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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
EPEMNGIC_00001	4.32e-08	comA	-	-	V	ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EPEMNGIC_00006	1.48e-26	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
EPEMNGIC_00007	2.52e-22	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
EPEMNGIC_00008	2.08e-30	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
EPEMNGIC_00009	1.19e-13	-	-	-	T	-	-	-	SpoVT / AbrB like domain
EPEMNGIC_00011	1.33e-76	-	-	-	-	-	-	-	-
EPEMNGIC_00015	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPEMNGIC_00017	5.23e-277	xylR	-	-	GK	-	-	-	ROK family
EPEMNGIC_00018	2.49e-39	-	-	-	-	-	-	-	-
EPEMNGIC_00019	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
EPEMNGIC_00020	5.54e-150	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
EPEMNGIC_00021	1.34e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
EPEMNGIC_00022	0.0	yclK	-	-	T	-	-	-	Histidine kinase
EPEMNGIC_00023	9.42e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
EPEMNGIC_00025	1.31e-108	lytE	-	-	M	-	-	-	Lysin motif
EPEMNGIC_00026	2.38e-85	-	-	-	L	-	-	-	Transposase
EPEMNGIC_00027	1.34e-187	-	-	-	L	-	-	-	Transposase
EPEMNGIC_00028	4.7e-282	-	-	-	L	-	-	-	transposase IS116 IS110 IS902 family protein
EPEMNGIC_00030	2.43e-64	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPEMNGIC_00031	1.77e-198	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
EPEMNGIC_00032	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPEMNGIC_00033	2.6e-215	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
EPEMNGIC_00034	8.25e-77	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EPEMNGIC_00035	1.21e-18	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EPEMNGIC_00036	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EPEMNGIC_00037	6.92e-128	-	-	-	S	-	-	-	glycosyl transferase family 2
EPEMNGIC_00038	0.0	-	-	-	M	-	-	-	family 8
EPEMNGIC_00039	3.78e-88	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EPEMNGIC_00040	1.05e-165	-	-	-	-	-	-	-	-
EPEMNGIC_00041	1.42e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
EPEMNGIC_00042	7.43e-45	-	-	-	-	-	-	-	-
EPEMNGIC_00043	8.15e-109	-	-	-	-	-	-	-	-
EPEMNGIC_00044	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EPEMNGIC_00045	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
EPEMNGIC_00046	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
EPEMNGIC_00047	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EPEMNGIC_00049	4.12e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
EPEMNGIC_00050	1.62e-263	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EPEMNGIC_00051	1.72e-94	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
EPEMNGIC_00052	1.23e-107	-	-	-	-	-	-	-	-
EPEMNGIC_00053	2.89e-36	-	-	-	M	-	-	-	biosynthesis protein
EPEMNGIC_00054	7.78e-96	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
EPEMNGIC_00055	7.27e-83	-	-	-	S	-	-	-	Glycosyltransferase like family
EPEMNGIC_00056	2.31e-96	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
EPEMNGIC_00057	4.11e-223	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EPEMNGIC_00058	1.46e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPEMNGIC_00059	1.29e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
EPEMNGIC_00060	2.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
EPEMNGIC_00061	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EPEMNGIC_00062	5.93e-265	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
EPEMNGIC_00063	9.02e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EPEMNGIC_00064	2.02e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EPEMNGIC_00065	3.75e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
EPEMNGIC_00066	2.64e-282	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
EPEMNGIC_00067	1.03e-148	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
EPEMNGIC_00068	2.22e-275	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
EPEMNGIC_00069	1.76e-128	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
EPEMNGIC_00070	1.33e-125	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EPEMNGIC_00071	1.56e-76	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EPEMNGIC_00072	3.81e-110	-	-	-	-	-	-	-	-
EPEMNGIC_00073	2.17e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
EPEMNGIC_00074	2.58e-71	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
EPEMNGIC_00075	6.8e-46	-	-	-	-	-	-	-	-
EPEMNGIC_00076	7.46e-121	isp	-	-	L	-	-	-	Transposase
EPEMNGIC_00077	5.23e-86	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
EPEMNGIC_00079	6.93e-20	-	-	-	-	-	-	-	-
EPEMNGIC_00080	0.0	-	-	-	L	-	-	-	PLD-like domain
EPEMNGIC_00082	1.82e-228	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
EPEMNGIC_00083	4.62e-232	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EPEMNGIC_00084	7.98e-123	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
EPEMNGIC_00085	9.19e-287	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
EPEMNGIC_00086	2.72e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
EPEMNGIC_00087	1.74e-144	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
EPEMNGIC_00088	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
EPEMNGIC_00089	8.98e-274	-	-	-	G	-	-	-	Transporter, major facilitator family protein
EPEMNGIC_00090	6.8e-140	-	-	-	K	ko:K03091	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
EPEMNGIC_00091	4.73e-85	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
EPEMNGIC_00092	8.13e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EPEMNGIC_00093	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
EPEMNGIC_00094	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
EPEMNGIC_00095	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
EPEMNGIC_00096	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
EPEMNGIC_00097	1.66e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
EPEMNGIC_00098	3.17e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPEMNGIC_00099	4.52e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
EPEMNGIC_00100	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
EPEMNGIC_00101	2.79e-75	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
EPEMNGIC_00102	1.11e-204	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
EPEMNGIC_00103	3.26e-144	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
EPEMNGIC_00104	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
EPEMNGIC_00105	1.07e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
EPEMNGIC_00106	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
EPEMNGIC_00107	7.66e-192	-	-	-	O	-	-	-	Band 7 protein
EPEMNGIC_00108	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
EPEMNGIC_00109	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
EPEMNGIC_00110	1.41e-54	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
EPEMNGIC_00111	1.78e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
EPEMNGIC_00112	8.01e-228	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EPEMNGIC_00113	7.64e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
EPEMNGIC_00114	9.1e-237	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
EPEMNGIC_00115	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
EPEMNGIC_00116	3.22e-116	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
EPEMNGIC_00117	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EPEMNGIC_00118	1.95e-272	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
EPEMNGIC_00119	5.59e-223	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
EPEMNGIC_00120	2.56e-220	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
EPEMNGIC_00121	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
EPEMNGIC_00122	6.66e-115	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
EPEMNGIC_00123	9.68e-159	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
EPEMNGIC_00124	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
EPEMNGIC_00125	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
EPEMNGIC_00126	2.35e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EPEMNGIC_00127	4.41e-131	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
EPEMNGIC_00128	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EPEMNGIC_00129	2.05e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
EPEMNGIC_00130	1.03e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
EPEMNGIC_00131	1.27e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
EPEMNGIC_00132	1.05e-84	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
EPEMNGIC_00133	2.34e-92	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPEMNGIC_00134	4.8e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EPEMNGIC_00135	2.62e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
EPEMNGIC_00136	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
EPEMNGIC_00137	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
EPEMNGIC_00138	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
EPEMNGIC_00139	7.18e-126	-	-	-	-	-	-	-	-
EPEMNGIC_00140	6.15e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EPEMNGIC_00141	1.08e-173	gspA	-	-	M	-	-	-	family 8
EPEMNGIC_00142	8.69e-161	-	-	-	S	-	-	-	Alpha beta hydrolase
EPEMNGIC_00143	3.69e-31	-	-	-	S	-	-	-	Alpha beta hydrolase
EPEMNGIC_00144	6.42e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EPEMNGIC_00145	9.72e-138	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
EPEMNGIC_00146	2.76e-63	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
EPEMNGIC_00147	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
EPEMNGIC_00148	1.12e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
EPEMNGIC_00149	3.37e-57	-	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_00150	1.05e-194	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPEMNGIC_00151	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
EPEMNGIC_00152	5.31e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
EPEMNGIC_00153	2.18e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
EPEMNGIC_00154	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EPEMNGIC_00155	6.07e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPEMNGIC_00156	3.13e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
EPEMNGIC_00157	2.02e-62	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
EPEMNGIC_00158	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
EPEMNGIC_00159	3.8e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
EPEMNGIC_00160	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
EPEMNGIC_00161	8.98e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPEMNGIC_00162	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
EPEMNGIC_00163	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
EPEMNGIC_00164	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPEMNGIC_00165	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPEMNGIC_00166	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPEMNGIC_00167	7.99e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPEMNGIC_00168	6.21e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPEMNGIC_00169	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPEMNGIC_00170	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
EPEMNGIC_00171	8.02e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
EPEMNGIC_00172	3.32e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
EPEMNGIC_00173	9.53e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
EPEMNGIC_00174	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPEMNGIC_00175	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPEMNGIC_00176	2.58e-293	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPEMNGIC_00177	5.39e-251	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EPEMNGIC_00178	3.9e-210	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPEMNGIC_00179	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPEMNGIC_00180	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
EPEMNGIC_00181	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
EPEMNGIC_00182	1.63e-171	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
EPEMNGIC_00183	4.84e-298	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
EPEMNGIC_00184	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
EPEMNGIC_00185	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EPEMNGIC_00186	8.44e-303	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
EPEMNGIC_00187	4.91e-241	ampC	-	-	V	-	-	-	Beta-lactamase
EPEMNGIC_00188	3.83e-74	-	-	-	-	-	-	-	-
EPEMNGIC_00189	0.0	-	-	-	M	-	-	-	domain protein
EPEMNGIC_00190	2.27e-138	-	-	-	-	-	-	-	-
EPEMNGIC_00192	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EPEMNGIC_00193	1.28e-75	-	-	-	-	-	-	-	-
EPEMNGIC_00195	2.69e-114	-	-	-	-	-	-	-	-
EPEMNGIC_00196	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
EPEMNGIC_00197	8.97e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
EPEMNGIC_00198	1.6e-82	-	-	-	S	-	-	-	Cupredoxin-like domain
EPEMNGIC_00199	4.07e-133	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
EPEMNGIC_00200	1.38e-200	-	-	-	EG	-	-	-	EamA-like transporter family
EPEMNGIC_00201	2.28e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
EPEMNGIC_00202	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPEMNGIC_00203	4.34e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
EPEMNGIC_00204	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
EPEMNGIC_00205	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
EPEMNGIC_00206	8.8e-17	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
EPEMNGIC_00207	1.15e-37	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
EPEMNGIC_00208	3.29e-61	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
EPEMNGIC_00210	1.26e-157	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_00211	8.38e-28	-	-	-	-	-	-	-	-
EPEMNGIC_00214	0.0	-	-	-	-	-	-	-	-
EPEMNGIC_00215	3.45e-190	-	-	-	-	-	-	-	-
EPEMNGIC_00216	3.6e-67	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
EPEMNGIC_00217	3.33e-126	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPEMNGIC_00218	6.46e-66	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EPEMNGIC_00219	1.24e-42	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPEMNGIC_00220	5.03e-190	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
EPEMNGIC_00221	9.08e-153	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
EPEMNGIC_00222	7.84e-71	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
EPEMNGIC_00223	3.61e-60	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
EPEMNGIC_00224	1.94e-134	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
EPEMNGIC_00225	2.7e-70	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EPEMNGIC_00226	2.11e-174	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
EPEMNGIC_00227	6.26e-96	-	-	-	-	-	-	-	-
EPEMNGIC_00228	7.04e-288	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EPEMNGIC_00229	3.23e-177	-	-	-	V	-	-	-	Beta-lactamase enzyme family
EPEMNGIC_00230	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
EPEMNGIC_00231	6.06e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
EPEMNGIC_00232	1.09e-66	-	-	-	S	-	-	-	AAA ATPase domain
EPEMNGIC_00233	0.000616	-	-	-	S	-	-	-	SPFH domain-Band 7 family
EPEMNGIC_00234	1.09e-26	-	-	-	-	-	-	-	-
EPEMNGIC_00236	3.08e-34	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPEMNGIC_00237	4.03e-25	-	-	-	-	-	-	-	-
EPEMNGIC_00241	8.04e-27	-	-	-	-	-	-	-	-
EPEMNGIC_00244	1.79e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
EPEMNGIC_00245	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EPEMNGIC_00246	2.57e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_00247	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
EPEMNGIC_00249	4.46e-78	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
EPEMNGIC_00250	4.29e-29	-	-	-	-	-	-	-	-
EPEMNGIC_00251	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
EPEMNGIC_00252	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
EPEMNGIC_00253	6.02e-219	-	-	-	S	-	-	-	Phage Mu protein F like protein
EPEMNGIC_00255	6.46e-95	-	-	-	-	-	-	-	-
EPEMNGIC_00256	1.97e-153	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
EPEMNGIC_00257	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPEMNGIC_00258	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPEMNGIC_00259	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPEMNGIC_00260	1.5e-78	isp	-	-	L	-	-	-	Transposase
EPEMNGIC_00261	1.81e-222	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
EPEMNGIC_00262	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
EPEMNGIC_00263	0.0	-	-	-	G	-	-	-	Right handed beta helix region
EPEMNGIC_00264	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
EPEMNGIC_00265	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPEMNGIC_00266	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPEMNGIC_00267	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
EPEMNGIC_00269	1.45e-225	-	-	-	M	-	-	-	Glycosyl transferase family group 2
EPEMNGIC_00270	4.04e-264	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EPEMNGIC_00271	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPEMNGIC_00272	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPEMNGIC_00273	1.68e-64	-	-	-	-	-	-	-	-
EPEMNGIC_00275	2.94e-65	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPEMNGIC_00276	9.71e-76	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
EPEMNGIC_00277	8.01e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
EPEMNGIC_00278	1.49e-175	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
EPEMNGIC_00279	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
EPEMNGIC_00280	3.81e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPEMNGIC_00281	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPEMNGIC_00282	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
EPEMNGIC_00283	7.25e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPEMNGIC_00284	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPEMNGIC_00285	6.86e-61	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EPEMNGIC_00286	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPEMNGIC_00287	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
EPEMNGIC_00288	6.4e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPEMNGIC_00289	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
EPEMNGIC_00290	3.7e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EPEMNGIC_00291	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
EPEMNGIC_00292	3.17e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPEMNGIC_00293	1.28e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
EPEMNGIC_00294	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EPEMNGIC_00295	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EPEMNGIC_00296	6.8e-224	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EPEMNGIC_00297	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
EPEMNGIC_00298	1.22e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
EPEMNGIC_00299	4.12e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
EPEMNGIC_00300	5.83e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPEMNGIC_00301	1.26e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPEMNGIC_00302	8.21e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPEMNGIC_00303	2.2e-178	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPEMNGIC_00304	9e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
EPEMNGIC_00305	4.39e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EPEMNGIC_00306	6.9e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPEMNGIC_00307	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
EPEMNGIC_00308	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EPEMNGIC_00309	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPEMNGIC_00310	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPEMNGIC_00311	6.02e-104	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
EPEMNGIC_00312	0.0	-	-	-	E	-	-	-	amino acid
EPEMNGIC_00313	0.0	ydaO	-	-	E	-	-	-	amino acid
EPEMNGIC_00314	1.78e-51	-	-	-	-	-	-	-	-
EPEMNGIC_00315	4.03e-85	-	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_00316	5.74e-31	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_00317	1.33e-110	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_00318	3.26e-95	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_00319	1.91e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
EPEMNGIC_00320	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
EPEMNGIC_00321	4.87e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
EPEMNGIC_00322	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPEMNGIC_00323	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPEMNGIC_00324	1.11e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPEMNGIC_00325	2.47e-65	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
EPEMNGIC_00326	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
EPEMNGIC_00327	2.29e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EPEMNGIC_00328	3.18e-198	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPEMNGIC_00329	2.31e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
EPEMNGIC_00330	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
EPEMNGIC_00331	3.55e-175	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
EPEMNGIC_00332	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
EPEMNGIC_00333	1.2e-200	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
EPEMNGIC_00334	3.37e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPEMNGIC_00335	7.51e-265	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
EPEMNGIC_00336	2.96e-208	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
EPEMNGIC_00337	6.99e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
EPEMNGIC_00338	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
EPEMNGIC_00347	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPEMNGIC_00348	1.36e-80	-	-	-	M	-	-	-	Glycosyl transferase family 2
EPEMNGIC_00349	1.38e-195	-	-	-	J	-	-	-	Methyltransferase
EPEMNGIC_00350	1.3e-71	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
EPEMNGIC_00351	1.02e-61	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPEMNGIC_00352	1.29e-204	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPEMNGIC_00353	3.62e-131	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
EPEMNGIC_00354	1.54e-100	-	-	-	-	-	-	-	-
EPEMNGIC_00355	1.62e-229	-	-	-	-	-	-	-	-
EPEMNGIC_00356	1.45e-233	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
EPEMNGIC_00357	4.82e-180	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
EPEMNGIC_00358	6.11e-104	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EPEMNGIC_00359	1.87e-74	-	-	-	S	-	-	-	Pfam:DUF59
EPEMNGIC_00360	2.37e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EPEMNGIC_00361	1.17e-21	-	-	-	K	-	-	-	Transcriptional regulator, LacI family
EPEMNGIC_00362	4.1e-111	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
EPEMNGIC_00363	5.86e-118	-	-	-	L	-	-	-	Integrase
EPEMNGIC_00364	4.8e-19	XK27_09155	-	-	K	-	-	-	Transcriptional
EPEMNGIC_00365	1.34e-199	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
EPEMNGIC_00366	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPEMNGIC_00367	1.68e-55	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
EPEMNGIC_00368	7.72e-184	wchF	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
EPEMNGIC_00369	2.03e-156	-	-	-	G	-	-	-	Glycosyltransferase Family 4
EPEMNGIC_00370	4.6e-91	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
EPEMNGIC_00371	2.37e-36	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EPEMNGIC_00372	2.07e-218	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
EPEMNGIC_00373	2.6e-182	epsB	-	-	M	-	-	-	biosynthesis protein
EPEMNGIC_00374	9.25e-152	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
EPEMNGIC_00375	1.17e-137	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
EPEMNGIC_00376	4.3e-18	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
EPEMNGIC_00377	3.64e-175	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_00379	4.77e-65	yrvD	-	-	S	-	-	-	Pfam:DUF1049
EPEMNGIC_00380	1.54e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
EPEMNGIC_00381	7.49e-283	-	-	-	V	-	-	-	N-6 DNA Methylase
EPEMNGIC_00383	1.52e-177	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
EPEMNGIC_00387	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
EPEMNGIC_00388	2.34e-92	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
EPEMNGIC_00389	2.15e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EPEMNGIC_00390	3.59e-304	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPEMNGIC_00391	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
EPEMNGIC_00392	2.99e-95	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
EPEMNGIC_00393	8.14e-216	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EPEMNGIC_00394	8.7e-233	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
EPEMNGIC_00395	7.1e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPEMNGIC_00396	7.06e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
EPEMNGIC_00397	8.55e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPEMNGIC_00398	1.45e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
EPEMNGIC_00399	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
EPEMNGIC_00400	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
EPEMNGIC_00401	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPEMNGIC_00402	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPEMNGIC_00403	5.91e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EPEMNGIC_00404	1.68e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
EPEMNGIC_00405	6.19e-200	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EPEMNGIC_00406	4.04e-304	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
EPEMNGIC_00407	1.11e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
EPEMNGIC_00408	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
EPEMNGIC_00409	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
EPEMNGIC_00410	3.23e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
EPEMNGIC_00411	2.45e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
EPEMNGIC_00412	2.49e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EPEMNGIC_00413	1.67e-178	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EPEMNGIC_00414	3.18e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EPEMNGIC_00415	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
EPEMNGIC_00416	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPEMNGIC_00417	2.84e-241	-	-	-	S	-	-	-	Helix-turn-helix domain
EPEMNGIC_00418	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
EPEMNGIC_00419	1.31e-65	-	-	-	M	-	-	-	Lysin motif
EPEMNGIC_00420	7.04e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
EPEMNGIC_00421	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
EPEMNGIC_00422	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
EPEMNGIC_00423	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EPEMNGIC_00424	5.26e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
EPEMNGIC_00425	3.33e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EPEMNGIC_00426	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_00427	5.75e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPEMNGIC_00428	3.79e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EPEMNGIC_00429	4.3e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
EPEMNGIC_00430	9.07e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
EPEMNGIC_00431	2.66e-218	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
EPEMNGIC_00432	5.52e-139	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
EPEMNGIC_00433	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
EPEMNGIC_00434	7.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EPEMNGIC_00435	1.01e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPEMNGIC_00436	6.17e-204	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
EPEMNGIC_00437	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPEMNGIC_00438	6.76e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
EPEMNGIC_00439	1.56e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EPEMNGIC_00440	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPEMNGIC_00441	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EPEMNGIC_00442	4.2e-110	-	-	-	F	-	-	-	Hydrolase, NUDIX family
EPEMNGIC_00443	8.96e-223	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
EPEMNGIC_00444	3.67e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
EPEMNGIC_00445	5.5e-67	-	-	-	-	-	-	-	-
EPEMNGIC_00447	2.28e-118	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
EPEMNGIC_00448	4.49e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
EPEMNGIC_00449	3.09e-35	-	-	-	-	-	-	-	-
EPEMNGIC_00450	3.97e-125	-	-	-	-	-	-	-	-
EPEMNGIC_00451	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
EPEMNGIC_00452	8.65e-230	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
EPEMNGIC_00453	2.44e-280	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
EPEMNGIC_00454	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
EPEMNGIC_00455	3.42e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EPEMNGIC_00456	1.38e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
EPEMNGIC_00457	1.75e-29	-	-	-	-	-	-	-	-
EPEMNGIC_00458	3.09e-211	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EPEMNGIC_00459	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
EPEMNGIC_00460	6.49e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
EPEMNGIC_00461	1.29e-93	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_00463	1.14e-07	-	-	-	K	-	-	-	Peptidase S24-like
EPEMNGIC_00465	6.21e-309	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EPEMNGIC_00466	4.47e-256	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
EPEMNGIC_00471	9.26e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EPEMNGIC_00472	5.58e-126	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPEMNGIC_00473	3.87e-111	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
EPEMNGIC_00474	1.56e-254	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_00476	4.64e-271	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
EPEMNGIC_00477	6.77e-61	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPEMNGIC_00478	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EPEMNGIC_00479	7.12e-171	-	-	-	O	-	-	-	Bacterial dnaA protein
EPEMNGIC_00480	2.72e-303	-	-	-	L	-	-	-	Integrase core domain
EPEMNGIC_00481	1.19e-49	lpg2	2.4.1.337	GT4	M	ko:K00754,ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	transferase activity, transferring glycosyl groups
EPEMNGIC_00482	2.15e-89	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
EPEMNGIC_00483	5.99e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPEMNGIC_00484	1.94e-227	-	-	-	-	-	-	-	-
EPEMNGIC_00485	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPEMNGIC_00486	2.76e-308	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
EPEMNGIC_00487	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
EPEMNGIC_00488	4.78e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EPEMNGIC_00489	7.51e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
EPEMNGIC_00490	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPEMNGIC_00491	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPEMNGIC_00492	1.9e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPEMNGIC_00493	6.16e-48	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EPEMNGIC_00494	1.75e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
EPEMNGIC_00495	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EPEMNGIC_00496	9.04e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPEMNGIC_00497	7.36e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPEMNGIC_00498	4.28e-128	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPEMNGIC_00499	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
EPEMNGIC_00500	1.26e-232	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
EPEMNGIC_00501	4.79e-161	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
EPEMNGIC_00502	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
EPEMNGIC_00503	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
EPEMNGIC_00504	1.94e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
EPEMNGIC_00505	9.49e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
EPEMNGIC_00506	2.61e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
EPEMNGIC_00507	5.26e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPEMNGIC_00508	7.97e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EPEMNGIC_00509	1.6e-219	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPEMNGIC_00510	6.82e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPEMNGIC_00511	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
EPEMNGIC_00512	3.12e-105	-	-	-	K	-	-	-	LysR substrate binding domain
EPEMNGIC_00513	1.53e-39	-	-	-	K	-	-	-	LysR substrate binding domain
EPEMNGIC_00514	9.94e-71	-	-	-	S	-	-	-	branched-chain amino acid
EPEMNGIC_00515	3.97e-185	-	-	-	E	-	-	-	AzlC protein
EPEMNGIC_00516	6.19e-263	hpk31	-	-	T	-	-	-	Histidine kinase
EPEMNGIC_00517	9.76e-161	vanR	-	-	K	-	-	-	response regulator
EPEMNGIC_00518	2.84e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPEMNGIC_00519	2.18e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
EPEMNGIC_00520	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
EPEMNGIC_00521	8.18e-303	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
EPEMNGIC_00522	1.97e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPEMNGIC_00523	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EPEMNGIC_00524	1.81e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
EPEMNGIC_00525	5.01e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPEMNGIC_00526	5.8e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
EPEMNGIC_00527	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EPEMNGIC_00528	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
EPEMNGIC_00529	6.46e-201	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
EPEMNGIC_00530	9.71e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
EPEMNGIC_00531	4.03e-206	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
EPEMNGIC_00532	2.37e-218	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
EPEMNGIC_00533	3.42e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
EPEMNGIC_00534	1.24e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EPEMNGIC_00535	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_00536	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPEMNGIC_00537	1.21e-50	-	-	-	L	-	-	-	four-way junction helicase activity
EPEMNGIC_00539	1.96e-109	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	Peptidase C39 family
EPEMNGIC_00540	5.11e-120	-	-	-	-	-	-	-	-
EPEMNGIC_00544	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
EPEMNGIC_00545	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
EPEMNGIC_00546	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
EPEMNGIC_00549	4e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EPEMNGIC_00550	2.98e-252	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_00551	4.38e-175	-	-	-	M	-	-	-	Lysin motif
EPEMNGIC_00552	1.63e-104	-	-	-	-	-	-	-	-
EPEMNGIC_00553	1.54e-217	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
EPEMNGIC_00554	7.23e-124	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
EPEMNGIC_00555	3.69e-203	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
EPEMNGIC_00556	3.7e-19	-	-	-	-	-	-	-	-
EPEMNGIC_00557	4.44e-117	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
EPEMNGIC_00558	6.29e-250	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
EPEMNGIC_00559	1.71e-144	-	-	-	S	-	-	-	Membrane
EPEMNGIC_00560	1.1e-161	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
EPEMNGIC_00561	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPEMNGIC_00562	1.3e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EPEMNGIC_00564	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EPEMNGIC_00565	9.57e-106	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EPEMNGIC_00566	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EPEMNGIC_00567	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EPEMNGIC_00568	3.47e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
EPEMNGIC_00569	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPEMNGIC_00570	4.8e-221	-	-	-	-	-	-	-	-
EPEMNGIC_00572	4.98e-32	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPEMNGIC_00573	2.68e-30	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPEMNGIC_00574	2.23e-124	-	-	-	K	-	-	-	acetyltransferase
EPEMNGIC_00575	6.33e-28	-	-	-	-	-	-	-	-
EPEMNGIC_00576	5.55e-41	-	-	-	-	-	-	-	-
EPEMNGIC_00577	6.97e-40	-	-	-	-	-	-	-	-
EPEMNGIC_00585	1.26e-60	-	-	-	-	-	-	-	-
EPEMNGIC_00586	1.16e-29	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
EPEMNGIC_00587	1.87e-19	-	-	-	S	-	-	-	Acyltransferase family
EPEMNGIC_00594	7.06e-64	-	-	-	E	-	-	-	Filamentation induced by cAMP protein fic
EPEMNGIC_00595	1.54e-97	-	-	-	S	-	-	-	Fic/DOC family
EPEMNGIC_00596	9.48e-130	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EPEMNGIC_00597	4.41e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
EPEMNGIC_00598	4e-202	-	-	-	-	-	-	-	-
EPEMNGIC_00599	2.09e-223	-	-	-	-	-	-	-	-
EPEMNGIC_00600	1.36e-112	-	-	-	S	-	-	-	Protein conserved in bacteria
EPEMNGIC_00603	5.7e-146	-	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_00604	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
EPEMNGIC_00605	5.08e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
EPEMNGIC_00606	7.2e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
EPEMNGIC_00607	4.82e-164	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPEMNGIC_00608	1.18e-253	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
EPEMNGIC_00609	4.37e-141	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
EPEMNGIC_00610	1.32e-92	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
EPEMNGIC_00611	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPEMNGIC_00612	6.56e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPEMNGIC_00613	1.09e-309	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPEMNGIC_00614	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPEMNGIC_00615	3.54e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EPEMNGIC_00616	1.97e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
EPEMNGIC_00617	2.25e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
EPEMNGIC_00618	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
EPEMNGIC_00619	7.4e-71	-	-	-	-	-	-	-	-
EPEMNGIC_00620	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
EPEMNGIC_00621	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPEMNGIC_00622	1.17e-268	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPEMNGIC_00623	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPEMNGIC_00624	4.98e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPEMNGIC_00625	1.63e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EPEMNGIC_00626	3.5e-167	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
EPEMNGIC_00627	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
EPEMNGIC_00628	1.03e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EPEMNGIC_00629	1.5e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
EPEMNGIC_00630	8.12e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
EPEMNGIC_00631	3.15e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
EPEMNGIC_00632	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
EPEMNGIC_00633	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
EPEMNGIC_00634	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EPEMNGIC_00635	8.38e-235	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EPEMNGIC_00636	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EPEMNGIC_00637	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPEMNGIC_00638	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
EPEMNGIC_00639	2e-283	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPEMNGIC_00640	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EPEMNGIC_00641	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPEMNGIC_00642	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
EPEMNGIC_00643	4.38e-52	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
EPEMNGIC_00644	2.96e-116	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPEMNGIC_00645	7.76e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
EPEMNGIC_00646	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
EPEMNGIC_00647	3.75e-77	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPEMNGIC_00651	5.29e-86	-	-	-	M	-	-	-	Glycosyl transferase family 2
EPEMNGIC_00655	3.71e-76	-	-	-	-	-	-	-	-
EPEMNGIC_00656	2.83e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
EPEMNGIC_00657	5.21e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPEMNGIC_00658	3.27e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EPEMNGIC_00659	1.89e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPEMNGIC_00660	4.62e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPEMNGIC_00661	9.46e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EPEMNGIC_00662	3.78e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EPEMNGIC_00663	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPEMNGIC_00664	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
EPEMNGIC_00665	1.71e-238	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EPEMNGIC_00666	1.48e-223	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPEMNGIC_00667	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EPEMNGIC_00668	3.82e-157	-	-	-	S	-	-	-	repeat protein
EPEMNGIC_00669	1.15e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
EPEMNGIC_00670	8.77e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EPEMNGIC_00671	2.27e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
EPEMNGIC_00672	1.1e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
EPEMNGIC_00673	9.75e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPEMNGIC_00674	1.54e-33	-	-	-	-	-	-	-	-
EPEMNGIC_00675	1.01e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
EPEMNGIC_00676	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
EPEMNGIC_00677	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPEMNGIC_00678	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
EPEMNGIC_00679	5.05e-188	ylmH	-	-	S	-	-	-	S4 domain protein
EPEMNGIC_00680	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
EPEMNGIC_00681	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPEMNGIC_00682	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPEMNGIC_00683	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EPEMNGIC_00684	1.73e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EPEMNGIC_00685	1.39e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPEMNGIC_00686	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPEMNGIC_00687	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPEMNGIC_00688	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EPEMNGIC_00689	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
EPEMNGIC_00690	1.32e-223	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPEMNGIC_00691	8.67e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
EPEMNGIC_00692	8.07e-76	-	-	-	-	-	-	-	-
EPEMNGIC_00693	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
EPEMNGIC_00694	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
EPEMNGIC_00695	2.17e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPEMNGIC_00696	1.21e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
EPEMNGIC_00697	3.25e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
EPEMNGIC_00703	9.82e-92	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EPEMNGIC_00704	5.53e-243	-	-	-	L	-	-	-	PFAM Integrase catalytic region
EPEMNGIC_00705	1.27e-29	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EPEMNGIC_00706	3.03e-188	-	-	-	S	-	-	-	Cof-like hydrolase
EPEMNGIC_00707	1.23e-103	-	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_00708	0.0	oatA	-	-	I	-	-	-	Acyltransferase
EPEMNGIC_00709	1.04e-69	-	-	-	-	-	-	-	-
EPEMNGIC_00710	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPEMNGIC_00711	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPEMNGIC_00712	3.51e-161	ybbR	-	-	S	-	-	-	YbbR-like protein
EPEMNGIC_00713	4.46e-193	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EPEMNGIC_00714	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
EPEMNGIC_00715	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
EPEMNGIC_00716	1.86e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPEMNGIC_00717	3.36e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
EPEMNGIC_00718	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
EPEMNGIC_00719	2.92e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
EPEMNGIC_00720	6.2e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
EPEMNGIC_00721	1.71e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
EPEMNGIC_00722	1.97e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
EPEMNGIC_00723	7.51e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPEMNGIC_00724	3.91e-136	-	-	-	-	-	-	-	-
EPEMNGIC_00725	3.15e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EPEMNGIC_00726	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EPEMNGIC_00727	1.4e-188	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
EPEMNGIC_00728	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
EPEMNGIC_00729	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EPEMNGIC_00730	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
EPEMNGIC_00731	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPEMNGIC_00732	7.18e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPEMNGIC_00733	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
EPEMNGIC_00734	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPEMNGIC_00736	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPEMNGIC_00737	2.04e-308	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
EPEMNGIC_00738	1.83e-21	-	-	-	-	-	-	-	-
EPEMNGIC_00740	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
EPEMNGIC_00741	1.41e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
EPEMNGIC_00742	3.83e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
EPEMNGIC_00743	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
EPEMNGIC_00744	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPEMNGIC_00745	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPEMNGIC_00746	1.03e-19	-	-	-	-	-	-	-	-
EPEMNGIC_00747	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
EPEMNGIC_00748	6.56e-223	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
EPEMNGIC_00749	1.05e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
EPEMNGIC_00750	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EPEMNGIC_00751	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
EPEMNGIC_00752	8.07e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
EPEMNGIC_00753	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
EPEMNGIC_00754	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPEMNGIC_00755	1.37e-290	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EPEMNGIC_00756	3.62e-269	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
EPEMNGIC_00757	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EPEMNGIC_00758	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPEMNGIC_00759	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
EPEMNGIC_00760	7.61e-217	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
EPEMNGIC_00761	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
EPEMNGIC_00762	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
EPEMNGIC_00763	1.6e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
EPEMNGIC_00764	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
EPEMNGIC_00765	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
EPEMNGIC_00766	3.02e-174	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
EPEMNGIC_00767	2.41e-179	-	-	-	S	-	-	-	Membrane
EPEMNGIC_00768	1.16e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
EPEMNGIC_00769	1.97e-28	-	-	-	-	-	-	-	-
EPEMNGIC_00770	2.47e-112	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
EPEMNGIC_00771	6.57e-310	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
EPEMNGIC_00772	3.61e-61	-	-	-	-	-	-	-	-
EPEMNGIC_00773	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
EPEMNGIC_00774	1.2e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
EPEMNGIC_00775	1.15e-198	yvgN	-	-	S	-	-	-	Aldo keto reductase
EPEMNGIC_00776	3.88e-120	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
EPEMNGIC_00777	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
EPEMNGIC_00778	4.5e-177	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
EPEMNGIC_00779	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
EPEMNGIC_00780	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
EPEMNGIC_00783	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
EPEMNGIC_00784	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
EPEMNGIC_00785	5.86e-211	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
EPEMNGIC_00786	4.07e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPEMNGIC_00787	2.22e-206	mleR	-	-	K	-	-	-	LysR family
EPEMNGIC_00788	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
EPEMNGIC_00789	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
EPEMNGIC_00790	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
EPEMNGIC_00791	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
EPEMNGIC_00792	2.7e-200	-	-	-	K	-	-	-	LysR family
EPEMNGIC_00793	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
EPEMNGIC_00794	1.91e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
EPEMNGIC_00795	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_00796	1.11e-240	-	-	-	I	-	-	-	Alpha beta
EPEMNGIC_00797	7.25e-118	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
EPEMNGIC_00798	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPEMNGIC_00800	7.56e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
EPEMNGIC_00801	2.43e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
EPEMNGIC_00802	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EPEMNGIC_00803	3.21e-99	-	-	-	K	-	-	-	MerR HTH family regulatory protein
EPEMNGIC_00804	1.92e-73	-	-	-	-	-	-	-	-
EPEMNGIC_00805	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPEMNGIC_00806	2.39e-274	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EPEMNGIC_00807	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EPEMNGIC_00808	3.03e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EPEMNGIC_00809	5.46e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPEMNGIC_00810	1.97e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_00811	1.14e-106	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
EPEMNGIC_00812	2.34e-142	-	-	-	S	-	-	-	VIT family
EPEMNGIC_00813	7.33e-152	-	-	-	S	-	-	-	membrane
EPEMNGIC_00814	4.92e-213	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
EPEMNGIC_00815	1.15e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
EPEMNGIC_00816	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
EPEMNGIC_00818	1.69e-197	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EPEMNGIC_00819	1.28e-18	-	-	-	-	-	-	-	-
EPEMNGIC_00820	4.89e-282	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EPEMNGIC_00821	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPEMNGIC_00822	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
EPEMNGIC_00823	4.12e-226	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPEMNGIC_00824	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
EPEMNGIC_00825	7.66e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
EPEMNGIC_00826	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
EPEMNGIC_00827	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
EPEMNGIC_00828	1.13e-145	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
EPEMNGIC_00829	6.32e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EPEMNGIC_00830	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EPEMNGIC_00831	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
EPEMNGIC_00832	0.0	-	-	-	S	-	-	-	membrane
EPEMNGIC_00833	9.37e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
EPEMNGIC_00834	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPEMNGIC_00835	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
EPEMNGIC_00836	2.41e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
EPEMNGIC_00837	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPEMNGIC_00838	4.27e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPEMNGIC_00839	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EPEMNGIC_00840	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
EPEMNGIC_00841	2.71e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPEMNGIC_00842	2.45e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
EPEMNGIC_00843	1.11e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPEMNGIC_00844	3.32e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
EPEMNGIC_00845	1.74e-291	-	-	-	V	-	-	-	MatE
EPEMNGIC_00846	0.0	potE	-	-	E	-	-	-	Amino Acid
EPEMNGIC_00847	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPEMNGIC_00848	9.72e-156	csrR	-	-	K	-	-	-	response regulator
EPEMNGIC_00849	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
EPEMNGIC_00850	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
EPEMNGIC_00851	6.82e-274	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
EPEMNGIC_00852	2.91e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
EPEMNGIC_00853	2.69e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPEMNGIC_00854	8.83e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
EPEMNGIC_00855	8.13e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPEMNGIC_00856	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
EPEMNGIC_00857	5.44e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
EPEMNGIC_00858	7.78e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
EPEMNGIC_00859	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPEMNGIC_00860	2.18e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
EPEMNGIC_00861	6.35e-176	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPEMNGIC_00862	3.58e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EPEMNGIC_00863	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EPEMNGIC_00864	9.92e-265	yacL	-	-	S	-	-	-	domain protein
EPEMNGIC_00865	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPEMNGIC_00866	6.9e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
EPEMNGIC_00867	1.93e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
EPEMNGIC_00868	7.17e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPEMNGIC_00869	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
EPEMNGIC_00870	4.28e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
EPEMNGIC_00871	3.52e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_00872	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPEMNGIC_00873	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
EPEMNGIC_00874	1.54e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EPEMNGIC_00875	1.24e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPEMNGIC_00876	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
EPEMNGIC_00877	6.15e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
EPEMNGIC_00878	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
EPEMNGIC_00880	1.16e-111	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
EPEMNGIC_00881	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
EPEMNGIC_00882	1.58e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EPEMNGIC_00883	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPEMNGIC_00884	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
EPEMNGIC_00885	1.1e-171	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
EPEMNGIC_00886	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
EPEMNGIC_00887	0.0	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_00888	3.81e-144	-	-	-	-	-	-	-	-
EPEMNGIC_00891	4.13e-190	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EPEMNGIC_00892	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
EPEMNGIC_00895	2.64e-92	-	-	-	C	-	-	-	Oxidoreductase
EPEMNGIC_00896	7.39e-82	-	-	-	C	-	-	-	Oxidoreductase
EPEMNGIC_00897	3.02e-80	-	-	-	S	-	-	-	macrophage migration inhibitory factor
EPEMNGIC_00898	1.78e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
EPEMNGIC_00899	8.53e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPEMNGIC_00902	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EPEMNGIC_00903	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EPEMNGIC_00904	6.16e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPEMNGIC_00905	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPEMNGIC_00906	2.68e-252	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EPEMNGIC_00907	6.13e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
EPEMNGIC_00908	5.9e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
EPEMNGIC_00909	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EPEMNGIC_00910	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPEMNGIC_00911	2.3e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
EPEMNGIC_00912	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPEMNGIC_00913	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
EPEMNGIC_00914	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
EPEMNGIC_00915	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EPEMNGIC_00916	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EPEMNGIC_00917	1.43e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
EPEMNGIC_00918	1.89e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
EPEMNGIC_00919	3.47e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPEMNGIC_00920	1.29e-122	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
EPEMNGIC_00921	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
EPEMNGIC_00922	1.91e-196	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
EPEMNGIC_00923	2.65e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
EPEMNGIC_00924	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
EPEMNGIC_00925	1.68e-71	-	-	-	-	-	-	-	-
EPEMNGIC_00926	1.26e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
EPEMNGIC_00927	2.41e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
EPEMNGIC_00928	1.15e-178	-	-	-	-	-	-	-	-
EPEMNGIC_00929	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
EPEMNGIC_00930	1.7e-234	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
EPEMNGIC_00931	7.95e-229	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
EPEMNGIC_00932	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
EPEMNGIC_00933	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
EPEMNGIC_00934	4.99e-58	-	-	-	-	-	-	-	-
EPEMNGIC_00935	8.95e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
EPEMNGIC_00936	8.43e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
EPEMNGIC_00937	4.55e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPEMNGIC_00938	2.08e-48	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
EPEMNGIC_00939	3.03e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
EPEMNGIC_00940	1.18e-179	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EPEMNGIC_00941	4.13e-147	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
EPEMNGIC_00942	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
EPEMNGIC_00943	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPEMNGIC_00944	6.36e-277	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
EPEMNGIC_00945	2.31e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_00946	2.47e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
EPEMNGIC_00948	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
EPEMNGIC_00949	0.0	yhaN	-	-	L	-	-	-	AAA domain
EPEMNGIC_00950	1.42e-270	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
EPEMNGIC_00951	1.4e-63	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
EPEMNGIC_00952	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
EPEMNGIC_00953	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
EPEMNGIC_00954	2.15e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EPEMNGIC_00955	1.65e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EPEMNGIC_00957	1.49e-54	-	-	-	-	-	-	-	-
EPEMNGIC_00958	2.19e-59	-	-	-	-	-	-	-	-
EPEMNGIC_00959	2.47e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
EPEMNGIC_00960	5.53e-132	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
EPEMNGIC_00961	5.27e-281	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
EPEMNGIC_00962	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
EPEMNGIC_00963	6.46e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
EPEMNGIC_00964	2.89e-73	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPEMNGIC_00965	2.57e-90	-	-	-	-	-	-	-	-
EPEMNGIC_00967	9.17e-59	-	-	-	-	-	-	-	-
EPEMNGIC_00968	1.43e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
EPEMNGIC_00969	1.52e-43	-	-	-	-	-	-	-	-
EPEMNGIC_00970	1.63e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPEMNGIC_00971	2.41e-236	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
EPEMNGIC_00972	1.53e-146	-	-	-	-	-	-	-	-
EPEMNGIC_00973	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
EPEMNGIC_00974	3.04e-222	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPEMNGIC_00975	4.4e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
EPEMNGIC_00976	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
EPEMNGIC_00977	3.79e-191	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPEMNGIC_00978	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
EPEMNGIC_00979	8.42e-55	-	-	-	-	-	-	-	-
EPEMNGIC_00980	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
EPEMNGIC_00981	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPEMNGIC_00982	1.97e-124	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
EPEMNGIC_00983	1.81e-61	-	-	-	M	-	-	-	Rib/alpha-like repeat
EPEMNGIC_00984	2.21e-226	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EPEMNGIC_00985	1.52e-267	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
EPEMNGIC_00986	4.41e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
EPEMNGIC_00987	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPEMNGIC_00988	1.49e-229	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
EPEMNGIC_00989	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
EPEMNGIC_00990	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
EPEMNGIC_00991	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
EPEMNGIC_00992	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
EPEMNGIC_00993	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
EPEMNGIC_00994	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
EPEMNGIC_00995	3.91e-91	-	-	-	-	-	-	-	-
EPEMNGIC_00996	5.01e-33	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
EPEMNGIC_00997	6.23e-94	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
EPEMNGIC_00998	2.58e-139	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
EPEMNGIC_00999	1.58e-314	-	-	-	E	-	-	-	amino acid
EPEMNGIC_01000	8.02e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
EPEMNGIC_01002	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EPEMNGIC_01003	1.47e-120	-	-	-	-	-	-	-	-
EPEMNGIC_01004	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPEMNGIC_01005	4.32e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
EPEMNGIC_01006	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
EPEMNGIC_01007	3.1e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
EPEMNGIC_01008	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
EPEMNGIC_01009	1.86e-63	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
EPEMNGIC_01010	1.8e-215	-	-	-	C	-	-	-	Aldo keto reductase
EPEMNGIC_01011	3.7e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
EPEMNGIC_01012	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
EPEMNGIC_01013	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
EPEMNGIC_01014	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
EPEMNGIC_01015	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
EPEMNGIC_01016	7.05e-270	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
EPEMNGIC_01017	3e-221	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
EPEMNGIC_01018	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
EPEMNGIC_01019	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
EPEMNGIC_01020	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPEMNGIC_01021	4.76e-137	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
EPEMNGIC_01023	2.53e-209	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EPEMNGIC_01024	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
EPEMNGIC_01025	8.68e-44	-	-	-	-	-	-	-	-
EPEMNGIC_01026	9.3e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
EPEMNGIC_01027	2.78e-227	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEMNGIC_01028	9.74e-98	-	-	-	O	-	-	-	OsmC-like protein
EPEMNGIC_01030	2.3e-308	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EPEMNGIC_01034	3.52e-176	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EPEMNGIC_01035	4.51e-182	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EPEMNGIC_01039	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
EPEMNGIC_01040	7.07e-65	-	-	-	-	-	-	-	-
EPEMNGIC_01042	8.65e-276	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
EPEMNGIC_01043	4.85e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
EPEMNGIC_01044	2.03e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EPEMNGIC_01045	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
EPEMNGIC_01046	2.05e-187	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPEMNGIC_01047	5.08e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
EPEMNGIC_01048	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
EPEMNGIC_01049	6.23e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
EPEMNGIC_01050	1.1e-125	-	-	-	S	-	-	-	reductase
EPEMNGIC_01051	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPEMNGIC_01052	2.08e-26	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
EPEMNGIC_01053	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
EPEMNGIC_01054	2.46e-289	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
EPEMNGIC_01055	1.46e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
EPEMNGIC_01056	7.14e-193	yycI	-	-	S	-	-	-	YycH protein
EPEMNGIC_01057	8.68e-316	yycH	-	-	S	-	-	-	YycH protein
EPEMNGIC_01058	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
EPEMNGIC_01059	2.6e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
EPEMNGIC_01061	6.43e-204	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
EPEMNGIC_01062	1.39e-82	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
EPEMNGIC_01063	9.31e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
EPEMNGIC_01065	1.38e-158	-	-	-	S	-	-	-	Fic/DOC family
EPEMNGIC_01066	3.08e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
EPEMNGIC_01067	1.57e-71	-	-	-	-	-	-	-	-
EPEMNGIC_01068	8.85e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_01069	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
EPEMNGIC_01070	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
EPEMNGIC_01071	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
EPEMNGIC_01072	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPEMNGIC_01073	8.08e-112	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EPEMNGIC_01074	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
EPEMNGIC_01075	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPEMNGIC_01076	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPEMNGIC_01077	3.44e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPEMNGIC_01078	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
EPEMNGIC_01079	9.9e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPEMNGIC_01080	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPEMNGIC_01081	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
EPEMNGIC_01082	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EPEMNGIC_01083	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EPEMNGIC_01085	7.1e-264	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
EPEMNGIC_01086	3.38e-60	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
EPEMNGIC_01087	2.05e-169	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_01088	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
EPEMNGIC_01090	9.9e-56	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain protein
EPEMNGIC_01093	7.62e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
EPEMNGIC_01094	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EPEMNGIC_01095	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EPEMNGIC_01096	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
EPEMNGIC_01097	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPEMNGIC_01098	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
EPEMNGIC_01099	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
EPEMNGIC_01100	9.23e-116	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
EPEMNGIC_01101	9.53e-206	-	-	-	S	-	-	-	reductase
EPEMNGIC_01103	1.57e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
EPEMNGIC_01104	0.000336	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
EPEMNGIC_01105	1.18e-45	-	-	-	K	-	-	-	LysR substrate binding domain
EPEMNGIC_01107	1.04e-24	-	-	-	S	-	-	-	amidohydrolase
EPEMNGIC_01108	4.27e-291	-	-	-	S	-	-	-	amidohydrolase
EPEMNGIC_01110	1.91e-42	blpT	-	-	-	-	-	-	-
EPEMNGIC_01111	1.08e-53	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EPEMNGIC_01112	1.28e-11	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EPEMNGIC_01113	9.4e-127	-	-	-	L	-	-	-	Helix-turn-helix domain
EPEMNGIC_01114	1.71e-206	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
EPEMNGIC_01115	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
EPEMNGIC_01116	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
EPEMNGIC_01117	6.52e-272	-	-	-	L	-	-	-	Integrase core domain
EPEMNGIC_01118	2.98e-163	-	-	-	O	-	-	-	Bacterial dnaA protein
EPEMNGIC_01120	9.91e-87	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
EPEMNGIC_01121	4.74e-51	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
EPEMNGIC_01123	0.0	snf	-	-	KL	-	-	-	domain protein
EPEMNGIC_01124	1.44e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
EPEMNGIC_01125	4.75e-267	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EPEMNGIC_01126	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
EPEMNGIC_01127	4.33e-137	-	-	-	L	-	-	-	nuclease
EPEMNGIC_01128	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
EPEMNGIC_01129	2.5e-90	-	-	-	-	-	-	-	-
EPEMNGIC_01130	1.23e-134	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
EPEMNGIC_01131	2.19e-155	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPEMNGIC_01132	2.91e-191	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
EPEMNGIC_01133	3.45e-35	-	-	-	-	-	-	-	-
EPEMNGIC_01134	4.41e-124	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EPEMNGIC_01135	2.13e-181	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPEMNGIC_01136	2.37e-177	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
EPEMNGIC_01137	1.63e-298	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
EPEMNGIC_01138	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPEMNGIC_01139	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EPEMNGIC_01140	6.36e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
EPEMNGIC_01141	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
EPEMNGIC_01142	1.2e-59	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
EPEMNGIC_01143	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
EPEMNGIC_01144	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPEMNGIC_01145	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPEMNGIC_01146	1.16e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPEMNGIC_01147	3.65e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
EPEMNGIC_01148	3.09e-85	-	-	-	-	-	-	-	-
EPEMNGIC_01149	4.58e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPEMNGIC_01150	8.1e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPEMNGIC_01151	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
EPEMNGIC_01152	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPEMNGIC_01153	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPEMNGIC_01154	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EPEMNGIC_01155	3.03e-256	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
EPEMNGIC_01156	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
EPEMNGIC_01158	6.77e-77	-	-	-	-	-	-	-	-
EPEMNGIC_01159	1.14e-229	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
EPEMNGIC_01160	5.13e-162	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPEMNGIC_01161	5.61e-71	-	-	-	-	-	-	-	-
EPEMNGIC_01162	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPEMNGIC_01163	1.88e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPEMNGIC_01164	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPEMNGIC_01165	1.64e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
EPEMNGIC_01166	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPEMNGIC_01167	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPEMNGIC_01168	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPEMNGIC_01169	1.11e-260	camS	-	-	S	-	-	-	sex pheromone
EPEMNGIC_01170	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPEMNGIC_01171	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
EPEMNGIC_01172	8.91e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPEMNGIC_01173	2.36e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPEMNGIC_01174	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
EPEMNGIC_01175	4.46e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
EPEMNGIC_01176	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
EPEMNGIC_01177	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPEMNGIC_01178	4.31e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPEMNGIC_01179	8.27e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPEMNGIC_01180	6.13e-198	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPEMNGIC_01181	2.47e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EPEMNGIC_01182	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
EPEMNGIC_01183	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPEMNGIC_01184	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPEMNGIC_01185	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPEMNGIC_01186	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
EPEMNGIC_01187	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPEMNGIC_01188	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPEMNGIC_01189	1.66e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPEMNGIC_01190	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
EPEMNGIC_01191	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
EPEMNGIC_01192	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPEMNGIC_01193	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPEMNGIC_01194	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPEMNGIC_01195	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPEMNGIC_01196	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPEMNGIC_01197	5.22e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPEMNGIC_01198	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPEMNGIC_01199	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPEMNGIC_01200	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
EPEMNGIC_01201	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPEMNGIC_01202	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPEMNGIC_01203	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPEMNGIC_01204	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPEMNGIC_01205	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPEMNGIC_01206	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPEMNGIC_01207	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
EPEMNGIC_01208	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPEMNGIC_01209	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
EPEMNGIC_01210	5.1e-186	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
EPEMNGIC_01211	7.05e-45	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
EPEMNGIC_01218	3.09e-23	-	-	-	M	ko:K21449	-	ko00000,ko02000	Phage minor structural protein
EPEMNGIC_01219	1.75e-175	-	-	-	M	-	-	-	Prophage endopeptidase tail
EPEMNGIC_01220	7.93e-104	-	-	-	S	-	-	-	Phage tail protein
EPEMNGIC_01221	2.62e-76	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
EPEMNGIC_01222	5.11e-248	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
EPEMNGIC_01223	5.82e-13	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
EPEMNGIC_01224	1.25e-99	-	-	-	S	-	-	-	Phage tail tube protein
EPEMNGIC_01228	6.4e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
EPEMNGIC_01229	2.28e-217	-	-	-	S	-	-	-	Phage capsid family
EPEMNGIC_01230	2.25e-82	-	-	-	S	-	-	-	Clp protease
EPEMNGIC_01231	2.71e-247	-	-	-	S	-	-	-	Phage portal protein
EPEMNGIC_01232	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
EPEMNGIC_01233	1.49e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
EPEMNGIC_01234	5.98e-105	-	-	-	L	-	-	-	HNH nucleases
EPEMNGIC_01236	4.14e-09	-	-	-	-	-	-	-	-
EPEMNGIC_01238	3.15e-108	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
EPEMNGIC_01242	7.59e-17	-	-	-	-	-	-	-	-
EPEMNGIC_01246	4.57e-164	-	-	-	-	-	-	-	-
EPEMNGIC_01248	2.8e-92	-	-	-	-	-	-	-	-
EPEMNGIC_01250	1.37e-48	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
EPEMNGIC_01252	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EPEMNGIC_01253	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
EPEMNGIC_01254	1.91e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPEMNGIC_01255	5.98e-55	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
EPEMNGIC_01256	5.93e-281	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
EPEMNGIC_01257	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EPEMNGIC_01258	4.65e-195	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
EPEMNGIC_01259	5.74e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPEMNGIC_01260	1.06e-139	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EPEMNGIC_01261	2.05e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
EPEMNGIC_01262	4.59e-36	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EPEMNGIC_01263	3.18e-125	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EPEMNGIC_01264	5.22e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
EPEMNGIC_01265	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
EPEMNGIC_01266	1.75e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01267	5.77e-140	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EPEMNGIC_01268	2.16e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
EPEMNGIC_01269	4.52e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_01270	1.58e-110	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
EPEMNGIC_01271	1.43e-271	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EPEMNGIC_01272	0.0	cadA	-	-	P	-	-	-	P-type ATPase
EPEMNGIC_01273	1.31e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
EPEMNGIC_01274	1.75e-161	-	-	-	-	-	-	-	-
EPEMNGIC_01275	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
EPEMNGIC_01276	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
EPEMNGIC_01278	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
EPEMNGIC_01279	9.58e-112	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
EPEMNGIC_01280	9.77e-230	ydhF	-	-	S	-	-	-	Aldo keto reductase
EPEMNGIC_01281	4.72e-206	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
EPEMNGIC_01282	4.18e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
EPEMNGIC_01283	1.06e-161	XK27_10500	-	-	K	-	-	-	response regulator
EPEMNGIC_01284	2.4e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
EPEMNGIC_01285	2.04e-173	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01286	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
EPEMNGIC_01287	9.11e-198	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
EPEMNGIC_01288	1.4e-208	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
EPEMNGIC_01289	2.6e-39	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
EPEMNGIC_01290	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EPEMNGIC_01291	2.85e-250	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_01292	1.6e-117	ymdB	-	-	S	-	-	-	Macro domain protein
EPEMNGIC_01293	1.51e-137	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
EPEMNGIC_01294	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
EPEMNGIC_01295	1.21e-63	-	-	-	-	-	-	-	-
EPEMNGIC_01296	6.86e-294	-	-	-	S	-	-	-	Putative metallopeptidase domain
EPEMNGIC_01297	1.33e-257	-	-	-	S	-	-	-	associated with various cellular activities
EPEMNGIC_01298	6.7e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
EPEMNGIC_01299	9.94e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
EPEMNGIC_01301	7.61e-148	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
EPEMNGIC_01302	3.32e-72	-	-	-	-	-	-	-	-
EPEMNGIC_01304	3.17e-71	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
EPEMNGIC_01305	6.8e-73	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
EPEMNGIC_01306	2.04e-65	-	-	-	-	-	-	-	-
EPEMNGIC_01307	1.39e-257	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
EPEMNGIC_01308	1.28e-293	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
EPEMNGIC_01309	1.24e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EPEMNGIC_01310	8.51e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
EPEMNGIC_01311	1.35e-87	-	-	-	S	-	-	-	Putative ABC-transporter type IV
EPEMNGIC_01312	8.57e-44	-	-	-	S	-	-	-	Putative ABC-transporter type IV
EPEMNGIC_01313	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
EPEMNGIC_01314	1.03e-184	-	-	-	-	-	-	-	-
EPEMNGIC_01316	2.48e-310	-	-	-	M	-	-	-	Glycosyl transferase
EPEMNGIC_01317	2.33e-287	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
EPEMNGIC_01318	3.99e-181	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
EPEMNGIC_01319	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
EPEMNGIC_01320	1.59e-303	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
EPEMNGIC_01321	3.26e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
EPEMNGIC_01322	1.08e-113	-	-	-	Q	-	-	-	Methyltransferase
EPEMNGIC_01323	5.18e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
EPEMNGIC_01324	2.81e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
EPEMNGIC_01325	2.92e-204	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
EPEMNGIC_01326	6.31e-32	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EPEMNGIC_01327	1.1e-218	-	-	-	S	-	-	-	Conserved hypothetical protein 698
EPEMNGIC_01328	1.6e-211	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
EPEMNGIC_01329	1.27e-140	-	-	-	I	-	-	-	alpha/beta hydrolase fold
EPEMNGIC_01330	7.04e-104	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
EPEMNGIC_01331	5.66e-29	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
EPEMNGIC_01332	2.1e-218	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
EPEMNGIC_01333	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
EPEMNGIC_01334	0.0	arcT	-	-	E	-	-	-	Dipeptidase
EPEMNGIC_01335	8.01e-72	-	-	-	Q	-	-	-	Methyltransferase
EPEMNGIC_01336	6.29e-193	nikA	-	-	E	ko:K15584	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Nickel ABC transporter
EPEMNGIC_01337	2.84e-56	-	-	-	P	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
EPEMNGIC_01338	1.51e-68	-	-	-	P	-	-	-	ABC transporter, permease protein
EPEMNGIC_01343	6.97e-35	-	-	-	-	-	-	-	-
EPEMNGIC_01348	2.23e-20	-	-	-	-	-	-	-	-
EPEMNGIC_01349	3.72e-104	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
EPEMNGIC_01353	2.31e-21	-	-	-	-	-	-	-	-
EPEMNGIC_01358	1.18e-50	-	-	-	S	-	-	-	ORF6C domain
EPEMNGIC_01362	1.9e-31	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
EPEMNGIC_01363	5.58e-83	-	-	-	S	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
EPEMNGIC_01364	4.55e-172	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
EPEMNGIC_01368	3.3e-43	-	-	-	-	-	-	-	-
EPEMNGIC_01369	2.02e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EPEMNGIC_01370	4.31e-30	-	-	-	-	-	-	-	-
EPEMNGIC_01375	0.000118	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
EPEMNGIC_01376	1.39e-32	-	-	-	K	-	-	-	Helix-turn-helix domain
EPEMNGIC_01379	1.28e-141	-	-	-	J	-	-	-	Domain of unknown function (DUF4041)
EPEMNGIC_01380	6.29e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_01381	3.39e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
EPEMNGIC_01382	1.57e-150	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EPEMNGIC_01383	3.39e-293	-	-	-	P	-	-	-	Chloride transporter, ClC family
EPEMNGIC_01384	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
EPEMNGIC_01385	2.3e-142	-	-	-	I	-	-	-	Acid phosphatase homologues
EPEMNGIC_01396	9.22e-74	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
EPEMNGIC_01397	1.92e-162	-	-	-	S	-	-	-	Tetratricopeptide repeat
EPEMNGIC_01398	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPEMNGIC_01399	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPEMNGIC_01400	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPEMNGIC_01401	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
EPEMNGIC_01402	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
EPEMNGIC_01403	2.44e-20	-	-	-	-	-	-	-	-
EPEMNGIC_01404	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPEMNGIC_01405	3.8e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPEMNGIC_01406	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EPEMNGIC_01407	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
EPEMNGIC_01408	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
EPEMNGIC_01409	2.52e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPEMNGIC_01410	3.77e-123	-	-	-	-	-	-	-	-
EPEMNGIC_01412	4.88e-162	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPEMNGIC_01413	4.08e-270	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
EPEMNGIC_01414	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPEMNGIC_01415	2.22e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
EPEMNGIC_01416	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
EPEMNGIC_01417	1.3e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
EPEMNGIC_01418	1.69e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
EPEMNGIC_01419	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
EPEMNGIC_01420	2.8e-231	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEMNGIC_01421	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
EPEMNGIC_01422	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPEMNGIC_01423	1.81e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
EPEMNGIC_01424	1.72e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPEMNGIC_01425	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
EPEMNGIC_01426	1.07e-112	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
EPEMNGIC_01427	7.99e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
EPEMNGIC_01428	8.51e-148	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01429	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01430	3.96e-49	-	-	-	-	-	-	-	-
EPEMNGIC_01431	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
EPEMNGIC_01432	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
EPEMNGIC_01433	3.11e-220	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
EPEMNGIC_01434	2.6e-33	-	-	-	-	-	-	-	-
EPEMNGIC_01435	2.43e-145	-	-	-	-	-	-	-	-
EPEMNGIC_01436	1.23e-273	yttB	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_01437	5.38e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
EPEMNGIC_01438	8.57e-114	-	-	-	-	-	-	-	-
EPEMNGIC_01439	2.91e-140	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
EPEMNGIC_01440	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
EPEMNGIC_01441	2.61e-19	-	-	-	-	-	-	-	-
EPEMNGIC_01442	2.72e-157	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
EPEMNGIC_01444	3.08e-128	-	-	-	-	-	-	-	-
EPEMNGIC_01445	8.39e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
EPEMNGIC_01446	1.87e-176	-	-	-	S	-	-	-	Alpha beta hydrolase
EPEMNGIC_01447	3.46e-265	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
EPEMNGIC_01448	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EPEMNGIC_01449	1.57e-46	-	-	-	-	-	-	-	-
EPEMNGIC_01450	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
EPEMNGIC_01451	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
EPEMNGIC_01452	3.3e-152	-	-	-	M	-	-	-	Bacterial sugar transferase
EPEMNGIC_01453	1.09e-222	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
EPEMNGIC_01454	3.17e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
EPEMNGIC_01455	2.02e-175	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
EPEMNGIC_01456	7.27e-42	-	-	-	-	-	-	-	-
EPEMNGIC_01457	8.54e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
EPEMNGIC_01458	1.83e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
EPEMNGIC_01459	0.0	potE	-	-	E	-	-	-	Amino Acid
EPEMNGIC_01460	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
EPEMNGIC_01461	1.39e-280	arcT	-	-	E	-	-	-	Aminotransferase
EPEMNGIC_01462	1.42e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
EPEMNGIC_01463	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
EPEMNGIC_01464	1.73e-97	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
EPEMNGIC_01465	1e-72	-	-	-	-	-	-	-	-
EPEMNGIC_01466	4.92e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
EPEMNGIC_01468	1.91e-297	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
EPEMNGIC_01469	1.03e-242	mocA	-	-	S	-	-	-	Oxidoreductase
EPEMNGIC_01470	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
EPEMNGIC_01471	6.95e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
EPEMNGIC_01472	1.25e-211	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
EPEMNGIC_01473	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
EPEMNGIC_01474	1.64e-242	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
EPEMNGIC_01475	4.19e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
EPEMNGIC_01476	9.21e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
EPEMNGIC_01477	1.7e-26	-	-	-	-	-	-	-	-
EPEMNGIC_01478	2.2e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
EPEMNGIC_01479	1.16e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
EPEMNGIC_01480	1.28e-186	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
EPEMNGIC_01481	1.18e-24	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
EPEMNGIC_01482	7.86e-34	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
EPEMNGIC_01483	2.6e-150	pnb	-	-	C	-	-	-	nitroreductase
EPEMNGIC_01484	1.23e-49	-	-	-	-	-	-	-	-
EPEMNGIC_01485	8.93e-307	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
EPEMNGIC_01486	2.93e-112	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
EPEMNGIC_01488	6.57e-63	-	-	-	-	-	-	-	-
EPEMNGIC_01489	4.16e-198	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPEMNGIC_01490	8.27e-189	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
EPEMNGIC_01491	8.81e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
EPEMNGIC_01492	4.65e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
EPEMNGIC_01494	1.04e-222	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
EPEMNGIC_01495	3.5e-91	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EPEMNGIC_01496	1.62e-67	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPEMNGIC_01497	1.67e-58	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01498	5.19e-35	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01499	5.67e-70	-	-	-	S	-	-	-	Belongs to the HesB IscA family
EPEMNGIC_01500	3.78e-23	-	-	-	-	-	-	-	-
EPEMNGIC_01501	6.13e-27	-	-	-	-	-	-	-	-
EPEMNGIC_01502	1.56e-31	-	-	-	-	-	-	-	-
EPEMNGIC_01503	6.9e-25	-	-	-	K	-	-	-	LytTr DNA-binding domain
EPEMNGIC_01504	5.04e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
EPEMNGIC_01505	1.84e-104	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
EPEMNGIC_01506	4.11e-85	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPEMNGIC_01508	3.96e-76	-	-	-	-	-	-	-	-
EPEMNGIC_01509	2.23e-94	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
EPEMNGIC_01510	4.45e-67	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
EPEMNGIC_01511	1.99e-66	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
EPEMNGIC_01512	1.5e-243	-	-	-	L	-	-	-	Transposase
EPEMNGIC_01513	1.56e-96	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
EPEMNGIC_01514	4.43e-43	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
EPEMNGIC_01515	5.16e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
EPEMNGIC_01516	8e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
EPEMNGIC_01517	1.09e-122	dpsB	-	-	P	-	-	-	Belongs to the Dps family
EPEMNGIC_01518	7.25e-44	-	-	-	C	-	-	-	Heavy-metal-associated domain
EPEMNGIC_01519	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
EPEMNGIC_01520	1.76e-133	-	-	-	-	-	-	-	-
EPEMNGIC_01521	2.46e-137	-	-	-	L	-	-	-	Bacterial dnaA protein
EPEMNGIC_01523	9.41e-222	-	-	-	L	-	-	-	Integrase core domain
EPEMNGIC_01524	3.38e-27	-	-	-	L	-	-	-	Integrase core domain
EPEMNGIC_01525	9.19e-88	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_01526	0.0	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
EPEMNGIC_01527	4.29e-74	-	-	-	-	-	-	-	-
EPEMNGIC_01528	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPEMNGIC_01530	1.79e-42	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
EPEMNGIC_01531	2.16e-28	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
EPEMNGIC_01532	9.84e-132	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
EPEMNGIC_01533	1.58e-310	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
EPEMNGIC_01534	9.89e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
EPEMNGIC_01535	4.68e-233	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPEMNGIC_01537	1.45e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
EPEMNGIC_01538	1.29e-53	-	-	-	S	-	-	-	Cytochrome B5
EPEMNGIC_01539	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
EPEMNGIC_01540	9.37e-52	-	-	-	S	-	-	-	Cytochrome B5
EPEMNGIC_01541	1.99e-50	-	-	-	S	ko:K02348	-	ko00000	Gnat family
EPEMNGIC_01542	6.12e-11	-	-	-	S	ko:K02348	-	ko00000	Gnat family
EPEMNGIC_01543	2e-14	-	-	-	GM	-	-	-	NmrA-like family
EPEMNGIC_01544	4.55e-68	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EPEMNGIC_01545	1.3e-137	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
EPEMNGIC_01546	2.25e-100	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
EPEMNGIC_01547	2.18e-289	-	-	-	-	-	-	-	-
EPEMNGIC_01548	1.32e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
EPEMNGIC_01549	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
EPEMNGIC_01550	1.97e-143	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
EPEMNGIC_01551	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
EPEMNGIC_01552	9.85e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
EPEMNGIC_01553	2.72e-38	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
EPEMNGIC_01554	3.51e-253	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
EPEMNGIC_01555	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
EPEMNGIC_01557	4.89e-167	-	-	-	F	-	-	-	glutamine amidotransferase
EPEMNGIC_01558	1.61e-81	-	-	-	-	-	-	-	-
EPEMNGIC_01559	1.29e-201	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
EPEMNGIC_01560	2.39e-196	-	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_01561	4.68e-234	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
EPEMNGIC_01562	6.71e-220	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
EPEMNGIC_01563	3.15e-115	-	-	-	K	-	-	-	Virulence activator alpha C-term
EPEMNGIC_01564	4.68e-119	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
EPEMNGIC_01565	6.18e-51	-	-	-	C	-	-	-	Flavodoxin
EPEMNGIC_01566	8.91e-146	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
EPEMNGIC_01567	5.58e-70	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
EPEMNGIC_01568	1.94e-13	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
EPEMNGIC_01569	3.15e-141	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
EPEMNGIC_01570	1.32e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
EPEMNGIC_01571	4.25e-306	-	-	-	T	-	-	-	GHKL domain
EPEMNGIC_01572	3.03e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
EPEMNGIC_01573	9.98e-56	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
EPEMNGIC_01575	1.45e-10	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
EPEMNGIC_01578	6.41e-163	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
EPEMNGIC_01579	5.09e-153	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
EPEMNGIC_01580	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EPEMNGIC_01581	9.98e-24	-	-	-	-	-	-	-	-
EPEMNGIC_01582	3.56e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
EPEMNGIC_01583	6.28e-116	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
EPEMNGIC_01584	1.03e-96	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPEMNGIC_01585	9.27e-245	flp	-	-	V	-	-	-	Beta-lactamase
EPEMNGIC_01586	4.83e-118	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
EPEMNGIC_01587	2.21e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
EPEMNGIC_01588	4.04e-87	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
EPEMNGIC_01589	1.13e-40	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
EPEMNGIC_01591	8.34e-147	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
EPEMNGIC_01592	2.43e-142	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
EPEMNGIC_01594	3.48e-100	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
EPEMNGIC_01595	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
EPEMNGIC_01596	1.02e-66	-	-	-	-	-	-	-	-
EPEMNGIC_01597	1.15e-172	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPEMNGIC_01599	3.9e-14	-	-	-	-	-	-	-	-
EPEMNGIC_01601	4.76e-114	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
EPEMNGIC_01602	7.31e-56	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
EPEMNGIC_01603	8.03e-71	-	-	-	S	-	-	-	Bacteriophage holin family
EPEMNGIC_01604	3.1e-74	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
EPEMNGIC_01607	7.84e-234	-	-	-	S	-	-	-	Peptidase family M23
EPEMNGIC_01608	3.05e-120	-	-	-	S	-	-	-	Phage tail protein
EPEMNGIC_01609	0.0	-	-	-	D	-	-	-	domain protein
EPEMNGIC_01610	3.01e-120	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
EPEMNGIC_01611	2.42e-154	-	-	-	-	-	-	-	-
EPEMNGIC_01612	1.35e-92	-	-	-	-	-	-	-	-
EPEMNGIC_01613	1.17e-124	-	-	-	-	-	-	-	-
EPEMNGIC_01614	1.54e-67	-	-	-	-	-	-	-	-
EPEMNGIC_01615	1.04e-82	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
EPEMNGIC_01616	1.96e-252	gpG	-	-	-	-	-	-	-
EPEMNGIC_01617	1.73e-119	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
EPEMNGIC_01618	1.92e-229	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
EPEMNGIC_01619	4.37e-39	-	-	-	-	-	-	-	-
EPEMNGIC_01620	1.76e-231	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
EPEMNGIC_01621	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
EPEMNGIC_01622	8.99e-104	-	-	-	-	-	-	-	-
EPEMNGIC_01623	2.38e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPEMNGIC_01624	9.95e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
EPEMNGIC_01625	1.9e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
EPEMNGIC_01626	1.06e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EPEMNGIC_01627	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
EPEMNGIC_01628	7.04e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
EPEMNGIC_01629	4.1e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
EPEMNGIC_01630	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
EPEMNGIC_01631	1.85e-284	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
EPEMNGIC_01632	5.05e-57	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
EPEMNGIC_01633	3.23e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
EPEMNGIC_01634	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPEMNGIC_01635	1.82e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
EPEMNGIC_01636	1.97e-137	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
EPEMNGIC_01637	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
EPEMNGIC_01638	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
EPEMNGIC_01639	1.32e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
EPEMNGIC_01640	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
EPEMNGIC_01641	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPEMNGIC_01642	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPEMNGIC_01643	0.0	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_01644	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
EPEMNGIC_01645	1.65e-301	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
EPEMNGIC_01646	2.38e-134	-	-	-	V	-	-	-	VanZ like family
EPEMNGIC_01647	7.03e-33	-	-	-	-	-	-	-	-
EPEMNGIC_01648	4.13e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
EPEMNGIC_01649	6.26e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EPEMNGIC_01650	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
EPEMNGIC_01651	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
EPEMNGIC_01652	3.69e-196	yeaE	-	-	S	-	-	-	Aldo keto
EPEMNGIC_01653	3.25e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
EPEMNGIC_01654	4.03e-211	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
EPEMNGIC_01655	2.95e-192	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
EPEMNGIC_01656	1.1e-131	-	-	-	M	-	-	-	LysM domain protein
EPEMNGIC_01657	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
EPEMNGIC_01658	1.73e-151	-	-	-	M	-	-	-	LysM domain protein
EPEMNGIC_01659	7.03e-192	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
EPEMNGIC_01660	9.29e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPEMNGIC_01661	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
EPEMNGIC_01662	1.34e-258	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
EPEMNGIC_01663	2.78e-276	isp	-	-	L	-	-	-	Transposase
EPEMNGIC_01664	5.6e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
EPEMNGIC_01665	3.68e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
EPEMNGIC_01666	9.35e-152	-	-	-	I	-	-	-	phosphatase
EPEMNGIC_01668	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
EPEMNGIC_01669	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
EPEMNGIC_01675	1.19e-231	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
EPEMNGIC_01676	5.17e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
EPEMNGIC_01677	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
EPEMNGIC_01678	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EPEMNGIC_01679	1.21e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
EPEMNGIC_01680	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPEMNGIC_01681	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPEMNGIC_01682	1.13e-48	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
EPEMNGIC_01683	1.03e-203	rssA	-	-	S	-	-	-	Phospholipase, patatin family
EPEMNGIC_01684	1.63e-152	-	-	-	L	-	-	-	Integrase
EPEMNGIC_01685	7.34e-194	-	-	-	EG	-	-	-	EamA-like transporter family
EPEMNGIC_01686	6.65e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
EPEMNGIC_01687	2.34e-127	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
EPEMNGIC_01688	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
EPEMNGIC_01689	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
EPEMNGIC_01690	2e-240	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
EPEMNGIC_01691	1.78e-102	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
EPEMNGIC_01692	1.8e-290	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
EPEMNGIC_01693	2.28e-108	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
EPEMNGIC_01694	4.78e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
EPEMNGIC_01695	6.37e-60	-	-	-	-	-	-	-	-
EPEMNGIC_01696	1.77e-240	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
EPEMNGIC_01697	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
EPEMNGIC_01698	3.11e-26	-	-	-	-	-	-	-	-
EPEMNGIC_01699	2.6e-232	-	-	-	-	-	-	-	-
EPEMNGIC_01700	1.12e-211	-	-	-	H	-	-	-	geranyltranstransferase activity
EPEMNGIC_01701	3.17e-280	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
EPEMNGIC_01702	9.9e-49	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
EPEMNGIC_01703	2.29e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
EPEMNGIC_01704	1.79e-101	-	-	-	S	-	-	-	Flavodoxin
EPEMNGIC_01708	1.02e-277	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
EPEMNGIC_01709	5.9e-74	-	-	-	-	-	-	-	-
EPEMNGIC_01711	4.26e-35	-	-	-	-	-	-	-	-
EPEMNGIC_01712	1.04e-238	-	-	-	U	-	-	-	type IV secretory pathway VirB4
EPEMNGIC_01714	6.21e-31	-	-	-	S	-	-	-	Peptidase family M23
EPEMNGIC_01720	0.0	-	-	-	M	-	-	-	NlpC/P60 family
EPEMNGIC_01721	0.0	-	-	-	S	-	-	-	Peptidase, M23
EPEMNGIC_01722	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
EPEMNGIC_01723	1.3e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01724	9.18e-145	-	-	-	-	-	-	-	-
EPEMNGIC_01725	9.48e-183	-	-	-	G	-	-	-	MucBP domain
EPEMNGIC_01726	1.75e-127	-	-	-	S	-	-	-	Pfam:DUF3816
EPEMNGIC_01727	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
EPEMNGIC_01728	5.62e-37	-	-	-	-	-	-	-	-
EPEMNGIC_01729	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
EPEMNGIC_01730	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPEMNGIC_01731	2.1e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
EPEMNGIC_01732	7.98e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
EPEMNGIC_01733	5.39e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EPEMNGIC_01734	1.97e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
EPEMNGIC_01735	9.13e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
EPEMNGIC_01736	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
EPEMNGIC_01737	8.86e-317	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
EPEMNGIC_01738	2.37e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
EPEMNGIC_01739	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EPEMNGIC_01740	8.21e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
EPEMNGIC_01741	1.95e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
EPEMNGIC_01742	4.41e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
EPEMNGIC_01743	2.54e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
EPEMNGIC_01744	6.33e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
EPEMNGIC_01745	7.02e-122	-	-	-	P	-	-	-	Cadmium resistance transporter
EPEMNGIC_01746	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01747	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
EPEMNGIC_01748	3.69e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
EPEMNGIC_01749	6.29e-170	-	-	-	M	-	-	-	PFAM NLP P60 protein
EPEMNGIC_01751	1.54e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
EPEMNGIC_01752	2.58e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
EPEMNGIC_01753	1.06e-104	-	-	-	S	-	-	-	Cupin domain
EPEMNGIC_01754	6.68e-98	-	-	-	S	-	-	-	UPF0756 membrane protein
EPEMNGIC_01755	9.25e-306	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
EPEMNGIC_01756	9.74e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
EPEMNGIC_01757	2.75e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
EPEMNGIC_01758	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
EPEMNGIC_01759	2.72e-174	-	-	-	S	-	-	-	DUF218 domain
EPEMNGIC_01760	4.81e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPEMNGIC_01761	1.99e-73	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPEMNGIC_01762	5.16e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPEMNGIC_01763	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
EPEMNGIC_01764	5.85e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
EPEMNGIC_01765	1.09e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
EPEMNGIC_01766	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPEMNGIC_01768	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
EPEMNGIC_01770	1.06e-276	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
EPEMNGIC_01771	9.52e-124	-	-	-	S	-	-	-	AmiS/UreI family transporter
EPEMNGIC_01772	4.88e-60	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
EPEMNGIC_01773	2.83e-84	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
EPEMNGIC_01774	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
EPEMNGIC_01775	2.54e-101	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EPEMNGIC_01776	1.97e-168	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EPEMNGIC_01777	3.44e-146	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EPEMNGIC_01778	9.18e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EPEMNGIC_01779	2.34e-55	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPEMNGIC_01780	4.2e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPEMNGIC_01781	5.49e-237	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
EPEMNGIC_01782	5.52e-182	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
EPEMNGIC_01783	9.42e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPEMNGIC_01784	7.17e-171	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
EPEMNGIC_01785	2.14e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
EPEMNGIC_01786	1.86e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
EPEMNGIC_01787	7.4e-197	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
EPEMNGIC_01788	4.47e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPEMNGIC_01789	2.89e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
EPEMNGIC_01790	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
EPEMNGIC_01791	5.53e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPEMNGIC_01792	1.45e-257	-	-	-	-	-	-	-	-
EPEMNGIC_01793	7.19e-68	-	-	-	-	-	-	-	-
EPEMNGIC_01794	1.21e-48	-	-	-	-	-	-	-	-
EPEMNGIC_01795	7.88e-121	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
EPEMNGIC_01796	9.06e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
EPEMNGIC_01797	3.14e-226	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
EPEMNGIC_01798	2.54e-288	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EPEMNGIC_01799	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
EPEMNGIC_01800	6.6e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
EPEMNGIC_01801	2.56e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
EPEMNGIC_01802	2.14e-296	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPEMNGIC_01803	5.66e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
EPEMNGIC_01804	2.32e-104	usp5	-	-	T	-	-	-	universal stress protein
EPEMNGIC_01805	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
EPEMNGIC_01806	4.85e-52	-	-	-	-	-	-	-	-
EPEMNGIC_01807	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPEMNGIC_01808	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPEMNGIC_01809	1.7e-242	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
EPEMNGIC_01810	1.06e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
EPEMNGIC_01811	4e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
EPEMNGIC_01812	4.1e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
EPEMNGIC_01813	2.31e-197	-	-	-	V	-	-	-	(ABC) transporter
EPEMNGIC_01814	1.63e-116	-	-	-	GM	-	-	-	epimerase
EPEMNGIC_01815	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
EPEMNGIC_01816	4.73e-102	yybA	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_01817	6.1e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
EPEMNGIC_01818	1.87e-236	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
EPEMNGIC_01819	1.77e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
EPEMNGIC_01820	2.34e-187	-	-	-	-	-	-	-	-
EPEMNGIC_01821	1.7e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
EPEMNGIC_01822	1.16e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEMNGIC_01823	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01824	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
EPEMNGIC_01825	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
EPEMNGIC_01826	2e-114	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPEMNGIC_01827	5.01e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
EPEMNGIC_01828	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
EPEMNGIC_01829	7.11e-309	-	-	-	E	-	-	-	amino acid
EPEMNGIC_01830	9.06e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
EPEMNGIC_01831	8.01e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
EPEMNGIC_01832	1.79e-212	-	-	-	GK	-	-	-	ROK family
EPEMNGIC_01833	0.0	fusA1	-	-	J	-	-	-	elongation factor G
EPEMNGIC_01834	4.32e-105	uspA3	-	-	T	-	-	-	universal stress protein
EPEMNGIC_01835	8.24e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
EPEMNGIC_01836	1.78e-83	-	-	-	-	-	-	-	-
EPEMNGIC_01837	3.18e-11	-	-	-	-	-	-	-	-
EPEMNGIC_01838	7e-153	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
EPEMNGIC_01839	1.59e-175	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
EPEMNGIC_01840	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
EPEMNGIC_01841	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
EPEMNGIC_01842	3.39e-49	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
EPEMNGIC_01843	4.45e-81	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
EPEMNGIC_01844	7.31e-43	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
EPEMNGIC_01845	2e-206	-	-	-	-	-	-	-	-
EPEMNGIC_01846	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
EPEMNGIC_01847	8.47e-240	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
EPEMNGIC_01848	1.28e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
EPEMNGIC_01849	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
EPEMNGIC_01850	6.5e-71	-	-	-	-	-	-	-	-
EPEMNGIC_01851	8.69e-149	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
EPEMNGIC_01852	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01853	8.95e-129	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
EPEMNGIC_01854	1.03e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
EPEMNGIC_01855	4.47e-177	-	-	-	IQ	-	-	-	KR domain
EPEMNGIC_01856	2.71e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
EPEMNGIC_01857	2.41e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
EPEMNGIC_01858	3.04e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
EPEMNGIC_01859	8.81e-317	yagE	-	-	E	-	-	-	amino acid
EPEMNGIC_01860	1.19e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
EPEMNGIC_01861	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
EPEMNGIC_01862	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
EPEMNGIC_01863	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EPEMNGIC_01864	2.94e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EPEMNGIC_01865	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EPEMNGIC_01866	3.64e-182	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
EPEMNGIC_01867	1.47e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
EPEMNGIC_01868	4.14e-295	-	-	-	-	-	-	-	-
EPEMNGIC_01869	1.3e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
EPEMNGIC_01870	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
EPEMNGIC_01871	1.78e-97	-	-	-	F	-	-	-	Nudix hydrolase
EPEMNGIC_01872	9.66e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
EPEMNGIC_01873	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
EPEMNGIC_01874	1.83e-33	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
EPEMNGIC_01875	3.82e-192	-	-	-	-	-	-	-	-
EPEMNGIC_01876	2.91e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
EPEMNGIC_01877	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
EPEMNGIC_01878	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
EPEMNGIC_01879	7.72e-231	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPEMNGIC_01880	6.08e-13	-	-	-	S	-	-	-	CsbD-like
EPEMNGIC_01881	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
EPEMNGIC_01882	8.76e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPEMNGIC_01883	4.71e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
EPEMNGIC_01884	1.56e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
EPEMNGIC_01885	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
EPEMNGIC_01886	3.82e-311	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
EPEMNGIC_01887	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
EPEMNGIC_01888	2.15e-203	-	-	-	EG	-	-	-	EamA-like transporter family
EPEMNGIC_01889	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
EPEMNGIC_01890	9.72e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
EPEMNGIC_01891	4.06e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
EPEMNGIC_01893	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
EPEMNGIC_01894	1.16e-112	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EPEMNGIC_01895	5.01e-172	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
EPEMNGIC_01896	7.99e-61	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
EPEMNGIC_01897	8.54e-13	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
EPEMNGIC_01900	6.33e-19	-	-	-	K	-	-	-	ORF6N domain
EPEMNGIC_01901	1.51e-34	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
EPEMNGIC_01904	8.88e-71	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
EPEMNGIC_01906	1.75e-243	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EPEMNGIC_01907	2.86e-286	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EPEMNGIC_01908	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPEMNGIC_01909	4.47e-199	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
EPEMNGIC_01910	3.53e-269	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
EPEMNGIC_01911	1.71e-246	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
EPEMNGIC_01912	1.77e-205	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
EPEMNGIC_01913	5.31e-139	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
EPEMNGIC_01914	4.24e-52	-	-	-	M	-	-	-	family 8
EPEMNGIC_01916	5.87e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPEMNGIC_01917	7.3e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
EPEMNGIC_01918	3.55e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
EPEMNGIC_01920	1.69e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPEMNGIC_01921	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
EPEMNGIC_01922	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
EPEMNGIC_01923	3.83e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
EPEMNGIC_01924	9.51e-51	-	-	-	-	-	-	-	-
EPEMNGIC_01925	3e-168	-	-	-	IQ	-	-	-	dehydrogenase reductase
EPEMNGIC_01926	3.51e-308	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
EPEMNGIC_01929	3.9e-265	isp	-	-	L	-	-	-	Transposase
EPEMNGIC_01932	1.8e-127	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPEMNGIC_01933	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
EPEMNGIC_01934	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPEMNGIC_01935	1.15e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
EPEMNGIC_01936	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPEMNGIC_01937	9.26e-193	-	-	-	S	-	-	-	Helix-turn-helix domain
EPEMNGIC_01938	4.81e-316	ymfH	-	-	S	-	-	-	Peptidase M16
EPEMNGIC_01939	1.67e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
EPEMNGIC_01940	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
EPEMNGIC_01941	1.02e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
EPEMNGIC_01942	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
EPEMNGIC_01943	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
EPEMNGIC_01944	1.1e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
EPEMNGIC_01945	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
EPEMNGIC_01946	1.41e-155	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
EPEMNGIC_01947	1.72e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
EPEMNGIC_01948	3.23e-75	-	-	-	S	-	-	-	Small secreted protein
EPEMNGIC_01949	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
EPEMNGIC_01950	4.68e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EPEMNGIC_01951	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
EPEMNGIC_01952	1.07e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
EPEMNGIC_01953	1.44e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
EPEMNGIC_01954	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPEMNGIC_01955	1.57e-194	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EPEMNGIC_01956	3.99e-127	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPEMNGIC_01957	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPEMNGIC_01958	2.08e-302	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
EPEMNGIC_01959	7.06e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
EPEMNGIC_01960	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPEMNGIC_01961	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
EPEMNGIC_01962	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPEMNGIC_01963	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPEMNGIC_01965	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
EPEMNGIC_01966	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
EPEMNGIC_01967	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
EPEMNGIC_01968	5.34e-190	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
EPEMNGIC_01969	1.45e-153	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
EPEMNGIC_01971	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPEMNGIC_01972	2.76e-212	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
EPEMNGIC_01973	1.81e-291	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
EPEMNGIC_01974	1.02e-164	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
EPEMNGIC_01975	6.65e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
EPEMNGIC_01976	7.79e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
EPEMNGIC_01977	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
EPEMNGIC_01978	4.96e-223	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
EPEMNGIC_01979	2.95e-50	-	-	-	K	-	-	-	NAD+ binding
EPEMNGIC_01980	8.39e-217	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
EPEMNGIC_01981	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
EPEMNGIC_01982	1.46e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
EPEMNGIC_01983	1.66e-97	-	-	-	L	-	-	-	ATPase involved in DNA repair
EPEMNGIC_01985	2.7e-37	-	-	-	-	-	-	-	-
EPEMNGIC_01987	2.01e-35	-	-	-	-	-	-	-	-
EPEMNGIC_01988	1.18e-27	-	-	-	-	-	-	-	-
EPEMNGIC_01989	1.11e-21	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
EPEMNGIC_02002	5.5e-05	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
EPEMNGIC_02006	1.28e-33	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
EPEMNGIC_02009	6.49e-13	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
EPEMNGIC_02012	8.23e-32	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
EPEMNGIC_02013	9.59e-36	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
EPEMNGIC_02014	2.85e-33	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
EPEMNGIC_02015	1.99e-85	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
EPEMNGIC_02017	2.24e-49	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
EPEMNGIC_02018	1.18e-81	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
EPEMNGIC_02019	3.03e-104	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
EPEMNGIC_02020	2.19e-60	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
EPEMNGIC_02021	2.47e-139	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
EPEMNGIC_02022	3.22e-128	epsB	-	-	M	-	-	-	biosynthesis protein
EPEMNGIC_02023	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
EPEMNGIC_02024	0.0	-	-	-	L	-	-	-	Transposase
EPEMNGIC_02025	1.3e-262	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EPEMNGIC_02026	2.06e-278	-	-	-	G	-	-	-	Transporter, major facilitator family protein
EPEMNGIC_02027	3.16e-313	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
EPEMNGIC_02028	1.39e-33	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
EPEMNGIC_02029	4.99e-128	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
EPEMNGIC_02030	2e-70	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EPEMNGIC_02031	6.78e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
EPEMNGIC_02032	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
EPEMNGIC_02033	4.1e-67	entB	-	-	Q	-	-	-	Isochorismatase family
EPEMNGIC_02034	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
EPEMNGIC_02035	3.59e-240	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPEMNGIC_02036	9.26e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EPEMNGIC_02037	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPEMNGIC_02038	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
EPEMNGIC_02039	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPEMNGIC_02040	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
EPEMNGIC_02041	1.23e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
EPEMNGIC_02042	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
EPEMNGIC_02043	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPEMNGIC_02044	5.62e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPEMNGIC_02045	1.9e-145	-	-	-	S	-	-	-	(CBS) domain
EPEMNGIC_02046	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
EPEMNGIC_02047	5.33e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
EPEMNGIC_02048	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
EPEMNGIC_02049	2.17e-81	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
EPEMNGIC_02050	2.55e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPEMNGIC_02051	1.61e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPEMNGIC_02052	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
EPEMNGIC_02053	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPEMNGIC_02054	9.07e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
EPEMNGIC_02055	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EPEMNGIC_02056	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EPEMNGIC_02057	5.99e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
EPEMNGIC_02058	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
EPEMNGIC_02059	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EPEMNGIC_02060	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPEMNGIC_02061	4.32e-203	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
EPEMNGIC_02062	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
EPEMNGIC_02063	1.15e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPEMNGIC_02064	4.33e-154	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
EPEMNGIC_02065	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
EPEMNGIC_02066	2.37e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPEMNGIC_02067	9.19e-193	-	-	-	G	-	-	-	Right handed beta helix region
EPEMNGIC_02068	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
EPEMNGIC_02069	1.01e-160	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
EPEMNGIC_02070	2.26e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
EPEMNGIC_02071	2.26e-303	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EPEMNGIC_02072	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
EPEMNGIC_02073	1.58e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPEMNGIC_02074	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPEMNGIC_02075	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EPEMNGIC_02076	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
EPEMNGIC_02077	9.72e-188	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
EPEMNGIC_02078	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
EPEMNGIC_02079	4.65e-190	yidA	-	-	S	-	-	-	hydrolase
EPEMNGIC_02080	2.58e-102	-	-	-	-	-	-	-	-
EPEMNGIC_02081	9.36e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPEMNGIC_02082	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPEMNGIC_02083	5.24e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
EPEMNGIC_02084	3.54e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
EPEMNGIC_02085	9.8e-158	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
EPEMNGIC_02086	3.48e-216	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
EPEMNGIC_02087	6.98e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPEMNGIC_02088	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
EPEMNGIC_02089	6.45e-209	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPEMNGIC_02090	8.57e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EPEMNGIC_02091	3.73e-200	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
EPEMNGIC_02092	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPEMNGIC_02093	9.56e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
EPEMNGIC_02095	3.28e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
EPEMNGIC_02096	1.89e-228	-	-	-	-	-	-	-	-
EPEMNGIC_02097	5.82e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
EPEMNGIC_02098	2.53e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
EPEMNGIC_02099	9.18e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
EPEMNGIC_02100	5.96e-241	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
EPEMNGIC_02101	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
EPEMNGIC_02102	0.0	-	-	-	L	-	-	-	DNA helicase
EPEMNGIC_02103	4.11e-256	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
EPEMNGIC_02104	4.74e-248	eriC	-	-	P	ko:K03281	-	ko00000	chloride
EPEMNGIC_02105	3.87e-111	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
EPEMNGIC_02107	2.53e-71	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
EPEMNGIC_02108	4.95e-36	-	-	-	-	-	-	-	-
EPEMNGIC_02111	1.55e-09	-	-	-	K	-	-	-	Helix-turn-helix domain
EPEMNGIC_02112	1.78e-48	-	-	-	D	-	-	-	nuclear chromosome segregation
EPEMNGIC_02116	1.95e-98	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
EPEMNGIC_02117	7.85e-135	yocS	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
EPEMNGIC_02118	1.6e-163	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
EPEMNGIC_02119	2.76e-103	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EPEMNGIC_02120	1.02e-294	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EPEMNGIC_02121	1.45e-260	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPEMNGIC_02122	7.73e-260	-	-	-	G	-	-	-	Major Facilitator Superfamily
EPEMNGIC_02123	4.35e-198	menH	4.2.99.20	-	I	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
EPEMNGIC_02124	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EPEMNGIC_02125	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	chorismate binding enzyme
EPEMNGIC_02126	7.82e-67	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)