ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MHCKMFAJ_00004 1.89e-29 - - - - - - - -
MHCKMFAJ_00020 1.98e-10 - - - M - - - Rib/alpha-like repeat
MHCKMFAJ_00021 1.98e-10 - - - M - - - Rib/alpha-like repeat
MHCKMFAJ_00022 2.51e-67 - - - L ko:K07491 - ko00000 Transposase IS200 like
MHCKMFAJ_00023 3.23e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHCKMFAJ_00024 7.55e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MHCKMFAJ_00025 7.88e-87 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MHCKMFAJ_00026 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MHCKMFAJ_00027 4.07e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHCKMFAJ_00028 5.31e-72 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
MHCKMFAJ_00029 2.71e-106 lysR5 - - K - - - LysR substrate binding domain
MHCKMFAJ_00030 3.86e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
MHCKMFAJ_00031 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
MHCKMFAJ_00032 6.86e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHCKMFAJ_00033 7.34e-285 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHCKMFAJ_00034 8.89e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCKMFAJ_00035 4.78e-207 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
MHCKMFAJ_00036 6.81e-103 - - - S - - - L,D-transpeptidase catalytic domain
MHCKMFAJ_00037 3.67e-172 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MHCKMFAJ_00038 2.47e-185 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MHCKMFAJ_00039 1.86e-35 yuxO - - Q - - - Thioesterase superfamily
MHCKMFAJ_00040 1.68e-69 - - - F - - - Glutamine amidotransferase class-I
MHCKMFAJ_00041 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MHCKMFAJ_00042 2.47e-146 degV - - S - - - EDD domain protein, DegV family
MHCKMFAJ_00043 3.6e-293 cadA - - P - - - P-type ATPase
MHCKMFAJ_00044 0.0 - - - E - - - Amino acid permease
MHCKMFAJ_00045 2.22e-108 - - - S - - - Membrane
MHCKMFAJ_00046 3.27e-57 cps3F - - - - - - -
MHCKMFAJ_00047 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MHCKMFAJ_00048 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MHCKMFAJ_00049 1.2e-112 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MHCKMFAJ_00050 7.63e-279 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MHCKMFAJ_00051 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MHCKMFAJ_00052 2.52e-17 - - - - - - - -
MHCKMFAJ_00053 1.57e-77 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MHCKMFAJ_00054 2.36e-72 - - - S - - - Protein of unknown function (DUF975)
MHCKMFAJ_00055 9.52e-187 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MHCKMFAJ_00056 4.36e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MHCKMFAJ_00057 6.36e-229 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHCKMFAJ_00058 6.13e-212 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MHCKMFAJ_00059 2.47e-222 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MHCKMFAJ_00062 9.21e-45 - - - S - - - Protein of unknown function (DUF4256)
MHCKMFAJ_00063 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHCKMFAJ_00064 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_00065 1.53e-192 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHCKMFAJ_00067 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MHCKMFAJ_00068 1.29e-215 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHCKMFAJ_00069 2.34e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
MHCKMFAJ_00070 4.37e-106 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MHCKMFAJ_00071 2.84e-107 - - - C - - - nitroreductase
MHCKMFAJ_00072 3.22e-168 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MHCKMFAJ_00073 7.43e-119 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_00074 5.34e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHCKMFAJ_00075 4.23e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHCKMFAJ_00076 1.03e-176 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MHCKMFAJ_00078 1.55e-301 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHCKMFAJ_00079 1.78e-21 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
MHCKMFAJ_00080 1.36e-128 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
MHCKMFAJ_00081 6.57e-109 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
MHCKMFAJ_00082 5.27e-75 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecY translocase
MHCKMFAJ_00083 3.76e-172 - - - S - - - interspecies interaction between organisms
MHCKMFAJ_00084 2.25e-259 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
MHCKMFAJ_00085 2.26e-93 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHCKMFAJ_00086 9.62e-189 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MHCKMFAJ_00087 2.94e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MHCKMFAJ_00088 1.37e-40 - - - S - - - YjbR
MHCKMFAJ_00089 3.35e-100 yycI - - S - - - YycH protein
MHCKMFAJ_00090 1.07e-125 yycH - - S - - - YycH protein
MHCKMFAJ_00091 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCKMFAJ_00092 6.95e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHCKMFAJ_00094 2.01e-185 comA - - V ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MHCKMFAJ_00095 2.6e-219 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MHCKMFAJ_00097 1e-135 yxeH - - S - - - hydrolase
MHCKMFAJ_00098 1.29e-285 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MHCKMFAJ_00099 1.77e-268 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_00100 2.33e-41 - - - K - - - Transcriptional regulator, MarR family
MHCKMFAJ_00101 3.71e-217 - - - S - - - Putative peptidoglycan binding domain
MHCKMFAJ_00102 4.48e-32 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MHCKMFAJ_00103 8.38e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MHCKMFAJ_00104 4.11e-175 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
MHCKMFAJ_00105 2.01e-224 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHCKMFAJ_00106 2.89e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHCKMFAJ_00107 7.89e-279 pepF - - E - - - Oligopeptidase F
MHCKMFAJ_00108 9.44e-121 yicL - - EG - - - EamA-like transporter family
MHCKMFAJ_00109 1.26e-89 - - - J - - - Acetyltransferase (GNAT) domain
MHCKMFAJ_00110 2.64e-212 - - - S - - - Putative threonine/serine exporter
MHCKMFAJ_00111 2.56e-140 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MHCKMFAJ_00112 2.97e-12 yobS - - K - - - Bacterial regulatory proteins, tetR family
MHCKMFAJ_00113 2.59e-192 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MHCKMFAJ_00114 7.35e-291 - - - L - - - COG3547 Transposase and inactivated derivatives
MHCKMFAJ_00115 9.5e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MHCKMFAJ_00116 7.22e-282 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MHCKMFAJ_00117 5.06e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHCKMFAJ_00118 5.01e-22 yneR - - - - - - -
MHCKMFAJ_00119 3.25e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHCKMFAJ_00121 3.32e-121 - - - M - - - Prophage endopeptidase tail
MHCKMFAJ_00122 0.0 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
MHCKMFAJ_00123 5.83e-113 - - - S - - - Phage tail protein
MHCKMFAJ_00124 8.11e-115 - - - L - - - Phage tail tape measure protein TP901
MHCKMFAJ_00131 2.35e-116 - - - S - - - Phage capsid family
MHCKMFAJ_00132 1.72e-91 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MHCKMFAJ_00133 2.41e-125 - - - S - - - Phage portal protein, HK97 family
MHCKMFAJ_00134 3.51e-269 - - - S - - - Terminase
MHCKMFAJ_00135 3.33e-43 - - - L - - - Phage terminase, small subunit
MHCKMFAJ_00136 2.29e-24 - - - L - - - HNH endonuclease
MHCKMFAJ_00141 8.63e-72 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MHCKMFAJ_00148 2.74e-81 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
MHCKMFAJ_00152 1.85e-86 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MHCKMFAJ_00154 1.18e-72 - - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_00155 1.07e-28 - - - S - - - HNH endonuclease
MHCKMFAJ_00156 3.1e-11 - - - - - - - -
MHCKMFAJ_00160 7.84e-46 - - - L - - - Psort location Cytoplasmic, score 8.96
MHCKMFAJ_00163 9.82e-190 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4 family
MHCKMFAJ_00164 1.85e-220 - - - L - - - DNA polymerase elongation subunit (Family B)
MHCKMFAJ_00165 1.76e-38 - - - S - - - Protein of unknown function (DUF669)
MHCKMFAJ_00166 3.13e-157 - - - L - - - AAA domain
MHCKMFAJ_00170 4.33e-140 - - - L - - - snf2 family
MHCKMFAJ_00175 1.82e-25 - - - S - - - Domain of unknown function (DUF771)
MHCKMFAJ_00178 7.74e-44 - - - K - - - Transcriptional regulator
MHCKMFAJ_00179 1.58e-19 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCKMFAJ_00180 3.85e-38 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCKMFAJ_00182 1.63e-18 - - - M - - - Host cell surface-exposed lipoprotein
MHCKMFAJ_00183 0.000447 - - - - - - - -
MHCKMFAJ_00186 1.22e-20 - - - - - - - -
MHCKMFAJ_00187 1.56e-142 int3 - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_00188 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHCKMFAJ_00189 5.21e-55 - - - S - - - repeat protein
MHCKMFAJ_00190 4.85e-128 pgm - - G - - - Phosphoglycerate mutase family
MHCKMFAJ_00191 3.01e-57 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MHCKMFAJ_00192 1.18e-116 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MHCKMFAJ_00193 7.75e-256 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
MHCKMFAJ_00195 4.25e-121 - - - - - - - -
MHCKMFAJ_00196 6.71e-14 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
MHCKMFAJ_00197 1e-68 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MHCKMFAJ_00198 3.05e-269 yhdG - - E ko:K03294 - ko00000 Amino Acid
MHCKMFAJ_00199 4.88e-315 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHCKMFAJ_00200 0.0 - - - L - - - Helicase C-terminal domain protein
MHCKMFAJ_00201 8.78e-102 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHCKMFAJ_00202 6.84e-232 yhdP - - S - - - Transporter associated domain
MHCKMFAJ_00203 1.95e-33 - - - - - - - -
MHCKMFAJ_00204 3.41e-94 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHCKMFAJ_00205 4.55e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MHCKMFAJ_00206 3.23e-125 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHCKMFAJ_00207 5.65e-92 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHCKMFAJ_00208 8.03e-199 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MHCKMFAJ_00209 1.97e-174 - - - V - - - MatE
MHCKMFAJ_00210 2.95e-58 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCKMFAJ_00211 7.83e-111 - - - S - - - Alpha beta hydrolase
MHCKMFAJ_00212 7.48e-122 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHCKMFAJ_00213 7.42e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHCKMFAJ_00214 4.34e-138 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MHCKMFAJ_00215 1.49e-129 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHCKMFAJ_00216 8.54e-45 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MHCKMFAJ_00217 3.29e-70 ccl - - S - - - QueT transporter
MHCKMFAJ_00219 3.29e-84 - - - S - - - Uncharacterised protein, DegV family COG1307
MHCKMFAJ_00220 8.32e-29 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHCKMFAJ_00221 2.19e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHCKMFAJ_00222 1.12e-45 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHCKMFAJ_00223 6.91e-109 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHCKMFAJ_00224 1.6e-154 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHCKMFAJ_00225 1.97e-64 - - - S - - - Threonine/Serine exporter, ThrE
MHCKMFAJ_00226 9.59e-104 - - - S - - - Putative threonine/serine exporter
MHCKMFAJ_00227 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MHCKMFAJ_00228 1.77e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
MHCKMFAJ_00229 1.01e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHCKMFAJ_00230 1.23e-27 - - - - - - - -
MHCKMFAJ_00231 6.46e-75 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
MHCKMFAJ_00232 1.65e-24 - - - - - - - -
MHCKMFAJ_00233 3.45e-81 - - - I - - - alpha/beta hydrolase fold
MHCKMFAJ_00234 2.61e-52 - - - S - - - branched-chain amino acid
MHCKMFAJ_00235 3.58e-132 - - - E - - - AzlC protein
MHCKMFAJ_00236 1.81e-24 - - - - - - - -
MHCKMFAJ_00237 7.25e-163 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MHCKMFAJ_00238 1.2e-155 yhgE - - V ko:K01421 - ko00000 domain protein
MHCKMFAJ_00239 0.000904 - - - S - - - zinc-ribbon domain
MHCKMFAJ_00241 8.68e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHCKMFAJ_00242 3.66e-216 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHCKMFAJ_00243 1.48e-148 ydbI - - K - - - AI-2E family transporter
MHCKMFAJ_00244 2.09e-76 - - - EG - - - EamA-like transporter family
MHCKMFAJ_00245 1.3e-97 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MHCKMFAJ_00246 4.86e-148 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MHCKMFAJ_00247 6.44e-34 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MHCKMFAJ_00248 5.56e-32 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 FMN reductase
MHCKMFAJ_00249 4.16e-118 - - - C - - - Luciferase-like monooxygenase
MHCKMFAJ_00250 3.18e-27 - - - C - - - Luciferase-like monooxygenase
MHCKMFAJ_00253 3.91e-54 - - - - - - - -
MHCKMFAJ_00254 6.3e-242 - - - S - - - COG0433 Predicted ATPase
MHCKMFAJ_00255 6.51e-33 - - - S - - - COG0433 Predicted ATPase
MHCKMFAJ_00257 3.74e-75 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
MHCKMFAJ_00260 4.96e-146 - - - S - - - Uncharacterised protein family (UPF0236)
MHCKMFAJ_00261 4.82e-147 - - - S - - - EDD domain protein, DegV family
MHCKMFAJ_00262 3.9e-91 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
MHCKMFAJ_00263 4.18e-18 - - - S - - - ASCH
MHCKMFAJ_00264 3.72e-236 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHCKMFAJ_00266 8.3e-146 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
MHCKMFAJ_00267 7.28e-27 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
MHCKMFAJ_00272 8.92e-82 - - - S - - - Domain of unknown function (DUF2479)
MHCKMFAJ_00275 0.0 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
MHCKMFAJ_00276 6.98e-183 - - - S - - - Phage tail protein
MHCKMFAJ_00277 0.0 - - - L - - - Phage tail tape measure protein TP901
MHCKMFAJ_00279 1.36e-74 - - - S - - - Phage tail assembly chaperone proteins, TAC
MHCKMFAJ_00280 5.19e-157 - - - S - - - Phage tail tube protein
MHCKMFAJ_00281 1.46e-84 - - - S - - - Protein of unknown function (DUF806)
MHCKMFAJ_00282 1.13e-84 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
MHCKMFAJ_00283 6.36e-78 - - - S - - - Phage head-tail joining protein
MHCKMFAJ_00284 1.08e-29 - - - S - - - Phage gp6-like head-tail connector protein
MHCKMFAJ_00285 1.51e-279 - - - S - - - Phage capsid family
MHCKMFAJ_00286 3.62e-155 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
MHCKMFAJ_00287 9.49e-262 - - - S - - - Phage portal protein
MHCKMFAJ_00289 0.0 - - - S - - - Phage Terminase
MHCKMFAJ_00290 3.95e-78 - - - L - - - Phage terminase, small subunit
MHCKMFAJ_00291 6.46e-114 - - - L - - - HNH nucleases
MHCKMFAJ_00295 1.6e-36 - - - S - - - Phage transcriptional regulator, ArpU family
MHCKMFAJ_00299 5.16e-66 - - - S - - - VRR_NUC
MHCKMFAJ_00300 7.38e-292 - - - S ko:K06919 - ko00000 Virulence-associated protein E
MHCKMFAJ_00301 1.1e-181 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
MHCKMFAJ_00302 9.92e-110 - - - - - - - -
MHCKMFAJ_00303 1.26e-148 - - - L - - - AAA domain
MHCKMFAJ_00304 1.18e-309 - - - L - - - Helicase C-terminal domain protein
MHCKMFAJ_00305 5.38e-101 - - - S - - - Siphovirus Gp157
MHCKMFAJ_00310 4.52e-153 - - - K - - - Transcriptional regulator
MHCKMFAJ_00311 1.29e-08 ansR - - K - - - transcriptional
MHCKMFAJ_00312 3.07e-25 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCKMFAJ_00314 3.27e-26 - - - - - - - -
MHCKMFAJ_00316 3.28e-146 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHCKMFAJ_00317 1.49e-193 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MHCKMFAJ_00318 1.93e-253 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MHCKMFAJ_00319 3.94e-249 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHCKMFAJ_00320 1.91e-187 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHCKMFAJ_00321 4.48e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHCKMFAJ_00322 1.54e-140 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHCKMFAJ_00324 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHCKMFAJ_00325 3.44e-66 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MHCKMFAJ_00326 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MHCKMFAJ_00327 1.36e-71 - - - EGP - - - Transmembrane secretion effector
MHCKMFAJ_00328 5.57e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHCKMFAJ_00329 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHCKMFAJ_00330 4.52e-27 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHCKMFAJ_00332 5.54e-139 dkgB - - S - - - reductase
MHCKMFAJ_00333 1.82e-33 - - - - - - - -
MHCKMFAJ_00334 1.6e-78 - - - L - - - Resolvase, N-terminal domain
MHCKMFAJ_00335 1.45e-120 - - - L - - - Probable transposase
MHCKMFAJ_00336 6.86e-100 - - - F - - - Phosphorylase superfamily
MHCKMFAJ_00337 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MHCKMFAJ_00338 3.47e-79 ytkL - - S - - - Beta-lactamase superfamily domain
MHCKMFAJ_00339 2.86e-123 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHCKMFAJ_00340 4.53e-156 yibE - - S - - - overlaps another CDS with the same product name
MHCKMFAJ_00341 3.33e-110 - - - S - - - overlaps another CDS with the same product name
MHCKMFAJ_00343 6.78e-63 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
MHCKMFAJ_00345 4.5e-89 - - - L - - - recombinase activity
MHCKMFAJ_00346 9.07e-91 - - - - - - - -
MHCKMFAJ_00347 8.64e-24 - - - - - - - -
MHCKMFAJ_00348 1.28e-88 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
MHCKMFAJ_00349 1.01e-110 - - - S - - - hydrolase
MHCKMFAJ_00350 2.43e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
MHCKMFAJ_00351 1e-109 - - - F - - - glutamine amidotransferase
MHCKMFAJ_00352 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
MHCKMFAJ_00353 8.08e-58 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHCKMFAJ_00354 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHCKMFAJ_00357 3.79e-254 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHCKMFAJ_00358 9.6e-241 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHCKMFAJ_00359 2.05e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MHCKMFAJ_00360 7.83e-79 - - - - - - - -
MHCKMFAJ_00361 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MHCKMFAJ_00362 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
MHCKMFAJ_00363 1.21e-302 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MHCKMFAJ_00364 1.1e-305 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHCKMFAJ_00365 1.08e-180 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHCKMFAJ_00366 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHCKMFAJ_00367 4.17e-129 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHCKMFAJ_00368 6.58e-289 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MHCKMFAJ_00369 1.84e-186 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHCKMFAJ_00370 6.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHCKMFAJ_00371 9.04e-263 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHCKMFAJ_00372 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MHCKMFAJ_00373 4.89e-38 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MHCKMFAJ_00374 2.27e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHCKMFAJ_00375 2.74e-145 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MHCKMFAJ_00376 2.19e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MHCKMFAJ_00377 3.56e-250 - - - E ko:K03294 - ko00000 amino acid
MHCKMFAJ_00378 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHCKMFAJ_00379 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MHCKMFAJ_00380 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHCKMFAJ_00381 7.62e-147 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHCKMFAJ_00382 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHCKMFAJ_00383 0.000113 - - - S - - - Tetratricopeptide repeat
MHCKMFAJ_00384 1.38e-273 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHCKMFAJ_00385 4.78e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHCKMFAJ_00386 2.59e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHCKMFAJ_00387 3.87e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHCKMFAJ_00388 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHCKMFAJ_00389 1.47e-30 ykzG - - S - - - Belongs to the UPF0356 family
MHCKMFAJ_00390 4.97e-33 - - - - - - - -
MHCKMFAJ_00391 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHCKMFAJ_00392 1.86e-22 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHCKMFAJ_00393 3.57e-33 yktA - - S - - - Belongs to the UPF0223 family
MHCKMFAJ_00394 1.22e-95 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MHCKMFAJ_00395 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MHCKMFAJ_00396 3.12e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHCKMFAJ_00397 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MHCKMFAJ_00398 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHCKMFAJ_00399 2.48e-125 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHCKMFAJ_00400 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHCKMFAJ_00401 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
MHCKMFAJ_00402 9.83e-91 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHCKMFAJ_00403 5.16e-53 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MHCKMFAJ_00406 4.92e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHCKMFAJ_00407 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHCKMFAJ_00408 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHCKMFAJ_00409 1.79e-255 oatA - - I - - - Acyltransferase
MHCKMFAJ_00410 2.38e-22 - - - - - - - -
MHCKMFAJ_00412 8.7e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHCKMFAJ_00413 1.37e-127 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
MHCKMFAJ_00414 8.24e-267 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHCKMFAJ_00415 3.03e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHCKMFAJ_00416 0.0 - - - S - - - membrane
MHCKMFAJ_00417 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHCKMFAJ_00418 6.91e-35 - - - S - - - Protein of unknown function (DUF3290)
MHCKMFAJ_00419 1.52e-96 yviA - - S - - - Protein of unknown function (DUF421)
MHCKMFAJ_00421 3.96e-156 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHCKMFAJ_00422 1.48e-252 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MHCKMFAJ_00423 4.84e-69 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MHCKMFAJ_00424 6.35e-97 uspA - - T - - - universal stress protein
MHCKMFAJ_00426 5.46e-246 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MHCKMFAJ_00427 1.46e-31 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MHCKMFAJ_00428 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHCKMFAJ_00429 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MHCKMFAJ_00430 6.54e-223 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHCKMFAJ_00431 1.02e-204 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHCKMFAJ_00432 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHCKMFAJ_00433 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHCKMFAJ_00434 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
MHCKMFAJ_00435 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHCKMFAJ_00436 3.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHCKMFAJ_00437 5.45e-268 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHCKMFAJ_00438 2.23e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHCKMFAJ_00439 1.11e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MHCKMFAJ_00440 3.91e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MHCKMFAJ_00441 1.81e-58 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MHCKMFAJ_00442 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHCKMFAJ_00443 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHCKMFAJ_00444 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHCKMFAJ_00445 7.33e-71 - - - - - - - -
MHCKMFAJ_00446 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHCKMFAJ_00447 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHCKMFAJ_00448 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHCKMFAJ_00449 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHCKMFAJ_00450 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MHCKMFAJ_00451 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHCKMFAJ_00452 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHCKMFAJ_00453 1.93e-92 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MHCKMFAJ_00454 1.88e-138 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHCKMFAJ_00455 3.45e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHCKMFAJ_00456 2.26e-263 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHCKMFAJ_00457 1.05e-312 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHCKMFAJ_00458 1.38e-195 yacL - - S - - - domain protein
MHCKMFAJ_00459 2.79e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHCKMFAJ_00460 3.38e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MHCKMFAJ_00461 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MHCKMFAJ_00462 5.18e-281 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MHCKMFAJ_00463 3.93e-45 - - - S - - - Enterocin A Immunity
MHCKMFAJ_00464 4.1e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHCKMFAJ_00465 2.13e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MHCKMFAJ_00466 2.66e-148 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHCKMFAJ_00468 9.77e-56 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MHCKMFAJ_00469 5.71e-317 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MHCKMFAJ_00470 2.65e-165 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHCKMFAJ_00471 3.1e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHCKMFAJ_00472 3.32e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHCKMFAJ_00473 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MHCKMFAJ_00474 1.5e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHCKMFAJ_00477 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MHCKMFAJ_00491 1.78e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MHCKMFAJ_00492 1.08e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MHCKMFAJ_00493 1.21e-83 coiA - - S ko:K06198 - ko00000 Competence protein
MHCKMFAJ_00494 2.89e-287 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MHCKMFAJ_00495 1.3e-53 yjbH - - Q - - - Thioredoxin
MHCKMFAJ_00496 4.34e-125 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHCKMFAJ_00497 5.19e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MHCKMFAJ_00498 1.35e-154 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MHCKMFAJ_00499 7.48e-147 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHCKMFAJ_00500 6.43e-149 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHCKMFAJ_00501 2.26e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MHCKMFAJ_00502 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MHCKMFAJ_00503 5.64e-100 - - - S - - - VIT family
MHCKMFAJ_00504 2.71e-107 - - - S - - - membrane
MHCKMFAJ_00505 1.13e-52 - - - K - - - Domain of unknown function (DUF1836)
MHCKMFAJ_00506 5.92e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MHCKMFAJ_00507 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHCKMFAJ_00508 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHCKMFAJ_00510 2.23e-10 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHCKMFAJ_00512 9.17e-219 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHCKMFAJ_00513 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MHCKMFAJ_00514 4.81e-54 - - - S - - - VanZ like family
MHCKMFAJ_00515 1.98e-153 yebC - - K - - - Transcriptional regulatory protein
MHCKMFAJ_00516 4.7e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHCKMFAJ_00517 1.29e-151 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MHCKMFAJ_00518 4.28e-25 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MHCKMFAJ_00519 1.4e-97 - - - V - - - N-6 DNA Methylase
MHCKMFAJ_00520 0.000468 - - - L - - - DNA restriction-modification system
MHCKMFAJ_00522 1.58e-153 - - - L - - - ISXO2-like transposase domain
MHCKMFAJ_00523 1.19e-71 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MHCKMFAJ_00524 8.75e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MHCKMFAJ_00525 7.13e-18 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MHCKMFAJ_00529 1.62e-122 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MHCKMFAJ_00530 2.02e-237 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHCKMFAJ_00531 4.57e-73 - - - S - - - Calcineurin-like phosphoesterase
MHCKMFAJ_00532 4.29e-77 yutD - - S - - - Protein of unknown function (DUF1027)
MHCKMFAJ_00533 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHCKMFAJ_00534 4.04e-39 - - - S - - - Protein of unknown function (DUF1461)
MHCKMFAJ_00535 1.06e-108 - - - L ko:K07496 - ko00000 Transposase, IS605 OrfB family
MHCKMFAJ_00536 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MHCKMFAJ_00538 1.38e-17 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MHCKMFAJ_00539 1.52e-60 - - - L ko:K07497 - ko00000 Integrase core domain
MHCKMFAJ_00540 7.6e-168 - - - EGP - - - Major Facilitator Superfamily
MHCKMFAJ_00541 2.84e-122 - - - EGP - - - Major Facilitator Superfamily
MHCKMFAJ_00542 8.05e-91 - - - K - - - Transcriptional regulator, LysR family
MHCKMFAJ_00543 2.12e-176 - - - G - - - Xylose isomerase-like TIM barrel
MHCKMFAJ_00544 1.73e-148 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHCKMFAJ_00545 2.95e-271 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MHCKMFAJ_00546 8.49e-175 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHCKMFAJ_00547 1.11e-87 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHCKMFAJ_00548 2.2e-181 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
MHCKMFAJ_00549 7.75e-14 - - - - - - - -
MHCKMFAJ_00550 2.15e-43 - - - - - - - -
MHCKMFAJ_00552 1.49e-19 - - - S - - - YjcQ protein
MHCKMFAJ_00555 2.29e-128 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MHCKMFAJ_00556 1.85e-89 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHCKMFAJ_00557 1.23e-99 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MHCKMFAJ_00558 4.33e-73 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCKMFAJ_00559 2.75e-67 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MHCKMFAJ_00560 2.97e-101 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHCKMFAJ_00561 6.66e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHCKMFAJ_00562 3.52e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MHCKMFAJ_00563 3.37e-24 - - - - - - - -
MHCKMFAJ_00564 5.32e-18 - - - - - - - -
MHCKMFAJ_00565 3.73e-142 rssA - - S - - - Phospholipase, patatin family
MHCKMFAJ_00566 5.49e-175 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHCKMFAJ_00567 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MHCKMFAJ_00568 2.34e-64 - - - S - - - VIT family
MHCKMFAJ_00569 9.19e-304 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MHCKMFAJ_00570 1.9e-52 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MHCKMFAJ_00571 1.09e-181 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHCKMFAJ_00572 3.71e-180 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MHCKMFAJ_00573 1.5e-147 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MHCKMFAJ_00574 2.72e-282 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHCKMFAJ_00575 1.33e-179 - - - P - - - Voltage gated chloride channel
MHCKMFAJ_00576 3.83e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCKMFAJ_00577 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MHCKMFAJ_00578 7.3e-59 - - - V - - - Type I restriction modification DNA specificity domain
MHCKMFAJ_00579 5.97e-312 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MHCKMFAJ_00580 5.36e-69 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MHCKMFAJ_00582 1.1e-172 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHCKMFAJ_00583 9.61e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MHCKMFAJ_00584 2.33e-82 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
MHCKMFAJ_00585 2.21e-47 pts38A 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHCKMFAJ_00586 5.41e-173 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MHCKMFAJ_00587 1.93e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MHCKMFAJ_00588 7.01e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MHCKMFAJ_00589 2.84e-95 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHCKMFAJ_00590 1.37e-140 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MHCKMFAJ_00591 6.65e-54 - - - L - - - Phage tail tape measure protein TP901
MHCKMFAJ_00593 1.59e-11 - - - - - - - -
MHCKMFAJ_00598 1.7e-31 - - - S - - - Phage minor capsid protein 2
MHCKMFAJ_00599 6.18e-125 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MHCKMFAJ_00600 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MHCKMFAJ_00602 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MHCKMFAJ_00603 7.2e-89 - - - L - - - Phage integrase, N-terminal SAM-like domain
MHCKMFAJ_00604 8.13e-13 blpT - - - - - - -
MHCKMFAJ_00605 1.94e-18 - - - - - - - -
MHCKMFAJ_00607 1.23e-37 - - - S - - - Phage gp6-like head-tail connector protein
MHCKMFAJ_00608 5.27e-123 - - - - - - - -
MHCKMFAJ_00609 1.89e-16 - - - S - - - Domain of unknown function (DUF4355)
MHCKMFAJ_00612 3.95e-32 - - - S - - - Phage Mu protein F like protein
MHCKMFAJ_00614 1.15e-236 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHCKMFAJ_00615 9.31e-103 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
MHCKMFAJ_00616 5.17e-104 - - - G - - - Peptidase_C39 like family
MHCKMFAJ_00618 1.56e-161 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MHCKMFAJ_00619 9.94e-58 - - - S - - - zinc-ribbon domain
MHCKMFAJ_00620 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MHCKMFAJ_00621 7.97e-206 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHCKMFAJ_00622 2.13e-118 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHCKMFAJ_00623 1.23e-85 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MHCKMFAJ_00624 3.92e-194 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
MHCKMFAJ_00625 6.39e-69 - - - T ko:K16923 - ko00000,ko00002,ko02000 phosphorelay sensor kinase activity
MHCKMFAJ_00626 5.48e-188 iunH3 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Inosine-uridine preferring nucleoside hydrolase
MHCKMFAJ_00627 5.46e-58 cps3I - - G - - - Acyltransferase family
MHCKMFAJ_00628 4.55e-20 - - - - - - - -
MHCKMFAJ_00629 4.5e-149 - - - S - - - Bacterial membrane protein YfhO
MHCKMFAJ_00630 4.36e-193 XK27_08315 - - M - - - Sulfatase
MHCKMFAJ_00631 7.59e-88 - - - M - - - Domain of unknown function (DUF4422)
MHCKMFAJ_00632 4.77e-72 - - - - - - - -
MHCKMFAJ_00633 9.64e-109 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
MHCKMFAJ_00634 2.02e-77 - - - S - - - Psort location CytoplasmicMembrane, score
MHCKMFAJ_00635 4.49e-94 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MHCKMFAJ_00636 1.47e-223 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MHCKMFAJ_00637 2.44e-160 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHCKMFAJ_00638 7.25e-214 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MHCKMFAJ_00639 1.63e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHCKMFAJ_00640 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHCKMFAJ_00641 1.85e-161 - - - - - - - -
MHCKMFAJ_00642 7.19e-189 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MHCKMFAJ_00643 5.94e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
MHCKMFAJ_00644 5.39e-40 - - - K - - - Bacterial regulatory proteins, tetR family
MHCKMFAJ_00645 3.03e-86 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHCKMFAJ_00646 1.19e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHCKMFAJ_00647 1.6e-128 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHCKMFAJ_00648 2.31e-216 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHCKMFAJ_00649 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHCKMFAJ_00650 0.0 - - - L - - - DNA helicase
MHCKMFAJ_00652 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MHCKMFAJ_00653 2.31e-94 lemA - - S ko:K03744 - ko00000 LemA family
MHCKMFAJ_00654 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
MHCKMFAJ_00655 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
MHCKMFAJ_00656 1.29e-11 - - - - - - - -
MHCKMFAJ_00657 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHCKMFAJ_00658 7.59e-279 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_00659 6.28e-44 - - - K - - - Bacterial regulatory proteins, tetR family
MHCKMFAJ_00660 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_00661 1.1e-277 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHCKMFAJ_00662 2.38e-189 - - - G - - - Transporter, major facilitator family protein
MHCKMFAJ_00663 4.13e-48 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MHCKMFAJ_00664 1.29e-200 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MHCKMFAJ_00665 1.06e-76 - - - L ko:K07491 - ko00000 Transposase IS200 like
MHCKMFAJ_00666 1.75e-161 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
MHCKMFAJ_00667 7.24e-121 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
MHCKMFAJ_00668 5.94e-16 - - - L ko:K07498 - ko00000 Transposase
MHCKMFAJ_00669 8.61e-67 - - - C - - - Oxidoreductase NAD-binding domain
MHCKMFAJ_00670 3.22e-140 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MHCKMFAJ_00671 1.23e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
MHCKMFAJ_00672 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MHCKMFAJ_00673 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHCKMFAJ_00674 2.12e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
MHCKMFAJ_00675 3.09e-59 ykuL - - S - - - CBS domain
MHCKMFAJ_00676 2.43e-92 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHCKMFAJ_00677 4.06e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHCKMFAJ_00678 2.28e-115 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MHCKMFAJ_00681 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHCKMFAJ_00682 2.92e-28 yheA - - S - - - Belongs to the UPF0342 family
MHCKMFAJ_00683 1.32e-162 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHCKMFAJ_00684 1.35e-96 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
MHCKMFAJ_00685 1.22e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHCKMFAJ_00687 3.15e-69 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MHCKMFAJ_00688 8.15e-122 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_00689 8.93e-87 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHCKMFAJ_00690 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
MHCKMFAJ_00691 8.2e-131 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHCKMFAJ_00692 5.96e-59 ytpP - - CO - - - Thioredoxin
MHCKMFAJ_00693 2.58e-97 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHCKMFAJ_00694 1.07e-10 - - - - - - - -
MHCKMFAJ_00697 5.63e-20 - - - L - - - DnaD domain protein
MHCKMFAJ_00704 1.46e-59 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
MHCKMFAJ_00706 2.52e-20 ansR - - K - - - Transcriptional regulator
MHCKMFAJ_00707 3.08e-152 - - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_00708 6e-299 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHCKMFAJ_00709 7.15e-282 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MHCKMFAJ_00710 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
MHCKMFAJ_00711 1.2e-87 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MHCKMFAJ_00717 1.05e-82 - - - H - - - Methyltransferase domain
MHCKMFAJ_00718 3.26e-93 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MHCKMFAJ_00719 3.92e-52 - - - M - - - Acetyltransferase (GNAT) family
MHCKMFAJ_00721 4.47e-29 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
MHCKMFAJ_00722 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
MHCKMFAJ_00724 0.0 - - - LV - - - site-specific DNA-methyltransferase (adenine-specific) activity
MHCKMFAJ_00725 3.33e-106 - - - L - - - Restriction endonuclease
MHCKMFAJ_00726 1.99e-80 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MHCKMFAJ_00727 4.83e-41 - - - S - - - CHY zinc finger
MHCKMFAJ_00728 2.54e-53 ywnA - - K - - - Transcriptional regulator
MHCKMFAJ_00729 4.86e-106 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
MHCKMFAJ_00731 6.74e-52 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHCKMFAJ_00732 4.57e-223 rsmF - - J - - - NOL1 NOP2 sun family protein
MHCKMFAJ_00733 4.68e-81 - - - - - - - -
MHCKMFAJ_00734 7.47e-104 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
MHCKMFAJ_00735 5.02e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MHCKMFAJ_00736 1.12e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MHCKMFAJ_00737 8.93e-237 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHCKMFAJ_00738 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MHCKMFAJ_00739 7.9e-267 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHCKMFAJ_00741 2.95e-80 - - - K - - - helix_turn_helix, arabinose operon control protein
MHCKMFAJ_00742 7.03e-57 - - - S - - - Membrane
MHCKMFAJ_00743 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MHCKMFAJ_00744 1.99e-107 - - - L - - - Helicase C-terminal domain protein
MHCKMFAJ_00745 6.53e-49 - - - L - - - Helicase C-terminal domain protein
MHCKMFAJ_00747 2.37e-181 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
MHCKMFAJ_00748 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MHCKMFAJ_00749 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHCKMFAJ_00750 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MHCKMFAJ_00751 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
MHCKMFAJ_00752 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHCKMFAJ_00753 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHCKMFAJ_00754 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
MHCKMFAJ_00755 1.65e-201 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHCKMFAJ_00756 1.26e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHCKMFAJ_00758 1.21e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MHCKMFAJ_00759 4.92e-165 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHCKMFAJ_00760 1.34e-220 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MHCKMFAJ_00761 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MHCKMFAJ_00762 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MHCKMFAJ_00763 3.65e-255 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MHCKMFAJ_00764 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MHCKMFAJ_00765 1.72e-174 - - - EG - - - EamA-like transporter family
MHCKMFAJ_00766 4.98e-62 - - - L - - - DNA alkylation repair enzyme
MHCKMFAJ_00767 4e-11 alkD - - L - - - DNA alkylation repair enzyme
MHCKMFAJ_00768 1.76e-232 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MHCKMFAJ_00769 5.44e-130 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHCKMFAJ_00770 6.85e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MHCKMFAJ_00771 4.13e-185 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
MHCKMFAJ_00773 7.6e-08 - - - S - - - peptidoglycan binding
MHCKMFAJ_00777 3.66e-101 - - - L ko:K07497 - ko00000 hmm pf00665
MHCKMFAJ_00779 1.04e-48 - - - L - - - Helix-turn-helix domain
MHCKMFAJ_00780 3.86e-188 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MHCKMFAJ_00781 2.54e-38 - - - S - - - Glycosyltransferase like family 2
MHCKMFAJ_00782 9.26e-134 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MHCKMFAJ_00783 2.57e-77 nss - - M - - - transferase activity, transferring glycosyl groups
MHCKMFAJ_00784 2.72e-08 - - - M - - - Psort location Cytoplasmic, score 8.87
MHCKMFAJ_00785 9.45e-27 arbY - - M - - - family 8
MHCKMFAJ_00787 3.86e-66 - - - M - - - transferase activity, transferring glycosyl groups
MHCKMFAJ_00788 2.77e-41 - - - M - - - Glycosyl transferase, family 8
MHCKMFAJ_00789 1.54e-82 nss - - M - - - transferase activity, transferring glycosyl groups
MHCKMFAJ_00790 2.15e-36 cpsJ - - M - - - Glycosyltransferase group 2 family protein
MHCKMFAJ_00791 3.1e-07 - - - M - - - Glycosyltransferase, group 2 family protein
MHCKMFAJ_00792 1.35e-19 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
MHCKMFAJ_00793 3.66e-184 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MHCKMFAJ_00794 3.31e-189 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MHCKMFAJ_00795 2.07e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHCKMFAJ_00796 3.54e-140 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MHCKMFAJ_00797 1.08e-251 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MHCKMFAJ_00798 2.65e-35 - - - - - - - -
MHCKMFAJ_00799 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
MHCKMFAJ_00800 2.03e-77 - - - T - - - Universal stress protein family
MHCKMFAJ_00801 2.06e-68 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MHCKMFAJ_00802 4.57e-32 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MHCKMFAJ_00803 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHCKMFAJ_00804 1.61e-91 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MHCKMFAJ_00805 1.4e-104 ylmH - - S - - - S4 domain protein
MHCKMFAJ_00806 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
MHCKMFAJ_00807 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHCKMFAJ_00808 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHCKMFAJ_00809 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHCKMFAJ_00810 6.44e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHCKMFAJ_00811 1.05e-195 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHCKMFAJ_00812 2.56e-234 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHCKMFAJ_00813 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHCKMFAJ_00814 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHCKMFAJ_00815 1.05e-13 ftsL - - D - - - Essential cell division protein
MHCKMFAJ_00816 6.07e-179 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHCKMFAJ_00817 2.65e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MHCKMFAJ_00819 1.55e-195 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
MHCKMFAJ_00820 6.26e-123 ybcH - - D ko:K06889 - ko00000 Alpha beta
MHCKMFAJ_00821 1.31e-137 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MHCKMFAJ_00822 9.96e-116 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_00823 1.67e-119 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_00824 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MHCKMFAJ_00825 4.14e-97 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHCKMFAJ_00826 3.99e-72 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MHCKMFAJ_00827 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MHCKMFAJ_00828 3.89e-206 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MHCKMFAJ_00829 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
MHCKMFAJ_00830 9.85e-161 - - - Q - - - Thiopurine S-methyltransferase (TPMT)
MHCKMFAJ_00831 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MHCKMFAJ_00832 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MHCKMFAJ_00833 1.56e-257 ynbB - - P - - - aluminum resistance
MHCKMFAJ_00834 4.97e-140 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHCKMFAJ_00835 3.58e-23 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MHCKMFAJ_00836 1.69e-59 yqhL - - P - - - Rhodanese-like protein
MHCKMFAJ_00837 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MHCKMFAJ_00838 1.74e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MHCKMFAJ_00839 9.08e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MHCKMFAJ_00840 2.55e-49 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHCKMFAJ_00841 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHCKMFAJ_00843 8.17e-88 yciQ - - P - - - membrane protein (DUF2207)
MHCKMFAJ_00844 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
MHCKMFAJ_00845 1.38e-119 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MHCKMFAJ_00846 6.62e-35 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MHCKMFAJ_00847 7.41e-41 ynzC - - S - - - UPF0291 protein
MHCKMFAJ_00848 1.29e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHCKMFAJ_00849 1.49e-235 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MHCKMFAJ_00850 5.91e-65 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHCKMFAJ_00851 6.31e-154 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MHCKMFAJ_00852 2.17e-103 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHCKMFAJ_00853 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHCKMFAJ_00854 2.46e-183 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHCKMFAJ_00855 3.32e-133 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHCKMFAJ_00856 7.18e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHCKMFAJ_00857 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MHCKMFAJ_00858 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHCKMFAJ_00859 1.45e-48 - - - S - - - Protein conserved in bacteria
MHCKMFAJ_00860 3.98e-148 - - - - - - - -
MHCKMFAJ_00861 4.27e-143 - - - - - - - -
MHCKMFAJ_00862 1.01e-171 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MHCKMFAJ_00863 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MHCKMFAJ_00864 1.19e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHCKMFAJ_00865 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHCKMFAJ_00866 5.34e-164 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MHCKMFAJ_00867 1.17e-23 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MHCKMFAJ_00868 4.93e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHCKMFAJ_00869 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHCKMFAJ_00870 3.2e-121 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MHCKMFAJ_00871 2.62e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHCKMFAJ_00872 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHCKMFAJ_00873 4.21e-136 ymfF - - S - - - Peptidase M16 inactive domain protein
MHCKMFAJ_00874 1.82e-186 ymfH - - S - - - Peptidase M16
MHCKMFAJ_00875 5.2e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHCKMFAJ_00876 7.25e-85 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MHCKMFAJ_00877 2.09e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHCKMFAJ_00878 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHCKMFAJ_00879 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MHCKMFAJ_00880 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHCKMFAJ_00881 2e-287 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHCKMFAJ_00882 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHCKMFAJ_00883 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHCKMFAJ_00884 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHCKMFAJ_00885 5.96e-263 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHCKMFAJ_00886 1.06e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
MHCKMFAJ_00887 1e-19 yvgN - - C - - - Aldo keto reductase
MHCKMFAJ_00888 3.84e-50 - - - S - - - Haem-degrading
MHCKMFAJ_00889 1.65e-210 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MHCKMFAJ_00890 2.2e-204 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHCKMFAJ_00891 3.53e-149 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
MHCKMFAJ_00892 1.51e-190 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MHCKMFAJ_00893 1.54e-216 iolG 1.1.1.18, 1.1.1.369 - C ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MHCKMFAJ_00894 2.84e-225 - - - EGP - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHCKMFAJ_00895 1.49e-18 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MHCKMFAJ_00896 1.46e-110 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MHCKMFAJ_00897 3.58e-236 - - - E - - - SAF
MHCKMFAJ_00898 2.69e-24 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHCKMFAJ_00899 2.31e-94 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MHCKMFAJ_00900 5.7e-138 pts38BC 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MHCKMFAJ_00901 4.32e-11 - - - K ko:K02466 - ko00000 Glucitol operon activator protein (GutM)
MHCKMFAJ_00902 0.000392 sorC2 - - K - - - transcriptional regulator
MHCKMFAJ_00903 8.13e-42 deoR_2 - - K - - - Putative sugar-binding domain
MHCKMFAJ_00904 2.92e-115 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHCKMFAJ_00905 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHCKMFAJ_00906 7.03e-72 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MHCKMFAJ_00907 9.79e-142 garR 1.1.1.60 - I ko:K00042 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MHCKMFAJ_00908 1.28e-189 - - - S - - - Protein conserved in bacteria
MHCKMFAJ_00909 1.66e-174 - - - EG ko:K06155 - ko00000,ko02000 Gluconate
MHCKMFAJ_00911 2.03e-75 - - - S - - - COG NOG19168 non supervised orthologous group
MHCKMFAJ_00912 1.44e-38 - - - S ko:K07334 - ko00000,ko02048 RelE-like toxin of type II toxin-antitoxin system HigB
MHCKMFAJ_00913 1.11e-37 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCKMFAJ_00914 7.41e-07 - - - - - - - -
MHCKMFAJ_00915 1.43e-240 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
MHCKMFAJ_00917 2.42e-113 - - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_00918 1.11e-35 hxlR - - K - - - Transcriptional regulator, HxlR family
MHCKMFAJ_00919 1.11e-217 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHCKMFAJ_00920 8.5e-132 gntR - - K - - - UbiC transcription regulator-associated domain protein
MHCKMFAJ_00921 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MHCKMFAJ_00922 4.18e-107 pncA - - Q - - - isochorismatase
MHCKMFAJ_00923 1.97e-82 pgm1 - - G - - - phosphoglycerate mutase
MHCKMFAJ_00924 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCKMFAJ_00925 2.39e-108 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MHCKMFAJ_00926 4.28e-315 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHCKMFAJ_00927 1.55e-212 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MHCKMFAJ_00930 3.52e-225 XK27_08315 - - M - - - Sulfatase
MHCKMFAJ_00931 2.44e-68 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
MHCKMFAJ_00932 8.2e-235 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MHCKMFAJ_00933 7.01e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MHCKMFAJ_00934 5.49e-150 - - - M - - - Core-2/I-Branching enzyme
MHCKMFAJ_00935 2.93e-116 epsE2 - - M - - - Bacterial sugar transferase
MHCKMFAJ_00936 1.29e-161 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHCKMFAJ_00937 5.99e-142 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MHCKMFAJ_00938 1.14e-117 ywqD - - D - - - Capsular exopolysaccharide family
MHCKMFAJ_00939 5.82e-93 epsB - - M - - - biosynthesis protein
MHCKMFAJ_00941 7.76e-140 cps2J - - S - - - Polysaccharide biosynthesis protein
MHCKMFAJ_00942 1.61e-82 - - - S ko:K16710 - ko00000 Polysaccharide pyruvyl transferase
MHCKMFAJ_00944 3.61e-30 - - - M - - - family 8
MHCKMFAJ_00945 1.53e-113 - - - - - - - -
MHCKMFAJ_00946 2.23e-49 - - - M - - - group 2 family protein
MHCKMFAJ_00947 1.35e-121 - - - M - - - Glycosyl transferase family 8
MHCKMFAJ_00948 3.67e-110 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHCKMFAJ_00950 2.88e-146 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
MHCKMFAJ_00951 1.2e-165 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHCKMFAJ_00952 7.18e-236 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHCKMFAJ_00953 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MHCKMFAJ_00954 2.69e-179 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHCKMFAJ_00955 1.03e-75 - - - S - - - Glycosyltransferase like family 2
MHCKMFAJ_00956 1.41e-148 cps3J - - M - - - Domain of unknown function (DUF4422)
MHCKMFAJ_00957 4.74e-45 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHCKMFAJ_00958 2.62e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MHCKMFAJ_00959 2.95e-81 - - - S - - - Haloacid dehalogenase-like hydrolase
MHCKMFAJ_00960 7.52e-193 - - - EGP - - - Major Facilitator
MHCKMFAJ_00962 1.09e-87 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHCKMFAJ_00963 9.23e-36 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
MHCKMFAJ_00964 5.11e-112 - - - S - - - NADPH-dependent FMN reductase
MHCKMFAJ_00965 2.11e-131 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHCKMFAJ_00966 1.98e-71 - - - S - - - ECF transporter, substrate-specific component
MHCKMFAJ_00967 2.1e-139 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MHCKMFAJ_00968 1.6e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHCKMFAJ_00969 1.27e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHCKMFAJ_00970 2.75e-46 - - - - - - - -
MHCKMFAJ_00971 8.88e-14 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MHCKMFAJ_00972 1.82e-67 - - - I - - - Alpha/beta hydrolase family
MHCKMFAJ_00973 8.51e-115 - - - S - - - Bacterial membrane protein, YfhO
MHCKMFAJ_00974 3.13e-73 - - - S - - - Protein of unknown function (DUF1129)
MHCKMFAJ_00975 2.94e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHCKMFAJ_00976 2.56e-32 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MHCKMFAJ_00977 4.14e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHCKMFAJ_00978 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MHCKMFAJ_00979 8.74e-104 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHCKMFAJ_00980 3.62e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MHCKMFAJ_00981 3.88e-160 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHCKMFAJ_00982 1.97e-92 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MHCKMFAJ_00983 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHCKMFAJ_00984 2.24e-76 - - - L - - - Probable transposase
MHCKMFAJ_00985 5.6e-17 - - - - - - - -
MHCKMFAJ_00986 1.24e-183 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
MHCKMFAJ_00987 6.01e-55 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
MHCKMFAJ_00988 8.83e-149 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MHCKMFAJ_00989 1.52e-97 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHCKMFAJ_00990 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHCKMFAJ_00991 7.24e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHCKMFAJ_00992 8.95e-73 yjcF - - J - - - HAD-hyrolase-like
MHCKMFAJ_00993 4.45e-55 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHCKMFAJ_00994 3.96e-163 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHCKMFAJ_00995 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHCKMFAJ_00996 1.07e-256 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MHCKMFAJ_00997 1.05e-140 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHCKMFAJ_00998 7.36e-238 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MHCKMFAJ_00999 1.5e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHCKMFAJ_01000 7.08e-113 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHCKMFAJ_01001 1.34e-172 - - - K - - - Transcriptional regulator
MHCKMFAJ_01002 7.65e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MHCKMFAJ_01003 1.16e-147 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHCKMFAJ_01004 4.96e-219 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHCKMFAJ_01005 2.01e-110 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MHCKMFAJ_01007 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHCKMFAJ_01008 3.81e-218 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MHCKMFAJ_01009 6.27e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MHCKMFAJ_01010 4.15e-34 - - - S - - - Family of unknown function (DUF5322)
MHCKMFAJ_01011 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MHCKMFAJ_01012 6.15e-51 - - - - - - - -
MHCKMFAJ_01013 2.83e-196 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCKMFAJ_01014 2.46e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHCKMFAJ_01015 7.43e-217 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCKMFAJ_01016 2.8e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHCKMFAJ_01017 3.07e-254 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHCKMFAJ_01018 2.16e-277 yifK - - E ko:K03293 - ko00000 Amino acid permease
MHCKMFAJ_01019 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHCKMFAJ_01020 2.49e-71 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHCKMFAJ_01021 1.54e-81 pgm3 - - G - - - phosphoglycerate mutase
MHCKMFAJ_01022 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MHCKMFAJ_01023 1.02e-26 - - - S - - - Cupredoxin-like domain
MHCKMFAJ_01024 5.2e-57 - - - S - - - Cupredoxin-like domain
MHCKMFAJ_01025 2.9e-189 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MHCKMFAJ_01026 1.12e-28 - - - K - - - transcriptional regulator
MHCKMFAJ_01027 6.18e-97 - - - S - - - intracellular protease amidase
MHCKMFAJ_01028 1.16e-171 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MHCKMFAJ_01029 4.75e-102 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MHCKMFAJ_01030 1.69e-177 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHCKMFAJ_01031 2.4e-254 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MHCKMFAJ_01032 7.24e-149 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MHCKMFAJ_01033 2.46e-122 - - - J - - - Aminoglycoside-2''-adenylyltransferase
MHCKMFAJ_01034 5.22e-255 - - - L - - - transposition, DNA-mediated
MHCKMFAJ_01035 5.76e-221 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MHCKMFAJ_01037 6.13e-47 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHCKMFAJ_01038 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
MHCKMFAJ_01039 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MHCKMFAJ_01040 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHCKMFAJ_01041 5.76e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHCKMFAJ_01042 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MHCKMFAJ_01043 2.52e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MHCKMFAJ_01044 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHCKMFAJ_01045 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHCKMFAJ_01046 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MHCKMFAJ_01047 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MHCKMFAJ_01048 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MHCKMFAJ_01049 4.38e-35 ylxQ - - J - - - ribosomal protein
MHCKMFAJ_01050 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHCKMFAJ_01051 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHCKMFAJ_01052 1.16e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHCKMFAJ_01053 7.4e-120 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MHCKMFAJ_01054 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHCKMFAJ_01055 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHCKMFAJ_01056 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MHCKMFAJ_01057 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHCKMFAJ_01058 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHCKMFAJ_01059 1.89e-291 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHCKMFAJ_01060 1.48e-139 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
MHCKMFAJ_01061 1.73e-129 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MHCKMFAJ_01062 3.3e-160 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHCKMFAJ_01063 1.45e-274 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MHCKMFAJ_01064 7.97e-85 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHCKMFAJ_01065 1.35e-59 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHCKMFAJ_01066 1e-247 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHCKMFAJ_01067 2.21e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MHCKMFAJ_01068 3.45e-130 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MHCKMFAJ_01069 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHCKMFAJ_01070 4.26e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHCKMFAJ_01071 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
MHCKMFAJ_01072 9.26e-87 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHCKMFAJ_01073 5.97e-49 - - - - - - - -
MHCKMFAJ_01075 3.18e-224 - - - S - - - Protein of unknown function DUF262
MHCKMFAJ_01076 2.17e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MHCKMFAJ_01077 8.94e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHCKMFAJ_01078 1.04e-79 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHCKMFAJ_01079 9.88e-244 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHCKMFAJ_01080 6.58e-245 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHCKMFAJ_01081 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MHCKMFAJ_01082 1.05e-225 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHCKMFAJ_01084 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHCKMFAJ_01085 6.67e-70 - - - S - - - Protein of unknown function (DUF1211)
MHCKMFAJ_01086 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHCKMFAJ_01087 2.26e-81 - - - D - - - peptidase
MHCKMFAJ_01088 1.33e-147 - - - S - - - Glycosyl transferase family 2
MHCKMFAJ_01089 2.13e-140 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MHCKMFAJ_01090 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHCKMFAJ_01091 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHCKMFAJ_01092 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MHCKMFAJ_01093 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHCKMFAJ_01094 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHCKMFAJ_01095 5.91e-194 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHCKMFAJ_01096 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
MHCKMFAJ_01097 1.27e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHCKMFAJ_01098 4.47e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHCKMFAJ_01099 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MHCKMFAJ_01100 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHCKMFAJ_01101 3.1e-137 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHCKMFAJ_01102 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
MHCKMFAJ_01103 1.17e-152 - - - S - - - Conserved hypothetical protein 698
MHCKMFAJ_01104 1.77e-67 - - - K - - - LysR substrate binding domain
MHCKMFAJ_01106 9.7e-84 icaB - - G - - - Polysaccharide deacetylase
MHCKMFAJ_01107 3.46e-39 - - - S - - - Belongs to the HesB IscA family
MHCKMFAJ_01111 3.52e-42 - - - S - - - Phage transcriptional regulator, ArpU family
MHCKMFAJ_01112 2.48e-114 - - - L - - - Psort location Cytoplasmic, score
MHCKMFAJ_01113 8.25e-30 - 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 S-adenosylmethionine decarboxylase
MHCKMFAJ_01114 2.93e-54 - - - L - - - transposase activity
MHCKMFAJ_01115 9.36e-166 - - - S - - - Terminase-like family
MHCKMFAJ_01116 1.38e-199 - - - S - - - Phage portal protein, SPP1 Gp6-like
MHCKMFAJ_01119 3.2e-131 gpG - - - - - - -
MHCKMFAJ_01120 1.09e-46 - - - S - - - Phage gp6-like head-tail connector protein
MHCKMFAJ_01122 2.4e-42 - - - - - - - -
MHCKMFAJ_01123 5.15e-21 - - - - - - - -
MHCKMFAJ_01124 7.18e-59 - - - - - - - -
MHCKMFAJ_01127 3.29e-92 - - - D - - - domain protein
MHCKMFAJ_01128 3.63e-96 - - - S - - - Phage tail protein
MHCKMFAJ_01129 4.05e-94 - - - M - - - Prophage endopeptidase tail
MHCKMFAJ_01130 4.2e-122 - - - M - - - Prophage endopeptidase tail
MHCKMFAJ_01132 2.8e-30 - - - S - - - Calcineurin-like phosphoesterase
MHCKMFAJ_01134 3.52e-181 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHCKMFAJ_01136 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MHCKMFAJ_01137 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHCKMFAJ_01138 1.97e-204 camS - - S - - - sex pheromone
MHCKMFAJ_01139 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHCKMFAJ_01140 7.24e-295 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHCKMFAJ_01141 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHCKMFAJ_01142 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MHCKMFAJ_01143 5.57e-271 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHCKMFAJ_01145 0.0 mcrB - - V ko:K07452 - ko00000,ko01000,ko02048 ATPase family associated with various cellular activities (AAA)
MHCKMFAJ_01146 4.24e-213 mcrC - - V ko:K19147 - ko00000,ko02048 Psort location Cytoplasmic, score
MHCKMFAJ_01148 1.62e-13 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
MHCKMFAJ_01149 3.51e-38 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHCKMFAJ_01150 5.37e-84 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHCKMFAJ_01151 4.64e-105 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHCKMFAJ_01152 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
MHCKMFAJ_01153 9.92e-121 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHCKMFAJ_01154 6.03e-105 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MHCKMFAJ_01155 2.69e-176 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MHCKMFAJ_01156 8.6e-87 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MHCKMFAJ_01157 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHCKMFAJ_01158 2.92e-205 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHCKMFAJ_01159 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MHCKMFAJ_01160 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHCKMFAJ_01161 2.85e-41 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHCKMFAJ_01162 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHCKMFAJ_01163 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHCKMFAJ_01164 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
MHCKMFAJ_01165 0.0 ydaO - - E - - - amino acid
MHCKMFAJ_01166 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MHCKMFAJ_01167 3.04e-159 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MHCKMFAJ_01168 3.7e-67 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MHCKMFAJ_01169 1.42e-108 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MHCKMFAJ_01170 2.33e-29 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
MHCKMFAJ_01182 8.04e-55 - - - S - - - PD-(D/E)XK nuclease family transposase
MHCKMFAJ_01184 1.44e-67 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
MHCKMFAJ_01185 1.22e-33 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHCKMFAJ_01188 3.95e-54 - - - M - - - hmm tigr01076
MHCKMFAJ_01189 1.25e-104 - - - M - - - Gram-positive pilin backbone subunit 2, Cna-B-like domain
MHCKMFAJ_01193 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHCKMFAJ_01194 4.54e-87 ybbR - - S - - - YbbR-like protein
MHCKMFAJ_01195 1.95e-162 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHCKMFAJ_01196 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
MHCKMFAJ_01197 4.26e-146 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MHCKMFAJ_01198 3.34e-90 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHCKMFAJ_01199 1e-72 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MHCKMFAJ_01200 4.05e-180 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MHCKMFAJ_01201 2.16e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHCKMFAJ_01202 1.68e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHCKMFAJ_01203 1.37e-53 - - - - - - - -
MHCKMFAJ_01204 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHCKMFAJ_01205 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHCKMFAJ_01206 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MHCKMFAJ_01207 4.45e-224 eriC - - P ko:K03281 - ko00000 chloride
MHCKMFAJ_01208 5.39e-189 - - - E - - - Major Facilitator Superfamily
MHCKMFAJ_01209 9.3e-211 yclK - - T - - - Histidine kinase
MHCKMFAJ_01210 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MHCKMFAJ_01211 3.5e-168 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHCKMFAJ_01212 2.19e-12 - - - L ko:K07485 - ko00000 Transposase for ISSha1
MHCKMFAJ_01215 1.91e-08 vpr 3.4.21.96 - DO ko:K01361,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 PA domain
MHCKMFAJ_01219 1.98e-16 - - - K - - - Transcriptional regulator C-terminal region
MHCKMFAJ_01221 1.66e-53 - - - K - - - Acetyltransferase GNAT Family
MHCKMFAJ_01222 5.56e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
MHCKMFAJ_01223 2.05e-86 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MHCKMFAJ_01225 7.86e-140 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
MHCKMFAJ_01226 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MHCKMFAJ_01227 8.75e-60 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MHCKMFAJ_01228 3.21e-68 - - - K - - - Transcriptional regulator C-terminal region
MHCKMFAJ_01229 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
MHCKMFAJ_01230 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHCKMFAJ_01231 1.46e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
MHCKMFAJ_01232 1.71e-97 azlC - - E - - - branched-chain amino acid
MHCKMFAJ_01233 2.29e-75 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MHCKMFAJ_01234 3.49e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MHCKMFAJ_01235 7.76e-115 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHCKMFAJ_01236 7.5e-279 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCKMFAJ_01237 1.13e-278 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHCKMFAJ_01238 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MHCKMFAJ_01239 2.67e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MHCKMFAJ_01240 2.17e-240 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MHCKMFAJ_01241 1.85e-96 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MHCKMFAJ_01242 5.69e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MHCKMFAJ_01244 6.79e-263 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHCKMFAJ_01245 2.02e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
MHCKMFAJ_01246 3.63e-145 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
MHCKMFAJ_01247 2.16e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MHCKMFAJ_01248 1.4e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MHCKMFAJ_01249 1.7e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MHCKMFAJ_01250 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHCKMFAJ_01251 6.59e-219 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
MHCKMFAJ_01252 4.4e-257 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MHCKMFAJ_01253 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHCKMFAJ_01254 4.12e-236 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHCKMFAJ_01255 3.51e-58 - - - M - - - Glycosyl hydrolases family 25
MHCKMFAJ_01257 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCKMFAJ_01258 7.11e-129 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_01259 3.36e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MHCKMFAJ_01260 3.75e-49 - - - K - - - Transcriptional regulator
MHCKMFAJ_01261 6.4e-138 - - - P - - - Integral membrane protein TerC family
MHCKMFAJ_01262 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHCKMFAJ_01263 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHCKMFAJ_01264 2.44e-235 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MHCKMFAJ_01265 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
MHCKMFAJ_01266 1.09e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_01268 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
MHCKMFAJ_01269 1.64e-198 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHCKMFAJ_01270 1.57e-123 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHCKMFAJ_01271 6.07e-199 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHCKMFAJ_01272 3.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHCKMFAJ_01273 5e-45 - - - - - - - -
MHCKMFAJ_01274 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MHCKMFAJ_01275 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MHCKMFAJ_01276 8.86e-84 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MHCKMFAJ_01278 6.05e-94 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MHCKMFAJ_01279 1.36e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
MHCKMFAJ_01280 5.61e-102 - - - GM - - - NAD dependent epimerase dehydratase family protein
MHCKMFAJ_01281 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHCKMFAJ_01282 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHCKMFAJ_01283 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHCKMFAJ_01284 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MHCKMFAJ_01285 4.11e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHCKMFAJ_01286 4.12e-168 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHCKMFAJ_01287 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MHCKMFAJ_01288 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MHCKMFAJ_01289 1.18e-102 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCKMFAJ_01290 7.27e-111 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHCKMFAJ_01291 3.12e-79 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MHCKMFAJ_01292 7.54e-206 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHCKMFAJ_01293 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHCKMFAJ_01294 5.54e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
MHCKMFAJ_01295 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHCKMFAJ_01303 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MHCKMFAJ_01304 1.53e-234 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHCKMFAJ_01305 1.12e-198 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHCKMFAJ_01306 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MHCKMFAJ_01307 6.07e-152 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHCKMFAJ_01309 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MHCKMFAJ_01310 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHCKMFAJ_01311 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHCKMFAJ_01312 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHCKMFAJ_01313 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHCKMFAJ_01314 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHCKMFAJ_01315 7.68e-20 cvpA - - S - - - Colicin V production protein
MHCKMFAJ_01316 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHCKMFAJ_01317 7.02e-43 yrzB - - S - - - Belongs to the UPF0473 family
MHCKMFAJ_01318 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHCKMFAJ_01319 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
MHCKMFAJ_01320 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHCKMFAJ_01321 4.98e-235 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHCKMFAJ_01322 1.53e-154 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MHCKMFAJ_01323 3.5e-18 - - - - - - - -
MHCKMFAJ_01324 1.75e-183 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHCKMFAJ_01325 3.61e-84 lutC - - S ko:K00782 - ko00000 LUD domain
MHCKMFAJ_01326 2.34e-309 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
MHCKMFAJ_01327 7.13e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
MHCKMFAJ_01328 2.92e-264 - - - E ko:K03294 - ko00000 Amino Acid
MHCKMFAJ_01330 3.61e-79 uspA3 - - T - - - universal stress protein
MHCKMFAJ_01332 4.92e-20 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MHCKMFAJ_01333 3.35e-216 potE2 - - E ko:K03294 - ko00000 amino acid
MHCKMFAJ_01336 4.99e-114 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
MHCKMFAJ_01337 1.95e-122 - - - L - - - Type II restriction endonuclease, TdeIII
MHCKMFAJ_01338 6.24e-26 - - - K - - - Transcriptional
MHCKMFAJ_01339 6.1e-122 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 D12 class N6 adenine-specific DNA methyltransferase
MHCKMFAJ_01341 3.38e-296 - - - S ko:K06915 - ko00000 Domain of unknown function DUF87
MHCKMFAJ_01342 2.22e-117 - - - S - - - SIR2-like domain
MHCKMFAJ_01343 0.000777 yeeA - - V - - - Type II restriction enzyme, methylase subunits
MHCKMFAJ_01344 7.22e-85 - - - - - - - -
MHCKMFAJ_01345 2.85e-76 - - - - - - - -
MHCKMFAJ_01346 1.02e-205 - - - L - - - T/G mismatch-specific endonuclease activity
MHCKMFAJ_01348 3.2e-62 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MHCKMFAJ_01350 1.17e-72 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MHCKMFAJ_01351 1.38e-145 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHCKMFAJ_01352 1.4e-238 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHCKMFAJ_01353 3.18e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MHCKMFAJ_01354 7.17e-192 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHCKMFAJ_01355 3.13e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHCKMFAJ_01356 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHCKMFAJ_01357 7.57e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHCKMFAJ_01358 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHCKMFAJ_01359 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MHCKMFAJ_01360 5.39e-120 - - - M - - - Phosphotransferase enzyme family
MHCKMFAJ_01361 9.86e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MHCKMFAJ_01362 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MHCKMFAJ_01363 6.63e-21 - - - S - - - Protein of unknown function (DUF2969)
MHCKMFAJ_01364 2.29e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MHCKMFAJ_01365 2.82e-214 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MHCKMFAJ_01366 4.79e-42 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
MHCKMFAJ_01367 3.93e-87 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MHCKMFAJ_01368 4.08e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
MHCKMFAJ_01369 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MHCKMFAJ_01370 1.49e-93 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MHCKMFAJ_01371 4.83e-258 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHCKMFAJ_01372 4.65e-193 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHCKMFAJ_01373 2.68e-76 - - - G - - - Xylose isomerase domain protein TIM barrel
MHCKMFAJ_01374 4.37e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MHCKMFAJ_01375 5.05e-115 nanK - - GK - - - ROK family
MHCKMFAJ_01376 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MHCKMFAJ_01377 5.09e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MHCKMFAJ_01378 2.33e-95 - - - K - - - Helix-turn-helix domain, rpiR family
MHCKMFAJ_01379 1.31e-45 yphA - - GM - - - NAD dependent epimerase/dehydratase family
MHCKMFAJ_01380 8.18e-272 potE - - E - - - Amino Acid
MHCKMFAJ_01381 5.75e-09 - - - - - - - -
MHCKMFAJ_01382 3.83e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHCKMFAJ_01383 3.84e-280 fusA1 - - J - - - elongation factor G
MHCKMFAJ_01384 4.5e-255 XK26_06135 - - D - - - Plasmid recombination enzyme
MHCKMFAJ_01385 1.43e-307 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 Major Facilitator Superfamily
MHCKMFAJ_01386 0.0 XK27_03330 - - J ko:K18220 - br01600,ko00000,ko01504 elongation factor G
MHCKMFAJ_01387 0.0 - - - D ko:K03466 - ko00000,ko03036 Domain of unknown function DUF87
MHCKMFAJ_01388 1.39e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
MHCKMFAJ_01389 1.6e-69 - - - S - - - Bacterial protein of unknown function (DUF961)
MHCKMFAJ_01390 3.19e-59 tnpR1 - - L - - - Resolvase, N terminal domain
MHCKMFAJ_01394 1.37e-65 - - - L - - - Protein involved in initiation of plasmid replication
MHCKMFAJ_01395 8.62e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MHCKMFAJ_01396 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHCKMFAJ_01397 9.96e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHCKMFAJ_01398 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHCKMFAJ_01399 7.48e-284 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHCKMFAJ_01400 6.96e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MHCKMFAJ_01401 1.4e-95 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHCKMFAJ_01402 8.46e-293 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MHCKMFAJ_01403 5.32e-200 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MHCKMFAJ_01404 1.34e-113 - - - S - - - Acyltransferase family
MHCKMFAJ_01408 2.25e-34 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHCKMFAJ_01409 5.79e-84 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHCKMFAJ_01410 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MHCKMFAJ_01412 8.96e-47 - - - - - - - -
MHCKMFAJ_01413 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MHCKMFAJ_01414 3.83e-48 - - - - - - - -
MHCKMFAJ_01415 1.35e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHCKMFAJ_01416 1.24e-237 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
MHCKMFAJ_01417 5.12e-71 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MHCKMFAJ_01418 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHCKMFAJ_01419 3.02e-227 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_01420 9.69e-90 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHCKMFAJ_01423 1.91e-92 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
MHCKMFAJ_01424 8.46e-19 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
MHCKMFAJ_01425 1.76e-38 rusA - - L - - - Endodeoxyribonuclease RusA
MHCKMFAJ_01428 4.52e-10 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
MHCKMFAJ_01429 1.85e-40 - - - L - - - Helix-turn-helix domain
MHCKMFAJ_01430 5.29e-14 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHCKMFAJ_01432 6.99e-26 - - - - - - - -
MHCKMFAJ_01433 3.97e-80 - - - S - - - Putative HNHc nuclease
MHCKMFAJ_01434 1.75e-49 - - - S - - - ERF superfamily
MHCKMFAJ_01435 5.31e-10 - - - S - - - Bacteriophage Mu Gam like protein
MHCKMFAJ_01439 1.52e-59 - - - S - - - DNA binding
MHCKMFAJ_01440 4.5e-23 - - - K - - - Cro/C1-type HTH DNA-binding domain
MHCKMFAJ_01443 5.31e-18 - - - - - - - -
MHCKMFAJ_01445 4.5e-38 - - - S - - - sequence-specific DNA binding
MHCKMFAJ_01448 1.68e-17 - - - S - - - Hypothetical protein (DUF2513)
MHCKMFAJ_01449 1.16e-114 - - - L - - - Phage integrase, N-terminal SAM-like domain
MHCKMFAJ_01450 1.71e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHCKMFAJ_01451 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
MHCKMFAJ_01452 8.27e-221 - - - C - - - FMN_bind
MHCKMFAJ_01453 9.04e-70 oxyR5 - - K - - - Transcriptional regulator
MHCKMFAJ_01454 7e-201 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MHCKMFAJ_01455 3.6e-250 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MHCKMFAJ_01456 6.08e-95 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MHCKMFAJ_01457 3.69e-166 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
MHCKMFAJ_01458 5.1e-60 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MHCKMFAJ_01459 6.56e-73 yphH - - S - - - Cupin domain
MHCKMFAJ_01460 6.01e-60 - - - C - - - Flavodoxin
MHCKMFAJ_01461 4.1e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHCKMFAJ_01462 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
MHCKMFAJ_01463 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHCKMFAJ_01464 6.13e-286 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHCKMFAJ_01465 6.58e-70 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHCKMFAJ_01466 8.27e-86 yciB - - M - - - ErfK YbiS YcfS YnhG
MHCKMFAJ_01467 7e-139 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_01468 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHCKMFAJ_01469 9.18e-168 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MHCKMFAJ_01470 1.38e-200 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCKMFAJ_01471 1.26e-132 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHCKMFAJ_01472 3.16e-152 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_01473 8.99e-212 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHCKMFAJ_01474 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHCKMFAJ_01475 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MHCKMFAJ_01476 1.18e-295 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHCKMFAJ_01478 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MHCKMFAJ_01479 3.71e-09 - - - S - - - Putative adhesin
MHCKMFAJ_01480 2.01e-27 - - - S - - - Protein of unknown function (DUF1700)
MHCKMFAJ_01481 1.03e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
MHCKMFAJ_01482 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
MHCKMFAJ_01483 1.36e-96 ung2 - - L - - - Uracil-DNA glycosylase
MHCKMFAJ_01484 5.63e-207 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHCKMFAJ_01485 4.1e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHCKMFAJ_01486 4.25e-92 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MHCKMFAJ_01487 7.96e-68 - - - S - - - Domain of unknown function (DUF956)
MHCKMFAJ_01488 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHCKMFAJ_01489 1.69e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHCKMFAJ_01490 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHCKMFAJ_01491 3.08e-101 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
MHCKMFAJ_01492 2.16e-120 baeS - - T - - - Histidine kinase
MHCKMFAJ_01493 1.51e-101 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
MHCKMFAJ_01494 5.94e-148 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHCKMFAJ_01495 1.22e-89 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MHCKMFAJ_01496 9.06e-52 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCKMFAJ_01497 1.24e-43 - - - K - - - MerR HTH family regulatory protein
MHCKMFAJ_01498 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
MHCKMFAJ_01499 2.82e-42 - - - S - - - Domain of unknown function (DUF4811)
MHCKMFAJ_01500 2.88e-50 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHCKMFAJ_01501 5.39e-75 yceE - - S - - - haloacid dehalogenase-like hydrolase
MHCKMFAJ_01502 5.62e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHCKMFAJ_01503 2.69e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHCKMFAJ_01504 2.6e-230 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MHCKMFAJ_01505 7.69e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MHCKMFAJ_01506 3.21e-112 - - - S - - - Predicted membrane protein (DUF2207)
MHCKMFAJ_01507 4.02e-28 - - - - - - - -
MHCKMFAJ_01508 3.37e-16 epsJ2 - - S - - - Glycosyltransferase like family 2
MHCKMFAJ_01509 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MHCKMFAJ_01510 1.53e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
MHCKMFAJ_01511 1.2e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MHCKMFAJ_01512 1.37e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHCKMFAJ_01513 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHCKMFAJ_01514 5.21e-269 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MHCKMFAJ_01515 9.33e-186 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MHCKMFAJ_01516 3.11e-252 FbpA - - K - - - Fibronectin-binding protein
MHCKMFAJ_01517 2.07e-52 - - - K - - - Transcriptional regulator
MHCKMFAJ_01518 7.83e-144 - - - K - - - Primase C terminal 1 (PriCT-1)
MHCKMFAJ_01523 4.73e-05 - - - L - - - Transposase
MHCKMFAJ_01536 2.89e-22 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
MHCKMFAJ_01537 9.46e-50 - - - - - - - -
MHCKMFAJ_01542 3.44e-54 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MHCKMFAJ_01543 1.1e-30 - - - S - - - Cytochrome B5
MHCKMFAJ_01545 2.71e-80 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MHCKMFAJ_01546 5.45e-243 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHCKMFAJ_01547 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MHCKMFAJ_01548 7.08e-136 yueF - - S - - - AI-2E family transporter
MHCKMFAJ_01549 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MHCKMFAJ_01550 7.93e-146 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHCKMFAJ_01551 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHCKMFAJ_01552 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
MHCKMFAJ_01553 3.55e-61 - - - K - - - Acetyltransferase (GNAT) domain
MHCKMFAJ_01554 2.77e-19 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
MHCKMFAJ_01555 8.77e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHCKMFAJ_01556 1.13e-248 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MHCKMFAJ_01557 1.8e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MHCKMFAJ_01558 2.88e-53 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHCKMFAJ_01559 1.32e-204 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHCKMFAJ_01560 1.28e-76 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
MHCKMFAJ_01561 2.41e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
MHCKMFAJ_01562 6.67e-109 - - - M - - - Rib/alpha-like repeat
MHCKMFAJ_01563 8.57e-36 - - - M - - - Rib/alpha-like repeat
MHCKMFAJ_01566 5.38e-10 - - - L - - - Transposase
MHCKMFAJ_01567 1.77e-142 - - - L - - - Transposase
MHCKMFAJ_01568 8.61e-258 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCKMFAJ_01569 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_01570 1.83e-41 - - - - - - - -
MHCKMFAJ_01571 2.05e-138 ampC - - V - - - Beta-lactamase
MHCKMFAJ_01572 9.35e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MHCKMFAJ_01573 5.14e-278 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MHCKMFAJ_01574 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MHCKMFAJ_01575 1.04e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHCKMFAJ_01576 7.51e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHCKMFAJ_01577 5.45e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHCKMFAJ_01578 2.18e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHCKMFAJ_01581 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MHCKMFAJ_01582 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHCKMFAJ_01583 1.24e-260 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MHCKMFAJ_01584 9.78e-82 - - - C - - - FMN binding
MHCKMFAJ_01585 2.37e-290 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHCKMFAJ_01587 1.22e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHCKMFAJ_01588 6.98e-78 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
MHCKMFAJ_01589 7.94e-14 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
MHCKMFAJ_01590 3.14e-104 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MHCKMFAJ_01591 3.19e-114 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MHCKMFAJ_01592 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHCKMFAJ_01593 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHCKMFAJ_01594 1.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
MHCKMFAJ_01595 2.27e-87 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHCKMFAJ_01596 1.33e-108 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHCKMFAJ_01600 2.32e-165 - - - M - - - Glycosyl hydrolases family 25
MHCKMFAJ_01601 5.06e-14 - - - S - - - Bacteriophage holin
MHCKMFAJ_01608 3.14e-34 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MHCKMFAJ_01609 1.16e-06 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
MHCKMFAJ_01610 1.53e-26 - - - S ko:K07065 - ko00000 Toxic component of a toxin-antitoxin (TA) module. An RNase
MHCKMFAJ_01614 3.88e-70 - - - V - - - Type I restriction modification DNA specificity domain
MHCKMFAJ_01616 3.19e-40 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHCKMFAJ_01617 1.21e-195 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MHCKMFAJ_01618 1.86e-76 bcgIB 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K03427 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
MHCKMFAJ_01620 1.97e-20 - - - D - - - nuclear chromosome segregation
MHCKMFAJ_01622 2.83e-26 - - - K - - - Psort location Cytoplasmic, score
MHCKMFAJ_01623 1.4e-141 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
MHCKMFAJ_01624 3.32e-105 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
MHCKMFAJ_01625 1.2e-110 - - - EG - - - EamA-like transporter family
MHCKMFAJ_01626 2.25e-88 - - - S - - - Calcineurin-like phosphoesterase
MHCKMFAJ_01627 8.2e-108 sip - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_01628 2.76e-128 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
MHCKMFAJ_01629 9.8e-87 - - - S - - - AAA ATPase domain
MHCKMFAJ_01631 7.41e-17 - - - - - - - -
MHCKMFAJ_01632 2.24e-23 - - - L - - - nuclease
MHCKMFAJ_01633 5.12e-36 - - - S - - - Short C-terminal domain
MHCKMFAJ_01635 1.18e-29 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MHCKMFAJ_01636 2.7e-130 - - - G - - - MucBP domain
MHCKMFAJ_01637 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MHCKMFAJ_01638 1.15e-250 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MHCKMFAJ_01639 1.26e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHCKMFAJ_01640 8.74e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHCKMFAJ_01641 2.26e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHCKMFAJ_01642 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MHCKMFAJ_01643 1.02e-08 - - - - - - - -
MHCKMFAJ_01645 5.46e-162 - - - S ko:K06919 - ko00000 D5 N terminal like
MHCKMFAJ_01646 1.06e-23 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
MHCKMFAJ_01653 2.23e-57 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
MHCKMFAJ_01655 9.14e-46 - - - K - - - Helix-turn-helix XRE-family like proteins
MHCKMFAJ_01657 1.13e-146 - - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_01658 8.07e-120 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MHCKMFAJ_01659 2.24e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
MHCKMFAJ_01660 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHCKMFAJ_01661 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MHCKMFAJ_01662 2.04e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MHCKMFAJ_01663 3.97e-69 gtcA - - S - - - Teichoic acid glycosylation protein
MHCKMFAJ_01664 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
MHCKMFAJ_01665 4.44e-98 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
MHCKMFAJ_01666 3.37e-27 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
MHCKMFAJ_01667 2.54e-232 - - - L - - - Probable transposase
MHCKMFAJ_01668 4.15e-47 - - - S - - - Sulfite exporter TauE/SafE
MHCKMFAJ_01669 4.88e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
MHCKMFAJ_01670 5.08e-213 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHCKMFAJ_01671 7.04e-229 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
MHCKMFAJ_01672 1.49e-11 - - - E - - - Amino acid permease
MHCKMFAJ_01673 1.16e-313 - - - E - - - Amino acid permease
MHCKMFAJ_01674 1.29e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MHCKMFAJ_01675 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MHCKMFAJ_01676 9.55e-96 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MHCKMFAJ_01677 3.51e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
MHCKMFAJ_01678 1.64e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
MHCKMFAJ_01679 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MHCKMFAJ_01682 9.82e-202 yfmL - - L - - - DEAD DEAH box helicase
MHCKMFAJ_01683 3.09e-160 mocA - - S - - - Oxidoreductase
MHCKMFAJ_01684 1.13e-32 - - - S - - - Domain of unknown function (DUF4828)
MHCKMFAJ_01685 9.89e-215 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHCKMFAJ_01686 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHCKMFAJ_01687 6.37e-244 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHCKMFAJ_01688 7.84e-157 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MHCKMFAJ_01689 2.38e-209 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHCKMFAJ_01690 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHCKMFAJ_01691 1.03e-272 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHCKMFAJ_01692 1.47e-45 - - - O - - - ADP-ribosylglycohydrolase
MHCKMFAJ_01693 5.08e-278 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MHCKMFAJ_01694 5.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHCKMFAJ_01695 1.32e-41 - - - K - - - GNAT family
MHCKMFAJ_01696 1.96e-54 - - - - - - - -
MHCKMFAJ_01698 5.17e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
MHCKMFAJ_01699 1.13e-116 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHCKMFAJ_01700 1.79e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHCKMFAJ_01701 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MHCKMFAJ_01702 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHCKMFAJ_01703 6.03e-51 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHCKMFAJ_01704 6.35e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MHCKMFAJ_01705 5.57e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHCKMFAJ_01706 7.37e-77 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MHCKMFAJ_01707 4.02e-82 - - - S - - - ECF transporter, substrate-specific component
MHCKMFAJ_01708 3.55e-161 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MHCKMFAJ_01709 9.73e-313 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MHCKMFAJ_01710 1.13e-89 mleR - - K - - - LysR family
MHCKMFAJ_01711 3.65e-74 napB - - K - - - transcriptional
MHCKMFAJ_01712 1.17e-52 - - - K - - - Bacterial regulatory proteins, tetR family
MHCKMFAJ_01713 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
MHCKMFAJ_01714 2.15e-59 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MHCKMFAJ_01716 1.06e-28 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
MHCKMFAJ_01717 2.69e-147 - - - M - - - Glycosyl hydrolases family 25
MHCKMFAJ_01718 1.82e-49 - - - - - - - -
MHCKMFAJ_01719 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MHCKMFAJ_01720 1.89e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHCKMFAJ_01721 3.15e-200 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHCKMFAJ_01722 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHCKMFAJ_01723 4.68e-137 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHCKMFAJ_01725 1.46e-141 csrR - - K - - - response regulator
MHCKMFAJ_01726 1.09e-218 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHCKMFAJ_01727 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHCKMFAJ_01728 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHCKMFAJ_01729 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MHCKMFAJ_01730 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHCKMFAJ_01731 2.76e-175 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MHCKMFAJ_01733 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHCKMFAJ_01734 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MHCKMFAJ_01735 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MHCKMFAJ_01736 7.15e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MHCKMFAJ_01737 8.83e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHCKMFAJ_01738 7e-134 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MHCKMFAJ_01739 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHCKMFAJ_01740 4.26e-277 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
MHCKMFAJ_01741 1.34e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MHCKMFAJ_01742 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MHCKMFAJ_01743 1.06e-243 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MHCKMFAJ_01744 1.11e-231 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHCKMFAJ_01745 1.22e-175 - - - V - - - Pfam:Methyltransf_26
MHCKMFAJ_01748 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHCKMFAJ_01749 1.35e-262 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHCKMFAJ_01750 1.09e-20 - - - S - - - Protein of unknown function (DUF805)
MHCKMFAJ_01751 1.04e-59 - - - L - - - PLD-like domain
MHCKMFAJ_01752 7.27e-63 - - - L - - - PLD-like domain
MHCKMFAJ_01754 7.96e-143 - - - L - - - Initiator Replication protein
MHCKMFAJ_01755 1.88e-45 - - - S - - - Replication initiator protein A (RepA) N-terminus
MHCKMFAJ_01756 9.66e-180 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHCKMFAJ_01757 5.35e-288 - - - L - - - Probable transposase
MHCKMFAJ_01758 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHCKMFAJ_01759 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHCKMFAJ_01760 1.24e-47 - - - S - - - Enterocin A Immunity
MHCKMFAJ_01761 8.37e-103 yitS - - S - - - EDD domain protein, DegV family
MHCKMFAJ_01762 3.77e-74 - - - K - - - Domain of unknown function (DUF1836)
MHCKMFAJ_01763 7.79e-148 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MHCKMFAJ_01764 4.06e-30 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MHCKMFAJ_01765 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHCKMFAJ_01766 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHCKMFAJ_01767 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHCKMFAJ_01768 4.67e-117 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MHCKMFAJ_01769 7.86e-106 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHCKMFAJ_01770 1.21e-145 vanR - - K - - - response regulator
MHCKMFAJ_01771 5.29e-191 hpk31 - - T - - - Histidine kinase
MHCKMFAJ_01773 3.53e-230 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MHCKMFAJ_01774 6.22e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
MHCKMFAJ_01775 3.29e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHCKMFAJ_01776 2.28e-283 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHCKMFAJ_01777 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHCKMFAJ_01778 1.44e-179 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHCKMFAJ_01780 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MHCKMFAJ_01787 1.74e-103 - - - K - - - Penicillinase repressor
MHCKMFAJ_01788 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 haloacid dehalogenase-like hydrolase
MHCKMFAJ_01789 1.4e-53 - - - S ko:K08982 - ko00000 membrane protein (DUF2078)
MHCKMFAJ_01790 5.25e-22 - - - S - - - Domain of unknown function DUF302
MHCKMFAJ_01791 1.61e-44 - - - S - - - Domain of unknown function DUF302
MHCKMFAJ_01792 3.15e-56 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHCKMFAJ_01793 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MHCKMFAJ_01794 2.25e-170 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MHCKMFAJ_01795 2.88e-56 - - - E - - - GDSL-like Lipase/Acylhydrolase
MHCKMFAJ_01796 3.91e-143 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_01797 1.41e-240 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_01798 1.21e-20 - - - - - - - -
MHCKMFAJ_01800 5.56e-89 - - - - - - - -
MHCKMFAJ_01801 1.94e-124 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MHCKMFAJ_01802 3.66e-224 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MHCKMFAJ_01803 5.15e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MHCKMFAJ_01804 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHCKMFAJ_01805 6.04e-275 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHCKMFAJ_01806 4.82e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHCKMFAJ_01807 2.77e-75 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHCKMFAJ_01808 3.83e-79 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHCKMFAJ_01809 2.3e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHCKMFAJ_01810 6.23e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHCKMFAJ_01811 1.16e-67 - - - S - - - Protein of unknown function (DUF441)
MHCKMFAJ_01812 3.06e-159 yitL - - S ko:K00243 - ko00000 S1 domain
MHCKMFAJ_01813 1.39e-142 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MHCKMFAJ_01814 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MHCKMFAJ_01815 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHCKMFAJ_01816 5.33e-237 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MHCKMFAJ_01817 3.94e-84 ypsA - - S - - - Belongs to the UPF0398 family
MHCKMFAJ_01818 2.09e-246 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
MHCKMFAJ_01820 1.59e-91 - - - M - - - GNAT acetyltransferase
MHCKMFAJ_01821 1.64e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHCKMFAJ_01822 1.34e-73 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MHCKMFAJ_01823 6.87e-103 - - - F - - - Hydrolase, nudix family
MHCKMFAJ_01825 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MHCKMFAJ_01826 9.72e-259 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MHCKMFAJ_01827 7.51e-118 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MHCKMFAJ_01828 1.9e-166 - - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_01829 5.16e-83 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I Restriction
MHCKMFAJ_01830 6.98e-96 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MHCKMFAJ_01831 4.22e-87 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHCKMFAJ_01832 1.33e-135 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
MHCKMFAJ_01833 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MHCKMFAJ_01834 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MHCKMFAJ_01835 6.27e-264 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHCKMFAJ_01836 7.63e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHCKMFAJ_01837 2.54e-276 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHCKMFAJ_01838 5.3e-80 - - - S - - - Helix-turn-helix domain
MHCKMFAJ_01839 2.63e-155 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MHCKMFAJ_01840 9.02e-28 - - - M - - - Lysin motif
MHCKMFAJ_01841 1.02e-111 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MHCKMFAJ_01842 7.33e-107 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
MHCKMFAJ_01843 5.08e-197 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MHCKMFAJ_01844 2.42e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHCKMFAJ_01845 4.18e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MHCKMFAJ_01846 4.63e-199 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHCKMFAJ_01847 6.69e-115 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MHCKMFAJ_01849 1.25e-275 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCKMFAJ_01850 1.94e-222 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MHCKMFAJ_01851 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHCKMFAJ_01852 3.32e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHCKMFAJ_01853 1.66e-76 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
MHCKMFAJ_01854 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MHCKMFAJ_01855 3.35e-288 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MHCKMFAJ_01856 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHCKMFAJ_01857 3.44e-169 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MHCKMFAJ_01858 2.96e-75 radC - - L ko:K03630 - ko00000 DNA repair protein
MHCKMFAJ_01859 1.19e-259 - - - L ko:K04763 - ko00000,ko03036 similarity to EGAD 7942
MHCKMFAJ_01860 0.0 - - - L - - - similarity to EGAD 8390
MHCKMFAJ_01861 5.94e-75 - - - S - - - similarity to EGAD 6135
MHCKMFAJ_01862 9.06e-186 - - - S ko:K19279 - ko00000,ko01000,ko01504 Domain of unknown function (DUF4111)
MHCKMFAJ_01863 5.08e-111 ermA 2.1.1.184 - J ko:K00561 - br01600,ko00000,ko01000,ko01504,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
MHCKMFAJ_01864 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MHCKMFAJ_01865 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHCKMFAJ_01866 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHCKMFAJ_01867 2.82e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHCKMFAJ_01868 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHCKMFAJ_01869 9.43e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHCKMFAJ_01870 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHCKMFAJ_01871 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MHCKMFAJ_01873 3.59e-60 - - - S - - - Short repeat of unknown function (DUF308)
MHCKMFAJ_01874 7.92e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHCKMFAJ_01875 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MHCKMFAJ_01876 4.78e-86 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
MHCKMFAJ_01877 1.03e-129 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MHCKMFAJ_01878 8.21e-56 - - - K - - - HxlR-like helix-turn-helix
MHCKMFAJ_01879 3.68e-151 ytbE - - S - - - reductase
MHCKMFAJ_01880 1.84e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHCKMFAJ_01881 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHCKMFAJ_01882 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
MHCKMFAJ_01883 2.92e-164 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHCKMFAJ_01884 2.61e-163 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHCKMFAJ_01885 5.16e-203 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHCKMFAJ_01886 1.8e-33 - - - L - - - Transposase
MHCKMFAJ_01888 1.98e-80 - - - S - - - Acetyltransferase (GNAT) domain
MHCKMFAJ_01889 2.94e-91 ywlG - - S - - - Belongs to the UPF0340 family
MHCKMFAJ_01890 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MHCKMFAJ_01891 2.11e-122 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHCKMFAJ_01892 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHCKMFAJ_01893 3.99e-91 - - - C - - - Domain of unknown function (DUF4931)
MHCKMFAJ_01894 0.000269 - - - C - - - galactose-1-phosphate uridylyltransferase
MHCKMFAJ_01895 2.6e-114 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MHCKMFAJ_01896 1.8e-67 - - - M - - - LysM domain protein
MHCKMFAJ_01897 1.38e-25 - - - P - - - Rhodanese Homology Domain
MHCKMFAJ_01898 5.53e-49 - - - M - - - LysM domain
MHCKMFAJ_01899 4.68e-203 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MHCKMFAJ_01901 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MHCKMFAJ_01902 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHCKMFAJ_01903 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHCKMFAJ_01904 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHCKMFAJ_01905 7.83e-85 - - - D - - - Peptidase family M23
MHCKMFAJ_01907 4.91e-172 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
MHCKMFAJ_01908 1.24e-43 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
MHCKMFAJ_01909 3.61e-268 potE - - E - - - Amino Acid
MHCKMFAJ_01910 5.91e-61 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHCKMFAJ_01911 1.92e-176 - - - E - - - Beta-eliminating lyase
MHCKMFAJ_01912 3.15e-114 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHCKMFAJ_01913 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
MHCKMFAJ_01914 3.1e-168 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHCKMFAJ_01915 4.87e-112 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHCKMFAJ_01916 2.97e-132 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MHCKMFAJ_01917 2.61e-21 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MHCKMFAJ_01918 7.49e-262 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
MHCKMFAJ_01919 4.6e-145 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MHCKMFAJ_01920 7.07e-53 - - - K - - - LytTr DNA-binding domain
MHCKMFAJ_01922 1.31e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MHCKMFAJ_01923 7.99e-16 - - - K - - - Transcriptional regulator C-terminal region
MHCKMFAJ_01924 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHCKMFAJ_01925 1.71e-136 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHCKMFAJ_01926 8.69e-62 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHCKMFAJ_01927 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHCKMFAJ_01928 4.39e-96 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MHCKMFAJ_01929 5.69e-137 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MHCKMFAJ_01930 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHCKMFAJ_01931 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHCKMFAJ_01932 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MHCKMFAJ_01933 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHCKMFAJ_01934 2.34e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MHCKMFAJ_01935 5.09e-230 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MHCKMFAJ_01936 9.56e-41 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MHCKMFAJ_01937 7.07e-99 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHCKMFAJ_01938 1.33e-88 yqeK - - H - - - Hydrolase, HD family
MHCKMFAJ_01939 4.81e-66 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHCKMFAJ_01940 1.86e-103 - - - H - - - Nodulation protein S (NodS)
MHCKMFAJ_01941 3.25e-153 ylbM - - S - - - Belongs to the UPF0348 family
MHCKMFAJ_01942 3.18e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MHCKMFAJ_01943 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MHCKMFAJ_01944 3.48e-114 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MHCKMFAJ_01945 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MHCKMFAJ_01946 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MHCKMFAJ_01947 2e-171 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MHCKMFAJ_01948 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHCKMFAJ_01949 6.66e-98 - - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_01950 7.96e-39 - - - - - - - -
MHCKMFAJ_01951 2.16e-33 - - - S - - - Domain of unknown function (DUF4352)
MHCKMFAJ_01952 6.75e-49 - - - E - - - IrrE N-terminal-like domain
MHCKMFAJ_01953 3.84e-57 - - - K ko:K07727 - ko00000,ko03000 addiction module antidote protein HigA
MHCKMFAJ_01954 1.65e-19 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
MHCKMFAJ_01955 1.93e-26 - - - - - - - -
MHCKMFAJ_01961 3.44e-206 - - - D - - - AAA domain
MHCKMFAJ_01962 5.21e-134 - - - S - - - AAA domain
MHCKMFAJ_01963 1.52e-64 - - - - - - - -
MHCKMFAJ_01964 1.15e-52 - - - - - - - -
MHCKMFAJ_01965 3.03e-104 - - - - - - - -
MHCKMFAJ_01966 0.0 - - - L - - - Helicase C-terminal domain protein
MHCKMFAJ_01967 0.0 - - - L - - - Primase C terminal 2 (PriCT-2)
MHCKMFAJ_01968 5.62e-59 - - - S - - - magnesium ion binding
MHCKMFAJ_01977 1.08e-27 - - - - - - - -
MHCKMFAJ_01978 2.77e-207 - - - S - - - Pfam:Terminase_3C
MHCKMFAJ_01979 1.09e-176 - - - S - - - Phage portal protein, SPP1 Gp6-like
MHCKMFAJ_01980 4.09e-113 - - - S - - - Phage minor capsid protein 2
MHCKMFAJ_01983 7.04e-06 - - - S - - - Phage minor structural protein GP20
MHCKMFAJ_01984 0.000383 - - - S - - - Phage minor structural protein GP20
MHCKMFAJ_01985 2.49e-123 - - - S - - - T=7 icosahedral viral capsid
MHCKMFAJ_01987 1.07e-38 - - - S - - - Minor capsid protein
MHCKMFAJ_01990 6.69e-50 - - - N - - - domain, Protein
MHCKMFAJ_01992 3.88e-50 - - - S - - - Bacteriophage Gp15 protein
MHCKMFAJ_01993 4.38e-111 - - - L - - - Phage tail tape measure protein TP901
MHCKMFAJ_01995 3.6e-115 - - - M - - - Prophage endopeptidase tail
MHCKMFAJ_01998 1.55e-05 - - - N - - - Bacterial Ig-like domain 2
MHCKMFAJ_02003 1.27e-52 - - - S - - - Bacteriophage holin family
MHCKMFAJ_02004 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MHCKMFAJ_02005 1.5e-22 - - - - - - - -
MHCKMFAJ_02006 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MHCKMFAJ_02007 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHCKMFAJ_02017 4.29e-115 yunF - - F - - - Protein of unknown function DUF72
MHCKMFAJ_02018 3.45e-198 yngD - - S ko:K07097 - ko00000 DHHA1 domain
MHCKMFAJ_02019 1.8e-56 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MHCKMFAJ_02020 8.28e-75 - - - - - - - -
MHCKMFAJ_02021 2.17e-165 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHCKMFAJ_02022 3.41e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHCKMFAJ_02023 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MHCKMFAJ_02024 2.2e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCKMFAJ_02025 4.07e-213 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHCKMFAJ_02026 1.88e-18 - - - - - - - -
MHCKMFAJ_02027 2.45e-132 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_02028 3.96e-125 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHCKMFAJ_02029 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_02030 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_02031 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MHCKMFAJ_02032 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MHCKMFAJ_02033 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MHCKMFAJ_02036 8.46e-72 - - - V - - - endonuclease activity
MHCKMFAJ_02039 3.24e-90 - - - O - - - ADP-ribosylglycohydrolase
MHCKMFAJ_02040 4.52e-131 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHCKMFAJ_02041 1.68e-305 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MHCKMFAJ_02043 1.2e-83 - - - L - - - Belongs to the 'phage' integrase family
MHCKMFAJ_02044 1.91e-17 - - - S - - - Acyltransferase family
MHCKMFAJ_02045 1.38e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHCKMFAJ_02046 7.02e-157 - - - K - - - LysR substrate binding domain
MHCKMFAJ_02048 6.94e-28 - - - - - - - -
MHCKMFAJ_02049 4.58e-73 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHCKMFAJ_02050 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MHCKMFAJ_02051 7.31e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MHCKMFAJ_02052 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MHCKMFAJ_02053 1.24e-186 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MHCKMFAJ_02054 1.79e-134 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MHCKMFAJ_02055 3.76e-143 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHCKMFAJ_02056 6.58e-172 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MHCKMFAJ_02057 2.07e-155 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MHCKMFAJ_02058 5.52e-121 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MHCKMFAJ_02059 2.58e-269 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MHCKMFAJ_02060 1.35e-46 ypmB - - S - - - Protein conserved in bacteria
MHCKMFAJ_02061 9.06e-181 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHCKMFAJ_02062 4.9e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MHCKMFAJ_02063 5.71e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MHCKMFAJ_02064 3.11e-108 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHCKMFAJ_02065 7.32e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHCKMFAJ_02066 6.17e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHCKMFAJ_02067 2.22e-114 - - - M - - - transferase activity, transferring glycosyl groups
MHCKMFAJ_02068 3.47e-106 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MHCKMFAJ_02069 3.08e-126 - - - M - - - Glycosyltransferase like family 2
MHCKMFAJ_02072 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHCKMFAJ_02073 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MHCKMFAJ_02074 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MHCKMFAJ_02076 5.44e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
MHCKMFAJ_02077 1.89e-142 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHCKMFAJ_02078 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHCKMFAJ_02079 2.05e-167 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHCKMFAJ_02080 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_02081 1.36e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHCKMFAJ_02082 7.15e-72 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHCKMFAJ_02083 2.42e-169 - - - C - - - Aldo keto reductase
MHCKMFAJ_02084 6.42e-32 - - - K - - - regulatory protein
MHCKMFAJ_02085 7.2e-142 ydhF - - S - - - Aldo keto reductase
MHCKMFAJ_02087 2.14e-99 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MHCKMFAJ_02088 7.98e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MHCKMFAJ_02089 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
MHCKMFAJ_02090 2.54e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHCKMFAJ_02091 1.67e-123 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHCKMFAJ_02092 4.44e-41 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MHCKMFAJ_02093 1.13e-103 - - - L - - - Transposase, IS116 IS110 IS902 family
MHCKMFAJ_02094 3.28e-67 - - - - - - - -
MHCKMFAJ_02095 6.43e-80 - - - M - - - LPXTG-motif cell wall anchor domain protein
MHCKMFAJ_02096 1.11e-64 - - - M - - - LPXTG-motif cell wall anchor domain protein
MHCKMFAJ_02097 5.74e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHCKMFAJ_02098 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MHCKMFAJ_02099 1.15e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHCKMFAJ_02100 5.17e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MHCKMFAJ_02101 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHCKMFAJ_02102 3.53e-94 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MHCKMFAJ_02103 2.86e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MHCKMFAJ_02104 1.08e-117 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
MHCKMFAJ_02105 1.63e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MHCKMFAJ_02106 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
MHCKMFAJ_02110 4.77e-193 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHCKMFAJ_02111 7.68e-120 - - - J - - - Aminoglycoside-2''-adenylyltransferase
MHCKMFAJ_02113 3.28e-114 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MHCKMFAJ_02114 8.56e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
MHCKMFAJ_02115 4.52e-129 yvgN - - C - - - Aldo keto reductase
MHCKMFAJ_02116 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHCKMFAJ_02117 3.54e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MHCKMFAJ_02118 3.24e-118 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHCKMFAJ_02119 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
MHCKMFAJ_02120 4.86e-27 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MHCKMFAJ_02121 1.1e-42 yabO - - J - - - S4 domain protein
MHCKMFAJ_02122 2.32e-173 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHCKMFAJ_02123 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHCKMFAJ_02124 1.45e-95 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHCKMFAJ_02125 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MHCKMFAJ_02126 2.56e-109 - - - S - - - (CBS) domain
MHCKMFAJ_02127 3.13e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHCKMFAJ_02128 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHCKMFAJ_02129 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MHCKMFAJ_02130 1.65e-72 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MHCKMFAJ_02131 5.31e-126 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MHCKMFAJ_02132 3.79e-145 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHCKMFAJ_02133 8.4e-66 - - - M - - - LysM domain protein
MHCKMFAJ_02134 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHCKMFAJ_02135 3.17e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MHCKMFAJ_02136 2.1e-41 - - - K - - - transcriptional regulator (TetR family)
MHCKMFAJ_02137 1.62e-139 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHCKMFAJ_02138 1.81e-110 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHCKMFAJ_02139 1.79e-86 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MHCKMFAJ_02140 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHCKMFAJ_02141 5.67e-307 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MHCKMFAJ_02143 1.32e-78 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MHCKMFAJ_02144 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHCKMFAJ_02145 1.08e-160 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHCKMFAJ_02146 1.08e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHCKMFAJ_02147 2.51e-139 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHCKMFAJ_02148 2.78e-128 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHCKMFAJ_02149 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MHCKMFAJ_02150 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHCKMFAJ_02151 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHCKMFAJ_02152 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHCKMFAJ_02153 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MHCKMFAJ_02154 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHCKMFAJ_02155 3.12e-143 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHCKMFAJ_02156 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHCKMFAJ_02157 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHCKMFAJ_02158 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MHCKMFAJ_02159 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHCKMFAJ_02160 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHCKMFAJ_02161 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHCKMFAJ_02162 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHCKMFAJ_02163 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHCKMFAJ_02164 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHCKMFAJ_02165 3.84e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHCKMFAJ_02166 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHCKMFAJ_02167 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHCKMFAJ_02168 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MHCKMFAJ_02169 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHCKMFAJ_02170 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHCKMFAJ_02171 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHCKMFAJ_02172 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHCKMFAJ_02173 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHCKMFAJ_02174 1.34e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHCKMFAJ_02175 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MHCKMFAJ_02176 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHCKMFAJ_02177 7.65e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MHCKMFAJ_02178 3.47e-217 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHCKMFAJ_02179 1.44e-94 - - - K - - - rpiR family
MHCKMFAJ_02180 1.77e-38 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MHCKMFAJ_02181 4.58e-185 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MHCKMFAJ_02182 2.79e-14 - - - K - - - Acetyltransferase (GNAT) domain
MHCKMFAJ_02183 8.22e-240 steT - - E ko:K03294 - ko00000 amino acid

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)