-	-	-	-	-	-
MILEJKDO_00330	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MILEJKDO_00331	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MILEJKDO_00332	1.97e-124	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MILEJKDO_00333	9.4e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
MILEJKDO_00334	7.28e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MILEJKDO_00335	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
MILEJKDO_00336	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
MILEJKDO_00337	6.52e-272	-	-	-	L	-	-	-	Integrase core domain
MILEJKDO_00338	2.98e-163	-	-	-	O	-	-	-	Bacterial dnaA protein
MILEJKDO_00340	9.91e-87	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
MILEJKDO_00341	4.74e-51	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
MILEJKDO_00343	0.0	snf	-	-	KL	-	-	-	domain protein
MILEJKDO_00344	1.44e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MILEJKDO_00345	4.75e-267	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MILEJKDO_00346	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
MILEJKDO_00347	4.33e-137	-	-	-	L	-	-	-	nuclease
MILEJKDO_00348	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MILEJKDO_00349	2.5e-90	-	-	-	-	-	-	-	-
MILEJKDO_00350	1.23e-134	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
MILEJKDO_00351	2.19e-155	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MILEJKDO_00352	2.91e-191	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MILEJKDO_00353	3.45e-35	-	-	-	-	-	-	-	-
MILEJKDO_00354	1.2e-76	-	-	-	-	-	-	-	-
MILEJKDO_00355	5.11e-120	-	-	-	-	-	-	-	-
MILEJKDO_00357	2.13e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MILEJKDO_00358	2.37e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MILEJKDO_00359	1.63e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MILEJKDO_00360	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MILEJKDO_00361	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MILEJKDO_00362	6.36e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MILEJKDO_00363	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MILEJKDO_00364	1.2e-59	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MILEJKDO_00365	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
MILEJKDO_00366	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MILEJKDO_00367	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MILEJKDO_00368	1.16e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MILEJKDO_00369	3.65e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MILEJKDO_00370	3.09e-85	-	-	-	-	-	-	-	-
MILEJKDO_00371	4.58e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MILEJKDO_00372	8.1e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MILEJKDO_00373	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MILEJKDO_00374	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MILEJKDO_00375	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MILEJKDO_00376	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MILEJKDO_00377	3.03e-256	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
MILEJKDO_00378	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MILEJKDO_00379	6.77e-77	-	-	-	-	-	-	-	-
MILEJKDO_00380	1.14e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MILEJKDO_00381	5.13e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MILEJKDO_00382	5.61e-71	-	-	-	-	-	-	-	-
MILEJKDO_00383	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MILEJKDO_00384	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MILEJKDO_00386	6.02e-219	-	-	-	S	-	-	-	Phage Mu protein F like protein
MILEJKDO_00387	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MILEJKDO_00388	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
MILEJKDO_00389	4.29e-29	-	-	-	-	-	-	-	-
MILEJKDO_00390	4.46e-78	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
MILEJKDO_00396	6.97e-35	-	-	-	-	-	-	-	-
MILEJKDO_00401	2.23e-20	-	-	-	-	-	-	-	-
MILEJKDO_00402	3.72e-104	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
MILEJKDO_00406	2.31e-21	-	-	-	-	-	-	-	-
MILEJKDO_00411	1.18e-50	-	-	-	S	-	-	-	ORF6C domain
MILEJKDO_00415	1.9e-31	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MILEJKDO_00416	5.58e-83	-	-	-	S	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
MILEJKDO_00417	4.55e-172	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
MILEJKDO_00421	3.3e-43	-	-	-	-	-	-	-	-
MILEJKDO_00422	2.02e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MILEJKDO_00423	4.31e-30	-	-	-	-	-	-	-	-
MILEJKDO_00428	0.000118	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
MILEJKDO_00429	1.39e-32	-	-	-	K	-	-	-	Helix-turn-helix domain
MILEJKDO_00432	1.28e-141	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
MILEJKDO_00433	6.29e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_00434	3.39e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MILEJKDO_00435	1.57e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MILEJKDO_00436	3.39e-293	-	-	-	P	-	-	-	Chloride transporter, ClC family
MILEJKDO_00437	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MILEJKDO_00438	5.65e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
MILEJKDO_00459	1.5e-78	isp	-	-	L	-	-	-	Transposase
MILEJKDO_00460	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MILEJKDO_00461	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MILEJKDO_00462	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MILEJKDO_00463	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
MILEJKDO_00464	3.69e-260	-	-	-	-	-	-	-	-
MILEJKDO_00465	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MILEJKDO_00466	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MILEJKDO_00467	1.21e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MILEJKDO_00468	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MILEJKDO_00469	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MILEJKDO_00470	5.17e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MILEJKDO_00471	1.19e-231	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
MILEJKDO_00477	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MILEJKDO_00478	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MILEJKDO_00480	9.35e-152	-	-	-	I	-	-	-	phosphatase
MILEJKDO_00481	3.68e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MILEJKDO_00482	5.6e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
MILEJKDO_00483	1.16e-29	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
MILEJKDO_00484	1.03e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MILEJKDO_00485	1.63e-152	-	-	-	L	-	-	-	Integrase
MILEJKDO_00486	7.34e-194	-	-	-	EG	-	-	-	EamA-like transporter family
MILEJKDO_00487	6.65e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
MILEJKDO_00488	2.34e-127	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
MILEJKDO_00489	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MILEJKDO_00490	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MILEJKDO_00491	2e-240	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
MILEJKDO_00492	1.78e-102	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MILEJKDO_00493	1.8e-290	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
MILEJKDO_00494	2.28e-108	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MILEJKDO_00495	4.78e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MILEJKDO_00496	6.37e-60	-	-	-	-	-	-	-	-
MILEJKDO_00497	1.77e-240	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
MILEJKDO_00498	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
MILEJKDO_00499	3.11e-26	-	-	-	-	-	-	-	-
MILEJKDO_00500	2.6e-232	-	-	-	-	-	-	-	-
MILEJKDO_00501	1.12e-211	-	-	-	H	-	-	-	geranyltranstransferase activity
MILEJKDO_00502	3.17e-280	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
MILEJKDO_00503	9.9e-49	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
MILEJKDO_00504	2.29e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
MILEJKDO_00505	1.79e-101	-	-	-	S	-	-	-	Flavodoxin
MILEJKDO_00506	1.52e-167	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MILEJKDO_00507	4.82e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MILEJKDO_00508	1.45e-233	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MILEJKDO_00509	1.62e-229	-	-	-	-	-	-	-	-
MILEJKDO_00510	1.54e-100	-	-	-	-	-	-	-	-
MILEJKDO_00511	1.13e-146	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MILEJKDO_00512	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
MILEJKDO_00513	1.02e-66	-	-	-	-	-	-	-	-
MILEJKDO_00514	1.15e-172	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MILEJKDO_00516	3.9e-14	-	-	-	-	-	-	-	-
MILEJKDO_00518	4.76e-114	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MILEJKDO_00519	7.31e-56	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MILEJKDO_00520	8.03e-71	-	-	-	S	-	-	-	Bacteriophage holin family
MILEJKDO_00521	3.1e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
MILEJKDO_00524	7.84e-234	-	-	-	S	-	-	-	Peptidase family M23
MILEJKDO_00525	3.05e-120	-	-	-	S	-	-	-	Phage tail protein
MILEJKDO_00526	0.0	-	-	-	D	-	-	-	domain protein
MILEJKDO_00527	3.01e-120	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
MILEJKDO_00528	2.42e-154	-	-	-	-	-	-	-	-
MILEJKDO_00529	1.35e-92	-	-	-	-	-	-	-	-
MILEJKDO_00530	1.17e-124	-	-	-	-	-	-	-	-
MILEJKDO_00531	1.54e-67	-	-	-	-	-	-	-	-
MILEJKDO_00532	1.04e-82	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MILEJKDO_00533	1.96e-252	gpG	-	-	-	-	-	-	-
MILEJKDO_00534	1.73e-119	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MILEJKDO_00535	1.79e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MILEJKDO_00536	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MILEJKDO_00537	2.57e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00538	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MILEJKDO_00539	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MILEJKDO_00540	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MILEJKDO_00541	2.15e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MILEJKDO_00542	3.59e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MILEJKDO_00543	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MILEJKDO_00544	2.99e-95	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MILEJKDO_00545	8.14e-216	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MILEJKDO_00546	6.13e-233	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MILEJKDO_00547	7.1e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MILEJKDO_00548	7.06e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MILEJKDO_00549	8.55e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MILEJKDO_00550	1.45e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MILEJKDO_00551	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MILEJKDO_00552	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MILEJKDO_00553	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MILEJKDO_00554	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MILEJKDO_00555	5.91e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MILEJKDO_00556	1.68e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MILEJKDO_00557	6.19e-200	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MILEJKDO_00558	4.04e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MILEJKDO_00559	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MILEJKDO_00560	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MILEJKDO_00561	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MILEJKDO_00562	3.23e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MILEJKDO_00563	2.45e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MILEJKDO_00564	2.49e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MILEJKDO_00565	1.67e-178	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MILEJKDO_00566	3.18e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MILEJKDO_00567	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MILEJKDO_00568	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MILEJKDO_00569	2.84e-241	-	-	-	S	-	-	-	Helix-turn-helix domain
MILEJKDO_00570	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MILEJKDO_00571	1.31e-65	-	-	-	M	-	-	-	Lysin motif
MILEJKDO_00572	7.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MILEJKDO_00573	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MILEJKDO_00574	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MILEJKDO_00575	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MILEJKDO_00576	5.26e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MILEJKDO_00577	3.33e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MILEJKDO_00578	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00579	5.75e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MILEJKDO_00580	3.79e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MILEJKDO_00581	4.3e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MILEJKDO_00582	9.07e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
MILEJKDO_00583	2.66e-218	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MILEJKDO_00584	5.52e-139	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
MILEJKDO_00585	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MILEJKDO_00586	7.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MILEJKDO_00587	1.01e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MILEJKDO_00588	6.17e-204	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MILEJKDO_00589	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MILEJKDO_00590	6.76e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MILEJKDO_00591	1.56e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MILEJKDO_00592	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MILEJKDO_00593	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MILEJKDO_00594	4.2e-110	-	-	-	F	-	-	-	Hydrolase, NUDIX family
MILEJKDO_00595	8.96e-223	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MILEJKDO_00596	3.67e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MILEJKDO_00597	5.5e-67	-	-	-	-	-	-	-	-
MILEJKDO_00599	3.93e-119	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MILEJKDO_00600	4.49e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MILEJKDO_00601	3.09e-35	-	-	-	-	-	-	-	-
MILEJKDO_00602	3.97e-125	-	-	-	-	-	-	-	-
MILEJKDO_00603	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MILEJKDO_00604	8.65e-230	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
MILEJKDO_00605	2.44e-280	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
MILEJKDO_00606	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MILEJKDO_00607	3.42e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MILEJKDO_00608	7.67e-63	-	-	-	-	-	-	-	-
MILEJKDO_00609	9.98e-35	-	-	-	-	-	-	-	-
MILEJKDO_00610	1.26e-60	-	-	-	-	-	-	-	-
MILEJKDO_00611	0.0	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_00612	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MILEJKDO_00613	1.65e-301	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MILEJKDO_00614	2.38e-134	-	-	-	V	-	-	-	VanZ like family
MILEJKDO_00615	7.03e-33	-	-	-	-	-	-	-	-
MILEJKDO_00616	4.13e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MILEJKDO_00617	6.26e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MILEJKDO_00618	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
MILEJKDO_00619	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MILEJKDO_00620	3.69e-196	yeaE	-	-	S	-	-	-	Aldo keto
MILEJKDO_00621	3.25e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MILEJKDO_00622	4.03e-211	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MILEJKDO_00623	2.95e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MILEJKDO_00624	1.1e-131	-	-	-	M	-	-	-	LysM domain protein
MILEJKDO_00625	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
MILEJKDO_00626	1.73e-151	-	-	-	M	-	-	-	LysM domain protein
MILEJKDO_00627	7.03e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
MILEJKDO_00628	9.29e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MILEJKDO_00629	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MILEJKDO_00630	1.34e-258	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
MILEJKDO_00631	2.78e-276	isp	-	-	L	-	-	-	Transposase
MILEJKDO_00632	0.0	-	-	-	M	-	-	-	NlpC/P60 family
MILEJKDO_00633	0.0	-	-	-	S	-	-	-	Peptidase, M23
MILEJKDO_00634	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
MILEJKDO_00635	1.3e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00636	9.18e-145	-	-	-	-	-	-	-	-
MILEJKDO_00637	9.48e-183	-	-	-	G	-	-	-	MucBP domain
MILEJKDO_00638	1.75e-127	-	-	-	S	-	-	-	Pfam:DUF3816
MILEJKDO_00639	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MILEJKDO_00640	5.62e-37	-	-	-	-	-	-	-	-
MILEJKDO_00641	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MILEJKDO_00642	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MILEJKDO_00643	2.1e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MILEJKDO_00644	7.98e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MILEJKDO_00645	5.39e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MILEJKDO_00646	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
MILEJKDO_00647	1.37e-48	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
MILEJKDO_00649	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MILEJKDO_00650	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MILEJKDO_00651	1.91e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MILEJKDO_00652	5.98e-55	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
MILEJKDO_00653	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
MILEJKDO_00654	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MILEJKDO_00655	4.65e-195	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MILEJKDO_00656	5.74e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MILEJKDO_00657	1.06e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MILEJKDO_00658	2.05e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MILEJKDO_00659	4.59e-36	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MILEJKDO_00660	3.18e-125	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MILEJKDO_00661	5.22e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MILEJKDO_00662	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
MILEJKDO_00663	1.75e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00664	5.77e-140	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MILEJKDO_00665	2.16e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
MILEJKDO_00666	4.52e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_00667	3.62e-131	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MILEJKDO_00668	1.29e-204	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MILEJKDO_00669	1.02e-61	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MILEJKDO_00670	1.3e-71	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MILEJKDO_00671	1.38e-195	-	-	-	J	-	-	-	Methyltransferase
MILEJKDO_00672	1.87e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MILEJKDO_00673	2.38e-85	-	-	-	L	-	-	-	Transposase
MILEJKDO_00674	1.34e-187	-	-	-	L	-	-	-	Transposase
MILEJKDO_00675	4.7e-282	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
MILEJKDO_00677	2.43e-64	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MILEJKDO_00678	1.77e-198	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
MILEJKDO_00679	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MILEJKDO_00680	2.6e-215	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
MILEJKDO_00681	8.25e-77	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MILEJKDO_00682	2.4e-66	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MILEJKDO_00683	1.16e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MILEJKDO_00684	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MILEJKDO_00686	4.06e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
MILEJKDO_00687	9.72e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MILEJKDO_00688	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MILEJKDO_00689	2.15e-203	-	-	-	EG	-	-	-	EamA-like transporter family
MILEJKDO_00690	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MILEJKDO_00691	3.82e-311	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MILEJKDO_00692	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MILEJKDO_00693	1.56e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MILEJKDO_00694	4.71e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MILEJKDO_00695	8.76e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MILEJKDO_00696	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
MILEJKDO_00697	6.08e-13	-	-	-	S	-	-	-	CsbD-like
MILEJKDO_00698	7.72e-231	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MILEJKDO_00699	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
MILEJKDO_00700	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
MILEJKDO_00701	2.91e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MILEJKDO_00702	3.82e-192	-	-	-	-	-	-	-	-
MILEJKDO_00703	1.83e-33	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
MILEJKDO_00704	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MILEJKDO_00705	9.66e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
MILEJKDO_00706	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
MILEJKDO_00707	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MILEJKDO_00708	1.3e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MILEJKDO_00709	4.14e-295	-	-	-	-	-	-	-	-
MILEJKDO_00710	1.47e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MILEJKDO_00711	3.64e-182	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MILEJKDO_00712	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MILEJKDO_00713	2.94e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MILEJKDO_00714	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MILEJKDO_00715	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MILEJKDO_00716	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MILEJKDO_00717	1.19e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MILEJKDO_00718	8.81e-317	yagE	-	-	E	-	-	-	amino acid
MILEJKDO_00719	3.04e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
MILEJKDO_00720	2.41e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MILEJKDO_00721	2.71e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MILEJKDO_00722	4.47e-177	-	-	-	IQ	-	-	-	KR domain
MILEJKDO_00723	1.03e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MILEJKDO_00724	8.95e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MILEJKDO_00725	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00726	8.69e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MILEJKDO_00727	6.5e-71	-	-	-	-	-	-	-	-
MILEJKDO_00728	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MILEJKDO_00729	1.28e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MILEJKDO_00730	8.47e-240	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MILEJKDO_00731	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_00732	2e-206	-	-	-	-	-	-	-	-
MILEJKDO_00733	7.31e-43	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MILEJKDO_00734	4.45e-81	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MILEJKDO_00735	3.39e-49	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MILEJKDO_00736	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MILEJKDO_00737	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_00738	1.59e-175	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MILEJKDO_00739	7e-153	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
MILEJKDO_00740	3.18e-11	-	-	-	-	-	-	-	-
MILEJKDO_00741	1.78e-83	-	-	-	-	-	-	-	-
MILEJKDO_00742	8.24e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MILEJKDO_00743	4.32e-105	uspA3	-	-	T	-	-	-	universal stress protein
MILEJKDO_00744	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MILEJKDO_00745	1.79e-212	-	-	-	GK	-	-	-	ROK family
MILEJKDO_00746	8.01e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MILEJKDO_00747	9.06e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MILEJKDO_00748	7.11e-309	-	-	-	E	-	-	-	amino acid
MILEJKDO_00749	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MILEJKDO_00750	5.01e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MILEJKDO_00751	2e-114	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MILEJKDO_00752	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MILEJKDO_00753	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MILEJKDO_00754	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00755	1.16e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MILEJKDO_00756	1.7e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MILEJKDO_00757	2.34e-187	-	-	-	-	-	-	-	-
MILEJKDO_00758	1.77e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MILEJKDO_00759	1.87e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
MILEJKDO_00760	6.1e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
MILEJKDO_00761	4.73e-102	yybA	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_00762	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MILEJKDO_00763	1.63e-116	-	-	-	GM	-	-	-	epimerase
MILEJKDO_00764	2.31e-197	-	-	-	V	-	-	-	(ABC) transporter
MILEJKDO_00765	4.1e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
MILEJKDO_00766	4e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MILEJKDO_00767	1.06e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
MILEJKDO_00768	1.7e-242	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
MILEJKDO_00769	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MILEJKDO_00770	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MILEJKDO_00771	4.85e-52	-	-	-	-	-	-	-	-
MILEJKDO_00772	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MILEJKDO_00773	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
MILEJKDO_00774	5.66e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
MILEJKDO_00775	2.14e-296	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MILEJKDO_00776	2.56e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
MILEJKDO_00777	6.6e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MILEJKDO_00778	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MILEJKDO_00779	2.54e-288	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MILEJKDO_00780	3.14e-226	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MILEJKDO_00781	9.06e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MILEJKDO_00782	7.88e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MILEJKDO_00783	1.21e-48	-	-	-	-	-	-	-	-
MILEJKDO_00784	7.19e-68	-	-	-	-	-	-	-	-
MILEJKDO_00785	1.45e-257	-	-	-	-	-	-	-	-
MILEJKDO_00786	5.53e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MILEJKDO_00787	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MILEJKDO_00788	4.18e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
MILEJKDO_00789	1.06e-161	XK27_10500	-	-	K	-	-	-	response regulator
MILEJKDO_00790	2.4e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
MILEJKDO_00791	2.04e-173	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00792	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MILEJKDO_00793	9.11e-198	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MILEJKDO_00794	1.4e-208	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MILEJKDO_00795	2.6e-39	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MILEJKDO_00796	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MILEJKDO_00797	2.85e-250	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_00798	1.6e-117	ymdB	-	-	S	-	-	-	Macro domain protein
MILEJKDO_00799	1.51e-137	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MILEJKDO_00800	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MILEJKDO_00801	1.21e-63	-	-	-	-	-	-	-	-
MILEJKDO_00802	6.86e-294	-	-	-	S	-	-	-	Putative metallopeptidase domain
MILEJKDO_00803	1.33e-257	-	-	-	S	-	-	-	associated with various cellular activities
MILEJKDO_00804	6.7e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MILEJKDO_00805	9.94e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MILEJKDO_00807	7.61e-148	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
MILEJKDO_00808	3.32e-72	-	-	-	-	-	-	-	-
MILEJKDO_00810	3.17e-71	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
MILEJKDO_00811	6.8e-73	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MILEJKDO_00812	2.04e-65	-	-	-	-	-	-	-	-
MILEJKDO_00813	1.39e-257	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
MILEJKDO_00814	1.28e-293	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MILEJKDO_00815	1.24e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MILEJKDO_00816	8.51e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
MILEJKDO_00817	1.35e-87	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MILEJKDO_00818	8.57e-44	-	-	-	S	-	-	-	Putative ABC-transporter type IV
MILEJKDO_00819	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MILEJKDO_00820	6.57e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
MILEJKDO_00821	5.27e-64	-	-	-	-	-	-	-	-
MILEJKDO_00822	2.58e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
MILEJKDO_00823	1.54e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
MILEJKDO_00825	6.29e-170	-	-	-	M	-	-	-	PFAM NLP P60 protein
MILEJKDO_00826	3.69e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MILEJKDO_00827	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MILEJKDO_00828	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00829	7.02e-122	-	-	-	P	-	-	-	Cadmium resistance transporter
MILEJKDO_00830	6.33e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MILEJKDO_00831	2.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MILEJKDO_00832	4.41e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
MILEJKDO_00833	1.95e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MILEJKDO_00834	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MILEJKDO_00835	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MILEJKDO_00836	2.37e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MILEJKDO_00837	8.86e-317	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MILEJKDO_00838	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MILEJKDO_00839	9.13e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
MILEJKDO_00840	1.4e-53	-	-	-	-	-	-	-	-
MILEJKDO_00841	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MILEJKDO_00842	3.46e-265	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
MILEJKDO_00843	1.87e-176	-	-	-	S	-	-	-	Alpha beta hydrolase
MILEJKDO_00844	8.39e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MILEJKDO_00845	3.08e-128	-	-	-	-	-	-	-	-
MILEJKDO_00847	2.72e-157	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MILEJKDO_00848	2.61e-19	-	-	-	-	-	-	-	-
MILEJKDO_00849	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MILEJKDO_00850	2.91e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MILEJKDO_00851	8.57e-114	-	-	-	-	-	-	-	-
MILEJKDO_00852	5.38e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MILEJKDO_00853	1.23e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_00854	2.43e-145	-	-	-	-	-	-	-	-
MILEJKDO_00855	2.6e-33	-	-	-	-	-	-	-	-
MILEJKDO_00856	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MILEJKDO_00857	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MILEJKDO_00858	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MILEJKDO_00859	3.96e-49	-	-	-	-	-	-	-	-
MILEJKDO_00860	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00861	8.51e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00862	7.99e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MILEJKDO_00863	1.07e-112	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
MILEJKDO_00864	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
MILEJKDO_00865	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MILEJKDO_00866	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MILEJKDO_00868	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MILEJKDO_00869	1.09e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MILEJKDO_00870	5.85e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
MILEJKDO_00871	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
MILEJKDO_00872	5.16e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MILEJKDO_00873	1.99e-73	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MILEJKDO_00874	4.81e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MILEJKDO_00875	2.72e-174	-	-	-	S	-	-	-	DUF218 domain
MILEJKDO_00876	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
MILEJKDO_00877	2.75e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
MILEJKDO_00878	9.74e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
MILEJKDO_00879	9.25e-306	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MILEJKDO_00880	6.68e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
MILEJKDO_00881	1.06e-104	-	-	-	S	-	-	-	Cupin domain
MILEJKDO_00882	3.22e-128	epsB	-	-	M	-	-	-	biosynthesis protein
MILEJKDO_00883	2.47e-139	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MILEJKDO_00884	2.19e-60	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
MILEJKDO_00885	3.03e-104	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
MILEJKDO_00886	1.18e-81	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
MILEJKDO_00887	2.24e-49	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
MILEJKDO_00889	1.99e-85	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MILEJKDO_00890	2.85e-33	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MILEJKDO_00891	9.59e-36	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
MILEJKDO_00892	8.23e-32	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
MILEJKDO_00893	5.72e-55	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MILEJKDO_00896	5.17e-32	-	-	-	S	-	-	-	Acyltransferase family
MILEJKDO_00897	1.72e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MILEJKDO_00898	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
MILEJKDO_00899	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
MILEJKDO_00900	4.68e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MILEJKDO_00901	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MILEJKDO_00902	1.07e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MILEJKDO_00903	1.44e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
MILEJKDO_00904	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MILEJKDO_00905	7.76e-195	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MILEJKDO_00906	3.99e-127	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MILEJKDO_00907	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MILEJKDO_00908	2.08e-302	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
MILEJKDO_00909	7.06e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MILEJKDO_00910	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MILEJKDO_00911	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MILEJKDO_00912	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MILEJKDO_00914	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MILEJKDO_00915	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MILEJKDO_00916	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MILEJKDO_00917	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MILEJKDO_00918	8.15e-109	-	-	-	-	-	-	-	-
MILEJKDO_00919	7.43e-45	-	-	-	-	-	-	-	-
MILEJKDO_00920	1.42e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MILEJKDO_00921	1.05e-165	-	-	-	-	-	-	-	-
MILEJKDO_00922	3.78e-88	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MILEJKDO_00923	2.07e-218	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MILEJKDO_00924	2.6e-182	epsB	-	-	M	-	-	-	biosynthesis protein
MILEJKDO_00925	9.25e-152	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MILEJKDO_00926	1.31e-136	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
MILEJKDO_00927	4.12e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MILEJKDO_00928	1.62e-263	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MILEJKDO_00929	1.72e-94	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MILEJKDO_00930	1.23e-107	-	-	-	-	-	-	-	-
MILEJKDO_00931	2.89e-36	-	-	-	M	-	-	-	biosynthesis protein
MILEJKDO_00932	7.78e-96	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
MILEJKDO_00933	7.27e-83	-	-	-	S	-	-	-	Glycosyltransferase like family
MILEJKDO_00934	2.31e-96	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
MILEJKDO_00935	1e-90	-	-	-	S	-	-	-	Acyltransferase family
MILEJKDO_00936	2.58e-94	-	-	-	-	-	-	-	-
MILEJKDO_00937	5.29e-86	-	-	-	M	-	-	-	Glycosyl transferase family 2
MILEJKDO_00938	6.77e-61	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MILEJKDO_00939	5.94e-278	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
MILEJKDO_00940	2.85e-45	-	-	-	S	-	-	-	Glycosyl transferase family 2
MILEJKDO_00941	1.22e-33	-	-	-	-	-	-	-	-
MILEJKDO_00942	3.04e-89	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MILEJKDO_00943	3.95e-127	lpg2	2.4.1.337	GT4	M	ko:K00754,ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	transferase activity, transferring glycosyl groups
MILEJKDO_00944	7.67e-179	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MILEJKDO_00945	4.6e-91	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
MILEJKDO_00946	2.03e-156	-	-	-	G	-	-	-	Glycosyltransferase Family 4
MILEJKDO_00947	7.72e-184	wchF	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
MILEJKDO_00948	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MILEJKDO_00950	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MILEJKDO_00951	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MILEJKDO_00952	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_00953	1.24e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MILEJKDO_00954	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
MILEJKDO_00955	2.37e-218	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MILEJKDO_00956	4.03e-206	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MILEJKDO_00957	9.71e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MILEJKDO_00958	6.46e-201	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MILEJKDO_00959	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MILEJKDO_00960	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MILEJKDO_00961	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MILEJKDO_00962	5.01e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MILEJKDO_00963	1.81e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MILEJKDO_00964	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MILEJKDO_00965	1.97e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MILEJKDO_00966	8.18e-303	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
MILEJKDO_00967	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MILEJKDO_00968	2.18e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
MILEJKDO_00969	2.84e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MILEJKDO_00970	9.76e-161	vanR	-	-	K	-	-	-	response regulator
MILEJKDO_00971	6.19e-263	hpk31	-	-	T	-	-	-	Histidine kinase
MILEJKDO_00972	3.97e-185	-	-	-	E	-	-	-	AzlC protein
MILEJKDO_00973	9.94e-71	-	-	-	S	-	-	-	branched-chain amino acid
MILEJKDO_00974	1.53e-39	-	-	-	K	-	-	-	LysR substrate binding domain
MILEJKDO_00975	3.12e-105	-	-	-	K	-	-	-	LysR substrate binding domain
MILEJKDO_00976	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MILEJKDO_00977	6.82e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MILEJKDO_00978	1.6e-219	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MILEJKDO_00979	7.97e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MILEJKDO_00980	5.26e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MILEJKDO_00981	2.61e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MILEJKDO_00982	9.49e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MILEJKDO_00983	1.94e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
MILEJKDO_00984	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MILEJKDO_00985	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MILEJKDO_00986	4.79e-161	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
MILEJKDO_00987	1.26e-232	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MILEJKDO_00988	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MILEJKDO_00989	4.28e-128	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MILEJKDO_00990	7.36e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MILEJKDO_00991	9.04e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MILEJKDO_00992	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MILEJKDO_00993	1.75e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MILEJKDO_00994	6.16e-48	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MILEJKDO_00995	1.9e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MILEJKDO_00996	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MILEJKDO_00997	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MILEJKDO_00998	7.51e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MILEJKDO_00999	4.78e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MILEJKDO_01000	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MILEJKDO_01001	2.76e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MILEJKDO_01002	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MILEJKDO_01003	1.94e-227	-	-	-	-	-	-	-	-
MILEJKDO_01004	5.99e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MILEJKDO_01005	1.56e-254	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_01007	9.82e-92	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MILEJKDO_01008	9.21e-99	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MILEJKDO_01009	3.33e-126	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MILEJKDO_01010	6.46e-66	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MILEJKDO_01011	1.24e-42	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MILEJKDO_01012	5.03e-190	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MILEJKDO_01013	9.08e-153	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MILEJKDO_01014	7.84e-71	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MILEJKDO_01015	3.61e-60	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MILEJKDO_01016	1.94e-134	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MILEJKDO_01017	2.7e-70	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MILEJKDO_01018	2.11e-174	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MILEJKDO_01019	9.22e-74	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MILEJKDO_01033	4.11e-223	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MILEJKDO_01034	1.46e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MILEJKDO_01035	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MILEJKDO_01036	2.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
MILEJKDO_01037	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MILEJKDO_01038	5.93e-265	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MILEJKDO_01039	9.02e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MILEJKDO_01040	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MILEJKDO_01041	3.75e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MILEJKDO_01042	2.64e-282	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MILEJKDO_01043	1.03e-148	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
MILEJKDO_01044	2.22e-275	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MILEJKDO_01045	1.76e-128	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MILEJKDO_01046	1.33e-125	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MILEJKDO_01047	1.56e-76	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MILEJKDO_01048	3.81e-110	-	-	-	-	-	-	-	-
MILEJKDO_01049	2.17e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MILEJKDO_01050	2.58e-71	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
MILEJKDO_01051	6.8e-46	-	-	-	-	-	-	-	-
MILEJKDO_01052	1.05e-194	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MILEJKDO_01053	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
MILEJKDO_01054	5.31e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
MILEJKDO_01055	2.18e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MILEJKDO_01056	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MILEJKDO_01057	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
MILEJKDO_01058	2.21e-226	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MILEJKDO_01059	1.52e-267	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MILEJKDO_01060	4.41e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MILEJKDO_01061	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MILEJKDO_01062	1.49e-229	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
MILEJKDO_01063	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MILEJKDO_01064	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MILEJKDO_01065	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MILEJKDO_01066	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
MILEJKDO_01067	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
MILEJKDO_01068	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MILEJKDO_01069	3.91e-91	-	-	-	-	-	-	-	-
MILEJKDO_01070	5.01e-33	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
MILEJKDO_01071	6.23e-94	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MILEJKDO_01072	2.58e-139	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
MILEJKDO_01073	1.58e-314	-	-	-	E	-	-	-	amino acid
MILEJKDO_01074	8.02e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MILEJKDO_01076	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MILEJKDO_01077	1.47e-120	-	-	-	-	-	-	-	-
MILEJKDO_01078	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MILEJKDO_01079	4.32e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MILEJKDO_01080	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
MILEJKDO_01081	3.1e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MILEJKDO_01082	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MILEJKDO_01083	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
MILEJKDO_01084	1.8e-215	-	-	-	C	-	-	-	Aldo keto reductase
MILEJKDO_01085	3.7e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MILEJKDO_01086	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MILEJKDO_01087	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MILEJKDO_01088	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MILEJKDO_01089	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MILEJKDO_01090	7.05e-270	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MILEJKDO_01091	3e-221	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MILEJKDO_01092	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MILEJKDO_01093	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MILEJKDO_01094	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MILEJKDO_01095	4.76e-137	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
MILEJKDO_01097	2.53e-209	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MILEJKDO_01098	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
MILEJKDO_01099	8.68e-44	-	-	-	-	-	-	-	-
MILEJKDO_01100	9.3e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MILEJKDO_01101	2.78e-227	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MILEJKDO_01102	9.74e-98	-	-	-	O	-	-	-	OsmC-like protein
MILEJKDO_01104	2.3e-308	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MILEJKDO_01108	3.52e-176	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MILEJKDO_01109	4.51e-182	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MILEJKDO_01113	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MILEJKDO_01114	7.07e-65	-	-	-	-	-	-	-	-
MILEJKDO_01116	8.65e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MILEJKDO_01117	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MILEJKDO_01118	2.03e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MILEJKDO_01119	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MILEJKDO_01120	2.05e-187	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MILEJKDO_01121	5.08e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
MILEJKDO_01122	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MILEJKDO_01123	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
MILEJKDO_01124	1.1e-125	-	-	-	S	-	-	-	reductase
MILEJKDO_01125	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MILEJKDO_01126	2.08e-26	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MILEJKDO_01127	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
MILEJKDO_01128	2.46e-289	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MILEJKDO_01129	1.46e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MILEJKDO_01130	7.14e-193	yycI	-	-	S	-	-	-	YycH protein
MILEJKDO_01131	8.68e-316	yycH	-	-	S	-	-	-	YycH protein
MILEJKDO_01132	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MILEJKDO_01133	2.6e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MILEJKDO_01135	4.87e-207	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MILEJKDO_01136	5.25e-57	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MILEJKDO_01137	9.31e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
MILEJKDO_01139	1.38e-158	-	-	-	S	-	-	-	Fic/DOC family
MILEJKDO_01140	3.08e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
MILEJKDO_01141	1.57e-71	-	-	-	-	-	-	-	-
MILEJKDO_01142	8.85e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_01143	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MILEJKDO_01144	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MILEJKDO_01145	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MILEJKDO_01146	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MILEJKDO_01147	8.08e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MILEJKDO_01148	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MILEJKDO_01149	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MILEJKDO_01150	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MILEJKDO_01151	3.44e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MILEJKDO_01152	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MILEJKDO_01153	9.9e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MILEJKDO_01154	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MILEJKDO_01155	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MILEJKDO_01156	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MILEJKDO_01157	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MILEJKDO_01159	7.1e-264	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MILEJKDO_01160	3.38e-60	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
MILEJKDO_01161	2.05e-169	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_01162	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MILEJKDO_01164	9.9e-56	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
MILEJKDO_01167	7.62e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
MILEJKDO_01168	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MILEJKDO_01169	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MILEJKDO_01170	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MILEJKDO_01171	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MILEJKDO_01172	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MILEJKDO_01173	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MILEJKDO_01174	9.23e-116	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
MILEJKDO_01175	9.53e-206	-	-	-	S	-	-	-	reductase
MILEJKDO_01177	1.57e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MILEJKDO_01178	0.000336	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MILEJKDO_01179	1.18e-45	-	-	-	K	-	-	-	LysR substrate binding domain
MILEJKDO_01181	1.04e-24	-	-	-	S	-	-	-	amidohydrolase
MILEJKDO_01182	4.27e-291	-	-	-	S	-	-	-	amidohydrolase
MILEJKDO_01184	1.91e-42	blpT	-	-	-	-	-	-	-
MILEJKDO_01185	1.08e-53	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MILEJKDO_01186	1.28e-11	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MILEJKDO_01187	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
MILEJKDO_01188	1.75e-29	-	-	-	-	-	-	-	-
MILEJKDO_01189	3.09e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MILEJKDO_01190	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
MILEJKDO_01191	6.49e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MILEJKDO_01192	4.12e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
MILEJKDO_01193	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MILEJKDO_01194	1.34e-199	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MILEJKDO_01195	1.54e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MILEJKDO_01196	4.77e-65	yrvD	-	-	S	-	-	-	Pfam:DUF1049
MILEJKDO_01198	3.64e-175	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_01199	6.74e-119	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
MILEJKDO_01201	1.87e-74	-	-	-	S	-	-	-	Pfam:DUF59
MILEJKDO_01202	2.37e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MILEJKDO_01203	1.17e-21	-	-	-	K	-	-	-	Transcriptional regulator, LacI family
MILEJKDO_01204	4.1e-111	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MILEJKDO_01205	5.86e-118	-	-	-	L	-	-	-	Integrase
MILEJKDO_01206	4.8e-19	XK27_09155	-	-	K	-	-	-	Transcriptional
MILEJKDO_01207	1.36e-80	-	-	-	M	-	-	-	Glycosyl transferase family 2
MILEJKDO_01208	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MILEJKDO_01210	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MILEJKDO_01211	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MILEJKDO_01212	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MILEJKDO_01213	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
MILEJKDO_01215	1.45e-225	-	-	-	M	-	-	-	Glycosyl transferase family group 2
MILEJKDO_01216	4.04e-264	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MILEJKDO_01217	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MILEJKDO_01218	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MILEJKDO_01219	1.68e-64	-	-	-	-	-	-	-	-
MILEJKDO_01221	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MILEJKDO_01222	9.71e-76	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
MILEJKDO_01223	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
MILEJKDO_01224	1.49e-175	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
MILEJKDO_01225	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MILEJKDO_01226	3.81e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MILEJKDO_01227	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MILEJKDO_01228	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MILEJKDO_01229	7.25e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MILEJKDO_01230	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MILEJKDO_01231	6.86e-61	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MILEJKDO_01232	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MILEJKDO_01233	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MILEJKDO_01234	6.4e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MILEJKDO_01235	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MILEJKDO_01236	3.7e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MILEJKDO_01237	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MILEJKDO_01238	3.17e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MILEJKDO_01239	1.28e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MILEJKDO_01240	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MILEJKDO_01241	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MILEJKDO_01242	6.8e-224	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MILEJKDO_01243	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MILEJKDO_01244	1.22e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MILEJKDO_01245	4.12e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MILEJKDO_01246	5.83e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MILEJKDO_01247	1.26e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MILEJKDO_01248	8.21e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MILEJKDO_01249	2.2e-178	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MILEJKDO_01250	9e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MILEJKDO_01251	4.39e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MILEJKDO_01252	6.9e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MILEJKDO_01253	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MILEJKDO_01254	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MILEJKDO_01255	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MILEJKDO_01256	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MILEJKDO_01257	6.02e-104	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
MILEJKDO_01258	0.0	-	-	-	E	-	-	-	amino acid
MILEJKDO_01259	0.0	ydaO	-	-	E	-	-	-	amino acid
MILEJKDO_01260	1.78e-51	-	-	-	-	-	-	-	-
MILEJKDO_01261	4.03e-85	-	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_01262	5.74e-31	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_01263	1.33e-110	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_01264	3.26e-95	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_01265	1.91e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MILEJKDO_01266	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MILEJKDO_01267	4.87e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MILEJKDO_01268	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MILEJKDO_01269	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MILEJKDO_01270	1.11e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MILEJKDO_01271	2.47e-65	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MILEJKDO_01272	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MILEJKDO_01273	2.29e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MILEJKDO_01274	3.18e-198	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MILEJKDO_01275	2.31e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MILEJKDO_01276	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MILEJKDO_01277	3.55e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
MILEJKDO_01278	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
MILEJKDO_01279	1.2e-200	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
MILEJKDO_01280	3.37e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MILEJKDO_01281	7.51e-265	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MILEJKDO_01282	2.96e-208	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
MILEJKDO_01283	6.99e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
MILEJKDO_01284	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MILEJKDO_01285	3.55e-147	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
MILEJKDO_01286	4e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MILEJKDO_01288	2.08e-88	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	transcriptional regulator containing an HTH domain and an
MILEJKDO_01289	1.52e-114	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MILEJKDO_01290	9.26e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MILEJKDO_01291	7.12e-171	-	-	-	O	-	-	-	Bacterial dnaA protein
MILEJKDO_01292	2.72e-303	-	-	-	L	-	-	-	Integrase core domain
MILEJKDO_01295	3.75e-77	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MILEJKDO_01296	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
MILEJKDO_01297	7.76e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MILEJKDO_01298	2.96e-116	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MILEJKDO_01299	4.38e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MILEJKDO_01300	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MILEJKDO_01301	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MILEJKDO_01302	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MILEJKDO_01303	2e-283	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MILEJKDO_01304	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MILEJKDO_01305	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MILEJKDO_01306	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MILEJKDO_01307	8.38e-235	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MILEJKDO_01308	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MILEJKDO_01309	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MILEJKDO_01310	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MILEJKDO_01311	3.15e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MILEJKDO_01312	8.12e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MILEJKDO_01313	1.5e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MILEJKDO_01314	1.03e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MILEJKDO_01315	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MILEJKDO_01316	3.5e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MILEJKDO_01317	1.63e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MILEJKDO_01318	4.98e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MILEJKDO_01319	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MILEJKDO_01320	1.17e-268	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MILEJKDO_01321	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MILEJKDO_01322	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MILEJKDO_01323	7.4e-71	-	-	-	-	-	-	-	-
MILEJKDO_01324	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MILEJKDO_01325	2.25e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MILEJKDO_01326	1.97e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MILEJKDO_01327	3.54e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MILEJKDO_01328	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MILEJKDO_01329	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MILEJKDO_01330	6.56e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MILEJKDO_01331	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MILEJKDO_01332	1.32e-92	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MILEJKDO_01333	4.37e-141	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
MILEJKDO_01334	1.18e-253	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MILEJKDO_01335	4.82e-164	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MILEJKDO_01336	7.2e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MILEJKDO_01337	5.08e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MILEJKDO_01338	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MILEJKDO_01339	5.7e-146	-	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_01342	1.36e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
MILEJKDO_01343	2.09e-223	-	-	-	-	-	-	-	-
MILEJKDO_01344	4e-202	-	-	-	-	-	-	-	-
MILEJKDO_01345	4.41e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MILEJKDO_01346	9.48e-130	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MILEJKDO_01347	1.54e-97	-	-	-	S	-	-	-	Fic/DOC family
MILEJKDO_01348	7.06e-64	-	-	-	E	-	-	-	Filamentation induced by cAMP protein fic
MILEJKDO_01355	6.21e-31	-	-	-	S	-	-	-	Peptidase family M23
MILEJKDO_01357	1.04e-238	-	-	-	U	-	-	-	type IV secretory pathway VirB4
MILEJKDO_01358	4.26e-35	-	-	-	-	-	-	-	-
MILEJKDO_01360	5.9e-74	-	-	-	-	-	-	-	-
MILEJKDO_01361	1.02e-277	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
MILEJKDO_01366	1.52e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MILEJKDO_01369	5.01e-172	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
MILEJKDO_01370	7.99e-61	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
MILEJKDO_01371	8.54e-13	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MILEJKDO_01374	6.33e-19	-	-	-	K	-	-	-	ORF6N domain
MILEJKDO_01375	1.51e-34	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
MILEJKDO_01378	1.88e-115	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_01379	1.03e-55	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MILEJKDO_01380	7.49e-283	-	-	-	V	-	-	-	N-6 DNA Methylase
MILEJKDO_01389	1.33e-76	-	-	-	-	-	-	-	-
MILEJKDO_01391	1.19e-13	-	-	-	T	-	-	-	SpoVT / AbrB like domain
MILEJKDO_01392	2.08e-30	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MILEJKDO_01393	2.52e-22	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
MILEJKDO_01394	1.48e-26	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MILEJKDO_01398	4.17e-68	-	-	-	L	-	-	-	four-way junction helicase activity
MILEJKDO_01410	1.11e-21	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
MILEJKDO_01423	5.5e-05	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
MILEJKDO_01427	1.28e-33	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MILEJKDO_01430	6.49e-13	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MILEJKDO_01433	1.14e-07	-	-	-	K	-	-	-	Peptidase S24-like
MILEJKDO_01435	1.29e-93	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_01437	5.34e-22	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
MILEJKDO_01438	4.29e-179	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MILEJKDO_01439	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
MILEJKDO_01440	4.32e-08	comA	-	-	V	ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MILEJKDO_01443	9.19e-88	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_01444	3.38e-27	-	-	-	L	-	-	-	Integrase core domain
MILEJKDO_01445	3.48e-279	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MILEJKDO_01446	4.29e-74	-	-	-	-	-	-	-	-
MILEJKDO_01447	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MILEJKDO_01449	1.79e-42	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MILEJKDO_01450	2.16e-28	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MILEJKDO_01451	9.84e-132	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
MILEJKDO_01452	1.58e-310	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
MILEJKDO_01453	9.89e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
MILEJKDO_01454	4.68e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MILEJKDO_01456	1.45e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MILEJKDO_01457	1.29e-53	-	-	-	S	-	-	-	Cytochrome B5
MILEJKDO_01458	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
MILEJKDO_01459	9.37e-52	-	-	-	S	-	-	-	Cytochrome B5
MILEJKDO_01460	1.99e-50	-	-	-	S	ko:K02348	-	ko00000	Gnat family
MILEJKDO_01461	6.12e-11	-	-	-	S	ko:K02348	-	ko00000	Gnat family
MILEJKDO_01462	2e-14	-	-	-	GM	-	-	-	NmrA-like family
MILEJKDO_01463	4.55e-68	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MILEJKDO_01464	1.3e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MILEJKDO_01465	2.25e-100	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MILEJKDO_01466	2.18e-289	-	-	-	-	-	-	-	-
MILEJKDO_01467	1.32e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MILEJKDO_01468	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
MILEJKDO_01469	1.97e-143	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
MILEJKDO_01470	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MILEJKDO_01471	9.85e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MILEJKDO_01472	2.72e-38	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MILEJKDO_01473	3.51e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MILEJKDO_01474	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MILEJKDO_01476	4.89e-167	-	-	-	F	-	-	-	glutamine amidotransferase
MILEJKDO_01477	1.61e-81	-	-	-	-	-	-	-	-
MILEJKDO_01478	1.29e-201	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
MILEJKDO_01479	2.39e-196	-	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_01480	4.68e-234	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
MILEJKDO_01481	6.71e-220	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MILEJKDO_01482	3.15e-115	-	-	-	K	-	-	-	Virulence activator alpha C-term
MILEJKDO_01483	4.68e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MILEJKDO_01484	6.18e-51	-	-	-	C	-	-	-	Flavodoxin
MILEJKDO_01485	8.91e-146	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
MILEJKDO_01486	5.58e-70	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MILEJKDO_01487	1.94e-13	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MILEJKDO_01488	3.15e-141	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
MILEJKDO_01489	1.32e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MILEJKDO_01490	4.25e-306	-	-	-	T	-	-	-	GHKL domain
MILEJKDO_01491	3.03e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MILEJKDO_01492	9.98e-56	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MILEJKDO_01494	1.45e-10	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
MILEJKDO_01497	6.41e-163	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
MILEJKDO_01498	5.09e-153	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
MILEJKDO_01499	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MILEJKDO_01500	9.98e-24	-	-	-	-	-	-	-	-
MILEJKDO_01501	3.56e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
MILEJKDO_01502	6.28e-116	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MILEJKDO_01503	1.03e-96	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MILEJKDO_01504	9.27e-245	flp	-	-	V	-	-	-	Beta-lactamase
MILEJKDO_01505	4.83e-118	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MILEJKDO_01506	2.21e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
MILEJKDO_01507	4.04e-87	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MILEJKDO_01508	1.13e-40	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
MILEJKDO_01510	8.34e-147	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MILEJKDO_01511	2.43e-142	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
MILEJKDO_01513	1.04e-170	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MILEJKDO_01514	1.8e-127	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MILEJKDO_01515	6.56e-223	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MILEJKDO_01516	3.7e-72	-	-	-	-	-	-	-	-
MILEJKDO_01517	8.83e-160	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MILEJKDO_01518	1.57e-46	-	-	-	-	-	-	-	-
MILEJKDO_01519	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
MILEJKDO_01520	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
MILEJKDO_01521	3.3e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
MILEJKDO_01522	1.09e-222	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MILEJKDO_01523	3.17e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MILEJKDO_01524	2.02e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MILEJKDO_01525	7.27e-42	-	-	-	-	-	-	-	-
MILEJKDO_01526	8.54e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MILEJKDO_01527	1.83e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MILEJKDO_01528	0.0	potE	-	-	E	-	-	-	Amino Acid
MILEJKDO_01529	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MILEJKDO_01530	1.39e-280	arcT	-	-	E	-	-	-	Aminotransferase
MILEJKDO_01531	1.42e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MILEJKDO_01532	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MILEJKDO_01533	1.73e-97	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MILEJKDO_01534	1e-72	-	-	-	-	-	-	-	-
MILEJKDO_01535	4.92e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MILEJKDO_01537	1.91e-297	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MILEJKDO_01538	1.03e-242	mocA	-	-	S	-	-	-	Oxidoreductase
MILEJKDO_01539	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
MILEJKDO_01540	6.95e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MILEJKDO_01541	1.25e-211	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MILEJKDO_01542	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MILEJKDO_01543	1.64e-242	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
MILEJKDO_01544	4.19e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
MILEJKDO_01545	9.21e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MILEJKDO_01546	1.7e-26	-	-	-	-	-	-	-	-
MILEJKDO_01547	2.2e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
MILEJKDO_01548	1.16e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MILEJKDO_01549	1.28e-186	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
MILEJKDO_01550	1.18e-24	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MILEJKDO_01551	7.86e-34	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
MILEJKDO_01552	2.6e-150	pnb	-	-	C	-	-	-	nitroreductase
MILEJKDO_01553	1.23e-49	-	-	-	-	-	-	-	-
MILEJKDO_01554	8.93e-307	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
MILEJKDO_01555	2.93e-112	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MILEJKDO_01557	6.57e-63	-	-	-	-	-	-	-	-
MILEJKDO_01558	4.16e-198	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MILEJKDO_01559	8.27e-189	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MILEJKDO_01560	8.81e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
MILEJKDO_01561	4.65e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MILEJKDO_01563	1.04e-222	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MILEJKDO_01564	3.5e-91	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MILEJKDO_01565	1.62e-67	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MILEJKDO_01566	1.67e-58	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_01567	5.19e-35	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_01568	5.67e-70	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MILEJKDO_01569	3.78e-23	-	-	-	-	-	-	-	-
MILEJKDO_01570	6.13e-27	-	-	-	-	-	-	-	-
MILEJKDO_01571	1.56e-31	-	-	-	-	-	-	-	-
MILEJKDO_01572	6.9e-25	-	-	-	K	-	-	-	LytTr DNA-binding domain
MILEJKDO_01573	5.04e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
MILEJKDO_01574	1.84e-104	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MILEJKDO_01575	4.11e-85	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MILEJKDO_01577	1.61e-75	-	-	-	-	-	-	-	-
MILEJKDO_01578	2.23e-94	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MILEJKDO_01579	4.45e-67	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MILEJKDO_01580	1.99e-66	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
MILEJKDO_01581	1.5e-243	-	-	-	L	-	-	-	Transposase
MILEJKDO_01582	1.56e-96	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
MILEJKDO_01583	4.43e-43	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
MILEJKDO_01584	5.16e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
MILEJKDO_01585	8e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
MILEJKDO_01586	1.09e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
MILEJKDO_01587	7.25e-44	-	-	-	C	-	-	-	Heavy-metal-associated domain
MILEJKDO_01588	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
MILEJKDO_01589	1.76e-133	-	-	-	-	-	-	-	-
MILEJKDO_01590	2.46e-137	-	-	-	L	-	-	-	Bacterial dnaA protein
MILEJKDO_01592	9.41e-222	-	-	-	L	-	-	-	Integrase core domain
MILEJKDO_01593	3.38e-27	-	-	-	L	-	-	-	Integrase core domain
MILEJKDO_01594	2.95e-50	-	-	-	K	-	-	-	NAD+ binding
MILEJKDO_01595	8.39e-217	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MILEJKDO_01596	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MILEJKDO_01597	1.46e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MILEJKDO_01598	1.66e-97	-	-	-	L	-	-	-	ATPase involved in DNA repair
MILEJKDO_01600	2.7e-37	-	-	-	-	-	-	-	-
MILEJKDO_01602	2.01e-35	-	-	-	-	-	-	-	-
MILEJKDO_01603	1.18e-27	-	-	-	-	-	-	-	-
MILEJKDO_01604	6.6e-15	-	-	-	S	-	-	-	Phage-related holin (Lysis protein)
MILEJKDO_01605	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MILEJKDO_01606	1.64e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MILEJKDO_01607	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MILEJKDO_01608	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MILEJKDO_01609	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MILEJKDO_01610	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
MILEJKDO_01611	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MILEJKDO_01612	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MILEJKDO_01613	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MILEJKDO_01614	2.36e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MILEJKDO_01615	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MILEJKDO_01616	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MILEJKDO_01617	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MILEJKDO_01618	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MILEJKDO_01619	4.31e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MILEJKDO_01620	8.27e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MILEJKDO_01621	6.13e-198	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MILEJKDO_01622	2.47e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MILEJKDO_01623	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MILEJKDO_01624	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MILEJKDO_01625	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MILEJKDO_01626	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MILEJKDO_01627	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MILEJKDO_01628	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MILEJKDO_01629	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MILEJKDO_01630	1.66e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MILEJKDO_01631	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MILEJKDO_01632	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MILEJKDO_01633	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MILEJKDO_01634	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MILEJKDO_01635	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MILEJKDO_01636	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MILEJKDO_01637	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MILEJKDO_01638	5.22e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MILEJKDO_01639	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MILEJKDO_01640	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MILEJKDO_01641	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MILEJKDO_01642	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MILEJKDO_01643	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MILEJKDO_01644	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MILEJKDO_01645	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MILEJKDO_01646	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MILEJKDO_01647	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MILEJKDO_01648	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MILEJKDO_01649	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MILEJKDO_01650	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MILEJKDO_01651	3.32e-206	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MILEJKDO_01652	4.41e-124	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MILEJKDO_01653	1.58e-110	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
MILEJKDO_01654	2.98e-252	-	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_01655	4.38e-175	-	-	-	M	-	-	-	Lysin motif
MILEJKDO_01656	1.63e-104	-	-	-	-	-	-	-	-
MILEJKDO_01657	1.54e-217	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MILEJKDO_01658	7.23e-124	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
MILEJKDO_01659	3.69e-203	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MILEJKDO_01660	3.7e-19	-	-	-	-	-	-	-	-
MILEJKDO_01661	4.44e-117	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MILEJKDO_01662	6.29e-250	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MILEJKDO_01663	1.71e-144	-	-	-	S	-	-	-	Membrane
MILEJKDO_01664	1.1e-161	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
MILEJKDO_01665	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MILEJKDO_01666	1.3e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MILEJKDO_01668	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MILEJKDO_01669	9.57e-106	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MILEJKDO_01670	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MILEJKDO_01671	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MILEJKDO_01672	3.47e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MILEJKDO_01673	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MILEJKDO_01674	4.8e-221	-	-	-	-	-	-	-	-
MILEJKDO_01676	4.98e-32	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MILEJKDO_01677	2.68e-30	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MILEJKDO_01678	2.23e-124	-	-	-	K	-	-	-	acetyltransferase
MILEJKDO_01679	6.33e-28	-	-	-	-	-	-	-	-
MILEJKDO_01680	5.55e-41	-	-	-	-	-	-	-	-
MILEJKDO_01681	6.97e-40	-	-	-	-	-	-	-	-
MILEJKDO_01682	4.05e-147	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MILEJKDO_01685	2.47e-250	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MILEJKDO_01686	4.11e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MILEJKDO_01687	0.0	-	-	-	L	-	-	-	DNA helicase
MILEJKDO_01688	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
MILEJKDO_01689	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
MILEJKDO_01690	9.18e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MILEJKDO_01691	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MILEJKDO_01692	5.82e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MILEJKDO_01693	1.89e-228	-	-	-	-	-	-	-	-
MILEJKDO_01694	3.28e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MILEJKDO_01696	9.56e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
MILEJKDO_01697	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MILEJKDO_01698	3.73e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MILEJKDO_01699	8.57e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MILEJKDO_01700	6.45e-209	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MILEJKDO_01701	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MILEJKDO_01702	6.98e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MILEJKDO_01703	3.48e-216	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MILEJKDO_01704	9.8e-158	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MILEJKDO_01705	3.54e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MILEJKDO_01706	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MILEJKDO_01707	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MILEJKDO_01708	9.36e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MILEJKDO_01709	2.58e-102	-	-	-	-	-	-	-	-
MILEJKDO_01710	4.65e-190	yidA	-	-	S	-	-	-	hydrolase
MILEJKDO_01711	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
MILEJKDO_01712	9.72e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
MILEJKDO_01713	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MILEJKDO_01714	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MILEJKDO_01715	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MILEJKDO_01716	1.58e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MILEJKDO_01717	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MILEJKDO_01718	2.26e-303	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MILEJKDO_01719	2.26e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MILEJKDO_01720	1.01e-160	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MILEJKDO_01721	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MILEJKDO_01722	9.19e-193	-	-	-	G	-	-	-	Right handed beta helix region
MILEJKDO_01723	2.37e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MILEJKDO_01724	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MILEJKDO_01725	4.33e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
MILEJKDO_01726	1.15e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MILEJKDO_01727	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MILEJKDO_01728	4.32e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MILEJKDO_01729	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MILEJKDO_01730	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MILEJKDO_01731	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
MILEJKDO_01732	5.99e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MILEJKDO_01733	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MILEJKDO_01734	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MILEJKDO_01735	9.07e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MILEJKDO_01736	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MILEJKDO_01737	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MILEJKDO_01738	1.61e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MILEJKDO_01739	2.55e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MILEJKDO_01740	2.17e-81	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MILEJKDO_01741	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MILEJKDO_01742	5.33e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
MILEJKDO_01743	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
MILEJKDO_01744	1.9e-145	-	-	-	S	-	-	-	(CBS) domain
MILEJKDO_01745	5.62e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MILEJKDO_01746	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MILEJKDO_01747	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
MILEJKDO_01748	1.23e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MILEJKDO_01749	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
MILEJKDO_01750	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MILEJKDO_01751	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MILEJKDO_01752	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MILEJKDO_01753	9.26e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MILEJKDO_01754	3.59e-240	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MILEJKDO_01755	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MILEJKDO_01756	4.1e-67	entB	-	-	Q	-	-	-	Isochorismatase family
MILEJKDO_01757	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
MILEJKDO_01758	6.78e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
MILEJKDO_01759	2e-70	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MILEJKDO_01760	4.99e-128	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MILEJKDO_01761	1.39e-33	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MILEJKDO_01762	3.16e-313	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
MILEJKDO_01763	2.06e-278	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MILEJKDO_01764	1.3e-262	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MILEJKDO_01765	0.0	-	-	-	L	-	-	-	Transposase
MILEJKDO_01766	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
MILEJKDO_01768	1.43e-271	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MILEJKDO_01769	0.0	cadA	-	-	P	-	-	-	P-type ATPase
MILEJKDO_01770	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MILEJKDO_01771	1.75e-161	-	-	-	-	-	-	-	-
MILEJKDO_01772	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MILEJKDO_01773	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MILEJKDO_01775	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MILEJKDO_01776	9.58e-112	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
MILEJKDO_01777	9.77e-230	ydhF	-	-	S	-	-	-	Aldo keto reductase
MILEJKDO_01779	5.87e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MILEJKDO_01780	7.3e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MILEJKDO_01781	3.55e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MILEJKDO_01783	1.69e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MILEJKDO_01784	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MILEJKDO_01785	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
MILEJKDO_01786	3.83e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MILEJKDO_01787	9.51e-51	-	-	-	-	-	-	-	-
MILEJKDO_01788	3e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
MILEJKDO_01789	3.51e-308	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
MILEJKDO_01792	3.9e-265	isp	-	-	L	-	-	-	Transposase
MILEJKDO_01794	5.44e-28	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
MILEJKDO_01795	1.15e-37	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
MILEJKDO_01796	3.29e-61	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MILEJKDO_01798	1.26e-157	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MILEJKDO_01799	8.38e-28	-	-	-	-	-	-	-	-
MILEJKDO_01802	0.0	-	-	-	-	-	-	-	-
MILEJKDO_01803	3.45e-190	-	-	-	-	-	-	-	-
MILEJKDO_01804	1.95e-98	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MILEJKDO_01808	1.78e-48	-	-	-	D	-	-	-	nuclear chromosome segregation
MILEJKDO_01809	1.55e-09	-	-	-	K	-	-	-	Helix-turn-helix domain
MILEJKDO_01812	1.76e-36	-	-	-	-	-	-	-	-
MILEJKDO_01813	2.53e-71	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MILEJKDO_01818	1.06e-276	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MILEJKDO_01819	9.52e-124	-	-	-	S	-	-	-	AmiS/UreI family transporter
MILEJKDO_01820	4.88e-60	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
MILEJKDO_01821	2.83e-84	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
MILEJKDO_01822	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
MILEJKDO_01823	2.54e-101	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MILEJKDO_01824	1.97e-168	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MILEJKDO_01825	3.44e-146	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MILEJKDO_01826	9.18e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MILEJKDO_01827	2.34e-55	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MILEJKDO_01828	4.2e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MILEJKDO_01829	5.49e-237	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
MILEJKDO_01830	5.52e-182	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MILEJKDO_01831	9.42e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MILEJKDO_01832	7.17e-171	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
MILEJKDO_01833	2.14e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MILEJKDO_01834	1.86e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MILEJKDO_01835	7.4e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MILEJKDO_01836	4.47e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MILEJKDO_01837	2.89e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MILEJKDO_01838	1.03e-184	-	-	-	-	-	-	-	-
MILEJKDO_01840	2.48e-310	-	-	-	M	-	-	-	Glycosyl transferase
MILEJKDO_01841	2.33e-287	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MILEJKDO_01842	3.99e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MILEJKDO_01843	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MILEJKDO_01844	1.59e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MILEJKDO_01845	3.26e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
MILEJKDO_01846	1.08e-113	-	-	-	Q	-	-	-	Methyltransferase
MILEJKDO_01847	5.18e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MILEJKDO_01848	2.81e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MILEJKDO_01849	2.92e-204	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MILEJKDO_01850	6.31e-32	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MILEJKDO_01851	1.1e-218	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MILEJKDO_01852	1.6e-211	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MILEJKDO_01853	1.27e-140	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MILEJKDO_01854	7.04e-104	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MILEJKDO_01855	5.66e-29	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MILEJKDO_01856	2.1e-218	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MILEJKDO_01857	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MILEJKDO_01858	0.0	arcT	-	-	E	-	-	-	Dipeptidase
MILEJKDO_01859	8.01e-72	-	-	-	Q	-	-	-	Methyltransferase
MILEJKDO_01860	6.29e-193	nikA	-	-	E	ko:K15584	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Nickel ABC transporter
MILEJKDO_01861	2.84e-56	-	-	-	P	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
MILEJKDO_01862	1.51e-68	-	-	-	P	-	-	-	ABC transporter, permease protein
MILEJKDO_01863	2.02e-59	-	-	-	P	ko:K02031,ko:K02032,ko:K10823,ko:K13892,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MILEJKDO_01864	6.06e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
MILEJKDO_01865	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
MILEJKDO_01866	3.23e-177	-	-	-	V	-	-	-	Beta-lactamase enzyme family
MILEJKDO_01867	7.04e-288	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MILEJKDO_01868	6.26e-96	-	-	-	-	-	-	-	-
MILEJKDO_01869	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MILEJKDO_01870	4.47e-256	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MILEJKDO_01871	2.4e-37	-	-	-	-	-	-	-	-
MILEJKDO_01874	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
MILEJKDO_01875	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
MILEJKDO_01876	5.86e-211	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
MILEJKDO_01877	4.07e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MILEJKDO_01878	2.22e-206	mleR	-	-	K	-	-	-	LysR family
MILEJKDO_01879	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
MILEJKDO_01880	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MILEJKDO_01881	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MILEJKDO_01882	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MILEJKDO_01883	2.7e-200	-	-	-	K	-	-	-	LysR family
MILEJKDO_01884	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MILEJKDO_01885	1.91e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MILEJKDO_01886	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
MILEJKDO_01887	1.11e-240	-	-	-	I	-	-	-	Alpha beta
MILEJKDO_01888	7.25e-118	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MILEJKDO_01889	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MILEJKDO_01891	7.56e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MILEJKDO_01892	2.43e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MILEJKDO_01893	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MILEJKDO_01894	3.21e-99	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MILEJKDO_01895	1.92e-73	-	-	-	-	-	-	-	-
MILEJKDO_01896	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MILEJKDO_01897	2.39e-274	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MILEJKDO_01898	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MILEJKDO_01899	3.03e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MILEJKDO_01900	5.46e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MILEJKDO_01901	1.97e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MILEJKDO_01902	1.14e-106	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MILEJKDO_01903	2.34e-142	-	-	-	S	-	-	-	VIT family
MILEJKDO_01904	7.33e-152	-	-	-	S	-	-	-	membrane
MILEJKDO_01905	4.92e-213	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MILEJKDO_01906	1.15e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
MILEJKDO_01907	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MILEJKDO_01910	1.75e-243	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MILEJKDO_01911	2.86e-286	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MILEJKDO_01912	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MILEJKDO_01913	4.47e-199	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
MILEJKDO_01914	3.53e-269	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
MILEJKDO_01915	1.71e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MILEJKDO_01916	1.77e-205	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
MILEJKDO_01917	5.31e-139	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MILEJKDO_01918	6.62e-54	-	-	-	M	-	-	-	family 8
MILEJKDO_01920	1.26e-230	-	-	-	L	-	-	-	Transposase
MILEJKDO_01921	0.0	-	-	-	M	-	-	-	family 8
MILEJKDO_01922	6.92e-128	-	-	-	S	-	-	-	glycosyl transferase family 2
MILEJKDO_01923	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MILEJKDO_01924	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MILEJKDO_01925	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
MILEJKDO_01926	5.34e-190	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MILEJKDO_01927	1.45e-153	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MILEJKDO_01929	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MILEJKDO_01930	2.76e-212	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
MILEJKDO_01931	1.81e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MILEJKDO_01932	1.02e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MILEJKDO_01933	6.65e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MILEJKDO_01934	7.79e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
MILEJKDO_01935	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MILEJKDO_01936	4.96e-223	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MILEJKDO_01940	1.72e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MILEJKDO_01941	1.81e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MILEJKDO_01942	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MILEJKDO_01943	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MILEJKDO_01944	2.8e-231	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MILEJKDO_01945	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
MILEJKDO_01946	1.69e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MILEJKDO_01947	1.3e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MILEJKDO_01948	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MILEJKDO_01949	2.22e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
MILEJKDO_01950	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MILEJKDO_01951	4.08e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MILEJKDO_01952	4.88e-162	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MILEJKDO_01954	3.77e-123	-	-	-	-	-	-	-	-
MILEJKDO_01955	2.52e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MILEJKDO_01956	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MILEJKDO_01957	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MILEJKDO_01958	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MILEJKDO_01959	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MILEJKDO_01960	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MILEJKDO_01961	2.44e-20	-	-	-	-	-	-	-	-
MILEJKDO_01962	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
MILEJKDO_01963	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MILEJKDO_01964	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MILEJKDO_01965	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MILEJKDO_01966	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MILEJKDO_01967	2.32e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
MILEJKDO_01968	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MILEJKDO_01969	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MILEJKDO_01970	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MILEJKDO_01971	1.32e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MILEJKDO_01972	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MILEJKDO_01973	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MILEJKDO_01974	1.97e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MILEJKDO_01975	1.82e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MILEJKDO_01976	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MILEJKDO_01977	3.23e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MILEJKDO_01978	5.05e-57	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MILEJKDO_01979	1.85e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MILEJKDO_01980	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MILEJKDO_01981	4.1e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
MILEJKDO_01982	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MILEJKDO_01983	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
MILEJKDO_01984	1.06e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MILEJKDO_01985	1.9e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
MILEJKDO_01986	9.95e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MILEJKDO_01987	2.38e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MILEJKDO_01988	8.99e-104	-	-	-	-	-	-	-	-
MILEJKDO_01989	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MILEJKDO_01990	1.76e-231	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
MILEJKDO_01991	4.37e-39	-	-	-	-	-	-	-	-
MILEJKDO_01992	1.92e-229	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MILEJKDO_01994	3.71e-76	-	-	-	-	-	-	-	-
MILEJKDO_01995	2.83e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MILEJKDO_01996	5.21e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MILEJKDO_01997	3.27e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MILEJKDO_01998	1.89e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MILEJKDO_01999	4.62e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MILEJKDO_02000	9.46e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MILEJKDO_02001	3.78e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MILEJKDO_02002	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MILEJKDO_02003	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MILEJKDO_02004	5.95e-239	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MILEJKDO_02005	1.48e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MILEJKDO_02006	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MILEJKDO_02007	3.82e-157	-	-	-	S	-	-	-	repeat protein
MILEJKDO_02008	1.15e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
MILEJKDO_02009	8.77e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MILEJKDO_02010	2.27e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MILEJKDO_02011	1.1e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MILEJKDO_02012	9.75e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MILEJKDO_02013	1.54e-33	-	-	-	-	-	-	-	-
MILEJKDO_02014	1.01e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MILEJKDO_02015	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MILEJKDO_02016	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MILEJKDO_02017	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MILEJKDO_02018	5.05e-188	ylmH	-	-	S	-	-	-	S4 domain protein
MILEJKDO_02019	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MILEJKDO_02020	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MILEJKDO_02021	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MILEJKDO_02022	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MILEJKDO_02023	1.73e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MILEJKDO_02024	1.39e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MILEJKDO_02025	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MILEJKDO_02026	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MILEJKDO_02027	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MILEJKDO_02028	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MILEJKDO_02029	1.32e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MILEJKDO_02030	8.67e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MILEJKDO_02031	8.07e-76	-	-	-	-	-	-	-	-
MILEJKDO_02032	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MILEJKDO_02033	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MILEJKDO_02034	2.17e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MILEJKDO_02035	1.21e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
MILEJKDO_02036	3.25e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MILEJKDO_02038	1.69e-197	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MILEJKDO_02039	1.28e-18	-	-	-	-	-	-	-	-
MILEJKDO_02040	4.89e-282	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MILEJKDO_02041	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MILEJKDO_02042	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MILEJKDO_02043	4.12e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MILEJKDO_02044	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MILEJKDO_02045	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MILEJKDO_02046	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MILEJKDO_02047	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MILEJKDO_02048	1.13e-145	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
MILEJKDO_02049	6.32e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MILEJKDO_02050	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MILEJKDO_02051	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MILEJKDO_02052	0.0	-	-	-	S	-	-	-	membrane
MILEJKDO_02053	9.37e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MILEJKDO_02054	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MILEJKDO_02055	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MILEJKDO_02056	2.41e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
MILEJKDO_02057	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MILEJKDO_02058	4.27e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MILEJKDO_02059	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MILEJKDO_02060	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MILEJKDO_02061	2.71e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MILEJKDO_02062	2.45e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MILEJKDO_02063	1.11e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MILEJKDO_02064	3.32e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MILEJKDO_02065	1.74e-291	-	-	-	V	-	-	-	MatE
MILEJKDO_02066	0.0	potE	-	-	E	-	-	-	Amino Acid
MILEJKDO_02067	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MILEJKDO_02068	9.72e-156	csrR	-	-	K	-	-	-	response regulator
MILEJKDO_02069	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MILEJKDO_02070	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MILEJKDO_02071	6.82e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MILEJKDO_02072	2.91e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
MILEJKDO_02073	2.69e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MILEJKDO_02074	8.83e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MILEJKDO_02075	8.13e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MILEJKDO_02076	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
MILEJKDO_02077	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MILEJKDO_02078	7.78e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MILEJKDO_02079	2.93e-08	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MILEJKDO_02080	3.37e-57	-	-	-	K	-	-	-	Transcriptional regulator
MILEJKDO_02081	1.12e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
MILEJKDO_02082	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MILEJKDO_02083	2.76e-63	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MILEJKDO_02084	9.72e-138	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MILEJKDO_02085	6.42e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MILEJKDO_02086	6.98e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
MILEJKDO_02087	1.08e-173	gspA	-	-	M	-	-	-	family 8
MILEJKDO_02088	6.15e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MILEJKDO_02089	7.18e-126	-	-	-	-	-	-	-	-
MILEJKDO_02090	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
MILEJKDO_02091	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MILEJKDO_02092	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MILEJKDO_02093	2.62e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MILEJKDO_02094	4.8e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MILEJKDO_02095	2.34e-92	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MILEJKDO_02096	1.05e-84	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
MILEJKDO_02097	1.27e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
MILEJKDO_02098	1.03e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MILEJKDO_02099	2.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MILEJKDO_02100	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MILEJKDO_02101	4.41e-131	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MILEJKDO_02102	2.35e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MILEJKDO_02103	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MILEJKDO_02104	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
MILEJKDO_02105	9.68e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MILEJKDO_02106	6.66e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MILEJKDO_02107	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MILEJKDO_02108	2.56e-220	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
MILEJKDO_02109	5.59e-223	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MILEJKDO_02110	1.95e-272	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MILEJKDO_02111	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MILEJKDO_02112	3.22e-116	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MILEJKDO_02113	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MILEJKDO_02114	9.1e-237	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
MILEJKDO_02115	7.64e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MILEJKDO_02116	8.01e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MILEJKDO_02117	1.78e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
MILEJKDO_02118	5.25e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
MILEJKDO_02119	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
MILEJKDO_02120	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
MILEJKDO_02121	7.66e-192	-	-	-	O	-	-	-	Band 7 protein
MILEJKDO_02122	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MILEJKDO_02123	1.07e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MILEJKDO_02124	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
MILEJKDO_02125	3.26e-144	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
MILEJKDO_02126	1.11e-204	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MILEJKDO_02127	2.79e-75	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MILEJKDO_02128	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MILEJKDO_02129	4.52e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MILEJKDO_02130	3.17e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MILEJKDO_02131	1.66e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MILEJKDO_02132	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MILEJKDO_02133	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
MILEJKDO_02134	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MILEJKDO_02135	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MILEJKDO_02136	8.13e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MILEJKDO_02137	4.73e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
MILEJKDO_02138	6.8e-140	-	-	-	K	ko:K03091	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
MILEJKDO_02139	8.98e-274	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MILEJKDO_02140	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MILEJKDO_02141	1.74e-144	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
MILEJKDO_02142	2.72e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MILEJKDO_02143	9.19e-287	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MILEJKDO_02144	7.98e-123	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MILEJKDO_02145	4.62e-232	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MILEJKDO_02146	1.82e-228	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
MILEJKDO_02148	0.0	-	-	-	L	-	-	-	PLD-like domain
MILEJKDO_02149	6.93e-20	-	-	-	-	-	-	-	-
MILEJKDO_02151	5.23e-86	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
MILEJKDO_02152	1.68e-163	isp	-	-	L	-	-	-	Transposase
MILEJKDO_02153	7.85e-135	yocS	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
MILEJKDO_02154	1.6e-163	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MILEJKDO_02155	2.76e-103	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MILEJKDO_02156	1.02e-294	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MILEJKDO_02157	1.45e-260	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MILEJKDO_02158	7.73e-260	-	-	-	G	-	-	-	Major Facilitator Superfamily
MILEJKDO_02159	4.35e-198	menH	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MILEJKDO_02160	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MILEJKDO_02161	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
MILEJKDO_02162	1.77e-70	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MILEJKDO_02163	4.03e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF805)