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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
NHLFHNML_00001	3.84e-162	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
NHLFHNML_00002	3.15e-131	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
NHLFHNML_00003	7.23e-107	ykuV	-	-	CO	-	-	-	thiol-disulfide
NHLFHNML_00004	2.58e-147	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NHLFHNML_00005	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHLFHNML_00006	1.81e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
NHLFHNML_00007	1.44e-128	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHLFHNML_00009	1.46e-131	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
NHLFHNML_00010	7.59e-256	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHLFHNML_00011	2.48e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHLFHNML_00012	6.67e-248	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHLFHNML_00013	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHLFHNML_00014	2.41e-236	appD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_00015	2.15e-235	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_00016	0.0	appA_2	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NHLFHNML_00017	7.93e-222	-	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_00018	1.7e-207	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_00019	1.1e-85	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
NHLFHNML_00020	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NHLFHNML_00021	7.93e-167	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NHLFHNML_00022	1.54e-268	-	-	-	O	-	-	-	Peptidase family M48
NHLFHNML_00023	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
NHLFHNML_00024	2.47e-52	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
NHLFHNML_00025	6.15e-146	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
NHLFHNML_00026	1.2e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
NHLFHNML_00027	1.52e-208	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NHLFHNML_00028	1.13e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
NHLFHNML_00029	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
NHLFHNML_00030	1.01e-66	ylaH	-	-	S	-	-	-	YlaH-like protein
NHLFHNML_00031	1.3e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_00032	0.0	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
NHLFHNML_00033	3.07e-119	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NHLFHNML_00034	1.92e-56	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
NHLFHNML_00035	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NHLFHNML_00036	3.05e-203	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NHLFHNML_00037	2.38e-253	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NHLFHNML_00038	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHLFHNML_00039	7.21e-143	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NHLFHNML_00040	2.95e-68	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NHLFHNML_00041	1.87e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
NHLFHNML_00042	7.94e-109	-	-	-	-	-	-	-	-
NHLFHNML_00043	7.74e-83	ylbA	-	-	S	-	-	-	YugN-like family
NHLFHNML_00044	1.31e-248	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
NHLFHNML_00045	1.38e-108	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein, possibly involved in aromatic compounds catabolism
NHLFHNML_00046	1.09e-91	ylbD	-	-	S	-	-	-	Putative coat protein
NHLFHNML_00047	7.5e-43	ylbE	-	-	S	-	-	-	YlbE-like protein
NHLFHNML_00048	2.29e-177	-	-	-	HJ	ko:K05844	-	ko00000,ko01000,ko03009	Prokaryotic glutathione synthetase, ATP-grasp domain
NHLFHNML_00049	1.36e-90	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
NHLFHNML_00050	4.89e-63	ylbG	-	-	S	-	-	-	UPF0298 protein
NHLFHNML_00051	4.19e-84	-	-	-	S	-	-	-	Methylthioribose kinase
NHLFHNML_00052	2.67e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
NHLFHNML_00053	7.39e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHLFHNML_00054	1.04e-271	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
NHLFHNML_00055	1.66e-177	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NHLFHNML_00056	2.96e-243	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
NHLFHNML_00057	3.06e-282	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
NHLFHNML_00058	3.32e-119	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
NHLFHNML_00059	7.12e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
NHLFHNML_00060	4.09e-98	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NHLFHNML_00061	5.16e-120	ylbP	-	-	K	-	-	-	n-acetyltransferase
NHLFHNML_00062	3.84e-184	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHLFHNML_00064	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NHLFHNML_00065	4.81e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
NHLFHNML_00066	1.48e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHLFHNML_00067	2.26e-62	ftsL	-	-	D	-	-	-	cell division protein FtsL
NHLFHNML_00068	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
NHLFHNML_00070	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
NHLFHNML_00071	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHLFHNML_00072	3.53e-310	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHLFHNML_00073	2.84e-217	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHLFHNML_00074	2.77e-306	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHLFHNML_00075	1.47e-246	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NHLFHNML_00076	4.2e-165	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHLFHNML_00078	4.62e-292	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHLFHNML_00079	3.4e-240	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHLFHNML_00080	3.43e-204	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NHLFHNML_00081	8.95e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHLFHNML_00082	1.05e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHLFHNML_00083	5.13e-61	ylmC	-	-	S	-	-	-	sporulation protein
NHLFHNML_00084	2.85e-184	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
NHLFHNML_00085	2.77e-151	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHLFHNML_00086	1.13e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHLFHNML_00087	7.03e-58	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
NHLFHNML_00088	3.38e-173	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
NHLFHNML_00089	1.53e-95	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
NHLFHNML_00090	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHLFHNML_00091	1.4e-140	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
NHLFHNML_00092	3.71e-95	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHLFHNML_00093	1.94e-217	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
NHLFHNML_00094	1.55e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHLFHNML_00095	5.35e-288	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
NHLFHNML_00096	4.18e-207	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
NHLFHNML_00097	6.03e-307	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHLFHNML_00098	2.25e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NHLFHNML_00099	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
NHLFHNML_00100	4.28e-179	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHLFHNML_00101	2.73e-211	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHLFHNML_00102	2.36e-157	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHLFHNML_00103	1.64e-138	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHLFHNML_00104	1.54e-145	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
NHLFHNML_00106	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NHLFHNML_00107	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
NHLFHNML_00108	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
NHLFHNML_00109	1.15e-52	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
NHLFHNML_00110	9.15e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
NHLFHNML_00111	2.67e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHLFHNML_00112	3.81e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHLFHNML_00113	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHLFHNML_00114	1.43e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHLFHNML_00115	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHLFHNML_00116	5.6e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
NHLFHNML_00117	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NHLFHNML_00118	2.01e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHLFHNML_00119	2.6e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
NHLFHNML_00120	4.09e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
NHLFHNML_00121	1.81e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_00122	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
NHLFHNML_00123	2.67e-191	yitS	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_00124	1.51e-155	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NHLFHNML_00125	1.55e-195	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
NHLFHNML_00126	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHLFHNML_00127	1.53e-127	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NHLFHNML_00128	2.9e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHLFHNML_00129	3.45e-214	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
NHLFHNML_00130	2.35e-161	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
NHLFHNML_00131	1.35e-42	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHLFHNML_00132	1.55e-177	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHLFHNML_00133	1.67e-14	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
NHLFHNML_00134	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
NHLFHNML_00135	3.38e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHLFHNML_00136	5.45e-68	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHLFHNML_00137	2.4e-312	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHLFHNML_00138	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
NHLFHNML_00139	1.11e-45	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
NHLFHNML_00140	5.04e-90	-	-	-	S	-	-	-	YlqD protein
NHLFHNML_00141	4.94e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHLFHNML_00142	2.12e-167	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
NHLFHNML_00143	0.0	-	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
NHLFHNML_00144	1.35e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHLFHNML_00145	1.76e-09	-	-	-	L	ko:K07491	-	ko00000	Transposase
NHLFHNML_00146	6.89e-154	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
NHLFHNML_00147	6.63e-76	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
NHLFHNML_00148	1.62e-195	-	-	-	E	-	-	-	aminopeptidase
NHLFHNML_00149	3.3e-148	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
NHLFHNML_00150	1.03e-66	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_00151	3.42e-227	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
NHLFHNML_00152	2.95e-262	aldHT_2	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
NHLFHNML_00154	1.86e-93	-	4.1.2.52	-	G	ko:K02510	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
NHLFHNML_00156	4.61e-147	-	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	amidotransferase, A subunit
NHLFHNML_00157	3.71e-110	MA20_20600	1.14.17.3	-	CO	ko:K00504	-	ko00000,ko01000	amine dehydrogenase activity
NHLFHNML_00158	2.69e-11	-	-	-	-	-	-	-	-
NHLFHNML_00159	2.39e-132	sipS	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHLFHNML_00160	3.3e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHLFHNML_00162	1.54e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHLFHNML_00164	6.44e-94	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	FlhB HrpN YscU SpaS Family
NHLFHNML_00165	5.15e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NHLFHNML_00166	3.09e-215	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NHLFHNML_00167	2.49e-215	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
NHLFHNML_00168	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHLFHNML_00169	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHLFHNML_00170	1.53e-213	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
NHLFHNML_00171	2.12e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NHLFHNML_00172	1.13e-295	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NHLFHNML_00173	2.27e-174	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHLFHNML_00174	2.38e-86	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NHLFHNML_00175	5.12e-96	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
NHLFHNML_00176	2.85e-51	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
NHLFHNML_00177	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
NHLFHNML_00178	1.32e-227	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHLFHNML_00179	1.93e-102	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
NHLFHNML_00180	1.14e-310	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NHLFHNML_00181	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
NHLFHNML_00183	1.32e-264	-	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein FliK
NHLFHNML_00184	1.05e-93	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
NHLFHNML_00185	2.96e-174	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
NHLFHNML_00186	1.26e-37	flbD	-	-	N	ko:K02385	-	ko00000,ko02035	protein, possibly involved in motility
NHLFHNML_00187	9.32e-92	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
NHLFHNML_00188	7.63e-224	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHLFHNML_00189	1.29e-260	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NHLFHNML_00190	1.05e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
NHLFHNML_00191	1.07e-133	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
NHLFHNML_00192	1.47e-145	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
NHLFHNML_00193	8.01e-54	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
NHLFHNML_00194	2.52e-167	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
NHLFHNML_00195	1.39e-238	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHLFHNML_00196	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHLFHNML_00197	5.58e-222	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
NHLFHNML_00198	2.84e-123	-	-	-	-	-	-	-	-
NHLFHNML_00199	4.48e-206	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NHLFHNML_00200	2.06e-136	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NHLFHNML_00201	4.45e-109	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NHLFHNML_00202	7.05e-171	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHLFHNML_00203	1.99e-05	ylxL	-	-	-	-	-	-	-
NHLFHNML_00204	2.3e-170	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
NHLFHNML_00205	8.35e-199	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHLFHNML_00206	3.37e-160	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
NHLFHNML_00207	3.08e-115	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHLFHNML_00208	1.76e-186	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHLFHNML_00209	3.35e-175	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
NHLFHNML_00210	9.16e-264	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NHLFHNML_00211	1.81e-292	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
NHLFHNML_00212	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHLFHNML_00213	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHLFHNML_00214	1.1e-103	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
NHLFHNML_00215	9.27e-251	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
NHLFHNML_00216	3.35e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
NHLFHNML_00217	4.13e-62	ylxQ	-	-	J	-	-	-	ribosomal protein
NHLFHNML_00218	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHLFHNML_00219	2.96e-55	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
NHLFHNML_00220	2.49e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHLFHNML_00221	2.37e-218	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHLFHNML_00222	1.95e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
NHLFHNML_00223	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHLFHNML_00224	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHLFHNML_00225	1.78e-240	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
NHLFHNML_00226	4.85e-279	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
NHLFHNML_00227	1.52e-48	ymxH	-	-	S	-	-	-	YlmC YmxH family
NHLFHNML_00228	9.09e-203	spoVFA	-	-	E	ko:K06410	-	ko00000	subunit a
NHLFHNML_00229	7.62e-138	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NHLFHNML_00230	1.03e-243	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHLFHNML_00231	5.08e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NHLFHNML_00232	6.14e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHLFHNML_00233	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHLFHNML_00234	3.79e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
NHLFHNML_00235	1.37e-06	-	-	-	S	-	-	-	YlzJ-like protein
NHLFHNML_00236	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NHLFHNML_00237	3.39e-165	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_00238	6.05e-290	albE	-	-	S	-	-	-	Peptidase M16
NHLFHNML_00239	4.11e-311	ymfH	-	-	S	-	-	-	zinc protease
NHLFHNML_00240	2.17e-152	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_00241	1.34e-51	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
NHLFHNML_00242	5.43e-180	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
NHLFHNML_00243	4.82e-180	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
NHLFHNML_00244	2.85e-128	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHLFHNML_00245	9.93e-285	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
NHLFHNML_00246	0.0	deaD	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHLFHNML_00247	3.46e-242	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHLFHNML_00248	1.92e-238	-	-	-	L	-	-	-	Calcineurin-like phosphoesterase superfamily domain
NHLFHNML_00249	0.0	-	-	-	L	-	-	-	AAA domain
NHLFHNML_00250	8.1e-10	-	-	-	-	-	-	-	-
NHLFHNML_00251	7.39e-147	-	-	-	L	-	-	-	DNA recombination
NHLFHNML_00252	3.81e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
NHLFHNML_00253	1.76e-190	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
NHLFHNML_00254	7.82e-51	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
NHLFHNML_00255	1.03e-195	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
NHLFHNML_00256	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NHLFHNML_00257	3.04e-86	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
NHLFHNML_00258	1.13e-133	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
NHLFHNML_00259	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHLFHNML_00260	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHLFHNML_00261	2.46e-172	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
NHLFHNML_00262	7e-215	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHLFHNML_00263	1.24e-47	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NHLFHNML_00264	5.03e-232	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHLFHNML_00265	1.66e-219	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
NHLFHNML_00266	4.83e-312	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NHLFHNML_00267	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
NHLFHNML_00268	2.15e-284	-	-	-	C	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	FAD binding domain
NHLFHNML_00269	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
NHLFHNML_00270	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
NHLFHNML_00271	0.0	glcB	2.3.3.9	-	C	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NHLFHNML_00272	1.18e-178	-	-	-	Q	-	-	-	Domain of unknown function (DUF2437)
NHLFHNML_00273	1.97e-174	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
NHLFHNML_00274	2.21e-64	-	-	-	-	-	-	-	-
NHLFHNML_00275	2.59e-119	-	-	-	FG	-	-	-	Domain of unknown function (DUF4269)
NHLFHNML_00277	1.48e-271	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHLFHNML_00279	3.58e-282	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
NHLFHNML_00280	8.11e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHLFHNML_00282	1.62e-148	yneB	-	-	L	-	-	-	resolvase
NHLFHNML_00283	2.51e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
NHLFHNML_00284	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHLFHNML_00285	5.21e-93	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
NHLFHNML_00286	8.21e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
NHLFHNML_00287	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NHLFHNML_00288	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NHLFHNML_00289	2.41e-106	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
NHLFHNML_00290	1.22e-19	-	-	-	-	-	-	-	-
NHLFHNML_00292	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHLFHNML_00294	2.3e-06	-	-	-	S	-	-	-	Fur-regulated basic protein B
NHLFHNML_00295	3.93e-17	sspN	-	-	S	ko:K06431	-	ko00000	Small acid-soluble spore protein N family
NHLFHNML_00296	1.95e-175	-	-	-	P	ko:K07245	-	ko00000,ko02000	Copper resistance protein D
NHLFHNML_00297	0.0	spoVK_1	-	-	O	-	-	-	stage V sporulation protein K
NHLFHNML_00298	2.92e-98	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
NHLFHNML_00299	1.14e-194	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHLFHNML_00300	4.8e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
NHLFHNML_00301	5.83e-230	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHLFHNML_00302	9.32e-189	-	-	-	I	-	-	-	Hydrolase
NHLFHNML_00303	3.74e-303	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
NHLFHNML_00304	7.35e-31	-	-	-	-	-	-	-	-
NHLFHNML_00305	2.41e-42	-	-	-	S	-	-	-	YppG-like protein
NHLFHNML_00306	3.03e-91	hspX	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
NHLFHNML_00307	7.88e-215	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
NHLFHNML_00308	4.7e-202	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
NHLFHNML_00310	7.87e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
NHLFHNML_00311	6.64e-114	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHLFHNML_00312	8.19e-267	-	-	-	I	ko:K01066	-	ko00000,ko01000	COG0657 Esterase lipase
NHLFHNML_00313	1.13e-57	-	-	-	S	-	-	-	DNA alkylation repair protein
NHLFHNML_00314	7.16e-236	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NHLFHNML_00315	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHLFHNML_00316	2.33e-142	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
NHLFHNML_00317	1.8e-66	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
NHLFHNML_00318	4.7e-57	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
NHLFHNML_00319	3.51e-53	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
NHLFHNML_00320	2.5e-313	agcS	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
NHLFHNML_00321	1.69e-297	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHLFHNML_00322	5.27e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHLFHNML_00323	7.73e-99	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
NHLFHNML_00324	6.34e-154	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHLFHNML_00325	9.26e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NHLFHNML_00326	3.83e-132	-	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
NHLFHNML_00327	7.45e-239	-	-	-	T	-	-	-	Histidine kinase
NHLFHNML_00328	1.93e-146	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NHLFHNML_00329	5.97e-158	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NHLFHNML_00330	1.08e-212	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
NHLFHNML_00332	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHLFHNML_00333	5.12e-96	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
NHLFHNML_00335	2.16e-150	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
NHLFHNML_00336	1.29e-233	-	-	-	Q	-	-	-	O-methyltransferase
NHLFHNML_00338	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NHLFHNML_00339	4.1e-251	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NHLFHNML_00340	9.15e-45	yozC	-	-	-	-	-	-	-
NHLFHNML_00341	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHLFHNML_00342	4.18e-198	yvgN	-	-	S	-	-	-	reductase
NHLFHNML_00343	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
NHLFHNML_00344	7.34e-72	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
NHLFHNML_00345	4.46e-118	yocC	-	-	-	-	-	-	-
NHLFHNML_00346	2.08e-132	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_00347	2.96e-212	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
NHLFHNML_00348	1.15e-160	bshB2	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
NHLFHNML_00349	1.15e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
NHLFHNML_00350	3.8e-145	mucD	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHLFHNML_00351	2.16e-89	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
NHLFHNML_00353	1.35e-268	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
NHLFHNML_00354	9.9e-205	-	-	-	S	-	-	-	membrane
NHLFHNML_00356	9e-132	-	-	-	S	-	-	-	recombinase activity
NHLFHNML_00357	1.57e-32	-	-	-	-	-	-	-	-
NHLFHNML_00358	1.28e-54	-	-	-	E	-	-	-	IrrE N-terminal-like domain
NHLFHNML_00359	3.82e-64	-	-	-	KLT	-	-	-	serine threonine protein kinase
NHLFHNML_00360	2.36e-17	-	-	-	-	-	-	-	-
NHLFHNML_00361	4.83e-46	-	-	-	K	-	-	-	sequence-specific DNA binding
NHLFHNML_00363	5.71e-79	-	-	-	-	-	-	-	-
NHLFHNML_00369	1.5e-53	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
NHLFHNML_00373	1.33e-47	-	-	-	S	-	-	-	HNH endonuclease
NHLFHNML_00374	4.73e-73	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHLFHNML_00377	1.79e-52	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHLFHNML_00378	7.13e-52	-	-	-	K	-	-	-	BRO family, N-terminal domain
NHLFHNML_00379	3.98e-19	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
NHLFHNML_00382	2.08e-36	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NHLFHNML_00384	1.76e-63	-	-	-	S	-	-	-	NYN domain
NHLFHNML_00385	3.56e-05	-	-	-	S	-	-	-	Collagen triple helix repeat (20 copies)
NHLFHNML_00386	1.05e-95	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
NHLFHNML_00387	7.62e-234	-	-	-	S	-	-	-	Terminase-like family
NHLFHNML_00388	1.04e-179	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
NHLFHNML_00389	3.71e-65	-	-	-	S	-	-	-	Phage Mu protein F like protein
NHLFHNML_00391	2.58e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
NHLFHNML_00392	1.5e-50	-	-	-	-	-	-	-	-
NHLFHNML_00393	1.15e-174	-	-	-	S	-	-	-	Phage major capsid protein E
NHLFHNML_00397	2.65e-35	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
NHLFHNML_00399	1.57e-49	-	-	-	N	-	-	-	domain, Protein
NHLFHNML_00400	1.06e-23	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
NHLFHNML_00401	2.06e-97	-	-	-	D	-	-	-	Phage-related minor tail protein
NHLFHNML_00406	4.2e-152	-	-	-	S	-	-	-	outer membrane
NHLFHNML_00407	7.04e-16	-	-	-	-	-	-	-	-
NHLFHNML_00408	2.53e-34	xhlA	-	-	S	-	-	-	Haemolysin XhlA
NHLFHNML_00409	2.28e-32	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
NHLFHNML_00410	4.68e-91	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NHLFHNML_00413	2.41e-60	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NHLFHNML_00414	1.95e-31	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
NHLFHNML_00415	1.34e-60	-	-	-	MV	-	-	-	Ami_2
NHLFHNML_00417	2.48e-76	-	-	-	-	-	-	-	-
NHLFHNML_00418	7.36e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
NHLFHNML_00419	1.12e-41	-	-	-	-	-	-	-	-
NHLFHNML_00421	8.4e-88	-	-	-	L	-	-	-	Metallo-beta-lactamase superfamily
NHLFHNML_00423	2.26e-76	yqiX	-	-	S	-	-	-	YolD-like protein
NHLFHNML_00425	2.68e-20	-	-	-	-	-	-	-	-
NHLFHNML_00427	7.78e-81	-	-	-	V	-	-	-	HNH endonuclease
NHLFHNML_00428	2.18e-157	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHLFHNML_00429	3.84e-231	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00430	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_00431	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NHLFHNML_00432	1.3e-218	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHLFHNML_00433	2.7e-145	ydgI	-	-	C	-	-	-	nitroreductase
NHLFHNML_00434	7.32e-79	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_00435	8.24e-144	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NHLFHNML_00436	4.77e-12	-	-	-	-	-	-	-	-
NHLFHNML_00437	7.95e-172	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
NHLFHNML_00438	5.06e-165	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
NHLFHNML_00439	4.64e-75	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
NHLFHNML_00440	6.8e-227	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
NHLFHNML_00441	1.98e-175	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
NHLFHNML_00442	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_00443	1.87e-220	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00444	1.03e-205	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00445	5.44e-174	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_00446	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NHLFHNML_00447	4.68e-158	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
NHLFHNML_00448	1.46e-117	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_00449	6.11e-27	-	-	-	-	-	-	-	-
NHLFHNML_00450	2.12e-27	tnpB	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHLFHNML_00452	5e-100	-	-	-	-	-	-	-	-
NHLFHNML_00453	1.77e-94	-	5.3.1.1	-	J	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Triosephosphate isomerase
NHLFHNML_00454	2.04e-63	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
NHLFHNML_00455	9.4e-67	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
NHLFHNML_00456	7.55e-153	-	-	-	G	-	-	-	Dak1 domain
NHLFHNML_00457	4.23e-95	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
NHLFHNML_00458	4.61e-190	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
NHLFHNML_00459	3.1e-45	-	-	-	G	-	-	-	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_00460	2.21e-63	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHLFHNML_00461	2.5e-168	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NHLFHNML_00462	1.1e-77	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NHLFHNML_00463	0.0	gltD	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NHLFHNML_00464	7.46e-297	preA	1.3.1.1	-	CF	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	dihydroorotate dehydrogenase
NHLFHNML_00465	0.0	hydA	3.5.2.2	-	F	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Amidohydrolase family
NHLFHNML_00466	3.91e-09	-	-	-	-	-	-	-	-
NHLFHNML_00467	5.04e-297	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NHLFHNML_00468	0.0	-	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHLFHNML_00469	2.49e-80	-	-	-	F	-	-	-	PFAM AIG2 family protein
NHLFHNML_00470	6.05e-47	-	-	-	S	-	-	-	Integral membrane protein
NHLFHNML_00471	2.22e-280	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NHLFHNML_00472	0.0	-	-	-	S	-	-	-	Hypothetical glycosyl hydrolase 6
NHLFHNML_00473	1.19e-282	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
NHLFHNML_00474	1.89e-162	-	-	-	G	-	-	-	ABC transporter permease
NHLFHNML_00475	4.59e-188	-	-	-	G	-	-	-	ABC-type polysaccharide transport system, permease component
NHLFHNML_00476	0.0	-	-	-	G	-	-	-	beta-galactosidase
NHLFHNML_00477	3.03e-296	-	-	-	S	-	-	-	Hypothetical glycosyl hydrolase 6
NHLFHNML_00478	4.8e-137	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	3-hydroxyisobutyrate dehydrogenase
NHLFHNML_00481	4.36e-227	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLFHNML_00482	0.0	-	-	-	T	-	-	-	Domain present in phytochromes and cGMP-specific phosphodiesterases.
NHLFHNML_00483	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_00484	8.05e-196	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NHLFHNML_00485	6.03e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
NHLFHNML_00486	7.53e-94	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
NHLFHNML_00487	2.49e-181	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
NHLFHNML_00488	6.06e-156	epsB	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
NHLFHNML_00489	2.53e-149	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
NHLFHNML_00490	8.22e-217	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NHLFHNML_00491	2.45e-103	-	-	-	S	-	-	-	Tetratrico peptide repeat
NHLFHNML_00492	9.4e-105	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
NHLFHNML_00493	3.67e-119	-	-	-	G	-	-	-	Transmembrane secretion effector
NHLFHNML_00494	5.07e-281	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NHLFHNML_00495	4.06e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
NHLFHNML_00496	5.45e-207	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NHLFHNML_00497	5.58e-59	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
NHLFHNML_00498	7.3e-287	-	-	-	-	-	-	-	-
NHLFHNML_00499	2.08e-305	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHLFHNML_00500	3.63e-289	lytE	-	-	M	-	-	-	NlpC/P60 family
NHLFHNML_00502	2.58e-20	-	-	-	Q	-	-	-	N-acetyltransferase
NHLFHNML_00503	2.17e-102	yisT	-	-	S	-	-	-	DinB family
NHLFHNML_00504	2.48e-118	-	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHLFHNML_00505	0.0	pip	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
NHLFHNML_00506	1.55e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHLFHNML_00507	5.4e-174	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
NHLFHNML_00508	4.67e-139	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHLFHNML_00509	1.45e-238	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
NHLFHNML_00510	1.81e-252	-	-	-	E	-	-	-	Spore germination protein
NHLFHNML_00511	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
NHLFHNML_00512	1.05e-77	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
NHLFHNML_00513	1.04e-176	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
NHLFHNML_00514	6.51e-177	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
NHLFHNML_00515	1.9e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
NHLFHNML_00516	1.68e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
NHLFHNML_00517	7.63e-59	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
NHLFHNML_00518	7.24e-69	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
NHLFHNML_00519	1.35e-168	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
NHLFHNML_00520	4.2e-241	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
NHLFHNML_00521	1.92e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHLFHNML_00522	1.66e-21	ywmB	-	-	S	-	-	-	TATA-box binding
NHLFHNML_00523	2.09e-81	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
NHLFHNML_00524	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHLFHNML_00525	3.25e-193	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHLFHNML_00526	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHLFHNML_00527	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHLFHNML_00528	2.37e-47	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHLFHNML_00529	2.78e-28	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHLFHNML_00530	3.41e-170	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
NHLFHNML_00531	1.25e-10	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase I chain
NHLFHNML_00532	4.29e-40	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
NHLFHNML_00533	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NHLFHNML_00534	2.13e-115	panZ	-	-	K	-	-	-	-acetyltransferase
NHLFHNML_00535	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHLFHNML_00536	1.99e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHLFHNML_00537	1.18e-117	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
NHLFHNML_00538	3.9e-105	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
NHLFHNML_00539	2.87e-213	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemotaxis
NHLFHNML_00540	1.61e-92	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHLFHNML_00541	1.61e-119	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NHLFHNML_00542	1.77e-191	csbX	-	-	EGP	-	-	-	Major facilitator superfamily
NHLFHNML_00543	1.77e-124	-	5.3.1.14, 5.3.1.5	-	M	ko:K01805,ko:K01820	ko00040,ko00051,ko01100,ko01120,map00040,map00051,map01100,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
NHLFHNML_00544	7.42e-55	-	-	-	K	-	-	-	SIS domain
NHLFHNML_00545	1.88e-85	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHLFHNML_00546	4.54e-77	-	-	-	S	-	-	-	Regulator of ribonuclease activity B
NHLFHNML_00547	1.3e-232	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHLFHNML_00548	1.36e-96	ywlB	1.20.4.1, 2.3.1.1	-	E	ko:K00537,ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetyltransferase family. ArgA subfamily
NHLFHNML_00549	7.81e-148	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
NHLFHNML_00550	4.19e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHLFHNML_00551	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHLFHNML_00552	0.0	cdr	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHLFHNML_00553	4.85e-97	-	-	-	-	-	-	-	-
NHLFHNML_00554	1.27e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
NHLFHNML_00555	2.08e-54	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
NHLFHNML_00556	1.2e-299	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHLFHNML_00557	3.14e-228	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
NHLFHNML_00558	3.54e-279	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHLFHNML_00559	8.05e-149	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHLFHNML_00560	1.11e-204	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
NHLFHNML_00561	3.65e-78	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
NHLFHNML_00562	6.4e-113	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
NHLFHNML_00563	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHLFHNML_00564	3.1e-91	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHLFHNML_00565	4.32e-140	kstR2_2	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00566	2.72e-261	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
NHLFHNML_00567	6.82e-192	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
NHLFHNML_00568	1.36e-268	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
NHLFHNML_00569	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
NHLFHNML_00570	2.94e-281	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NHLFHNML_00571	6.53e-97	-	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
NHLFHNML_00572	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
NHLFHNML_00573	1.89e-100	ywiB	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_00574	2.02e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
NHLFHNML_00575	8.83e-205	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NHLFHNML_00576	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHLFHNML_00577	1.15e-199	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_00578	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
NHLFHNML_00579	3.38e-128	ywhD	-	-	S	-	-	-	YwhD family
NHLFHNML_00580	1.39e-257	-	-	-	F	-	-	-	S-adenosylhomocysteine deaminase activity
NHLFHNML_00581	1.97e-159	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
NHLFHNML_00582	6.92e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
NHLFHNML_00583	4.6e-56	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
NHLFHNML_00585	1.3e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
NHLFHNML_00586	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
NHLFHNML_00587	9.03e-264	gltP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHLFHNML_00588	7.65e-185	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NHLFHNML_00589	4.3e-231	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
NHLFHNML_00590	4.29e-180	-	5.3.3.18	-	I	ko:K15866	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
NHLFHNML_00591	2.61e-184	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
NHLFHNML_00592	5.82e-180	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHLFHNML_00593	3.16e-64	-	-	-	-	-	-	-	-
NHLFHNML_00594	3.05e-245	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
NHLFHNML_00595	6.98e-210	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_00596	1.46e-207	natA1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_00597	9.31e-84	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NHLFHNML_00598	7.33e-163	-	-	-	-	-	-	-	-
NHLFHNML_00599	6.58e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
NHLFHNML_00600	5.01e-106	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NHLFHNML_00601	4.91e-78	ywdK	-	-	S	-	-	-	small membrane protein
NHLFHNML_00602	1.58e-140	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHLFHNML_00603	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHLFHNML_00604	1.79e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5327)
NHLFHNML_00605	1.24e-170	polC1	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
NHLFHNML_00606	8.8e-214	-	-	-	T	ko:K07182	-	ko00000	Putative nucleotidyltransferase substrate binding domain
NHLFHNML_00607	7.97e-294	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
NHLFHNML_00608	4.03e-223	-	-	-	S	ko:K07120	-	ko00000	Pfam:AmoA
NHLFHNML_00609	6.67e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHLFHNML_00610	2.54e-297	-	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_00611	1.29e-190	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NHLFHNML_00612	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
NHLFHNML_00613	8.36e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
NHLFHNML_00614	1.65e-159	-	-	-	E	-	-	-	AzlC protein
NHLFHNML_00615	8.99e-31	gntR9	-	-	K	-	-	-	Alanine-glyoxylate amino-transferase
NHLFHNML_00616	1.51e-38	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
NHLFHNML_00617	3.8e-310	-	-	-	S	-	-	-	dienelactone hydrolase
NHLFHNML_00618	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
NHLFHNML_00619	6.26e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
NHLFHNML_00620	1.37e-98	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_00621	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHLFHNML_00622	1.39e-101	bdbA	-	-	CO	-	-	-	Thioredoxin
NHLFHNML_00623	2.52e-93	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
NHLFHNML_00624	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
NHLFHNML_00626	3.41e-108	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
NHLFHNML_00627	1.89e-240	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
NHLFHNML_00628	2.19e-166	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NHLFHNML_00629	4.31e-312	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
NHLFHNML_00630	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHLFHNML_00631	8.09e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
NHLFHNML_00632	4.66e-56	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
NHLFHNML_00633	3.47e-71	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
NHLFHNML_00634	2.04e-128	-	-	-	S	-	-	-	UPF0302 domain
NHLFHNML_00635	9.65e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NHLFHNML_00636	3.27e-204	XK27_03890	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHLFHNML_00637	1.14e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHLFHNML_00638	1.8e-221	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NHLFHNML_00640	8.04e-187	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NHLFHNML_00641	0.0	dapE	-	-	E	-	-	-	Peptidase dimerisation domain
NHLFHNML_00642	2.9e-275	-	-	-	S	-	-	-	Acetyltransferase
NHLFHNML_00643	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NHLFHNML_00644	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHLFHNML_00645	1.31e-269	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHLFHNML_00646	1.43e-123	-	-	-	S	-	-	-	DinB superfamily
NHLFHNML_00647	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NHLFHNML_00648	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NHLFHNML_00649	2.87e-217	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
NHLFHNML_00650	1.29e-140	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHLFHNML_00651	2.38e-141	yrbG	-	-	S	-	-	-	membrane
NHLFHNML_00652	2.42e-209	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHLFHNML_00654	5.37e-24	-	-	-	-	-	-	-	-
NHLFHNML_00655	9.67e-175	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
NHLFHNML_00656	2.18e-217	-	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
NHLFHNML_00657	8.76e-131	-	-	-	K	-	-	-	GrpB protein
NHLFHNML_00658	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHLFHNML_00659	1.65e-97	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
NHLFHNML_00660	6.43e-146	-	-	-	-	-	-	-	-
NHLFHNML_00661	2.64e-151	-	-	-	-	-	-	-	-
NHLFHNML_00662	7.86e-42	-	-	-	-	-	-	-	-
NHLFHNML_00663	1.34e-86	-	-	-	-	-	-	-	-
NHLFHNML_00664	3.09e-88	-	-	-	-	-	-	-	-
NHLFHNML_00665	3.04e-176	-	-	-	S	-	-	-	GNAT acetyltransferase
NHLFHNML_00666	5.16e-252	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHLFHNML_00668	0.0	-	-	-	T	-	-	-	Histidine kinase
NHLFHNML_00670	0.0	-	-	-	-	-	-	-	-
NHLFHNML_00671	7.92e-142	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_00672	0.0	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	Sodium:sulfate symporter transmembrane region
NHLFHNML_00673	4.94e-163	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
NHLFHNML_00674	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NHLFHNML_00675	3.05e-146	M1-740	-	-	I	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHLFHNML_00676	2.24e-211	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NHLFHNML_00677	7.81e-78	-	-	-	S	-	-	-	CHY zinc finger
NHLFHNML_00678	1.03e-286	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
NHLFHNML_00681	3.04e-54	sdpI	-	-	S	-	-	-	integral membrane protein
NHLFHNML_00682	2.9e-276	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NHLFHNML_00683	1.37e-124	-	-	-	S	ko:K09962	-	ko00000	protein conserved in bacteria
NHLFHNML_00684	8.22e-173	ubiE	-	-	Q	-	-	-	Methyltransferase type 11
NHLFHNML_00686	9.16e-301	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHLFHNML_00687	2.2e-60	phhB	3.5.4.33, 4.2.1.96	-	H	ko:K01724,ko:K11991	ko00790,map00790	ko00000,ko00001,ko01000,ko03016,ko04147	pterin-4-alpha-carbinolamine dehydratase
NHLFHNML_00688	1.04e-75	eaeH	-	-	M	ko:K13735	ko05100,map05100	ko00000,ko00001	LysM domain
NHLFHNML_00689	1.38e-88	-	-	-	S	-	-	-	YtkA-like
NHLFHNML_00690	0.0	-	-	-	T	-	-	-	Histidine kinase
NHLFHNML_00691	9.73e-155	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_00692	5.23e-231	-	-	-	S	-	-	-	amine dehydrogenase activity
NHLFHNML_00693	5.17e-239	-	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
NHLFHNML_00695	8.09e-44	-	-	-	-	-	-	-	-
NHLFHNML_00696	5.33e-67	-	-	-	S	-	-	-	Bacterial PH domain
NHLFHNML_00697	3.06e-40	-	-	-	-	-	-	-	-
NHLFHNML_00699	4.03e-127	M1-1017	-	-	S	-	-	-	Protein of unknown function (DUF1129)
NHLFHNML_00700	3.5e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_00701	3.74e-134	-	-	-	S	-	-	-	DUF218 domain
NHLFHNML_00702	1.61e-190	degV	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_00703	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHLFHNML_00704	1.33e-52	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHLFHNML_00705	1.12e-288	yciC	-	-	S	-	-	-	GTPases (G3E family)
NHLFHNML_00706	4.46e-165	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
NHLFHNML_00707	1.85e-238	mhqA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NHLFHNML_00708	0.0	-	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182	ko00130,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the UbiD family
NHLFHNML_00709	8.72e-147	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NHLFHNML_00710	3.54e-167	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHLFHNML_00711	2.01e-302	atoE	-	-	I	ko:K02106	ko02020,map02020	ko00000,ko00001	Short chain fatty acid transporter
NHLFHNML_00712	1.92e-241	malR	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00713	3.96e-190	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
NHLFHNML_00714	3.68e-314	-	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
NHLFHNML_00715	1.52e-301	malE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
NHLFHNML_00716	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
NHLFHNML_00717	8.2e-306	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
NHLFHNML_00718	6.9e-282	codB	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
NHLFHNML_00719	0.0	-	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
NHLFHNML_00720	1.58e-284	lhgO	1.1.5.3	-	S	ko:K00111,ko:K15736	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
NHLFHNML_00721	1.45e-272	-	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
NHLFHNML_00722	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
NHLFHNML_00723	3.39e-151	-	-	-	K	-	-	-	COG2186 Transcriptional regulators
NHLFHNML_00724	3.47e-153	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
NHLFHNML_00725	0.0	-	-	-	S	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
NHLFHNML_00726	8.42e-235	-	-	-	S	ko:K07080	-	ko00000	NMT1-like family
NHLFHNML_00728	9.01e-197	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_00729	2.52e-243	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NHLFHNML_00730	2.43e-270	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
NHLFHNML_00731	1e-96	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_00732	4.86e-235	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
NHLFHNML_00733	2.11e-149	kdgR	-	-	K	-	-	-	FCD
NHLFHNML_00734	9.68e-251	yjmC	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
NHLFHNML_00735	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NHLFHNML_00736	4.94e-114	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_00737	2.3e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NHLFHNML_00738	2.81e-205	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
NHLFHNML_00739	2.79e-97	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
NHLFHNML_00740	3.19e-146	-	-	-	S	-	-	-	CGNR zinc finger
NHLFHNML_00742	2.42e-110	-	-	-	-	-	-	-	-
NHLFHNML_00743	4.74e-21	-	-	-	K	ko:K07729	-	ko00000,ko03000	transcriptional
NHLFHNML_00745	0.0	-	-	-	T	-	-	-	Carbon starvation protein
NHLFHNML_00746	2.58e-173	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
NHLFHNML_00747	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_00748	1.04e-135	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00749	0.0	ydfJ	-	-	S	ko:K07003	-	ko00000	MMPL family
NHLFHNML_00750	5.82e-261	-	-	-	S	-	-	-	domain protein
NHLFHNML_00751	8.4e-234	oppF3	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_00752	8.96e-226	oppD3	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_00753	2.95e-211	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_00754	7.33e-221	appB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_00755	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHLFHNML_00756	5.96e-12	-	-	-	-	-	-	-	-
NHLFHNML_00757	9.07e-169	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
NHLFHNML_00758	2.73e-25	-	-	-	-	-	-	-	-
NHLFHNML_00759	3.74e-125	-	-	-	L	ko:K07496	-	ko00000	Transposase
NHLFHNML_00760	8.71e-112	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_00762	2.23e-156	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
NHLFHNML_00763	2.69e-265	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
NHLFHNML_00764	1.06e-100	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_00765	1.4e-235	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NHLFHNML_00766	6.95e-239	tdh	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NHLFHNML_00767	1.35e-138	-	-	-	K	-	-	-	FCD domain
NHLFHNML_00768	1.73e-304	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
NHLFHNML_00769	1.65e-53	-	-	-	-	-	-	-	-
NHLFHNML_00770	1.97e-132	-	-	-	-	-	-	-	-
NHLFHNML_00771	2.55e-167	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_00772	2.1e-162	-	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	O-methyltransferase
NHLFHNML_00773	1.06e-71	-	-	-	L	-	-	-	Restriction endonuclease
NHLFHNML_00774	4.26e-89	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
NHLFHNML_00775	1.86e-256	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_00776	4.62e-170	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00777	1.36e-171	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00778	6.16e-124	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NHLFHNML_00779	6.62e-149	-	-	-	T	-	-	-	Histidine kinase
NHLFHNML_00780	2.93e-13	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NHLFHNML_00781	1.4e-236	-	-	-	S	ko:K09704	-	ko00000	Glycosyl hydrolase
NHLFHNML_00782	9.55e-313	-	2.3.1.204, 3.2.1.24	GH38	G	ko:K01191,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
NHLFHNML_00783	1.25e-231	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
NHLFHNML_00784	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
NHLFHNML_00785	8.17e-265	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NHLFHNML_00786	1.74e-110	-	-	-	-	-	-	-	-
NHLFHNML_00787	1.27e-105	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
NHLFHNML_00788	4.18e-135	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_00789	4.03e-77	-	-	-	K	-	-	-	TetR family transcriptional regulator
NHLFHNML_00790	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NHLFHNML_00791	0.0	gmuD	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NHLFHNML_00792	2.1e-63	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_00793	3.41e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHLFHNML_00794	2.5e-58	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_00795	6.99e-144	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
NHLFHNML_00796	3.46e-184	-	3.4.16.4	-	V	ko:K01286	-	ko00000,ko01000	Beta-lactamase
NHLFHNML_00797	9.96e-95	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00798	3.41e-80	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
NHLFHNML_00799	6.79e-257	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
NHLFHNML_00800	3.89e-147	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
NHLFHNML_00801	4.09e-154	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
NHLFHNML_00802	7.93e-219	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
NHLFHNML_00803	2.46e-154	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_00804	1.48e-103	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
NHLFHNML_00805	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
NHLFHNML_00806	3.55e-234	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
NHLFHNML_00807	1.08e-244	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mannonate dehydratase activity
NHLFHNML_00808	1e-69	-	-	-	-	-	-	-	-
NHLFHNML_00809	1.62e-37	-	-	-	-	-	-	-	-
NHLFHNML_00810	3.85e-71	-	-	-	-	-	-	-	-
NHLFHNML_00811	4.1e-87	-	-	-	F	-	-	-	NUDIX domain
NHLFHNML_00812	2.69e-128	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLFHNML_00813	1.2e-50	-	-	-	-	-	-	-	-
NHLFHNML_00814	7.21e-300	-	-	-	V	-	-	-	MatE
NHLFHNML_00815	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NHLFHNML_00816	7.73e-280	-	-	-	C	ko:K03300	-	ko00000	Citrate transporter
NHLFHNML_00817	1.96e-65	-	-	-	-	-	-	-	-
NHLFHNML_00818	1.65e-299	-	-	-	E	-	-	-	Acyclic terpene utilisation family protein AtuA
NHLFHNML_00819	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
NHLFHNML_00820	3.33e-133	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NHLFHNML_00821	1.2e-203	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NHLFHNML_00822	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHLFHNML_00824	6.74e-119	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
NHLFHNML_00825	7.44e-238	fruA2	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
NHLFHNML_00826	6.25e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_00827	6.13e-100	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHLFHNML_00828	3.06e-204	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NHLFHNML_00829	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
NHLFHNML_00830	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
NHLFHNML_00831	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
NHLFHNML_00832	8.79e-284	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
NHLFHNML_00833	6.3e-105	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_00834	3.89e-241	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
NHLFHNML_00835	3.86e-237	-	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NHLFHNML_00836	5.47e-203	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_00838	1.83e-315	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_00839	1.58e-210	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00840	2.45e-182	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00841	4.52e-81	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
NHLFHNML_00842	5.18e-309	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
NHLFHNML_00843	8.49e-194	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NHLFHNML_00844	1.47e-175	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
NHLFHNML_00845	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHLFHNML_00846	1.75e-230	-	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_00847	7.4e-197	iolJ	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NHLFHNML_00848	8.26e-126	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NHLFHNML_00849	2.43e-240	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NHLFHNML_00850	5.78e-215	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NHLFHNML_00851	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NHLFHNML_00852	9.59e-221	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NHLFHNML_00853	1.33e-188	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NHLFHNML_00854	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_00855	9.27e-173	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NHLFHNML_00856	1.59e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHLFHNML_00857	3.47e-129	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00858	4.16e-78	ykkC_1	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
NHLFHNML_00859	9.65e-62	ykkD_1	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
NHLFHNML_00860	2.73e-227	-	-	-	KTV	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
NHLFHNML_00861	4.15e-122	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NHLFHNML_00862	1.65e-10	-	-	-	S	-	-	-	Putative small multi-drug export protein
NHLFHNML_00864	1.28e-167	-	-	-	-	-	-	-	-
NHLFHNML_00865	0.0	melA7	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NHLFHNML_00866	3.63e-253	araH	-	-	G	ko:K10544,ko:K10547	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHLFHNML_00867	0.0	araG	3.6.3.17	-	G	ko:K10548	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NHLFHNML_00868	4.61e-251	chvE	-	-	G	ko:K10546	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHLFHNML_00869	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
NHLFHNML_00870	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
NHLFHNML_00871	5.92e-174	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NHLFHNML_00872	7.7e-275	egsA	1.1.1.261	-	C	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NHLFHNML_00873	6.56e-180	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
NHLFHNML_00874	1.21e-209	rhaR1	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_00875	3.48e-216	M1-640	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00876	5.32e-131	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NHLFHNML_00877	6.38e-196	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00878	5.07e-204	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00879	6.51e-308	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_00880	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
NHLFHNML_00881	5.94e-201	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00882	6.96e-195	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00883	7.74e-299	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_00884	0.0	yesW	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
NHLFHNML_00885	1.25e-71	-	-	-	-	-	-	-	-
NHLFHNML_00887	1.89e-162	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
NHLFHNML_00888	5.64e-152	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_00889	3.16e-296	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NHLFHNML_00890	4.05e-246	-	-	-	I	-	-	-	Acyltransferase family
NHLFHNML_00891	1.15e-198	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00892	5.85e-225	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00893	9.51e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_00894	2.58e-253	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
NHLFHNML_00895	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_00896	1.21e-267	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_00897	4.71e-199	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLFHNML_00898	6.88e-277	-	-	-	EM	-	-	-	Protein of unknown function (DUF993)
NHLFHNML_00899	5.8e-293	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_00900	1.61e-188	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_00901	8.49e-285	-	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
NHLFHNML_00902	1.87e-68	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
NHLFHNML_00903	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
NHLFHNML_00904	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
NHLFHNML_00905	4.6e-224	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_00906	0.0	-	-	-	E	-	-	-	amino acid
NHLFHNML_00907	5.34e-214	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NHLFHNML_00908	2.95e-84	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHLFHNML_00909	6.23e-179	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NHLFHNML_00910	1.8e-178	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_00911	2.85e-237	-	-	-	-	-	-	-	-
NHLFHNML_00912	1.41e-128	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
NHLFHNML_00913	1.8e-248	-	1.1.1.361	-	S	ko:K18652	-	ko00000,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_00914	1.32e-222	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLFHNML_00915	3.59e-153	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NHLFHNML_00916	2.5e-199	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NHLFHNML_00917	3.65e-224	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00918	4.85e-119	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NHLFHNML_00919	1.83e-188	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
NHLFHNML_00920	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_00921	1.58e-265	-	-	-	EGP	ko:K08162	-	ko00000,ko02000	Major Facilitator Superfamily
NHLFHNML_00922	1.05e-175	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NHLFHNML_00923	4.49e-300	ugpB	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
NHLFHNML_00924	1.36e-177	ugpE	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter permease
NHLFHNML_00925	2.71e-207	ugpA	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NHLFHNML_00926	4.27e-253	ugpC	3.6.3.20	-	P	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_00927	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
NHLFHNML_00928	1.39e-297	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHLFHNML_00929	1.85e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
NHLFHNML_00931	1.41e-241	yneE	-	-	K	-	-	-	Arabinose-binding domain of AraC transcription regulator, N-term
NHLFHNML_00932	7.03e-177	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHLFHNML_00933	1.65e-256	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
NHLFHNML_00934	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
NHLFHNML_00935	0.0	alkK	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHLFHNML_00936	1.38e-64	-	-	-	S	-	-	-	ABC-2 family transporter protein
NHLFHNML_00937	6.9e-96	-	-	-	H	-	-	-	Tellurite resistance protein TehB
NHLFHNML_00940	5e-285	-	-	-	KLT	-	-	-	Protein kinase domain
NHLFHNML_00942	6.37e-247	-	3.6.3.20	-	P	ko:K05816	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_00943	6.89e-190	-	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
NHLFHNML_00944	9.2e-210	-	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
NHLFHNML_00945	3.98e-187	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLFHNML_00946	0.0	-	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
NHLFHNML_00947	1.59e-99	ectC	4.2.1.108	-	S	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
NHLFHNML_00948	7.39e-312	ectB	2.6.1.76	-	E	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHLFHNML_00949	3.43e-114	ectA	2.3.1.178	-	K	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-2,4-diaminobutyric acid acetyltransferase
NHLFHNML_00950	6.42e-84	-	-	-	-	-	-	-	-
NHLFHNML_00951	0.0	-	-	-	EG	ko:K06295	-	ko00000	Bacillus/Clostridium GerA spore germination protein
NHLFHNML_00952	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_00953	2.98e-252	-	-	-	C	ko:K19954	-	ko00000,ko01000	alcohol dehydrogenase
NHLFHNML_00954	7.35e-221	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
NHLFHNML_00955	3.31e-284	-	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
NHLFHNML_00956	1.89e-275	adhB	1.1.1.1, 1.1.1.202	-	C	ko:K00001,ko:K00086	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NHLFHNML_00957	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
NHLFHNML_00958	1.06e-28	-	-	-	-	-	-	-	-
NHLFHNML_00959	3.23e-70	fdx5	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
NHLFHNML_00960	4.47e-99	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00961	5.26e-173	-	-	-	C	-	-	-	alcohol dehydrogenase
NHLFHNML_00962	1.35e-126	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NHLFHNML_00963	1.51e-17	-	-	-	-	-	-	-	-
NHLFHNML_00964	8.39e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
NHLFHNML_00965	2.42e-189	manA3	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Endoglucanase
NHLFHNML_00966	6.59e-278	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_00967	5.44e-207	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NHLFHNML_00968	7.03e-194	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_00969	1.29e-191	-	-	-	GK	-	-	-	ROK family
NHLFHNML_00970	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
NHLFHNML_00971	8.01e-229	purR15	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
NHLFHNML_00972	5.49e-240	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
NHLFHNML_00973	1.06e-298	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_00974	1.55e-195	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NHLFHNML_00975	0.0	-	-	-	K	-	-	-	Propionate catabolism activator
NHLFHNML_00977	3.28e-213	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NHLFHNML_00978	1.08e-303	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
NHLFHNML_00979	1.19e-232	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
NHLFHNML_00980	2.19e-188	murR	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_00981	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NHLFHNML_00982	4.59e-173	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_00983	5.31e-217	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHLFHNML_00984	5.04e-233	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
NHLFHNML_00985	8.48e-106	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_00986	4.09e-276	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
NHLFHNML_00987	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
NHLFHNML_00988	9.04e-130	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NHLFHNML_00989	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHLFHNML_00990	1.99e-216	yueF	-	-	S	-	-	-	transporter activity
NHLFHNML_00991	2.62e-111	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
NHLFHNML_00992	5.09e-124	flaR	-	-	F	-	-	-	topology modulation protein
NHLFHNML_00993	7.06e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHLFHNML_00994	5.54e-210	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
NHLFHNML_00995	9.05e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
NHLFHNML_00996	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NHLFHNML_00997	2.07e-152	-	-	-	S	ko:K07080	-	ko00000	NMT1-like family
NHLFHNML_00998	3.21e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF1850)
NHLFHNML_00999	0.0	siaT_4	-	-	S	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
NHLFHNML_01000	1.1e-108	-	2.3.1.128	-	J	ko:K03789,ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHLFHNML_01001	1.17e-125	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
NHLFHNML_01002	7.03e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
NHLFHNML_01003	4.71e-87	-	-	-	-	-	-	-	-
NHLFHNML_01004	8.49e-140	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_01005	8.11e-167	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHLFHNML_01006	2.15e-180	-	-	-	EG	-	-	-	EamA-like transporter family
NHLFHNML_01007	4.76e-146	-	-	-	Q	-	-	-	SAM-dependent methyltransferase
NHLFHNML_01008	8.67e-230	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NHLFHNML_01009	5.94e-175	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
NHLFHNML_01010	1.1e-103	-	-	-	-	-	-	-	-
NHLFHNML_01011	6.38e-108	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHLFHNML_01012	3.92e-246	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
NHLFHNML_01013	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NHLFHNML_01014	9.1e-83	-	-	-	K	ko:K21903	-	ko00000,ko03000	transcriptional
NHLFHNML_01015	1.01e-180	-	-	-	H	ko:K17882	-	ko00000,ko01000,ko01504	KNTase C-terminal domain
NHLFHNML_01016	2.61e-83	blaI	-	-	K	ko:K02171,ko:K02546	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
NHLFHNML_01017	0.0	mecR1	-	-	KTV	ko:K02172,ko:K02547	ko01501,map01501	ko00000,ko00001,ko00002,ko01002,ko01504	BlaR1 peptidase M56
NHLFHNML_01018	7.93e-196	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
NHLFHNML_01019	4.61e-71	-	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHLFHNML_01020	9.2e-118	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_01021	3.17e-200	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_01022	3.47e-73	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
NHLFHNML_01023	8.89e-170	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_01024	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHLFHNML_01025	1.21e-288	-	-	-	EGP	-	-	-	Transmembrane secretion effector
NHLFHNML_01026	4.26e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_01027	1.07e-238	-	-	-	T	-	-	-	Histidine kinase-like ATPases
NHLFHNML_01028	5.03e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NHLFHNML_01029	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHLFHNML_01030	7.4e-180	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_01031	3.86e-282	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NHLFHNML_01032	1.43e-96	-	-	-	K	-	-	-	SpoVT / AbrB like domain
NHLFHNML_01033	2.04e-144	-	-	-	S	-	-	-	Aminoglycoside phosphotransferase
NHLFHNML_01034	2.42e-40	-	-	-	S	-	-	-	Aminoglycoside phosphotransferase
NHLFHNML_01035	3.94e-250	-	-	-	V	-	-	-	Beta-lactamase
NHLFHNML_01036	8.61e-223	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
NHLFHNML_01037	1.99e-196	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_01038	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHLFHNML_01040	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHLFHNML_01041	5.93e-281	ybbR	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_01042	6.84e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHLFHNML_01043	2.31e-155	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NHLFHNML_01044	5.59e-128	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NHLFHNML_01050	1.62e-11	-	-	-	-	-	-	-	-
NHLFHNML_01052	1.22e-09	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NHLFHNML_01053	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NHLFHNML_01054	6.66e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
NHLFHNML_01055	1.36e-243	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
NHLFHNML_01056	9.07e-13	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_01057	6.41e-28	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_01058	8.66e-96	-	-	-	-	-	-	-	-
NHLFHNML_01059	1.51e-34	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NHLFHNML_01060	6.09e-57	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
NHLFHNML_01061	8.76e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NHLFHNML_01062	1.24e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
NHLFHNML_01064	2.25e-175	-	-	-	KT	-	-	-	Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding
NHLFHNML_01066	0.0	-	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Poly A polymerase head domain
NHLFHNML_01067	2.12e-293	fabF	2.3.1.179	-	I	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHLFHNML_01068	5.1e-213	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHLFHNML_01070	5.14e-19	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	Competence protein ComG
NHLFHNML_01071	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NHLFHNML_01072	7.61e-185	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
NHLFHNML_01073	5.77e-149	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
NHLFHNML_01074	3.33e-215	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHLFHNML_01075	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
NHLFHNML_01076	2.17e-266	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
NHLFHNML_01077	3.95e-272	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
NHLFHNML_01078	4.04e-167	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
NHLFHNML_01079	1.41e-284	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHLFHNML_01080	3.5e-248	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHLFHNML_01081	5.56e-213	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
NHLFHNML_01082	1.24e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
NHLFHNML_01083	2.72e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_01084	4.2e-139	-	-	-	-	-	-	-	-
NHLFHNML_01085	4.35e-282	ywqB	-	-	S	-	-	-	zinc ion binding
NHLFHNML_01086	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHLFHNML_01088	7.05e-17	-	-	-	S	-	-	-	Intracellular proteinase inhibitor
NHLFHNML_01089	8.93e-187	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NHLFHNML_01090	4.15e-187	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NHLFHNML_01091	9.73e-55	-	-	-	-	-	-	-	-
NHLFHNML_01092	5.57e-83	ytwF	-	-	P	-	-	-	Sulfurtransferase
NHLFHNML_01093	5.62e-116	-	-	-	-	-	-	-	-
NHLFHNML_01094	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHLFHNML_01095	3.16e-196	ykgA	-	-	E	-	-	-	Amidinotransferase
NHLFHNML_01096	1.31e-63	-	-	-	S	-	-	-	IDEAL
NHLFHNML_01097	0.0	asnH	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NHLFHNML_01098	3e-88	cheW	-	-	NT	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	chemotaxis
NHLFHNML_01099	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
NHLFHNML_01100	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
NHLFHNML_01101	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	exonuclease activity
NHLFHNML_01102	7.61e-81	-	-	-	-	-	-	-	-
NHLFHNML_01103	2.78e-140	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
NHLFHNML_01104	1.5e-184	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHLFHNML_01105	1.23e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHLFHNML_01106	2.52e-205	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
NHLFHNML_01107	4.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
NHLFHNML_01108	2.34e-211	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
NHLFHNML_01109	5.83e-100	-	-	-	S	-	-	-	DinB family
NHLFHNML_01110	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NHLFHNML_01111	2.21e-166	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
NHLFHNML_01112	1.41e-264	-	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
NHLFHNML_01113	4.16e-150	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
NHLFHNML_01115	1.88e-273	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
NHLFHNML_01116	2.47e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	SpoVT / AbrB like domain
NHLFHNML_01117	1.58e-59	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
NHLFHNML_01118	5.37e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
NHLFHNML_01119	5.22e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
NHLFHNML_01120	0.0	cafA	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease, Rne Rng family
NHLFHNML_01121	3.38e-172	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
NHLFHNML_01122	6.87e-163	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
NHLFHNML_01123	1.93e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
NHLFHNML_01124	9.17e-118	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
NHLFHNML_01125	2.17e-97	-	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaC family
NHLFHNML_01126	6.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
NHLFHNML_01127	6.84e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
NHLFHNML_01128	2.21e-156	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NHLFHNML_01129	1.48e-103	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
NHLFHNML_01130	4.17e-203	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
NHLFHNML_01131	1.99e-238	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
NHLFHNML_01132	2.9e-156	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
NHLFHNML_01133	1.66e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
NHLFHNML_01134	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
NHLFHNML_01135	4.4e-247	-	-	-	-	ko:K06380	-	ko00000	-
NHLFHNML_01136	3.67e-145	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NHLFHNML_01137	6.81e-292	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
NHLFHNML_01138	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHLFHNML_01139	1.27e-37	-	-	-	-	-	-	-	-
NHLFHNML_01140	1.37e-142	-	-	-	-	-	-	-	-
NHLFHNML_01141	5.51e-239	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NHLFHNML_01142	2.7e-198	-	-	-	-	-	-	-	-
NHLFHNML_01143	7.35e-226	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
NHLFHNML_01144	2.78e-309	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
NHLFHNML_01145	1.05e-228	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
NHLFHNML_01146	3.5e-170	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
NHLFHNML_01147	8.46e-212	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NHLFHNML_01148	5.2e-186	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
NHLFHNML_01149	6.41e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NHLFHNML_01150	1.03e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
NHLFHNML_01151	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NHLFHNML_01152	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
NHLFHNML_01153	2.85e-303	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHLFHNML_01154	8.96e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHLFHNML_01155	4.97e-227	ysoA	-	-	O	-	-	-	COG0457 FOG TPR repeat
NHLFHNML_01156	4.07e-144	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHLFHNML_01157	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHLFHNML_01158	1.93e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHLFHNML_01159	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHLFHNML_01160	2.5e-235	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHLFHNML_01161	7.17e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NHLFHNML_01162	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
NHLFHNML_01163	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
NHLFHNML_01164	4.22e-90	-	-	-	-	-	-	-	-
NHLFHNML_01165	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
NHLFHNML_01166	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
NHLFHNML_01167	6.11e-122	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NHLFHNML_01168	1.15e-302	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
NHLFHNML_01169	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
NHLFHNML_01171	1.53e-14	-	-	-	-	-	-	-	-
NHLFHNML_01174	6.23e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
NHLFHNML_01175	5.31e-136	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHLFHNML_01176	1.89e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NHLFHNML_01177	1.42e-236	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
NHLFHNML_01178	3.62e-248	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
NHLFHNML_01179	3.13e-42	-	-	-	C	-	-	-	4Fe-4S binding domain
NHLFHNML_01180	5.03e-191	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
NHLFHNML_01181	3.85e-103	ysmB	-	-	K	-	-	-	transcriptional
NHLFHNML_01182	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHLFHNML_01183	2.33e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
NHLFHNML_01184	2.77e-45	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_01185	9.88e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
NHLFHNML_01186	1.2e-185	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
NHLFHNML_01187	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
NHLFHNML_01188	5.12e-145	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
NHLFHNML_01189	2.47e-293	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
NHLFHNML_01190	7.17e-99	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
NHLFHNML_01191	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHLFHNML_01192	1.37e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
NHLFHNML_01193	4.22e-219	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
NHLFHNML_01194	3.49e-172	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
NHLFHNML_01195	3.35e-170	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
NHLFHNML_01196	1.59e-131	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_01197	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHLFHNML_01198	4.19e-87	yshE	-	-	S	ko:K08989	-	ko00000	membrane
NHLFHNML_01199	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHLFHNML_01200	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
NHLFHNML_01201	8.3e-117	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
NHLFHNML_01202	4.31e-44	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHLFHNML_01203	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHLFHNML_01204	4.56e-244	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHLFHNML_01205	3.92e-164	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHLFHNML_01206	3.13e-42	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
NHLFHNML_01208	1.53e-24	-	-	-	-	-	-	-	-
NHLFHNML_01209	8.37e-257	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
NHLFHNML_01210	1.12e-85	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
NHLFHNML_01211	5.65e-72	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHLFHNML_01212	9.32e-70	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
NHLFHNML_01213	5.42e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHLFHNML_01214	3.08e-39	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
NHLFHNML_01215	2.34e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHLFHNML_01216	3.18e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
NHLFHNML_01217	2.79e-153	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_01218	1.29e-296	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHLFHNML_01219	1.47e-166	-	-	-	-	-	-	-	-
NHLFHNML_01220	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NHLFHNML_01221	1.49e-224	-	-	-	C	-	-	-	Aldo/keto reductase family
NHLFHNML_01222	5.91e-234	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_01223	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHLFHNML_01224	6.73e-208	ytxC	-	-	S	-	-	-	YtxC-like family
NHLFHNML_01225	7.83e-285	mqnC	1.21.98.1	-	H	ko:K11784	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
NHLFHNML_01226	1.66e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
NHLFHNML_01227	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
NHLFHNML_01228	4.36e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHLFHNML_01229	1.6e-85	-	-	-	-	-	-	-	-
NHLFHNML_01230	1.05e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NHLFHNML_01231	1.94e-245	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHLFHNML_01232	2.94e-128	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHLFHNML_01233	5.02e-134	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
NHLFHNML_01234	1.4e-197	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHLFHNML_01235	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHLFHNML_01236	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
NHLFHNML_01237	2.8e-170	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_01238	7.52e-85	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
NHLFHNML_01239	9.96e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
NHLFHNML_01240	3.09e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
NHLFHNML_01241	5.73e-263	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NHLFHNML_01242	4.98e-96	-	-	-	S	-	-	-	UPF0756 membrane protein
NHLFHNML_01243	4.09e-78	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
NHLFHNML_01244	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
NHLFHNML_01245	3.27e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHLFHNML_01246	1.97e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHLFHNML_01247	1.1e-196	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHLFHNML_01248	2.38e-148	lutR_1	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
NHLFHNML_01249	4.23e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
NHLFHNML_01250	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
NHLFHNML_01251	4.62e-70	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
NHLFHNML_01252	1.03e-117	ytrI	-	-	-	-	-	-	-
NHLFHNML_01253	3.08e-213	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
NHLFHNML_01254	3.35e-11	ytpI	-	-	S	-	-	-	YtpI-like protein
NHLFHNML_01255	2.37e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
NHLFHNML_01257	3.84e-162	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
NHLFHNML_01258	2.05e-255	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
NHLFHNML_01259	4.51e-84	-	-	-	-	-	-	-	-
NHLFHNML_01260	4.14e-177	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_01262	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NHLFHNML_01263	1.18e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHLFHNML_01265	1.03e-212	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
NHLFHNML_01266	2.04e-275	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHLFHNML_01267	1.33e-228	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
NHLFHNML_01268	3.92e-110	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHLFHNML_01269	1.77e-250	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NHLFHNML_01270	1.19e-97	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
NHLFHNML_01271	1.49e-154	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
NHLFHNML_01272	1.82e-126	yteJ	-	-	S	-	-	-	RDD family
NHLFHNML_01273	2.68e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
NHLFHNML_01274	1.17e-38	-	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
NHLFHNML_01275	1.78e-283	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHLFHNML_01276	1.07e-262	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NHLFHNML_01277	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHLFHNML_01278	2.54e-181	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NHLFHNML_01279	6.15e-146	yttP	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01280	7.5e-19	-	-	-	L	ko:K07496	-	ko00000	Transposase
NHLFHNML_01281	1.88e-112	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
NHLFHNML_01282	4.92e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHLFHNML_01283	3.55e-297	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHLFHNML_01284	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG0744 Membrane carboxypeptidase (penicillin-binding protein)
NHLFHNML_01285	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHLFHNML_01286	0.0	malP	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_01287	6.86e-177	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NHLFHNML_01288	6.81e-103	-	-	-	-	-	-	-	-
NHLFHNML_01290	1.96e-223	lacC	2.7.1.144	-	G	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
NHLFHNML_01291	9.72e-182	-	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
NHLFHNML_01292	1.32e-101	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHLFHNML_01293	2.76e-55	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
NHLFHNML_01294	1.44e-311	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
NHLFHNML_01295	1.08e-246	-	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
NHLFHNML_01296	5.92e-201	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
NHLFHNML_01297	7.78e-72	yyaQ	-	-	S	-	-	-	Protein conserved in bacteria
NHLFHNML_01298	1.34e-131	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
NHLFHNML_01299	7.56e-39	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NHLFHNML_01300	1.23e-39	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_01301	2.07e-175	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
NHLFHNML_01303	2.13e-26	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHLFHNML_01304	1.1e-115	-	-	-	K	-	-	-	Helix-turn-helix domain
NHLFHNML_01305	6.39e-199	rspA	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NHLFHNML_01306	1.86e-126	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NHLFHNML_01307	6.04e-71	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_01309	2.96e-312	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHLFHNML_01310	6.77e-183	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01311	4.6e-70	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NHLFHNML_01312	5.98e-83	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NHLFHNML_01313	1.2e-181	-	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_01314	1.22e-191	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_01315	1.83e-171	-	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
NHLFHNML_01316	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
NHLFHNML_01317	1.3e-209	XK27_06795	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHLFHNML_01319	0.0	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
NHLFHNML_01320	0.0	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
NHLFHNML_01321	3.1e-131	-	-	-	H	-	-	-	Flavoprotein
NHLFHNML_01322	1.82e-74	orfX1	-	-	L	-	-	-	Transposase
NHLFHNML_01323	1.77e-160	-	-	-	L	-	-	-	Integrase core domain
NHLFHNML_01324	8.87e-158	pstB13	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
NHLFHNML_01325	3.04e-159	-	-	-	S	-	-	-	ABC-2 family transporter protein
NHLFHNML_01326	3.05e-161	-	-	-	-	-	-	-	-
NHLFHNML_01327	1.75e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
NHLFHNML_01328	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NHLFHNML_01329	1.46e-80	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
NHLFHNML_01331	6.06e-224	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
NHLFHNML_01333	4.48e-231	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
NHLFHNML_01334	5.21e-197	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHLFHNML_01335	1.28e-80	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHLFHNML_01336	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NHLFHNML_01337	2.68e-205	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHLFHNML_01338	5.65e-206	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
NHLFHNML_01339	4.61e-149	-	-	-	-	-	-	-	-
NHLFHNML_01340	2.95e-41	-	-	-	-	-	-	-	-
NHLFHNML_01343	1.64e-98	-	-	-	-	-	-	-	-
NHLFHNML_01344	4.25e-85	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01345	7.46e-120	-	-	-	-	-	-	-	-
NHLFHNML_01346	0.0	-	-	-	-	-	-	-	-
NHLFHNML_01347	2.71e-71	-	-	-	-	-	-	-	-
NHLFHNML_01348	3.01e-216	-	-	-	S	-	-	-	Choline/ethanolamine kinase
NHLFHNML_01349	7.91e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_01350	4.89e-264	-	-	-	S	-	-	-	Erythromycin esterase
NHLFHNML_01351	4.24e-239	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
NHLFHNML_01352	2.68e-172	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_01353	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
NHLFHNML_01354	5.47e-239	-	-	-	E	-	-	-	Amidinotransferase
NHLFHNML_01355	1.19e-231	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_01356	1.01e-190	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_01357	3.28e-129	-	-	-	S	-	-	-	ABC-2 family transporter protein
NHLFHNML_01358	9.78e-190	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01359	1.61e-193	yxxF	-	-	EG	-	-	-	EamA-like transporter family
NHLFHNML_01360	1.24e-234	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_01361	3.17e-298	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
NHLFHNML_01362	6.28e-307	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
NHLFHNML_01363	1.26e-184	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
NHLFHNML_01364	1.18e-297	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
NHLFHNML_01365	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
NHLFHNML_01366	6.62e-163	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NHLFHNML_01368	1.06e-117	-	-	-	S	-	-	-	DinB superfamily
NHLFHNML_01369	6.15e-261	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
NHLFHNML_01370	9.31e-251	-	6.3.5.5	-	S	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	ATP-grasp domain
NHLFHNML_01371	3.12e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_01372	3.44e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
NHLFHNML_01373	1.24e-198	-	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylases
NHLFHNML_01374	1.33e-06	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
NHLFHNML_01375	7.41e-131	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NHLFHNML_01377	1.5e-196	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NHLFHNML_01378	8.15e-270	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
NHLFHNML_01379	1.07e-58	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
NHLFHNML_01380	1.99e-217	-	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHLFHNML_01381	0.0	-	-	-	GKT	-	-	-	Mga helix-turn-helix domain
NHLFHNML_01382	2.22e-82	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHLFHNML_01383	0.0	-	-	-	S	-	-	-	Chlorophyllase enzyme
NHLFHNML_01384	1.38e-171	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_01385	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
NHLFHNML_01386	7.04e-233	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
NHLFHNML_01387	4.88e-226	gerKB	-	-	E	-	-	-	Spore germination protein
NHLFHNML_01388	1.17e-116	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
NHLFHNML_01389	2.31e-58	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
NHLFHNML_01390	5e-11	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
NHLFHNML_01391	3.53e-198	-	-	-	-	-	-	-	-
NHLFHNML_01392	3.97e-226	ectD	1.14.11.55	-	Q	ko:K10674	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Phytanoyl-CoA dioxygenase (PhyH)
NHLFHNML_01393	2.8e-54	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
NHLFHNML_01394	2.13e-156	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
NHLFHNML_01395	7.82e-59	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_01396	1.52e-160	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
NHLFHNML_01397	4.83e-102	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01398	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
NHLFHNML_01399	5.99e-219	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
NHLFHNML_01400	2.99e-228	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_01401	4.15e-234	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_01402	1.24e-190	yuiI	-	-	S	ko:K07017	-	ko00000	Putative esterase
NHLFHNML_01403	2.98e-305	amaB_2	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NHLFHNML_01404	1.32e-153	-	-	-	KT	-	-	-	Forkhead associated domain
NHLFHNML_01405	1.34e-197	-	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
NHLFHNML_01406	9.85e-169	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NHLFHNML_01407	4.07e-292	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
NHLFHNML_01408	5.23e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHLFHNML_01409	2.61e-198	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
NHLFHNML_01410	8.71e-232	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHLFHNML_01411	5.43e-183	-	-	-	K	-	-	-	Helix-turn-helix domain
NHLFHNML_01412	2.78e-73	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
NHLFHNML_01413	6.63e-234	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
NHLFHNML_01414	5.89e-231	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_01415	1.66e-287	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_01416	1.53e-214	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01417	8.85e-181	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01418	1.53e-21	-	-	-	G	-	-	-	Xylose isomerase
NHLFHNML_01419	1.12e-208	-	-	-	G	-	-	-	Xylose isomerase
NHLFHNML_01420	5.49e-129	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NHLFHNML_01422	1.41e-137	-	-	-	K	ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NHLFHNML_01423	2.5e-79	-	-	-	-	-	-	-	-
NHLFHNML_01424	2.9e-31	-	-	-	-	-	-	-	-
NHLFHNML_01425	2.08e-112	-	1.8.5.2	-	S	ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	DoxX
NHLFHNML_01426	0.0	-	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHLFHNML_01427	7.99e-190	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHLFHNML_01428	2.16e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_01429	2.33e-143	yqeB	-	-	-	-	-	-	-
NHLFHNML_01430	4.36e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
NHLFHNML_01431	2.4e-118	-	-	-	V	-	-	-	(ABC) transporter
NHLFHNML_01432	5.11e-209	-	-	-	V	-	-	-	VanW like protein
NHLFHNML_01434	4.2e-158	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
NHLFHNML_01435	1.43e-224	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NHLFHNML_01436	6.25e-207	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
NHLFHNML_01437	0.0	-	-	-	-	-	-	-	-
NHLFHNML_01438	2.95e-248	dctP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHLFHNML_01439	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase
NHLFHNML_01440	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
NHLFHNML_01441	1.15e-108	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
NHLFHNML_01442	2.17e-62	-	-	-	-	-	-	-	-
NHLFHNML_01443	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NHLFHNML_01444	3.02e-06	sda	-	-	S	ko:K06371	-	ko00000	sporulation
NHLFHNML_01446	7.19e-83	yqiX	-	-	S	-	-	-	YolD-like protein
NHLFHNML_01447	6.15e-280	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NHLFHNML_01448	6.84e-277	-	-	-	GK	-	-	-	ROK family
NHLFHNML_01449	2.1e-307	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_01450	2.45e-217	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01451	9.08e-189	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01452	2.41e-236	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_01453	5.07e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_01454	3.51e-188	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
NHLFHNML_01455	1.18e-223	-	3.8.1.3	-	S	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
NHLFHNML_01456	3.39e-191	gltR3	-	-	K	-	-	-	LysR substrate binding domain
NHLFHNML_01457	1.96e-158	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NHLFHNML_01458	1.08e-275	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NHLFHNML_01459	0.0	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
NHLFHNML_01460	8.42e-142	-	-	-	K	-	-	-	Bacterial transcriptional repressor C-terminal
NHLFHNML_01461	2.09e-171	-	-	-	S	-	-	-	Methyltransferase domain
NHLFHNML_01462	2.31e-281	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHLFHNML_01463	3.89e-215	fhuD11	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NHLFHNML_01464	3.33e-221	fhuG7	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_01465	4.89e-70	isdG	1.14.99.48	-	C	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
NHLFHNML_01466	1.25e-143	isdC	-	-	M	-	-	-	NEAr Transporter domain
NHLFHNML_01467	7.83e-294	-	-	-	M	-	-	-	Cell surface protein
NHLFHNML_01468	1.27e-197	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_01469	9.72e-210	fhuB11	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_01470	7.88e-169	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_01471	5.21e-178	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
NHLFHNML_01472	3.92e-305	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NHLFHNML_01473	5.51e-204	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycine betaine ABC transporter
NHLFHNML_01474	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2254)
NHLFHNML_01475	2.78e-221	-	-	-	P	ko:K07217	-	ko00000	Catalase
NHLFHNML_01476	3.35e-214	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
NHLFHNML_01477	3.84e-281	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHLFHNML_01478	2.54e-10	-	-	-	-	-	-	-	-
NHLFHNML_01479	3.42e-181	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
NHLFHNML_01480	8.09e-139	-	-	-	Q	-	-	-	Methyltransferase domain
NHLFHNML_01481	2.55e-79	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
NHLFHNML_01482	5.11e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLFHNML_01483	6.03e-160	-	-	-	-	-	-	-	-
NHLFHNML_01484	1.61e-194	yerO	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01486	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHLFHNML_01487	8.04e-158	-	-	-	S	-	-	-	membrane
NHLFHNML_01488	2.44e-112	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NHLFHNML_01489	1.46e-206	ytlI3	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
NHLFHNML_01490	5.36e-114	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
NHLFHNML_01491	2.78e-53	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_01492	1.69e-207	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_01493	9.85e-72	-	-	-	S	-	-	-	Dinitrogenase iron-molybdenum cofactor
NHLFHNML_01494	2.46e-172	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
NHLFHNML_01495	1.07e-248	-	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
NHLFHNML_01496	5.33e-217	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_01497	3.12e-175	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHLFHNML_01498	0.0	gdhA	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NHLFHNML_01499	5.54e-212	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_01500	4.85e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
NHLFHNML_01501	1.43e-201	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
NHLFHNML_01502	5.86e-195	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHLFHNML_01503	3.18e-141	-	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NHLFHNML_01504	4.03e-215	-	-	-	K	-	-	-	WYL domain
NHLFHNML_01505	2.86e-215	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_01506	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
NHLFHNML_01507	1.11e-101	-	-	-	S	-	-	-	ASCH
NHLFHNML_01508	4.01e-100	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
NHLFHNML_01509	3.22e-69	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
NHLFHNML_01510	1.69e-232	cbrA5	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ferrichrome ABC transporter substrate-binding protein
NHLFHNML_01511	0.0	fhuB5	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_01512	6.67e-173	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NHLFHNML_01513	2.4e-166	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01514	9.37e-241	-	-	-	P	-	-	-	NMT1-like family
NHLFHNML_01516	1.55e-179	-	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NHLFHNML_01517	7.26e-185	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01518	7.16e-232	-	-	-	P	-	-	-	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NHLFHNML_01519	6.78e-225	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NHLFHNML_01520	4.28e-129	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
NHLFHNML_01521	1.15e-202	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NHLFHNML_01522	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NHLFHNML_01523	2.44e-111	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NHLFHNML_01524	1.04e-309	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NHLFHNML_01525	1.08e-289	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NHLFHNML_01526	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
NHLFHNML_01527	1.92e-113	-	-	-	S	-	-	-	OHCU decarboxylase
NHLFHNML_01528	1.19e-224	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NHLFHNML_01529	3.78e-74	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NHLFHNML_01530	0.0	-	-	-	S	-	-	-	Membrane
NHLFHNML_01531	2.29e-308	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NHLFHNML_01532	8.24e-271	-	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
NHLFHNML_01534	8.35e-176	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
NHLFHNML_01535	3.03e-63	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
NHLFHNML_01536	2e-120	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
NHLFHNML_01537	2.66e-290	-	-	-	S	-	-	-	Putative esterase
NHLFHNML_01538	7.08e-196	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
NHLFHNML_01539	1.19e-103	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
NHLFHNML_01540	2.6e-103	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
NHLFHNML_01541	1.33e-181	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NHLFHNML_01542	1.78e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_01543	6.37e-191	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHLFHNML_01544	4.92e-219	-	2.7.1.194	-	GKT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	COG3711 Transcriptional antiterminator
NHLFHNML_01545	4.17e-42	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_01546	1.64e-229	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
NHLFHNML_01547	2.58e-108	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
NHLFHNML_01548	8.19e-162	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
NHLFHNML_01549	2.12e-177	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHLFHNML_01550	4.1e-237	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_01551	1.71e-203	-	-	-	E	-	-	-	Glyoxalase-like domain
NHLFHNML_01552	4.4e-172	-	-	-	G	-	-	-	Phosphoenolpyruvate phosphomutase
NHLFHNML_01553	1.42e-131	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NHLFHNML_01554	7.93e-59	sdpR	-	-	K	-	-	-	transcriptional
NHLFHNML_01555	5.2e-198	-	-	-	K	-	-	-	LysR substrate binding domain
NHLFHNML_01556	1.97e-151	mdmC1	-	-	S	-	-	-	O-methyltransferase
NHLFHNML_01557	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
NHLFHNML_01558	1.88e-167	ycdF	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
NHLFHNML_01559	1.22e-100	-	-	-	S	-	-	-	Bacterial PH domain
NHLFHNML_01560	2.12e-23	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
NHLFHNML_01561	1.27e-59	-	-	-	S	-	-	-	LXG domain of WXG superfamily
NHLFHNML_01567	7.57e-59	-	-	-	-	-	-	-	-
NHLFHNML_01568	1.34e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
NHLFHNML_01569	1.11e-133	-	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
NHLFHNML_01570	3.81e-253	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
NHLFHNML_01571	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
NHLFHNML_01572	4.24e-232	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
NHLFHNML_01573	4.29e-255	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
NHLFHNML_01574	4.93e-233	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NHLFHNML_01577	6.3e-198	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NHLFHNML_01578	9.15e-207	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NHLFHNML_01579	1.07e-139	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
NHLFHNML_01581	3.76e-77	csaB	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
NHLFHNML_01583	1.6e-41	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
NHLFHNML_01584	6.1e-39	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
NHLFHNML_01585	2.73e-43	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
NHLFHNML_01586	3.71e-266	-	2.7.7.13	-	G	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
NHLFHNML_01587	2.77e-305	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHLFHNML_01588	1.1e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF3784)
NHLFHNML_01590	1.05e-162	-	-	-	K	-	-	-	AraC-type transcriptional regulator N-terminus
NHLFHNML_01591	2.14e-65	-	-	-	S	-	-	-	Agrobacterium tumefaciens protein Atu4866
NHLFHNML_01592	1.59e-144	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_01594	3.41e-128	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
NHLFHNML_01595	1.62e-87	ytcD	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01596	3.61e-146	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
NHLFHNML_01597	2.59e-41	-	-	-	L	ko:K07483	-	ko00000	Transposase
NHLFHNML_01600	1.69e-136	-	-	-	S	-	-	-	LXG domain of WXG superfamily
NHLFHNML_01606	0.0	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
NHLFHNML_01607	2.28e-113	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
NHLFHNML_01608	3.24e-143	-	-	-	S	-	-	-	CAAX protease self-immunity
NHLFHNML_01610	7.59e-316	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHLFHNML_01611	2.22e-61	-	-	-	-	-	-	-	-
NHLFHNML_01612	1.43e-291	celD	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHLFHNML_01613	7.7e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_01614	1.13e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NHLFHNML_01615	6.72e-266	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
NHLFHNML_01616	6.62e-196	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
NHLFHNML_01617	3.47e-210	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01619	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHLFHNML_01620	3.52e-201	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01621	1.12e-214	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NHLFHNML_01622	6.4e-233	-	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_01623	2.36e-246	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_01624	3.89e-284	-	-	-	E	-	-	-	Peptidase family M28
NHLFHNML_01625	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
NHLFHNML_01626	1.53e-287	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
NHLFHNML_01627	4.94e-288	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
NHLFHNML_01628	1.85e-115	-	-	-	-	-	-	-	-
NHLFHNML_01631	2.16e-240	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_01632	2.2e-252	fbpC	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHLFHNML_01633	0.0	sfuB	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01634	0.0	-	-	-	T	-	-	-	Histidine kinase
NHLFHNML_01635	1.68e-177	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
NHLFHNML_01636	7.75e-258	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NHLFHNML_01637	6.07e-165	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
NHLFHNML_01638	8.34e-198	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHLFHNML_01639	4.78e-46	-	-	-	-	-	-	-	-
NHLFHNML_01640	4.22e-84	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
NHLFHNML_01641	1.13e-156	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
NHLFHNML_01642	6.19e-42	-	-	-	L	-	-	-	Transposase
NHLFHNML_01643	3.65e-87	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_01644	5.42e-101	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
NHLFHNML_01645	4.21e-143	metN_1	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHLFHNML_01646	3.94e-77	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
NHLFHNML_01647	3.59e-110	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NHLFHNML_01648	2.61e-221	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_01649	2.91e-208	ytnJ	-	-	C	-	-	-	Monooxygenase
NHLFHNML_01650	1.74e-67	ytmO	-	-	C	-	-	-	Alkane 1-monooxygenase
NHLFHNML_01651	5.02e-09	ytmO	-	-	C	-	-	-	Alkane 1-monooxygenase
NHLFHNML_01652	5.97e-64	-	-	-	ET	ko:K02030,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	extracellular solute-binding
NHLFHNML_01653	2.64e-89	yxeN	-	-	E	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01654	3.59e-102	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	amino acid ABC transporter ATP-binding protein
NHLFHNML_01655	7.9e-38	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
NHLFHNML_01656	7.86e-68	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHLFHNML_01657	2.85e-187	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
NHLFHNML_01658	5.54e-81	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
NHLFHNML_01660	6.48e-200	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_01661	1.6e-305	oppF	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_01662	1.11e-126	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01663	4.01e-154	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
NHLFHNML_01664	3.35e-232	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_01665	2.7e-34	lysR1	-	-	K	-	-	-	COG0583 Transcriptional regulator
NHLFHNML_01666	1.86e-47	lysR1	-	-	K	-	-	-	COG0583 Transcriptional regulator
NHLFHNML_01667	0.000275	rapA	-	-	S	ko:K06359,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NHLFHNML_01668	1.11e-171	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NHLFHNML_01669	1.98e-201	ycnC	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01670	4.39e-211	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
NHLFHNML_01671	2.54e-77	ydeP9	-	-	K	-	-	-	HxlR-like helix-turn-helix
NHLFHNML_01672	0.0	-	-	-	F	-	-	-	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
NHLFHNML_01673	1.66e-216	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
NHLFHNML_01674	6.56e-222	-	-	-	P	ko:K07217	-	ko00000	Catalase
NHLFHNML_01675	5.2e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
NHLFHNML_01678	8.09e-260	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NHLFHNML_01679	2.35e-170	-	-	-	K	ko:K19333	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_01680	6.46e-242	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NHLFHNML_01681	2.6e-107	-	-	-	G	ko:K11689	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_01682	3.28e-271	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
NHLFHNML_01683	8.64e-177	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_01684	2.25e-118	-	-	-	S	-	-	-	DNA-binding protein with PD1-like DNA-binding motif
NHLFHNML_01685	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHLFHNML_01686	7.44e-258	-	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Thiolase, C-terminal domain
NHLFHNML_01687	3.64e-70	-	-	-	S	ko:K07068	-	ko00000	DUF35 OB-fold domain, acyl-CoA-associated
NHLFHNML_01688	1.93e-304	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
NHLFHNML_01689	2.75e-270	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
NHLFHNML_01690	3.62e-170	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_01691	1.04e-170	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NHLFHNML_01692	1.24e-103	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
NHLFHNML_01693	8.78e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
NHLFHNML_01694	2.51e-144	-	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NHLFHNML_01695	5.16e-221	-	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Bacterial fructose-1,6-bisphosphatase, glpX-encoded
NHLFHNML_01696	1.11e-87	-	-	-	-	-	-	-	-
NHLFHNML_01697	1.62e-37	-	-	-	-	-	-	-	-
NHLFHNML_01699	3.59e-173	-	-	-	G	-	-	-	ABC transporter (permease)
NHLFHNML_01700	3.19e-177	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01701	1.01e-246	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_01702	1.38e-269	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_01703	1.19e-188	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
NHLFHNML_01704	1.39e-208	-	3.2.1.180	GH88	O	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
NHLFHNML_01705	5.25e-283	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
NHLFHNML_01706	1.67e-242	-	-	-	S	-	-	-	Heparinase II/III-like protein
NHLFHNML_01707	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
NHLFHNML_01708	1.5e-101	-	-	-	S	-	-	-	yiaA/B two helix domain
NHLFHNML_01709	3.15e-85	-	-	-	GKT	-	-	-	PRD domain
NHLFHNML_01710	1.63e-22	-	-	-	G	-	-	-	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_01711	2.69e-136	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
NHLFHNML_01712	2.55e-158	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_01713	9.95e-255	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_01714	9.23e-161	-	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHLFHNML_01715	7.35e-83	-	-	-	P	-	-	-	Bacterial extracellular solute-binding protein
NHLFHNML_01716	4.09e-70	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
NHLFHNML_01718	0.0	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
NHLFHNML_01719	6.41e-126	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
NHLFHNML_01720	5.49e-48	-	-	-	L	ko:K07483	-	ko00000	Transposase
NHLFHNML_01721	1.4e-89	-	-	-	S	ko:K07149	-	ko00000	Membrane
NHLFHNML_01722	7.94e-61	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_01723	6.71e-257	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHLFHNML_01724	4.51e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
NHLFHNML_01725	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NHLFHNML_01726	3.53e-155	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NHLFHNML_01727	3.48e-164	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
NHLFHNML_01728	1.76e-189	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_01729	1.1e-235	opuBA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHLFHNML_01730	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NHLFHNML_01731	1.47e-91	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
NHLFHNML_01732	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHLFHNML_01733	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHLFHNML_01734	8.76e-75	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2200)
NHLFHNML_01735	3.11e-103	yocK	-	-	T	-	-	-	general stress protein
NHLFHNML_01736	2.57e-255	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
NHLFHNML_01737	7.36e-172	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
NHLFHNML_01738	2.45e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
NHLFHNML_01739	1.61e-191	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NHLFHNML_01740	4.87e-140	-	-	-	S	-	-	-	Golgi phosphoprotein 3 (GPP34)
NHLFHNML_01741	1.18e-47	-	-	-	K	-	-	-	COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
NHLFHNML_01742	5.69e-19	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NHLFHNML_01743	9.86e-100	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NHLFHNML_01744	2.07e-113	-	-	-	C	-	-	-	HEAT repeats
NHLFHNML_01745	9.65e-59	-	-	-	S	-	-	-	Belongs to the LOG family
NHLFHNML_01746	3.28e-89	-	-	-	S	-	-	-	Bacterial PH domain
NHLFHNML_01747	4.19e-190	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
NHLFHNML_01748	1.38e-05	-	-	-	F	-	-	-	NUDIX domain
NHLFHNML_01749	1.89e-105	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
NHLFHNML_01750	2.64e-75	-	-	-	E	-	-	-	LysE type translocator
NHLFHNML_01751	3.9e-127	-	-	-	K	-	-	-	AraC family transcriptional regulator
NHLFHNML_01752	7.29e-18	-	-	-	-	-	-	-	-
NHLFHNML_01754	1.02e-120	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
NHLFHNML_01755	1.43e-177	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHLFHNML_01756	5.4e-200	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_01757	6.76e-16	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
NHLFHNML_01758	1.77e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
NHLFHNML_01759	2.95e-117	-	-	-	K	-	-	-	Virulence activator alpha C-term
NHLFHNML_01760	1.78e-195	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
NHLFHNML_01761	1.14e-94	-	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
NHLFHNML_01762	7.85e-159	-	-	-	-	-	-	-	-
NHLFHNML_01763	1.58e-55	-	-	-	-	-	-	-	-
NHLFHNML_01764	7.34e-271	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
NHLFHNML_01765	1.78e-56	-	-	-	-	-	-	-	-
NHLFHNML_01766	1.39e-88	-	-	-	-	-	-	-	-
NHLFHNML_01767	7.08e-136	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
NHLFHNML_01768	0.0	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHLFHNML_01769	1.28e-06	-	-	-	S	-	-	-	Putative methionine and alanine importer, small subunit
NHLFHNML_01770	2.78e-71	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
NHLFHNML_01772	5.72e-188	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
NHLFHNML_01773	1.67e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
NHLFHNML_01774	4.45e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
NHLFHNML_01775	1.49e-309	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
NHLFHNML_01776	2.43e-125	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	D,D-heptose 1,7-bisphosphate phosphatase
NHLFHNML_01777	7.17e-199	asbF	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
NHLFHNML_01778	8.91e-232	asbE	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHLFHNML_01779	3.69e-54	asbD	-	-	IQ	-	-	-	Phosphopantetheine attachment site
NHLFHNML_01780	7.19e-280	asbC	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	AMP-binding enzyme C-terminal domain
NHLFHNML_01781	0.0	asbB	-	-	Q	-	-	-	IucA / IucC family
NHLFHNML_01782	0.0	asbA	-	-	Q	-	-	-	Siderophore biosynthesis protein
NHLFHNML_01783	7.29e-77	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
NHLFHNML_01784	3.6e-265	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NHLFHNML_01785	2.73e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
NHLFHNML_01786	4.16e-235	ywcH1	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_01787	2.2e-172	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
NHLFHNML_01788	2.51e-235	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_01789	2.74e-132	yvdT	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_01790	4.41e-289	-	-	-	S	-	-	-	Acetyltransferase
NHLFHNML_01791	3.72e-143	-	-	CBM50	M	ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
NHLFHNML_01792	2.88e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
NHLFHNML_01793	1.16e-140	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
NHLFHNML_01794	1.23e-181	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
NHLFHNML_01795	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NHLFHNML_01796	8.73e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
NHLFHNML_01797	1.62e-187	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
NHLFHNML_01798	1.64e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
NHLFHNML_01799	5.09e-224	-	-	-	L	ko:K07496	-	ko00000	Transposase
NHLFHNML_01800	1.24e-199	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHLFHNML_01801	7.14e-210	-	-	-	M	-	-	-	3D domain
NHLFHNML_01802	1.57e-188	-	-	-	M	-	-	-	3D domain
NHLFHNML_01803	2.79e-165	yodH	-	-	Q	-	-	-	Methyltransferase
NHLFHNML_01804	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHLFHNML_01805	8.36e-115	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
NHLFHNML_01806	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHLFHNML_01807	3.03e-68	-	-	-	-	-	-	-	-
NHLFHNML_01808	3.97e-175	-	-	-	Q	-	-	-	Methyltransferase domain
NHLFHNML_01809	4.81e-94	yyaT	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_01810	3.33e-51	-	-	-	-	-	-	-	-
NHLFHNML_01811	6.88e-297	hint	6.5.1.3	-	S	ko:K14415	-	ko00000,ko01000,ko03016	tRNA-splicing ligase RtcB
NHLFHNML_01812	9.9e-105	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_01813	1.38e-97	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
NHLFHNML_01814	3.39e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHLFHNML_01815	6.36e-78	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
NHLFHNML_01816	1.62e-256	-	-	-	L	ko:K07496	-	ko00000	Transposase
NHLFHNML_01817	2.23e-201	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NHLFHNML_01818	7.3e-270	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
NHLFHNML_01819	1.72e-151	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
NHLFHNML_01820	2.48e-177	-	-	-	S	-	-	-	Sporulation protein YpjB (SpoYpjB)
NHLFHNML_01821	3.49e-139	ypjA	-	-	S	-	-	-	membrane
NHLFHNML_01822	3.57e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
NHLFHNML_01823	8.39e-159	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
NHLFHNML_01824	4.26e-118	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
NHLFHNML_01825	8.72e-105	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
NHLFHNML_01826	3.4e-126	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
NHLFHNML_01827	1.03e-289	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
NHLFHNML_01828	6.7e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHLFHNML_01829	1.01e-253	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
NHLFHNML_01830	2.83e-262	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHLFHNML_01831	3.98e-189	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHLFHNML_01832	1.41e-284	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHLFHNML_01833	1.24e-148	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosylanthranilate isomerase activity
NHLFHNML_01834	1.41e-166	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
NHLFHNML_01835	2.3e-231	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHLFHNML_01836	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHLFHNML_01837	3.24e-77	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NHLFHNML_01838	1.21e-246	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHLFHNML_01839	4.18e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHLFHNML_01840	5.37e-178	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
NHLFHNML_01841	6.26e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHLFHNML_01842	2.7e-230	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NHLFHNML_01843	2.24e-203	mqnA	4.2.1.151	-	S	ko:K11782	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NHLFHNML_01844	8.07e-202	ubiA	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
NHLFHNML_01845	6.12e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHLFHNML_01846	4.74e-73	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	heptaprenyl diphosphate synthase
NHLFHNML_01847	1.85e-48	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NHLFHNML_01848	6.78e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
NHLFHNML_01849	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NHLFHNML_01850	5.33e-171	yphF	-	-	-	-	-	-	-
NHLFHNML_01851	8.81e-10	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
NHLFHNML_01852	2.5e-52	-	-	-	S	-	-	-	Stage VI sporulation protein F
NHLFHNML_01853	3.58e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
NHLFHNML_01854	2.91e-132	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHLFHNML_01855	1.29e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
NHLFHNML_01857	1.68e-257	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
NHLFHNML_01858	7.57e-135	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	1-acyl-sn-glycerol-3-phosphate acyltransferase
NHLFHNML_01859	4.01e-168	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
NHLFHNML_01860	1.76e-314	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
NHLFHNML_01861	6.22e-209	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
NHLFHNML_01862	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NHLFHNML_01863	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NHLFHNML_01864	4.53e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NHLFHNML_01865	4.79e-35	-	-	-	-	-	-	-	-
NHLFHNML_01866	3.4e-145	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
NHLFHNML_01867	1.32e-224	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHLFHNML_01868	5.03e-230	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
NHLFHNML_01869	1.25e-302	gudB	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NHLFHNML_01870	3.93e-226	-	-	-	-	-	-	-	-
NHLFHNML_01871	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NHLFHNML_01872	4.48e-161	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_01873	1.11e-138	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHLFHNML_01874	8.85e-212	ycgE	-	-	K	ko:K22491	-	ko00000,ko03000	MerR family transcriptional regulator
NHLFHNML_01875	1.74e-179	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NHLFHNML_01876	2.33e-281	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHLFHNML_01878	8.81e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHLFHNML_01879	3.38e-251	-	-	GT4	M	ko:K13678	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NHLFHNML_01880	2.18e-287	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl Transferase
NHLFHNML_01881	1.44e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_01882	7.55e-69	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_01885	1.12e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
NHLFHNML_01886	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
NHLFHNML_01887	5.87e-222	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
NHLFHNML_01888	2.28e-57	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
NHLFHNML_01889	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHLFHNML_01890	7.52e-315	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHLFHNML_01891	5e-175	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NHLFHNML_01893	5.18e-122	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
NHLFHNML_01894	5.59e-175	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NHLFHNML_01895	2.15e-239	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_01896	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_01897	2.69e-167	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_01898	1.13e-272	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NHLFHNML_01899	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
NHLFHNML_01900	2.06e-125	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NHLFHNML_01901	3.81e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHLFHNML_01902	5.76e-102	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
NHLFHNML_01903	2.51e-130	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
NHLFHNML_01904	6.78e-269	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NHLFHNML_01905	1.46e-73	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
NHLFHNML_01906	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
NHLFHNML_01907	2.13e-101	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
NHLFHNML_01908	5.4e-59	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHLFHNML_01909	1.44e-157	-	-	-	S	-	-	-	membrane
NHLFHNML_01910	1.89e-59	-	-	-	S	-	-	-	ATP synthase, subunit b
NHLFHNML_01911	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
NHLFHNML_01912	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHLFHNML_01913	5.16e-215	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
NHLFHNML_01914	0.0	acoD	-	-	C	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
NHLFHNML_01915	1.67e-135	-	-	-	K	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
NHLFHNML_01916	1.78e-127	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHLFHNML_01917	9.2e-161	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHLFHNML_01918	1.52e-105	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
NHLFHNML_01919	4.15e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHLFHNML_01920	2.54e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHLFHNML_01921	1.18e-140	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
NHLFHNML_01922	5.6e-247	-	-	-	I	-	-	-	3-hydroxyisobutyryl-CoA hydrolase
NHLFHNML_01923	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_01924	7.41e-201	hgd	1.1.1.31, 1.1.1.60	-	I	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	ko00000,ko00001,ko01000	3-hydroxyisobutyrate dehydrogenase
NHLFHNML_01925	6.14e-205	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NHLFHNML_01926	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
NHLFHNML_01927	5.99e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
NHLFHNML_01928	7.21e-261	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHLFHNML_01929	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHLFHNML_01930	1.51e-122	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHLFHNML_01931	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHLFHNML_01932	4.41e-155	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
NHLFHNML_01933	9.73e-252	-	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
NHLFHNML_01934	1.53e-199	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
NHLFHNML_01935	3e-185	-	-	-	P	ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
NHLFHNML_01936	2.44e-243	cytR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
NHLFHNML_01937	0.0	-	-	-	M	-	-	-	glycoside hydrolase family 81
NHLFHNML_01938	9.24e-146	-	-	-	S	-	-	-	Cupin
NHLFHNML_01939	3.99e-07	liaI	-	-	-	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	-
NHLFHNML_01940	1.08e-131	-	-	-	-	-	-	-	-
NHLFHNML_01941	4.96e-159	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
NHLFHNML_01942	2.79e-234	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_01943	7.73e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHLFHNML_01944	7.02e-141	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
NHLFHNML_01945	1.43e-170	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
NHLFHNML_01946	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
NHLFHNML_01948	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
NHLFHNML_01949	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
NHLFHNML_01950	4.08e-176	-	-	-	S	ko:K06976	-	ko00000	GNAT acetyltransferase
NHLFHNML_01951	3.14e-185	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
NHLFHNML_01952	2.24e-227	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHLFHNML_01953	6.94e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
NHLFHNML_01954	6.91e-55	M1-485	-	-	S	-	-	-	Membrane
NHLFHNML_01955	5.41e-253	ysdC_3	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	M42 glutamyl aminopeptidase
NHLFHNML_01956	2.95e-99	-	-	-	-	-	-	-	-
NHLFHNML_01957	3.82e-95	-	-	-	-	-	-	-	-
NHLFHNML_01958	4.02e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
NHLFHNML_01959	8.62e-228	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
NHLFHNML_01960	1.22e-227	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
NHLFHNML_01961	1.6e-109	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
NHLFHNML_01962	5.5e-259	siaT_3	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
NHLFHNML_01963	4.58e-116	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
NHLFHNML_01964	1.15e-138	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NHLFHNML_01965	5.61e-224	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
NHLFHNML_01966	1.49e-133	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
NHLFHNML_01967	1.91e-237	-	-	-	-	-	-	-	-
NHLFHNML_01968	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
NHLFHNML_01969	0.0	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
NHLFHNML_01970	9.41e-94	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHLFHNML_01971	2.12e-56	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_01972	3.47e-286	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
NHLFHNML_01973	4.25e-248	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHLFHNML_01974	1.15e-29	-	-	-	-	-	-	-	-
NHLFHNML_01975	8.17e-267	gatD	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
NHLFHNML_01976	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
NHLFHNML_01977	1.02e-89	-	-	-	-	-	-	-	-
NHLFHNML_01978	1.25e-117	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
NHLFHNML_01979	2.47e-222	-	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
NHLFHNML_01980	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NHLFHNML_01981	1.76e-196	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
NHLFHNML_01982	5.63e-145	-	-	-	-	-	-	-	-
NHLFHNML_01983	1.57e-134	desR	-	-	K	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
NHLFHNML_01984	1.29e-235	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_01985	4.99e-275	-	-	-	G	-	-	-	Transmembrane secretion effector
NHLFHNML_01986	0.0	-	-	-	T	-	-	-	COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NHLFHNML_01987	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NHLFHNML_01988	7.1e-309	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
NHLFHNML_01989	7.65e-278	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NHLFHNML_01990	0.0	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
NHLFHNML_01991	1.69e-287	-	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_01992	1.62e-228	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
NHLFHNML_01994	5.46e-115	-	-	-	-	-	-	-	-
NHLFHNML_01995	1.81e-57	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
NHLFHNML_01996	4.63e-209	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NHLFHNML_01997	5.62e-75	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
NHLFHNML_01998	4.93e-107	-	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein kinase domain
NHLFHNML_01999	1.81e-79	-	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein kinase domain
NHLFHNML_02000	4.68e-104	-	-	-	S	ko:K06385	-	ko00000	Stage II sporulation protein P (SpoIIP)
NHLFHNML_02001	3.73e-173	-	-	-	K	-	-	-	acetyltransferase
NHLFHNML_02002	7.21e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_02003	1.73e-275	-	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
NHLFHNML_02004	1.2e-260	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
NHLFHNML_02005	0.0	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
NHLFHNML_02006	3.9e-35	-	-	-	-	-	-	-	-
NHLFHNML_02007	1.9e-147	ypgQ	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
NHLFHNML_02008	3.07e-268	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NHLFHNML_02009	1.8e-117	ywmF	-	-	S	-	-	-	Peptidase M50
NHLFHNML_02010	2.15e-48	ydaS	-	-	S	-	-	-	membrane
NHLFHNML_02012	3.42e-110	M1-753	-	-	M	-	-	-	FR47-like protein
NHLFHNML_02013	1.34e-40	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
NHLFHNML_02014	3.26e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
NHLFHNML_02015	2.01e-103	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
NHLFHNML_02016	2.17e-112	-	-	-	K	ko:K11922	-	ko00000,ko03000	Regulates the succiny-lCoA synthetase operon
NHLFHNML_02017	9.08e-294	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
NHLFHNML_02018	1.72e-259	-	-	-	P	-	-	-	Sulfatase
NHLFHNML_02019	2.48e-60	ptbA	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, glucose subfamily, IIA
NHLFHNML_02020	3.44e-130	-	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Putative N-acetylmannosamine-6-phosphate epimerase
NHLFHNML_02021	3.01e-156	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
NHLFHNML_02022	2.07e-139	-	-	-	K	-	-	-	LysR substrate binding domain
NHLFHNML_02023	9.73e-193	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
NHLFHNML_02024	1.67e-86	-	-	-	E	ko:K07032	-	ko00000	lactoylglutathione lyase activity
NHLFHNML_02025	0.0	-	-	-	M	-	-	-	Sulfatase
NHLFHNML_02026	0.0	-	-	-	E	-	-	-	Aminotransferase class-V
NHLFHNML_02027	6.52e-115	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHLFHNML_02028	1.91e-132	-	-	-	V	-	-	-	Beta-lactamase
NHLFHNML_02029	1.84e-187	yfhB	-	-	S	-	-	-	PhzF family
NHLFHNML_02030	1.71e-83	-	-	-	S	-	-	-	Protein of unknown function, DUF393
NHLFHNML_02031	2.53e-241	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_02032	1.95e-220	-	-	-	K	-	-	-	Cupin domain
NHLFHNML_02033	1.57e-180	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLFHNML_02034	2.45e-268	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_02035	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
NHLFHNML_02036	2.28e-219	ugpA7	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02037	3.44e-199	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02038	2.6e-181	inoDHR	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLFHNML_02039	4.83e-129	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_02040	1.93e-266	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_02041	1.46e-284	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_02042	8.52e-212	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_02043	1.31e-276	-	3.2.1.180	GH88	O	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
NHLFHNML_02044	1.95e-28	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02045	5.9e-125	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02046	1.74e-189	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02047	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
NHLFHNML_02049	7.17e-144	-	-	-	M	-	-	-	Peptidase family M23
NHLFHNML_02052	4.13e-110	mutT	3.6.1.13, 3.6.1.55	-	L	ko:K01515,ko:K03574	ko00230,map00230	ko00000,ko00001,ko01000,ko03400	nUDIX hydrolase
NHLFHNML_02053	2.21e-311	ywoF	-	-	P	-	-	-	Right handed beta helix region
NHLFHNML_02054	1.89e-200	-	-	-	EG	-	-	-	EamA-like transporter family
NHLFHNML_02055	7.59e-91	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_02056	3.15e-23	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	transport system, permease component
NHLFHNML_02057	5.79e-37	XK27_06950	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_02058	1.93e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_02059	7.53e-73	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
NHLFHNML_02060	1.59e-205	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02061	2.9e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NHLFHNML_02062	9.18e-241	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_02063	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02064	3.44e-262	ysh1	-	-	J	-	-	-	Metallo-beta-lactamase superfamily
NHLFHNML_02065	3.69e-187	M1-276	-	-	-	-	-	-	-
NHLFHNML_02066	8.48e-106	-	-	-	-	-	-	-	-
NHLFHNML_02067	0.0	-	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHLFHNML_02068	1.44e-28	topA2	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
NHLFHNML_02069	1.07e-52	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
NHLFHNML_02070	1.3e-14	mazE	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
NHLFHNML_02071	1.57e-14	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	Thioesterase superfamily
NHLFHNML_02072	2.91e-228	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
NHLFHNML_02073	5.34e-181	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHLFHNML_02074	3.98e-295	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
NHLFHNML_02075	5.26e-259	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
NHLFHNML_02076	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
NHLFHNML_02077	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
NHLFHNML_02078	5.7e-199	ssuB	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NHLFHNML_02079	1.01e-133	ssuC_2	-	-	P	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02080	2.46e-221	ssuA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NHLFHNML_02081	7.8e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHLFHNML_02082	2.74e-101	yybA	-	-	K	-	-	-	transcriptional
NHLFHNML_02083	5.53e-119	-	-	-	S	-	-	-	VanZ like family
NHLFHNML_02084	3.19e-148	-	-	-	-	-	-	-	-
NHLFHNML_02085	2.31e-48	-	-	-	G	-	-	-	PTS HPr component phosphorylation site
NHLFHNML_02086	4.16e-298	-	-	-	E	-	-	-	SAF
NHLFHNML_02087	1.1e-88	-	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
NHLFHNML_02088	8.78e-115	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
NHLFHNML_02089	1.61e-229	-	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
NHLFHNML_02090	2.59e-77	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NHLFHNML_02091	1.16e-214	-	-	-	K	-	-	-	Putative sugar-binding domain
NHLFHNML_02092	0.0	acyII	3.5.1.11	-	S	ko:K01434	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000,ko01002	Penicillin amidase
NHLFHNML_02093	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NHLFHNML_02094	1.55e-66	yerC	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02095	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
NHLFHNML_02096	4.58e-247	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
NHLFHNML_02097	2.8e-205	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NHLFHNML_02098	4.62e-188	gbuB	-	-	P	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
NHLFHNML_02099	5.92e-280	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
NHLFHNML_02100	2.49e-123	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
NHLFHNML_02103	3.72e-88	-	-	-	-	-	-	-	-
NHLFHNML_02104	6.18e-69	-	-	-	-	-	-	-	-
NHLFHNML_02105	8.08e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4926)
NHLFHNML_02106	6.99e-65	-	-	-	-	-	-	-	-
NHLFHNML_02107	3.74e-67	-	-	-	-	-	-	-	-
NHLFHNML_02108	1.11e-14	-	-	-	L	ko:K07483	-	ko00000	Transposase
NHLFHNML_02109	8.11e-89	-	-	-	S	-	-	-	Protein of unknown function, DUF600
NHLFHNML_02110	5.27e-37	-	-	-	S	-	-	-	nuclease activity
NHLFHNML_02111	1.02e-98	-	-	-	S	-	-	-	LXG domain of WXG superfamily
NHLFHNML_02112	1.03e-76	-	-	-	-	-	-	-	-
NHLFHNML_02113	3.87e-51	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
NHLFHNML_02114	4.74e-43	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
NHLFHNML_02116	2.5e-236	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
NHLFHNML_02117	2.5e-278	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
NHLFHNML_02118	1.66e-217	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
NHLFHNML_02119	3.54e-140	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
NHLFHNML_02120	1.18e-253	-	-	-	T	-	-	-	Signal transduction histidine kinase
NHLFHNML_02121	6.18e-115	ttr	-	-	K	-	-	-	GCN5 family acetyltransferase
NHLFHNML_02122	2e-196	fhuD9	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NHLFHNML_02123	4.68e-259	-	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
NHLFHNML_02124	3.68e-294	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
NHLFHNML_02125	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
NHLFHNML_02126	2.24e-126	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHLFHNML_02127	9.28e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
NHLFHNML_02128	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHLFHNML_02129	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHLFHNML_02130	6.66e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHLFHNML_02131	5.87e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHLFHNML_02132	1.13e-164	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
NHLFHNML_02133	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHLFHNML_02134	1.17e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHLFHNML_02135	2.26e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHLFHNML_02136	1.27e-164	-	-	-	S	-	-	-	CAAX protease self-immunity
NHLFHNML_02137	6.57e-125	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHLFHNML_02138	3.32e-154	-	-	-	S	-	-	-	PFAM AIG2 family protein
NHLFHNML_02139	1.5e-128	-	-	-	-	-	-	-	-
NHLFHNML_02140	9.63e-88	-	-	-	S	-	-	-	Calcium/calmodulin dependent protein kinase II association domain
NHLFHNML_02141	1.02e-42	yebG	-	-	S	-	-	-	NETI protein
NHLFHNML_02143	2.1e-90	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
NHLFHNML_02144	1.84e-07	-	-	-	T	-	-	-	SpoVT / AbrB like domain
NHLFHNML_02145	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
NHLFHNML_02146	7.13e-89	-	-	-	S	ko:K07794	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctB family
NHLFHNML_02147	3.73e-239	-	-	-	S	ko:K07795	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter family receptor
NHLFHNML_02148	3.15e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NHLFHNML_02149	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NHLFHNML_02150	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
NHLFHNML_02151	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NHLFHNML_02152	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NHLFHNML_02153	1.51e-296	-	-	-	G	-	-	-	Major facilitator Superfamily
NHLFHNML_02156	2.79e-126	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
NHLFHNML_02157	2.44e-266	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
NHLFHNML_02158	3.1e-168	mta	-	-	K	-	-	-	transcriptional
NHLFHNML_02159	5.3e-150	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_02160	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
NHLFHNML_02161	1.85e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NHLFHNML_02162	1.17e-167	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_02163	8.9e-168	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NHLFHNML_02164	2.56e-111	-	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
NHLFHNML_02165	1.31e-135	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
NHLFHNML_02166	2.42e-198	mqnD	-	-	S	ko:K11785	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NHLFHNML_02167	2.36e-145	mqnB	3.2.2.26	-	F	ko:K11783	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
NHLFHNML_02168	0.0	lipA1	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHLFHNML_02169	1.87e-87	-	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
NHLFHNML_02170	2e-142	-	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
NHLFHNML_02171	3.42e-65	-	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
NHLFHNML_02173	1.07e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
NHLFHNML_02174	0.0	-	-	-	M	-	-	-	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NHLFHNML_02175	4.41e-208	-	-	-	Q	-	-	-	calcium- and calmodulin-responsive adenylate cyclase activity
NHLFHNML_02176	2.32e-199	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Substrate binding domain of ABC-type glycine betaine transport system
NHLFHNML_02177	6.28e-130	-	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
NHLFHNML_02178	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NHLFHNML_02179	3.08e-285	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
NHLFHNML_02180	7.2e-173	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
NHLFHNML_02181	4.64e-159	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHLFHNML_02182	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NHLFHNML_02183	1.15e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHLFHNML_02184	0.0	-	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
NHLFHNML_02185	9.68e-26	-	-	-	-	-	-	-	-
NHLFHNML_02186	2.53e-284	cypA	-	-	C	ko:K15468	-	ko00000,ko01008	Cytochrome P450
NHLFHNML_02187	0.0	abgT_2	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
NHLFHNML_02188	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
NHLFHNML_02189	5.84e-129	-	-	-	Q	-	-	-	Isochorismatase family
NHLFHNML_02190	1.4e-98	ygaO	-	-	-	-	-	-	-
NHLFHNML_02191	1.3e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_02192	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
NHLFHNML_02194	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
NHLFHNML_02195	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
NHLFHNML_02196	1.17e-215	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
NHLFHNML_02197	1.28e-190	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
NHLFHNML_02198	8.69e-67	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHLFHNML_02199	0.0	-	-	-	S	-	-	-	proteins of the AP superfamily
NHLFHNML_02200	1.2e-284	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NHLFHNML_02201	1.51e-87	-	-	-	-	-	-	-	-
NHLFHNML_02202	2.03e-221	-	-	-	S	-	-	-	Phosphotransferase enzyme family
NHLFHNML_02203	1.68e-275	-	-	-	G	-	-	-	Transmembrane secretion effector
NHLFHNML_02204	1.2e-32	-	-	-	S	-	-	-	YfhD-like protein
NHLFHNML_02205	8.02e-84	-	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
NHLFHNML_02206	3.72e-139	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
NHLFHNML_02207	1.41e-168	dhaK	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dihydroxyacetone kinase DhaK, subunit
NHLFHNML_02208	1.44e-107	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
NHLFHNML_02209	4.49e-97	rmaD	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
NHLFHNML_02210	2.21e-258	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHLFHNML_02211	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHLFHNML_02212	6.1e-294	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
NHLFHNML_02213	5.98e-55	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_02214	0.0	-	2.7.1.194	-	GKT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	COG3711 Transcriptional antiterminator
NHLFHNML_02215	2.19e-231	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHLFHNML_02216	4.09e-145	XK27_07680	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLFHNML_02217	4.42e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_02218	3.14e-26	yisL	-	-	S	-	-	-	UPF0344 protein
NHLFHNML_02219	3.56e-149	-	-	-	C	-	-	-	Nitroreductase family
NHLFHNML_02220	4.45e-79	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHLFHNML_02221	1.51e-74	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NHLFHNML_02222	4.34e-104	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHLFHNML_02223	3.59e-49	ydfG	-	-	S	-	-	-	Carboxymuconolactone decarboxylase family
NHLFHNML_02224	1.78e-166	-	-	-	K	ko:K03088	-	ko00000,ko03021	TIGRFAM RNA polymerase sigma factor, sigma-70 family
NHLFHNML_02225	2.11e-82	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
NHLFHNML_02226	6.69e-213	-	-	-	K	-	-	-	LysR substrate binding domain
NHLFHNML_02227	7.79e-237	dapB	1.4.1.12, 1.4.1.26	-	S	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	ko00000,ko00001,ko01000	Dihydrodipicolinate reductase, N-terminus
NHLFHNML_02228	2.47e-308	-	-	-	C	-	-	-	Na+/H+ antiporter family
NHLFHNML_02229	2.89e-100	-	-	-	S	-	-	-	glyoxalase bleomycin resistance protein dioxygenase
NHLFHNML_02230	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
NHLFHNML_02231	2.07e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
NHLFHNML_02232	3.93e-244	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
NHLFHNML_02234	2.09e-131	ytqB	-	-	J	-	-	-	Putative rRNA methylase
NHLFHNML_02235	9.47e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
NHLFHNML_02236	1.3e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
NHLFHNML_02237	3.24e-96	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NHLFHNML_02238	2.35e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHLFHNML_02239	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NHLFHNML_02241	5.08e-192	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NHLFHNML_02242	9.36e-229	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NHLFHNML_02243	6.58e-175	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NHLFHNML_02244	1.53e-175	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHLFHNML_02245	1.96e-108	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
NHLFHNML_02246	1.58e-284	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
NHLFHNML_02247	5.16e-110	ywpF	-	-	S	-	-	-	YwpF-like protein
NHLFHNML_02249	7.16e-280	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHLFHNML_02250	2.15e-144	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
NHLFHNML_02251	1.52e-154	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
NHLFHNML_02252	2.62e-138	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
NHLFHNML_02253	9.26e-222	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
NHLFHNML_02254	2.81e-191	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_02255	4.99e-195	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_02256	1.01e-206	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_02257	1.37e-127	pgpB3	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
NHLFHNML_02258	1.61e-296	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHLFHNML_02259	1.49e-97	-	-	-	S	-	-	-	Putative small multi-drug export protein
NHLFHNML_02260	1.4e-95	-	-	-	S	-	-	-	DinB superfamily
NHLFHNML_02261	1.34e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
NHLFHNML_02262	1.42e-108	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
NHLFHNML_02263	3.16e-207	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NHLFHNML_02264	1.71e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
NHLFHNML_02265	8.46e-49	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
NHLFHNML_02267	1.26e-26	-	-	-	-	-	-	-	-
NHLFHNML_02268	5.72e-90	yugN	-	-	S	-	-	-	YugN-like family
NHLFHNML_02269	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
NHLFHNML_02270	7.51e-262	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
NHLFHNML_02271	4.72e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
NHLFHNML_02272	2.41e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
NHLFHNML_02273	7.86e-77	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
NHLFHNML_02274	8.68e-257	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
NHLFHNML_02275	6.03e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHLFHNML_02276	6.4e-281	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
NHLFHNML_02277	4.23e-110	alaR	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02278	1.06e-110	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHLFHNML_02279	1.73e-182	-	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
NHLFHNML_02280	1.81e-55	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHLFHNML_02281	5.83e-292	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
NHLFHNML_02282	5.93e-60	-	-	-	-	-	-	-	-
NHLFHNML_02283	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NHLFHNML_02284	1.5e-101	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
NHLFHNML_02285	1.84e-140	yuiC	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02286	2.61e-61	yuiB	-	-	S	-	-	-	Putative membrane protein
NHLFHNML_02287	1.27e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NHLFHNML_02288	5.27e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
NHLFHNML_02289	1.52e-262	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
NHLFHNML_02290	2.29e-92	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NHLFHNML_02291	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
NHLFHNML_02292	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
NHLFHNML_02293	7.45e-195	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
NHLFHNML_02294	1.36e-138	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
NHLFHNML_02295	7.18e-79	yutM	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
NHLFHNML_02296	3.32e-13	-	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
NHLFHNML_02297	1.47e-266	mqnE	2.5.1.120	-	H	ko:K18285	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
NHLFHNML_02298	1.52e-204	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHLFHNML_02299	9.92e-57	-	-	-	-	-	-	-	-
NHLFHNML_02300	3.63e-54	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
NHLFHNML_02301	0.0	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
NHLFHNML_02302	5.36e-68	yuzD	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02303	4.25e-49	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
NHLFHNML_02304	4.67e-202	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHLFHNML_02305	4.81e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NHLFHNML_02306	1.03e-304	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NHLFHNML_02307	3.55e-258	yutH	-	-	S	-	-	-	Spore coat protein
NHLFHNML_02308	1.37e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
NHLFHNML_02309	1.59e-165	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHLFHNML_02310	1.71e-95	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
NHLFHNML_02311	1.79e-59	-	-	-	-	-	-	-	-
NHLFHNML_02312	6.09e-67	yutD	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02313	4.63e-119	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHLFHNML_02314	7.35e-221	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHLFHNML_02315	4.04e-255	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
NHLFHNML_02316	0.0	-	-	-	C	ko:K18218	-	ko00000,ko00002,ko01504,ko02000	Na+/H+ antiporter family
NHLFHNML_02317	1.38e-175	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
NHLFHNML_02318	2.2e-115	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHLFHNML_02319	2.84e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHLFHNML_02320	7.97e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
NHLFHNML_02321	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHLFHNML_02322	1.52e-174	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
NHLFHNML_02323	1.59e-211	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
NHLFHNML_02324	1.39e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
NHLFHNML_02325	1.12e-68	-	-	-	-	-	-	-	-
NHLFHNML_02326	1.92e-202	-	-	-	-	-	-	-	-
NHLFHNML_02329	4.25e-30	-	-	-	-	-	-	-	-
NHLFHNML_02331	2.94e-51	-	-	-	-	-	-	-	-
NHLFHNML_02332	7.29e-196	-	-	-	S	-	-	-	LXG domain of WXG superfamily
NHLFHNML_02333	8.5e-55	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
NHLFHNML_02334	4.37e-45	-	-	-	S	-	-	-	Pathogenicity locus
NHLFHNML_02335	1.32e-102	-	-	-	H	-	-	-	RibD C-terminal domain
NHLFHNML_02336	3.03e-196	-	-	-	S	-	-	-	Phosphotransferase enzyme family
NHLFHNML_02337	7.66e-116	yvbU	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02338	2.33e-144	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
NHLFHNML_02339	1.63e-233	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
NHLFHNML_02340	2.56e-182	msmR	-	-	K	-	-	-	AraC family transcriptional regulator
NHLFHNML_02341	6.19e-239	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
NHLFHNML_02342	9.45e-180	-	-	-	Q	-	-	-	Methyltransferase domain
NHLFHNML_02343	2.65e-52	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
NHLFHNML_02344	6.62e-69	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
NHLFHNML_02345	8.78e-23	-	-	-	S	-	-	-	YhfH-like protein
NHLFHNML_02346	2.09e-305	aceA	4.1.3.1	-	C	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Isocitrate lyase
NHLFHNML_02347	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
NHLFHNML_02348	2.18e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
NHLFHNML_02349	1.44e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHLFHNML_02350	5.41e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
NHLFHNML_02351	2.3e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHLFHNML_02352	4.09e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHLFHNML_02353	1.07e-212	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NHLFHNML_02354	1.49e-120	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
NHLFHNML_02355	1.74e-191	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
NHLFHNML_02356	8.61e-147	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
NHLFHNML_02357	3.16e-234	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHLFHNML_02358	6.74e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NHLFHNML_02359	2.29e-81	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
NHLFHNML_02360	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
NHLFHNML_02361	9.31e-269	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
NHLFHNML_02362	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
NHLFHNML_02363	2.46e-273	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
NHLFHNML_02364	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
NHLFHNML_02365	2.8e-154	-	-	-	S	-	-	-	Glycosyltransferase like family
NHLFHNML_02366	6.42e-140	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHLFHNML_02367	1.91e-122	-	-	-	M	-	-	-	3D domain
NHLFHNML_02368	2.03e-280	-	-	-	JM	-	-	-	Bacterial transferase hexapeptide (six repeats)
NHLFHNML_02369	2.48e-162	frlR3	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
NHLFHNML_02370	3.29e-181	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
NHLFHNML_02371	6.63e-108	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_02372	4.58e-305	ykoH	-	-	T	-	-	-	Histidine kinase
NHLFHNML_02373	2.69e-148	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NHLFHNML_02374	1.58e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
NHLFHNML_02375	4.65e-150	-	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Glycerate kinase family
NHLFHNML_02376	3.61e-130	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
NHLFHNML_02378	0.0	-	-	-	I	-	-	-	radical SAM domain protein
NHLFHNML_02379	0.0	-	1.3.98.3	-	H	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of porphyrin-containing compound
NHLFHNML_02381	3.5e-170	yafE	-	-	Q	-	-	-	methyltransferase
NHLFHNML_02383	2.9e-114	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
NHLFHNML_02384	9.45e-281	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
NHLFHNML_02385	9.61e-125	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NHLFHNML_02386	1.16e-213	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
NHLFHNML_02387	6.41e-160	-	-	-	M	-	-	-	Glycosyl transferases group 1
NHLFHNML_02388	2.41e-129	-	-	-	-	-	-	-	-
NHLFHNML_02389	3.91e-131	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
NHLFHNML_02390	5.51e-153	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
NHLFHNML_02391	1.41e-144	-	-	-	M	-	-	-	Glycosyl transferase family 2
NHLFHNML_02392	1.52e-301	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHLFHNML_02393	1.02e-84	ybbJ	-	-	J	-	-	-	acetyltransferase
NHLFHNML_02394	8.15e-250	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHLFHNML_02395	1.07e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
NHLFHNML_02396	2.58e-33	-	-	-	-	-	-	-	-
NHLFHNML_02397	4.06e-306	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
NHLFHNML_02398	6.24e-119	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
NHLFHNML_02399	2.4e-155	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
NHLFHNML_02400	2.6e-208	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
NHLFHNML_02401	1.62e-130	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
NHLFHNML_02402	8.16e-289	dgoD	4.2.1.6	-	M	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
NHLFHNML_02403	8.06e-247	gntU	-	-	EG	ko:K03299,ko:K06156	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NHLFHNML_02404	1.99e-197	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NHLFHNML_02405	1.9e-113	-	-	-	S	-	-	-	Predicted membrane protein (DUF2243)
NHLFHNML_02406	9.85e-159	-	-	-	S	ko:K02351	-	ko00000	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
NHLFHNML_02407	2.68e-293	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
NHLFHNML_02408	9.77e-160	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_02409	1.95e-213	-	-	-	K	-	-	-	DJ-1/PfpI family
NHLFHNML_02410	8.33e-140	-	-	-	S	-	-	-	Predicted membrane protein (DUF2306)
NHLFHNML_02411	2.05e-255	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
NHLFHNML_02412	4.02e-94	-	-	-	S	-	-	-	VanZ like family
NHLFHNML_02413	1.92e-141	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
NHLFHNML_02415	1.78e-105	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NHLFHNML_02416	5.94e-164	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHLFHNML_02417	0.0	-	-	-	V	-	-	-	SNF2 family N-terminal domain
NHLFHNML_02420	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
NHLFHNML_02421	1.43e-112	-	-	-	-	-	-	-	-
NHLFHNML_02422	2.72e-194	-	-	-	-	-	-	-	-
NHLFHNML_02423	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
NHLFHNML_02424	5.45e-29	-	-	-	-	-	-	-	-
NHLFHNML_02425	3.89e-284	bbsF_2	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	acyl-CoA transferases carnitine dehydratase
NHLFHNML_02426	6.35e-146	-	-	-	K	-	-	-	FCD domain
NHLFHNML_02427	1.31e-202	-	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
NHLFHNML_02428	2.6e-131	ybbH	-	-	K	-	-	-	RpiR family transcriptional regulator
NHLFHNML_02429	6.83e-228	-	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NHLFHNML_02430	7.1e-162	garR	1.1.1.60	-	I	ko:K00042	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NHLFHNML_02431	4.97e-236	-	-	-	S	-	-	-	Putative nucleotide-binding of sugar-metabolising enzyme
NHLFHNML_02432	8.1e-281	hmrA	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
NHLFHNML_02433	7.78e-201	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
NHLFHNML_02434	3.91e-145	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
NHLFHNML_02435	1.99e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHLFHNML_02436	1.07e-213	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NHLFHNML_02438	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NHLFHNML_02439	0.0	aguA	3.2.1.139	-	G	ko:K01235	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 67 family
NHLFHNML_02440	1.09e-223	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02441	6.62e-198	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NHLFHNML_02442	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_02443	5.89e-145	-	-	-	S	-	-	-	Protein of unknown function, DUF624
NHLFHNML_02444	1.94e-248	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
NHLFHNML_02445	8.66e-43	-	-	-	D	-	-	-	nuclear chromosome segregation
NHLFHNML_02447	3.27e-276	hutI	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
NHLFHNML_02448	8.29e-252	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
NHLFHNML_02449	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NHLFHNML_02450	4.03e-215	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_02451	8.22e-193	-	-	-	EP	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_02452	3.73e-240	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_02453	3.03e-242	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_02454	7.64e-222	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
NHLFHNML_02455	3.91e-307	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
NHLFHNML_02456	4.63e-175	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02457	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
NHLFHNML_02458	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
NHLFHNML_02459	8.59e-249	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
NHLFHNML_02460	3.52e-274	xylR5	-	-	GK	-	-	-	ROK family
NHLFHNML_02461	9.48e-157	-	-	-	S	ko:K09992	-	ko00000	Trehalose utilisation
NHLFHNML_02462	1.46e-282	yrbE	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_02463	0.0	-	-	-	KT	ko:K09684	-	ko00000,ko03000	PucR C-terminal helix-turn-helix domain
NHLFHNML_02464	6e-139	-	-	-	E	-	-	-	Asp/Glu/Hydantoin racemase
NHLFHNML_02465	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
NHLFHNML_02466	3.89e-243	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
NHLFHNML_02467	5.51e-213	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
NHLFHNML_02468	5.63e-145	-	-	-	E	ko:K14591	-	ko00000	AroM protein
NHLFHNML_02469	7.02e-218	-	-	-	E	-	-	-	Thermophilic metalloprotease (M29)
NHLFHNML_02470	2.11e-263	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
NHLFHNML_02471	2.4e-42	-	5.3.2.6	-	S	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Tautomerase enzyme
NHLFHNML_02472	7.42e-205	citS	2.7.13.3	-	T	ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NHLFHNML_02473	1.16e-85	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
NHLFHNML_02474	9.44e-184	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
NHLFHNML_02475	4.57e-63	-	-	-	S	ko:K07794	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctB family
NHLFHNML_02476	9.77e-280	tctA	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
NHLFHNML_02477	1.61e-256	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	chromate transporter, chromate ion transporter
NHLFHNML_02478	6.94e-59	M1-594	-	-	S	-	-	-	Thiamine-binding protein
NHLFHNML_02479	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHLFHNML_02480	1.82e-309	-	-	-	-	-	-	-	-
NHLFHNML_02482	5.75e-289	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
NHLFHNML_02483	8.25e-182	-	2.7.1.196, 2.7.1.205	-	K	ko:K02760,ko:K20480	ko00500,ko02024,ko02060,map00500,map02024,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	sequence-specific DNA binding
NHLFHNML_02484	7.18e-153	yflK	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02486	2.72e-300	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
NHLFHNML_02487	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHLFHNML_02488	5.08e-72	nirD	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
NHLFHNML_02489	0.0	nirB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHLFHNML_02490	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHLFHNML_02491	3.05e-280	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
NHLFHNML_02492	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
NHLFHNML_02494	2.4e-191	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NHLFHNML_02495	5.78e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHLFHNML_02496	1.13e-81	-	-	-	P	ko:K05571	-	ko00000,ko02000	Na+/H+ antiporter subunit
NHLFHNML_02497	4.41e-52	-	-	-	P	ko:K05570	-	ko00000,ko02000	Multiple resistance and pH regulation protein F (MrpF / PhaF)
NHLFHNML_02498	8.91e-106	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHLFHNML_02499	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHLFHNML_02500	1.13e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHLFHNML_02501	4.26e-93	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHLFHNML_02502	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHLFHNML_02504	1.52e-125	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
NHLFHNML_02505	3.63e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHLFHNML_02506	2.58e-188	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHLFHNML_02507	2.17e-62	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
NHLFHNML_02508	4.08e-137	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHLFHNML_02509	8.22e-138	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
NHLFHNML_02510	7.46e-81	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHLFHNML_02511	8.76e-201	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
NHLFHNML_02512	1.62e-172	-	-	-	S	-	-	-	Methyltransferase domain
NHLFHNML_02513	3.39e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHLFHNML_02514	3.02e-129	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
NHLFHNML_02515	9.98e-140	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
NHLFHNML_02516	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
NHLFHNML_02517	9.62e-09	-	-	-	S	-	-	-	YqzM-like protein
NHLFHNML_02518	6.51e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
NHLFHNML_02519	1.15e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
NHLFHNML_02520	4.87e-260	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NHLFHNML_02521	1.19e-261	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
NHLFHNML_02522	1.03e-68	-	-	-	-	-	-	-	-
NHLFHNML_02523	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHLFHNML_02524	7.46e-279	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
NHLFHNML_02525	4.19e-239	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHLFHNML_02526	2.88e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHLFHNML_02527	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
NHLFHNML_02528	3.2e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHLFHNML_02529	1.86e-217	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
NHLFHNML_02530	2.03e-167	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHLFHNML_02531	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
NHLFHNML_02532	7.36e-173	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
NHLFHNML_02533	1.2e-280	gltT	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHLFHNML_02534	3.35e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHLFHNML_02535	5.14e-217	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
NHLFHNML_02536	1.39e-204	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
NHLFHNML_02537	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
NHLFHNML_02538	1.83e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
NHLFHNML_02539	1.65e-288	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
NHLFHNML_02540	2.11e-152	yqfA	-	-	S	-	-	-	UPF0365 protein
NHLFHNML_02541	9.45e-85	-	-	-	-	-	-	-	-
NHLFHNML_02542	1e-62	yqfC	-	-	S	-	-	-	sporulation protein YqfC
NHLFHNML_02543	7.45e-278	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
NHLFHNML_02544	2.65e-220	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
NHLFHNML_02545	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
NHLFHNML_02546	1.88e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHLFHNML_02547	1.82e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
NHLFHNML_02548	9.11e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHLFHNML_02549	5.78e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHLFHNML_02550	2.53e-25	-	-	-	S	-	-	-	YqzL-like protein
NHLFHNML_02551	1.88e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
NHLFHNML_02553	4.79e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
NHLFHNML_02554	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
NHLFHNML_02555	5.23e-144	ccpN	-	-	K	-	-	-	CBS domain
NHLFHNML_02556	1.01e-183	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NHLFHNML_02557	7.46e-101	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
NHLFHNML_02558	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHLFHNML_02559	1.45e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHLFHNML_02560	6.91e-84	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
NHLFHNML_02561	2.63e-151	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
NHLFHNML_02562	1.48e-250	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHLFHNML_02563	3.02e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NHLFHNML_02564	5.53e-110	-	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
NHLFHNML_02565	2.17e-88	yqfQ	-	-	S	-	-	-	YqfQ-like protein
NHLFHNML_02566	9.18e-317	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHLFHNML_02567	2.64e-210	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NHLFHNML_02569	6.55e-273	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NHLFHNML_02570	3.27e-168	-	-	-	M	-	-	-	Transglycosylase SLT domain
NHLFHNML_02571	3.99e-183	zurA	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHLFHNML_02572	2.12e-179	zurM	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHLFHNML_02573	1.06e-99	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NHLFHNML_02574	4.23e-49	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
NHLFHNML_02576	1e-138	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
NHLFHNML_02577	1.97e-85	yqfX	-	-	S	-	-	-	membrane
NHLFHNML_02578	5.02e-255	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NHLFHNML_02579	8.72e-71	fimV	-	-	NU	ko:K08086,ko:K15845	ko05120,map05120	ko00000,ko00001	translation initiation factor activity
NHLFHNML_02580	6.32e-230	-	-	-	EGP	ko:K08221	-	ko00000,ko02000	Sugar (and other) transporter
NHLFHNML_02581	3.64e-193	ypuA	-	-	S	-	-	-	Secreted protein
NHLFHNML_02582	1.09e-146	-	-	-	O	-	-	-	NfeD-like C-terminal, partner-binding
NHLFHNML_02583	2.56e-248	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_02584	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
NHLFHNML_02590	4.56e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
NHLFHNML_02591	8.36e-295	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
NHLFHNML_02593	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
NHLFHNML_02594	9.89e-110	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
NHLFHNML_02595	6.87e-93	-	-	-	L	-	-	-	transposase activity
NHLFHNML_02596	9.67e-99	-	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHLFHNML_02597	7.46e-79	-	-	-	-	-	-	-	-
NHLFHNML_02598	5.85e-158	-	-	-	G	-	-	-	PFAM Glycoside hydrolase 15-related
NHLFHNML_02599	6.04e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
NHLFHNML_02600	7.02e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHLFHNML_02601	8.93e-180	-	-	-	S	-	-	-	Integral membrane protein DUF92
NHLFHNML_02602	3.31e-238	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHLFHNML_02603	6.17e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
NHLFHNML_02605	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
NHLFHNML_02606	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Bacillus/Clostridium GerA spore germination protein
NHLFHNML_02607	7.09e-88	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
NHLFHNML_02608	2.14e-105	-	-	-	-	-	-	-	-
NHLFHNML_02609	1.37e-10	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02610	5.13e-222	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
NHLFHNML_02611	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
NHLFHNML_02612	1.63e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHLFHNML_02613	3.67e-37	-	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
NHLFHNML_02614	2.03e-179	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NHLFHNML_02615	6.71e-265	thiO	1.4.3.19	-	E	ko:K03153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
NHLFHNML_02616	4.95e-180	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
NHLFHNML_02617	6.28e-124	-	-	-	-	-	-	-	-
NHLFHNML_02618	2.61e-237	yqgV	-	-	S	-	-	-	Thiamine-binding protein
NHLFHNML_02619	1.23e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHLFHNML_02620	3.32e-119	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
NHLFHNML_02621	1.05e-171	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
NHLFHNML_02622	4.16e-42	-	-	-	-	-	-	-	-
NHLFHNML_02623	3.54e-67	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_02624	2.58e-41	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
NHLFHNML_02625	7.35e-249	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHLFHNML_02626	3.46e-171	potC3	-	-	P	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02627	1.26e-178	-	-	-	E	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1176 ABC-type spermidine putrescine transport system, permease component I
NHLFHNML_02628	3.33e-213	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
NHLFHNML_02629	7.08e-250	-	-	-	E	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0687 Spermidine putrescine-binding periplasmic protein
NHLFHNML_02630	1.49e-74	-	-	-	-	-	-	-	-
NHLFHNML_02631	1.63e-63	-	-	-	-	-	-	-	-
NHLFHNML_02633	5.72e-207	XK27_03180	-	-	T	-	-	-	Belongs to the universal stress protein A family
NHLFHNML_02634	2.19e-180	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NHLFHNML_02635	4.4e-219	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
NHLFHNML_02636	0.0	fruC	2.7.1.202	-	G	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
NHLFHNML_02637	9.17e-100	fruD	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHLFHNML_02638	1.7e-200	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
NHLFHNML_02639	2.46e-114	-	-	-	-	-	-	-	-
NHLFHNML_02640	1.04e-110	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
NHLFHNML_02642	1.26e-10	tlp	-	-	S	ko:K06434	-	ko00000	spore protein
NHLFHNML_02643	1.1e-84	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Chalcone and stilbene synthases, N-terminal domain
NHLFHNML_02644	1e-147	ycfA	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02645	2.5e-245	ybhR	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
NHLFHNML_02646	9.01e-180	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
NHLFHNML_02647	1.2e-111	-	-	-	M	ko:K01993	-	ko00000	PFAM secretion protein HlyD family protein
NHLFHNML_02649	9.08e-260	thrCA	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NHLFHNML_02650	8.1e-187	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
NHLFHNML_02651	4.73e-303	-	-	-	KT	-	-	-	transcriptional regulatory protein
NHLFHNML_02652	0.0	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
NHLFHNML_02653	0.0	-	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
NHLFHNML_02654	7.21e-300	-	-	-	S	ko:K12940	-	ko00000,ko01002	Peptidase dimerisation domain
NHLFHNML_02655	4.05e-88	-	-	-	S	ko:K09957	-	ko00000	Putative glycolipid-binding
NHLFHNML_02656	1.82e-41	-	-	-	C	-	-	-	4Fe-4S binding domain
NHLFHNML_02657	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1450)
NHLFHNML_02658	9.49e-143	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, C-terminal domain
NHLFHNML_02659	1.44e-146	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02660	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
NHLFHNML_02661	5.24e-188	-	-	-	S	-	-	-	Glycosyl transferase family 2
NHLFHNML_02662	3.77e-248	-	-	-	M	-	-	-	Glycosyl transferases group 1
NHLFHNML_02663	3.26e-70	-	-	-	-	-	-	-	-
NHLFHNML_02664	1.28e-297	-	-	-	M	-	-	-	-O-antigen
NHLFHNML_02665	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHLFHNML_02666	1.16e-88	-	-	-	-	-	-	-	-
NHLFHNML_02667	7.15e-178	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
NHLFHNML_02668	1.49e-234	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NHLFHNML_02669	1.67e-223	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_02675	2.03e-268	-	-	-	UW	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
NHLFHNML_02679	4.86e-124	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHLFHNML_02680	7.37e-138	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
NHLFHNML_02681	8.56e-217	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHLFHNML_02682	3.34e-268	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_02683	5.12e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHLFHNML_02684	6.12e-190	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHLFHNML_02685	2.01e-113	dinB	-	-	S	-	-	-	DinB family
NHLFHNML_02686	5.27e-207	yobV	-	-	K	-	-	-	WYL domain
NHLFHNML_02687	5.82e-130	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
NHLFHNML_02688	1.67e-161	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHLFHNML_02689	1.77e-235	-	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHLFHNML_02691	3.12e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHLFHNML_02692	7.52e-263	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_02693	3.77e-52	-	-	-	-	-	-	-	-
NHLFHNML_02694	6.45e-12	-	-	-	-	-	-	-	-
NHLFHNML_02695	1.42e-143	yrzF	-	-	KLT	-	-	-	serine threonine protein kinase
NHLFHNML_02696	2.08e-112	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02697	1.15e-179	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
NHLFHNML_02698	1.33e-140	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
NHLFHNML_02699	4.69e-28	-	-	-	K	ko:K07729,ko:K20388	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
NHLFHNML_02702	6.89e-171	-	-	-	-	-	-	-	-
NHLFHNML_02703	2.21e-157	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_02704	1.24e-81	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
NHLFHNML_02706	1.1e-156	-	-	-	-	-	-	-	-
NHLFHNML_02707	3.74e-204	-	-	-	S	-	-	-	NYN domain
NHLFHNML_02708	8.83e-69	-	-	-	K	-	-	-	sequence-specific DNA binding
NHLFHNML_02709	2.95e-29	-	-	-	K	-	-	-	sequence-specific DNA binding
NHLFHNML_02710	0.0	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
NHLFHNML_02711	2.98e-315	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_02712	2.42e-206	-	-	-	G	ko:K02025,ko:K17238	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02713	1.39e-200	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02714	9.03e-256	-	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHLFHNML_02715	1.79e-131	-	-	-	-	-	-	-	-
NHLFHNML_02717	3.84e-233	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
NHLFHNML_02718	6.8e-224	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
NHLFHNML_02719	1.15e-206	lplC7	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
NHLFHNML_02720	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_02721	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	invertase
NHLFHNML_02722	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NHLFHNML_02723	9.95e-165	fabG9	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_02724	7.15e-280	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
NHLFHNML_02725	2.24e-37	-	-	-	-	-	-	-	-
NHLFHNML_02726	6.86e-126	pncA	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
NHLFHNML_02727	6.94e-146	ymaB	-	-	S	-	-	-	MutT family
NHLFHNML_02728	3.1e-246	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHLFHNML_02729	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHLFHNML_02730	4.03e-83	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
NHLFHNML_02731	2.74e-167	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
NHLFHNML_02732	5.17e-249	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHLFHNML_02733	0.0	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NHLFHNML_02734	3.35e-292	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NHLFHNML_02735	7.68e-173	-	-	-	I	-	-	-	CDP-alcohol phosphatidyltransferase
NHLFHNML_02736	7.06e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
NHLFHNML_02737	0.0	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHLFHNML_02738	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
NHLFHNML_02739	1.4e-206	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
NHLFHNML_02740	2.94e-31	-	-	-	-	-	-	-	-
NHLFHNML_02742	1.77e-261	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
NHLFHNML_02743	2.8e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
NHLFHNML_02744	1.32e-223	yhaX	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHLFHNML_02746	2.44e-65	-	-	-	-	-	-	-	-
NHLFHNML_02747	2.7e-159	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_02748	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_02749	4.85e-231	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
NHLFHNML_02750	1.14e-57	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
NHLFHNML_02751	2.97e-211	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHLFHNML_02752	1.23e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
NHLFHNML_02753	7.14e-133	-	-	-	S	-	-	-	Protein conserved in bacteria
NHLFHNML_02754	1.67e-140	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
NHLFHNML_02755	2.39e-64	yhaH	-	-	D	-	-	-	gas vesicle protein
NHLFHNML_02756	1.58e-261	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHLFHNML_02757	1.5e-96	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHLFHNML_02758	8.06e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
NHLFHNML_02759	2.61e-280	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_02760	1.23e-162	ecsC	-	-	S	-	-	-	EcsC protein family
NHLFHNML_02761	1.85e-155	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
NHLFHNML_02762	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHLFHNML_02763	2.21e-254	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NHLFHNML_02764	1.9e-229	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
NHLFHNML_02765	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NHLFHNML_02767	1.75e-129	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
NHLFHNML_02768	5.62e-292	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHLFHNML_02769	3.91e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
NHLFHNML_02770	3.72e-205	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
NHLFHNML_02771	9.2e-114	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
NHLFHNML_02772	8.13e-263	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NHLFHNML_02773	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
NHLFHNML_02774	2.01e-184	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
NHLFHNML_02775	3.87e-262	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NHLFHNML_02776	2.02e-222	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
NHLFHNML_02777	4.74e-25	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHLFHNML_02778	5.31e-82	-	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	cytochrome c oxidase subunit II
NHLFHNML_02779	2.61e-112	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
NHLFHNML_02780	1.58e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHLFHNML_02781	2.6e-233	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHLFHNML_02782	1.03e-37	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
NHLFHNML_02783	1.78e-240	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHLFHNML_02784	1.07e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHLFHNML_02785	1.58e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
NHLFHNML_02786	7.78e-76	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
NHLFHNML_02787	3.82e-94	-	-	-	S	-	-	-	membrane
NHLFHNML_02788	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHLFHNML_02789	9.5e-30	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
NHLFHNML_02790	1.5e-294	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHLFHNML_02791	1.1e-191	secF	-	-	U	ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHLFHNML_02792	5.69e-50	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
NHLFHNML_02793	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
NHLFHNML_02794	1.64e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHLFHNML_02795	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHLFHNML_02796	1.26e-95	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHLFHNML_02797	5.25e-234	-	-	-	K	-	-	-	LacI family transcriptional regulator
NHLFHNML_02798	4.35e-183	thuA	-	-	G	-	-	-	Trehalose utilisation
NHLFHNML_02799	1.94e-246	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_02800	1.35e-255	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
NHLFHNML_02802	6.5e-306	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
NHLFHNML_02803	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NHLFHNML_02804	5.22e-274	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
NHLFHNML_02805	5.89e-66	-	-	-	-	-	-	-	-
NHLFHNML_02806	3.37e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
NHLFHNML_02807	1.43e-175	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NHLFHNML_02808	7.73e-139	rsfA	-	-	S	ko:K06314	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_02809	3.14e-294	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NHLFHNML_02810	8.4e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_02811	4.23e-268	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
NHLFHNML_02812	1.05e-275	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHLFHNML_02813	5.69e-81	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
NHLFHNML_02814	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHLFHNML_02815	1.14e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02816	1.11e-41	yrzR	-	-	-	-	-	-	-
NHLFHNML_02817	3.8e-234	yrrI	-	-	S	-	-	-	AI-2E family transporter
NHLFHNML_02818	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHLFHNML_02819	1.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
NHLFHNML_02820	1.28e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHLFHNML_02821	2.04e-43	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
NHLFHNML_02822	2.35e-266	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHLFHNML_02823	3.15e-146	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
NHLFHNML_02824	4.67e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
NHLFHNML_02825	2.58e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHLFHNML_02826	6.64e-17	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
NHLFHNML_02827	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
NHLFHNML_02828	2.91e-191	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NHLFHNML_02829	2.39e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHLFHNML_02831	1.79e-101	-	-	-	-	-	-	-	-
NHLFHNML_02832	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
NHLFHNML_02833	1.96e-188	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLFHNML_02834	1.43e-181	-	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
NHLFHNML_02835	3.7e-204	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
NHLFHNML_02836	9.56e-194	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_02837	1.35e-136	arpR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_02838	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Starch/carbohydrate-binding module (family 53)
NHLFHNML_02839	7.24e-71	-	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHLFHNML_02840	4.16e-134	XK27_06885	-	-	L	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHLFHNML_02841	5.5e-238	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
NHLFHNML_02842	0.0	-	-	-	S	-	-	-	Membrane
NHLFHNML_02843	5.49e-282	hipO3	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
NHLFHNML_02844	3.82e-208	ybaS	-	-	S	-	-	-	Na -dependent transporter
NHLFHNML_02845	1.27e-159	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHLFHNML_02846	2.71e-35	-	-	-	-	-	-	-	-
NHLFHNML_02848	9.47e-70	-	-	-	-	-	-	-	-
NHLFHNML_02849	2.25e-244	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02850	1.71e-104	-	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
NHLFHNML_02851	4.22e-244	oppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_02852	1.49e-189	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_02853	4.99e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_02854	1.44e-201	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
NHLFHNML_02855	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NHLFHNML_02856	5.07e-130	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NHLFHNML_02857	2.5e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
NHLFHNML_02858	1.02e-256	degS	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NHLFHNML_02859	4.63e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHLFHNML_02860	4.62e-189	degV	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02861	1.11e-307	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHLFHNML_02862	1.43e-160	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
NHLFHNML_02863	4.48e-98	yvyF	-	-	S	-	-	-	flagellar protein
NHLFHNML_02864	3.56e-52	-	-	-	N	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Anti-sigma-28 factor, FlgM
NHLFHNML_02865	2.18e-07	yvyG	-	-	NOU	-	-	-	Flagellar biosynthesis protein FlgN
NHLFHNML_02866	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
NHLFHNML_02867	3.43e-239	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
NHLFHNML_02868	7.62e-97	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NHLFHNML_02869	2.29e-44	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NHLFHNML_02870	1.25e-63	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
NHLFHNML_02871	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NHLFHNML_02872	3.64e-86	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
NHLFHNML_02874	3.97e-175	-	-	-	-	-	-	-	-
NHLFHNML_02875	4.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	cold-shock protein
NHLFHNML_02876	6.07e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHLFHNML_02877	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHLFHNML_02878	1.02e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHLFHNML_02879	5.34e-188	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NHLFHNML_02880	2.48e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
NHLFHNML_02881	1.27e-193	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHLFHNML_02882	3.87e-163	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	peptidase
NHLFHNML_02883	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
NHLFHNML_02884	3.27e-258	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHLFHNML_02885	3.73e-216	yoaV3	-	-	EG	-	-	-	EamA-like transporter family
NHLFHNML_02886	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHLFHNML_02887	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHLFHNML_02888	1.29e-200	yvlB	-	-	S	-	-	-	Putative adhesin
NHLFHNML_02889	7.33e-16	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
NHLFHNML_02890	2.08e-63	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
NHLFHNML_02891	2.18e-218	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHLFHNML_02892	8.3e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHLFHNML_02893	2.78e-204	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
NHLFHNML_02894	2.32e-151	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NHLFHNML_02895	1.43e-105	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
NHLFHNML_02896	6.37e-278	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHLFHNML_02897	3.41e-144	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHLFHNML_02898	3e-290	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHLFHNML_02899	3.1e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
NHLFHNML_02900	1.92e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHLFHNML_02901	3.01e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHLFHNML_02902	3.5e-170	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHLFHNML_02903	1.57e-141	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
NHLFHNML_02904	2.6e-117	-	-	-	K	-	-	-	FR47-like protein
NHLFHNML_02905	8.84e-138	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_02906	3.42e-156	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHLFHNML_02907	6.21e-304	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
NHLFHNML_02908	2.1e-247	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
NHLFHNML_02909	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHLFHNML_02910	4.29e-116	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Nudix hydrolase
NHLFHNML_02911	4.57e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
NHLFHNML_02912	3e-225	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
NHLFHNML_02913	1.97e-228	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
NHLFHNML_02914	4.57e-51	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
NHLFHNML_02915	2.76e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NHLFHNML_02916	3.91e-215	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHLFHNML_02917	2.12e-138	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
NHLFHNML_02918	9.01e-272	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHLFHNML_02919	8.04e-72	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
NHLFHNML_02920	1.04e-288	-	-	-	E	-	-	-	Peptidase dimerisation domain
NHLFHNML_02921	3.09e-90	-	-	-	EGP	-	-	-	the major facilitator superfamily
NHLFHNML_02922	9e-56	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
NHLFHNML_02923	2.98e-18	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
NHLFHNML_02924	6.73e-133	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHLFHNML_02926	2.81e-296	sigL	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NHLFHNML_02927	3.02e-53	XAC3035	-	-	O	ko:K06191	-	ko00000	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NHLFHNML_02929	7.17e-258	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
NHLFHNML_02930	2.48e-229	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHLFHNML_02931	4.9e-239	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHLFHNML_02932	5.42e-275	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
NHLFHNML_02933	3.78e-169	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHLFHNML_02934	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
NHLFHNML_02935	9.59e-305	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHLFHNML_02936	1.93e-151	-	-	-	K	-	-	-	FCD
NHLFHNML_02937	6.52e-218	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
NHLFHNML_02938	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_02939	1.25e-282	-	4.2.1.158	-	M	ko:K20022	-	ko00000,ko01000	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
NHLFHNML_02940	6.75e-220	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
NHLFHNML_02941	1.17e-75	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
NHLFHNML_02942	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
NHLFHNML_02943	2.63e-99	yclD	-	-	-	-	-	-	-
NHLFHNML_02944	1.94e-37	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
NHLFHNML_02945	3.52e-223	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHLFHNML_02946	1.06e-176	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	COG1647 Esterase lipase
NHLFHNML_02947	1.24e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
NHLFHNML_02948	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHLFHNML_02949	1e-78	-	-	-	S	ko:K15977	-	ko00000	DoxX
NHLFHNML_02950	1.31e-103	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NHLFHNML_02952	4.7e-79	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHLFHNML_02953	1.14e-309	-	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_02954	1.12e-306	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHLFHNML_02958	8.63e-09	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
NHLFHNML_02959	5.08e-107	ssuE	1.5.1.38, 1.5.1.45	-	S	ko:K00299,ko:K16902	ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
NHLFHNML_02960	2.61e-214	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_02961	6.22e-266	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
NHLFHNML_02962	2.18e-170	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHLFHNML_02963	3.72e-158	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
NHLFHNML_02964	3.79e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NHLFHNML_02965	6.16e-200	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
NHLFHNML_02966	2.06e-177	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
NHLFHNML_02967	2.29e-274	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
NHLFHNML_02968	1.89e-234	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
NHLFHNML_02969	2.08e-144	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
NHLFHNML_02970	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
NHLFHNML_02971	7.09e-178	cbiX	4.99.1.3	-	C	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	CbiX
NHLFHNML_02972	1.58e-127	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
NHLFHNML_02973	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NHLFHNML_02974	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NHLFHNML_02975	1.22e-20	-	-	-	-	-	-	-	-
NHLFHNML_02976	2.12e-194	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
NHLFHNML_02977	2.84e-77	-	-	-	K	-	-	-	GntR family transcriptional regulator
NHLFHNML_02978	9.66e-271	yraM	-	-	S	-	-	-	PrpF protein
NHLFHNML_02979	5.33e-88	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
NHLFHNML_02980	0.0	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctA family
NHLFHNML_02981	2.52e-263	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
NHLFHNML_02982	1.53e-212	yraN	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_02983	2.43e-243	icd	1.1.1.41, 1.1.1.42, 1.1.1.85	-	CE	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
NHLFHNML_02984	0.0	-	-	-	C	ko:K13796	-	ko00000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
NHLFHNML_02985	1.91e-236	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
NHLFHNML_02986	1.12e-267	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
NHLFHNML_02987	1.14e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHLFHNML_02988	3.61e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NHLFHNML_02989	1.38e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_02990	1.55e-233	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
NHLFHNML_02991	1.1e-30	-	-	-	-	-	-	-	-
NHLFHNML_02992	6.32e-27	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NHLFHNML_02993	4.62e-289	cstA	-	-	T	-	-	-	Carbon starvation protein
NHLFHNML_02994	2.49e-248	ycgA	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
NHLFHNML_02995	2.49e-107	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NHLFHNML_02996	2.76e-162	-	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
NHLFHNML_02997	1.42e-203	-	-	-	P	-	-	-	Arsenic resistance protein
NHLFHNML_02998	4.94e-115	-	-	-	-	-	-	-	-
NHLFHNML_02999	1.36e-155	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NHLFHNML_03000	9.97e-59	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03001	1.14e-65	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03002	2.66e-306	ywbA	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHLFHNML_03003	4.1e-308	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHLFHNML_03004	2.13e-171	celCD	2.7.1.196, 2.7.1.205, 3.5.1.105	-	G	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
NHLFHNML_03005	2.91e-177	ybgA	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NHLFHNML_03006	0.0	chiA	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycoside Hydrolase Family 18
NHLFHNML_03007	6.78e-56	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
NHLFHNML_03008	7.98e-63	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
NHLFHNML_03009	5.99e-286	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
NHLFHNML_03010	8.43e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHLFHNML_03011	2.25e-302	kynU	3.7.1.3	-	E	ko:K01556	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
NHLFHNML_03012	4.84e-144	kynB	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
NHLFHNML_03013	3.02e-197	kynA	1.13.11.11	-	E	ko:K00453	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
NHLFHNML_03014	8.29e-255	-	-	-	E	ko:K06296	-	ko00000,ko02000	Spore germination protein
NHLFHNML_03016	6.22e-267	gerAC1	-	-	S	ko:K06297	-	ko00000	spore germination
NHLFHNML_03017	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
NHLFHNML_03018	3.94e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
NHLFHNML_03019	6.68e-300	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
NHLFHNML_03020	4.19e-238	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
NHLFHNML_03021	6.02e-280	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
NHLFHNML_03022	7.76e-195	araQ5	-	-	P	ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
NHLFHNML_03023	2.42e-208	cebF	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
NHLFHNML_03024	8.16e-291	lacE3	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
NHLFHNML_03027	9.78e-317	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
NHLFHNML_03028	2.06e-159	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHLFHNML_03029	8.17e-244	-	-	-	G	-	-	-	Acyltransferase family
NHLFHNML_03030	5.45e-205	-	-	-	P	-	-	-	YhfZ C-terminal domain
NHLFHNML_03031	2.33e-74	-	-	-	S	-	-	-	PRD domain
NHLFHNML_03032	4e-76	-	-	-	S	-	-	-	Protein of unknown function DUF2620
NHLFHNML_03033	9.85e-283	-	-	-	S	-	-	-	Protein of unknown function
NHLFHNML_03034	3.37e-220	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
NHLFHNML_03035	6.17e-261	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
NHLFHNML_03036	4.12e-275	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
NHLFHNML_03037	3.76e-288	-	-	-	G	-	-	-	Metalloenzyme superfamily
NHLFHNML_03038	0.0	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
NHLFHNML_03039	0.0	hscC	-	-	O	ko:K04045	-	ko00000,ko03110	Hsp70 protein
NHLFHNML_03040	1.89e-181	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_03041	1.61e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
NHLFHNML_03042	8.17e-114	-	-	-	-	-	-	-	-
NHLFHNML_03043	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_03044	1.56e-252	pamO	-	-	P	ko:K07222	-	ko00000	Flavin-binding monooxygenase-like
NHLFHNML_03045	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03046	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
NHLFHNML_03047	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NHLFHNML_03048	4.85e-193	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NHLFHNML_03049	1.79e-117	-	-	-	S	-	-	-	MepB protein
NHLFHNML_03050	1.52e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_03051	3.08e-164	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_03052	1.81e-80	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_03053	2.98e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
NHLFHNML_03054	7.25e-145	-	-	-	-	-	-	-	-
NHLFHNML_03055	4.42e-249	yhfE	-	-	G	-	-	-	peptidase M42
NHLFHNML_03056	5.28e-105	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
NHLFHNML_03057	2.47e-125	yhzB	-	-	S	-	-	-	B3/4 domain
NHLFHNML_03058	4.83e-277	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHLFHNML_03059	2.23e-119	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHLFHNML_03060	6.92e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_03061	9.22e-213	yhbB	-	-	S	-	-	-	Putative amidase domain
NHLFHNML_03062	1.69e-112	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHLFHNML_03063	2.08e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
NHLFHNML_03064	2.27e-69	-	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
NHLFHNML_03065	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
NHLFHNML_03066	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
NHLFHNML_03067	5.21e-111	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHLFHNML_03068	4.26e-131	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
NHLFHNML_03069	4.66e-177	cysA1	-	-	S	-	-	-	AAA domain
NHLFHNML_03070	4.51e-281	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
NHLFHNML_03073	1.05e-189	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_03074	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
NHLFHNML_03075	6.26e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
NHLFHNML_03076	6.07e-189	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
NHLFHNML_03078	2.91e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF664)
NHLFHNML_03079	0.0	-	-	-	G	ko:K10297	-	ko00000,ko04121	Right handed beta helix region
NHLFHNML_03080	3.19e-205	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_03081	0.0	-	-	-	E	ko:K03307	-	ko00000	Sodium:solute symporter family
NHLFHNML_03082	2.21e-164	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
NHLFHNML_03083	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
NHLFHNML_03085	3.27e-169	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
NHLFHNML_03086	1.91e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHLFHNML_03087	1.44e-171	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHLFHNML_03088	2.48e-164	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
NHLFHNML_03089	2.3e-278	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
NHLFHNML_03090	8.39e-144	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
NHLFHNML_03091	8.67e-171	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NHLFHNML_03092	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NHLFHNML_03093	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHLFHNML_03094	4.12e-116	sfsA	-	-	S	ko:K06206	-	ko00000	Sugar fermentation stimulation protein
NHLFHNML_03095	0.0	-	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
NHLFHNML_03096	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
NHLFHNML_03097	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
NHLFHNML_03098	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NHLFHNML_03099	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NHLFHNML_03100	1.01e-292	avtA	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHLFHNML_03101	1.37e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
NHLFHNML_03102	3.52e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
NHLFHNML_03103	1.97e-275	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
NHLFHNML_03104	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
NHLFHNML_03105	3.93e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
NHLFHNML_03106	1.59e-171	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
NHLFHNML_03107	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHLFHNML_03109	2.79e-274	-	-	-	-	-	-	-	-
NHLFHNML_03110	8.53e-102	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
NHLFHNML_03111	8.44e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_03112	1.11e-204	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
NHLFHNML_03113	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03114	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
NHLFHNML_03115	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
NHLFHNML_03116	5.24e-296	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHLFHNML_03117	2.18e-304	alsT	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
NHLFHNML_03118	2.39e-121	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NHLFHNML_03119	0.0	glpD	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NHLFHNML_03120	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHLFHNML_03121	7.12e-293	kinB3	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_03122	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
NHLFHNML_03123	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
NHLFHNML_03124	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NHLFHNML_03125	1.21e-216	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
NHLFHNML_03126	2.99e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NHLFHNML_03127	1.42e-174	phnE	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHLFHNML_03128	2.12e-183	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
NHLFHNML_03129	1.09e-180	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHLFHNML_03130	7.66e-308	-	-	-	V	-	-	-	MatE
NHLFHNML_03131	4.2e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_03132	1.08e-207	pepI	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha/beta hydrolase family
NHLFHNML_03133	8.08e-206	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_03134	1.14e-232	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_03135	0.0	hbpA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NHLFHNML_03136	8.75e-236	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_03137	5.46e-233	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_03138	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
NHLFHNML_03139	7.69e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
NHLFHNML_03140	4.34e-131	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_03141	3.51e-291	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
NHLFHNML_03142	2.46e-224	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	transport system, periplasmic component
NHLFHNML_03143	8.1e-218	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHLFHNML_03144	4.58e-177	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	transport system, ATPase component
NHLFHNML_03145	6.07e-228	-	-	-	-	-	-	-	-
NHLFHNML_03146	2.21e-253	cysA	3.6.3.25	-	P	ko:K02045	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NHLFHNML_03147	2.72e-172	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG4208 ABC-type sulfate transport system, permease component
NHLFHNML_03148	2.4e-172	cysT	-	-	O	ko:K02046	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0555 ABC-type sulfate transport system, permease component
NHLFHNML_03149	4.61e-251	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG1613 ABC-type sulfate transport system, periplasmic component
NHLFHNML_03150	7.39e-103	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHLFHNML_03151	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
NHLFHNML_03152	3.12e-98	dld	1.1.2.4, 1.1.3.15	-	C	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
NHLFHNML_03153	2.33e-212	dld	1.1.2.4, 1.1.3.15	-	C	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
NHLFHNML_03154	4.87e-198	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
NHLFHNML_03155	1.41e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHLFHNML_03156	1.34e-199	-	-	-	K	-	-	-	LysR substrate binding domain
NHLFHNML_03157	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NHLFHNML_03158	2.51e-261	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
NHLFHNML_03159	7.25e-83	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_03160	8.06e-123	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHLFHNML_03161	5.51e-193	malG	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03162	8.01e-215	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03163	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_03164	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
NHLFHNML_03165	4.98e-218	yisR1	3.2.1.23	-	K	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	AraC-like ligand binding domain
NHLFHNML_03166	7.9e-153	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_03167	1.58e-161	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_03168	2.15e-160	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_03169	2.14e-155	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
NHLFHNML_03170	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
NHLFHNML_03171	9.42e-95	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHLFHNML_03172	1.23e-96	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
NHLFHNML_03173	6.8e-135	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
NHLFHNML_03174	0.0	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHLFHNML_03175	2.43e-121	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
NHLFHNML_03176	4.15e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03177	3.61e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1569)
NHLFHNML_03178	3.17e-74	-	-	-	-	-	-	-	-
NHLFHNML_03179	1.11e-147	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHLFHNML_03180	7.1e-260	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
NHLFHNML_03182	4.97e-219	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
NHLFHNML_03183	1.67e-95	yjbI	-	-	S	ko:K06886	-	ko00000	COG2346 Truncated hemoglobins
NHLFHNML_03184	1.68e-135	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHLFHNML_03185	1.72e-122	yjbK	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03186	3.08e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
NHLFHNML_03187	1.02e-142	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
NHLFHNML_03188	7.48e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHLFHNML_03189	7.23e-208	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
NHLFHNML_03190	3.37e-176	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
NHLFHNML_03191	2e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF1360)
NHLFHNML_03192	1.34e-177	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
NHLFHNML_03193	1.85e-152	-	-	-	-	-	-	-	-
NHLFHNML_03194	1.7e-174	-	-	-	-	-	-	-	-
NHLFHNML_03196	6.94e-07	-	-	-	-	-	-	-	-
NHLFHNML_03197	1.77e-94	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
NHLFHNML_03198	1.12e-74	-	-	-	-	-	-	-	-
NHLFHNML_03199	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NHLFHNML_03200	3.34e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHLFHNML_03201	7.69e-232	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
NHLFHNML_03210	3.58e-55	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
NHLFHNML_03211	3.92e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
NHLFHNML_03212	3.58e-92	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
NHLFHNML_03214	2.01e-102	-	-	-	-	-	-	-	-
NHLFHNML_03217	2.65e-48	B4168_0554	-	-	S	-	-	-	Protein of unknown function (DUF2626)
NHLFHNML_03218	7.25e-153	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
NHLFHNML_03220	8.12e-196	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
NHLFHNML_03221	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHLFHNML_03222	2.23e-258	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
NHLFHNML_03223	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHLFHNML_03224	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHLFHNML_03225	1.34e-81	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
NHLFHNML_03226	2.06e-195	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NHLFHNML_03227	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
NHLFHNML_03228	1.4e-201	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NHLFHNML_03229	1.43e-250	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
NHLFHNML_03230	1.09e-99	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NHLFHNML_03231	9.09e-208	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
NHLFHNML_03232	3.09e-73	-	-	-	-	-	-	-	-
NHLFHNML_03233	4.24e-114	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
NHLFHNML_03234	3.62e-247	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
NHLFHNML_03235	7.96e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHLFHNML_03236	8.98e-122	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHLFHNML_03237	2.02e-63	-	-	-	S	-	-	-	YfzA-like protein
NHLFHNML_03238	2.71e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
NHLFHNML_03239	2.08e-211	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
NHLFHNML_03240	1.63e-105	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
NHLFHNML_03241	1.98e-40	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
NHLFHNML_03242	6.3e-54	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
NHLFHNML_03243	1.32e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
NHLFHNML_03244	6.05e-116	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
NHLFHNML_03245	2.88e-144	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
NHLFHNML_03246	1.41e-115	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
NHLFHNML_03247	3.08e-74	-	-	-	-	-	-	-	-
NHLFHNML_03248	2.63e-98	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHLFHNML_03249	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHLFHNML_03250	8.13e-85	yqhY	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03251	3.22e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHLFHNML_03252	1.04e-270	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHLFHNML_03253	2.03e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHLFHNML_03254	4.28e-197	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
NHLFHNML_03255	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHLFHNML_03256	6.11e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
NHLFHNML_03257	2.64e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
NHLFHNML_03258	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
NHLFHNML_03259	1.71e-300	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
NHLFHNML_03260	4.46e-183	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NHLFHNML_03261	6.24e-140	-	-	-	M	-	-	-	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHLFHNML_03262	5.51e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
NHLFHNML_03263	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
NHLFHNML_03264	8.44e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
NHLFHNML_03265	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHLFHNML_03266	4.89e-238	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHLFHNML_03267	2.22e-231	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHLFHNML_03268	5.09e-283	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHLFHNML_03269	2.39e-98	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
NHLFHNML_03270	5.74e-46	-	-	-	-	-	-	-	-
NHLFHNML_03271	8.38e-183	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
NHLFHNML_03272	8e-130	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
NHLFHNML_03273	6.68e-96	gerD	-	-	S	ko:K06294	-	ko00000	Spore gernimation protein
NHLFHNML_03274	3.18e-119	-	-	-	K	-	-	-	transcriptional regulator, RpiR family
NHLFHNML_03275	4.89e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
NHLFHNML_03276	3.88e-91	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
NHLFHNML_03277	2.03e-221	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHLFHNML_03278	1.67e-40	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PFAM Phosphotransferase system, lactose cellobiose-specific IIB subunit
NHLFHNML_03279	1.34e-95	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NHLFHNML_03280	2.04e-28	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03281	4.55e-31	-	-	-	K	-	-	-	MarR family transcriptional regulator
NHLFHNML_03282	3.05e-209	-	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NHLFHNML_03283	2.18e-245	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NHLFHNML_03284	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03285	8.39e-196	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
NHLFHNML_03286	3.02e-171	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NHLFHNML_03287	4.26e-104	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
NHLFHNML_03288	1.05e-90	ykkB	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_03290	1.26e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_03291	1.54e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
NHLFHNML_03292	4.45e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
NHLFHNML_03293	2.77e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHLFHNML_03294	6.89e-186	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHLFHNML_03295	2.94e-168	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHLFHNML_03296	1.73e-185	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHLFHNML_03297	7.78e-202	cbiO	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHLFHNML_03298	1.49e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
NHLFHNML_03299	4.06e-216	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHLFHNML_03300	4.05e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHLFHNML_03301	8.92e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHLFHNML_03302	5.99e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
NHLFHNML_03303	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHLFHNML_03304	1.1e-180	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NHLFHNML_03305	7.76e-152	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHLFHNML_03306	1.39e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHLFHNML_03307	9.26e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NHLFHNML_03308	7.06e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
NHLFHNML_03309	1.59e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHLFHNML_03310	8.96e-79	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHLFHNML_03311	1.83e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHLFHNML_03312	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHLFHNML_03313	2.21e-121	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHLFHNML_03314	7.7e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHLFHNML_03315	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHLFHNML_03316	2.17e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHLFHNML_03317	5.12e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
NHLFHNML_03318	3.79e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHLFHNML_03319	1.76e-154	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHLFHNML_03320	8.5e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHLFHNML_03321	1.53e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHLFHNML_03322	5.09e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHLFHNML_03323	1.38e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHLFHNML_03324	2.22e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
NHLFHNML_03325	9.49e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHLFHNML_03326	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
NHLFHNML_03327	6.72e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHLFHNML_03328	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHLFHNML_03329	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHLFHNML_03330	4.33e-95	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHLFHNML_03331	3.72e-47	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
NHLFHNML_03332	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHLFHNML_03333	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHLFHNML_03334	2.91e-148	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
NHLFHNML_03335	1.27e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHLFHNML_03336	8.48e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHLFHNML_03337	4.64e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHLFHNML_03338	1.19e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHLFHNML_03339	1.83e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
NHLFHNML_03340	2.37e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHLFHNML_03341	9.77e-152	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
NHLFHNML_03342	5.28e-111	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
NHLFHNML_03343	3.82e-184	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHLFHNML_03344	8.52e-91	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHLFHNML_03345	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
NHLFHNML_03346	1.98e-156	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
NHLFHNML_03347	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHLFHNML_03348	1.49e-107	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NHLFHNML_03349	1.13e-150	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NHLFHNML_03350	5.61e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
NHLFHNML_03351	4.09e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NHLFHNML_03352	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHLFHNML_03353	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
NHLFHNML_03354	1.88e-250	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NHLFHNML_03355	1.2e-121	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
NHLFHNML_03356	4.79e-95	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
NHLFHNML_03357	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
NHLFHNML_03358	2.17e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHLFHNML_03359	4.18e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHLFHNML_03360	4.26e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHLFHNML_03361	1.68e-188	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHLFHNML_03362	1.82e-190	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
NHLFHNML_03363	3.61e-138	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
NHLFHNML_03364	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHLFHNML_03365	2.28e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NHLFHNML_03366	1.63e-201	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHLFHNML_03367	3.69e-183	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NHLFHNML_03368	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHLFHNML_03369	9.01e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
NHLFHNML_03370	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHLFHNML_03371	6.67e-223	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
NHLFHNML_03372	2.19e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
NHLFHNML_03373	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
NHLFHNML_03374	3.42e-283	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
NHLFHNML_03376	8.65e-92	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
NHLFHNML_03377	2.87e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
NHLFHNML_03378	4.43e-93	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
NHLFHNML_03379	9.26e-69	yabP	-	-	S	-	-	-	Sporulation protein YabP
NHLFHNML_03380	3.17e-131	-	-	-	S	-	-	-	SNARE associated Golgi protein
NHLFHNML_03381	8.86e-250	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
NHLFHNML_03382	1.47e-110	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHLFHNML_03383	1.37e-222	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHLFHNML_03384	1.49e-146	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
NHLFHNML_03385	1.21e-35	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHLFHNML_03386	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NHLFHNML_03387	7.13e-298	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHLFHNML_03388	8.06e-115	-	-	-	S	-	-	-	Yip1 domain
NHLFHNML_03389	1.43e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHLFHNML_03390	4.55e-134	-	-	-	S	-	-	-	Yip1 domain
NHLFHNML_03391	1.89e-122	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
NHLFHNML_03392	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHLFHNML_03393	7.35e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
NHLFHNML_03394	8.63e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHLFHNML_03395	1.79e-137	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NHLFHNML_03396	7.02e-218	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHLFHNML_03397	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHLFHNML_03399	2.26e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NHLFHNML_03400	4.06e-81	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
NHLFHNML_03401	1.56e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
NHLFHNML_03402	5.3e-208	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHLFHNML_03403	1.8e-34	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
NHLFHNML_03404	4.02e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03405	2.53e-208	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
NHLFHNML_03406	1.39e-200	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHLFHNML_03407	5.18e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHLFHNML_03408	6.3e-268	yabE	-	-	T	-	-	-	protein conserved in bacteria
NHLFHNML_03409	3.03e-183	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
NHLFHNML_03410	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
NHLFHNML_03411	1.68e-146	-	-	-	T	-	-	-	protein histidine kinase activity
NHLFHNML_03412	0.0	-	-	-	S	-	-	-	ABC transporter
NHLFHNML_03414	5.54e-236	pelB	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Amb_all
NHLFHNML_03415	1.34e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
NHLFHNML_03416	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHLFHNML_03417	0.0	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
NHLFHNML_03418	5.58e-221	-	-	-	S	-	-	-	NurA
NHLFHNML_03419	3.04e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
NHLFHNML_03420	1.29e-199	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHLFHNML_03421	9.86e-54	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
NHLFHNML_03422	1.28e-172	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
NHLFHNML_03423	1.21e-59	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
NHLFHNML_03424	3.66e-188	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
NHLFHNML_03425	3.03e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
NHLFHNML_03426	9.77e-71	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03427	6.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHLFHNML_03428	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
NHLFHNML_03430	4.76e-221	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
NHLFHNML_03431	9.24e-138	yfhC	-	-	C	-	-	-	nitroreductase
NHLFHNML_03432	2.52e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
NHLFHNML_03433	7.02e-81	-	-	-	S	-	-	-	Bacteriophage holin family
NHLFHNML_03435	0.0	-	-	-	L	-	-	-	Phage minor structural protein
NHLFHNML_03436	1.5e-169	-	-	-	S	-	-	-	Phage tail protein
NHLFHNML_03437	7.17e-184	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
NHLFHNML_03438	6.77e-100	-	-	-	-	-	-	-	-
NHLFHNML_03439	3.67e-93	-	-	-	-	-	-	-	-
NHLFHNML_03440	1.75e-69	-	-	-	S	-	-	-	Short C-terminal domain
NHLFHNML_03441	1.31e-268	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
NHLFHNML_03442	1.28e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
NHLFHNML_03443	8.29e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
NHLFHNML_03444	0.0	malK	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
NHLFHNML_03445	2.91e-94	-	-	-	M	-	-	-	ArpU family transcriptional regulator
NHLFHNML_03446	6.89e-192	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NHLFHNML_03447	1.09e-151	-	-	-	E	ko:K02029,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03448	7.32e-144	-	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03449	1.33e-191	tcyA_1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
NHLFHNML_03450	5.88e-173	-	-	-	-	-	-	-	-
NHLFHNML_03451	2.48e-193	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
NHLFHNML_03452	2.22e-231	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
NHLFHNML_03453	2.07e-90	-	-	-	S	-	-	-	GtrA-like protein
NHLFHNML_03454	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
NHLFHNML_03455	2.57e-10	-	-	-	-	-	-	-	-
NHLFHNML_03456	1.75e-10	-	-	-	-	-	-	-	-
NHLFHNML_03457	5.72e-110	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
NHLFHNML_03458	1.08e-171	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NHLFHNML_03459	5.65e-136	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
NHLFHNML_03460	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
NHLFHNML_03461	2.71e-177	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
NHLFHNML_03462	2.38e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NHLFHNML_03463	2.79e-97	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
NHLFHNML_03464	1.58e-113	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
NHLFHNML_03465	1.35e-299	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
NHLFHNML_03466	1.34e-233	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NHLFHNML_03467	3.23e-108	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
NHLFHNML_03468	1.59e-124	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NHLFHNML_03469	7.31e-114	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NHLFHNML_03470	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
NHLFHNML_03471	2.12e-183	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHLFHNML_03472	3.39e-156	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NHLFHNML_03473	7.91e-164	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
NHLFHNML_03474	1.25e-282	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
NHLFHNML_03475	5.5e-56	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
NHLFHNML_03476	2.27e-93	-	2.7.1.194	-	GT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NHLFHNML_03477	0.0	-	-	-	G	-	-	-	Mga helix-turn-helix domain
NHLFHNML_03478	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHLFHNML_03479	7.46e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHLFHNML_03480	7.8e-152	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
NHLFHNML_03481	4.84e-256	gldA	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
NHLFHNML_03482	1.09e-185	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
NHLFHNML_03483	3.22e-142	metP_2	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
NHLFHNML_03484	5.64e-232	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHLFHNML_03485	1.16e-178	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHLFHNML_03486	7.3e-34	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHLFHNML_03487	3.56e-145	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHLFHNML_03488	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
NHLFHNML_03489	1.96e-229	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHLFHNML_03490	7.1e-111	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHLFHNML_03491	7.66e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
NHLFHNML_03492	2.14e-105	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
NHLFHNML_03493	1.55e-228	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHLFHNML_03496	8.25e-271	-	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NHLFHNML_03497	7.27e-73	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHLFHNML_03498	6.37e-78	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHLFHNML_03499	8.89e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
NHLFHNML_03500	1.43e-233	-	-	-	V	-	-	-	Domain of unknown function (DUF3471)
NHLFHNML_03501	2.23e-86	puuR	-	-	K	-	-	-	sequence-specific DNA binding
NHLFHNML_03502	2.99e-89	puuR	-	-	K	-	-	-	sequence-specific DNA binding
NHLFHNML_03504	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
NHLFHNML_03505	1.16e-148	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHLFHNML_03506	2.05e-202	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
NHLFHNML_03508	1.29e-111	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NHLFHNML_03509	9.46e-67	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
NHLFHNML_03510	2.9e-26	-	-	-	-	-	-	-	-
NHLFHNML_03511	7.48e-299	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHLFHNML_03512	5.49e-124	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
NHLFHNML_03513	1.16e-214	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHLFHNML_03514	2.23e-71	yusE	-	-	CO	-	-	-	cell redox homeostasis
NHLFHNML_03515	3.64e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
NHLFHNML_03516	6.98e-95	-	-	-	CO	-	-	-	Thioredoxin-like
NHLFHNML_03517	4e-175	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
NHLFHNML_03518	7.53e-195	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
NHLFHNML_03519	4.52e-41	-	-	-	-	-	-	-	-
NHLFHNML_03520	7.1e-111	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
NHLFHNML_03521	8.27e-311	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
NHLFHNML_03522	2.09e-244	-	-	-	S	-	-	-	Protein of unknown function (DUF2777)
NHLFHNML_03523	1.34e-209	-	-	-	-	-	-	-	-
NHLFHNML_03524	1.12e-196	telA	-	-	P	-	-	-	Belongs to the TelA family
NHLFHNML_03526	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
NHLFHNML_03527	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NHLFHNML_03528	1.16e-146	ypjP	-	-	S	-	-	-	YpjP-like protein
NHLFHNML_03529	8.96e-51	-	-	-	-	-	-	-	-
NHLFHNML_03531	1.8e-79	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
NHLFHNML_03532	5e-199	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHLFHNML_03533	2.9e-05	-	-	-	S	ko:K06376	-	ko00000	Spo0E like sporulation regulatory protein
NHLFHNML_03534	1.1e-108	-	-	-	-	-	-	-	-
NHLFHNML_03535	7.58e-188	ycsE	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHLFHNML_03536	1.31e-24	-	-	-	-	-	-	-	-
NHLFHNML_03537	5.03e-229	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
NHLFHNML_03538	5.9e-137	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
NHLFHNML_03539	2.07e-116	-	-	-	-	-	-	-	-
NHLFHNML_03540	5.46e-259	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
NHLFHNML_03541	2.3e-237	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
NHLFHNML_03542	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
NHLFHNML_03543	0.0	pepF	-	-	E	-	-	-	oligoendopeptidase F
NHLFHNML_03544	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NHLFHNML_03545	3.83e-276	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
NHLFHNML_03546	2.88e-07	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
NHLFHNML_03547	4.08e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
NHLFHNML_03548	1.53e-63	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHLFHNML_03549	1.73e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
NHLFHNML_03550	4.53e-50	-	-	-	-	-	-	-	-
NHLFHNML_03551	1.29e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
NHLFHNML_03552	1.87e-223	-	-	-	S	-	-	-	Oxidoreductase
NHLFHNML_03553	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
NHLFHNML_03554	2.86e-81	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
NHLFHNML_03555	8.13e-82	-	-	-	-	-	-	-	-
NHLFHNML_03556	1.35e-211	-	-	-	NT	-	-	-	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
NHLFHNML_03558	4.15e-258	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
NHLFHNML_03559	4.82e-255	-	-	-	E	-	-	-	Spore germination protein
NHLFHNML_03560	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
NHLFHNML_03561	6.31e-79	-	-	-	S	-	-	-	Src homology 3 domains
NHLFHNML_03562	3.09e-66	-	-	-	-	-	-	-	-
NHLFHNML_03563	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
NHLFHNML_03564	2.04e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
NHLFHNML_03566	6.45e-235	-	-	-	G	-	-	-	Transmembrane secretion effector
NHLFHNML_03567	5.89e-109	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
NHLFHNML_03568	1.96e-69	-	-	-	S	-	-	-	Belongs to the HesB IscA family
NHLFHNML_03569	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NHLFHNML_03570	1.75e-120	-	-	-	U	-	-	-	MarC family integral membrane protein
NHLFHNML_03571	3.79e-173	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_03572	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
NHLFHNML_03573	6.28e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
NHLFHNML_03574	1.18e-103	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
NHLFHNML_03575	6.47e-64	-	-	-	S	-	-	-	Cyclic-di-AMP receptor
NHLFHNML_03576	1.8e-220	ghrA	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHLFHNML_03577	4.67e-114	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
NHLFHNML_03578	5.63e-311	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
NHLFHNML_03579	1.92e-241	ygaE	-	-	S	-	-	-	Membrane
NHLFHNML_03580	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
NHLFHNML_03581	2.94e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
NHLFHNML_03582	1.43e-21	-	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
NHLFHNML_03583	9.29e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_03584	5.62e-27	yfhS	-	-	-	-	-	-	-
NHLFHNML_03585	2.23e-77	-	-	-	-	-	-	-	-
NHLFHNML_03586	2.34e-162	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_03587	5.47e-257	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
NHLFHNML_03588	2.33e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
NHLFHNML_03589	9.25e-30	-	-	-	S	-	-	-	YpzG-like protein
NHLFHNML_03590	8.82e-68	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
NHLFHNML_03591	1.03e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
NHLFHNML_03592	6.23e-213	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
NHLFHNML_03593	1.36e-65	-	-	-	-	-	-	-	-
NHLFHNML_03594	7.01e-244	mccF	-	-	V	-	-	-	LD-carboxypeptidase
NHLFHNML_03595	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHLFHNML_03596	1.32e-80	-	-	-	-	-	-	-	-
NHLFHNML_03597	1.84e-172	-	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NHLFHNML_03598	8.04e-236	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03599	3.78e-175	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_03600	2.96e-146	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Survival protein SurE
NHLFHNML_03601	1.14e-107	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLFHNML_03602	9.82e-92	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_03603	9.9e-209	-	-	-	O	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
NHLFHNML_03604	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NHLFHNML_03606	1.24e-187	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
NHLFHNML_03607	3.22e-181	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
NHLFHNML_03608	1.83e-313	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
NHLFHNML_03609	1.02e-146	-	-	-	G	ko:K15640	-	ko00000	Belongs to the phosphoglycerate mutase family
NHLFHNML_03610	2.79e-278	yfkA	-	-	S	-	-	-	YfkB-like domain
NHLFHNML_03611	1.97e-188	yfkD	-	-	S	-	-	-	YfkD-like protein
NHLFHNML_03614	1.21e-29	-	-	-	S	-	-	-	Fur-regulated basic protein B
NHLFHNML_03615	4.16e-314	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
NHLFHNML_03616	9.49e-240	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NHLFHNML_03617	1.33e-165	-	-	-	-	-	-	-	-
NHLFHNML_03618	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
NHLFHNML_03619	0.0	kat	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
NHLFHNML_03622	1.55e-308	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
NHLFHNML_03623	2.13e-311	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NHLFHNML_03624	5.77e-145	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Caulimovirus viroplasmin
NHLFHNML_03625	1.81e-54	-	-	-	-	-	-	-	-
NHLFHNML_03626	5.13e-61	-	-	-	K	-	-	-	SpoVT / AbrB like domain
NHLFHNML_03627	2.07e-75	-	-	-	-	-	-	-	-
NHLFHNML_03628	3.46e-302	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHLFHNML_03629	2.05e-231	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
NHLFHNML_03630	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NHLFHNML_03631	1.84e-208	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
NHLFHNML_03632	3.5e-171	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
NHLFHNML_03633	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHLFHNML_03634	5.93e-261	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NHLFHNML_03635	1.27e-109	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
NHLFHNML_03636	2.36e-156	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
NHLFHNML_03637	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
NHLFHNML_03638	2.61e-96	-	-	-	S	-	-	-	Protein of unknown function, DUF600
NHLFHNML_03639	5.61e-107	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
NHLFHNML_03640	2.87e-88	-	-	-	-	-	-	-	-
NHLFHNML_03641	8.64e-245	-	-	-	S	-	-	-	LXG domain of WXG superfamily
NHLFHNML_03642	1.4e-186	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
NHLFHNML_03643	7.73e-139	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
NHLFHNML_03644	8.65e-310	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
NHLFHNML_03645	1.64e-151	yhcQ	-	-	M	-	-	-	Spore coat protein
NHLFHNML_03646	6.91e-06	-	-	-	S	-	-	-	Sporulation inhibitor A
NHLFHNML_03647	6.55e-223	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
NHLFHNML_03648	1.55e-224	eutB	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
NHLFHNML_03649	9.58e-271	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
NHLFHNML_03650	2.23e-150	-	-	-	S	-	-	-	HTH domain
NHLFHNML_03651	8.12e-240	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Arginase family
NHLFHNML_03652	2.79e-162	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
NHLFHNML_03653	1.29e-256	-	-	-	T	-	-	-	Histidine kinase
NHLFHNML_03654	3.57e-209	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
NHLFHNML_03655	9.72e-156	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
NHLFHNML_03656	9.1e-141	ydfE	-	-	S	-	-	-	Flavin reductase like domain
NHLFHNML_03657	5.87e-182	-	1.1.1.140	-	C	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_03658	1.14e-71	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
NHLFHNML_03659	7.08e-225	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
NHLFHNML_03660	3.77e-127	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
NHLFHNML_03661	2.85e-98	srlR	-	-	K	-	-	-	Glucitol operon activator
NHLFHNML_03662	7.72e-221	-	-	-	K	-	-	-	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHLFHNML_03663	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
NHLFHNML_03664	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
NHLFHNML_03665	0.0	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_03666	2.36e-155	yteU	-	-	S	-	-	-	Integral membrane protein
NHLFHNML_03667	1.92e-101	-	-	-	G	-	-	-	carbohydrate transport
NHLFHNML_03668	2.31e-282	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NHLFHNML_03669	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
NHLFHNML_03670	1.3e-210	-	-	-	E	-	-	-	Abhydrolase family
NHLFHNML_03671	3.09e-188	ytcP3	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03672	4.85e-231	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
NHLFHNML_03673	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_03674	0.0	-	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_03675	1.29e-201	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_03676	1.17e-248	-	4.2.2.2	-	M	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectic acid lyase
NHLFHNML_03677	5.06e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_03678	3.25e-166	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
NHLFHNML_03679	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
NHLFHNML_03680	0.0	lplA3	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_03681	5.35e-216	lplC1	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03682	4.78e-223	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03683	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
NHLFHNML_03684	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_03685	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
NHLFHNML_03686	1.01e-257	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
NHLFHNML_03687	3e-226	nagC_1	-	-	GK	-	-	-	ROK family
NHLFHNML_03688	0.0	M1-1044	-	-	S	-	-	-	Belongs to the UPF0061 (SELO) family
NHLFHNML_03689	4.59e-96	-	-	-	S	-	-	-	DinB superfamily
NHLFHNML_03690	1.53e-209	-	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NHLFHNML_03691	1.34e-174	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
NHLFHNML_03692	5.54e-207	-	-	-	S	-	-	-	Alpha beta hydrolase
NHLFHNML_03694	6.54e-95	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	2'-deoxycytidine 5'-triphosphate deaminase (DCD)
NHLFHNML_03695	2.87e-186	-	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
NHLFHNML_03697	3.86e-202	ccpC	-	-	K	-	-	-	Transcriptional regulator
NHLFHNML_03698	3.19e-82	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
NHLFHNML_03699	4.61e-106	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHLFHNML_03700	2.81e-316	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHLFHNML_03701	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
NHLFHNML_03702	2.18e-138	spoVAEA	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
NHLFHNML_03703	5.03e-75	-	-	-	S	ko:K06407	-	ko00000	Pfam:SpoVA
NHLFHNML_03704	1.62e-232	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
NHLFHNML_03705	1.18e-103	-	-	-	S	ko:K06405	-	ko00000	Pfam:SpoVA
NHLFHNML_03706	7.67e-175	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHLFHNML_03707	7.62e-97	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NHLFHNML_03708	7.27e-73	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
NHLFHNML_03709	1.21e-268	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NHLFHNML_03710	1.42e-176	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NHLFHNML_03711	2.22e-108	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
NHLFHNML_03712	1.68e-69	-	-	-	-	-	-	-	-
NHLFHNML_03713	3.18e-29	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
NHLFHNML_03714	2.08e-302	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
NHLFHNML_03715	7.51e-154	-	-	-	J	-	-	-	translation release factor activity
NHLFHNML_03716	4.19e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
NHLFHNML_03717	7.13e-294	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
NHLFHNML_03718	3.88e-284	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHLFHNML_03719	5.76e-212	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
NHLFHNML_03720	8.77e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
NHLFHNML_03721	8.92e-111	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
NHLFHNML_03722	6.83e-140	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NHLFHNML_03723	2.38e-116	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
NHLFHNML_03725	1.6e-106	-	-	-	CO	-	-	-	Thioredoxin-like
NHLFHNML_03726	1.47e-179	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHLFHNML_03727	2.71e-186	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03728	2.2e-194	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03729	3.12e-255	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
NHLFHNML_03730	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Cache domain
NHLFHNML_03731	4.6e-291	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_03732	9.59e-268	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NHLFHNML_03733	1.04e-118	-	-	-	S	-	-	-	UPF0316 protein
NHLFHNML_03734	6.73e-107	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
NHLFHNML_03735	2.79e-125	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
NHLFHNML_03736	1.48e-69	ogt	-	-	L	ko:K07443	-	ko00000	Methyltransferase
NHLFHNML_03737	3.55e-106	-	-	-	V	-	-	-	COG4767 Glycopeptide antibiotics resistance protein
NHLFHNML_03738	1.84e-234	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
NHLFHNML_03739	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
NHLFHNML_03740	1.63e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHLFHNML_03741	1.26e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHLFHNML_03742	1.99e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHLFHNML_03743	4.13e-161	-	-	-	P	ko:K08714	-	ko00000,ko02000	Polycystin cation channel
NHLFHNML_03744	3.56e-314	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
NHLFHNML_03746	3.09e-66	-	-	-	-	-	-	-	-
NHLFHNML_03747	3.57e-62	tnrA	-	-	K	-	-	-	transcriptional
NHLFHNML_03748	1.31e-176	yibQ	-	-	S	ko:K09798	-	ko00000	protein conserved in bacteria
NHLFHNML_03749	0.0	apr	-	-	O	-	-	-	Belongs to the peptidase S8 family
NHLFHNML_03750	1.01e-55	-	-	-	-	-	-	-	-
NHLFHNML_03751	7.08e-96	ykuL	-	-	S	-	-	-	CBS domain
NHLFHNML_03752	4.89e-102	-	-	-	S	-	-	-	Pfam Polyketide cyclase dehydrase and lipid transport
NHLFHNML_03753	1.95e-89	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
NHLFHNML_03755	3.85e-121	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
NHLFHNML_03756	2.17e-246	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
NHLFHNML_03757	5.72e-90	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
NHLFHNML_03759	5.96e-122	yqjB	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03760	1.84e-214	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
NHLFHNML_03761	1.24e-213	-	-	-	F	-	-	-	GHKL domain
NHLFHNML_03762	1.5e-24	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease
NHLFHNML_03763	1.1e-82	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	permease
NHLFHNML_03764	3.22e-119	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHLFHNML_03765	1.22e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
NHLFHNML_03766	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHLFHNML_03767	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
NHLFHNML_03769	3.2e-235	-	-	-	S	-	-	-	Protein of unknown function (DUF3533)
NHLFHNML_03770	1.54e-172	-	-	-	S	-	-	-	SnoaL-like domain
NHLFHNML_03771	1.46e-119	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
NHLFHNML_03772	3.97e-60	-	-	-	K	-	-	-	ArsR family transcriptional regulator
NHLFHNML_03773	4.84e-252	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
NHLFHNML_03774	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
NHLFHNML_03775	8.69e-60	-	-	-	J	-	-	-	oxidation-reduction process
NHLFHNML_03776	8.63e-102	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
NHLFHNML_03777	1.77e-218	-	-	-	S	-	-	-	thiolester hydrolase activity
NHLFHNML_03778	2.36e-294	-	3.3.2.9	-	S	ko:K01253	ko00980,ko04976,ko05204,map00980,map04976,map05204	ko00000,ko00001,ko01000,ko01002	Epoxide hydrolase
NHLFHNML_03780	4e-196	-	-	-	K	-	-	-	DNA-binding protein
NHLFHNML_03781	3.57e-170	dltE3	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
NHLFHNML_03782	1.31e-306	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHLFHNML_03783	1.06e-131	-	-	-	K	-	-	-	Bacterial transcriptional repressor C-terminal
NHLFHNML_03784	1.16e-45	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
NHLFHNML_03786	4.36e-40	-	-	-	E	-	-	-	lactoylglutathione lyase activity
NHLFHNML_03787	7.44e-113	-	-	-	F	-	-	-	uridine kinase
NHLFHNML_03788	9.38e-166	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_03789	0.0	pbpE	-	-	V	-	-	-	Beta-lactamase
NHLFHNML_03790	9.9e-57	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHLFHNML_03791	2.05e-167	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_03792	3.56e-160	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NHLFHNML_03793	2.21e-23	-	2.3.1.60	-	K	ko:K03395	-	br01600,ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
NHLFHNML_03794	3e-74	yvaF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_03795	2.3e-163	-	-	-	EGP	ko:K08167	-	ko00000,ko00002,ko01504,ko02000	PFAM major facilitator superfamily MFS_1
NHLFHNML_03796	1.51e-185	cypA	-	-	Q	-	-	-	Cytochrome P450
NHLFHNML_03797	6.65e-203	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_03798	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
NHLFHNML_03799	0.0	-	-	-	G	-	-	-	alpha-L-rhamnosidase
NHLFHNML_03800	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
NHLFHNML_03801	1.07e-266	-	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	amidohydrolase
NHLFHNML_03802	5.64e-54	-	-	-	S	-	-	-	PRD domain
NHLFHNML_03803	1.81e-77	-	-	-	S	-	-	-	Glycine-rich SFCGS
NHLFHNML_03804	4.13e-76	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
NHLFHNML_03805	5.42e-178	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
NHLFHNML_03806	8.24e-146	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
NHLFHNML_03807	1.82e-254	selA	2.9.1.1	-	E	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
NHLFHNML_03808	1.28e-165	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
NHLFHNML_03809	2.19e-88	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
NHLFHNML_03810	3.14e-228	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03811	3.24e-237	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
NHLFHNML_03812	4.24e-65	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
NHLFHNML_03813	5.46e-115	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
NHLFHNML_03814	5.04e-193	-	-	-	G	-	-	-	domain, Protein
NHLFHNML_03815	3.67e-123	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
NHLFHNML_03816	3.7e-234	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_03817	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHLFHNML_03818	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHLFHNML_03819	9.83e-12	yqbO1	-	-	S	-	-	-	Domain of unknown function (DUF370)
NHLFHNML_03820	4.47e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHLFHNML_03821	1.15e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
NHLFHNML_03822	3.45e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHLFHNML_03823	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHLFHNML_03824	3.58e-22	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
NHLFHNML_03825	2.54e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NHLFHNML_03826	8.72e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHLFHNML_03827	9.02e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
NHLFHNML_03828	4.9e-315	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHLFHNML_03829	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHLFHNML_03830	2.39e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NHLFHNML_03831	1.49e-191	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NHLFHNML_03832	3.38e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
NHLFHNML_03833	4.1e-192	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
NHLFHNML_03834	2.57e-272	-	-	-	E	-	-	-	Aminotransferase class-V
NHLFHNML_03835	2.82e-146	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
NHLFHNML_03836	1.18e-229	yyaD	-	-	S	-	-	-	Membrane
NHLFHNML_03837	1.19e-37	yyzM	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03838	1.98e-246	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHLFHNML_03839	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
NHLFHNML_03840	4.66e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHLFHNML_03841	4.32e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHLFHNML_03842	2.4e-185	yybS	-	-	S	-	-	-	membrane
NHLFHNML_03843	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
NHLFHNML_03844	2.34e-87	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
NHLFHNML_03845	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
NHLFHNML_03846	1.94e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHLFHNML_03852	2.06e-170	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_03853	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_03854	7.39e-309	yycH	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03855	7.43e-205	yycI	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_03856	3.29e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NHLFHNML_03857	9.93e-268	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHLFHNML_03858	1.43e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHLFHNML_03859	3.9e-152	spoIVCA	-	-	L	ko:K06400	-	ko00000	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NHLFHNML_03860	5.68e-41	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_03861	2.01e-152	-	-	-	-	-	-	-	-
NHLFHNML_03862	8.97e-96	-	-	-	V	-	-	-	type I restriction modification DNA specificity domain
NHLFHNML_03863	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
NHLFHNML_03864	7.7e-229	XK27_09655	-	-	S	-	-	-	Virulence protein RhuM family
NHLFHNML_03865	2.42e-132	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
NHLFHNML_03866	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
NHLFHNML_03867	3.14e-147	-	-	-	S	ko:K07043	-	ko00000	WLM domain
NHLFHNML_03868	7.94e-150	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NHLFHNML_03869	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_03870	9.03e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
NHLFHNML_03871	1.78e-100	scdA	-	-	D	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
NHLFHNML_03872	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHLFHNML_03873	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
NHLFHNML_03874	7.28e-146	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
NHLFHNML_03875	3.15e-161	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	nitrate reductase, gamma subunit
NHLFHNML_03876	1.19e-107	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	phosphoenolpyruvate-protein phosphotransferase activity
NHLFHNML_03877	5.82e-250	nreB	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NHLFHNML_03878	3.81e-142	nreC	-	-	T	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHLFHNML_03879	0.0	narK	-	-	P	ko:K02575,ko:K10850	ko00910,ko02020,map00910,map02020	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
NHLFHNML_03880	2.43e-157	-	-	-	S	-	-	-	YwiC-like protein
NHLFHNML_03881	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_03882	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_03883	1.3e-284	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
NHLFHNML_03884	1.42e-220	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03885	7.21e-204	ytcP1	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_03886	2.59e-51	-	-	-	-	-	-	-	-
NHLFHNML_03887	8.18e-128	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
NHLFHNML_03888	3.35e-140	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
NHLFHNML_03889	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
NHLFHNML_03890	1.66e-214	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_03891	8.57e-248	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
NHLFHNML_03892	5.9e-259	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
NHLFHNML_03893	1.21e-137	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHLFHNML_03894	2.1e-280	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
NHLFHNML_03895	2.16e-99	-	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
NHLFHNML_03896	1.85e-71	-	-	-	-	-	-	-	-
NHLFHNML_03897	8.17e-114	-	3.1.1.29	-	K	ko:K01056	-	ko00000,ko01000,ko03012	-acetyltransferase
NHLFHNML_03898	8.87e-307	-	-	-	EK	-	-	-	Alanine-glyoxylate amino-transferase
NHLFHNML_03899	5.3e-104	yvbK	-	-	K	-	-	-	acetyltransferase
NHLFHNML_03900	3.43e-187	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
NHLFHNML_03901	1.21e-104	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHLFHNML_03902	1.68e-257	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
NHLFHNML_03903	2.79e-236	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Sugar diacid utilization regulator
NHLFHNML_03904	2.66e-249	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
NHLFHNML_03905	3.95e-160	-	-	-	-	-	-	-	-
NHLFHNML_03906	1.24e-145	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHLFHNML_03907	5.48e-236	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NHLFHNML_03908	4.18e-196	hisJ3	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
NHLFHNML_03909	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NHLFHNML_03910	1.06e-122	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
NHLFHNML_03911	1.76e-165	-	-	-	-	ko:K06336	-	ko00000,ko01002	-
NHLFHNML_03912	1.19e-121	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
NHLFHNML_03913	2.62e-167	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHLFHNML_03914	4.06e-223	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NHLFHNML_03915	1.29e-297	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
NHLFHNML_03916	2.52e-135	cwlK	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
NHLFHNML_03917	2.69e-316	-	-	-	E	ko:K03294,ko:K14052	-	ko00000,ko02000	Amino acid permease
NHLFHNML_03918	6.97e-202	sseA	2.8.1.1, 2.8.1.2	-	P	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	ko00000,ko00001,ko01000	sulfurtransferase
NHLFHNML_03919	2.53e-282	yukF	-	-	QT	-	-	-	Transcriptional regulator
NHLFHNML_03920	1.31e-249	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
NHLFHNML_03921	7.67e-254	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
NHLFHNML_03922	5.77e-194	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
NHLFHNML_03923	5.9e-193	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
NHLFHNML_03924	6.65e-207	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_03925	1e-220	dppC	-	-	EP	ko:K16201	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_03926	1.57e-233	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_03927	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
NHLFHNML_03928	1.13e-221	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
NHLFHNML_03929	3.2e-211	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NHLFHNML_03930	1.89e-230	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_03931	2.4e-78	hxlR	-	-	K	-	-	-	transcriptional
NHLFHNML_03932	6e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
NHLFHNML_03933	1.77e-167	-	-	-	T	-	-	-	Universal stress protein family
NHLFHNML_03934	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHLFHNML_03935	5.43e-85	mnhB2	-	-	P	ko:K05566	-	ko00000,ko02000	antiporter activity
NHLFHNML_03936	1.85e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHLFHNML_03937	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHLFHNML_03938	8.09e-111	mnhE2	-	-	P	ko:K05569	-	ko00000,ko02000	Na+/H+ ion antiporter subunit
NHLFHNML_03939	2.23e-51	mnhF2	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHLFHNML_03940	2.2e-77	-	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
NHLFHNML_03941	2.62e-201	-	-	-	S	-	-	-	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NHLFHNML_03942	1.21e-246	-	-	-	G	-	-	-	Xylose isomerase
NHLFHNML_03943	3.47e-244	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
NHLFHNML_03944	1.56e-175	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
NHLFHNML_03945	5.18e-272	-	-	-	S	ko:K09927	-	ko00000	Winged helix DNA-binding domain
NHLFHNML_03946	8e-137	-	-	-	S	-	-	-	Integral membrane protein
NHLFHNML_03947	1.01e-62	-	-	-	-	-	-	-	-
NHLFHNML_03948	1.44e-177	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
NHLFHNML_03949	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NHLFHNML_03950	3.34e-131	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHLFHNML_03951	1.32e-170	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
NHLFHNML_03952	2.81e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHLFHNML_03953	1.7e-237	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
NHLFHNML_03954	4.05e-285	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHLFHNML_03955	4.38e-35	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NHLFHNML_03956	8.86e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
NHLFHNML_03957	2.86e-179	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
NHLFHNML_03958	2.21e-69	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
NHLFHNML_03959	5.84e-95	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NHLFHNML_03960	6.63e-234	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
NHLFHNML_03961	1.39e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
NHLFHNML_03962	6.56e-107	rsbW	2.7.11.1	-	T	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NHLFHNML_03963	1.49e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHLFHNML_03964	5.95e-147	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
NHLFHNML_03965	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
NHLFHNML_03966	3.43e-13	-	-	-	-	-	-	-	-
NHLFHNML_03967	1.4e-114	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
NHLFHNML_03974	5.7e-95	-	-	-	S	-	-	-	SnoaL-like polyketide cyclase
NHLFHNML_03975	1.72e-304	-	-	-	S	ko:K12941	-	ko00000,ko01002	amidohydrolase
NHLFHNML_03976	9.49e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
NHLFHNML_03977	9.19e-99	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
NHLFHNML_03978	1.31e-259	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
NHLFHNML_03979	1.46e-287	yhaA1	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHLFHNML_03980	2.85e-89	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
NHLFHNML_03981	5.13e-209	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
NHLFHNML_03982	0.0	ytgP	-	-	S	ko:K03328,ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHLFHNML_03983	9.29e-253	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
NHLFHNML_03984	4.05e-266	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
NHLFHNML_03985	7.12e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
NHLFHNML_03986	4.69e-43	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
NHLFHNML_03987	3.05e-92	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NHLFHNML_03988	2.22e-208	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
NHLFHNML_03989	7.71e-138	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_03990	1.99e-205	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
NHLFHNML_03991	1.16e-213	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
NHLFHNML_03992	2.29e-131	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NHLFHNML_03993	3.74e-80	-	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NHLFHNML_03994	5.9e-144	cidB	-	-	M	-	-	-	effector of murein hydrolase
NHLFHNML_03995	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
NHLFHNML_03996	1.15e-262	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NHLFHNML_03997	1.55e-225	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHLFHNML_03998	1.42e-244	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHLFHNML_03999	1.21e-270	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHLFHNML_04000	7.62e-68	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
NHLFHNML_04001	2.27e-161	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHLFHNML_04002	1.04e-209	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NHLFHNML_04003	9.14e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
NHLFHNML_04005	2.52e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHLFHNML_04006	5.27e-64	ytzB	-	-	-	-	-	-	-
NHLFHNML_04007	4.52e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
NHLFHNML_04008	6.99e-112	yjjX	-	-	F	-	-	-	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
NHLFHNML_04009	7.88e-100	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
NHLFHNML_04010	1.06e-183	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
NHLFHNML_04011	1.15e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
NHLFHNML_04012	5.66e-187	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
NHLFHNML_04013	6.41e-134	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHLFHNML_04014	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
NHLFHNML_04015	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
NHLFHNML_04016	1.68e-84	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHLFHNML_04017	1.14e-27	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
NHLFHNML_04018	1.18e-251	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NHLFHNML_04019	5.04e-237	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
NHLFHNML_04020	2.28e-293	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
NHLFHNML_04021	1.55e-142	acuB	-	-	S	ko:K04767	-	ko00000	Acetoin utilization protein AcuB
NHLFHNML_04022	2.34e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NHLFHNML_04023	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHLFHNML_04024	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHLFHNML_04025	1.1e-232	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
NHLFHNML_04026	8.39e-75	-	-	-	S	-	-	-	Regulatory protein YrvL
NHLFHNML_04027	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K06931,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
NHLFHNML_04028	0.0	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
NHLFHNML_04029	1.51e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHLFHNML_04030	3.13e-62	-	-	-	-	-	-	-	-
NHLFHNML_04031	5.26e-123	p20	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHLFHNML_04032	2.68e-161	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
NHLFHNML_04033	1.08e-188	adcA	-	-	P	ko:K09815,ko:K09818	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
NHLFHNML_04034	1.08e-83	yxjI	-	-	S	-	-	-	LURP-one-related
NHLFHNML_04035	1.26e-184	gspA	-	-	M	-	-	-	Glycosyl transferase family 8
NHLFHNML_04036	2.41e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NHLFHNML_04037	1.16e-271	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_04038	6.26e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
NHLFHNML_04039	1.38e-137	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
NHLFHNML_04040	5.71e-245	-	-	-	T	-	-	-	Signal transduction histidine kinase
NHLFHNML_04041	2.7e-118	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
NHLFHNML_04042	5.45e-146	-	-	-	S	-	-	-	AAA domain
NHLFHNML_04043	1.23e-160	-	-	-	L	-	-	-	DNA alkylation repair enzyme
NHLFHNML_04044	3e-290	serS3	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHLFHNML_04045	2.8e-28	-	-	-	T	-	-	-	Histidine kinase
NHLFHNML_04046	5.87e-185	-	-	-	S	-	-	-	Alpha beta hydrolase
NHLFHNML_04047	5.75e-90	-	-	-	K	-	-	-	Helix-turn-helix domain
NHLFHNML_04049	1.87e-182	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
NHLFHNML_04050	1.25e-76	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_04051	1.54e-81	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
NHLFHNML_04052	1.04e-76	ydzF	-	-	K	-	-	-	HxlR-like helix-turn-helix
NHLFHNML_04053	7.76e-179	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase agmatinase formimionoglutamate hydrolase, arginase family
NHLFHNML_04054	3.6e-147	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_04055	1.18e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
NHLFHNML_04056	7.89e-142	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
NHLFHNML_04057	6.08e-151	-	-	-	S	-	-	-	3-demethylubiquinone-9 3-methyltransferase
NHLFHNML_04058	1.63e-139	mrsE3	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_04059	9.24e-136	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
NHLFHNML_04060	3.28e-150	ccmA3	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacitracin ABC transporter ATP-binding protein
NHLFHNML_04061	3e-192	yvrG	-	-	T	-	-	-	Histidine kinase
NHLFHNML_04062	2.13e-149	yvrH	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_04064	4.16e-216	yjiA	-	-	S	-	-	-	Cobalamin biosynthesis protein CobW
NHLFHNML_04065	1.5e-232	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NHLFHNML_04066	0.0	psaA3	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Zinc-uptake complex component A periplasmic
NHLFHNML_04067	2.49e-166	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHLFHNML_04068	1.77e-158	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
NHLFHNML_04069	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_04070	3.33e-211	-	4.1.2.28, 4.3.3.7	-	EM	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
NHLFHNML_04071	5.32e-209	-	4.2.1.141	-	S	ko:K14259	ko00040,map00040	ko00000,ko00001,ko01000	Fumarylacetoacetate (FAA) hydrolase family
NHLFHNML_04072	1.06e-179	-	-	-	K	ko:K19333	-	ko00000,ko03000	helix_turn_helix isocitrate lyase regulation
NHLFHNML_04073	0.0	-	4.2.1.82	-	EG	ko:K22396	ko00040,map00040	ko00000,ko00001,ko01000	Dehydratase family
NHLFHNML_04074	1.28e-312	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
NHLFHNML_04075	3.78e-41	-	-	-	K	-	-	-	MerR family transcriptional regulator
NHLFHNML_04076	2.11e-172	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
NHLFHNML_04077	1.05e-123	-	-	-	-	-	-	-	-
NHLFHNML_04078	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHLFHNML_04079	5.49e-102	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
NHLFHNML_04080	1.26e-213	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHLFHNML_04081	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHLFHNML_04082	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHLFHNML_04083	3.39e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHLFHNML_04084	2.89e-115	yizA	-	-	S	-	-	-	DinB family
NHLFHNML_04085	4.95e-221	-	-	-	-	-	-	-	-
NHLFHNML_04087	7.13e-207	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHLFHNML_04088	1.52e-241	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
NHLFHNML_04089	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_04090	1.29e-260	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
NHLFHNML_04091	2.82e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
NHLFHNML_04092	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHLFHNML_04093	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
NHLFHNML_04094	8.05e-166	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NHLFHNML_04096	1.02e-194	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
NHLFHNML_04097	1.45e-216	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_04098	6.69e-224	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHLFHNML_04100	5.18e-34	mepA	-	-	V	-	-	-	MATE efflux family protein
NHLFHNML_04101	1.91e-186	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
NHLFHNML_04102	8.33e-187	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NHLFHNML_04103	8.28e-221	-	-	-	K	-	-	-	AraC-like ligand binding domain
NHLFHNML_04104	7.12e-314	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
NHLFHNML_04105	3.52e-195	M1-465	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_04106	1.29e-202	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_04107	1.48e-64	esxA	-	-	S	-	-	-	Belongs to the WXG100 family
NHLFHNML_04108	7.61e-52	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
NHLFHNML_04109	4.04e-273	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
NHLFHNML_04110	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NHLFHNML_04111	0.0	yueB	-	-	S	-	-	-	domain protein
NHLFHNML_04112	2.51e-93	-	-	-	S	-	-	-	Family of unknown function (DUF5383)
NHLFHNML_04113	4.22e-60	-	-	-	-	-	-	-	-
NHLFHNML_04114	2.34e-63	-	-	-	-	-	-	-	-
NHLFHNML_04115	1.95e-97	-	-	-	-	-	-	-	-
NHLFHNML_04116	6.77e-312	-	-	-	S	-	-	-	nuclease activity
NHLFHNML_04118	1.82e-63	-	-	-	-	-	-	-	-
NHLFHNML_04121	4.53e-11	-	-	-	S	-	-	-	nuclease activity
NHLFHNML_04123	9.93e-115	-	-	-	-	-	-	-	-
NHLFHNML_04124	0.000123	-	-	-	S	-	-	-	LXG domain of WXG superfamily
NHLFHNML_04126	2.06e-68	-	-	-	-	-	-	-	-
NHLFHNML_04130	2.46e-218	-	-	-	G	-	-	-	Glycoside hydrolase family 16
NHLFHNML_04134	7.99e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
NHLFHNML_04135	0.0	-	-	-	Q	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
NHLFHNML_04136	8.17e-114	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
NHLFHNML_04137	8.37e-98	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHLFHNML_04138	5.17e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
NHLFHNML_04139	3.74e-186	yaaC	-	-	S	-	-	-	YaaC-like Protein
NHLFHNML_04140	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHLFHNML_04141	1.62e-304	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
NHLFHNML_04142	3.68e-279	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHLFHNML_04143	7.85e-187	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHLFHNML_04144	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
NHLFHNML_04145	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NHLFHNML_04146	2.77e-291	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
NHLFHNML_04147	9.32e-238	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
NHLFHNML_04148	2.99e-307	nhaC_2	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
NHLFHNML_04149	3.52e-297	-	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
NHLFHNML_04150	6.52e-290	-	2.5.1.48, 4.4.1.11	-	E	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
NHLFHNML_04151	1.03e-285	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
NHLFHNML_04152	7.29e-245	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
NHLFHNML_04153	0.0	gabD_2	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHLFHNML_04154	1.59e-79	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
NHLFHNML_04155	2.39e-184	glnH	-	-	ET	ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ligated ion channel L-glutamate- and glycine-binding site
NHLFHNML_04156	1.23e-141	glnP	-	-	E	ko:K02029,ko:K10037,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Polar amino acid ABC transporter, inner membrane subunit
NHLFHNML_04157	3.37e-162	-	3.6.3.21	-	E	ko:K02028,ko:K10038	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
NHLFHNML_04158	3.88e-242	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_04159	6.47e-245	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
NHLFHNML_04160	3.19e-214	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_04161	1.83e-203	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHLFHNML_04162	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
NHLFHNML_04163	0.0	M1-554	-	-	G	-	-	-	Endonuclease Exonuclease Phosphatase
NHLFHNML_04164	6.8e-18	-	-	-	S	-	-	-	Inner spore coat protein D
NHLFHNML_04165	8.16e-79	-	-	-	FJ	-	-	-	tRNA wobble adenosine to inosine editing
NHLFHNML_04166	3.54e-198	-	-	-	P	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
NHLFHNML_04167	1.34e-201	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
NHLFHNML_04168	2.38e-292	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
NHLFHNML_04169	9.11e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHLFHNML_04170	0.0	ltaS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
NHLFHNML_04171	8.82e-164	lacR	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
NHLFHNML_04172	8.22e-269	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHLFHNML_04173	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
NHLFHNML_04174	1.16e-213	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NHLFHNML_04176	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
NHLFHNML_04177	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
NHLFHNML_04178	7.01e-213	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
NHLFHNML_04179	1.07e-65	-	-	-	-	-	-	-	-
NHLFHNML_04180	1.37e-31	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
NHLFHNML_04181	1.97e-168	yvcP	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_04182	3.86e-239	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
NHLFHNML_04183	6.34e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_04184	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NHLFHNML_04186	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
NHLFHNML_04187	4.63e-197	-	-	-	S	-	-	-	CAAX amino terminal protease family protein
NHLFHNML_04188	1.67e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_04189	5.45e-112	yqeB	-	-	-	-	-	-	-
NHLFHNML_04190	2.22e-83	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
NHLFHNML_04191	1.68e-184	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
NHLFHNML_04192	8.94e-126	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHLFHNML_04193	2.67e-52	-	-	-	S	-	-	-	Helix-turn-helix domain
NHLFHNML_04194	2.2e-42	-	-	-	K	-	-	-	Sigma-70, region 4
NHLFHNML_04195	8.22e-41	-	-	-	K	-	-	-	Sigma-70, region 4
NHLFHNML_04196	1.55e-206	-	-	-	I	-	-	-	Acyltransferase family
NHLFHNML_04197	2.13e-44	-	-	-	-	-	-	-	-
NHLFHNML_04198	1.46e-150	-	-	-	S	-	-	-	Sap, sulfolipid-1-addressing protein
NHLFHNML_04199	2.24e-134	-	-	-	K	-	-	-	BetI-type transcriptional repressor, C-terminal
NHLFHNML_04200	1.58e-94	-	-	-	L	ko:K07487	-	ko00000	Transposase
NHLFHNML_04201	2.46e-139	-	-	-	L	ko:K07487	-	ko00000	PFAM transposase IS4 family protein
NHLFHNML_04203	5.8e-168	-	-	-	S	-	-	-	Alpha/beta hydrolase family
NHLFHNML_04205	3.36e-100	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
NHLFHNML_04206	3.73e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
NHLFHNML_04207	4.03e-239	pbpX	-	-	V	-	-	-	penicillin-binding protein
NHLFHNML_04208	1.21e-43	-	-	-	S	-	-	-	Predicted integral membrane protein (DUF2269)
NHLFHNML_04209	6.4e-179	blt5	-	-	EGP	-	-	-	of the major facilitator superfamily
NHLFHNML_04210	1.82e-186	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
NHLFHNML_04211	2.1e-199	yddH	-	-	M	-	-	-	Lysozyme-like
NHLFHNML_04212	1.25e-298	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
NHLFHNML_04213	0.0	-	-	-	S	-	-	-	AAA-like domain
NHLFHNML_04214	6.25e-17	-	-	-	KQ	-	-	-	Methyltransferase
NHLFHNML_04215	2.98e-32	-	-	-	KQ	-	-	-	MerR family transcriptional regulator
NHLFHNML_04216	1.72e-125	yrkC	-	-	G	-	-	-	Cupin domain
NHLFHNML_04217	1.74e-103	-	-	-	S	-	-	-	TraX protein
NHLFHNML_04218	2.3e-53	-	-	-	S	-	-	-	TraX protein
NHLFHNML_04219	5.32e-214	mviM3	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
NHLFHNML_04220	3.48e-40	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
NHLFHNML_04221	1.91e-98	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
NHLFHNML_04222	2.26e-65	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
NHLFHNML_04223	5.33e-86	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHLFHNML_04224	9.94e-71	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
NHLFHNML_04225	1.61e-277	ydfA	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NHLFHNML_04226	9.45e-99	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NHLFHNML_04228	3.22e-295	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
NHLFHNML_04229	6.33e-207	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
NHLFHNML_04230	4.42e-144	ydhC	-	-	K	-	-	-	FCD
NHLFHNML_04231	4.62e-252	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
NHLFHNML_04232	2.8e-85	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHLFHNML_04233	5.15e-141	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
NHLFHNML_04234	0.0	-	-	-	L	-	-	-	ABC transporter
NHLFHNML_04235	1.27e-95	-	-	-	K	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
NHLFHNML_04236	8.68e-74	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
NHLFHNML_04237	1.04e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
NHLFHNML_04238	8.09e-65	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
NHLFHNML_04239	2.28e-159	azlC	-	-	E	-	-	-	AzlC protein
NHLFHNML_04240	1.81e-94	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHLFHNML_04241	4.61e-93	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
NHLFHNML_04242	2.68e-67	-	-	-	GM	-	-	-	NmrA-like family
NHLFHNML_04243	5.29e-145	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
NHLFHNML_04244	7.96e-116	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
NHLFHNML_04245	7.09e-88	-	-	-	J	-	-	-	L-PSP family endoribonuclease
NHLFHNML_04246	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
NHLFHNML_04247	2.37e-10	-	-	-	-	-	-	-	-
NHLFHNML_04249	6.63e-231	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
NHLFHNML_04250	9.69e-128	-	-	-	CO	-	-	-	Thioredoxin
NHLFHNML_04251	4.23e-218	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
NHLFHNML_04252	2.38e-256	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NHLFHNML_04253	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
NHLFHNML_04254	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
NHLFHNML_04255	3.15e-281	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
NHLFHNML_04256	1.14e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
NHLFHNML_04257	6.28e-36	-	-	-	S	-	-	-	Helix-turn-helix domain
NHLFHNML_04258	3.81e-230	-	-	-	T	-	-	-	Histidine kinase-like ATPases
NHLFHNML_04259	1.4e-160	rrp1	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHLFHNML_04260	1.41e-174	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
NHLFHNML_04261	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
NHLFHNML_04262	3.65e-259	-	-	-	L	ko:K07487	-	ko00000	Transposase domain (DUF772)
NHLFHNML_04263	3.62e-50	-	-	-	-	-	-	-	-
NHLFHNML_04264	1.03e-29	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
NHLFHNML_04265	9.35e-161	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
NHLFHNML_04266	2.23e-260	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
NHLFHNML_04267	9.67e-253	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHLFHNML_04268	1.28e-227	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHLFHNML_04269	3.14e-191	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NHLFHNML_04270	1.64e-209	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NHLFHNML_04271	8.4e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NHLFHNML_04272	1.01e-223	-	-	-	S	-	-	-	Tetratricopeptide repeat
NHLFHNML_04273	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
NHLFHNML_04274	1.96e-311	mtaD	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
NHLFHNML_04276	8.74e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
NHLFHNML_04277	1.59e-104	ypmB	-	-	S	-	-	-	protein conserved in bacteria
NHLFHNML_04278	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
NHLFHNML_04279	1.14e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
NHLFHNML_04280	1.45e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHLFHNML_04282	1.57e-75	-	-	-	-	-	-	-	-
NHLFHNML_04284	1.24e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
NHLFHNML_04285	3.94e-41	-	-	-	-	-	-	-	-
NHLFHNML_04286	6.7e-62	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
NHLFHNML_04287	1.35e-38	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
NHLFHNML_04288	4.66e-128	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
NHLFHNML_04290	3.34e-244	-	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NHLFHNML_04291	9.3e-275	-	-	-	E	-	-	-	Peptidase family M28
NHLFHNML_04292	1.7e-134	yhfK	-	-	GM	-	-	-	NmrA-like family
NHLFHNML_04293	1.57e-227	ytvI	-	-	S	-	-	-	AI-2E family transporter
NHLFHNML_04294	2.69e-117	copC	-	-	S	ko:K07156	-	ko00000,ko02000	CopC domain
NHLFHNML_04296	3.35e-248	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
NHLFHNML_04297	1.62e-232	-	-	-	T	-	-	-	Metal dependent phosphohydrolases with conserved 'HD' motif.
NHLFHNML_04298	5.05e-186	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
NHLFHNML_04299	5.61e-115	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHLFHNML_04300	1.58e-281	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
NHLFHNML_04301	1.22e-270	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHLFHNML_04302	4.19e-50	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
NHLFHNML_04305	1.04e-106	-	-	-	-	-	-	-	-
NHLFHNML_04306	5.53e-159	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
NHLFHNML_04307	0.0	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
NHLFHNML_04308	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
NHLFHNML_04309	6.86e-172	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
NHLFHNML_04310	5.08e-72	-	-	-	-	-	-	-	-
NHLFHNML_04311	7.62e-120	-	-	-	S	-	-	-	DinB superfamily
NHLFHNML_04312	6.95e-45	-	-	-	-	-	-	-	-
NHLFHNML_04313	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
NHLFHNML_04314	2.74e-37	-	-	-	-	-	-	-	-
NHLFHNML_04315	2.35e-70	-	-	-	S	-	-	-	membrane
NHLFHNML_04316	1.58e-132	-	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
NHLFHNML_04317	1.6e-171	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
NHLFHNML_04318	2.13e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
NHLFHNML_04319	2.04e-174	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
NHLFHNML_04320	1.92e-197	yjaZ	-	-	O	-	-	-	Zn-dependent protease
NHLFHNML_04321	3.16e-180	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
NHLFHNML_04322	1.94e-15	-	-	-	-	-	-	-	-
NHLFHNML_04323	4.12e-228	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
NHLFHNML_04325	3.34e-132	-	-	-	CO	-	-	-	Redoxin
NHLFHNML_04326	1.76e-127	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
NHLFHNML_04327	2.48e-143	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
NHLFHNML_04328	1.34e-12	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
NHLFHNML_04329	6.91e-296	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
NHLFHNML_04330	6.86e-126	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHLFHNML_04332	2.03e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHLFHNML_04334	5.73e-23	-	-	-	-	-	-	-	-
NHLFHNML_04336	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NHLFHNML_04337	7.68e-172	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
NHLFHNML_04338	1.96e-310	glvA	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHLFHNML_04339	7.67e-162	-	-	-	K	ko:K11922	-	ko00000,ko03000	UTRA
NHLFHNML_04340	7.66e-136	-	-	-	S	-	-	-	CAAX protease self-immunity
NHLFHNML_04341	1.11e-230	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
NHLFHNML_04342	2.86e-210	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
NHLFHNML_04344	6.37e-189	-	-	-	S	-	-	-	Nucleotidyltransferase domain
NHLFHNML_04353	5.17e-36	-	-	-	-	-	-	-	-
NHLFHNML_04355	4.11e-123	-	-	-	-	-	-	-	-
NHLFHNML_04356	3.74e-206	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
NHLFHNML_04357	0.0	-	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NHLFHNML_04358	2.93e-201	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
NHLFHNML_04359	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
NHLFHNML_04361	8.34e-221	-	-	-	L	-	-	-	Endonuclease/Exonuclease/phosphatase family
NHLFHNML_04362	7.21e-101	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
NHLFHNML_04365	1.96e-110	-	2.7.1.190	-	S	ko:K17910	-	ko00000,ko01000,ko01504	Protein of unknown function (DUF1679)
NHLFHNML_04366	4.39e-149	-	-	-	O	-	-	-	Sap, sulfolipid-1-addressing protein
NHLFHNML_04367	5.18e-94	-	-	-	-	-	-	-	-
NHLFHNML_04368	7.39e-183	-	-	-	K	-	-	-	MerR family transcriptional regulator
NHLFHNML_04369	9.48e-204	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
NHLFHNML_04370	2.78e-241	-	-	-	M	-	-	-	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
NHLFHNML_04371	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
NHLFHNML_04372	9.71e-253	adhA	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
NHLFHNML_04373	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	Sigma-54 interaction domain
NHLFHNML_04374	0.0	cckA	2.7.13.3	-	T	ko:K02482	-	ko00000,ko01000,ko01001,ko02022	GAF domain
NHLFHNML_04375	3.81e-17	-	-	-	-	-	-	-	-
NHLFHNML_04376	1.18e-258	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	alcohol dehydrogenase
NHLFHNML_04378	6.95e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHLFHNML_04379	7.88e-131	clpP1	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHLFHNML_04380	1.57e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
NHLFHNML_04381	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHLFHNML_04382	4.53e-51	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHLFHNML_04383	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHLFHNML_04384	1.6e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
NHLFHNML_04385	7.11e-29	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
NHLFHNML_04386	1.32e-252	aprE	3.4.21.62	-	O	ko:K01342	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
NHLFHNML_04388	2.55e-285	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHLFHNML_04389	2.87e-216	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
NHLFHNML_04390	1.08e-177	-	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NHLFHNML_04392	2.83e-249	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
NHLFHNML_04407	1.47e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
NHLFHNML_04408	1.2e-132	-	-	-	L	-	-	-	Integrase core domain
NHLFHNML_04409	4.62e-103	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
NHLFHNML_04410	1.1e-73	-	-	-	L	-	-	-	IstB-like ATP binding protein
NHLFHNML_04411	9.72e-40	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives