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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NEPIILCK_00003	7.38e-48	-	-	-	S	-	-	-	Bacteriophage holin family
NEPIILCK_00004	1.99e-75	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NEPIILCK_00005	1.81e-253	-	-	-	M	-	-	-	hydrolase, family 25
NEPIILCK_00006	0.0	-	-	-	O	-	-	-	Arylsulfotransferase (ASST)
NEPIILCK_00007	9.72e-156	csrR	-	-	K	-	-	-	response regulator
NEPIILCK_00008	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEPIILCK_00009	0.0	potE	-	-	E	-	-	-	Amino Acid
NEPIILCK_00010	1.28e-293	-	-	-	V	-	-	-	MatE
NEPIILCK_00011	5.52e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
NEPIILCK_00012	9.55e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEPIILCK_00013	2.86e-57	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NEPIILCK_00014	2.22e-185	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEPIILCK_00015	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NEPIILCK_00016	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NEPIILCK_00017	2.12e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NEPIILCK_00018	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEPIILCK_00019	1.98e-147	-	-	-	M	-	-	-	PFAM NLP P60 protein
NEPIILCK_00020	8.38e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NEPIILCK_00021	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEPIILCK_00022	5.43e-91	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NEPIILCK_00023	0.0	-	-	-	S	-	-	-	membrane
NEPIILCK_00024	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NEPIILCK_00025	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NEPIILCK_00026	1.55e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NEPIILCK_00027	5.62e-146	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
NEPIILCK_00028	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
NEPIILCK_00029	2.06e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NEPIILCK_00030	2.81e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
NEPIILCK_00031	9.76e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
NEPIILCK_00032	6.56e-223	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NEPIILCK_00033	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NEPIILCK_00034	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NEPIILCK_00035	5.1e-284	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NEPIILCK_00036	1.28e-18	-	-	-	-	-	-	-	-
NEPIILCK_00037	2.51e-199	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NEPIILCK_00038	0.0	-	-	-	M	-	-	-	Rib/alpha-like repeat
NEPIILCK_00039	1.32e-220	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NEPIILCK_00040	7.05e-273	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NEPIILCK_00041	4.41e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
NEPIILCK_00042	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEPIILCK_00043	6.91e-235	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
NEPIILCK_00044	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NEPIILCK_00045	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NEPIILCK_00046	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
NEPIILCK_00047	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
NEPIILCK_00048	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
NEPIILCK_00049	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NEPIILCK_00050	4.06e-93	-	-	-	-	-	-	-	-
NEPIILCK_00051	6.34e-128	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
NEPIILCK_00052	8.5e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NEPIILCK_00053	2.34e-154	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NEPIILCK_00054	1.85e-264	-	-	-	S	-	-	-	associated with various cellular activities
NEPIILCK_00055	3.55e-296	-	-	-	S	-	-	-	Putative metallopeptidase domain
NEPIILCK_00056	2.1e-64	-	-	-	-	-	-	-	-
NEPIILCK_00057	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
NEPIILCK_00058	1.01e-140	-	-	-	K	-	-	-	Helix-turn-helix domain
NEPIILCK_00059	5.77e-111	ymdB	-	-	S	-	-	-	Macro domain protein
NEPIILCK_00060	6.16e-247	-	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_00061	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEPIILCK_00062	1.38e-67	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NEPIILCK_00063	1.03e-210	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NEPIILCK_00064	1.45e-194	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
NEPIILCK_00065	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NEPIILCK_00066	5.84e-173	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00067	1.39e-229	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
NEPIILCK_00068	4.33e-161	XK27_10500	-	-	K	-	-	-	response regulator
NEPIILCK_00069	4.18e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
NEPIILCK_00070	1.38e-175	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NEPIILCK_00071	2.74e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NEPIILCK_00072	1.11e-261	-	-	-	-	-	-	-	-
NEPIILCK_00073	1.76e-68	-	-	-	-	-	-	-	-
NEPIILCK_00074	1.21e-48	-	-	-	-	-	-	-	-
NEPIILCK_00075	5.33e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
NEPIILCK_00076	7.76e-187	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
NEPIILCK_00077	1.05e-224	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
NEPIILCK_00078	1.03e-287	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NEPIILCK_00079	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NEPIILCK_00080	6.6e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NEPIILCK_00081	3.79e-135	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NEPIILCK_00082	1.24e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NEPIILCK_00083	1.39e-106	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
NEPIILCK_00084	1.76e-99	usp5	-	-	T	-	-	-	universal stress protein
NEPIILCK_00085	8.49e-66	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
NEPIILCK_00087	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NEPIILCK_00088	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
NEPIILCK_00089	1.91e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NEPIILCK_00090	9.24e-55	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
NEPIILCK_00091	2.41e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
NEPIILCK_00092	1.21e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NEPIILCK_00093	2.86e-07	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
NEPIILCK_00094	4.34e-200	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NEPIILCK_00095	2.44e-244	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NEPIILCK_00096	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NEPIILCK_00097	1.44e-277	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NEPIILCK_00098	4.76e-35	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NEPIILCK_00099	9.03e-148	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NEPIILCK_00100	5.22e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NEPIILCK_00101	2.29e-137	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
NEPIILCK_00102	2.49e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00103	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NEPIILCK_00104	8.79e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
NEPIILCK_00105	3.05e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_00106	4.88e-263	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NEPIILCK_00107	0.0	cadA	-	-	P	-	-	-	P-type ATPase
NEPIILCK_00108	7.59e-161	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NEPIILCK_00109	7.41e-163	-	-	-	-	-	-	-	-
NEPIILCK_00110	4.72e-72	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
NEPIILCK_00111	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
NEPIILCK_00113	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
NEPIILCK_00114	5.32e-109	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
NEPIILCK_00115	5.89e-231	ydhF	-	-	S	-	-	-	Aldo keto reductase
NEPIILCK_00117	1.15e-263	-	-	-	-	-	-	-	-
NEPIILCK_00118	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPIILCK_00119	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPIILCK_00120	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPIILCK_00121	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEPIILCK_00122	2.31e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NEPIILCK_00123	2.56e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NEPIILCK_00124	1.97e-230	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
NEPIILCK_00125	7.59e-14	-	-	-	-	-	-	-	-
NEPIILCK_00131	1.11e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NEPIILCK_00132	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
NEPIILCK_00133	1.22e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NEPIILCK_00134	6.58e-152	-	-	-	I	-	-	-	phosphatase
NEPIILCK_00135	3.54e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
NEPIILCK_00136	1.04e-166	-	-	-	S	-	-	-	Putative threonine/serine exporter
NEPIILCK_00137	8.84e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NEPIILCK_00138	2.22e-159	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
NEPIILCK_00139	2e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
NEPIILCK_00140	6.28e-153	-	-	-	S	-	-	-	membrane
NEPIILCK_00141	2.34e-142	-	-	-	S	-	-	-	VIT family
NEPIILCK_00142	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NEPIILCK_00143	8.01e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00144	1.1e-194	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEPIILCK_00145	7.44e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NEPIILCK_00146	1.04e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NEPIILCK_00147	3.69e-278	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NEPIILCK_00148	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEPIILCK_00149	2e-75	-	-	-	-	-	-	-	-
NEPIILCK_00150	3.21e-99	-	-	-	K	-	-	-	MerR HTH family regulatory protein
NEPIILCK_00151	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NEPIILCK_00152	3.46e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
NEPIILCK_00153	1.86e-209	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NEPIILCK_00155	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEPIILCK_00156	2.28e-133	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NEPIILCK_00157	4.87e-235	-	-	-	I	-	-	-	Alpha beta
NEPIILCK_00158	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_00159	1.91e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
NEPIILCK_00160	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
NEPIILCK_00161	4.66e-201	-	-	-	K	-	-	-	LysR family
NEPIILCK_00162	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
NEPIILCK_00163	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
NEPIILCK_00164	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NEPIILCK_00165	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
NEPIILCK_00166	3.16e-206	mleR	-	-	K	-	-	-	LysR family
NEPIILCK_00167	4.07e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NEPIILCK_00168	1.57e-262	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
NEPIILCK_00169	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
NEPIILCK_00170	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
NEPIILCK_00171	8.23e-39	-	-	-	-	-	-	-	-
NEPIILCK_00172	7.41e-255	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
NEPIILCK_00173	6.26e-96	-	-	-	-	-	-	-	-
NEPIILCK_00174	2e-283	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NEPIILCK_00176	1.9e-99	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
NEPIILCK_00181	2.64e-156	-	-	-	F	-	-	-	deoxynucleoside kinase
NEPIILCK_00182	4.93e-208	-	-	-	-	-	-	-	-
NEPIILCK_00190	1.11e-95	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
NEPIILCK_00191	1.49e-41	-	-	-	-	-	-	-	-
NEPIILCK_00192	1.48e-48	-	-	-	-	-	-	-	-
NEPIILCK_00195	1.03e-46	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NEPIILCK_00196	9.11e-170	-	-	-	S	-	-	-	Putative HNHc nuclease
NEPIILCK_00197	3.96e-71	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEPIILCK_00205	5.34e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
NEPIILCK_00206	2.11e-28	-	-	-	-	-	-	-	-
NEPIILCK_00207	7.91e-63	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NEPIILCK_00208	1.66e-99	-	-	-	E	-	-	-	IrrE N-terminal-like domain
NEPIILCK_00212	4.74e-86	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEPIILCK_00213	3.66e-165	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NEPIILCK_00214	2.24e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NEPIILCK_00215	3.51e-180	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NEPIILCK_00216	2.49e-84	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NEPIILCK_00217	1.36e-210	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
NEPIILCK_00218	5.36e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
NEPIILCK_00219	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NEPIILCK_00220	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NEPIILCK_00221	7.81e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
NEPIILCK_00222	3.11e-18	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
NEPIILCK_00223	6.62e-172	-	-	-	M	-	-	-	PFAM NLP P60 protein
NEPIILCK_00224	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NEPIILCK_00225	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NEPIILCK_00226	9.34e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00227	3.1e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
NEPIILCK_00228	2.79e-75	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NEPIILCK_00229	1.3e-73	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NEPIILCK_00230	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
NEPIILCK_00231	1.13e-218	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NEPIILCK_00232	1.93e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NEPIILCK_00233	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NEPIILCK_00234	1.67e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
NEPIILCK_00235	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NEPIILCK_00236	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NEPIILCK_00237	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
NEPIILCK_00238	1.77e-56	-	-	-	-	-	-	-	-
NEPIILCK_00239	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEPIILCK_00240	3.36e-44	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NEPIILCK_00241	1.55e-135	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NEPIILCK_00242	5.56e-196	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NEPIILCK_00243	3.18e-45	-	-	-	-	-	-	-	-
NEPIILCK_00244	1.42e-203	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NEPIILCK_00245	1.58e-16	-	-	-	G	-	-	-	Major Facilitator
NEPIILCK_00246	1.57e-67	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NEPIILCK_00247	1.45e-161	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NEPIILCK_00248	8.39e-165	-	-	-	G	-	-	-	Major Facilitator Superfamily
NEPIILCK_00249	2.93e-08	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
NEPIILCK_00250	3.87e-184	-	-	-	-	-	-	-	-
NEPIILCK_00251	5.83e-309	-	-	-	M	-	-	-	Glycosyl transferase
NEPIILCK_00252	1.11e-285	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
NEPIILCK_00253	2.31e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
NEPIILCK_00254	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
NEPIILCK_00255	1.37e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
NEPIILCK_00256	3.26e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
NEPIILCK_00257	1.08e-113	-	-	-	Q	-	-	-	Methyltransferase
NEPIILCK_00258	7.69e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NEPIILCK_00259	2.69e-228	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NEPIILCK_00260	9.11e-208	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NEPIILCK_00261	2.65e-108	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NEPIILCK_00262	2.71e-219	-	-	-	S	-	-	-	Conserved hypothetical protein 698
NEPIILCK_00263	1.31e-210	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
NEPIILCK_00264	4.42e-141	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NEPIILCK_00265	4.63e-159	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
NEPIILCK_00266	1.04e-218	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
NEPIILCK_00267	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NEPIILCK_00268	0.0	arcT	-	-	E	-	-	-	Dipeptidase
NEPIILCK_00269	3.99e-72	-	-	-	Q	-	-	-	Methyltransferase
NEPIILCK_00270	6.29e-193	nikA	-	-	E	ko:K15584	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Nickel ABC transporter
NEPIILCK_00271	1.12e-55	-	-	-	P	ko:K02033,ko:K15585	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
NEPIILCK_00272	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEPIILCK_00273	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
NEPIILCK_00274	1.91e-178	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NEPIILCK_00275	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NEPIILCK_00276	5.75e-122	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
NEPIILCK_00277	2.42e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
NEPIILCK_00278	1.4e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
NEPIILCK_00279	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
NEPIILCK_00280	5.13e-61	-	-	-	-	-	-	-	-
NEPIILCK_00281	7.66e-309	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
NEPIILCK_00282	2.47e-112	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NEPIILCK_00283	4.85e-29	-	-	-	-	-	-	-	-
NEPIILCK_00284	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
NEPIILCK_00285	2.41e-179	-	-	-	S	-	-	-	Membrane
NEPIILCK_00286	2.59e-175	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
NEPIILCK_00287	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NEPIILCK_00288	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NEPIILCK_00289	2.15e-298	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NEPIILCK_00290	1.04e-307	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
NEPIILCK_00291	3.78e-263	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
NEPIILCK_00292	0.0	tdc	4.1.1.25	-	E	ko:K22330	ko00350,map00350	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
NEPIILCK_00293	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NEPIILCK_00294	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NEPIILCK_00295	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEPIILCK_00296	6.86e-61	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NEPIILCK_00297	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NEPIILCK_00298	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NEPIILCK_00299	5.48e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NEPIILCK_00300	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
NEPIILCK_00301	3.7e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NEPIILCK_00302	1.07e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NEPIILCK_00303	3.17e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NEPIILCK_00304	2.58e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
NEPIILCK_00305	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NEPIILCK_00306	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NEPIILCK_00307	6.8e-224	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NEPIILCK_00308	7.32e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NEPIILCK_00309	7.34e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
NEPIILCK_00310	4.12e-133	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
NEPIILCK_00311	5.83e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NEPIILCK_00312	1.26e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEPIILCK_00313	2.35e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NEPIILCK_00314	3.64e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NEPIILCK_00315	3.01e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
NEPIILCK_00316	4.39e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NEPIILCK_00317	2.41e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEPIILCK_00318	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
NEPIILCK_00319	6.56e-121	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
NEPIILCK_00320	6.64e-206	-	-	-	EG	-	-	-	EamA-like transporter family
NEPIILCK_00321	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
NEPIILCK_00322	1.21e-153	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NEPIILCK_00323	7.62e-132	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NEPIILCK_00324	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NEPIILCK_00325	1.01e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NEPIILCK_00326	4.87e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NEPIILCK_00327	5.39e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
NEPIILCK_00328	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
NEPIILCK_00329	8.16e-93	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NEPIILCK_00330	1.68e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NEPIILCK_00331	1.07e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
NEPIILCK_00332	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
NEPIILCK_00333	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
NEPIILCK_00334	2.95e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
NEPIILCK_00335	7.18e-126	-	-	-	-	-	-	-	-
NEPIILCK_00336	1.24e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NEPIILCK_00337	5.95e-202	gspA	-	-	M	-	-	-	family 8
NEPIILCK_00338	5.74e-204	-	-	-	S	-	-	-	Alpha beta hydrolase
NEPIILCK_00339	4.52e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NEPIILCK_00340	1.75e-189	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NEPIILCK_00341	5.27e-102	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
NEPIILCK_00342	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
NEPIILCK_00343	3.32e-194	yvgN	-	-	C	-	-	-	Aldo keto reductase
NEPIILCK_00344	5.68e-83	-	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_00345	9.73e-100	-	-	-	S	-	-	-	Cupin domain
NEPIILCK_00346	2.61e-95	-	-	-	S	-	-	-	UPF0756 membrane protein
NEPIILCK_00347	5.01e-310	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
NEPIILCK_00348	2.39e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
NEPIILCK_00349	2.75e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
NEPIILCK_00350	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
NEPIILCK_00351	6.69e-175	-	-	-	S	-	-	-	DUF218 domain
NEPIILCK_00352	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NEPIILCK_00353	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
NEPIILCK_00354	4.81e-157	-	-	-	S	-	-	-	SNARE associated Golgi protein
NEPIILCK_00355	1.09e-292	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
NEPIILCK_00356	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NEPIILCK_00358	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NEPIILCK_00359	6.94e-202	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
NEPIILCK_00360	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEPIILCK_00361	4.12e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
NEPIILCK_00362	6.49e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
NEPIILCK_00363	2.41e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
NEPIILCK_00364	1.24e-115	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NEPIILCK_00365	1.23e-50	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NEPIILCK_00366	1.75e-29	-	-	-	-	-	-	-	-
NEPIILCK_00367	3.96e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
NEPIILCK_00368	5.24e-191	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NEPIILCK_00369	2.17e-61	yrvD	-	-	S	-	-	-	Pfam:DUF1049
NEPIILCK_00370	6.29e-100	-	-	-	-	-	-	-	-
NEPIILCK_00371	1.62e-229	-	-	-	-	-	-	-	-
NEPIILCK_00372	4.32e-235	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NEPIILCK_00373	5.63e-179	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NEPIILCK_00374	2.64e-167	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NEPIILCK_00375	2.64e-103	-	-	-	S	-	-	-	Flavodoxin
NEPIILCK_00376	2.29e-84	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
NEPIILCK_00377	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
NEPIILCK_00378	3.17e-280	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
NEPIILCK_00379	1.93e-212	-	-	-	H	-	-	-	geranyltranstransferase activity
NEPIILCK_00380	6.39e-233	-	-	-	-	-	-	-	-
NEPIILCK_00381	3.11e-26	-	-	-	-	-	-	-	-
NEPIILCK_00382	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
NEPIILCK_00383	1.77e-240	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
NEPIILCK_00384	6.37e-60	-	-	-	-	-	-	-	-
NEPIILCK_00385	4.78e-135	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NEPIILCK_00386	2.28e-108	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
NEPIILCK_00387	8.56e-289	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
NEPIILCK_00388	1.85e-104	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
NEPIILCK_00389	8.49e-242	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
NEPIILCK_00390	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NEPIILCK_00391	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NEPIILCK_00392	1.21e-129	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
NEPIILCK_00393	4.68e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
NEPIILCK_00394	3.26e-169	-	-	-	EG	-	-	-	EamA-like transporter family
NEPIILCK_00395	4.94e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NEPIILCK_00396	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NEPIILCK_00397	2.03e-81	-	-	-	-	-	-	-	-
NEPIILCK_00398	1.35e-127	-	-	-	-	-	-	-	-
NEPIILCK_00400	1.17e-19	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEPIILCK_00401	3.3e-31	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEPIILCK_00402	1.57e-124	-	-	-	K	-	-	-	acetyltransferase
NEPIILCK_00403	1.24e-215	-	-	-	-	-	-	-	-
NEPIILCK_00405	1.06e-276	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NEPIILCK_00406	9.52e-124	-	-	-	S	-	-	-	AmiS/UreI family transporter
NEPIILCK_00407	3.44e-60	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
NEPIILCK_00408	2.83e-84	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
NEPIILCK_00409	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
NEPIILCK_00410	2.54e-101	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NEPIILCK_00411	2.3e-167	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NEPIILCK_00412	3.44e-146	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NEPIILCK_00413	2.25e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NEPIILCK_00414	1.65e-55	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEPIILCK_00415	3.46e-95	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NEPIILCK_00416	4.32e-234	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
NEPIILCK_00417	6.72e-183	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NEPIILCK_00418	6.63e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEPIILCK_00419	2.06e-170	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
NEPIILCK_00420	1.91e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NEPIILCK_00421	1.86e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NEPIILCK_00422	3.01e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
NEPIILCK_00423	1.28e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NEPIILCK_00424	2.89e-160	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NEPIILCK_00428	2.11e-30	-	-	-	E	-	-	-	Pfam:DUF955
NEPIILCK_00429	5.69e-16	-	-	-	S	-	-	-	Protein conserved in bacteria
NEPIILCK_00430	5.44e-31	-	-	-	-	-	-	-	-
NEPIILCK_00431	6.91e-25	-	-	-	-	-	-	-	-
NEPIILCK_00432	3.22e-39	-	-	-	S	-	-	-	Domain of unknown function (DUF4417)
NEPIILCK_00433	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NEPIILCK_00434	2.6e-234	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
NEPIILCK_00435	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEPIILCK_00436	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NEPIILCK_00437	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NEPIILCK_00438	6.4e-260	camS	-	-	S	-	-	-	sex pheromone
NEPIILCK_00439	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NEPIILCK_00440	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NEPIILCK_00441	2.19e-270	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NEPIILCK_00442	3.91e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NEPIILCK_00443	3.07e-149	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
NEPIILCK_00444	1.56e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
NEPIILCK_00447	2.18e-105	-	-	-	S	-	-	-	GIY-YIG catalytic domain
NEPIILCK_00448	1.83e-112	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
NEPIILCK_00449	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NEPIILCK_00450	1.16e-216	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
NEPIILCK_00451	4.7e-215	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
NEPIILCK_00452	6.81e-273	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
NEPIILCK_00453	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NEPIILCK_00454	3.95e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
NEPIILCK_00455	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
NEPIILCK_00456	1.06e-235	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
NEPIILCK_00457	6.28e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
NEPIILCK_00458	2.29e-227	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NEPIILCK_00459	3.6e-160	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
NEPIILCK_00460	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
NEPIILCK_00461	1.18e-168	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
NEPIILCK_00462	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
NEPIILCK_00463	1.8e-190	-	-	-	O	-	-	-	Band 7 protein
NEPIILCK_00464	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
NEPIILCK_00465	1.77e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
NEPIILCK_00466	1.18e-50	-	-	-	S	-	-	-	Cytochrome B5
NEPIILCK_00467	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NEPIILCK_00468	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NEPIILCK_00469	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NEPIILCK_00470	1.32e-192	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NEPIILCK_00471	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NEPIILCK_00472	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NEPIILCK_00473	6.57e-136	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
NEPIILCK_00474	3.14e-254	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NEPIILCK_00475	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NEPIILCK_00476	2.37e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
NEPIILCK_00477	5.25e-59	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
NEPIILCK_00478	7.88e-286	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NEPIILCK_00479	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NEPIILCK_00480	9.67e-175	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
NEPIILCK_00481	1.66e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NEPIILCK_00482	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
NEPIILCK_00483	2.13e-311	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NEPIILCK_00484	3.28e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
NEPIILCK_00485	4.05e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
NEPIILCK_00486	6.83e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NEPIILCK_00487	2.79e-107	-	-	-	-	-	-	-	-
NEPIILCK_00488	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NEPIILCK_00489	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
NEPIILCK_00490	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NEPIILCK_00491	1.52e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEPIILCK_00492	3.92e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
NEPIILCK_00493	3.7e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NEPIILCK_00494	2.92e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
NEPIILCK_00495	6.2e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NEPIILCK_00496	6.95e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
NEPIILCK_00497	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
NEPIILCK_00498	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NEPIILCK_00499	5.34e-134	-	-	-	-	-	-	-	-
NEPIILCK_00500	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NEPIILCK_00501	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NEPIILCK_00502	4.68e-187	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
NEPIILCK_00503	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NEPIILCK_00504	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NEPIILCK_00505	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
NEPIILCK_00506	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NEPIILCK_00507	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEPIILCK_00508	7.62e-290	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NEPIILCK_00509	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NEPIILCK_00511	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NEPIILCK_00512	1.67e-307	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
NEPIILCK_00513	1.83e-21	-	-	-	-	-	-	-	-
NEPIILCK_00515	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NEPIILCK_00516	1.41e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NEPIILCK_00517	3.42e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NEPIILCK_00518	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
NEPIILCK_00519	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NEPIILCK_00520	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NEPIILCK_00521	1.03e-19	-	-	-	-	-	-	-	-
NEPIILCK_00522	1.02e-149	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
NEPIILCK_00523	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NEPIILCK_00524	9.54e-113	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
NEPIILCK_00525	2.43e-207	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
NEPIILCK_00526	1.31e-268	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
NEPIILCK_00527	3.37e-222	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NEPIILCK_00528	3.09e-212	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
NEPIILCK_00529	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
NEPIILCK_00530	4.83e-173	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
NEPIILCK_00531	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NEPIILCK_00532	4.67e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NEPIILCK_00533	2.72e-199	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NEPIILCK_00534	2.29e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NEPIILCK_00535	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
NEPIILCK_00536	1.49e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NEPIILCK_00537	2.73e-239	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NEPIILCK_00538	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEPIILCK_00539	5e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NEPIILCK_00540	1.98e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
NEPIILCK_00541	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
NEPIILCK_00542	1.05e-183	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
NEPIILCK_00543	1.63e-145	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
NEPIILCK_00544	3.26e-57	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPIILCK_00545	1.01e-79	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPIILCK_00546	7.45e-07	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
NEPIILCK_00547	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
NEPIILCK_00548	3.67e-232	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
NEPIILCK_00549	3.17e-298	isp	-	-	L	-	-	-	Transposase
NEPIILCK_00550	3.08e-162	-	3.2.1.23, 3.2.1.89	-	G	ko:K01190,ko:K01224	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	arabinogalactan endo-1,4-beta-galactosidase activity
NEPIILCK_00551	1.63e-82	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
NEPIILCK_00552	2.92e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00553	9.18e-145	-	-	-	-	-	-	-	-
NEPIILCK_00554	3.86e-182	-	-	-	G	-	-	-	MucBP domain
NEPIILCK_00555	4.48e-130	-	-	-	S	-	-	-	Pfam:DUF3816
NEPIILCK_00556	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NEPIILCK_00557	9.69e-38	-	-	-	-	-	-	-	-
NEPIILCK_00558	5.05e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
NEPIILCK_00559	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEPIILCK_00560	2.1e-289	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NEPIILCK_00561	7.98e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
NEPIILCK_00562	3.8e-228	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NEPIILCK_00563	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NEPIILCK_00565	3.53e-275	xylR	-	-	GK	-	-	-	ROK family
NEPIILCK_00566	2.05e-38	-	-	-	-	-	-	-	-
NEPIILCK_00567	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NEPIILCK_00568	1.41e-152	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
NEPIILCK_00569	1.91e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NEPIILCK_00570	0.0	yclK	-	-	T	-	-	-	Histidine kinase
NEPIILCK_00571	4.48e-171	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
NEPIILCK_00573	1.27e-109	lytE	-	-	M	-	-	-	Lysin motif
NEPIILCK_00574	4.13e-186	-	-	-	S	-	-	-	Cof-like hydrolase
NEPIILCK_00575	3.7e-106	-	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_00576	0.0	oatA	-	-	I	-	-	-	Acyltransferase
NEPIILCK_00577	5.17e-70	-	-	-	-	-	-	-	-
NEPIILCK_00578	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NEPIILCK_00579	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NEPIILCK_00580	8.71e-164	ybbR	-	-	S	-	-	-	YbbR-like protein
NEPIILCK_00581	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NEPIILCK_00582	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NEPIILCK_00583	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NEPIILCK_00584	2.49e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NEPIILCK_00585	9.65e-180	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEPIILCK_00586	3.3e-200	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEPIILCK_00587	1.23e-186	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NEPIILCK_00588	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NEPIILCK_00589	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NEPIILCK_00590	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NEPIILCK_00591	5.37e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NEPIILCK_00592	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NEPIILCK_00593	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NEPIILCK_00594	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NEPIILCK_00595	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NEPIILCK_00596	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NEPIILCK_00597	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NEPIILCK_00598	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NEPIILCK_00599	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NEPIILCK_00600	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NEPIILCK_00601	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NEPIILCK_00602	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NEPIILCK_00603	3.02e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NEPIILCK_00604	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NEPIILCK_00605	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NEPIILCK_00606	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NEPIILCK_00607	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NEPIILCK_00608	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NEPIILCK_00609	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NEPIILCK_00610	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NEPIILCK_00611	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NEPIILCK_00612	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NEPIILCK_00613	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NEPIILCK_00614	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NEPIILCK_00615	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NEPIILCK_00616	4.86e-185	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
NEPIILCK_00617	0.0	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
NEPIILCK_00618	0.0	-	-	-	G	-	-	-	Right handed beta helix region
NEPIILCK_00619	7.22e-28	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
NEPIILCK_00620	8.8e-17	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	polysaccharide deacetylase
NEPIILCK_00621	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
NEPIILCK_00622	0.0	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
NEPIILCK_00623	2.61e-199	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
NEPIILCK_00624	3.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NEPIILCK_00625	4.6e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
NEPIILCK_00626	5.49e-207	-	-	-	EG	-	-	-	EamA-like transporter family
NEPIILCK_00627	1.72e-134	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
NEPIILCK_00628	3.35e-75	-	-	-	S	-	-	-	Cupredoxin-like domain
NEPIILCK_00629	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
NEPIILCK_00630	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NEPIILCK_00631	5.43e-114	-	-	-	-	-	-	-	-
NEPIILCK_00633	1.28e-75	-	-	-	-	-	-	-	-
NEPIILCK_00634	1.62e-193	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NEPIILCK_00635	2.3e-46	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NEPIILCK_00636	1.87e-74	-	-	-	S	-	-	-	Pfam:DUF59
NEPIILCK_00637	8.25e-250	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NEPIILCK_00638	2.21e-190	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
NEPIILCK_00639	1.19e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NEPIILCK_00640	1.78e-209	-	-	-	-	-	-	-	-
NEPIILCK_00641	6.42e-201	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
NEPIILCK_00642	1.61e-237	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
NEPIILCK_00643	6.1e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
NEPIILCK_00644	1.93e-101	yybA	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_00645	5.25e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
NEPIILCK_00646	4e-117	-	-	-	GM	-	-	-	epimerase
NEPIILCK_00647	1.63e-197	-	-	-	V	-	-	-	(ABC) transporter
NEPIILCK_00648	4.1e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
NEPIILCK_00649	4e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
NEPIILCK_00650	3.68e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
NEPIILCK_00651	3.59e-244	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
NEPIILCK_00652	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NEPIILCK_00653	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NEPIILCK_00654	1.8e-45	-	-	-	-	-	-	-	-
NEPIILCK_00655	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NEPIILCK_00656	5.21e-103	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NEPIILCK_00657	1.68e-189	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NEPIILCK_00658	4.3e-256	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
NEPIILCK_00659	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NEPIILCK_00660	2.76e-76	-	-	-	-	-	-	-	-
NEPIILCK_00661	1.19e-231	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
NEPIILCK_00662	1.08e-161	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NEPIILCK_00663	5.61e-71	-	-	-	-	-	-	-	-
NEPIILCK_00664	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NEPIILCK_00665	1.54e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NEPIILCK_00666	1.04e-211	-	-	-	G	-	-	-	Phosphotransferase enzyme family
NEPIILCK_00667	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NEPIILCK_00668	1.05e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00669	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NEPIILCK_00670	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NEPIILCK_00671	1.11e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
NEPIILCK_00672	3.39e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
NEPIILCK_00673	9.17e-71	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
NEPIILCK_00674	1.06e-88	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEPIILCK_00675	1.52e-233	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
NEPIILCK_00676	1.73e-56	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NEPIILCK_00678	1.96e-125	-	-	-	S	-	-	-	NgoFVII restriction endonuclease
NEPIILCK_00679	2.07e-197	nlaXM	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	cytosine-specific methyltransferase
NEPIILCK_00680	1.8e-63	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	DNA mismatch endonuclease Vsr
NEPIILCK_00685	1.54e-104	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NEPIILCK_00686	1.17e-48	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
NEPIILCK_00687	5.67e-129	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
NEPIILCK_00689	1.99e-66	-	-	-	L	-	-	-	Lactococcus lactis RepB C-terminus
NEPIILCK_00690	7.13e-119	-	-	-	L	-	-	-	Integrase
NEPIILCK_00692	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NEPIILCK_00693	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NEPIILCK_00694	2.66e-111	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NEPIILCK_00695	2.6e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NEPIILCK_00696	1.88e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NEPIILCK_00697	4.65e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NEPIILCK_00698	9.79e-278	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NEPIILCK_00699	4.28e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NEPIILCK_00700	1.03e-262	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NEPIILCK_00701	3.71e-76	-	-	-	-	-	-	-	-
NEPIILCK_00703	2.51e-239	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NEPIILCK_00704	4.37e-39	-	-	-	-	-	-	-	-
NEPIILCK_00705	3.55e-231	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
NEPIILCK_00706	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NEPIILCK_00707	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NEPIILCK_00708	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NEPIILCK_00709	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NEPIILCK_00710	1.06e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NEPIILCK_00711	3.11e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NEPIILCK_00712	7.06e-79	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NEPIILCK_00713	7.1e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NEPIILCK_00714	7.15e-232	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
NEPIILCK_00715	1.64e-215	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NEPIILCK_00716	2.87e-95	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NEPIILCK_00717	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NEPIILCK_00718	1.46e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NEPIILCK_00719	7.37e-273	-	-	-	G	-	-	-	Transporter, major facilitator family protein
NEPIILCK_00720	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NEPIILCK_00721	4.46e-147	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
NEPIILCK_00722	6.83e-226	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
NEPIILCK_00724	0.0	-	-	-	L	-	-	-	PLD-like domain
NEPIILCK_00725	1.85e-22	-	-	-	-	-	-	-	-
NEPIILCK_00726	1.14e-121	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
NEPIILCK_00727	4.75e-215	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
NEPIILCK_00728	1.41e-120	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain protein
NEPIILCK_00730	4.09e-294	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
NEPIILCK_00731	2.27e-65	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
NEPIILCK_00732	2.66e-62	-	-	-	-	-	-	-	-
NEPIILCK_00734	1.53e-269	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
NEPIILCK_00735	1.98e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NEPIILCK_00736	2.03e-200	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NEPIILCK_00737	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NEPIILCK_00738	1.44e-187	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NEPIILCK_00739	3.57e-191	-	-	-	E	-	-	-	Glyoxalase-like domain
NEPIILCK_00740	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
NEPIILCK_00741	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
NEPIILCK_00742	1.1e-125	-	-	-	S	-	-	-	reductase
NEPIILCK_00743	2.9e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NEPIILCK_00744	1.84e-22	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
NEPIILCK_00745	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
NEPIILCK_00746	2.46e-289	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
NEPIILCK_00747	1.46e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
NEPIILCK_00748	7.14e-193	yycI	-	-	S	-	-	-	YycH protein
NEPIILCK_00749	8.68e-316	yycH	-	-	S	-	-	-	YycH protein
NEPIILCK_00750	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NEPIILCK_00751	2.6e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NEPIILCK_00753	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NEPIILCK_00754	1.81e-94	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
NEPIILCK_00756	7.37e-156	-	-	-	S	-	-	-	Fic/DOC family
NEPIILCK_00757	3.08e-209	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
NEPIILCK_00758	1.57e-71	-	-	-	-	-	-	-	-
NEPIILCK_00759	8.85e-268	yttB	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_00760	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NEPIILCK_00761	5.1e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
NEPIILCK_00762	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NEPIILCK_00763	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NEPIILCK_00764	5.93e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NEPIILCK_00765	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NEPIILCK_00766	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEPIILCK_00767	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NEPIILCK_00768	1.7e-261	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NEPIILCK_00769	4.46e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
NEPIILCK_00770	1.15e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NEPIILCK_00771	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NEPIILCK_00772	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NEPIILCK_00773	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NEPIILCK_00774	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NEPIILCK_00775	1.47e-168	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
NEPIILCK_00776	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NEPIILCK_00777	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NEPIILCK_00778	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NEPIILCK_00779	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NEPIILCK_00780	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
NEPIILCK_00781	1.05e-150	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NEPIILCK_00782	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
NEPIILCK_00785	0.0	snf	-	-	KL	-	-	-	domain protein
NEPIILCK_00786	9.06e-185	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
NEPIILCK_00787	9.09e-25	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NEPIILCK_00788	2.25e-265	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NEPIILCK_00789	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
NEPIILCK_00790	2.86e-72	-	-	-	-	-	-	-	-
NEPIILCK_00791	4.21e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEPIILCK_00793	1.91e-297	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
NEPIILCK_00794	4.39e-244	mocA	-	-	S	-	-	-	Oxidoreductase
NEPIILCK_00795	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
NEPIILCK_00796	6.95e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NEPIILCK_00797	3.74e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
NEPIILCK_00798	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NEPIILCK_00799	1.64e-242	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
NEPIILCK_00800	2.61e-95	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
NEPIILCK_00801	5.33e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NEPIILCK_00802	1.7e-26	-	-	-	-	-	-	-	-
NEPIILCK_00803	4.43e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
NEPIILCK_00804	3.09e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NEPIILCK_00805	4.46e-187	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
NEPIILCK_00806	2.91e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
NEPIILCK_00807	2.14e-71	-	-	-	-	-	-	-	-
NEPIILCK_00808	1.85e-109	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NEPIILCK_00817	5.62e-75	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NEPIILCK_00818	1.15e-24	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NEPIILCK_00819	3.26e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
NEPIILCK_00820	2.41e-183	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NEPIILCK_00821	6.01e-263	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NEPIILCK_00822	8.18e-49	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
NEPIILCK_00823	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEPIILCK_00824	2.33e-91	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NEPIILCK_00825	2.62e-281	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NEPIILCK_00826	4.98e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NEPIILCK_00827	2.24e-193	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
NEPIILCK_00828	5.94e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEPIILCK_00829	9.67e-107	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEPIILCK_00830	1.09e-103	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NEPIILCK_00831	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
NEPIILCK_00832	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NEPIILCK_00834	1.98e-257	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEPIILCK_00835	1.36e-126	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NEPIILCK_00836	4.43e-254	-	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_00837	4.49e-162	-	-	-	M	-	-	-	Lysin motif
NEPIILCK_00838	5.69e-105	-	-	-	-	-	-	-	-
NEPIILCK_00839	9.66e-79	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NEPIILCK_00840	1.44e-99	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
NEPIILCK_00841	1.25e-124	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
NEPIILCK_00842	2.96e-265	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NEPIILCK_00843	3.7e-19	-	-	-	-	-	-	-	-
NEPIILCK_00844	1.25e-109	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
NEPIILCK_00845	9.33e-252	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NEPIILCK_00846	2.53e-146	-	-	-	S	-	-	-	Membrane
NEPIILCK_00847	5.86e-157	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
NEPIILCK_00848	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NEPIILCK_00850	6.52e-149	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
NEPIILCK_00851	3.32e-72	-	-	-	-	-	-	-	-
NEPIILCK_00853	1.94e-177	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NEPIILCK_00854	2.04e-65	-	-	-	-	-	-	-	-
NEPIILCK_00855	3.14e-254	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
NEPIILCK_00856	6.33e-294	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
NEPIILCK_00857	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NEPIILCK_00858	5.99e-137	-	-	-	NU	-	-	-	mannosyl-glycoprotein
NEPIILCK_00859	8.38e-186	-	-	-	S	-	-	-	Putative ABC-transporter type IV
NEPIILCK_00860	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
NEPIILCK_00863	5.58e-59	-	-	-	L	-	-	-	Type III restriction/modification enzyme methylation subunit
NEPIILCK_00864	1.25e-123	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
NEPIILCK_00865	0.0	sthIR	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
NEPIILCK_00866	1.51e-281	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
NEPIILCK_00867	1.11e-201	-	-	-	J	-	-	-	Methyltransferase
NEPIILCK_00868	2.33e-49	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
NEPIILCK_00870	3.65e-54	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
NEPIILCK_00871	1.09e-128	-	-	-	K	-	-	-	Cyclic nucleotide-binding domain
NEPIILCK_00872	6.78e-164	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
NEPIILCK_00873	4.16e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NEPIILCK_00874	1.18e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NEPIILCK_00875	1.83e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NEPIILCK_00876	5.74e-155	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
NEPIILCK_00877	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
NEPIILCK_00878	1.1e-194	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NEPIILCK_00879	9.76e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
NEPIILCK_00880	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
NEPIILCK_00881	1.02e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00882	8.15e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
NEPIILCK_00883	4.11e-292	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
NEPIILCK_00884	1.06e-314	ymfH	-	-	S	-	-	-	Peptidase M16
NEPIILCK_00885	2.78e-194	-	-	-	S	-	-	-	Helix-turn-helix domain
NEPIILCK_00886	2.91e-65	-	-	-	-	-	-	-	-
NEPIILCK_00888	4.01e-63	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NEPIILCK_00889	9.71e-76	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
NEPIILCK_00890	1.39e-129	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
NEPIILCK_00891	3.67e-176	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
NEPIILCK_00892	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
NEPIILCK_00893	3.81e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEPIILCK_00894	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NEPIILCK_00895	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
NEPIILCK_00896	1.82e-137	-	-	-	M	-	-	-	biosynthesis protein
NEPIILCK_00897	6.35e-276	cps3F	-	-	-	-	-	-	-
NEPIILCK_00898	2.22e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
NEPIILCK_00899	7.46e-149	-	-	-	M	-	-	-	Bacterial sugar transferase
NEPIILCK_00900	1e-218	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
NEPIILCK_00901	1.91e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
NEPIILCK_00902	3.12e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
NEPIILCK_00903	7.27e-42	-	-	-	-	-	-	-	-
NEPIILCK_00904	5.13e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
NEPIILCK_00905	1.83e-203	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NEPIILCK_00906	0.0	potE	-	-	E	-	-	-	Amino Acid
NEPIILCK_00907	9.46e-49	-	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_00908	6.25e-196	-	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_00909	9.12e-67	-	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_00910	1.78e-51	-	-	-	-	-	-	-	-
NEPIILCK_00911	0.0	ydaO	-	-	E	-	-	-	amino acid
NEPIILCK_00912	0.0	-	-	-	E	-	-	-	amino acid
NEPIILCK_00913	7.42e-44	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NEPIILCK_00914	4.31e-43	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	YbaK proline--tRNA ligase associated domain protein
NEPIILCK_00915	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NEPIILCK_00916	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NEPIILCK_00918	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NEPIILCK_00921	4e-55	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NEPIILCK_00922	3.03e-158	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NEPIILCK_00923	1.42e-304	-	-	-	T	-	-	-	GHKL domain
NEPIILCK_00924	5.37e-138	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NEPIILCK_00925	3.15e-141	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
NEPIILCK_00926	1.94e-13	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
NEPIILCK_00927	3.88e-71	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
NEPIILCK_00928	6.19e-40	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
NEPIILCK_00929	4.65e-140	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
NEPIILCK_00930	8.18e-94	-	-	-	C	-	-	-	Flavodoxin
NEPIILCK_00931	1.34e-118	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
NEPIILCK_00932	5.57e-75	-	-	-	K	-	-	-	Virulence activator alpha C-term
NEPIILCK_00933	6.71e-220	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
NEPIILCK_00934	8.09e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
NEPIILCK_00935	4.13e-197	-	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_00936	2.6e-201	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
NEPIILCK_00937	1.13e-81	-	-	-	-	-	-	-	-
NEPIILCK_00938	1.7e-167	-	-	-	F	-	-	-	glutamine amidotransferase
NEPIILCK_00940	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
NEPIILCK_00941	1.43e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
NEPIILCK_00942	9.51e-39	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
NEPIILCK_00943	9.85e-116	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
NEPIILCK_00944	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
NEPIILCK_00945	2.06e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
NEPIILCK_00946	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
NEPIILCK_00947	4.7e-263	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NEPIILCK_00948	4.41e-289	-	-	-	-	-	-	-	-
NEPIILCK_00949	4.04e-103	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NEPIILCK_00950	2.16e-136	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NEPIILCK_00951	1.85e-67	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NEPIILCK_00952	2e-14	-	-	-	GM	-	-	-	NmrA-like family
NEPIILCK_00953	4.78e-95	-	-	-	S	ko:K02348	-	ko00000	Gnat family
NEPIILCK_00954	7.72e-51	-	-	-	S	-	-	-	Cytochrome B5
NEPIILCK_00955	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
NEPIILCK_00956	1.29e-53	-	-	-	S	-	-	-	Cytochrome B5
NEPIILCK_00957	1.17e-270	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NEPIILCK_00958	4e-234	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NEPIILCK_00959	1.72e-315	-	-	-	E	ko:K03294	-	ko00000	amino acid
NEPIILCK_00960	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
NEPIILCK_00961	2.62e-25	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NEPIILCK_00962	6.56e-148	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NEPIILCK_00963	5.72e-40	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
NEPIILCK_00965	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NEPIILCK_00966	1.31e-75	-	-	-	-	-	-	-	-
NEPIILCK_00967	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NEPIILCK_00968	1.41e-243	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
NEPIILCK_00969	1.07e-112	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
NEPIILCK_00970	1.38e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
NEPIILCK_00971	1.21e-147	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00972	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_00973	4.81e-50	-	-	-	-	-	-	-	-
NEPIILCK_00974	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
NEPIILCK_00975	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEPIILCK_00976	1.94e-24	-	-	-	-	-	-	-	-
NEPIILCK_00977	0.00028	-	-	-	D	-	-	-	nuclear chromosome segregation
NEPIILCK_00979	9.82e-54	lytE	-	-	M	-	-	-	Lysin motif
NEPIILCK_00981	2.1e-69	-	-	-	-	-	-	-	-
NEPIILCK_00983	1.65e-148	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
NEPIILCK_00984	1.77e-63	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
NEPIILCK_00985	1.58e-146	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NEPIILCK_00987	3.25e-40	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NEPIILCK_00988	8.64e-61	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
NEPIILCK_00989	2.21e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
NEPIILCK_00990	3.4e-118	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NEPIILCK_00991	7.88e-245	flp	-	-	V	-	-	-	Beta-lactamase
NEPIILCK_00992	2.08e-96	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEPIILCK_00993	1.48e-114	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
NEPIILCK_00994	2.82e-24	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEPIILCK_00995	5.09e-153	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NEPIILCK_00996	4.33e-234	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NEPIILCK_00997	1.19e-311	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
NEPIILCK_00998	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NEPIILCK_00999	6.51e-114	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
NEPIILCK_01000	1.3e-203	-	-	-	S	-	-	-	reductase
NEPIILCK_01002	8.73e-11	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
NEPIILCK_01004	1.3e-71	-	-	-	K	-	-	-	LysR substrate binding domain
NEPIILCK_01005	0.0	-	-	-	S	-	-	-	amidohydrolase
NEPIILCK_01007	1.91e-42	blpT	-	-	-	-	-	-	-
NEPIILCK_01008	1.08e-53	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NEPIILCK_01010	4.09e-167	-	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	dextransucrase activity
NEPIILCK_01011	5.17e-252	yueF	-	-	S	-	-	-	AI-2E family transporter
NEPIILCK_01012	1.67e-54	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NEPIILCK_01013	5.12e-244	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NEPIILCK_01014	1.5e-292	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NEPIILCK_01015	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NEPIILCK_01016	1.05e-293	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NEPIILCK_01017	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NEPIILCK_01018	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NEPIILCK_01019	2.82e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
NEPIILCK_01020	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
NEPIILCK_01024	3.7e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NEPIILCK_01025	2.06e-21	-	-	-	-	-	-	-	-
NEPIILCK_01030	5.56e-34	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
NEPIILCK_01031	1.07e-32	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
NEPIILCK_01032	1.08e-63	-	-	-	L	-	-	-	four-way junction helicase activity
NEPIILCK_01036	4.9e-05	-	-	-	S	-	-	-	YopX protein
NEPIILCK_01051	2.02e-47	-	-	-	-	-	-	-	-
NEPIILCK_01052	1.49e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
NEPIILCK_01053	2.17e-205	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NEPIILCK_01054	3.81e-110	-	-	-	-	-	-	-	-
NEPIILCK_01055	1.06e-235	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NEPIILCK_01056	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
NEPIILCK_01057	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
NEPIILCK_01058	6.4e-314	-	-	-	E	-	-	-	amino acid
NEPIILCK_01059	1.89e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NEPIILCK_01061	1.1e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NEPIILCK_01062	6.29e-129	-	-	-	-	-	-	-	-
NEPIILCK_01063	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NEPIILCK_01064	4.32e-232	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEPIILCK_01070	4.98e-35	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
NEPIILCK_01075	3.19e-21	-	-	-	K	-	-	-	Peptidase S24-like
NEPIILCK_01077	9.11e-94	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEPIILCK_01079	1.6e-07	-	-	-	E	-	-	-	Protein of unknown function (DUF3923)
NEPIILCK_01080	2.46e-63	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
NEPIILCK_01081	5.26e-159	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
NEPIILCK_01082	1.43e-193	epsB	-	-	M	-	-	-	biosynthesis protein
NEPIILCK_01083	4.07e-223	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
NEPIILCK_01084	1.37e-90	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
NEPIILCK_01085	8.63e-165	-	-	-	-	-	-	-	-
NEPIILCK_01086	8.23e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
NEPIILCK_01087	6.59e-48	-	-	-	-	-	-	-	-
NEPIILCK_01088	1.84e-105	-	-	-	-	-	-	-	-
NEPIILCK_01089	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NEPIILCK_01090	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
NEPIILCK_01091	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
NEPIILCK_01092	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NEPIILCK_01095	6.42e-24	-	-	-	UW	-	-	-	Tetratricopeptide repeat
NEPIILCK_01096	0.0	-	-	-	M	-	-	-	family 8
NEPIILCK_01097	0.0	-	-	-	M	-	-	-	family 8
NEPIILCK_01099	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NEPIILCK_01100	0.0	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NEPIILCK_01101	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NEPIILCK_01102	4.93e-212	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
NEPIILCK_01103	0.0	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
NEPIILCK_01104	0.0	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEPIILCK_01105	1.25e-265	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
NEPIILCK_01106	2.41e-50	-	-	-	S	-	-	-	glycosyl transferase family 2
NEPIILCK_01107	1.14e-37	-	-	-	S	-	-	-	glycosyl transferase family 2
NEPIILCK_01108	4.73e-241	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEPIILCK_01109	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NEPIILCK_01110	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
NEPIILCK_01111	6.57e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
NEPIILCK_01112	2.27e-191	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NEPIILCK_01113	2.3e-150	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
NEPIILCK_01115	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NEPIILCK_01116	1.59e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
NEPIILCK_01117	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
NEPIILCK_01118	3.69e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NEPIILCK_01119	1.15e-282	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
NEPIILCK_01120	9.1e-184	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
NEPIILCK_01121	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
NEPIILCK_01122	6.04e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NEPIILCK_01123	3.34e-128	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
NEPIILCK_01124	5.26e-203	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
NEPIILCK_01125	3.38e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NEPIILCK_01126	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
NEPIILCK_01127	4.52e-106	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
NEPIILCK_01128	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NEPIILCK_01129	7.88e-304	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
NEPIILCK_01130	4.46e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
NEPIILCK_01131	3.02e-179	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
NEPIILCK_01132	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPIILCK_01133	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NEPIILCK_01134	3.69e-92	-	-	-	-	-	-	-	-
NEPIILCK_01135	5.83e-133	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
NEPIILCK_01136	6.27e-155	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NEPIILCK_01137	1.06e-193	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NEPIILCK_01138	2.26e-23	-	-	-	-	-	-	-	-
NEPIILCK_01139	7.05e-54	-	-	-	-	-	-	-	-
NEPIILCK_01140	5.12e-120	-	-	-	-	-	-	-	-
NEPIILCK_01142	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NEPIILCK_01143	5.83e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NEPIILCK_01144	7.1e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NEPIILCK_01145	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NEPIILCK_01146	6.35e-146	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
NEPIILCK_01147	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
NEPIILCK_01148	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
NEPIILCK_01149	1.69e-233	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NEPIILCK_01151	1.24e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
NEPIILCK_01152	7.3e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
NEPIILCK_01153	2.39e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEPIILCK_01155	1.16e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NEPIILCK_01156	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NEPIILCK_01157	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NEPIILCK_01158	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_01159	4.73e-241	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEPIILCK_01160	3.26e-63	-	-	-	-	-	-	-	-
NEPIILCK_01161	1.98e-196	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEPIILCK_01162	9.24e-186	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
NEPIILCK_01163	4.36e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
NEPIILCK_01164	3.98e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
NEPIILCK_01166	2.57e-223	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
NEPIILCK_01167	4.28e-92	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
NEPIILCK_01168	3.37e-111	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NEPIILCK_01169	1.62e-22	-	-	-	L	-	-	-	Phage integrase family
NEPIILCK_01170	3.39e-187	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NEPIILCK_01171	5.7e-153	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NEPIILCK_01172	1.61e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
NEPIILCK_01173	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NEPIILCK_01174	2.3e-142	-	-	-	I	-	-	-	Acid phosphatase homologues
NEPIILCK_01176	7.19e-198	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NEPIILCK_01179	3.34e-52	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NEPIILCK_01180	0.0	-	-	-	S	ko:K07459	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
NEPIILCK_01181	1.07e-263	-	-	-	L	-	-	-	DNA helicase
NEPIILCK_01182	5.15e-219	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NEPIILCK_01183	2.6e-33	-	-	-	-	-	-	-	-
NEPIILCK_01184	2.43e-145	-	-	-	-	-	-	-	-
NEPIILCK_01185	1.2e-267	yttB	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_01186	9.3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NEPIILCK_01187	7.05e-113	-	-	-	-	-	-	-	-
NEPIILCK_01188	3.39e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NEPIILCK_01189	1.06e-208	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
NEPIILCK_01190	4.33e-76	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
NEPIILCK_01191	5.31e-32	-	-	-	N	ko:K07339	-	ko00000,ko01000,ko02048	mRNA binding
NEPIILCK_01194	7.52e-148	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
NEPIILCK_01195	1.62e-45	-	-	-	L	-	-	-	HNH endonuclease domain protein
NEPIILCK_01196	2.89e-247	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
NEPIILCK_01197	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NEPIILCK_01198	2.2e-19	-	-	-	IQ	-	-	-	KR domain
NEPIILCK_01200	8.49e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
NEPIILCK_01201	5.13e-60	-	-	-	-	-	-	-	-
NEPIILCK_01202	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NEPIILCK_01203	2.58e-41	-	-	-	-	-	-	-	-
NEPIILCK_01204	7.67e-63	-	-	-	-	-	-	-	-
NEPIILCK_01205	3.42e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NEPIILCK_01206	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NEPIILCK_01207	2.69e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
NEPIILCK_01208	4.12e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
NEPIILCK_01209	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NEPIILCK_01210	3.97e-125	-	-	-	-	-	-	-	-
NEPIILCK_01211	3.09e-35	-	-	-	-	-	-	-	-
NEPIILCK_01212	2.71e-81	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NEPIILCK_01213	1.32e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
NEPIILCK_01215	5.29e-65	-	-	-	-	-	-	-	-
NEPIILCK_01216	3.67e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NEPIILCK_01217	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
NEPIILCK_01218	2.32e-109	-	-	-	F	-	-	-	NUDIX domain
NEPIILCK_01219	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEPIILCK_01220	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NEPIILCK_01221	1.56e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NEPIILCK_01222	1.17e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NEPIILCK_01223	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NEPIILCK_01224	7.52e-205	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
NEPIILCK_01225	5.03e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEPIILCK_01226	5.1e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NEPIILCK_01227	7.68e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
NEPIILCK_01228	2.85e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
NEPIILCK_01229	1.32e-218	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NEPIILCK_01230	2.6e-195	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
NEPIILCK_01231	4.3e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
NEPIILCK_01232	1.88e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NEPIILCK_01233	2.44e-245	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NEPIILCK_01234	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_01235	1.65e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NEPIILCK_01236	9.5e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
NEPIILCK_01237	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NEPIILCK_01238	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NEPIILCK_01239	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NEPIILCK_01240	1.66e-147	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NEPIILCK_01241	1.37e-69	-	-	-	M	-	-	-	Lysin motif
NEPIILCK_01242	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
NEPIILCK_01243	3.32e-240	-	-	-	S	-	-	-	Helix-turn-helix domain
NEPIILCK_01244	1.08e-132	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NEPIILCK_01245	5.59e-120	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NEPIILCK_01246	3.58e-208	-	-	-	S	-	-	-	Tetratricopeptide repeat
NEPIILCK_01247	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NEPIILCK_01248	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NEPIILCK_01249	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NEPIILCK_01250	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NEPIILCK_01251	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
NEPIILCK_01252	2.32e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
NEPIILCK_01253	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
NEPIILCK_01254	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NEPIILCK_01255	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NEPIILCK_01256	1.93e-84	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
NEPIILCK_01257	8.27e-141	-	-	-	K	ko:K03091	-	ko00000,ko03021	RNA polymerase sigma factor, sigma-70 family
NEPIILCK_01258	2.51e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NEPIILCK_01259	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NEPIILCK_01260	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NEPIILCK_01261	3.45e-207	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEPIILCK_01262	4.73e-38	-	-	-	L	-	-	-	Transposase
NEPIILCK_01263	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
NEPIILCK_01264	5.93e-265	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NEPIILCK_01265	1.56e-154	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NEPIILCK_01266	1.17e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NEPIILCK_01267	9.22e-104	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
NEPIILCK_01269	4.47e-116	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NEPIILCK_01270	8.64e-49	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
NEPIILCK_01271	1.54e-307	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
NEPIILCK_01272	1.61e-114	-	-	-	-	-	-	-	-
NEPIILCK_01273	2.07e-156	pnb	-	-	C	-	-	-	nitroreductase
NEPIILCK_01274	3.41e-30	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
NEPIILCK_01275	7.66e-154	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
NEPIILCK_01276	0.0	res	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
NEPIILCK_01277	6.79e-44	-	-	-	K	-	-	-	DNA binding
NEPIILCK_01278	6.83e-87	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
NEPIILCK_01279	1.45e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NEPIILCK_01280	5.03e-166	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NEPIILCK_01281	9.16e-202	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NEPIILCK_01282	1.11e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NEPIILCK_01283	2.34e-51	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEPIILCK_01284	3.2e-68	-	-	-	-	-	-	-	-
NEPIILCK_01285	5.22e-177	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
NEPIILCK_01286	1.6e-80	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
NEPIILCK_01287	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NEPIILCK_01288	1.97e-280	arcT	-	-	E	-	-	-	Aminotransferase
NEPIILCK_01289	1e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
NEPIILCK_01290	5.49e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NEPIILCK_01291	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NEPIILCK_01292	3.46e-305	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NEPIILCK_01293	5.76e-228	-	-	-	-	-	-	-	-
NEPIILCK_01294	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEPIILCK_01295	1.31e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NEPIILCK_01296	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NEPIILCK_01297	1.13e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NEPIILCK_01298	2.73e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NEPIILCK_01299	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NEPIILCK_01300	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEPIILCK_01301	3.84e-161	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEPIILCK_01302	1.84e-49	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NEPIILCK_01303	7.43e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NEPIILCK_01304	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NEPIILCK_01305	6.36e-278	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NEPIILCK_01306	5.18e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NEPIILCK_01307	7.09e-163	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
NEPIILCK_01308	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
NEPIILCK_01309	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
NEPIILCK_01310	9.6e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
NEPIILCK_01311	2.33e-291	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
NEPIILCK_01312	7.47e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
NEPIILCK_01313	2.61e-148	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NEPIILCK_01314	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NEPIILCK_01315	3.93e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NEPIILCK_01316	4.11e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NEPIILCK_01317	7.35e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NEPIILCK_01318	1.44e-179	-	-	-	K	-	-	-	LysR substrate binding domain
NEPIILCK_01319	9.94e-71	-	-	-	S	-	-	-	branched-chain amino acid
NEPIILCK_01320	1.32e-183	-	-	-	E	-	-	-	AzlC protein
NEPIILCK_01321	1.85e-264	hpk31	-	-	T	-	-	-	Histidine kinase
NEPIILCK_01322	9.76e-161	vanR	-	-	K	-	-	-	response regulator
NEPIILCK_01323	6.97e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NEPIILCK_01324	1.54e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
NEPIILCK_01325	1.89e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NEPIILCK_01326	1.65e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
NEPIILCK_01327	2.8e-299	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NEPIILCK_01328	8.01e-153	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NEPIILCK_01329	4.25e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NEPIILCK_01330	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NEPIILCK_01331	1.17e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
NEPIILCK_01332	2.79e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NEPIILCK_01333	2.79e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
NEPIILCK_01334	6.46e-201	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NEPIILCK_01335	9.32e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
NEPIILCK_01336	2.08e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
NEPIILCK_01337	4.78e-218	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
NEPIILCK_01338	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
NEPIILCK_01339	9.77e-27	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
NEPIILCK_01341	1.91e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
NEPIILCK_01343	4.86e-07	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
NEPIILCK_01344	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEPIILCK_01345	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_01347	5.06e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NEPIILCK_01348	5.58e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
NEPIILCK_01349	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
NEPIILCK_01350	3.5e-272	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
NEPIILCK_01351	9.73e-69	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
NEPIILCK_01352	1.72e-246	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
NEPIILCK_01354	7.24e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
NEPIILCK_01355	4.68e-152	-	-	-	L	-	-	-	Integrase
NEPIILCK_01356	1.01e-223	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NEPIILCK_01357	9.84e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NEPIILCK_01358	3.69e-150	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
NEPIILCK_01359	2.41e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
NEPIILCK_01360	2.01e-08	-	-	-	-	-	-	-	-
NEPIILCK_01366	7.05e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NEPIILCK_01367	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NEPIILCK_01368	1.21e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NEPIILCK_01369	1.1e-312	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NEPIILCK_01370	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NEPIILCK_01371	2.38e-68	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NEPIILCK_01372	7.27e-272	isp	-	-	L	-	-	-	Transposase
NEPIILCK_01373	1.7e-116	-	-	-	L	-	-	-	Integrase
NEPIILCK_01374	2.47e-112	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NEPIILCK_01375	2.02e-22	-	-	-	K	-	-	-	Transcriptional regulator, LacI family
NEPIILCK_01376	2.05e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEPIILCK_01377	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NEPIILCK_01378	1.76e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NEPIILCK_01379	4.01e-63	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NEPIILCK_01380	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NEPIILCK_01381	1.09e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NEPIILCK_01382	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NEPIILCK_01383	4.68e-117	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NEPIILCK_01384	4.58e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NEPIILCK_01385	1.26e-84	-	-	-	-	-	-	-	-
NEPIILCK_01386	3.65e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NEPIILCK_01387	1.16e-213	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NEPIILCK_01388	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NEPIILCK_01389	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NEPIILCK_01390	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
NEPIILCK_01391	1.2e-59	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
NEPIILCK_01392	1.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NEPIILCK_01393	5.44e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NEPIILCK_01394	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NEPIILCK_01395	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NEPIILCK_01396	8.1e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NEPIILCK_01397	8.28e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NEPIILCK_01398	7.14e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NEPIILCK_01399	4.23e-123	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NEPIILCK_01400	1.81e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NEPIILCK_01401	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NEPIILCK_01402	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NEPIILCK_01403	1.69e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEPIILCK_01404	3.79e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
NEPIILCK_01405	5.67e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
NEPIILCK_01406	3.72e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
NEPIILCK_01407	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
NEPIILCK_01408	2.22e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
NEPIILCK_01409	4.18e-147	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NEPIILCK_01410	3.35e-269	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
NEPIILCK_01411	1.1e-158	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NEPIILCK_01414	1.83e-19	-	-	-	-	-	-	-	-
NEPIILCK_01415	3.31e-20	-	-	-	-	-	-	-	-
NEPIILCK_01417	3.5e-195	-	-	-	M	-	-	-	MucBP domain
NEPIILCK_01418	1.53e-122	-	-	-	-	-	-	-	-
NEPIILCK_01419	1.77e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NEPIILCK_01420	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NEPIILCK_01421	3.87e-200	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NEPIILCK_01422	1.38e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NEPIILCK_01423	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NEPIILCK_01424	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NEPIILCK_01425	4.87e-209	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NEPIILCK_01427	2.9e-149	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
NEPIILCK_01428	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
NEPIILCK_01429	8.44e-67	-	-	-	-	-	-	-	-
NEPIILCK_01430	1.51e-259	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NEPIILCK_01431	2.1e-37	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
NEPIILCK_01432	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
NEPIILCK_01433	1.37e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NEPIILCK_01434	1.52e-141	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
NEPIILCK_01435	2.73e-148	-	-	-	M	-	-	-	LysM domain protein
NEPIILCK_01436	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
NEPIILCK_01437	3.93e-138	-	-	-	M	-	-	-	LysM domain protein
NEPIILCK_01438	2.83e-190	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NEPIILCK_01439	1.09e-143	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NEPIILCK_01440	5.26e-188	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
NEPIILCK_01441	8.69e-195	yeaE	-	-	S	-	-	-	Aldo keto
NEPIILCK_01442	1.89e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NEPIILCK_01443	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
NEPIILCK_01444	4.58e-103	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
NEPIILCK_01445	4.13e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
NEPIILCK_01446	7.03e-33	-	-	-	-	-	-	-	-
NEPIILCK_01447	8.28e-135	-	-	-	V	-	-	-	VanZ like family
NEPIILCK_01448	6.7e-301	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
NEPIILCK_01449	2.08e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NEPIILCK_01450	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_01451	7.72e-122	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
NEPIILCK_01452	1.34e-280	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NEPIILCK_01453	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NEPIILCK_01454	8.74e-57	-	-	-	-	-	-	-	-
NEPIILCK_01455	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
NEPIILCK_01456	1.37e-45	-	-	-	-	-	-	-	-
NEPIILCK_01457	4.78e-35	-	-	-	-	-	-	-	-
NEPIILCK_01459	4.7e-25	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NEPIILCK_01460	2.14e-197	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NEPIILCK_01461	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
NEPIILCK_01462	1.08e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
NEPIILCK_01463	4.51e-224	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NEPIILCK_01464	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
NEPIILCK_01465	1.26e-145	-	-	-	-	-	-	-	-
NEPIILCK_01466	3.58e-238	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
NEPIILCK_01467	8.09e-208	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NEPIILCK_01468	1.52e-43	-	-	-	-	-	-	-	-
NEPIILCK_01469	1.43e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NEPIILCK_01470	9.17e-59	-	-	-	-	-	-	-	-
NEPIILCK_01472	5.18e-72	-	-	-	-	-	-	-	-
NEPIILCK_01473	2.13e-185	-	-	-	S	-	-	-	Domain of unknown function DUF1829
NEPIILCK_01474	8.27e-96	-	-	-	-	-	-	-	-
NEPIILCK_01475	1.22e-74	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NEPIILCK_01476	5.53e-122	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NEPIILCK_01477	7.92e-135	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
NEPIILCK_01478	1.51e-280	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NEPIILCK_01479	8.24e-133	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
NEPIILCK_01480	2.03e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
NEPIILCK_01481	1.32e-60	-	-	-	-	-	-	-	-
NEPIILCK_01482	1.49e-54	-	-	-	-	-	-	-	-
NEPIILCK_01484	1.67e-99	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NEPIILCK_01485	1.28e-232	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
NEPIILCK_01486	3.53e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
NEPIILCK_01496	2.7e-263	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
NEPIILCK_01497	4.16e-165	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
NEPIILCK_01498	1.84e-130	-	-	-	-	-	-	-	-
NEPIILCK_01503	9.54e-113	-	-	-	S	-	-	-	Protein conserved in bacteria
NEPIILCK_01504	2.13e-232	-	-	-	-	-	-	-	-
NEPIILCK_01505	4.87e-203	-	-	-	-	-	-	-	-
NEPIILCK_01506	1.16e-143	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NEPIILCK_01507	3.19e-55	-	-	-	CQ	-	-	-	BMC
NEPIILCK_01508	3.41e-170	pduB	-	-	E	-	-	-	BMC
NEPIILCK_01509	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
NEPIILCK_01510	6.34e-165	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
NEPIILCK_01511	1.1e-106	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
NEPIILCK_01512	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
NEPIILCK_01513	4.82e-78	pduH	-	-	S	-	-	-	Dehydratase medium subunit
NEPIILCK_01514	3.28e-112	-	-	-	CQ	-	-	-	BMC
NEPIILCK_01515	2.38e-56	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
NEPIILCK_01516	1.77e-151	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NEPIILCK_01517	2.75e-116	-	-	-	S	-	-	-	Putative propanediol utilisation
NEPIILCK_01518	1.96e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
NEPIILCK_01519	1.26e-137	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
NEPIILCK_01520	1.01e-104	pduO	-	-	S	-	-	-	Haem-degrading
NEPIILCK_01521	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
NEPIILCK_01522	6.52e-270	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
NEPIILCK_01523	7.5e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEPIILCK_01524	3.32e-74	-	-	-	E	ko:K04031	-	ko00000	BMC
NEPIILCK_01525	2.32e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
NEPIILCK_01526	6.68e-156	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
NEPIILCK_01527	1.64e-110	-	-	-	P	-	-	-	Cadmium resistance transporter
NEPIILCK_01528	7.7e-95	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
NEPIILCK_01529	2.54e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NEPIILCK_01530	2.32e-198	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
NEPIILCK_01531	7.96e-133	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
NEPIILCK_01532	1.47e-265	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
NEPIILCK_01533	0.0	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NEPIILCK_01534	1.33e-228	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NEPIILCK_01535	2.8e-159	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
NEPIILCK_01536	2.46e-270	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NEPIILCK_01537	2.01e-141	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NEPIILCK_01538	2.89e-124	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NEPIILCK_01539	3.78e-170	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NEPIILCK_01540	8.21e-246	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
NEPIILCK_01541	3.53e-169	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NEPIILCK_01542	3e-171	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
NEPIILCK_01543	0.0	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NEPIILCK_01544	6.89e-185	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
NEPIILCK_01545	2.02e-157	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
NEPIILCK_01546	8.97e-171	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NEPIILCK_01547	2.56e-70	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NEPIILCK_01548	1.43e-151	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NEPIILCK_01549	5.9e-190	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
NEPIILCK_01550	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NEPIILCK_01551	1.11e-101	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
NEPIILCK_01552	1.88e-291	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NEPIILCK_01553	1.78e-210	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NEPIILCK_01554	1.56e-229	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
NEPIILCK_01555	0.0	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NEPIILCK_01556	1.71e-131	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
NEPIILCK_01557	3.94e-172	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NEPIILCK_01558	3.23e-145	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
NEPIILCK_01559	3.41e-169	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
NEPIILCK_01560	9.25e-247	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NEPIILCK_01561	2.94e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
NEPIILCK_01562	1.68e-115	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
NEPIILCK_01563	1.04e-67	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
NEPIILCK_01564	1.78e-58	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NEPIILCK_01565	2.4e-53	-	-	-	L	-	-	-	PFAM Integrase catalytic region
NEPIILCK_01566	4.41e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
NEPIILCK_01567	5.71e-131	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NEPIILCK_01568	6.42e-139	-	-	-	L	-	-	-	nuclease
NEPIILCK_01570	7.4e-130	comA	-	-	V	ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEPIILCK_01571	1.37e-165	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NEPIILCK_01572	2.54e-286	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NEPIILCK_01573	3.96e-76	-	-	-	-	-	-	-	-
NEPIILCK_01574	2.09e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NEPIILCK_01575	3.48e-86	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
NEPIILCK_01576	1.61e-81	-	-	-	S	-	-	-	macrophage migration inhibitory factor
NEPIILCK_01577	2.63e-214	-	-	-	C	-	-	-	Oxidoreductase
NEPIILCK_01580	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
NEPIILCK_01581	1.32e-112	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NEPIILCK_01582	1.95e-64	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NEPIILCK_01585	3.98e-146	-	-	-	-	-	-	-	-
NEPIILCK_01586	0.0	-	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_01587	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
NEPIILCK_01588	1.28e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
NEPIILCK_01589	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
NEPIILCK_01590	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NEPIILCK_01591	1.58e-198	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NEPIILCK_01592	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
NEPIILCK_01593	1.93e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NEPIILCK_01595	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
NEPIILCK_01596	8.74e-234	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
NEPIILCK_01597	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
NEPIILCK_01598	1.76e-171	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NEPIILCK_01599	1.54e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
NEPIILCK_01600	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NEPIILCK_01601	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEPIILCK_01602	3.52e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_01603	3.51e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NEPIILCK_01604	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
NEPIILCK_01605	7.17e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NEPIILCK_01606	1.93e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NEPIILCK_01607	3.42e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
NEPIILCK_01608	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NEPIILCK_01609	5.99e-266	yacL	-	-	S	-	-	-	domain protein
NEPIILCK_01610	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NEPIILCK_01611	2.52e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NEPIILCK_01612	2.59e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NEPIILCK_01613	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NEPIILCK_01614	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NEPIILCK_01615	8.03e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NEPIILCK_01616	2.38e-157	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NEPIILCK_01618	1.03e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
NEPIILCK_01621	3.81e-98	-	-	-	S	-	-	-	Fic/DOC family
NEPIILCK_01622	9.98e-64	-	-	-	E	-	-	-	Filamentation induced by cAMP protein fic
NEPIILCK_01625	5.39e-64	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
NEPIILCK_01626	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NEPIILCK_01628	2.25e-284	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
NEPIILCK_01629	5.86e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NEPIILCK_01630	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NEPIILCK_01631	2.62e-204	-	-	-	EG	-	-	-	EamA-like transporter family
NEPIILCK_01632	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NEPIILCK_01633	2.69e-311	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NEPIILCK_01634	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NEPIILCK_01635	2.31e-148	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
NEPIILCK_01636	4.71e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
NEPIILCK_01637	1.24e-298	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NEPIILCK_01638	1.34e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
NEPIILCK_01639	6.08e-13	-	-	-	S	-	-	-	CsbD-like
NEPIILCK_01640	1.05e-228	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEPIILCK_01641	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
NEPIILCK_01642	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
NEPIILCK_01643	2.91e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NEPIILCK_01644	3.82e-192	-	-	-	-	-	-	-	-
NEPIILCK_01645	6.63e-33	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
NEPIILCK_01646	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NEPIILCK_01647	1.11e-127	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
NEPIILCK_01648	5.1e-97	-	-	-	F	-	-	-	Nudix hydrolase
NEPIILCK_01649	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
NEPIILCK_01650	5.29e-300	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
NEPIILCK_01651	3.4e-294	-	-	-	-	-	-	-	-
NEPIILCK_01652	4.21e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NEPIILCK_01653	5.16e-182	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NEPIILCK_01654	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NEPIILCK_01655	2.94e-261	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NEPIILCK_01656	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NEPIILCK_01657	2.13e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
NEPIILCK_01658	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
NEPIILCK_01659	6.91e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NEPIILCK_01660	8.81e-317	yagE	-	-	E	-	-	-	amino acid
NEPIILCK_01661	3.4e-145	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
NEPIILCK_01662	4.85e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NEPIILCK_01663	2.71e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NEPIILCK_01683	3.05e-16	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEPIILCK_01684	3.78e-49	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
NEPIILCK_01688	7.98e-18	-	-	-	L	-	-	-	Helix-turn-helix domain
NEPIILCK_01689	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
NEPIILCK_01690	7.6e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
NEPIILCK_01691	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
NEPIILCK_01692	3.09e-62	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
NEPIILCK_01693	5.16e-215	-	-	-	C	-	-	-	Aldo keto reductase
NEPIILCK_01694	6.13e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
NEPIILCK_01695	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
NEPIILCK_01696	8.72e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
NEPIILCK_01697	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
NEPIILCK_01698	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
NEPIILCK_01699	1.45e-262	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NEPIILCK_01700	1.17e-220	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NEPIILCK_01701	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NEPIILCK_01702	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NEPIILCK_01703	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NEPIILCK_01704	2.02e-138	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
NEPIILCK_01706	1.03e-208	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NEPIILCK_01707	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
NEPIILCK_01708	8.68e-44	-	-	-	-	-	-	-	-
NEPIILCK_01709	1.04e-268	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NEPIILCK_01710	1.54e-224	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NEPIILCK_01711	2.39e-98	-	-	-	O	-	-	-	OsmC-like protein
NEPIILCK_01713	5.67e-309	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NEPIILCK_01715	9.01e-179	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
NEPIILCK_01716	1.85e-301	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
NEPIILCK_01718	8.56e-236	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
NEPIILCK_01719	5.7e-146	-	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_01720	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NEPIILCK_01721	1.77e-72	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
NEPIILCK_01722	7.2e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NEPIILCK_01723	7.14e-166	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NEPIILCK_01724	4.13e-254	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NEPIILCK_01725	9.21e-143	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
NEPIILCK_01726	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
NEPIILCK_01727	2.24e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NEPIILCK_01728	6.56e-192	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NEPIILCK_01729	4.26e-307	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEPIILCK_01730	2.83e-58	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NEPIILCK_01731	6.13e-199	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NEPIILCK_01732	9.79e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
NEPIILCK_01733	4.54e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NEPIILCK_01734	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NEPIILCK_01735	7.4e-71	-	-	-	-	-	-	-	-
NEPIILCK_01736	4.37e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NEPIILCK_01737	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NEPIILCK_01738	2.74e-267	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NEPIILCK_01739	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NEPIILCK_01740	4.98e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NEPIILCK_01741	1.63e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NEPIILCK_01742	8.61e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NEPIILCK_01743	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NEPIILCK_01744	1.03e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NEPIILCK_01745	1.83e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NEPIILCK_01746	1.35e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
NEPIILCK_01747	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NEPIILCK_01748	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
NEPIILCK_01749	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
NEPIILCK_01750	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NEPIILCK_01751	5.28e-238	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NEPIILCK_01752	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NEPIILCK_01753	5.24e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NEPIILCK_01754	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NEPIILCK_01755	5.07e-282	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NEPIILCK_01756	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NEPIILCK_01757	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NEPIILCK_01758	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NEPIILCK_01759	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NEPIILCK_01760	2.09e-116	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NEPIILCK_01761	7.76e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NEPIILCK_01762	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
NEPIILCK_01763	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NEPIILCK_01764	2.81e-59	-	-	-	P	ko:K02031,ko:K02032,ko:K10823,ko:K13892,ko:K13896,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NEPIILCK_01765	1.95e-290	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NEPIILCK_01766	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NEPIILCK_01767	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NEPIILCK_01768	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NEPIILCK_01769	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NEPIILCK_01770	2.15e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NEPIILCK_01771	2.86e-244	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NEPIILCK_01772	2.05e-256	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NEPIILCK_01773	6.17e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
NEPIILCK_01774	2.06e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
NEPIILCK_01775	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NEPIILCK_01776	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NEPIILCK_01777	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NEPIILCK_01778	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NEPIILCK_01779	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NEPIILCK_01780	8.35e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
NEPIILCK_01781	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NEPIILCK_01782	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NEPIILCK_01783	8.27e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NEPIILCK_01784	2.21e-185	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NEPIILCK_01785	4.93e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NEPIILCK_01786	1.51e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NEPIILCK_01787	3.62e-100	ykuL	-	-	S	-	-	-	(CBS) domain
NEPIILCK_01788	1.91e-196	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
NEPIILCK_01789	2.65e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
NEPIILCK_01790	1.04e-69	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NEPIILCK_01791	3.65e-47	-	-	-	-	-	-	-	-
NEPIILCK_01792	2.18e-269	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NEPIILCK_01793	2.41e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NEPIILCK_01794	2.32e-178	-	-	-	-	-	-	-	-
NEPIILCK_01795	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
NEPIILCK_01796	1.7e-234	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
NEPIILCK_01797	1.75e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
NEPIILCK_01798	1.49e-60	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
NEPIILCK_01799	1.01e-100	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
NEPIILCK_01800	2.78e-55	-	-	-	-	-	-	-	-
NEPIILCK_01801	7.66e-91	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
NEPIILCK_01802	1.46e-185	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
NEPIILCK_01803	5.54e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NEPIILCK_01804	3.48e-152	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NEPIILCK_01805	4.3e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
NEPIILCK_01806	5.87e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NEPIILCK_01807	9.74e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
NEPIILCK_01808	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
NEPIILCK_01809	2.65e-161	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
NEPIILCK_01810	5.97e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NEPIILCK_01812	1.11e-192	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
NEPIILCK_01813	2.6e-96	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
NEPIILCK_01814	5.89e-71	-	-	-	S	-	-	-	Bacteriophage holin family
NEPIILCK_01817	6.62e-49	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
NEPIILCK_01820	0.0	-	-	-	M	-	-	-	CHAP domain
NEPIILCK_01821	4.86e-214	-	-	-	S	-	-	-	Phage tail protein
NEPIILCK_01822	1.08e-226	-	-	-	D	-	-	-	domain protein
NEPIILCK_01823	6.07e-120	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
NEPIILCK_01824	5.93e-155	-	-	-	-	-	-	-	-
NEPIILCK_01825	1.35e-92	-	-	-	-	-	-	-	-
NEPIILCK_01826	1.65e-115	-	-	-	-	-	-	-	-
NEPIILCK_01827	2.28e-60	-	-	-	-	-	-	-	-
NEPIILCK_01828	8.26e-80	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NEPIILCK_01829	1.32e-250	gpG	-	-	-	-	-	-	-
NEPIILCK_01830	8.07e-129	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
NEPIILCK_01832	1.85e-213	-	-	-	S	-	-	-	Phage Mu protein F like protein
NEPIILCK_01833	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NEPIILCK_01834	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
NEPIILCK_01836	6.49e-154	-	-	-	K	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
NEPIILCK_01838	2.58e-88	-	-	-	-	-	-	-	-
NEPIILCK_01839	1.76e-155	-	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	sulfate reduction
NEPIILCK_01840	7.73e-109	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
NEPIILCK_01843	9.96e-23	-	-	-	-	-	-	-	-
NEPIILCK_01846	2.75e-21	-	-	-	-	-	-	-	-
NEPIILCK_01847	5.51e-106	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
NEPIILCK_01849	1.72e-67	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
NEPIILCK_01850	8.24e-22	-	-	-	-	-	-	-	-
NEPIILCK_01855	5.21e-47	-	-	-	L	-	-	-	DnaD domain protein
NEPIILCK_01856	2.16e-191	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
NEPIILCK_01857	5.46e-207	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
NEPIILCK_01865	1.88e-11	-	-	-	-	-	-	-	-
NEPIILCK_01866	9e-66	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEPIILCK_01872	1.63e-39	-	-	-	-	-	-	-	-
NEPIILCK_01874	1.83e-60	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
NEPIILCK_01875	1.95e-115	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NEPIILCK_01877	7.66e-07	-	2.7.13.3, 2.7.7.7, 5.4.99.21	-	D	ko:K02343,ko:K03407,ko:K06182,ko:K08372,ko:K12065,ko:K16291	ko00230,ko00240,ko01100,ko02020,ko02030,ko03030,ko03430,ko03440,map00230,map00240,map01100,map02020,map02030,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko01001,ko01002,ko01011,ko02022,ko02035,ko02044,ko03009,ko03032,ko03400	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NEPIILCK_01878	8.96e-33	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
NEPIILCK_01880	6.76e-63	-	-	-	L	-	-	-	Protein of unknown function (DUF3991)
NEPIILCK_01881	7.04e-162	topA2	5.99.1.2	-	G	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
NEPIILCK_01883	4.42e-180	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NEPIILCK_01888	1.82e-230	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
NEPIILCK_01892	4.13e-221	-	-	-	U	-	-	-	type IV secretory pathway VirB4
NEPIILCK_01894	2.32e-36	-	-	-	M	-	-	-	Bacteriophage peptidoglycan hydrolase
NEPIILCK_01899	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NEPIILCK_01900	2.53e-240	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NEPIILCK_01901	2.18e-216	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NEPIILCK_01902	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NEPIILCK_01903	3.68e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
NEPIILCK_01904	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NEPIILCK_01905	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
NEPIILCK_01906	8.69e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NEPIILCK_01907	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
NEPIILCK_01908	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NEPIILCK_01909	3.25e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NEPIILCK_01910	3.84e-145	-	-	-	S	-	-	-	(CBS) domain
NEPIILCK_01911	2.4e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
NEPIILCK_01912	2.17e-306	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
NEPIILCK_01913	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
NEPIILCK_01914	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NEPIILCK_01915	3.78e-270	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NEPIILCK_01916	2.57e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NEPIILCK_01917	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
NEPIILCK_01918	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEPIILCK_01919	3.03e-298	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
NEPIILCK_01920	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NEPIILCK_01921	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NEPIILCK_01922	4.04e-211	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NEPIILCK_01923	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
NEPIILCK_01924	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NEPIILCK_01925	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NEPIILCK_01926	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NEPIILCK_01927	2.85e-122	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NEPIILCK_01928	1.15e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NEPIILCK_01929	3.7e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
NEPIILCK_01930	3.34e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
NEPIILCK_01931	4.1e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NEPIILCK_01932	2.48e-161	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
NEPIILCK_01933	5.56e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
NEPIILCK_01934	3.91e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NEPIILCK_01935	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NEPIILCK_01936	3.89e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEPIILCK_01937	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NEPIILCK_01938	1.04e-85	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NEPIILCK_01939	9.28e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
NEPIILCK_01940	2.79e-187	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
NEPIILCK_01941	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
NEPIILCK_01942	4.65e-190	yidA	-	-	S	-	-	-	hydrolase
NEPIILCK_01943	2.39e-98	-	-	-	-	-	-	-	-
NEPIILCK_01944	9.36e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEPIILCK_01945	3.17e-314	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NEPIILCK_01946	2.7e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NEPIILCK_01947	3.54e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
NEPIILCK_01948	2.81e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NEPIILCK_01949	4.95e-216	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NEPIILCK_01950	2.34e-204	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NEPIILCK_01951	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
NEPIILCK_01952	1.25e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NEPIILCK_01953	2.87e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NEPIILCK_01954	2.16e-199	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
NEPIILCK_01955	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NEPIILCK_01956	9.56e-208	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
NEPIILCK_01958	1.69e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
NEPIILCK_01959	4.27e-225	-	-	-	-	-	-	-	-
NEPIILCK_01960	7.91e-288	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
NEPIILCK_01961	5.11e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
NEPIILCK_01962	1.85e-241	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NEPIILCK_01963	3.45e-240	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
NEPIILCK_01964	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
NEPIILCK_01965	0.0	-	-	-	L	-	-	-	DNA helicase
NEPIILCK_01966	3.69e-259	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NEPIILCK_01967	2.47e-250	eriC	-	-	P	ko:K03281	-	ko00000	chloride
NEPIILCK_01968	1.49e-190	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NEPIILCK_01969	2.21e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NEPIILCK_01970	1.21e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
NEPIILCK_01971	3.86e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NEPIILCK_01972	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
NEPIILCK_01973	1.05e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
NEPIILCK_01974	4.45e-310	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NEPIILCK_01975	5.05e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
NEPIILCK_01976	7.36e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NEPIILCK_01977	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NEPIILCK_01978	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NEPIILCK_01979	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NEPIILCK_01980	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEPIILCK_01981	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NEPIILCK_01982	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NEPIILCK_01983	5.4e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NEPIILCK_01984	1.62e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
NEPIILCK_01985	1.11e-164	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
NEPIILCK_01986	3.33e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
NEPIILCK_01987	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NEPIILCK_01988	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NEPIILCK_01989	1.49e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NEPIILCK_01990	3.12e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NEPIILCK_01991	2.26e-209	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NEPIILCK_01992	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NEPIILCK_01993	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NEPIILCK_01994	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
NEPIILCK_01995	8.08e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
NEPIILCK_01996	3.26e-296	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
NEPIILCK_01997	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
NEPIILCK_01998	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NEPIILCK_01999	1.78e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
NEPIILCK_02000	2.72e-238	ampC	-	-	V	-	-	-	Beta-lactamase
NEPIILCK_02001	9.26e-77	-	-	-	-	-	-	-	-
NEPIILCK_02002	0.0	-	-	-	M	-	-	-	domain protein
NEPIILCK_02003	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NEPIILCK_02004	1.01e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
NEPIILCK_02005	5.61e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NEPIILCK_02006	6.38e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
NEPIILCK_02007	1.56e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NEPIILCK_02008	4.2e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
NEPIILCK_02009	4.03e-157	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NEPIILCK_02010	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
NEPIILCK_02011	7.41e-277	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
NEPIILCK_02012	1.83e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
NEPIILCK_02013	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NEPIILCK_02014	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NEPIILCK_02015	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NEPIILCK_02016	2.46e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NEPIILCK_02017	7.28e-303	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
NEPIILCK_02018	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NEPIILCK_02019	4.46e-124	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NEPIILCK_02020	7.23e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NEPIILCK_02021	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NEPIILCK_02022	2.05e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
NEPIILCK_02023	7.56e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
NEPIILCK_02024	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NEPIILCK_02025	2.23e-150	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NEPIILCK_02026	2.42e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
NEPIILCK_02027	5.16e-72	-	-	-	S	-	-	-	Small secreted protein
NEPIILCK_02028	6.99e-213	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NEPIILCK_02029	7.11e-228	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NEPIILCK_02030	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NEPIILCK_02031	2.06e-124	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
NEPIILCK_02032	8.85e-51	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
NEPIILCK_02033	2.52e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NEPIILCK_02034	1.1e-277	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NEPIILCK_02035	3.28e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_02036	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
NEPIILCK_02038	3.96e-178	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NEPIILCK_02039	0.0	yhaN	-	-	L	-	-	-	AAA domain
NEPIILCK_02040	1.05e-272	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
NEPIILCK_02041	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NEPIILCK_02042	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NEPIILCK_02043	6.35e-177	-	-	-	IQ	-	-	-	KR domain
NEPIILCK_02044	1.3e-260	fhaB	-	-	M	ko:K15125,ko:K18491	ko04550,ko05133,map04550,map05133	ko00000,ko00001,ko00536,ko03000	translation initiation factor activity
NEPIILCK_02045	0.000617	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
NEPIILCK_02046	5.49e-167	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NEPIILCK_02047	2.61e-282	potE	-	-	E	-	-	-	Amino Acid
NEPIILCK_02048	2.88e-125	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NEPIILCK_02049	8.83e-303	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NEPIILCK_02050	6.57e-144	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NEPIILCK_02051	6.5e-71	-	-	-	-	-	-	-	-
NEPIILCK_02052	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
NEPIILCK_02053	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
NEPIILCK_02054	2.53e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
NEPIILCK_02055	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
NEPIILCK_02056	8.16e-206	-	-	-	-	-	-	-	-
NEPIILCK_02057	1.06e-19	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NEPIILCK_02058	7.42e-95	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NEPIILCK_02059	3.81e-48	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NEPIILCK_02060	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
NEPIILCK_02061	1.37e-270	-	-	-	EGP	-	-	-	Major Facilitator
NEPIILCK_02062	7.9e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NEPIILCK_02063	2.01e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
NEPIILCK_02064	2.31e-11	-	-	-	-	-	-	-	-
NEPIILCK_02065	1.78e-83	-	-	-	-	-	-	-	-
NEPIILCK_02066	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NEPIILCK_02067	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
NEPIILCK_02068	0.0	fusA1	-	-	J	-	-	-	elongation factor G
NEPIILCK_02069	2.65e-214	-	-	-	GK	-	-	-	ROK family
NEPIILCK_02070	2.79e-310	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NEPIILCK_02071	1.02e-176	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
NEPIILCK_02072	7.11e-309	-	-	-	E	-	-	-	amino acid
NEPIILCK_02073	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
NEPIILCK_02074	7.12e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
NEPIILCK_02075	4.96e-222	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NEPIILCK_02076	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NEPIILCK_02077	3.82e-157	-	-	-	S	-	-	-	repeat protein
NEPIILCK_02078	4.69e-158	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
NEPIILCK_02079	1.02e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NEPIILCK_02080	2.27e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
NEPIILCK_02081	9.04e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
NEPIILCK_02082	8.02e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NEPIILCK_02083	1.54e-33	-	-	-	-	-	-	-	-
NEPIILCK_02084	1.44e-128	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NEPIILCK_02085	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
NEPIILCK_02086	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NEPIILCK_02087	3.71e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
NEPIILCK_02088	2.92e-187	ylmH	-	-	S	-	-	-	S4 domain protein
NEPIILCK_02089	3.2e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
NEPIILCK_02090	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NEPIILCK_02091	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NEPIILCK_02092	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NEPIILCK_02093	2.35e-185	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NEPIILCK_02094	3.99e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NEPIILCK_02095	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NEPIILCK_02096	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NEPIILCK_02097	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NEPIILCK_02098	5.99e-74	ftsL	-	-	D	-	-	-	Cell division protein FtsL
NEPIILCK_02099	2.29e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NEPIILCK_02100	8.67e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NEPIILCK_02101	4e-76	-	-	-	-	-	-	-	-
NEPIILCK_02102	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
NEPIILCK_02103	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NEPIILCK_02104	1.03e-121	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NEPIILCK_02105	6.7e-205	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
NEPIILCK_02106	7.98e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
NEPIILCK_02108	2.38e-68	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
NEPIILCK_02109	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
NEPIILCK_02112	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NEPIILCK_02113	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NEPIILCK_02114	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
NEPIILCK_02115	1.86e-241	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
NEPIILCK_02116	3.75e-77	-	-	-	S	-	-	-	COG5546 Small integral membrane protein
NEPIILCK_02117	6.51e-46	-	-	-	-	-	-	-	-
NEPIILCK_02121	3.53e-206	-	-	-	-	-	-	-	-
NEPIILCK_02125	3.18e-19	-	-	-	LM	-	-	-	gp58-like protein
NEPIILCK_02126	2.68e-267	-	-	-	M	-	-	-	Prophage endopeptidase tail
NEPIILCK_02127	3.96e-150	-	-	-	S	-	-	-	Phage tail protein
NEPIILCK_02128	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
NEPIILCK_02130	7.5e-84	-	-	-	S	-	-	-	Phage tail tube protein
NEPIILCK_02131	2.83e-26	-	-	-	-	-	-	-	-
NEPIILCK_02132	5.56e-27	-	-	-	-	-	-	-	-
NEPIILCK_02133	3.56e-50	-	-	-	S	-	-	-	Phage head-tail joining protein
NEPIILCK_02134	4.01e-63	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
NEPIILCK_02135	3.03e-165	-	-	-	S	-	-	-	Phage capsid family
NEPIILCK_02136	7.29e-113	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
NEPIILCK_02137	1.99e-181	-	-	-	S	-	-	-	portal protein
NEPIILCK_02139	0.0	-	-	-	S	-	-	-	Phage Terminase
NEPIILCK_02140	1.99e-104	-	-	-	L	-	-	-	Phage terminase, small subunit
NEPIILCK_02141	3.97e-66	-	-	-	L	-	-	-	HNH nucleases