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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MDLIIIGM_00001	2.16e-93	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_00003	3.9e-136	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MDLIIIGM_00007	7.68e-120	-	-	-	J	-	-	-	Aminoglycoside-2''-adenylyltransferase
MDLIIIGM_00008	4.77e-193	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDLIIIGM_00015	3.28e-114	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MDLIIIGM_00016	8.56e-39	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
MDLIIIGM_00017	1.89e-10	-	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MDLIIIGM_00018	1.02e-31	-	-	-	-	-	-	-	-
MDLIIIGM_00021	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDLIIIGM_00022	3.54e-100	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MDLIIIGM_00023	3.24e-118	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDLIIIGM_00024	1.23e-62	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
MDLIIIGM_00025	4.86e-27	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MDLIIIGM_00026	1.1e-42	yabO	-	-	J	-	-	-	S4 domain protein
MDLIIIGM_00027	2.32e-173	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MDLIIIGM_00028	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDLIIIGM_00029	1.45e-95	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDLIIIGM_00030	8.16e-202	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MDLIIIGM_00031	2.56e-109	-	-	-	S	-	-	-	(CBS) domain
MDLIIIGM_00032	3.13e-180	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDLIIIGM_00033	4.09e-261	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDLIIIGM_00034	1.43e-68	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MDLIIIGM_00035	1.65e-72	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MDLIIIGM_00036	5.31e-126	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
MDLIIIGM_00037	5.38e-145	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MDLIIIGM_00038	8.4e-66	-	-	-	M	-	-	-	LysM domain protein
MDLIIIGM_00039	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MDLIIIGM_00040	3.17e-111	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MDLIIIGM_00041	2.1e-41	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
MDLIIIGM_00042	1.62e-139	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MDLIIIGM_00043	1.81e-110	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_00044	1.79e-86	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MDLIIIGM_00045	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MDLIIIGM_00046	5.67e-307	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MDLIIIGM_00048	1.32e-78	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MDLIIIGM_00049	1.04e-99	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDLIIIGM_00050	1.08e-160	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDLIIIGM_00051	1.08e-138	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDLIIIGM_00052	2.51e-139	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDLIIIGM_00053	2.78e-128	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDLIIIGM_00054	4.47e-71	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MDLIIIGM_00055	1.93e-198	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDLIIIGM_00056	1.24e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDLIIIGM_00057	7.34e-74	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDLIIIGM_00058	1.72e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MDLIIIGM_00059	7.16e-47	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDLIIIGM_00060	3.12e-143	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDLIIIGM_00061	1.05e-266	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDLIIIGM_00062	1.13e-88	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MDLIIIGM_00063	1.65e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MDLIIIGM_00064	2.08e-106	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDLIIIGM_00065	2.4e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDLIIIGM_00066	4.99e-113	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDLIIIGM_00067	5.17e-86	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDLIIIGM_00068	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDLIIIGM_00069	1.61e-119	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDLIIIGM_00070	3.84e-62	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDLIIIGM_00071	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDLIIIGM_00072	5.05e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDLIIIGM_00073	2.63e-32	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MDLIIIGM_00074	8.95e-95	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDLIIIGM_00075	1.62e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDLIIIGM_00076	9.15e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDLIIIGM_00077	5.93e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDLIIIGM_00078	4.58e-183	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDLIIIGM_00079	1.34e-52	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDLIIIGM_00080	6.55e-130	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MDLIIIGM_00081	2.82e-140	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDLIIIGM_00082	7.65e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MDLIIIGM_00083	3.47e-217	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDLIIIGM_00084	1.44e-94	-	-	-	K	-	-	-	rpiR family
MDLIIIGM_00085	1.77e-38	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MDLIIIGM_00086	4.58e-185	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MDLIIIGM_00087	2.79e-14	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDLIIIGM_00088	8.22e-240	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MDLIIIGM_00089	5.35e-288	-	-	-	L	-	-	-	Probable transposase
MDLIIIGM_00092	2.71e-22	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
MDLIIIGM_00094	5.95e-238	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MDLIIIGM_00095	4.5e-20	-	3.1.11.5	-	L	ko:K01144,ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDLIIIGM_00096	1.55e-07	-	-	-	L	-	-	-	Participates in initiation and elongation during chromosome replication
MDLIIIGM_00097	1e-19	yvgN	-	-	C	-	-	-	Aldo keto reductase
MDLIIIGM_00098	3.84e-50	-	-	-	S	-	-	-	Haem-degrading
MDLIIIGM_00099	1.65e-210	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MDLIIIGM_00100	2.2e-204	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDLIIIGM_00101	3.53e-149	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MDLIIIGM_00102	1.51e-190	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MDLIIIGM_00103	1.54e-216	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MDLIIIGM_00104	2.84e-225	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDLIIIGM_00105	1.49e-18	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MDLIIIGM_00106	1.46e-110	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MDLIIIGM_00107	3.58e-236	-	-	-	E	-	-	-	SAF
MDLIIIGM_00108	2.69e-24	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MDLIIIGM_00109	2.31e-94	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
MDLIIIGM_00110	5.7e-138	pts38BC	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
MDLIIIGM_00111	4.32e-11	-	-	-	K	ko:K02466	-	ko00000	Glucitol operon activator protein (GutM)
MDLIIIGM_00112	1.27e-59	deoR_2	-	-	K	-	-	-	Putative sugar-binding domain
MDLIIIGM_00113	2.92e-115	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MDLIIIGM_00114	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MDLIIIGM_00115	7.03e-72	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
MDLIIIGM_00116	9.79e-142	garR	1.1.1.60	-	I	ko:K00042	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MDLIIIGM_00117	1.28e-189	-	-	-	S	-	-	-	Protein conserved in bacteria
MDLIIIGM_00118	1.66e-174	-	-	-	EG	ko:K06155	-	ko00000,ko02000	Gluconate
MDLIIIGM_00120	2.03e-75	-	-	-	S	-	-	-	COG NOG19168 non supervised orthologous group
MDLIIIGM_00121	4.97e-15	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
MDLIIIGM_00122	1.44e-38	-	-	-	S	ko:K07334	-	ko00000,ko02048	RelE-like toxin of type II toxin-antitoxin system HigB
MDLIIIGM_00123	1.11e-37	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDLIIIGM_00124	7.41e-07	-	-	-	-	-	-	-	-
MDLIIIGM_00125	1.43e-240	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MDLIIIGM_00127	2.42e-113	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_00128	2.51e-67	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MDLIIIGM_00129	3e-108	-	-	-	L	ko:K07496	-	ko00000	Transposase, IS605 OrfB family
MDLIIIGM_00130	2.29e-09	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_00132	3.2e-62	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MDLIIIGM_00134	1.02e-205	-	-	-	L	-	-	-	T/G mismatch-specific endonuclease activity
MDLIIIGM_00135	2.85e-76	-	-	-	-	-	-	-	-
MDLIIIGM_00136	7.22e-85	-	-	-	-	-	-	-	-
MDLIIIGM_00137	0.000777	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
MDLIIIGM_00138	2.22e-117	-	-	-	S	-	-	-	SIR2-like domain
MDLIIIGM_00139	3.38e-296	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
MDLIIIGM_00141	6.1e-122	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
MDLIIIGM_00142	6.24e-26	-	-	-	K	-	-	-	Transcriptional
MDLIIIGM_00143	1.95e-122	-	-	-	L	-	-	-	Type II restriction endonuclease, TdeIII
MDLIIIGM_00144	4.99e-114	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MDLIIIGM_00147	3.35e-216	potE2	-	-	E	ko:K03294	-	ko00000	amino acid
MDLIIIGM_00148	4.92e-20	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MDLIIIGM_00149	7.79e-148	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MDLIIIGM_00150	3.77e-74	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MDLIIIGM_00151	8.37e-103	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MDLIIIGM_00152	1.24e-47	-	-	-	S	-	-	-	Enterocin A Immunity
MDLIIIGM_00153	1.73e-49	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDLIIIGM_00154	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MDLIIIGM_00155	1.08e-104	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
MDLIIIGM_00156	4.57e-32	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MDLIIIGM_00158	3.89e-130	yvgN	-	-	C	-	-	-	Aldo keto reductase
MDLIIIGM_00163	5.61e-102	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
MDLIIIGM_00164	1.23e-107	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDLIIIGM_00165	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDLIIIGM_00166	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDLIIIGM_00167	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDLIIIGM_00168	4.11e-143	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDLIIIGM_00169	4.12e-168	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDLIIIGM_00170	2.17e-35	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MDLIIIGM_00171	1.02e-10	-	-	-	K	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MDLIIIGM_00172	1.18e-102	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDLIIIGM_00173	7.27e-111	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MDLIIIGM_00174	3.12e-79	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
MDLIIIGM_00175	7.54e-206	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDLIIIGM_00176	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDLIIIGM_00177	5.54e-119	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Major Facilitator Superfamily
MDLIIIGM_00178	7.08e-105	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDLIIIGM_00179	1.13e-146	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_00181	9.14e-46	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDLIIIGM_00183	2.23e-57	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
MDLIIIGM_00190	1.06e-23	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
MDLIIIGM_00191	6.03e-165	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
MDLIIIGM_00193	1.02e-08	-	-	-	-	-	-	-	-
MDLIIIGM_00194	3.7e-67	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MDLIIIGM_00195	3.04e-159	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MDLIIIGM_00196	3.75e-200	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
MDLIIIGM_00197	0.0	ydaO	-	-	E	-	-	-	amino acid
MDLIIIGM_00198	0.0	-	-	-	P	ko:K12952	-	ko00000,ko01000	COG COG0474 Cation transport ATPase
MDLIIIGM_00199	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDLIIIGM_00200	1.7e-46	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDLIIIGM_00201	2.85e-41	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDLIIIGM_00202	1.52e-126	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDLIIIGM_00203	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MDLIIIGM_00204	2.92e-205	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDLIIIGM_00205	1.9e-19	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MDLIIIGM_00206	8.6e-87	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MDLIIIGM_00207	2.69e-176	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
MDLIIIGM_00208	6.03e-105	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MDLIIIGM_00209	9.92e-121	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDLIIIGM_00210	3.85e-52	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MDLIIIGM_00211	4.64e-105	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDLIIIGM_00212	5.37e-84	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDLIIIGM_00213	1.7e-164	-	-	-	L	ko:K07498	-	ko00000	DDE domain
MDLIIIGM_00214	4.79e-44	-	-	-	-	-	-	-	-
MDLIIIGM_00230	4.25e-121	-	-	-	-	-	-	-	-
MDLIIIGM_00231	6.71e-14	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
MDLIIIGM_00232	1e-68	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MDLIIIGM_00233	3.05e-269	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MDLIIIGM_00234	4.88e-315	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDLIIIGM_00235	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDLIIIGM_00236	8.78e-102	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDLIIIGM_00237	6.84e-232	yhdP	-	-	S	-	-	-	Transporter associated domain
MDLIIIGM_00238	1.95e-33	-	-	-	-	-	-	-	-
MDLIIIGM_00239	3.41e-94	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MDLIIIGM_00240	4.55e-162	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
MDLIIIGM_00241	3.23e-125	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MDLIIIGM_00242	5.65e-92	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDLIIIGM_00243	8.03e-199	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MDLIIIGM_00244	1.97e-174	-	-	-	V	-	-	-	MatE
MDLIIIGM_00245	2.95e-58	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDLIIIGM_00246	7.83e-111	-	-	-	S	-	-	-	Alpha beta hydrolase
MDLIIIGM_00247	7.48e-122	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDLIIIGM_00248	7.42e-219	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDLIIIGM_00249	4.34e-138	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
MDLIIIGM_00250	1.49e-129	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MDLIIIGM_00251	8.54e-45	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
MDLIIIGM_00252	3.29e-70	ccl	-	-	S	-	-	-	QueT transporter
MDLIIIGM_00254	3.29e-84	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
MDLIIIGM_00255	8.32e-29	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDLIIIGM_00256	2.19e-28	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDLIIIGM_00257	1.12e-45	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MDLIIIGM_00258	6.91e-109	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDLIIIGM_00259	1.6e-154	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDLIIIGM_00260	1.97e-64	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MDLIIIGM_00261	9.59e-104	-	-	-	S	-	-	-	Putative threonine/serine exporter
MDLIIIGM_00262	1.37e-37	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MDLIIIGM_00263	1.77e-115	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
MDLIIIGM_00264	1.01e-117	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDLIIIGM_00265	1.23e-27	-	-	-	-	-	-	-	-
MDLIIIGM_00266	6.46e-75	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
MDLIIIGM_00267	1.65e-24	-	-	-	-	-	-	-	-
MDLIIIGM_00268	3.45e-81	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MDLIIIGM_00269	2.61e-52	-	-	-	S	-	-	-	branched-chain amino acid
MDLIIIGM_00270	3.58e-132	-	-	-	E	-	-	-	AzlC protein
MDLIIIGM_00271	1.81e-24	-	-	-	-	-	-	-	-
MDLIIIGM_00272	7.25e-163	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MDLIIIGM_00273	1.2e-155	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
MDLIIIGM_00274	0.000904	-	-	-	S	-	-	-	zinc-ribbon domain
MDLIIIGM_00276	8.68e-159	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDLIIIGM_00277	3.66e-216	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MDLIIIGM_00278	1.48e-148	ydbI	-	-	K	-	-	-	AI-2E family transporter
MDLIIIGM_00279	2.09e-76	-	-	-	EG	-	-	-	EamA-like transporter family
MDLIIIGM_00280	1.3e-97	nt5e	3.1.3.18	-	L	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
MDLIIIGM_00281	4.86e-148	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MDLIIIGM_00282	6.44e-34	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDLIIIGM_00283	5.56e-32	-	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
MDLIIIGM_00284	4.16e-118	-	-	-	C	-	-	-	Luciferase-like monooxygenase
MDLIIIGM_00285	3.18e-27	-	-	-	C	-	-	-	Luciferase-like monooxygenase
MDLIIIGM_00286	1.98e-10	-	-	-	M	-	-	-	Rib/alpha-like repeat
MDLIIIGM_00288	0.0	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
MDLIIIGM_00289	5.83e-113	-	-	-	S	-	-	-	Phage tail protein
MDLIIIGM_00290	8.11e-115	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MDLIIIGM_00297	2.35e-116	-	-	-	S	-	-	-	Phage capsid family
MDLIIIGM_00298	1.72e-91	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MDLIIIGM_00299	2.41e-125	-	-	-	S	-	-	-	Phage portal protein, HK97 family
MDLIIIGM_00300	3.51e-269	-	-	-	S	-	-	-	Terminase
MDLIIIGM_00301	3.33e-43	-	-	-	L	-	-	-	Phage terminase, small subunit
MDLIIIGM_00302	2.29e-24	-	-	-	L	-	-	-	HNH endonuclease
MDLIIIGM_00307	8.63e-72	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MDLIIIGM_00314	2.74e-81	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
MDLIIIGM_00318	1.85e-86	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MDLIIIGM_00320	1.18e-72	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_00321	1.07e-28	-	-	-	S	-	-	-	HNH endonuclease
MDLIIIGM_00322	3.1e-11	-	-	-	-	-	-	-	-
MDLIIIGM_00326	7.84e-46	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
MDLIIIGM_00329	9.82e-190	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family
MDLIIIGM_00330	1.85e-220	-	-	-	L	-	-	-	DNA polymerase elongation subunit (Family B)
MDLIIIGM_00331	1.76e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
MDLIIIGM_00332	3.13e-157	-	-	-	L	-	-	-	AAA domain
MDLIIIGM_00336	4.33e-140	-	-	-	L	-	-	-	snf2 family
MDLIIIGM_00341	1.82e-25	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
MDLIIIGM_00344	7.74e-44	-	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_00345	1.58e-19	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDLIIIGM_00346	3.85e-38	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDLIIIGM_00348	1.63e-18	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
MDLIIIGM_00349	0.000447	-	-	-	-	-	-	-	-
MDLIIIGM_00352	1.22e-20	-	-	-	-	-	-	-	-
MDLIIIGM_00353	1.56e-142	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_00354	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDLIIIGM_00355	5.21e-55	-	-	-	S	-	-	-	repeat protein
MDLIIIGM_00356	4.85e-128	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
MDLIIIGM_00357	3.01e-57	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
MDLIIIGM_00358	1.18e-116	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
MDLIIIGM_00359	7.75e-256	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MDLIIIGM_00361	2.4e-146	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDLIIIGM_00362	1.49e-193	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MDLIIIGM_00363	1.93e-253	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MDLIIIGM_00364	3.94e-249	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDLIIIGM_00365	1.91e-187	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDLIIIGM_00366	4.48e-158	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDLIIIGM_00367	1.54e-140	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MDLIIIGM_00369	6.82e-235	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDLIIIGM_00370	3.44e-66	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MDLIIIGM_00371	7.37e-175	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MDLIIIGM_00372	1.36e-71	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MDLIIIGM_00373	5.57e-257	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDLIIIGM_00374	2.25e-216	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDLIIIGM_00375	4.52e-27	rimL	1.1.1.25	-	J	ko:K00014,ko:K03817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MDLIIIGM_00377	5.54e-139	dkgB	-	-	S	-	-	-	reductase
MDLIIIGM_00378	1.82e-33	-	-	-	-	-	-	-	-
MDLIIIGM_00379	1.6e-78	-	-	-	L	-	-	-	Resolvase, N-terminal domain
MDLIIIGM_00380	1.45e-120	-	-	-	L	-	-	-	Probable transposase
MDLIIIGM_00381	6.86e-100	-	-	-	F	-	-	-	Phosphorylase superfamily
MDLIIIGM_00382	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MDLIIIGM_00383	3.47e-79	ytkL	-	-	S	-	-	-	Beta-lactamase superfamily domain
MDLIIIGM_00384	2.86e-123	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDLIIIGM_00385	4.53e-156	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MDLIIIGM_00386	3.33e-110	-	-	-	S	-	-	-	overlaps another CDS with the same product name
MDLIIIGM_00388	6.78e-63	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
MDLIIIGM_00390	4.5e-89	-	-	-	L	-	-	-	recombinase activity
MDLIIIGM_00391	9.07e-91	-	-	-	-	-	-	-	-
MDLIIIGM_00392	8.64e-24	-	-	-	-	-	-	-	-
MDLIIIGM_00393	1.28e-88	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
MDLIIIGM_00394	1.01e-110	-	-	-	S	-	-	-	hydrolase
MDLIIIGM_00395	2.43e-261	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
MDLIIIGM_00396	1e-109	-	-	-	F	-	-	-	glutamine amidotransferase
MDLIIIGM_00397	1.8e-32	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MDLIIIGM_00398	8.08e-58	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDLIIIGM_00399	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDLIIIGM_00402	3.79e-254	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDLIIIGM_00403	9.6e-241	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MDLIIIGM_00404	2.05e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MDLIIIGM_00405	7.83e-79	-	-	-	-	-	-	-	-
MDLIIIGM_00406	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MDLIIIGM_00407	2.48e-125	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MDLIIIGM_00408	2.92e-189	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MDLIIIGM_00409	7.81e-147	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MDLIIIGM_00410	3.12e-187	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDLIIIGM_00411	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MDLIIIGM_00412	1.22e-95	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
MDLIIIGM_00413	3.57e-33	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MDLIIIGM_00414	1.86e-22	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily
MDLIIIGM_00415	1.36e-111	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDLIIIGM_00416	4.97e-33	-	-	-	-	-	-	-	-
MDLIIIGM_00417	1.47e-30	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MDLIIIGM_00418	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDLIIIGM_00419	3.87e-315	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDLIIIGM_00420	2.59e-251	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDLIIIGM_00421	4.78e-246	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDLIIIGM_00422	1.38e-273	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDLIIIGM_00423	0.000113	-	-	-	S	-	-	-	Tetratricopeptide repeat
MDLIIIGM_00424	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDLIIIGM_00425	7.62e-147	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDLIIIGM_00426	2.6e-53	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDLIIIGM_00427	1.33e-43	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MDLIIIGM_00428	2.49e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDLIIIGM_00429	3.56e-250	-	-	-	E	ko:K03294	-	ko00000	amino acid
MDLIIIGM_00430	2.19e-78	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MDLIIIGM_00431	2.74e-145	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MDLIIIGM_00432	2.27e-74	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDLIIIGM_00433	4.89e-38	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MDLIIIGM_00434	1.32e-55	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MDLIIIGM_00435	9.04e-263	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDLIIIGM_00436	6.15e-53	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDLIIIGM_00437	1.84e-186	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDLIIIGM_00438	6.58e-289	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MDLIIIGM_00439	4.17e-129	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDLIIIGM_00440	9.72e-35	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDLIIIGM_00441	1.08e-180	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDLIIIGM_00442	1.1e-305	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDLIIIGM_00443	1.21e-302	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MDLIIIGM_00444	7.35e-69	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MDLIIIGM_00445	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MDLIIIGM_00446	4.29e-260	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MDLIIIGM_00449	1.5e-115	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDLIIIGM_00450	9.25e-124	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
MDLIIIGM_00451	3.32e-113	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDLIIIGM_00452	3.1e-307	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDLIIIGM_00453	2.65e-165	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDLIIIGM_00454	5.71e-317	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
MDLIIIGM_00455	9.77e-56	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MDLIIIGM_00457	2.66e-148	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDLIIIGM_00458	2.13e-163	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
MDLIIIGM_00459	4.1e-109	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDLIIIGM_00460	3.93e-45	-	-	-	S	-	-	-	Enterocin A Immunity
MDLIIIGM_00461	5.18e-281	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MDLIIIGM_00462	1.17e-25	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MDLIIIGM_00463	3.38e-95	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MDLIIIGM_00464	2.79e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDLIIIGM_00465	1.38e-195	yacL	-	-	S	-	-	-	domain protein
MDLIIIGM_00466	1.05e-312	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDLIIIGM_00467	2.26e-263	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDLIIIGM_00468	3.45e-73	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDLIIIGM_00469	1.88e-138	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDLIIIGM_00470	1.93e-92	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
MDLIIIGM_00471	3.3e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDLIIIGM_00472	3.08e-16	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDLIIIGM_00473	3.13e-109	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MDLIIIGM_00474	2.58e-88	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDLIIIGM_00475	9.98e-150	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDLIIIGM_00476	2.21e-97	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDLIIIGM_00477	2.18e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDLIIIGM_00478	7.33e-71	-	-	-	-	-	-	-	-
MDLIIIGM_00479	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDLIIIGM_00480	1.1e-203	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDLIIIGM_00481	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDLIIIGM_00482	1.81e-58	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MDLIIIGM_00483	3.91e-37	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MDLIIIGM_00484	1.11e-96	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MDLIIIGM_00485	2.23e-80	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDLIIIGM_00486	5.45e-268	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDLIIIGM_00487	3.8e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDLIIIGM_00488	6.62e-126	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDLIIIGM_00489	4.16e-39	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MDLIIIGM_00490	4.04e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MDLIIIGM_00491	1.19e-145	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDLIIIGM_00492	4.29e-77	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MDLIIIGM_00493	4.57e-73	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDLIIIGM_00494	2.02e-237	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MDLIIIGM_00495	4.62e-122	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MDLIIIGM_00499	7.13e-18	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
MDLIIIGM_00500	8.75e-36	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MDLIIIGM_00501	1.19e-71	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MDLIIIGM_00502	1.58e-153	-	-	-	L	-	-	-	ISXO2-like transposase domain
MDLIIIGM_00504	3.88e-06	-	-	-	L	-	-	-	DNA restriction-modification system
MDLIIIGM_00505	1.4e-97	-	-	-	V	-	-	-	N-6 DNA Methylase
MDLIIIGM_00506	4.28e-25	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MDLIIIGM_00507	1.29e-151	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MDLIIIGM_00508	4.7e-129	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDLIIIGM_00509	1.98e-153	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MDLIIIGM_00510	4.81e-54	-	-	-	S	-	-	-	VanZ like family
MDLIIIGM_00511	1.26e-202	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MDLIIIGM_00512	9.17e-219	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MDLIIIGM_00514	2.23e-10	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDLIIIGM_00516	3.43e-96	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDLIIIGM_00517	3.39e-47	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MDLIIIGM_00518	5.92e-83	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MDLIIIGM_00519	1.13e-52	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MDLIIIGM_00520	2.71e-107	-	-	-	S	-	-	-	membrane
MDLIIIGM_00521	5.64e-100	-	-	-	S	-	-	-	VIT family
MDLIIIGM_00522	1.21e-188	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
MDLIIIGM_00523	2.26e-73	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MDLIIIGM_00524	6.43e-149	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDLIIIGM_00525	7.48e-147	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDLIIIGM_00526	1.35e-154	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MDLIIIGM_00527	5.19e-150	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MDLIIIGM_00528	4.34e-125	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MDLIIIGM_00529	1.3e-53	yjbH	-	-	Q	-	-	-	Thioredoxin
MDLIIIGM_00530	2.89e-287	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MDLIIIGM_00531	1.21e-83	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MDLIIIGM_00532	1.08e-61	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDLIIIGM_00533	1.78e-273	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
MDLIIIGM_00546	1.63e-113	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDLIIIGM_00547	7.25e-214	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MDLIIIGM_00548	2.44e-160	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDLIIIGM_00549	1.47e-223	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MDLIIIGM_00550	4.49e-94	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDLIIIGM_00551	2.02e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MDLIIIGM_00552	9.64e-109	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
MDLIIIGM_00553	4.77e-72	-	-	-	-	-	-	-	-
MDLIIIGM_00554	7.59e-88	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MDLIIIGM_00555	4.36e-193	XK27_08315	-	-	M	-	-	-	Sulfatase
MDLIIIGM_00556	4.5e-149	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
MDLIIIGM_00557	4.55e-20	-	-	-	-	-	-	-	-
MDLIIIGM_00558	5.46e-58	cps3I	-	-	G	-	-	-	Acyltransferase family
MDLIIIGM_00559	5.48e-188	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MDLIIIGM_00560	6.39e-69	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
MDLIIIGM_00561	3.92e-194	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MDLIIIGM_00562	1.23e-85	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MDLIIIGM_00563	2.13e-118	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDLIIIGM_00564	7.97e-206	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDLIIIGM_00565	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDLIIIGM_00566	9.94e-58	-	-	-	S	-	-	-	zinc-ribbon domain
MDLIIIGM_00567	1.56e-161	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MDLIIIGM_00569	5.17e-104	-	-	-	G	-	-	-	Peptidase_C39 like family
MDLIIIGM_00570	3.23e-262	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDLIIIGM_00571	7.55e-308	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MDLIIIGM_00572	7.88e-87	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
MDLIIIGM_00573	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MDLIIIGM_00574	4.07e-14	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MDLIIIGM_00575	5.31e-72	lssY	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
MDLIIIGM_00576	2.71e-106	lysR5	-	-	K	-	-	-	LysR substrate binding domain
MDLIIIGM_00577	3.86e-154	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MDLIIIGM_00578	1.39e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1634)
MDLIIIGM_00579	6.86e-159	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDLIIIGM_00580	7.34e-285	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDLIIIGM_00581	8.89e-21	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDLIIIGM_00582	4.13e-208	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
MDLIIIGM_00583	6.81e-103	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
MDLIIIGM_00584	3.67e-172	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MDLIIIGM_00585	2.47e-185	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDLIIIGM_00586	1.86e-35	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
MDLIIIGM_00587	1.68e-69	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
MDLIIIGM_00588	2.05e-189	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MDLIIIGM_00589	2.47e-146	degV	-	-	S	-	-	-	EDD domain protein, DegV family
MDLIIIGM_00590	3.6e-293	cadA	-	-	P	-	-	-	P-type ATPase
MDLIIIGM_00591	0.0	-	-	-	E	-	-	-	Amino acid permease
MDLIIIGM_00592	2.22e-108	-	-	-	S	-	-	-	Membrane
MDLIIIGM_00593	3.27e-57	cps3F	-	-	-	-	-	-	-
MDLIIIGM_00594	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
MDLIIIGM_00595	4.7e-192	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDLIIIGM_00596	1.2e-112	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
MDLIIIGM_00597	7.63e-279	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MDLIIIGM_00598	3.81e-37	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MDLIIIGM_00599	2.52e-17	-	-	-	-	-	-	-	-
MDLIIIGM_00600	1.57e-77	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MDLIIIGM_00601	2.36e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
MDLIIIGM_00602	9.52e-187	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MDLIIIGM_00603	4.36e-291	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
MDLIIIGM_00604	6.36e-229	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDLIIIGM_00605	6.13e-212	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
MDLIIIGM_00606	2.47e-222	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MDLIIIGM_00609	9.21e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF4256)
MDLIIIGM_00610	3.63e-163	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MDLIIIGM_00611	1.02e-73	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDLIIIGM_00612	1.53e-192	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDLIIIGM_00614	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
MDLIIIGM_00615	1.29e-215	npr	1.11.1.1	-	S	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MDLIIIGM_00616	2.34e-136	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MDLIIIGM_00617	4.37e-106	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
MDLIIIGM_00618	2.84e-107	-	-	-	C	-	-	-	nitroreductase
MDLIIIGM_00619	3.22e-168	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MDLIIIGM_00620	7.43e-119	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDLIIIGM_00621	5.34e-188	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDLIIIGM_00622	4.23e-135	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MDLIIIGM_00623	1.03e-176	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MDLIIIGM_00624	5.1e-60	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MDLIIIGM_00625	6.56e-73	yphH	-	-	S	-	-	-	Cupin domain
MDLIIIGM_00626	6.01e-60	-	-	-	C	-	-	-	Flavodoxin
MDLIIIGM_00627	4.1e-70	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDLIIIGM_00628	2.22e-131	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MDLIIIGM_00629	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDLIIIGM_00630	6.13e-286	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDLIIIGM_00631	6.58e-70	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDLIIIGM_00632	8.27e-86	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MDLIIIGM_00633	2.85e-138	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_00634	9.74e-147	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MDLIIIGM_00635	3.21e-168	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MDLIIIGM_00636	1.38e-200	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDLIIIGM_00637	1.26e-132	potC	-	-	U	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MDLIIIGM_00638	3.16e-152	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDLIIIGM_00639	8.99e-212	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDLIIIGM_00640	3.27e-130	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDLIIIGM_00641	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
MDLIIIGM_00642	1.18e-295	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDLIIIGM_00644	8.46e-23	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
MDLIIIGM_00645	3.71e-09	-	-	-	S	-	-	-	Putative adhesin
MDLIIIGM_00646	2.01e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
MDLIIIGM_00647	1.03e-50	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
MDLIIIGM_00648	3.61e-43	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
MDLIIIGM_00649	1.36e-96	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
MDLIIIGM_00650	5.63e-207	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDLIIIGM_00651	4.1e-164	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MDLIIIGM_00652	4.25e-92	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
MDLIIIGM_00653	7.96e-68	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
MDLIIIGM_00654	1.4e-188	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MDLIIIGM_00655	1.69e-153	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
MDLIIIGM_00656	3.19e-192	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MDLIIIGM_00657	3.08e-101	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	sugar-binding domain protein
MDLIIIGM_00658	2.16e-120	baeS	-	-	T	-	-	-	Histidine kinase
MDLIIIGM_00659	1.51e-101	yfiK	-	-	K	ko:K02479	-	ko00000,ko02022	Bacterial regulatory proteins, luxR family
MDLIIIGM_00660	5.94e-148	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MDLIIIGM_00661	1.22e-89	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MDLIIIGM_00662	9.06e-52	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDLIIIGM_00663	1.24e-43	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MDLIIIGM_00664	1.41e-246	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MDLIIIGM_00665	2.82e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MDLIIIGM_00666	2.88e-50	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDLIIIGM_00667	5.58e-63	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MDLIIIGM_00668	5.62e-92	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MDLIIIGM_00669	2.69e-116	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MDLIIIGM_00670	2.6e-230	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
MDLIIIGM_00671	7.69e-71	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MDLIIIGM_00672	3.21e-112	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
MDLIIIGM_00673	4.02e-28	-	-	-	-	-	-	-	-
MDLIIIGM_00674	3.37e-16	epsJ2	-	-	S	-	-	-	Glycosyltransferase like family 2
MDLIIIGM_00675	7.12e-68	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MDLIIIGM_00676	1.53e-74	-	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
MDLIIIGM_00677	1.2e-144	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MDLIIIGM_00678	1.37e-229	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MDLIIIGM_00679	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDLIIIGM_00680	5.21e-269	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MDLIIIGM_00681	9.33e-186	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MDLIIIGM_00682	2.1e-305	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MDLIIIGM_00683	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDLIIIGM_00684	2.12e-152	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
MDLIIIGM_00685	3.09e-59	ykuL	-	-	S	-	-	-	CBS domain
MDLIIIGM_00686	2.43e-92	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDLIIIGM_00687	4.06e-224	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDLIIIGM_00688	2.28e-115	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MDLIIIGM_00691	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MDLIIIGM_00692	2.92e-28	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MDLIIIGM_00693	1.32e-162	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDLIIIGM_00694	1.35e-96	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
MDLIIIGM_00695	1.22e-144	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDLIIIGM_00697	3.15e-69	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
MDLIIIGM_00698	8.15e-122	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_00699	8.93e-87	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MDLIIIGM_00700	3.39e-125	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
MDLIIIGM_00701	8.2e-131	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDLIIIGM_00702	5.96e-59	ytpP	-	-	CO	-	-	-	Thioredoxin
MDLIIIGM_00703	2.58e-97	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDLIIIGM_00704	1.07e-10	-	-	-	-	-	-	-	-
MDLIIIGM_00707	5.63e-20	-	-	-	L	-	-	-	DnaD domain protein
MDLIIIGM_00714	1.46e-59	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
MDLIIIGM_00716	2.52e-20	ansR	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_00717	3.08e-152	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_00718	6e-299	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDLIIIGM_00719	7.15e-282	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MDLIIIGM_00720	6.4e-80	phaJ	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
MDLIIIGM_00721	1.2e-87	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MDLIIIGM_00727	1.05e-82	-	-	-	H	-	-	-	Methyltransferase domain
MDLIIIGM_00728	3.26e-93	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MDLIIIGM_00729	3.92e-52	-	-	-	M	-	-	-	Acetyltransferase (GNAT) family
MDLIIIGM_00731	4.47e-29	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
MDLIIIGM_00732	2.29e-51	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MDLIIIGM_00734	0.0	-	-	-	L	-	-	-	helicase
MDLIIIGM_00735	1.99e-80	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
MDLIIIGM_00736	4.83e-41	-	-	-	S	-	-	-	CHY zinc finger
MDLIIIGM_00737	2.54e-53	ywnA	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_00738	4.86e-106	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
MDLIIIGM_00740	6.74e-52	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDLIIIGM_00741	4.57e-223	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MDLIIIGM_00742	4.68e-81	-	-	-	-	-	-	-	-
MDLIIIGM_00743	7.47e-104	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MDLIIIGM_00744	5.02e-144	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MDLIIIGM_00745	1.12e-77	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDLIIIGM_00746	8.93e-237	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDLIIIGM_00747	5.92e-33	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MDLIIIGM_00748	7.9e-267	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MDLIIIGM_00750	2.95e-80	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MDLIIIGM_00751	7.03e-57	-	-	-	S	-	-	-	Membrane
MDLIIIGM_00752	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MDLIIIGM_00753	1.99e-107	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDLIIIGM_00754	6.53e-49	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDLIIIGM_00756	2.37e-181	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
MDLIIIGM_00757	8.2e-235	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MDLIIIGM_00758	7.01e-248	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MDLIIIGM_00759	5.49e-150	-	-	-	M	-	-	-	Core-2/I-Branching enzyme
MDLIIIGM_00760	2.93e-116	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
MDLIIIGM_00761	1.29e-161	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MDLIIIGM_00762	5.99e-142	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MDLIIIGM_00763	1.14e-117	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MDLIIIGM_00764	5.82e-93	epsB	-	-	M	-	-	-	biosynthesis protein
MDLIIIGM_00766	7.76e-140	cps2J	-	-	S	-	-	-	Polysaccharide biosynthesis protein
MDLIIIGM_00767	1.61e-82	-	-	-	S	ko:K16710	-	ko00000	Polysaccharide pyruvyl transferase
MDLIIIGM_00769	3.61e-30	-	-	-	M	-	-	-	family 8
MDLIIIGM_00770	1.53e-113	-	-	-	-	-	-	-	-
MDLIIIGM_00771	2.23e-49	-	-	-	M	-	-	-	group 2 family protein
MDLIIIGM_00772	1.35e-121	-	-	-	M	-	-	-	Glycosyl transferase family 8
MDLIIIGM_00773	3.67e-110	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MDLIIIGM_00775	2.88e-146	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
MDLIIIGM_00776	1.2e-165	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDLIIIGM_00777	7.18e-236	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDLIIIGM_00778	2.26e-130	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MDLIIIGM_00779	2.69e-179	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDLIIIGM_00780	1.03e-75	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MDLIIIGM_00781	1.41e-148	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MDLIIIGM_00782	4.74e-45	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MDLIIIGM_00783	2.62e-114	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MDLIIIGM_00784	2.95e-81	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
MDLIIIGM_00785	7.52e-193	-	-	-	EGP	-	-	-	Major Facilitator
MDLIIIGM_00787	1.09e-87	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDLIIIGM_00788	9.23e-36	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
MDLIIIGM_00789	5.11e-112	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MDLIIIGM_00791	4.13e-185	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MDLIIIGM_00792	6.85e-98	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MDLIIIGM_00793	5.44e-130	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDLIIIGM_00794	1.76e-232	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MDLIIIGM_00795	1.13e-82	-	-	-	L	-	-	-	DNA alkylation repair enzyme
MDLIIIGM_00796	1.72e-174	-	-	-	EG	-	-	-	EamA-like transporter family
MDLIIIGM_00797	2.75e-190	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MDLIIIGM_00798	3.65e-255	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MDLIIIGM_00799	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDLIIIGM_00800	1.24e-173	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MDLIIIGM_00802	1.34e-220	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MDLIIIGM_00803	4.92e-165	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDLIIIGM_00804	1.21e-104	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MDLIIIGM_00806	1.26e-119	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDLIIIGM_00807	1.65e-201	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MDLIIIGM_00808	5.49e-54	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MDLIIIGM_00809	5.64e-256	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDLIIIGM_00810	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDLIIIGM_00811	6.47e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
MDLIIIGM_00812	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MDLIIIGM_00813	1.7e-211	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDLIIIGM_00814	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MDLIIIGM_00815	9.85e-161	-	-	-	Q	-	-	-	Thiopurine S-methyltransferase (TPMT)
MDLIIIGM_00816	1.96e-29	-	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
MDLIIIGM_00817	3.89e-206	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MDLIIIGM_00818	1.64e-121	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MDLIIIGM_00819	3.99e-72	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
MDLIIIGM_00820	4.14e-97	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MDLIIIGM_00821	7.95e-163	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MDLIIIGM_00822	1.67e-119	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MDLIIIGM_00823	9.96e-116	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_00824	1.31e-137	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MDLIIIGM_00825	6.26e-123	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MDLIIIGM_00826	1.55e-195	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
MDLIIIGM_00828	2.65e-82	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MDLIIIGM_00829	6.07e-179	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDLIIIGM_00830	1.05e-13	ftsL	-	-	D	-	-	-	Essential cell division protein
MDLIIIGM_00831	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDLIIIGM_00832	3.64e-172	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDLIIIGM_00833	2.56e-234	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDLIIIGM_00834	1.05e-195	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDLIIIGM_00835	6.44e-76	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDLIIIGM_00836	6.07e-240	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDLIIIGM_00837	4.52e-229	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDLIIIGM_00838	8.14e-43	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDLIIIGM_00839	8.19e-27	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MDLIIIGM_00840	1.4e-104	ylmH	-	-	S	-	-	-	S4 domain protein
MDLIIIGM_00841	1.61e-91	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MDLIIIGM_00842	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDLIIIGM_00843	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDLIIIGM_00844	1.85e-161	-	-	-	-	-	-	-	-
MDLIIIGM_00845	7.19e-189	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MDLIIIGM_00846	5.94e-54	-	-	-	ET	-	-	-	Bacterial extracellular solute-binding proteins, family 3
MDLIIIGM_00847	5.39e-40	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDLIIIGM_00848	3.03e-86	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MDLIIIGM_00849	1.19e-105	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MDLIIIGM_00850	1.6e-128	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MDLIIIGM_00851	2.31e-216	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MDLIIIGM_00852	2.75e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDLIIIGM_00853	0.0	-	-	-	L	-	-	-	DNA helicase
MDLIIIGM_00855	1.77e-155	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MDLIIIGM_00856	2.31e-94	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MDLIIIGM_00857	1.2e-67	ymdB	-	-	L	-	-	-	phosphatase homologous to the C-terminal domain of histone macroH2A1
MDLIIIGM_00858	5.29e-59	yyaT	-	-	K	ko:K02348	-	ko00000	protein acetylation
MDLIIIGM_00859	1.29e-11	-	-	-	-	-	-	-	-
MDLIIIGM_00860	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MDLIIIGM_00861	7.59e-279	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_00862	6.28e-44	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDLIIIGM_00863	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_00864	1.1e-277	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDLIIIGM_00865	2.38e-189	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MDLIIIGM_00866	4.13e-48	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MDLIIIGM_00867	1.19e-151	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDLIIIGM_00868	1.6e-24	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MDLIIIGM_00869	1.01e-171	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MDLIIIGM_00870	4.27e-143	-	-	-	-	-	-	-	-
MDLIIIGM_00871	3.98e-148	-	-	-	-	-	-	-	-
MDLIIIGM_00872	1.45e-48	-	-	-	S	-	-	-	Protein conserved in bacteria
MDLIIIGM_00873	3.77e-123	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDLIIIGM_00874	1.4e-60	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MDLIIIGM_00875	7.18e-47	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDLIIIGM_00876	3.32e-133	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDLIIIGM_00877	2.46e-183	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDLIIIGM_00878	1.44e-23	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDLIIIGM_00879	2.17e-103	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDLIIIGM_00880	6.31e-154	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MDLIIIGM_00881	5.91e-65	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MDLIIIGM_00882	1.49e-235	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MDLIIIGM_00883	1.29e-106	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDLIIIGM_00884	7.41e-41	ynzC	-	-	S	-	-	-	UPF0291 protein
MDLIIIGM_00885	6.62e-35	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MDLIIIGM_00886	1.38e-119	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MDLIIIGM_00887	2.16e-58	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
MDLIIIGM_00888	8.17e-88	yciQ	-	-	P	-	-	-	membrane protein (DUF2207)
MDLIIIGM_00890	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MDLIIIGM_00891	2.55e-49	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDLIIIGM_00892	9.08e-90	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
MDLIIIGM_00893	1.74e-34	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MDLIIIGM_00894	8.22e-203	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MDLIIIGM_00895	1.69e-59	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MDLIIIGM_00896	3.58e-23	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MDLIIIGM_00897	4.97e-140	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDLIIIGM_00898	1.56e-257	ynbB	-	-	P	-	-	-	aluminum resistance
MDLIIIGM_00899	1.3e-59	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
MDLIIIGM_00900	3.28e-312	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MDLIIIGM_00901	1.59e-38	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MDLIIIGM_00902	5.34e-164	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MDLIIIGM_00903	1.17e-23	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
MDLIIIGM_00904	4.93e-250	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDLIIIGM_00905	1.61e-207	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDLIIIGM_00906	3.2e-121	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
MDLIIIGM_00907	2.62e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDLIIIGM_00908	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MDLIIIGM_00909	4.21e-136	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MDLIIIGM_00910	1.82e-186	ymfH	-	-	S	-	-	-	Peptidase M16
MDLIIIGM_00911	5.2e-116	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MDLIIIGM_00912	7.25e-85	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
MDLIIIGM_00913	2.09e-111	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDLIIIGM_00914	1.84e-203	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDLIIIGM_00915	4.38e-256	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MDLIIIGM_00916	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDLIIIGM_00917	2e-287	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDLIIIGM_00918	2.19e-91	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDLIIIGM_00919	1.45e-193	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDLIIIGM_00920	2.88e-231	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MDLIIIGM_00921	5.96e-263	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDLIIIGM_00922	1.06e-20	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
MDLIIIGM_00923	5.6e-17	-	-	-	-	-	-	-	-
MDLIIIGM_00924	1.24e-183	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MDLIIIGM_00925	6.01e-55	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
MDLIIIGM_00926	8.83e-149	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MDLIIIGM_00927	1.52e-97	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDLIIIGM_00928	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDLIIIGM_00929	7.24e-71	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDLIIIGM_00930	8.95e-73	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
MDLIIIGM_00931	4.45e-55	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDLIIIGM_00932	3.96e-163	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDLIIIGM_00933	2.49e-97	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDLIIIGM_00934	1.07e-256	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MDLIIIGM_00935	1.05e-140	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDLIIIGM_00936	7.36e-238	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MDLIIIGM_00937	1.5e-109	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDLIIIGM_00938	7.08e-113	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDLIIIGM_00939	1.83e-172	-	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_00940	7.65e-185	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MDLIIIGM_00941	1.16e-147	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
MDLIIIGM_00942	4.96e-219	araT1	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDLIIIGM_00943	2.01e-110	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MDLIIIGM_00945	3.6e-57	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDLIIIGM_00946	3.81e-218	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MDLIIIGM_00947	6.27e-48	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
MDLIIIGM_00948	4.15e-34	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
MDLIIIGM_00949	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MDLIIIGM_00950	6.15e-51	-	-	-	-	-	-	-	-
MDLIIIGM_00951	3.55e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MDLIIIGM_00952	9.83e-91	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDLIIIGM_00953	5.16e-53	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MDLIIIGM_00956	4.92e-178	-	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDLIIIGM_00957	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDLIIIGM_00958	1.65e-272	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDLIIIGM_00959	1.79e-255	oatA	-	-	I	-	-	-	Acyltransferase
MDLIIIGM_00960	2.38e-22	-	-	-	-	-	-	-	-
MDLIIIGM_00962	8.7e-179	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDLIIIGM_00963	1.37e-127	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
MDLIIIGM_00964	8.24e-267	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MDLIIIGM_00965	3.03e-104	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDLIIIGM_00966	0.0	-	-	-	S	-	-	-	membrane
MDLIIIGM_00967	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MDLIIIGM_00968	6.91e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
MDLIIIGM_00969	1.52e-96	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
MDLIIIGM_00971	3.96e-156	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MDLIIIGM_00972	9.18e-248	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MDLIIIGM_00973	3.15e-60	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
MDLIIIGM_00976	1.91e-08	vpr	3.4.21.96	-	DO	ko:K01361,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	PA domain
MDLIIIGM_00980	1.98e-16	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MDLIIIGM_00982	1.66e-53	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
MDLIIIGM_00983	5.56e-61	hmpT	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MDLIIIGM_00984	2.05e-86	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MDLIIIGM_00986	7.86e-140	dat	2.6.1.21	-	EH	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	PFAM aminotransferase, class IV
MDLIIIGM_00987	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MDLIIIGM_00988	8.75e-60	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
MDLIIIGM_00989	3.21e-68	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MDLIIIGM_00990	1.8e-69	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
MDLIIIGM_00991	2.21e-73	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MDLIIIGM_00992	1.46e-42	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MDLIIIGM_00993	1.71e-97	azlC	-	-	E	-	-	-	branched-chain amino acid
MDLIIIGM_00994	2.29e-75	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MDLIIIGM_00995	3.49e-149	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MDLIIIGM_00996	7.76e-115	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MDLIIIGM_00997	7.5e-279	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDLIIIGM_00998	1.13e-278	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDLIIIGM_00999	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
MDLIIIGM_01000	2.67e-45	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MDLIIIGM_01001	2.17e-240	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
MDLIIIGM_01002	1.85e-96	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MDLIIIGM_01003	5.69e-142	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MDLIIIGM_01005	6.79e-263	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MDLIIIGM_01006	2.02e-78	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDLIIIGM_01007	3.63e-145	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
MDLIIIGM_01008	2.16e-192	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
MDLIIIGM_01009	1.4e-88	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
MDLIIIGM_01010	1.7e-66	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
MDLIIIGM_01011	3.08e-135	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MDLIIIGM_01012	6.59e-219	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MDLIIIGM_01013	4.4e-257	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
MDLIIIGM_01014	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDLIIIGM_01015	4.12e-236	noxE	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MDLIIIGM_01016	3.51e-58	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MDLIIIGM_01018	3.9e-134	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDLIIIGM_01019	7.11e-129	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_01020	3.36e-122	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MDLIIIGM_01021	3.75e-49	-	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_01022	6.4e-138	-	-	-	P	-	-	-	Integral membrane protein TerC family
MDLIIIGM_01023	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MDLIIIGM_01024	1.63e-85	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLIIIGM_01025	2.44e-235	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
MDLIIIGM_01026	5.09e-56	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
MDLIIIGM_01027	1.09e-121	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_01029	4.21e-53	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
MDLIIIGM_01030	1.64e-198	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MDLIIIGM_01031	1.57e-123	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDLIIIGM_01032	6.07e-199	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDLIIIGM_01033	3.93e-180	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDLIIIGM_01034	5e-45	-	-	-	-	-	-	-	-
MDLIIIGM_01035	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDLIIIGM_01036	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MDLIIIGM_01037	8.86e-84	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MDLIIIGM_01039	6.05e-94	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MDLIIIGM_01040	1.36e-78	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Possible lysine decarboxylase
MDLIIIGM_01041	5.36e-234	-	-	-	L	-	-	-	Probable transposase
MDLIIIGM_01042	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
MDLIIIGM_01043	1.97e-92	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
MDLIIIGM_01044	3.88e-160	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MDLIIIGM_01045	3.62e-130	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MDLIIIGM_01046	8.74e-104	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDLIIIGM_01047	4.97e-153	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
MDLIIIGM_01048	4.14e-138	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MDLIIIGM_01049	2.56e-32	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MDLIIIGM_01050	2.94e-242	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDLIIIGM_01051	3.13e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MDLIIIGM_01052	8.51e-115	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MDLIIIGM_01053	1.82e-67	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MDLIIIGM_01054	8.88e-14	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
MDLIIIGM_01055	2.75e-46	-	-	-	-	-	-	-	-
MDLIIIGM_01056	1.27e-132	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MDLIIIGM_01057	1.6e-126	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MDLIIIGM_01058	2.1e-139	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MDLIIIGM_01059	1.98e-71	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MDLIIIGM_01060	2.11e-131	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MDLIIIGM_01061	2.83e-196	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDLIIIGM_01062	2.46e-229	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MDLIIIGM_01063	7.43e-217	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDLIIIGM_01064	2.8e-189	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDLIIIGM_01065	3.07e-254	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDLIIIGM_01066	2.16e-277	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MDLIIIGM_01067	6.95e-112	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDLIIIGM_01068	2.49e-71	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDLIIIGM_01069	1.54e-81	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MDLIIIGM_01070	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MDLIIIGM_01071	1.02e-26	-	-	-	S	-	-	-	Cupredoxin-like domain
MDLIIIGM_01072	5.2e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
MDLIIIGM_01073	2.9e-189	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MDLIIIGM_01074	1.12e-28	-	-	-	K	-	-	-	transcriptional regulator
MDLIIIGM_01075	6.18e-97	-	-	-	S	-	-	-	intracellular protease amidase
MDLIIIGM_01076	1.16e-171	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MDLIIIGM_01077	4.75e-102	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MDLIIIGM_01078	1.69e-177	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MDLIIIGM_01079	2.4e-254	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MDLIIIGM_01080	7.24e-149	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MDLIIIGM_01081	2.46e-122	-	-	-	J	-	-	-	Aminoglycoside-2''-adenylyltransferase
MDLIIIGM_01082	5.22e-255	-	-	-	L	-	-	-	transposition, DNA-mediated
MDLIIIGM_01083	5.76e-221	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
MDLIIIGM_01084	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDLIIIGM_01085	5.74e-218	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDLIIIGM_01086	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MDLIIIGM_01087	3.65e-75	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDLIIIGM_01088	1.51e-165	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDLIIIGM_01089	7.4e-120	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MDLIIIGM_01090	1.16e-151	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDLIIIGM_01091	6.33e-74	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDLIIIGM_01092	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDLIIIGM_01093	2.85e-35	ylxQ	-	-	J	-	-	-	ribosomal protein
MDLIIIGM_01094	3.32e-53	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MDLIIIGM_01095	1.25e-216	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MDLIIIGM_01096	1.16e-85	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MDLIIIGM_01097	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDLIIIGM_01098	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDLIIIGM_01099	2.52e-196	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MDLIIIGM_01100	1.58e-131	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MDLIIIGM_01101	5.76e-134	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDLIIIGM_01102	8.26e-105	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDLIIIGM_01103	1.02e-147	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MDLIIIGM_01104	8.28e-64	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
MDLIIIGM_01105	6.13e-47	-	2.1.1.63	-	H	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDLIIIGM_01107	1.89e-291	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDLIIIGM_01108	1.48e-139	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MDLIIIGM_01109	1.73e-129	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MDLIIIGM_01110	3.3e-160	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MDLIIIGM_01111	1.45e-274	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MDLIIIGM_01112	7.97e-85	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDLIIIGM_01113	1.35e-59	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MDLIIIGM_01114	1e-247	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MDLIIIGM_01115	2.21e-125	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MDLIIIGM_01116	3.45e-130	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MDLIIIGM_01117	1.48e-36	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDLIIIGM_01118	4.26e-129	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MDLIIIGM_01119	1.29e-79	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MDLIIIGM_01120	9.26e-87	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDLIIIGM_01121	5.97e-49	-	-	-	-	-	-	-	-
MDLIIIGM_01123	3.18e-224	-	-	-	S	-	-	-	Protein of unknown function DUF262
MDLIIIGM_01124	2.17e-242	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MDLIIIGM_01125	8.94e-104	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDLIIIGM_01126	9.66e-80	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDLIIIGM_01127	9.88e-244	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MDLIIIGM_01128	6.58e-245	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MDLIIIGM_01129	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MDLIIIGM_01130	1.05e-225	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDLIIIGM_01132	5.27e-53	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDLIIIGM_01133	6.67e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
MDLIIIGM_01134	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MDLIIIGM_01135	2.26e-81	-	-	-	D	-	-	-	peptidase
MDLIIIGM_01136	1.33e-147	-	-	-	S	-	-	-	Glycosyl transferase family 2
MDLIIIGM_01137	2.13e-140	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
MDLIIIGM_01138	3.82e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDLIIIGM_01139	6.48e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDLIIIGM_01140	7.37e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MDLIIIGM_01141	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDLIIIGM_01142	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDLIIIGM_01143	5.91e-194	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDLIIIGM_01144	4.51e-27	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MDLIIIGM_01145	1.27e-201	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDLIIIGM_01146	4.47e-257	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDLIIIGM_01147	2.29e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MDLIIIGM_01148	8.2e-65	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDLIIIGM_01149	3.1e-137	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDLIIIGM_01150	2.06e-253	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
MDLIIIGM_01151	1.17e-152	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MDLIIIGM_01152	1.77e-67	-	-	-	K	-	-	-	LysR substrate binding domain
MDLIIIGM_01154	9.7e-84	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
MDLIIIGM_01155	3.46e-39	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MDLIIIGM_01156	3.93e-87	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MDLIIIGM_01157	4.08e-54	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MDLIIIGM_01158	1.05e-143	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDLIIIGM_01159	1.49e-93	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MDLIIIGM_01160	4.83e-258	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MDLIIIGM_01161	4.65e-193	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDLIIIGM_01162	2.68e-76	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MDLIIIGM_01163	4.37e-70	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
MDLIIIGM_01164	5.05e-115	nanK	-	-	GK	-	-	-	ROK family
MDLIIIGM_01165	4.39e-162	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MDLIIIGM_01166	5.09e-118	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MDLIIIGM_01167	2.33e-95	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MDLIIIGM_01168	1.31e-45	yphA	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
MDLIIIGM_01169	8.18e-272	potE	-	-	E	-	-	-	Amino Acid
MDLIIIGM_01170	5.75e-09	-	-	-	-	-	-	-	-
MDLIIIGM_01171	3.83e-43	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDLIIIGM_01172	3.84e-280	fusA1	-	-	J	-	-	-	elongation factor G
MDLIIIGM_01173	1.09e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
MDLIIIGM_01174	1.04e-59	-	-	-	L	-	-	-	PLD-like domain
MDLIIIGM_01175	7.27e-63	-	-	-	L	-	-	-	PLD-like domain
MDLIIIGM_01177	7.96e-143	-	-	-	L	-	-	-	Initiator Replication protein
MDLIIIGM_01178	1.88e-45	-	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
MDLIIIGM_01179	9.66e-180	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MDLIIIGM_01183	3.52e-42	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MDLIIIGM_01184	2.48e-114	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
MDLIIIGM_01185	8.25e-30	-	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	S-adenosylmethionine decarboxylase
MDLIIIGM_01186	2.93e-54	-	-	-	L	-	-	-	transposase activity
MDLIIIGM_01187	9.36e-166	-	-	-	S	-	-	-	Terminase-like family
MDLIIIGM_01188	1.38e-199	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MDLIIIGM_01191	3.2e-131	gpG	-	-	-	-	-	-	-
MDLIIIGM_01192	1.09e-46	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MDLIIIGM_01194	2.4e-42	-	-	-	-	-	-	-	-
MDLIIIGM_01195	5.15e-21	-	-	-	-	-	-	-	-
MDLIIIGM_01196	7.18e-59	-	-	-	-	-	-	-	-
MDLIIIGM_01199	3.29e-92	-	-	-	D	-	-	-	domain protein
MDLIIIGM_01200	3.63e-96	-	-	-	S	-	-	-	Phage tail protein
MDLIIIGM_01201	4.05e-94	-	-	-	M	-	-	-	Prophage endopeptidase tail
MDLIIIGM_01202	4.2e-122	-	-	-	M	-	-	-	Prophage endopeptidase tail
MDLIIIGM_01204	2.8e-30	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDLIIIGM_01206	3.52e-181	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDLIIIGM_01208	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MDLIIIGM_01209	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDLIIIGM_01210	1.97e-204	camS	-	-	S	-	-	-	sex pheromone
MDLIIIGM_01211	1.34e-50	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDLIIIGM_01212	7.24e-295	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDLIIIGM_01213	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDLIIIGM_01214	5.09e-183	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MDLIIIGM_01215	5.57e-271	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDLIIIGM_01217	0.0	mcrB	-	-	V	ko:K07452	-	ko00000,ko01000,ko02048	ATPase family associated with various cellular activities (AAA)
MDLIIIGM_01218	4.24e-213	mcrC	-	-	V	ko:K19147	-	ko00000,ko02048	Psort location Cytoplasmic, score
MDLIIIGM_01220	1.62e-13	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
MDLIIIGM_01221	3.51e-38	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MDLIIIGM_01222	1.1e-284	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDLIIIGM_01223	4.54e-87	ybbR	-	-	S	-	-	-	YbbR-like protein
MDLIIIGM_01224	1.95e-162	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDLIIIGM_01225	3.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
MDLIIIGM_01226	4.26e-146	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MDLIIIGM_01227	3.34e-90	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MDLIIIGM_01228	1e-72	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MDLIIIGM_01229	4.05e-180	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MDLIIIGM_01230	2.16e-134	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDLIIIGM_01231	1.68e-148	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MDLIIIGM_01232	1.37e-53	-	-	-	-	-	-	-	-
MDLIIIGM_01233	4.3e-91	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDLIIIGM_01234	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDLIIIGM_01235	1.19e-32	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MDLIIIGM_01236	4.45e-224	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MDLIIIGM_01237	5.39e-189	-	-	-	E	-	-	-	Major Facilitator Superfamily
MDLIIIGM_01238	9.3e-211	yclK	-	-	T	-	-	-	Histidine kinase
MDLIIIGM_01239	1.95e-134	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
MDLIIIGM_01240	3.5e-168	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDLIIIGM_01241	8.27e-221	-	-	-	C	-	-	-	FMN_bind
MDLIIIGM_01242	9.04e-70	oxyR5	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_01243	7e-201	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MDLIIIGM_01244	3.6e-250	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MDLIIIGM_01245	6.08e-95	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MDLIIIGM_01246	3.69e-166	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cobalamin-independent synthase, Catalytic domain
MDLIIIGM_01247	3.19e-114	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MDLIIIGM_01248	3.14e-104	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MDLIIIGM_01249	7.94e-14	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
MDLIIIGM_01250	6.98e-78	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
MDLIIIGM_01251	1.22e-199	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDLIIIGM_01253	2.37e-290	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDLIIIGM_01254	9.78e-82	-	-	-	C	-	-	-	FMN binding
MDLIIIGM_01255	1.24e-260	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MDLIIIGM_01256	9.07e-86	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MDLIIIGM_01257	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MDLIIIGM_01268	1.38e-165	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MDLIIIGM_01269	1.53e-234	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDLIIIGM_01270	1.12e-198	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MDLIIIGM_01271	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MDLIIIGM_01272	6.07e-152	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDLIIIGM_01274	6.91e-73	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MDLIIIGM_01275	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDLIIIGM_01276	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDLIIIGM_01277	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDLIIIGM_01278	2.03e-77	-	-	-	T	-	-	-	Universal stress protein family
MDLIIIGM_01279	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
MDLIIIGM_01280	2.65e-35	-	-	-	-	-	-	-	-
MDLIIIGM_01281	1.08e-251	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MDLIIIGM_01282	3.54e-140	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MDLIIIGM_01283	2.07e-106	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDLIIIGM_01284	3.31e-189	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
MDLIIIGM_01285	3.66e-184	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MDLIIIGM_01286	1.35e-19	-	-	-	M	-	-	-	COG0463, glycosyltransferases involved in cell wall biogenesis
MDLIIIGM_01287	6e-08	-	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
MDLIIIGM_01288	2.15e-36	cpsJ	-	-	M	-	-	-	Glycosyltransferase group 2 family protein
MDLIIIGM_01289	1.54e-82	nss	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MDLIIIGM_01290	2.77e-41	-	-	-	M	-	-	-	Glycosyl transferase, family 8
MDLIIIGM_01291	3.86e-66	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MDLIIIGM_01293	9.45e-27	arbY	-	-	M	-	-	-	family 8
MDLIIIGM_01294	2.72e-08	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.87
MDLIIIGM_01295	2.57e-77	nss	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MDLIIIGM_01296	9.26e-134	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MDLIIIGM_01297	2.54e-38	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MDLIIIGM_01298	3.86e-188	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MDLIIIGM_01299	1.04e-48	-	-	-	L	-	-	-	Helix-turn-helix domain
MDLIIIGM_01301	3.66e-101	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MDLIIIGM_01305	2.99e-08	-	-	-	S	-	-	-	peptidoglycan binding
MDLIIIGM_01307	1.55e-301	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDLIIIGM_01308	1.78e-21	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec system protein Asp3
MDLIIIGM_01309	1.36e-128	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system protein Asp2
MDLIIIGM_01310	6.57e-109	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
MDLIIIGM_01311	5.27e-75	secY2	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	SecY translocase
MDLIIIGM_01312	3.76e-172	-	-	-	S	-	-	-	interspecies interaction between organisms
MDLIIIGM_01313	2.25e-259	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	glycerol-3-phosphate transporter
MDLIIIGM_01314	2.26e-93	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDLIIIGM_01315	9.62e-189	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MDLIIIGM_01316	2.94e-147	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MDLIIIGM_01317	1.37e-40	-	-	-	S	-	-	-	YjbR
MDLIIIGM_01318	3.35e-100	yycI	-	-	S	-	-	-	YycH protein
MDLIIIGM_01319	1.07e-125	yycH	-	-	S	-	-	-	YycH protein
MDLIIIGM_01320	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDLIIIGM_01321	6.95e-151	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MDLIIIGM_01323	2.01e-185	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDLIIIGM_01324	2.6e-219	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MDLIIIGM_01326	1e-135	yxeH	-	-	S	-	-	-	hydrolase
MDLIIIGM_01327	1.29e-285	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
MDLIIIGM_01328	1.77e-268	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_01329	2.33e-41	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MDLIIIGM_01330	3.71e-217	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MDLIIIGM_01331	4.48e-32	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MDLIIIGM_01332	8.38e-80	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MDLIIIGM_01333	4.11e-175	-	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
MDLIIIGM_01334	2.01e-224	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MDLIIIGM_01335	2.89e-137	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MDLIIIGM_01336	7.89e-279	pepF	-	-	E	-	-	-	Oligopeptidase F
MDLIIIGM_01337	9.44e-121	yicL	-	-	EG	-	-	-	EamA-like transporter family
MDLIIIGM_01338	1.26e-89	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MDLIIIGM_01339	2.64e-212	-	-	-	S	-	-	-	Putative threonine/serine exporter
MDLIIIGM_01340	2.56e-140	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MDLIIIGM_01341	2.97e-12	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDLIIIGM_01342	2.59e-192	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MDLIIIGM_01343	7.35e-291	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
MDLIIIGM_01344	9.5e-136	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MDLIIIGM_01345	7.22e-282	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MDLIIIGM_01346	5.06e-290	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDLIIIGM_01347	5.01e-22	yneR	-	-	-	-	-	-	-
MDLIIIGM_01348	3.25e-307	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MDLIIIGM_01350	3.61e-79	uspA3	-	-	T	-	-	-	universal stress protein
MDLIIIGM_01352	2.92e-264	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
MDLIIIGM_01353	7.13e-150	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
MDLIIIGM_01354	2.34e-309	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
MDLIIIGM_01355	3.61e-84	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
MDLIIIGM_01356	1.75e-183	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDLIIIGM_01357	3.5e-18	-	-	-	-	-	-	-	-
MDLIIIGM_01358	1.53e-154	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MDLIIIGM_01359	4.98e-235	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDLIIIGM_01360	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDLIIIGM_01361	2.44e-49	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MDLIIIGM_01362	3.16e-78	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDLIIIGM_01363	7.02e-43	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MDLIIIGM_01364	3.67e-17	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MDLIIIGM_01365	7.68e-20	cvpA	-	-	S	-	-	-	Colicin V production protein
MDLIIIGM_01366	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDLIIIGM_01367	5.23e-54	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MDLIIIGM_01368	1.11e-35	hxlR	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MDLIIIGM_01369	1.11e-217	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDLIIIGM_01370	8.5e-132	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MDLIIIGM_01371	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MDLIIIGM_01372	4.18e-107	pncA	-	-	Q	-	-	-	isochorismatase
MDLIIIGM_01373	1.97e-82	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
MDLIIIGM_01374	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MDLIIIGM_01375	2.39e-108	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
MDLIIIGM_01376	4.28e-315	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MDLIIIGM_01377	1.55e-212	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MDLIIIGM_01380	3.52e-225	XK27_08315	-	-	M	-	-	-	Sulfatase
MDLIIIGM_01381	2.97e-72	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MDLIIIGM_01382	1.37e-65	-	-	-	L	-	-	-	Protein involved in initiation of plasmid replication
MDLIIIGM_01386	3.19e-59	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
MDLIIIGM_01387	1.6e-69	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MDLIIIGM_01388	1.39e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
MDLIIIGM_01389	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	Domain of unknown function DUF87
MDLIIIGM_01390	0.0	XK27_03330	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
MDLIIIGM_01391	1.43e-307	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
MDLIIIGM_01392	4.5e-255	XK26_06135	-	-	D	-	-	-	Plasmid recombination enzyme
MDLIIIGM_01396	4.31e-73	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MDLIIIGM_01397	1.38e-145	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDLIIIGM_01398	1.4e-238	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MDLIIIGM_01399	3.18e-115	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MDLIIIGM_01400	7.17e-192	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDLIIIGM_01401	3.13e-177	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDLIIIGM_01402	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDLIIIGM_01403	7.57e-153	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDLIIIGM_01404	8.22e-30	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDLIIIGM_01405	8.34e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MDLIIIGM_01406	5.39e-120	-	-	-	M	-	-	-	Phosphotransferase enzyme family
MDLIIIGM_01407	9.86e-36	spxA	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MDLIIIGM_01408	2.21e-236	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MDLIIIGM_01409	6.63e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MDLIIIGM_01410	2.29e-36	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MDLIIIGM_01411	2.82e-214	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MDLIIIGM_01412	1.14e-85	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MDLIIIGM_01413	2.25e-34	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDLIIIGM_01414	5.79e-84	licT	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
MDLIIIGM_01415	3.22e-161	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
MDLIIIGM_01417	8.96e-47	-	-	-	-	-	-	-	-
MDLIIIGM_01418	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MDLIIIGM_01419	3.83e-48	-	-	-	-	-	-	-	-
MDLIIIGM_01420	1.35e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDLIIIGM_01421	1.24e-237	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
MDLIIIGM_01422	5.12e-71	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MDLIIIGM_01423	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MDLIIIGM_01424	3.02e-227	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_01425	9.69e-90	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
MDLIIIGM_01428	1.91e-92	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MDLIIIGM_01429	8.46e-19	-	-	-	L	-	-	-	Belongs to the N(4) N(6)-methyltransferase family
MDLIIIGM_01430	1.76e-38	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MDLIIIGM_01433	4.52e-10	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
MDLIIIGM_01435	6.14e-32	-	-	-	L	-	-	-	Helix-turn-helix domain
MDLIIIGM_01436	5.29e-14	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MDLIIIGM_01438	6.99e-26	-	-	-	-	-	-	-	-
MDLIIIGM_01439	3.97e-80	-	-	-	S	-	-	-	Putative HNHc nuclease
MDLIIIGM_01440	1.75e-49	-	-	-	S	-	-	-	ERF superfamily
MDLIIIGM_01441	5.31e-10	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
MDLIIIGM_01445	1.52e-59	-	-	-	S	-	-	-	DNA binding
MDLIIIGM_01446	4.5e-23	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MDLIIIGM_01449	5.31e-18	-	-	-	-	-	-	-	-
MDLIIIGM_01451	4.5e-38	-	-	-	S	-	-	-	sequence-specific DNA binding
MDLIIIGM_01454	1.68e-17	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
MDLIIIGM_01455	1.16e-114	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MDLIIIGM_01456	1.71e-261	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDLIIIGM_01457	8.32e-21	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MDLIIIGM_01458	8.62e-123	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MDLIIIGM_01459	1.85e-40	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDLIIIGM_01460	9.96e-132	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDLIIIGM_01461	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDLIIIGM_01462	7.48e-284	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDLIIIGM_01463	6.96e-175	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MDLIIIGM_01464	1.4e-95	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDLIIIGM_01465	8.46e-293	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MDLIIIGM_01466	5.32e-200	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MDLIIIGM_01467	1.34e-113	-	-	-	S	-	-	-	Acyltransferase family
MDLIIIGM_01471	3.11e-252	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MDLIIIGM_01472	2.07e-52	-	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_01473	7.83e-144	-	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
MDLIIIGM_01478	4.73e-05	-	-	-	L	-	-	-	Transposase
MDLIIIGM_01491	2.89e-22	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
MDLIIIGM_01492	9.46e-50	-	-	-	-	-	-	-	-
MDLIIIGM_01497	1.41e-240	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MDLIIIGM_01498	3.91e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_01499	2.88e-56	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDLIIIGM_01500	2.25e-170	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MDLIIIGM_01501	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MDLIIIGM_01502	3.15e-56	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MDLIIIGM_01503	3.51e-80	-	-	-	D	-	-	-	Peptidase family M23
MDLIIIGM_01505	4.91e-172	tetA	-	-	EGP	ko:K08151,ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko01504,ko02000	Major facilitator Superfamily
MDLIIIGM_01506	1.24e-43	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MDLIIIGM_01507	3.61e-268	potE	-	-	E	-	-	-	Amino Acid
MDLIIIGM_01508	3.55e-61	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MDLIIIGM_01509	2.77e-19	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
MDLIIIGM_01510	8.77e-301	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDLIIIGM_01511	1.13e-248	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDLIIIGM_01512	1.8e-267	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MDLIIIGM_01513	2.88e-53	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MDLIIIGM_01514	1.32e-204	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDLIIIGM_01515	1.28e-76	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
MDLIIIGM_01516	2.41e-129	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MDLIIIGM_01517	6.67e-109	-	-	-	M	-	-	-	Rib/alpha-like repeat
MDLIIIGM_01518	8.57e-36	-	-	-	M	-	-	-	Rib/alpha-like repeat
MDLIIIGM_01520	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
MDLIIIGM_01522	1.38e-17	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MDLIIIGM_01523	1.52e-60	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MDLIIIGM_01524	7.6e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDLIIIGM_01525	2.84e-122	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MDLIIIGM_01526	8.05e-91	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
MDLIIIGM_01527	2.12e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MDLIIIGM_01528	1.73e-148	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MDLIIIGM_01529	2.95e-271	-	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MDLIIIGM_01530	8.49e-175	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MDLIIIGM_01531	1.11e-87	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MDLIIIGM_01532	2.2e-181	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Phage integrase family
MDLIIIGM_01533	7.75e-14	-	-	-	-	-	-	-	-
MDLIIIGM_01534	2.15e-43	-	-	-	-	-	-	-	-
MDLIIIGM_01536	1.49e-19	-	-	-	S	-	-	-	YjcQ protein
MDLIIIGM_01539	2.29e-128	bsh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
MDLIIIGM_01540	1.85e-89	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MDLIIIGM_01541	1.23e-99	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
MDLIIIGM_01542	4.33e-73	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDLIIIGM_01543	2.75e-67	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MDLIIIGM_01544	2.97e-101	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MDLIIIGM_01545	6.66e-126	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDLIIIGM_01546	3.52e-100	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MDLIIIGM_01547	3.37e-24	-	-	-	-	-	-	-	-
MDLIIIGM_01548	5.32e-18	-	-	-	-	-	-	-	-
MDLIIIGM_01549	3.73e-142	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MDLIIIGM_01550	5.49e-175	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDLIIIGM_01551	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
MDLIIIGM_01552	6.68e-64	-	-	-	S	-	-	-	VIT family
MDLIIIGM_01553	9.19e-304	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MDLIIIGM_01554	1.9e-52	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MDLIIIGM_01555	1.09e-181	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDLIIIGM_01556	3.71e-180	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MDLIIIGM_01557	1.5e-147	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MDLIIIGM_01558	2.72e-282	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
MDLIIIGM_01559	1.33e-179	-	-	-	P	-	-	-	Voltage gated chloride channel
MDLIIIGM_01560	3.83e-36	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDLIIIGM_01561	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MDLIIIGM_01562	7.3e-59	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MDLIIIGM_01563	5.97e-312	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MDLIIIGM_01564	5.36e-69	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MDLIIIGM_01566	1.1e-172	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MDLIIIGM_01567	9.61e-147	ddh	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MDLIIIGM_01568	2.33e-82	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
MDLIIIGM_01569	2.21e-47	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MDLIIIGM_01570	5.41e-173	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
MDLIIIGM_01571	1.93e-106	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
MDLIIIGM_01572	7.01e-57	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
MDLIIIGM_01573	2.84e-95	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MDLIIIGM_01574	1.37e-140	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
MDLIIIGM_01575	6.65e-54	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MDLIIIGM_01577	1.59e-11	-	-	-	-	-	-	-	-
MDLIIIGM_01582	1.7e-31	-	-	-	S	-	-	-	Phage minor capsid protein 2
MDLIIIGM_01583	6.18e-125	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MDLIIIGM_01584	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MDLIIIGM_01586	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
MDLIIIGM_01587	7.2e-89	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MDLIIIGM_01588	8.13e-13	blpT	-	-	-	-	-	-	-
MDLIIIGM_01589	1.94e-18	-	-	-	-	-	-	-	-
MDLIIIGM_01591	1.23e-37	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MDLIIIGM_01592	5.27e-123	-	-	-	-	-	-	-	-
MDLIIIGM_01593	1.89e-16	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
MDLIIIGM_01596	3.95e-32	-	-	-	S	-	-	-	Phage Mu protein F like protein
MDLIIIGM_01598	1.15e-236	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MDLIIIGM_01599	9.31e-103	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MDLIIIGM_01600	3.44e-54	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MDLIIIGM_01601	1.1e-30	-	-	-	S	-	-	-	Cytochrome B5
MDLIIIGM_01603	2.71e-80	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MDLIIIGM_01604	5.45e-243	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDLIIIGM_01605	9.74e-126	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MDLIIIGM_01606	7.08e-136	yueF	-	-	S	-	-	-	AI-2E family transporter
MDLIIIGM_01607	3.8e-201	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MDLIIIGM_01608	7.93e-146	tagH	3.6.3.40	-	GM	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MDLIIIGM_01609	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDLIIIGM_01610	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
MDLIIIGM_01612	5.38e-10	-	-	-	L	-	-	-	Transposase
MDLIIIGM_01613	1.77e-142	-	-	-	L	-	-	-	Transposase
MDLIIIGM_01614	8.61e-258	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDLIIIGM_01615	7.44e-153	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_01616	1.83e-41	-	-	-	-	-	-	-	-
MDLIIIGM_01617	2.05e-138	ampC	-	-	V	-	-	-	Beta-lactamase
MDLIIIGM_01618	9.35e-141	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
MDLIIIGM_01619	5.14e-278	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MDLIIIGM_01620	1.19e-111	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MDLIIIGM_01621	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDLIIIGM_01622	7.51e-114	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDLIIIGM_01623	5.45e-171	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDLIIIGM_01624	2.18e-129	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDLIIIGM_01625	4.84e-69	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MDLIIIGM_01626	6.35e-97	uspA	-	-	T	-	-	-	universal stress protein
MDLIIIGM_01628	5.46e-246	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MDLIIIGM_01629	1.46e-31	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MDLIIIGM_01630	5.9e-130	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDLIIIGM_01631	6.33e-73	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MDLIIIGM_01632	6.54e-223	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDLIIIGM_01633	1.02e-204	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MDLIIIGM_01634	1.44e-248	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDLIIIGM_01635	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDLIIIGM_01636	1.97e-20	-	-	-	D	-	-	-	nuclear chromosome segregation
MDLIIIGM_01638	1.86e-76	bcgIB	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K03427	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
MDLIIIGM_01639	1.21e-195	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MDLIIIGM_01640	3.19e-40	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDLIIIGM_01642	1.1e-74	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
MDLIIIGM_01647	1.53e-26	-	-	-	S	ko:K07065	-	ko00000	Toxic component of a toxin-antitoxin (TA) module. An RNase
MDLIIIGM_01648	1.16e-06	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
MDLIIIGM_01649	3.14e-34	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MDLIIIGM_01651	2.83e-26	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
MDLIIIGM_01652	1.4e-141	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	Domain of unknown function (DUF4162)
MDLIIIGM_01653	3.32e-105	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type Na efflux pump, permease component
MDLIIIGM_01654	1.2e-110	-	-	-	EG	-	-	-	EamA-like transporter family
MDLIIIGM_01655	2.25e-88	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MDLIIIGM_01656	8.2e-108	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_01657	2.76e-128	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
MDLIIIGM_01658	9.8e-87	-	-	-	S	-	-	-	AAA ATPase domain
MDLIIIGM_01660	7.41e-17	-	-	-	-	-	-	-	-
MDLIIIGM_01661	2.24e-23	-	-	-	L	-	-	-	nuclease
MDLIIIGM_01662	5.12e-36	-	-	-	S	-	-	-	Short C-terminal domain
MDLIIIGM_01663	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MDLIIIGM_01664	2.26e-139	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MDLIIIGM_01665	8.74e-225	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDLIIIGM_01666	1.26e-207	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MDLIIIGM_01667	1.15e-250	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MDLIIIGM_01668	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MDLIIIGM_01669	2.7e-130	-	-	-	G	-	-	-	MucBP domain
MDLIIIGM_01670	1.18e-29	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
MDLIIIGM_01672	7.15e-161	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MDLIIIGM_01673	9.11e-195	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MDLIIIGM_01674	2.05e-191	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MDLIIIGM_01675	2.07e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDLIIIGM_01677	2.76e-175	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
MDLIIIGM_01678	1.19e-231	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDLIIIGM_01679	1.99e-264	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MDLIIIGM_01680	9.95e-165	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDLIIIGM_01681	4.33e-298	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDLIIIGM_01682	8.83e-197	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MDLIIIGM_01683	7e-134	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MDLIIIGM_01684	4.59e-121	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MDLIIIGM_01685	4.26e-277	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
MDLIIIGM_01686	1.34e-254	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDLIIIGM_01687	5.29e-178	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MDLIIIGM_01688	1.06e-243	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MDLIIIGM_01690	5.06e-14	-	-	-	S	-	-	-	Bacteriophage holin
MDLIIIGM_01691	2.32e-165	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
MDLIIIGM_01695	1.33e-108	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDLIIIGM_01696	2.27e-87	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MDLIIIGM_01697	1.97e-56	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MDLIIIGM_01698	7.45e-220	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDLIIIGM_01699	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDLIIIGM_01700	1.11e-231	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDLIIIGM_01701	1.22e-175	-	-	-	V	-	-	-	Pfam:Methyltransf_26
MDLIIIGM_01704	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDLIIIGM_01705	1.35e-262	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDLIIIGM_01707	3.27e-26	-	-	-	-	-	-	-	-
MDLIIIGM_01709	3.07e-25	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MDLIIIGM_01710	1.29e-08	ansR	-	-	K	-	-	-	transcriptional
MDLIIIGM_01711	4.52e-153	-	-	-	K	-	-	-	Transcriptional regulator
MDLIIIGM_01716	5.38e-101	-	-	-	S	-	-	-	Siphovirus Gp157
MDLIIIGM_01717	1.18e-309	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDLIIIGM_01718	1.26e-148	-	-	-	L	-	-	-	AAA domain
MDLIIIGM_01719	9.92e-110	-	-	-	-	-	-	-	-
MDLIIIGM_01720	1.1e-181	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
MDLIIIGM_01721	7.38e-292	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
MDLIIIGM_01722	5.16e-66	-	-	-	S	-	-	-	VRR_NUC
MDLIIIGM_01726	1.6e-36	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
MDLIIIGM_01730	6.46e-114	-	-	-	L	-	-	-	HNH nucleases
MDLIIIGM_01731	3.95e-78	-	-	-	L	-	-	-	Phage terminase, small subunit
MDLIIIGM_01732	0.0	-	-	-	S	-	-	-	Phage Terminase
MDLIIIGM_01734	9.49e-262	-	-	-	S	-	-	-	Phage portal protein
MDLIIIGM_01735	3.62e-155	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MDLIIIGM_01736	1.51e-279	-	-	-	S	-	-	-	Phage capsid family
MDLIIIGM_01737	1.08e-29	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MDLIIIGM_01738	6.36e-78	-	-	-	S	-	-	-	Phage head-tail joining protein
MDLIIIGM_01739	1.13e-84	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
MDLIIIGM_01740	1.46e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
MDLIIIGM_01741	5.19e-157	-	-	-	S	-	-	-	Phage tail tube protein
MDLIIIGM_01742	1.36e-74	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
MDLIIIGM_01744	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MDLIIIGM_01745	6.98e-183	-	-	-	S	-	-	-	Phage tail protein
MDLIIIGM_01746	0.0	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
MDLIIIGM_01749	8.92e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
MDLIIIGM_01754	7.28e-27	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MDLIIIGM_01755	8.3e-146	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MDLIIIGM_01757	3.72e-236	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDLIIIGM_01758	4.18e-18	-	-	-	S	-	-	-	ASCH
MDLIIIGM_01759	3.9e-91	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase, peptidase S26
MDLIIIGM_01760	4.82e-147	-	-	-	S	-	-	-	EDD domain protein, DegV family
MDLIIIGM_01761	4.96e-146	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
MDLIIIGM_01764	3.74e-75	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
MDLIIIGM_01766	6.51e-33	-	-	-	S	-	-	-	COG0433 Predicted ATPase
MDLIIIGM_01767	6.3e-242	-	-	-	S	-	-	-	COG0433 Predicted ATPase
MDLIIIGM_01768	3.91e-54	-	-	-	-	-	-	-	-
MDLIIIGM_01771	5.42e-167	-	-	-	NU	-	-	-	StbA protein
MDLIIIGM_01772	1.42e-108	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MDLIIIGM_01773	2.33e-29	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
MDLIIIGM_01785	4.04e-55	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
MDLIIIGM_01787	1.44e-67	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
MDLIIIGM_01788	1.22e-33	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDLIIIGM_01791	3.95e-54	-	-	-	M	-	-	-	hmm tigr01076
MDLIIIGM_01792	1.25e-104	-	-	-	M	-	-	-	Gram-positive pilin backbone subunit 2, Cna-B-like domain
MDLIIIGM_01796	6.04e-70	-	-	-	S	-	-	-	N-acetylmuramoyl-L-alanine amidase activity
MDLIIIGM_01797	1.82e-49	-	-	-	-	-	-	-	-
MDLIIIGM_01798	4.68e-119	dgk1	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
MDLIIIGM_01799	1.89e-75	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDLIIIGM_01800	3.15e-200	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDLIIIGM_01801	3.59e-285	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDLIIIGM_01802	4.68e-137	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDLIIIGM_01804	1.46e-141	csrR	-	-	K	-	-	-	response regulator
MDLIIIGM_01805	1.09e-218	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MDLIIIGM_01806	4.06e-30	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
MDLIIIGM_01807	2.95e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDLIIIGM_01808	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDLIIIGM_01809	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDLIIIGM_01810	4.67e-117	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MDLIIIGM_01811	7.86e-106	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MDLIIIGM_01812	1.21e-145	vanR	-	-	K	-	-	-	response regulator
MDLIIIGM_01813	5.29e-191	hpk31	-	-	T	-	-	-	Histidine kinase
MDLIIIGM_01820	1.74e-103	-	-	-	K	-	-	-	Penicillinase repressor
MDLIIIGM_01821	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	haloacid dehalogenase-like hydrolase
MDLIIIGM_01822	1.4e-53	-	-	-	S	ko:K08982	-	ko00000	membrane protein (DUF2078)
MDLIIIGM_01823	5.25e-22	-	-	-	S	-	-	-	Domain of unknown function DUF302
MDLIIIGM_01824	1.61e-44	-	-	-	S	-	-	-	Domain of unknown function DUF302
MDLIIIGM_01825	3.53e-230	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MDLIIIGM_01826	6.22e-81	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
MDLIIIGM_01827	3.29e-224	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDLIIIGM_01828	2.28e-283	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDLIIIGM_01829	1.5e-40	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDLIIIGM_01830	1.44e-179	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDLIIIGM_01832	5e-64	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MDLIIIGM_01833	3.44e-169	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MDLIIIGM_01834	2.96e-75	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MDLIIIGM_01835	1.19e-259	-	-	-	L	ko:K04763	-	ko00000,ko03036	similarity to EGAD 7942
MDLIIIGM_01836	0.0	-	-	-	L	-	-	-	similarity to EGAD 8390
MDLIIIGM_01837	5.94e-75	-	-	-	S	-	-	-	similarity to EGAD 6135
MDLIIIGM_01838	9.06e-186	-	-	-	S	ko:K19279	-	ko00000,ko01000,ko01504	Domain of unknown function (DUF4111)
MDLIIIGM_01839	5.08e-111	ermA	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
MDLIIIGM_01840	2.33e-124	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MDLIIIGM_01841	1.39e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDLIIIGM_01842	2.96e-57	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDLIIIGM_01843	2.82e-74	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDLIIIGM_01844	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDLIIIGM_01845	9.43e-181	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDLIIIGM_01846	8.04e-313	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDLIIIGM_01847	6.22e-70	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MDLIIIGM_01848	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDLIIIGM_01849	3.45e-36	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
MDLIIIGM_01850	2.92e-164	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDLIIIGM_01851	2.61e-163	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MDLIIIGM_01852	5.16e-203	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MDLIIIGM_01853	1.8e-33	-	-	-	L	-	-	-	Transposase
MDLIIIGM_01855	1.98e-80	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MDLIIIGM_01856	2.94e-91	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MDLIIIGM_01857	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MDLIIIGM_01858	2.11e-122	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDLIIIGM_01859	6e-76	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDLIIIGM_01861	3.59e-60	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
MDLIIIGM_01862	7.92e-69	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDLIIIGM_01863	1.49e-208	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MDLIIIGM_01864	4.78e-86	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter
MDLIIIGM_01865	1.03e-129	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MDLIIIGM_01866	8.21e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MDLIIIGM_01867	3.68e-151	ytbE	-	-	S	-	-	-	reductase
MDLIIIGM_01868	1.84e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDLIIIGM_01869	4.68e-203	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MDLIIIGM_01870	5.53e-49	-	-	-	M	-	-	-	LysM domain
MDLIIIGM_01871	1.38e-25	-	-	-	P	-	-	-	Rhodanese Homology Domain
MDLIIIGM_01872	1.8e-67	-	-	-	M	-	-	-	LysM domain protein
MDLIIIGM_01873	2.6e-114	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
MDLIIIGM_01874	0.000269	-	-	-	C	-	-	-	galactose-1-phosphate uridylyltransferase
MDLIIIGM_01875	3.99e-91	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
MDLIIIGM_01876	1.21e-20	-	-	-	-	-	-	-	-
MDLIIIGM_01878	5.56e-89	-	-	-	-	-	-	-	-
MDLIIIGM_01879	1.94e-124	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
MDLIIIGM_01880	3.66e-224	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MDLIIIGM_01881	5.15e-155	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
MDLIIIGM_01882	4.03e-102	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDLIIIGM_01883	6.04e-275	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDLIIIGM_01884	4.82e-49	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDLIIIGM_01885	2.77e-75	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDLIIIGM_01886	3.83e-79	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDLIIIGM_01887	2.3e-127	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MDLIIIGM_01888	6.23e-76	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDLIIIGM_01889	1.16e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF441)
MDLIIIGM_01890	3.06e-159	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MDLIIIGM_01891	1.39e-142	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MDLIIIGM_01892	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MDLIIIGM_01893	1.17e-98	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDLIIIGM_01894	5.33e-237	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MDLIIIGM_01895	3.94e-84	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MDLIIIGM_01896	2.09e-246	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
MDLIIIGM_01898	1.59e-91	-	-	-	M	-	-	-	GNAT acetyltransferase
MDLIIIGM_01899	1.64e-87	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MDLIIIGM_01900	1.34e-73	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MDLIIIGM_01901	6.87e-103	-	-	-	F	-	-	-	Hydrolase, nudix family
MDLIIIGM_01903	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
MDLIIIGM_01904	9.72e-259	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
MDLIIIGM_01905	1.22e-92	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I Restriction
MDLIIIGM_01906	1.9e-166	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_01907	7.21e-105	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MDLIIIGM_01908	6.98e-96	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MDLIIIGM_01909	4.22e-87	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLIIIGM_01910	1.33e-135	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MDLIIIGM_01911	4.75e-215	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MDLIIIGM_01912	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MDLIIIGM_01913	6.27e-264	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDLIIIGM_01914	7.63e-237	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDLIIIGM_01915	2.54e-276	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MDLIIIGM_01916	5.3e-80	-	-	-	S	-	-	-	Helix-turn-helix domain
MDLIIIGM_01917	2.63e-155	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MDLIIIGM_01918	9.02e-28	-	-	-	M	-	-	-	Lysin motif
MDLIIIGM_01919	1.02e-111	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MDLIIIGM_01920	7.33e-107	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
MDLIIIGM_01921	5.08e-197	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MDLIIIGM_01922	2.42e-88	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDLIIIGM_01923	4.18e-40	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MDLIIIGM_01924	4.63e-199	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDLIIIGM_01925	6.69e-115	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MDLIIIGM_01927	1.25e-275	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDLIIIGM_01928	1.94e-222	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MDLIIIGM_01929	4.73e-40	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDLIIIGM_01930	3.32e-191	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDLIIIGM_01931	1.66e-76	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphatase family
MDLIIIGM_01932	3.19e-220	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MDLIIIGM_01933	3.35e-288	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MDLIIIGM_01934	2.02e-48	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDLIIIGM_01935	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDLIIIGM_01936	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDLIIIGM_01937	1.38e-106	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDLIIIGM_01938	6.49e-53	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
MDLIIIGM_01945	2.61e-21	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MDLIIIGM_01946	7.49e-262	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MDLIIIGM_01947	4.6e-145	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MDLIIIGM_01948	7.07e-53	-	-	-	K	-	-	-	LytTr DNA-binding domain
MDLIIIGM_01950	1.31e-191	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MDLIIIGM_01951	7.99e-16	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
MDLIIIGM_01952	2.97e-132	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MDLIIIGM_01953	4.87e-112	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDLIIIGM_01954	3.1e-168	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDLIIIGM_01955	1.9e-31	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
MDLIIIGM_01956	3.15e-114	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MDLIIIGM_01957	1.92e-176	-	-	-	E	-	-	-	Beta-eliminating lyase
MDLIIIGM_01958	5.91e-61	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MDLIIIGM_01961	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDLIIIGM_01962	5.69e-49	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MDLIIIGM_01963	1.5e-22	-	-	-	-	-	-	-	-
MDLIIIGM_01964	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MDLIIIGM_01966	1.06e-211	-	-	-	S	-	-	-	Terminase-like family
MDLIIIGM_01968	1.75e-161	-	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
MDLIIIGM_01969	7.24e-121	-	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
MDLIIIGM_01970	5.94e-16	-	-	-	L	ko:K07498	-	ko00000	Transposase
MDLIIIGM_01971	8.61e-67	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
MDLIIIGM_01972	3.22e-140	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MDLIIIGM_01973	1.23e-34	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
MDLIIIGM_01974	1.79e-100	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MDLIIIGM_01976	1.56e-48	-	-	-	S	-	-	-	PD-(D/E)XK nuclease superfamily
MDLIIIGM_01986	2.15e-59	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
MDLIIIGM_01987	2.3e-78	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
MDLIIIGM_01988	1.17e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MDLIIIGM_01989	3.65e-74	napB	-	-	K	-	-	-	transcriptional
MDLIIIGM_01990	1.13e-89	mleR	-	-	K	-	-	-	LysR family
MDLIIIGM_01991	9.73e-313	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
MDLIIIGM_01992	3.55e-161	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
MDLIIIGM_01993	4.02e-82	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
MDLIIIGM_01994	7.37e-77	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MDLIIIGM_01995	5.57e-96	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDLIIIGM_01996	6.35e-254	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MDLIIIGM_01997	6.03e-51	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MDLIIIGM_01998	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MDLIIIGM_01999	5.56e-124	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MDLIIIGM_02000	1.79e-148	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDLIIIGM_02001	1.13e-116	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MDLIIIGM_02002	5.17e-228	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MDLIIIGM_02003	1.96e-54	-	-	-	-	-	-	-	-
MDLIIIGM_02004	1.32e-41	-	-	-	K	-	-	-	GNAT family
MDLIIIGM_02005	5.6e-263	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MDLIIIGM_02006	5.08e-278	gdhA	1.4.1.3, 1.4.1.4	-	E	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	ko00000,ko00001,ko00002,ko01000,ko04147	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MDLIIIGM_02007	1.47e-45	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MDLIIIGM_02008	1.03e-272	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MDLIIIGM_02009	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDLIIIGM_02010	2.38e-209	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDLIIIGM_02011	7.84e-157	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
MDLIIIGM_02012	6.37e-244	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
MDLIIIGM_02013	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDLIIIGM_02014	9.89e-215	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
MDLIIIGM_02015	1.13e-32	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
MDLIIIGM_02016	3.09e-160	mocA	-	-	S	-	-	-	Oxidoreductase
MDLIIIGM_02017	9.82e-202	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MDLIIIGM_02020	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MDLIIIGM_02021	1.64e-126	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MDLIIIGM_02022	3.51e-270	-	-	-	G	ko:K16211	-	ko00000,ko02000	Transporter, major facilitator family protein
MDLIIIGM_02023	9.55e-96	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MDLIIIGM_02024	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MDLIIIGM_02025	1.29e-109	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MDLIIIGM_02026	1.16e-313	-	-	-	E	-	-	-	Amino acid permease
MDLIIIGM_02027	1.49e-11	-	-	-	E	-	-	-	Amino acid permease
MDLIIIGM_02028	7.04e-229	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
MDLIIIGM_02029	5.08e-213	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDLIIIGM_02030	4.88e-90	-	-	-	K	-	-	-	Sugar-specific transcriptional regulator TrmB
MDLIIIGM_02031	4.15e-47	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
MDLIIIGM_02032	2.54e-232	-	-	-	L	-	-	-	Probable transposase
MDLIIIGM_02033	3.37e-27	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MDLIIIGM_02034	4.44e-98	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MDLIIIGM_02035	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MDLIIIGM_02036	3.97e-69	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MDLIIIGM_02037	2.04e-69	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MDLIIIGM_02038	3.03e-183	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MDLIIIGM_02039	5.63e-195	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MDLIIIGM_02040	2.24e-16	-	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	Lysin motif
MDLIIIGM_02041	3.4e-119	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MDLIIIGM_02042	2.17e-165	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDLIIIGM_02043	3.41e-214	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDLIIIGM_02044	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MDLIIIGM_02045	4.07e-213	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MDLIIIGM_02046	2.2e-271	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDLIIIGM_02047	1.88e-18	-	-	-	-	-	-	-	-
MDLIIIGM_02048	2.45e-132	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_02049	3.96e-125	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MDLIIIGM_02050	4.89e-111	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDLIIIGM_02051	1.88e-104	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MDLIIIGM_02052	4.7e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MDLIIIGM_02053	1.55e-37	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MDLIIIGM_02054	3.02e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MDLIIIGM_02057	8.46e-72	-	-	-	V	-	-	-	endonuclease activity
MDLIIIGM_02060	5.54e-83	-	-	-	L	-	-	-	Replication protein
MDLIIIGM_02066	4.52e-131	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDLIIIGM_02067	3.24e-90	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MDLIIIGM_02069	4.29e-115	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
MDLIIIGM_02070	3.45e-198	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
MDLIIIGM_02071	1.8e-56	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDLIIIGM_02072	8.28e-75	-	-	-	-	-	-	-	-
MDLIIIGM_02073	1.06e-28	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
MDLIIIGM_02080	1.27e-52	-	-	-	S	-	-	-	Bacteriophage holin family
MDLIIIGM_02085	1.55e-05	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
MDLIIIGM_02088	3.6e-115	-	-	-	M	-	-	-	Prophage endopeptidase tail
MDLIIIGM_02090	4.38e-111	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MDLIIIGM_02091	3.88e-50	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
MDLIIIGM_02093	6.69e-50	-	-	-	N	-	-	-	domain, Protein
MDLIIIGM_02096	1.07e-38	-	-	-	S	-	-	-	Minor capsid protein
MDLIIIGM_02098	2.49e-123	-	-	-	S	-	-	-	T=7 icosahedral viral capsid
MDLIIIGM_02099	9.27e-30	-	-	-	S	-	-	-	Phage minor structural protein GP20
MDLIIIGM_02102	4.09e-113	-	-	-	S	-	-	-	Phage minor capsid protein 2
MDLIIIGM_02103	1.09e-176	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
MDLIIIGM_02104	2.77e-207	-	-	-	S	-	-	-	Pfam:Terminase_3C
MDLIIIGM_02105	1.08e-27	-	-	-	-	-	-	-	-
MDLIIIGM_02114	5.62e-59	-	-	-	S	-	-	-	magnesium ion binding
MDLIIIGM_02115	0.0	-	-	-	L	-	-	-	Primase C terminal 2 (PriCT-2)
MDLIIIGM_02116	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MDLIIIGM_02117	3.03e-104	-	-	-	-	-	-	-	-
MDLIIIGM_02118	1.15e-52	-	-	-	-	-	-	-	-
MDLIIIGM_02119	1.52e-64	-	-	-	-	-	-	-	-
MDLIIIGM_02120	5.21e-134	-	-	-	S	-	-	-	AAA domain
MDLIIIGM_02121	3.44e-206	-	-	-	D	-	-	-	AAA domain
MDLIIIGM_02127	1.93e-26	-	-	-	-	-	-	-	-
MDLIIIGM_02128	1.65e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
MDLIIIGM_02129	3.84e-57	-	-	-	K	ko:K07727	-	ko00000,ko03000	addiction module antidote protein HigA
MDLIIIGM_02130	6.75e-49	-	-	-	E	-	-	-	IrrE N-terminal-like domain
MDLIIIGM_02131	2.16e-33	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MDLIIIGM_02132	7.96e-39	-	-	-	-	-	-	-	-
MDLIIIGM_02133	6.66e-98	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MDLIIIGM_02134	7.31e-164	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDLIIIGM_02135	2e-171	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MDLIIIGM_02136	6.9e-37	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
MDLIIIGM_02137	4.86e-120	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MDLIIIGM_02138	3.48e-114	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MDLIIIGM_02139	8.93e-35	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MDLIIIGM_02140	3.18e-73	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MDLIIIGM_02141	3.25e-153	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MDLIIIGM_02142	1.86e-103	-	-	-	H	-	-	-	Nodulation protein S (NodS)
MDLIIIGM_02143	4.81e-66	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDLIIIGM_02144	1.33e-88	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MDLIIIGM_02145	7.07e-99	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDLIIIGM_02146	9.56e-41	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
MDLIIIGM_02147	5.09e-230	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MDLIIIGM_02148	2.34e-91	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MDLIIIGM_02149	5.01e-69	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDLIIIGM_02150	4.44e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MDLIIIGM_02151	1.25e-102	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDLIIIGM_02152	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDLIIIGM_02153	5.69e-137	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MDLIIIGM_02154	4.39e-96	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
MDLIIIGM_02155	1.04e-85	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDLIIIGM_02156	8.69e-62	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDLIIIGM_02157	1.71e-136	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDLIIIGM_02158	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDLIIIGM_02159	4.23e-56	-	-	-	S	-	-	-	regulation of transcription, DNA-dependent
MDLIIIGM_02161	1.89e-89	-	-	-	S	-	-	-	peptidoglycan catabolic process
MDLIIIGM_02162	1.68e-305	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
MDLIIIGM_02163	5.17e-167	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MDLIIIGM_02164	3.35e-65	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDLIIIGM_02165	3.53e-94	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MDLIIIGM_02166	2.86e-24	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MDLIIIGM_02167	1.08e-117	dedA	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MDLIIIGM_02168	1.63e-118	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MDLIIIGM_02169	2.55e-65	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
MDLIIIGM_02170	5.74e-88	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDLIIIGM_02171	4.31e-127	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MDLIIIGM_02172	1.15e-163	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MDLIIIGM_02173	2.45e-38	pac	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MDLIIIGM_02175	2.84e-197	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MDLIIIGM_02176	1.94e-98	-	-	-	K	-	-	-	sequence-specific DNA binding
MDLIIIGM_02177	3.81e-49	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MDLIIIGM_02178	1.29e-200	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MDLIIIGM_02179	1.06e-76	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MDLIIIGM_02182	6.43e-69	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Thymidine kinase
MDLIIIGM_02184	1.11e-64	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDLIIIGM_02185	6.43e-80	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
MDLIIIGM_02186	3.28e-67	-	-	-	-	-	-	-	-
MDLIIIGM_02187	1.13e-103	-	-	-	L	-	-	-	Transposase, IS116 IS110 IS902 family
MDLIIIGM_02188	4.44e-41	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MDLIIIGM_02189	1.67e-123	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDLIIIGM_02190	2.54e-170	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDLIIIGM_02191	1.77e-33	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MDLIIIGM_02192	7.98e-69	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
MDLIIIGM_02193	2.14e-99	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MDLIIIGM_02195	7.2e-142	ydhF	-	-	S	-	-	-	Aldo keto reductase
MDLIIIGM_02196	6.42e-32	-	-	-	K	-	-	-	regulatory protein
MDLIIIGM_02197	2.42e-169	-	-	-	C	-	-	-	Aldo keto reductase
MDLIIIGM_02198	7.15e-72	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDLIIIGM_02199	1.36e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDLIIIGM_02200	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MDLIIIGM_02201	2.05e-167	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDLIIIGM_02202	1.85e-136	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDLIIIGM_02203	1.89e-142	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDLIIIGM_02204	5.44e-87	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MDLIIIGM_02206	1.87e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MDLIIIGM_02207	5.93e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MDLIIIGM_02208	2.08e-148	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDLIIIGM_02211	3.08e-126	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MDLIIIGM_02212	3.47e-106	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MDLIIIGM_02213	2.22e-114	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MDLIIIGM_02214	6.17e-160	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDLIIIGM_02215	7.32e-101	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDLIIIGM_02216	3.11e-108	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDLIIIGM_02217	5.71e-72	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MDLIIIGM_02218	4.9e-300	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MDLIIIGM_02219	9.06e-181	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MDLIIIGM_02220	1.35e-46	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MDLIIIGM_02221	2.58e-269	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MDLIIIGM_02222	5.52e-121	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
MDLIIIGM_02223	2.07e-155	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MDLIIIGM_02224	6.58e-172	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MDLIIIGM_02225	3.76e-143	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDLIIIGM_02226	1.79e-134	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MDLIIIGM_02227	1.24e-186	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MDLIIIGM_02228	1.71e-90	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MDLIIIGM_02229	7.31e-63	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MDLIIIGM_02230	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MDLIIIGM_02231	4.58e-73	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MDLIIIGM_02232	6.94e-28	-	-	-	-	-	-	-	-
MDLIIIGM_02234	7.02e-157	-	-	-	K	-	-	-	LysR substrate binding domain
MDLIIIGM_02235	1.38e-242	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDLIIIGM_02236	1.91e-17	-	-	-	S	-	-	-	Acyltransferase family
MDLIIIGM_02237	1.2e-83	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family