ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LAPPPGAB_00001 1.33e-53 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LAPPPGAB_00002 1.36e-78 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Possible lysine decarboxylase
LAPPPGAB_00015 5.89e-44 - - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
LAPPPGAB_00017 3.41e-05 - 3.1.1.11 - G ko:K01051 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Pectinesterase
LAPPPGAB_00024 5.06e-14 - - - S - - - Bacteriophage holin
LAPPPGAB_00025 1.47e-166 - - - M - - - Glycosyl hydrolases family 25
LAPPPGAB_00029 2.32e-109 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LAPPPGAB_00030 1.95e-88 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LAPPPGAB_00031 1.97e-56 yodB - - K - - - Transcriptional regulator, HxlR family
LAPPPGAB_00032 7.45e-220 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LAPPPGAB_00033 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LAPPPGAB_00034 1.15e-163 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LAPPPGAB_00035 4.31e-127 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LAPPPGAB_00036 2e-88 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LAPPPGAB_00037 5.6e-17 - - - - - - - -
LAPPPGAB_00038 1.24e-183 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
LAPPPGAB_00039 6.01e-55 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
LAPPPGAB_00040 1.46e-147 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
LAPPPGAB_00041 1.52e-97 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LAPPPGAB_00042 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LAPPPGAB_00043 7.24e-71 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LAPPPGAB_00044 8.95e-73 yjcF - - J - - - HAD-hyrolase-like
LAPPPGAB_00045 4.45e-55 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LAPPPGAB_00046 3.96e-163 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LAPPPGAB_00047 2.49e-97 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LAPPPGAB_00048 1.07e-256 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
LAPPPGAB_00049 2.6e-141 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LAPPPGAB_00050 7.36e-238 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LAPPPGAB_00051 1.5e-109 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LAPPPGAB_00052 7.08e-113 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LAPPPGAB_00053 1.34e-172 - - - K - - - Transcriptional regulator
LAPPPGAB_00054 7.65e-185 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
LAPPPGAB_00055 1.16e-147 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LAPPPGAB_00056 4.96e-219 araT1 - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LAPPPGAB_00057 2.01e-110 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LAPPPGAB_00059 3.6e-57 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LAPPPGAB_00060 3.81e-218 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LAPPPGAB_00061 6.27e-48 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
LAPPPGAB_00062 4.15e-34 - - - S - - - Family of unknown function (DUF5322)
LAPPPGAB_00063 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
LAPPPGAB_00064 8.73e-51 - - - - - - - -
LAPPPGAB_00066 4.13e-185 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
LAPPPGAB_00067 6.85e-98 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LAPPPGAB_00068 5.44e-130 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LAPPPGAB_00069 1.76e-232 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LAPPPGAB_00070 3.58e-23 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
LAPPPGAB_00071 4.97e-140 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LAPPPGAB_00072 1.56e-257 ynbB - - P - - - aluminum resistance
LAPPPGAB_00073 1.3e-59 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
LAPPPGAB_00074 3.28e-312 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LAPPPGAB_00076 6.13e-47 - 2.1.1.63 - H ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LAPPPGAB_00077 8.28e-64 manO - - S - - - Domain of unknown function (DUF956)
LAPPPGAB_00078 1.02e-147 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LAPPPGAB_00079 8.26e-105 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LAPPPGAB_00080 2.86e-134 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LAPPPGAB_00081 1.58e-131 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LAPPPGAB_00082 2.52e-196 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LAPPPGAB_00083 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LAPPPGAB_00084 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LAPPPGAB_00085 1.16e-85 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LAPPPGAB_00086 1.25e-216 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LAPPPGAB_00087 3.32e-53 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
LAPPPGAB_00088 4.38e-35 ylxQ - - J - - - ribosomal protein
LAPPPGAB_00089 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LAPPPGAB_00090 6.33e-74 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LAPPPGAB_00091 1.16e-151 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LAPPPGAB_00092 7.4e-120 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LAPPPGAB_00093 1.51e-165 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LAPPPGAB_00094 3.65e-75 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LAPPPGAB_00095 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LAPPPGAB_00096 5.74e-218 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LAPPPGAB_00097 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LAPPPGAB_00099 8.61e-258 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LAPPPGAB_00100 7.44e-153 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00101 1.83e-41 - - - - - - - -
LAPPPGAB_00102 2.05e-138 ampC - - V - - - Beta-lactamase
LAPPPGAB_00103 9.35e-141 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
LAPPPGAB_00104 5.14e-278 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
LAPPPGAB_00105 1.19e-111 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LAPPPGAB_00106 1.04e-230 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LAPPPGAB_00107 7.51e-114 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LAPPPGAB_00108 1.9e-171 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LAPPPGAB_00109 2.18e-129 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LAPPPGAB_00110 2.33e-124 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LAPPPGAB_00111 1.39e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LAPPPGAB_00112 2.96e-57 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LAPPPGAB_00113 2.82e-74 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LAPPPGAB_00114 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LAPPPGAB_00115 9.43e-181 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LAPPPGAB_00116 8.04e-313 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LAPPPGAB_00117 6.22e-70 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LAPPPGAB_00118 2.44e-40 - - - L ko:K07491 - ko00000 Transposase IS200 like
LAPPPGAB_00119 1.65e-108 - - - F - - - glutamine amidotransferase
LAPPPGAB_00120 6.95e-261 ywfO - - S ko:K06885 - ko00000 HD domain protein
LAPPPGAB_00121 3.53e-111 - - - S - - - hydrolase
LAPPPGAB_00122 4.07e-130 - - - S ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Putative inner membrane exporter, YdcZ
LAPPPGAB_00123 8.64e-24 - - - - - - - -
LAPPPGAB_00124 6.62e-91 - - - - - - - -
LAPPPGAB_00126 4.79e-25 recD2_2 3.1.11.5 - L ko:K01144 - ko00000,ko01000 PIF1-like helicase
LAPPPGAB_00128 2.97e-63 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
LAPPPGAB_00130 3.33e-110 - - - S - - - overlaps another CDS with the same product name
LAPPPGAB_00131 4.53e-156 yibE - - S - - - overlaps another CDS with the same product name
LAPPPGAB_00132 3.51e-124 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LAPPPGAB_00133 3.47e-79 ytkL - - S - - - Beta-lactamase superfamily domain
LAPPPGAB_00134 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
LAPPPGAB_00135 6.86e-100 - - - F - - - Phosphorylase superfamily
LAPPPGAB_00136 5.82e-120 - - - L - - - Probable transposase
LAPPPGAB_00137 9.19e-78 - - - L - - - Resolvase, N-terminal domain
LAPPPGAB_00138 1.82e-33 - - - - - - - -
LAPPPGAB_00139 5.54e-139 dkgB - - S - - - reductase
LAPPPGAB_00141 4.52e-27 rimL 1.1.1.25 - J ko:K00014,ko:K03817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LAPPPGAB_00142 2.25e-216 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LAPPPGAB_00143 5.57e-257 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LAPPPGAB_00144 9.63e-72 - - - EGP - - - Transmembrane secretion effector
LAPPPGAB_00145 7.37e-175 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LAPPPGAB_00146 3.44e-66 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LAPPPGAB_00147 6.82e-235 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LAPPPGAB_00149 1.54e-140 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LAPPPGAB_00150 4.48e-158 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPGAB_00151 1.91e-187 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LAPPPGAB_00152 3.94e-249 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LAPPPGAB_00153 1.93e-253 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LAPPPGAB_00154 1.49e-193 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
LAPPPGAB_00155 2.4e-146 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LAPPPGAB_00156 1.26e-62 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LAPPPGAB_00157 1.92e-176 - - - E - - - Beta-eliminating lyase
LAPPPGAB_00158 3.15e-114 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
LAPPPGAB_00159 1.9e-31 veg - - S - - - Biofilm formation stimulator VEG
LAPPPGAB_00160 8.87e-168 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LAPPPGAB_00161 4.87e-112 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LAPPPGAB_00162 2.97e-132 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
LAPPPGAB_00163 1.8e-33 - - - L - - - Transposase
LAPPPGAB_00164 4.44e-41 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
LAPPPGAB_00165 1.67e-123 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LAPPPGAB_00166 1.79e-170 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LAPPPGAB_00167 1.77e-33 yozE - - S - - - Belongs to the UPF0346 family
LAPPPGAB_00168 1.39e-69 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
LAPPPGAB_00169 9.29e-101 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
LAPPPGAB_00171 7.2e-142 ydhF - - S - - - Aldo keto reductase
LAPPPGAB_00172 9.1e-32 - - - K - - - regulatory protein
LAPPPGAB_00173 1.16e-170 - - - C - - - Aldo keto reductase
LAPPPGAB_00174 7.52e-74 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LAPPPGAB_00175 3.9e-200 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LAPPPGAB_00176 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00177 1.45e-167 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LAPPPGAB_00178 1.85e-136 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LAPPPGAB_00179 9.4e-143 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAPPPGAB_00180 2.71e-87 - - - L - - - Phage integrase, N-terminal SAM-like domain
LAPPPGAB_00182 1.87e-75 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
LAPPPGAB_00183 5.93e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LAPPPGAB_00184 2.08e-148 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LAPPPGAB_00187 3.57e-125 - - - M - - - Glycosyltransferase like family 2
LAPPPGAB_00188 1.05e-107 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
LAPPPGAB_00189 1.11e-114 - - - M - - - transferase activity, transferring glycosyl groups
LAPPPGAB_00190 4.35e-160 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAPPPGAB_00191 7.32e-101 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LAPPPGAB_00192 3.11e-108 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LAPPPGAB_00193 5.71e-72 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
LAPPPGAB_00194 4.9e-300 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
LAPPPGAB_00195 9.06e-181 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LAPPPGAB_00196 3.85e-46 ypmB - - S - - - Protein conserved in bacteria
LAPPPGAB_00197 3.58e-269 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LAPPPGAB_00198 5.52e-121 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
LAPPPGAB_00199 1.78e-156 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
LAPPPGAB_00200 2.3e-172 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
LAPPPGAB_00201 3.76e-143 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LAPPPGAB_00202 1.79e-134 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LAPPPGAB_00203 1.76e-186 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LAPPPGAB_00204 1.71e-90 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LAPPPGAB_00205 7.31e-63 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
LAPPPGAB_00206 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LAPPPGAB_00207 4.58e-73 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LAPPPGAB_00208 6.94e-28 - - - - - - - -
LAPPPGAB_00210 7.02e-157 - - - K - - - LysR substrate binding domain
LAPPPGAB_00211 1.38e-242 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LAPPPGAB_00213 7.25e-163 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LAPPPGAB_00214 1.81e-24 - - - - - - - -
LAPPPGAB_00215 3.58e-132 - - - E - - - AzlC protein
LAPPPGAB_00216 2.61e-52 - - - S - - - branched-chain amino acid
LAPPPGAB_00217 3.45e-81 - - - I - - - alpha/beta hydrolase fold
LAPPPGAB_00218 1.65e-24 - - - - - - - -
LAPPPGAB_00219 1.84e-74 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
LAPPPGAB_00220 1.23e-27 - - - - - - - -
LAPPPGAB_00221 1.01e-117 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LAPPPGAB_00222 1.77e-115 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
LAPPPGAB_00223 1.37e-37 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
LAPPPGAB_00224 9.59e-104 - - - S - - - Putative threonine/serine exporter
LAPPPGAB_00225 1.97e-64 - - - S - - - Threonine/Serine exporter, ThrE
LAPPPGAB_00226 1.6e-154 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LAPPPGAB_00227 2.8e-108 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
LAPPPGAB_00228 7.86e-46 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LAPPPGAB_00229 1.09e-28 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LAPPPGAB_00230 4.77e-28 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LAPPPGAB_00231 1.16e-83 - - - S - - - Uncharacterised protein, DegV family COG1307
LAPPPGAB_00233 1.09e-68 ccl - - S - - - QueT transporter
LAPPPGAB_00234 7.29e-46 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
LAPPPGAB_00235 1.22e-128 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LAPPPGAB_00236 1.24e-137 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
LAPPPGAB_00237 3.68e-219 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LAPPPGAB_00238 4.31e-121 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LAPPPGAB_00239 6.76e-112 - - - S - - - Alpha beta hydrolase
LAPPPGAB_00240 1.32e-57 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LAPPPGAB_00241 6.92e-175 - - - V - - - MatE
LAPPPGAB_00242 4.64e-198 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
LAPPPGAB_00243 3.99e-92 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LAPPPGAB_00244 3.23e-125 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LAPPPGAB_00245 1.13e-162 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
LAPPPGAB_00246 4.83e-94 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LAPPPGAB_00247 2.76e-33 - - - - - - - -
LAPPPGAB_00248 6.84e-232 yhdP - - S - - - Transporter associated domain
LAPPPGAB_00249 1.77e-101 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LAPPPGAB_00250 0.0 - - - L - - - Helicase C-terminal domain protein
LAPPPGAB_00251 5.89e-316 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LAPPPGAB_00252 8.72e-269 yhdG - - E ko:K03294 - ko00000 Amino Acid
LAPPPGAB_00253 4.97e-69 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LAPPPGAB_00254 5.33e-17 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
LAPPPGAB_00255 9.05e-123 - - - - - - - -
LAPPPGAB_00256 1.32e-17 - - - - - - - -
LAPPPGAB_00257 6.02e-133 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00258 4.84e-126 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LAPPPGAB_00259 4.89e-111 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LAPPPGAB_00260 1.88e-104 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LAPPPGAB_00261 4.45e-224 eriC - - P ko:K03281 - ko00000 chloride
LAPPPGAB_00262 1.19e-32 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
LAPPPGAB_00263 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LAPPPGAB_00264 4.3e-91 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LAPPPGAB_00265 1.37e-53 - - - - - - - -
LAPPPGAB_00266 1.68e-148 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
LAPPPGAB_00267 1.52e-134 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LAPPPGAB_00268 4.94e-181 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
LAPPPGAB_00269 1.22e-73 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
LAPPPGAB_00270 3.34e-90 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LAPPPGAB_00271 6.05e-146 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
LAPPPGAB_00272 3.92e-92 - - - S - - - Protein of unknown function (DUF1361)
LAPPPGAB_00273 4.8e-163 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LAPPPGAB_00274 4.54e-87 ybbR - - S - - - YbbR-like protein
LAPPPGAB_00275 1.1e-284 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LAPPPGAB_00276 1.59e-38 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LAPPPGAB_00277 1.53e-163 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
LAPPPGAB_00278 1.17e-23 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
LAPPPGAB_00279 3.47e-250 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LAPPPGAB_00280 1.61e-207 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LAPPPGAB_00281 2.52e-122 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
LAPPPGAB_00282 3.05e-110 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LAPPPGAB_00283 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LAPPPGAB_00284 4.21e-136 ymfF - - S - - - Peptidase M16 inactive domain protein
LAPPPGAB_00285 1.82e-186 ymfH - - S - - - Peptidase M16
LAPPPGAB_00286 5.2e-116 ymfI 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LAPPPGAB_00287 7.25e-85 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
LAPPPGAB_00288 5.99e-111 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LAPPPGAB_00289 1.84e-203 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LAPPPGAB_00290 4.38e-256 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LAPPPGAB_00291 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LAPPPGAB_00292 2.45e-288 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LAPPPGAB_00293 2.19e-91 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LAPPPGAB_00294 1.45e-193 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LAPPPGAB_00295 2.88e-231 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LAPPPGAB_00296 1.64e-260 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LAPPPGAB_00297 1.06e-20 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
LAPPPGAB_00299 2.26e-130 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_00303 7.98e-21 ftsK - - D ko:K03466 - ko00000,ko03036 FtsK SpoIIIE family protein
LAPPPGAB_00306 2.65e-43 lytE - - M - - - Lysin motif
LAPPPGAB_00308 9.64e-24 - - - - - - - -
LAPPPGAB_00311 7.31e-91 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
LAPPPGAB_00314 6.96e-58 - - - L - - - PFAM HNH endonuclease
LAPPPGAB_00317 1.91e-153 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 DnaB-like helicase C terminal domain
LAPPPGAB_00318 2.13e-40 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
LAPPPGAB_00319 1.84e-86 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
LAPPPGAB_00321 6.11e-46 - - - L ko:K07496 - ko00000 Helix-turn-helix domain
LAPPPGAB_00323 4.74e-57 - - - L - - - DNA restriction-modification system
LAPPPGAB_00330 1.54e-17 - - - - - - - -
LAPPPGAB_00339 1.75e-53 - - - M - - - Prophage endopeptidase tail
LAPPPGAB_00348 7.31e-44 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LAPPPGAB_00353 9.94e-54 - - - T - - - phosphatase
LAPPPGAB_00356 1.55e-49 - - - - - - - -
LAPPPGAB_00364 1e-166 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LAPPPGAB_00367 6.4e-126 - - - O - - - ATPase family associated with various cellular activities (AAA)
LAPPPGAB_00373 1.13e-65 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
LAPPPGAB_00375 3.24e-38 - - - - - - - -
LAPPPGAB_00383 3.07e-24 - - - S - - - protein disulfide oxidoreductase activity
LAPPPGAB_00387 4.74e-75 - - - S - - - Phage tail assembly chaperone proteins, TAC
LAPPPGAB_00388 6.32e-158 - - - S - - - Phage tail tube protein
LAPPPGAB_00389 7.23e-85 - - - S - - - Protein of unknown function (DUF806)
LAPPPGAB_00390 2.78e-85 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LAPPPGAB_00391 2.69e-79 - - - S - - - Phage head-tail joining protein
LAPPPGAB_00392 3.09e-29 - - - S - - - Phage gp6-like head-tail connector protein
LAPPPGAB_00393 2.24e-281 - - - S - - - Phage capsid family
LAPPPGAB_00394 2.97e-152 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
LAPPPGAB_00395 1.41e-263 - - - S - - - Phage portal protein
LAPPPGAB_00397 0.0 - - - S - - - Phage Terminase
LAPPPGAB_00398 1.05e-107 - - - L - - - Phage terminase, small subunit
LAPPPGAB_00399 2.55e-114 - - - L - - - HNH nucleases
LAPPPGAB_00400 1.89e-29 - - - - - - - -
LAPPPGAB_00403 1.13e-36 - - - S - - - Phage transcriptional regulator, ArpU family
LAPPPGAB_00416 5.38e-46 - - - L - - - recombinase activity
LAPPPGAB_00419 4.95e-90 - - - - - - - -
LAPPPGAB_00420 4.18e-28 - - - - - - - -
LAPPPGAB_00423 1.81e-26 - - - S - - - N-terminal phage replisome organiser (Phage_rep_org_N)
LAPPPGAB_00424 9.24e-68 - - - S - - - Putative HNHc nuclease
LAPPPGAB_00429 3.66e-25 - - - S - - - Domain of unknown function (DUF771)
LAPPPGAB_00430 2.63e-12 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
LAPPPGAB_00431 5.79e-48 - - - K - - - Helix-turn-helix XRE-family like proteins
LAPPPGAB_00432 3.98e-50 - - - E - - - Zn peptidase
LAPPPGAB_00434 2.74e-36 - - - S - - - Short C-terminal domain
LAPPPGAB_00435 4.43e-23 - - - L - - - nuclease
LAPPPGAB_00436 9.01e-18 - - - - - - - -
LAPPPGAB_00437 1.65e-28 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
LAPPPGAB_00439 1.22e-20 - - - - - - - -
LAPPPGAB_00440 5.42e-146 int3 - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_00441 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LAPPPGAB_00442 3.68e-55 - - - S - - - repeat protein
LAPPPGAB_00443 4.85e-128 pgm - - G - - - Phosphoglycerate mutase family
LAPPPGAB_00444 3.01e-57 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
LAPPPGAB_00445 1.18e-116 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
LAPPPGAB_00446 7.75e-256 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
LAPPPGAB_00448 7.08e-105 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LAPPPGAB_00449 1.13e-68 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
LAPPPGAB_00450 3.04e-159 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
LAPPPGAB_00451 3.75e-200 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
LAPPPGAB_00452 0.0 ydaO - - E - - - amino acid
LAPPPGAB_00453 0.0 - - - P ko:K12952 - ko00000,ko01000 COG COG0474 Cation transport ATPase
LAPPPGAB_00454 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LAPPPGAB_00455 1.7e-46 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LAPPPGAB_00456 1.43e-41 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LAPPPGAB_00457 1.52e-126 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LAPPPGAB_00458 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
LAPPPGAB_00459 2.51e-206 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LAPPPGAB_00460 1.9e-19 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LAPPPGAB_00461 5.25e-88 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
LAPPPGAB_00462 1.15e-177 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
LAPPPGAB_00463 6.03e-105 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
LAPPPGAB_00464 9.92e-121 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LAPPPGAB_00465 3.85e-52 yabA - - L - - - Involved in initiation control of chromosome replication
LAPPPGAB_00466 1.32e-104 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LAPPPGAB_00467 2.18e-83 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LAPPPGAB_00468 4.16e-39 yaaL - - S - - - Protein of unknown function (DUF2508)
LAPPPGAB_00469 6.62e-126 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LAPPPGAB_00470 3.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LAPPPGAB_00471 2.21e-267 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LAPPPGAB_00472 2.23e-80 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LAPPPGAB_00473 4.53e-96 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LAPPPGAB_00474 3.91e-37 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
LAPPPGAB_00475 2.21e-59 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
LAPPPGAB_00476 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAPPPGAB_00477 1.1e-203 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LAPPPGAB_00478 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LAPPPGAB_00479 7.33e-71 - - - - - - - -
LAPPPGAB_00480 2.18e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LAPPPGAB_00481 2.21e-97 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LAPPPGAB_00482 9.98e-150 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LAPPPGAB_00483 2.58e-88 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LAPPPGAB_00484 3.13e-109 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LAPPPGAB_00485 3.08e-16 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LAPPPGAB_00486 3.3e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LAPPPGAB_00487 1.33e-53 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LAPPPGAB_00488 4.1e-109 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LAPPPGAB_00489 2.13e-163 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LAPPPGAB_00490 2.66e-148 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LAPPPGAB_00492 9.77e-56 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LAPPPGAB_00493 5.71e-317 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
LAPPPGAB_00494 2.65e-165 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LAPPPGAB_00495 3.1e-307 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LAPPPGAB_00496 3.32e-113 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LAPPPGAB_00497 9.25e-124 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
LAPPPGAB_00498 1.5e-115 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LAPPPGAB_00501 4.29e-260 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
LAPPPGAB_00503 3.23e-262 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LAPPPGAB_00504 7.55e-308 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
LAPPPGAB_00505 7.88e-87 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LAPPPGAB_00506 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LAPPPGAB_00507 4.07e-14 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LAPPPGAB_00508 5.31e-72 lssY 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
LAPPPGAB_00509 2.71e-106 lysR5 - - K - - - LysR substrate binding domain
LAPPPGAB_00510 3.86e-154 - - - S ko:K07090 - ko00000 membrane transporter protein
LAPPPGAB_00511 1.39e-42 - - - S - - - Protein of unknown function (DUF1634)
LAPPPGAB_00512 6.86e-159 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LAPPPGAB_00513 7.34e-285 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LAPPPGAB_00514 8.04e-21 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LAPPPGAB_00515 8.31e-208 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
LAPPPGAB_00516 6.81e-103 - - - S - - - L,D-transpeptidase catalytic domain
LAPPPGAB_00517 3.67e-172 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LAPPPGAB_00518 2.47e-185 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LAPPPGAB_00519 1.86e-35 yuxO - - Q - - - Thioesterase superfamily
LAPPPGAB_00520 1.68e-69 - - - F - - - Glutamine amidotransferase class-I
LAPPPGAB_00521 2.05e-189 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
LAPPPGAB_00522 2.47e-146 degV - - S - - - EDD domain protein, DegV family
LAPPPGAB_00523 3.6e-293 cadA - - P - - - P-type ATPase
LAPPPGAB_00524 0.0 - - - E - - - Amino acid permease
LAPPPGAB_00525 2.22e-108 - - - S - - - Membrane
LAPPPGAB_00526 3.27e-57 cps3F - - - - - - -
LAPPPGAB_00527 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
LAPPPGAB_00528 4.7e-192 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LAPPPGAB_00529 1.2e-112 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
LAPPPGAB_00530 5.37e-279 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
LAPPPGAB_00531 3.81e-37 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
LAPPPGAB_00532 2.52e-17 - - - - - - - -
LAPPPGAB_00533 1.57e-77 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LAPPPGAB_00534 2.36e-72 - - - S - - - Protein of unknown function (DUF975)
LAPPPGAB_00535 9.52e-187 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LAPPPGAB_00536 8.8e-291 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
LAPPPGAB_00537 7.39e-228 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LAPPPGAB_00538 6.13e-212 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
LAPPPGAB_00539 1.49e-223 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
LAPPPGAB_00542 9.21e-45 - - - S - - - Protein of unknown function (DUF4256)
LAPPPGAB_00543 3.63e-163 metQ - - M ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LAPPPGAB_00544 1.02e-73 metI - - U ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LAPPPGAB_00545 1.53e-192 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LAPPPGAB_00547 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
LAPPPGAB_00548 1.29e-215 npr 1.11.1.1 - S ko:K05910 - ko00000,ko01000 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LAPPPGAB_00549 2.34e-136 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
LAPPPGAB_00550 4.37e-106 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
LAPPPGAB_00551 2.84e-107 - - - C - - - nitroreductase
LAPPPGAB_00552 3.22e-168 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
LAPPPGAB_00553 7.43e-119 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LAPPPGAB_00554 1.87e-188 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LAPPPGAB_00555 4.23e-135 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LAPPPGAB_00556 1.03e-176 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
LAPPPGAB_00557 5.1e-60 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
LAPPPGAB_00558 6.56e-73 yphH - - S - - - Cupin domain
LAPPPGAB_00559 6.01e-60 - - - C - - - Flavodoxin
LAPPPGAB_00560 4.1e-70 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LAPPPGAB_00561 2.22e-131 pgm3 - - G - - - phosphoglycerate mutase
LAPPPGAB_00562 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LAPPPGAB_00563 6.13e-286 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LAPPPGAB_00564 6.58e-70 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LAPPPGAB_00565 8.27e-86 yciB - - M - - - ErfK YbiS YcfS YnhG
LAPPPGAB_00566 1.41e-138 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00567 9.74e-147 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LAPPPGAB_00568 2.26e-168 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
LAPPPGAB_00569 2.79e-200 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LAPPPGAB_00570 1.26e-132 potC - - U ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LAPPPGAB_00571 3.16e-152 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
LAPPPGAB_00572 8.99e-212 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LAPPPGAB_00573 3.27e-130 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LAPPPGAB_00574 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
LAPPPGAB_00575 1.18e-295 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LAPPPGAB_00577 8.46e-23 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LAPPPGAB_00578 3.71e-09 - - - S - - - Putative adhesin
LAPPPGAB_00579 2.43e-25 - - - S - - - Protein of unknown function (DUF1700)
LAPPPGAB_00580 1.03e-50 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
LAPPPGAB_00581 3.61e-43 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LAPPPGAB_00582 1.36e-96 ung2 - - L - - - Uracil-DNA glycosylase
LAPPPGAB_00583 1.19e-208 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPGAB_00584 4.1e-164 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LAPPPGAB_00585 4.25e-92 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
LAPPPGAB_00586 7.96e-68 - - - S - - - Domain of unknown function (DUF956)
LAPPPGAB_00587 1.4e-188 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LAPPPGAB_00588 1.69e-153 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
LAPPPGAB_00589 3.19e-192 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LAPPPGAB_00590 3.08e-101 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 sugar-binding domain protein
LAPPPGAB_00591 2.16e-120 baeS - - T - - - Histidine kinase
LAPPPGAB_00592 1.51e-101 yfiK - - K ko:K02479 - ko00000,ko02022 Bacterial regulatory proteins, luxR family
LAPPPGAB_00593 5.94e-148 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LAPPPGAB_00594 1.22e-89 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LAPPPGAB_00595 9.06e-52 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LAPPPGAB_00596 1.24e-43 - - - K - - - MerR HTH family regulatory protein
LAPPPGAB_00597 1.41e-246 ycnB - - U - - - Belongs to the major facilitator superfamily
LAPPPGAB_00598 2.82e-42 - - - S - - - Domain of unknown function (DUF4811)
LAPPPGAB_00599 2.88e-50 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
LAPPPGAB_00600 4.71e-76 yceE - - S - - - haloacid dehalogenase-like hydrolase
LAPPPGAB_00601 5.62e-92 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LAPPPGAB_00602 2.69e-116 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LAPPPGAB_00603 2.6e-230 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
LAPPPGAB_00604 5.42e-71 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LAPPPGAB_00605 4.53e-112 - - - S - - - Predicted membrane protein (DUF2207)
LAPPPGAB_00606 4.02e-28 - - - - - - - -
LAPPPGAB_00607 3.37e-16 epsJ2 - - S - - - Glycosyltransferase like family 2
LAPPPGAB_00608 7.12e-68 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
LAPPPGAB_00609 1.53e-74 - - - P ko:K03499 - ko00000,ko02000 TrkA-N domain
LAPPPGAB_00610 1.2e-144 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
LAPPPGAB_00611 1.37e-229 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LAPPPGAB_00612 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LAPPPGAB_00613 5.21e-269 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LAPPPGAB_00614 9.33e-186 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LAPPPGAB_00616 3.01e-117 - - - M - - - Prophage endopeptidase tail
LAPPPGAB_00618 4.17e-113 - - - L - - - Phage tail tape measure protein TP901
LAPPPGAB_00619 3.88e-50 - - - S - - - Bacteriophage Gp15 protein
LAPPPGAB_00621 1.35e-49 - - - N - - - domain, Protein
LAPPPGAB_00624 1.86e-39 - - - S - - - Minor capsid protein
LAPPPGAB_00626 2.49e-123 - - - S - - - T=7 icosahedral viral capsid
LAPPPGAB_00627 3.67e-29 - - - S - - - Phage minor structural protein GP20
LAPPPGAB_00629 2.21e-116 - - - S - - - Phage minor capsid protein 2
LAPPPGAB_00630 2.69e-177 - - - S - - - Phage portal protein, SPP1 Gp6-like
LAPPPGAB_00631 1.12e-208 - - - S ko:K06909 - ko00000 Terminase RNAseH like domain
LAPPPGAB_00632 1.83e-43 - - - - - - - -
LAPPPGAB_00639 2.99e-65 - - - S - - - VRR_NUC
LAPPPGAB_00640 1.05e-291 - - - S ko:K06919 - ko00000 Virulence-associated protein E
LAPPPGAB_00641 1.28e-180 - - - S - - - Bifunctional DNA primase/polymerase, N-terminal
LAPPPGAB_00642 2.84e-109 - - - - - - - -
LAPPPGAB_00643 1.26e-148 - - - L - - - AAA domain
LAPPPGAB_00644 2.78e-308 - - - L - - - Helicase C-terminal domain protein
LAPPPGAB_00645 6.29e-100 - - - S - - - Siphovirus Gp157
LAPPPGAB_00649 7.85e-20 - - - K - - - Cro/C1-type HTH DNA-binding domain
LAPPPGAB_00650 3.98e-41 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LAPPPGAB_00651 2.39e-26 - - - - - - - -
LAPPPGAB_00654 1.24e-150 - - - K - - - Transcriptional regulator
LAPPPGAB_00655 1.15e-08 ansR - - K - - - transcriptional
LAPPPGAB_00657 5.38e-23 - - - K - - - transcriptional
LAPPPGAB_00659 7.56e-28 - - - - - - - -
LAPPPGAB_00660 2.94e-99 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_00661 7.31e-164 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LAPPPGAB_00662 2e-171 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LAPPPGAB_00663 6.9e-37 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
LAPPPGAB_00664 4.86e-120 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
LAPPPGAB_00665 3.48e-114 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
LAPPPGAB_00666 2.55e-65 yugI - - J ko:K07570 - ko00000 general stress protein
LAPPPGAB_00667 1.63e-118 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LAPPPGAB_00668 1.08e-117 dedA - - S ko:K03975 - ko00000 SNARE associated Golgi protein
LAPPPGAB_00669 4.04e-39 - - - S - - - Protein of unknown function (DUF1461)
LAPPPGAB_00670 1.19e-145 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LAPPPGAB_00671 4.29e-77 yutD - - S - - - Protein of unknown function (DUF1027)
LAPPPGAB_00672 4.57e-73 - - - S - - - Calcineurin-like phosphoesterase
LAPPPGAB_00673 2.02e-237 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LAPPPGAB_00674 3.26e-122 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LAPPPGAB_00678 7.13e-18 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
LAPPPGAB_00679 8.75e-36 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
LAPPPGAB_00680 5.94e-124 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
LAPPPGAB_00681 3.19e-152 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
LAPPPGAB_00682 4.7e-129 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LAPPPGAB_00683 2.31e-152 yebC - - K - - - Transcriptional regulatory protein
LAPPPGAB_00684 4.81e-54 - - - S - - - VanZ like family
LAPPPGAB_00685 1.26e-202 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LAPPPGAB_00686 7.52e-218 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LAPPPGAB_00688 1.22e-09 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LAPPPGAB_00690 3.43e-96 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LAPPPGAB_00691 3.39e-47 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LAPPPGAB_00692 5.92e-83 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
LAPPPGAB_00693 1.13e-52 - - - K - - - Domain of unknown function (DUF1836)
LAPPPGAB_00694 2.71e-107 - - - S - - - membrane
LAPPPGAB_00695 1.39e-100 - - - S - - - VIT family
LAPPPGAB_00696 1.21e-188 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
LAPPPGAB_00697 2.26e-73 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
LAPPPGAB_00698 6.43e-149 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LAPPPGAB_00699 2.14e-146 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LAPPPGAB_00700 1.35e-154 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
LAPPPGAB_00701 5.19e-150 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LAPPPGAB_00702 4.34e-125 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LAPPPGAB_00703 1.3e-53 yjbH - - Q - - - Thioredoxin
LAPPPGAB_00704 2.04e-287 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LAPPPGAB_00705 1.21e-83 coiA - - S ko:K06198 - ko00000 Competence protein
LAPPPGAB_00706 1.08e-61 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LAPPPGAB_00707 1.78e-273 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
LAPPPGAB_00720 2.08e-88 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
LAPPPGAB_00721 6.4e-80 phaJ - - I - - - N-terminal half of MaoC dehydratase
LAPPPGAB_00722 1.01e-281 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LAPPPGAB_00723 6.26e-294 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LAPPPGAB_00724 1.75e-97 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LAPPPGAB_00725 2.95e-59 ytpP - - CO - - - Thioredoxin
LAPPPGAB_00726 4.74e-130 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LAPPPGAB_00727 3.39e-125 ytmP - - M - - - Choline/ethanolamine kinase
LAPPPGAB_00728 5.63e-88 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LAPPPGAB_00729 9.47e-121 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00730 1.1e-68 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
LAPPPGAB_00732 7.01e-144 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LAPPPGAB_00733 8.86e-161 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
LAPPPGAB_00734 7.2e-29 yheA - - S - - - Belongs to the UPF0342 family
LAPPPGAB_00735 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LAPPPGAB_00736 7.46e-148 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_00737 9.66e-17 ansR - - K - - - Transcriptional regulator
LAPPPGAB_00739 4.04e-36 - - - K - - - COG3617 Prophage antirepressor
LAPPPGAB_00744 3.65e-26 - - - - - - - -
LAPPPGAB_00746 1.45e-41 - - - L - - - DnaD domain protein
LAPPPGAB_00749 3.73e-11 - - - - - - - -
LAPPPGAB_00753 2.28e-115 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
LAPPPGAB_00754 4.06e-224 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LAPPPGAB_00755 2.43e-92 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LAPPPGAB_00756 2.26e-59 ykuL - - S - - - CBS domain
LAPPPGAB_00757 2.12e-152 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
LAPPPGAB_00758 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LAPPPGAB_00759 2.1e-305 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LAPPPGAB_00760 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LAPPPGAB_00761 1.85e-161 - - - - - - - -
LAPPPGAB_00762 7.19e-189 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
LAPPPGAB_00763 5.94e-54 - - - ET - - - Bacterial extracellular solute-binding proteins, family 3
LAPPPGAB_00764 5.39e-40 - - - K - - - Bacterial regulatory proteins, tetR family
LAPPPGAB_00765 9.06e-131 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LAPPPGAB_00766 1.19e-105 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LAPPPGAB_00767 1.6e-128 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
LAPPPGAB_00768 2.31e-216 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LAPPPGAB_00769 2.75e-160 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LAPPPGAB_00770 0.0 - - - L - - - DNA helicase
LAPPPGAB_00772 1.77e-155 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LAPPPGAB_00773 2.31e-94 lemA - - S ko:K03744 - ko00000 LemA family
LAPPPGAB_00774 1.2e-67 ymdB - - L - - - phosphatase homologous to the C-terminal domain of histone macroH2A1
LAPPPGAB_00775 5.29e-59 yyaT - - K ko:K02348 - ko00000 protein acetylation
LAPPPGAB_00776 1.29e-11 - - - - - - - -
LAPPPGAB_00777 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
LAPPPGAB_00778 7.59e-279 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00779 6.28e-44 - - - K - - - Bacterial regulatory proteins, tetR family
LAPPPGAB_00780 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00781 1.1e-277 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LAPPPGAB_00782 2.38e-189 - - - G - - - Transporter, major facilitator family protein
LAPPPGAB_00783 5.54e-111 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LAPPPGAB_00784 5.29e-191 hpk31 - - T - - - Histidine kinase
LAPPPGAB_00785 1.21e-145 vanR - - K - - - response regulator
LAPPPGAB_00786 7.86e-106 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LAPPPGAB_00787 4.67e-117 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LAPPPGAB_00788 1.8e-33 - - - L - - - Transposase
LAPPPGAB_00789 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
LAPPPGAB_00790 2.55e-91 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
LAPPPGAB_00791 6.73e-161 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
LAPPPGAB_00792 3.62e-130 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
LAPPPGAB_00793 4.07e-102 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LAPPPGAB_00794 4.97e-153 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
LAPPPGAB_00795 4.14e-138 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LAPPPGAB_00796 3.11e-33 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
LAPPPGAB_00797 2.94e-242 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LAPPPGAB_00798 7.75e-74 - - - S - - - Protein of unknown function (DUF1129)
LAPPPGAB_00799 7.12e-19 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
LAPPPGAB_00800 7.67e-46 - - - - - - - -
LAPPPGAB_00801 1.63e-70 - - - V - - - Abi-like protein
LAPPPGAB_00802 5.14e-132 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LAPPPGAB_00803 1.13e-126 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LAPPPGAB_00804 3.47e-138 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
LAPPPGAB_00805 3.99e-71 - - - S - - - ECF transporter, substrate-specific component
LAPPPGAB_00806 2.85e-129 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LAPPPGAB_00807 2.19e-113 - - - S - - - NADPH-dependent FMN reductase
LAPPPGAB_00808 2.64e-35 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LAPPPGAB_00809 1.47e-85 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LAPPPGAB_00811 4.32e-192 - - - EGP - - - Major Facilitator
LAPPPGAB_00812 9.17e-78 - - - S - - - Haloacid dehalogenase-like hydrolase
LAPPPGAB_00813 1.3e-114 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
LAPPPGAB_00814 4.18e-46 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
LAPPPGAB_00815 1.16e-147 cps3J - - M - - - Domain of unknown function (DUF4422)
LAPPPGAB_00816 4.42e-77 - - - S - - - Glycosyltransferase like family 2
LAPPPGAB_00817 9.89e-172 tetA - - EGP ko:K08151,ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko01504,ko02000 Major facilitator Superfamily
LAPPPGAB_00818 8.77e-44 - - - S - - - MazG nucleotide pyrophosphohydrolase domain
LAPPPGAB_00819 2.25e-267 potE - - E - - - Amino Acid
LAPPPGAB_00820 9.95e-241 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LAPPPGAB_00821 3.21e-142 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00822 5.17e-228 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LAPPPGAB_00823 1.13e-116 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LAPPPGAB_00824 1.79e-148 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LAPPPGAB_00825 5.56e-124 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
LAPPPGAB_00826 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
LAPPPGAB_00827 6.02e-46 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LAPPPGAB_00828 3.15e-254 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
LAPPPGAB_00829 1.37e-96 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LAPPPGAB_00830 2.58e-77 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
LAPPPGAB_00831 5.7e-82 - - - S - - - ECF transporter, substrate-specific component
LAPPPGAB_00832 6.23e-164 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
LAPPPGAB_00833 3.4e-313 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
LAPPPGAB_00834 7.97e-90 mleR - - K - - - LysR family
LAPPPGAB_00835 3.65e-74 napB - - K - - - transcriptional
LAPPPGAB_00836 4.74e-52 - - - K - - - Bacterial regulatory proteins, tetR family
LAPPPGAB_00837 2.3e-78 usp2 - - T - - - Belongs to the universal stress protein A family
LAPPPGAB_00838 2.15e-59 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
LAPPPGAB_00839 1.3e-90 - - - M - - - Rib/alpha-like repeat
LAPPPGAB_00840 1.43e-170 - - - M - - - Rib/alpha-like repeat
LAPPPGAB_00841 1.7e-129 ypuA - - S - - - Protein of unknown function (DUF1002)
LAPPPGAB_00842 1.28e-76 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
LAPPPGAB_00843 4.63e-205 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LAPPPGAB_00844 5.03e-54 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LAPPPGAB_00845 1.8e-267 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LAPPPGAB_00846 2.78e-249 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
LAPPPGAB_00847 4.35e-301 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LAPPPGAB_00848 2.77e-19 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
LAPPPGAB_00849 5.76e-221 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
LAPPPGAB_00850 4.98e-62 - - - L - - - DNA alkylation repair enzyme
LAPPPGAB_00851 1.72e-174 - - - EG - - - EamA-like transporter family
LAPPPGAB_00852 2.75e-190 XK27_05225 - - S - - - Tetratricopeptide repeat protein
LAPPPGAB_00853 3.65e-255 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LAPPPGAB_00854 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LAPPPGAB_00855 1.24e-173 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
LAPPPGAB_00856 9.47e-221 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LAPPPGAB_00857 1.41e-164 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LAPPPGAB_00858 1.72e-104 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LAPPPGAB_00860 1.79e-119 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LAPPPGAB_00861 5.56e-202 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LAPPPGAB_00862 5.49e-54 XK27_04120 - - S - - - Putative amino acid metabolism
LAPPPGAB_00863 5.64e-256 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LAPPPGAB_00864 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LAPPPGAB_00865 6.47e-21 - - - S - - - Protein of unknown function (DUF2929)
LAPPPGAB_00866 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LAPPPGAB_00867 1.7e-211 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LAPPPGAB_00868 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LAPPPGAB_00870 6.49e-53 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LAPPPGAB_00871 1.38e-106 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LAPPPGAB_00872 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LAPPPGAB_00873 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LAPPPGAB_00874 1.95e-119 yycB - - P ko:K03449 - ko00000,ko02000 Major Facilitator Superfamily
LAPPPGAB_00875 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LAPPPGAB_00876 1.85e-206 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LAPPPGAB_00877 1.75e-78 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
LAPPPGAB_00878 7.27e-111 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LAPPPGAB_00879 4.16e-103 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LAPPPGAB_00880 1.02e-10 - - - K ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LAPPPGAB_00881 2.17e-35 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
LAPPPGAB_00882 4.12e-168 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LAPPPGAB_00883 4.11e-143 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LAPPPGAB_00884 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
LAPPPGAB_00885 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LAPPPGAB_00886 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LAPPPGAB_00887 1.23e-107 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LAPPPGAB_00888 5.61e-102 - - - GM - - - NAD dependent epimerase dehydratase family protein
LAPPPGAB_00889 7.15e-161 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LAPPPGAB_00890 9.11e-195 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LAPPPGAB_00891 2.05e-191 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LAPPPGAB_00892 2.07e-128 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LAPPPGAB_00894 2.76e-175 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
LAPPPGAB_00895 1.19e-231 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LAPPPGAB_00896 1.99e-264 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LAPPPGAB_00897 9.95e-165 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LAPPPGAB_00898 4.33e-298 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LAPPPGAB_00899 7.05e-102 spoVK - - O - - - ATPase family associated with various cellular activities (AAA)
LAPPPGAB_00900 3.52e-34 - - - S - - - Domain of unknown function (DUF3841)
LAPPPGAB_00901 6.05e-75 - - - F - - - Cytidine and deoxycytidylate deaminase zinc-binding region
LAPPPGAB_00902 3.2e-191 - 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 UvrD/REP helicase N-terminal domain
LAPPPGAB_00903 5.02e-294 - - - L - - - AAA ATPase domain
LAPPPGAB_00905 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
LAPPPGAB_00906 3.37e-84 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 COG0732 Restriction endonuclease S subunits
LAPPPGAB_00907 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LAPPPGAB_00909 6.36e-155 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
LAPPPGAB_00910 7.79e-268 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LAPPPGAB_00911 5.09e-183 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
LAPPPGAB_00912 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LAPPPGAB_00913 2.07e-294 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LAPPPGAB_00914 1.34e-50 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LAPPPGAB_00915 1.39e-204 camS - - S - - - sex pheromone
LAPPPGAB_00916 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LAPPPGAB_00917 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LAPPPGAB_00918 1.64e-182 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LAPPPGAB_00922 6.62e-196 yngD - - S ko:K07097 - ko00000 DHHA1 domain
LAPPPGAB_00923 1.8e-56 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
LAPPPGAB_00924 4.12e-75 - - - - - - - -
LAPPPGAB_00925 9.64e-54 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LAPPPGAB_00926 2.22e-30 - - - S - - - Cytochrome B5
LAPPPGAB_00928 6.4e-79 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
LAPPPGAB_00929 5.45e-243 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LAPPPGAB_00930 9.74e-126 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LAPPPGAB_00931 2.86e-135 yueF - - S - - - AI-2E family transporter
LAPPPGAB_00932 3.8e-201 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LAPPPGAB_00933 1.59e-145 tagH 3.6.3.40 - GM ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LAPPPGAB_00934 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LAPPPGAB_00935 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 -beta-galactosidase
LAPPPGAB_00936 0.0 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
LAPPPGAB_00937 4.55e-139 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LAPPPGAB_00938 4.34e-225 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LAPPPGAB_00939 1.26e-207 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LAPPPGAB_00940 6.01e-253 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LAPPPGAB_00941 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LAPPPGAB_00942 4.68e-131 - - - G - - - MucBP domain
LAPPPGAB_00943 1.18e-29 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
LAPPPGAB_00945 6.05e-94 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LAPPPGAB_00947 8.86e-84 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LAPPPGAB_00948 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LAPPPGAB_00949 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
LAPPPGAB_00950 2.13e-46 - - - - - - - -
LAPPPGAB_00951 3.93e-180 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LAPPPGAB_00952 2.33e-196 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LAPPPGAB_00953 1.82e-122 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LAPPPGAB_00954 1.15e-198 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LAPPPGAB_00955 4.21e-53 ybjQ - - S - - - Belongs to the UPF0145 family
LAPPPGAB_00957 3.12e-121 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00958 5.09e-56 - - - K - - - Transcriptional regulator, GntR family
LAPPPGAB_00959 6.98e-235 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
LAPPPGAB_00960 1.63e-85 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LAPPPGAB_00961 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LAPPPGAB_00962 3.17e-138 - - - P - - - Integral membrane protein TerC family
LAPPPGAB_00963 3.75e-49 - - - K - - - Transcriptional regulator
LAPPPGAB_00964 6.78e-122 fliY - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LAPPPGAB_00965 7.11e-129 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_00966 3.9e-134 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LAPPPGAB_00968 4.5e-23 - - - V - - - the current gene model (or a revised gene model) may contain a frame shift
LAPPPGAB_00969 2.9e-236 noxE - - S - - - Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
LAPPPGAB_00970 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LAPPPGAB_00971 7.68e-258 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
LAPPPGAB_00972 6.59e-219 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
LAPPPGAB_00973 3.08e-135 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LAPPPGAB_00974 1.7e-66 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
LAPPPGAB_00975 1.4e-88 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
LAPPPGAB_00976 2.16e-192 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
LAPPPGAB_00977 6.92e-143 dhaK2 2.7.1.28, 2.7.1.29, 4.6.1.15 - G ko:K00863 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak1 domain
LAPPPGAB_00978 2.02e-78 XK27_02085 - - K - - - Bacterial regulatory proteins, tetR family
LAPPPGAB_00979 8.29e-264 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LAPPPGAB_00981 5.69e-142 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LAPPPGAB_00982 3.12e-97 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
LAPPPGAB_00983 1.43e-238 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
LAPPPGAB_00984 2.67e-45 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
LAPPPGAB_00985 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
LAPPPGAB_00986 7.04e-149 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LAPPPGAB_00987 3.96e-76 - - - F - - - Nucleoside 2-deoxyribosyltransferase
LAPPPGAB_00988 1.71e-97 azlC - - E - - - branched-chain amino acid
LAPPPGAB_00989 1.46e-42 - - - S - - - Branched-chain amino acid transport protein (AzlD)
LAPPPGAB_00990 2.21e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LAPPPGAB_00991 1.8e-69 jag - - S ko:K06346 - ko00000 R3H domain protein
LAPPPGAB_00992 3.21e-68 - - - K - - - Transcriptional regulator C-terminal region
LAPPPGAB_00993 8.75e-60 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LAPPPGAB_00994 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
LAPPPGAB_00995 3.19e-139 dat 2.6.1.21 - EH ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 PFAM aminotransferase, class IV
LAPPPGAB_00997 8.87e-88 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
LAPPPGAB_00998 5.56e-61 hmpT - - S - - - ECF-type riboflavin transporter, S component
LAPPPGAB_00999 1.3e-52 - - - K - - - Acetyltransferase GNAT Family
LAPPPGAB_01001 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LAPPPGAB_01002 1.65e-122 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_01004 2.53e-130 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
LAPPPGAB_01005 3.9e-85 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter
LAPPPGAB_01006 1.49e-208 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
LAPPPGAB_01007 5.58e-69 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LAPPPGAB_01008 5.09e-60 - - - S - - - Short repeat of unknown function (DUF308)
LAPPPGAB_01009 3.28e-30 - - - K - - - Transcriptional regulator C-terminal region
LAPPPGAB_01010 5.32e-191 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
LAPPPGAB_01012 1.16e-51 - - - K - - - LytTr DNA-binding domain
LAPPPGAB_01013 9.27e-145 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
LAPPPGAB_01014 9.59e-265 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LAPPPGAB_01015 4.15e-20 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
LAPPPGAB_01016 1.2e-197 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LAPPPGAB_01017 2.46e-229 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LAPPPGAB_01018 7.43e-217 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LAPPPGAB_01019 3.98e-189 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LAPPPGAB_01020 3.56e-253 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LAPPPGAB_01021 1.52e-277 yifK - - E ko:K03293 - ko00000 Amino acid permease
LAPPPGAB_01022 6.95e-112 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LAPPPGAB_01023 3.83e-73 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
LAPPPGAB_01024 3.17e-78 pgm3 - - G - - - phosphoglycerate mutase family
LAPPPGAB_01025 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LAPPPGAB_01026 1.02e-26 - - - S - - - Cupredoxin-like domain
LAPPPGAB_01027 1.82e-57 - - - S - - - Cupredoxin-like domain
LAPPPGAB_01028 2.04e-189 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LAPPPGAB_01029 3.37e-230 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
LAPPPGAB_01030 2.01e-146 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
LAPPPGAB_01031 9.75e-30 - - - K - - - transcriptional regulator
LAPPPGAB_01032 4.08e-43 - - - S - - - intracellular protease amidase
LAPPPGAB_01033 3.32e-33 - - - S - - - intracellular protease amidase
LAPPPGAB_01034 9.64e-168 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
LAPPPGAB_01035 1.66e-102 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LAPPPGAB_01036 3.41e-177 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LAPPPGAB_01037 2.59e-217 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
LAPPPGAB_01038 2.56e-203 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LAPPPGAB_01039 2.95e-249 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
LAPPPGAB_01040 1.9e-69 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
LAPPPGAB_01041 3.9e-168 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Cobalamin-independent synthase, Catalytic domain
LAPPPGAB_01042 6.89e-127 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LAPPPGAB_01043 3.14e-104 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
LAPPPGAB_01044 1.01e-11 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LAPPPGAB_01045 3.46e-78 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
LAPPPGAB_01046 1.22e-199 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LAPPPGAB_01048 4.15e-47 - - - S - - - Sulfite exporter TauE/SafE
LAPPPGAB_01049 4.88e-90 - - - K - - - Sugar-specific transcriptional regulator TrmB
LAPPPGAB_01050 5.08e-213 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LAPPPGAB_01051 7.04e-229 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
LAPPPGAB_01052 1.49e-11 - - - E - - - Amino acid permease
LAPPPGAB_01053 1.16e-313 - - - E - - - Amino acid permease
LAPPPGAB_01054 1.29e-109 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
LAPPPGAB_01055 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
LAPPPGAB_01056 9.55e-96 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LAPPPGAB_01057 3.51e-270 - - - G ko:K16211 - ko00000,ko02000 Transporter, major facilitator family protein
LAPPPGAB_01058 1.64e-126 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
LAPPPGAB_01059 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
LAPPPGAB_01062 9.82e-202 yfmL - - L - - - DEAD DEAH box helicase
LAPPPGAB_01063 1.08e-160 mocA - - S - - - Oxidoreductase
LAPPPGAB_01064 1.13e-32 - - - S - - - Domain of unknown function (DUF4828)
LAPPPGAB_01065 9.89e-215 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LAPPPGAB_01066 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LAPPPGAB_01067 7.79e-245 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LAPPPGAB_01068 7.84e-157 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LAPPPGAB_01069 1.08e-117 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LAPPPGAB_01070 1.33e-182 XK27_08315 - - M - - - Sulfatase
LAPPPGAB_01071 2.8e-221 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
LAPPPGAB_01072 6.02e-161 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LAPPPGAB_01073 5.93e-213 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LAPPPGAB_01074 9.34e-113 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LAPPPGAB_01075 8.04e-220 - - - M - - - Choline/ethanolamine kinase
LAPPPGAB_01076 4.36e-109 - - - M - - - Nucleotidyl transferase
LAPPPGAB_01077 2.24e-198 - - - M - - - Belongs to the BCCT transporter (TC 2.A.15) family
LAPPPGAB_01078 5.78e-67 - - - S - - - peptidoglycan catabolic process
LAPPPGAB_01080 7.7e-213 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LAPPPGAB_01081 3.24e-315 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
LAPPPGAB_01082 3.39e-108 treR - - K ko:K03486 - ko00000,ko03000 UTRA
LAPPPGAB_01083 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LAPPPGAB_01084 1.61e-81 pgm1 - - G - - - phosphoglycerate mutase
LAPPPGAB_01085 5.94e-107 pncA - - Q - - - isochorismatase
LAPPPGAB_01086 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LAPPPGAB_01087 1.71e-131 gntR - - K - - - UbiC transcription regulator-associated domain protein
LAPPPGAB_01088 1.11e-217 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LAPPPGAB_01089 1.11e-35 hxlR - - K - - - Transcriptional regulator, HxlR family
LAPPPGAB_01091 5.84e-182 pbuO_1 - - S ko:K06901 - ko00000,ko02000 Permease family
LAPPPGAB_01092 1.13e-17 - - - T - - - diguanylate cyclase
LAPPPGAB_01093 9.17e-162 ydaJ - - G - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LAPPPGAB_01094 1.33e-237 - - - - - - - -
LAPPPGAB_01095 1.48e-256 - - - S - - - Protein conserved in bacteria
LAPPPGAB_01096 1.21e-255 ydaM - - M - - - Glycosyl transferase family group 2
LAPPPGAB_01097 0.0 - - - S - - - Bacterial cellulose synthase subunit
LAPPPGAB_01098 4.61e-153 - - - T - - - diguanylate cyclase activity
LAPPPGAB_01099 6.61e-36 - - - T - - - Putative diguanylate phosphodiesterase
LAPPPGAB_01100 3.14e-50 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LAPPPGAB_01102 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
LAPPPGAB_01103 2.74e-69 - - - S - - - Membrane
LAPPPGAB_01104 5.92e-80 - - - K - - - helix_turn_helix, arabinose operon control protein
LAPPPGAB_01106 3.21e-266 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
LAPPPGAB_01107 5.92e-33 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
LAPPPGAB_01108 4e-240 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LAPPPGAB_01109 2.25e-77 yokL3 - - J - - - Acetyltransferase (GNAT) domain
LAPPPGAB_01110 7.12e-144 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
LAPPPGAB_01111 7.9e-106 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LAPPPGAB_01112 4.12e-82 - - - - - - - -
LAPPPGAB_01113 3.4e-225 rsmF - - J - - - NOL1 NOP2 sun family protein
LAPPPGAB_01114 8.24e-53 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LAPPPGAB_01116 3.01e-225 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LAPPPGAB_01117 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LAPPPGAB_01118 6.58e-245 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
LAPPPGAB_01119 9.88e-244 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LAPPPGAB_01120 1.04e-79 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LAPPPGAB_01121 8.94e-104 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LAPPPGAB_01122 2.17e-242 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
LAPPPGAB_01123 3.18e-224 - - - S - - - Protein of unknown function DUF262
LAPPPGAB_01125 5.97e-49 - - - - - - - -
LAPPPGAB_01126 9.26e-87 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LAPPPGAB_01127 1.29e-79 - - - K - - - Transcriptional regulator, MarR family
LAPPPGAB_01128 6.05e-129 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LAPPPGAB_01129 1.48e-36 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAPPPGAB_01130 3.45e-130 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
LAPPPGAB_01131 2.21e-125 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LAPPPGAB_01132 4.97e-248 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LAPPPGAB_01133 9.49e-60 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LAPPPGAB_01134 7.97e-85 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LAPPPGAB_01135 5.08e-275 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
LAPPPGAB_01136 1.9e-159 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LAPPPGAB_01137 1.73e-129 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
LAPPPGAB_01138 1.48e-139 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LAPPPGAB_01139 1.89e-291 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LAPPPGAB_01140 1.8e-33 - - - L - - - Transposase
LAPPPGAB_01141 4.55e-20 - - - - - - - -
LAPPPGAB_01142 1e-120 - - - S - - - Psort location CytoplasmicMembrane, score
LAPPPGAB_01143 7.22e-197 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
LAPPPGAB_01144 1.23e-85 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LAPPPGAB_01145 9.29e-120 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LAPPPGAB_01146 9.26e-205 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LAPPPGAB_01147 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LAPPPGAB_01149 1.48e-193 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
LAPPPGAB_01150 3.9e-60 - - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase, family 2
LAPPPGAB_01151 1.66e-248 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
LAPPPGAB_01152 7.47e-42 - - - S - - - Acyltransferase family
LAPPPGAB_01153 2.11e-52 - - - S - - - Peptidase_C39 like family
LAPPPGAB_01154 5.77e-79 - - - M - - - Glycosyltransferase like family 2
LAPPPGAB_01155 6.52e-94 licD1 - - M ko:K07271 - ko00000,ko01000 LicD family
LAPPPGAB_01156 3.58e-68 - - - - - - - -
LAPPPGAB_01157 6.71e-116 - - - M - - - transferase activity, transferring glycosyl groups
LAPPPGAB_01158 4.4e-84 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
LAPPPGAB_01159 1.2e-115 - - - M - - - Core-2/I-Branching enzyme
LAPPPGAB_01160 3.4e-47 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LAPPPGAB_01161 1.03e-85 - - - D - - - Peptidase family M23
LAPPPGAB_01162 1.33e-53 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LAPPPGAB_01163 2.03e-77 - - - T - - - Universal stress protein family
LAPPPGAB_01164 0.0 clpL - - O ko:K04086 - ko00000,ko03110 C-terminal, D2-small domain, of ClpB protein
LAPPPGAB_01165 2.65e-35 - - - - - - - -
LAPPPGAB_01166 5.34e-252 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
LAPPPGAB_01167 3.54e-140 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
LAPPPGAB_01168 8.42e-106 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LAPPPGAB_01169 1.38e-190 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
LAPPPGAB_01170 2.66e-185 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
LAPPPGAB_01171 1.35e-19 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
LAPPPGAB_01172 6e-08 - - - M - - - Glycosyltransferase group 2 family protein
LAPPPGAB_01173 2.15e-36 cpsJ - - M - - - Glycosyltransferase group 2 family protein
LAPPPGAB_01174 1.12e-85 nss - - M - - - transferase activity, transferring glycosyl groups
LAPPPGAB_01175 1.44e-41 - - - M - - - family 8
LAPPPGAB_01176 6.08e-65 - - - M - - - transferase activity, transferring glycosyl groups
LAPPPGAB_01178 6.11e-22 arbY - - M - - - family 8
LAPPPGAB_01179 2.72e-08 - - - M - - - Psort location Cytoplasmic, score 8.87
LAPPPGAB_01180 2.57e-77 nss - - M - - - transferase activity, transferring glycosyl groups
LAPPPGAB_01181 9.26e-134 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LAPPPGAB_01182 9.19e-39 - - - S - - - Glycosyltransferase like family 2
LAPPPGAB_01183 3.86e-188 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LAPPPGAB_01185 4.53e-07 - - - L - - - hmm pf01527
LAPPPGAB_01187 1.04e-100 - - - L ko:K07497 - ko00000 hmm pf00665
LAPPPGAB_01188 3.32e-64 - - - S - - - VIT family
LAPPPGAB_01189 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
LAPPPGAB_01190 5.49e-175 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LAPPPGAB_01191 3.73e-142 rssA - - S - - - Phospholipase, patatin family
LAPPPGAB_01192 3.76e-18 - - - - - - - -
LAPPPGAB_01194 9.98e-45 - - - - - - - -
LAPPPGAB_01195 2.62e-233 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
LAPPPGAB_01199 3.78e-110 - - - S - - - Fic/DOC family
LAPPPGAB_01200 6.58e-11 - - - S - - - protein disulfide oxidoreductase activity
LAPPPGAB_01201 2.65e-14 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Peptidase S24-like
LAPPPGAB_01212 0.000288 - - - - - - - -
LAPPPGAB_01221 1.49e-11 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
LAPPPGAB_01223 1.07e-07 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
LAPPPGAB_01237 1.65e-34 - - - E - - - Zn peptidase
LAPPPGAB_01239 4.92e-189 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LAPPPGAB_01240 1.77e-57 - - - L - - - Lactococcus lactis RepB C-terminus
LAPPPGAB_01247 6.14e-30 - - - - - - - -
LAPPPGAB_01248 1.53e-26 - - - S ko:K07065 - ko00000 Toxic component of a toxin-antitoxin (TA) module. An RNase
LAPPPGAB_01252 3.88e-70 - - - V - - - Type I restriction modification DNA specificity domain
LAPPPGAB_01254 3.19e-40 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
LAPPPGAB_01255 1.21e-195 - 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
LAPPPGAB_01256 1.86e-76 bcgIB 2.1.1.72, 3.1.21.3 - V ko:K01154,ko:K03427 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain
LAPPPGAB_01258 7.05e-21 - - - D - - - nuclear chromosome segregation
LAPPPGAB_01271 4.84e-104 - - - M - - - Gram-positive pilin backbone subunit 2, Cna-B-like domain
LAPPPGAB_01272 2.15e-28 srtB 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
LAPPPGAB_01275 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LAPPPGAB_01276 1.39e-106 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LAPPPGAB_01277 2.95e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LAPPPGAB_01278 4.06e-30 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
LAPPPGAB_01279 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LAPPPGAB_01280 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LAPPPGAB_01281 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LAPPPGAB_01282 6.91e-73 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LAPPPGAB_01284 6.07e-152 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LAPPPGAB_01285 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
LAPPPGAB_01286 1.12e-198 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LAPPPGAB_01287 1.53e-234 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LAPPPGAB_01288 1.38e-165 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LAPPPGAB_01297 7.48e-76 - - - V - - - endonuclease activity
LAPPPGAB_01300 3.02e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LAPPPGAB_01301 1.55e-37 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
LAPPPGAB_01302 4.7e-57 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LAPPPGAB_01303 1.21e-20 - - - - - - - -
LAPPPGAB_01305 3.17e-88 - - - - - - - -
LAPPPGAB_01306 1.68e-125 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LAPPPGAB_01307 3.66e-224 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
LAPPPGAB_01308 5.15e-155 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
LAPPPGAB_01309 4.03e-102 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LAPPPGAB_01310 3.49e-274 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LAPPPGAB_01311 4.82e-49 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LAPPPGAB_01312 2.77e-75 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LAPPPGAB_01313 1.55e-78 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LAPPPGAB_01314 2.3e-127 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LAPPPGAB_01315 6.23e-76 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LAPPPGAB_01316 1.16e-67 - - - S - - - Protein of unknown function (DUF441)
LAPPPGAB_01317 3.06e-159 yitL - - S ko:K00243 - ko00000 S1 domain
LAPPPGAB_01318 1.39e-142 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
LAPPPGAB_01319 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
LAPPPGAB_01320 1.17e-98 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LAPPPGAB_01321 5.33e-237 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
LAPPPGAB_01322 2.27e-83 ypsA - - S - - - Belongs to the UPF0398 family
LAPPPGAB_01323 1.7e-245 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
LAPPPGAB_01324 5.87e-13 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
LAPPPGAB_01325 4.07e-12 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
LAPPPGAB_01327 1.9e-118 dpnM 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (Adenine-specific)
LAPPPGAB_01328 1.83e-163 - 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
LAPPPGAB_01329 0.0 - - - - - - - -
LAPPPGAB_01330 5.62e-06 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
LAPPPGAB_01331 1.36e-22 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
LAPPPGAB_01332 4.81e-51 - - - - - - - -
LAPPPGAB_01333 4.84e-12 - - - - - - - -
LAPPPGAB_01338 3.4e-93 - - - M - - - GNAT acetyltransferase
LAPPPGAB_01339 1.64e-87 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
LAPPPGAB_01340 8.86e-72 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LAPPPGAB_01341 6.87e-103 - - - F - - - Hydrolase, nudix family
LAPPPGAB_01343 4.22e-87 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LAPPPGAB_01344 6.6e-136 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
LAPPPGAB_01345 4.75e-215 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LAPPPGAB_01346 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LAPPPGAB_01347 1.46e-262 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LAPPPGAB_01348 7.63e-237 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LAPPPGAB_01350 5.63e-110 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LAPPPGAB_01351 3.3e-52 - - - - - - - -
LAPPPGAB_01352 1.29e-150 icaA - - M - - - Glycosyl transferase family group 2
LAPPPGAB_01353 3.42e-59 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
LAPPPGAB_01354 6.24e-277 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LAPPPGAB_01355 3.03e-76 - - - S - - - Helix-turn-helix domain
LAPPPGAB_01356 4.96e-158 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
LAPPPGAB_01357 1.1e-25 - - - M - - - Lysin motif
LAPPPGAB_01358 7.21e-112 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LAPPPGAB_01359 1.71e-105 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
LAPPPGAB_01360 5.08e-197 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
LAPPPGAB_01361 1.7e-88 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LAPPPGAB_01362 8.41e-40 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LAPPPGAB_01363 2.68e-198 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LAPPPGAB_01364 6.69e-115 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LAPPPGAB_01366 5.9e-274 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LAPPPGAB_01367 2.62e-220 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
LAPPPGAB_01368 4.73e-40 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LAPPPGAB_01369 1.16e-191 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LAPPPGAB_01370 7.33e-78 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphatase family
LAPPPGAB_01371 3.19e-220 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LAPPPGAB_01372 8.22e-289 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LAPPPGAB_01373 2.02e-48 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LAPPPGAB_01375 2.2e-25 - - - K - - - Psort location Cytoplasmic, score
LAPPPGAB_01376 5.98e-143 natA - - S ko:K01990 - ko00000,ko00002,ko02000 Domain of unknown function (DUF4162)
LAPPPGAB_01377 2.42e-102 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-type Na efflux pump, permease component
LAPPPGAB_01378 2.95e-121 - - - EG - - - EamA-like transporter family
LAPPPGAB_01379 8.71e-100 - - - S - - - Calcineurin-like phosphoesterase
LAPPPGAB_01380 1.85e-236 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LAPPPGAB_01381 4.83e-53 - - - S - - - ASCH
LAPPPGAB_01382 3.9e-91 - 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
LAPPPGAB_01383 4.82e-147 - - - S - - - EDD domain protein, DegV family
LAPPPGAB_01384 7.27e-87 - - - S - - - Uncharacterised protein family (UPF0236)
LAPPPGAB_01385 5.64e-31 - - - S - - - Uncharacterised protein family (UPF0236)
LAPPPGAB_01388 3.74e-75 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
LAPPPGAB_01390 8.41e-296 - - - S - - - COG0433 Predicted ATPase
LAPPPGAB_01391 3.91e-54 - - - - - - - -
LAPPPGAB_01394 5.71e-169 - - - NU - - - StbA protein
LAPPPGAB_01395 1.42e-108 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
LAPPPGAB_01396 2.33e-29 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LAPPPGAB_01408 4.04e-55 - - - S - - - PD-(D/E)XK nuclease family transposase
LAPPPGAB_01410 3.42e-115 epsE2 - - M - - - Bacterial sugar transferase
LAPPPGAB_01411 4.69e-162 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
LAPPPGAB_01412 1.21e-141 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
LAPPPGAB_01413 5.47e-118 ywqD - - D - - - Capsular exopolysaccharide family
LAPPPGAB_01414 1.88e-96 epsB - - M - - - biosynthesis protein
LAPPPGAB_01415 7.9e-42 - 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Bacterial transferase hexapeptide (six repeats)
LAPPPGAB_01416 1.35e-125 - - - - - - - -
LAPPPGAB_01417 1.14e-108 - - - M - - - Glycosyl transferases group 1
LAPPPGAB_01418 1e-81 - - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LAPPPGAB_01420 8.2e-78 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
LAPPPGAB_01421 6.08e-100 - - - M - - - Glycosyltransferase, group 2 family protein
LAPPPGAB_01422 1.12e-144 cps2J - - S - - - Polysaccharide biosynthesis protein
LAPPPGAB_01423 3.37e-41 - 2.3.1.79 - M ko:K00661 - ko00000,ko01000 Glycosyltransferase Family 4
LAPPPGAB_01424 7.53e-133 - - - M - - - PFAM Glycosyl transferase, group 1
LAPPPGAB_01428 1.84e-110 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LAPPPGAB_01430 2.34e-145 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
LAPPPGAB_01431 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LAPPPGAB_01432 1.51e-168 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LAPPPGAB_01433 9.15e-56 - - - E - - - GDSL-like Lipase/Acylhydrolase
LAPPPGAB_01434 8.37e-60 yqhL - - P - - - Rhodanese-like protein
LAPPPGAB_01435 8.22e-203 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LAPPPGAB_01436 1.74e-34 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
LAPPPGAB_01437 9.08e-90 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
LAPPPGAB_01438 2.55e-49 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LAPPPGAB_01439 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LAPPPGAB_01441 3.62e-88 yciQ - - P - - - membrane protein (DUF2207)
LAPPPGAB_01442 2.16e-58 - - - S - - - mazG nucleotide pyrophosphohydrolase
LAPPPGAB_01443 1.96e-119 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LAPPPGAB_01444 3.28e-35 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LAPPPGAB_01445 7.41e-41 ynzC - - S - - - UPF0291 protein
LAPPPGAB_01446 1.29e-106 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LAPPPGAB_01447 1.17e-235 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LAPPPGAB_01448 1.19e-64 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LAPPPGAB_01449 6.31e-154 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
LAPPPGAB_01450 4.39e-104 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LAPPPGAB_01451 1.44e-23 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LAPPPGAB_01452 6.07e-184 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LAPPPGAB_01453 3.32e-133 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LAPPPGAB_01454 7.18e-47 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LAPPPGAB_01455 1.4e-60 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
LAPPPGAB_01456 3.77e-123 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LAPPPGAB_01457 1.45e-48 - - - S - - - Protein conserved in bacteria
LAPPPGAB_01458 1.14e-147 - - - - - - - -
LAPPPGAB_01459 4.27e-143 - - - - - - - -
LAPPPGAB_01460 1.01e-171 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
LAPPPGAB_01461 1.6e-24 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LAPPPGAB_01462 1.19e-151 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LAPPPGAB_01465 8.97e-43 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LAPPPGAB_01469 4.17e-12 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LAPPPGAB_01471 2.96e-124 - - - L - - - helicase
LAPPPGAB_01475 7.59e-78 - - - NU - - - StbA protein
LAPPPGAB_01478 1.29e-246 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
LAPPPGAB_01479 7.15e-182 - - - V - - - RRXRR protein
LAPPPGAB_01482 3.7e-24 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LAPPPGAB_01483 2.91e-53 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
LAPPPGAB_01484 5.44e-20 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LAPPPGAB_01485 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
LAPPPGAB_01486 2.21e-47 - - - - - - - -
LAPPPGAB_01488 3.22e-161 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
LAPPPGAB_01489 5.79e-84 licT - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
LAPPPGAB_01490 2.25e-34 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LAPPPGAB_01491 3.77e-288 - - - L - - - Probable transposase
LAPPPGAB_01492 1.37e-65 - - - L - - - Protein involved in initiation of plasmid replication
LAPPPGAB_01496 3.19e-59 tnpR1 - - L - - - Resolvase, N terminal domain
LAPPPGAB_01497 1.6e-69 - - - S - - - Bacterial protein of unknown function (DUF961)
LAPPPGAB_01498 1.39e-83 - - - S - - - Bacterial protein of unknown function (DUF961)
LAPPPGAB_01499 0.0 XK27_03330 - - J ko:K18220 - br01600,ko00000,ko01504 elongation factor G
LAPPPGAB_01500 2.34e-41 - - - - - - - -
LAPPPGAB_01501 1.8e-33 - - - L - - - Transposase
LAPPPGAB_01502 4.37e-70 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
LAPPPGAB_01503 6.75e-113 nanK - - GK - - - ROK family
LAPPPGAB_01504 4.39e-162 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
LAPPPGAB_01505 4.52e-118 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LAPPPGAB_01506 4.68e-95 - - - K - - - Helix-turn-helix domain, rpiR family
LAPPPGAB_01507 1.86e-45 yphA - - GM - - - NAD dependent epimerase/dehydratase family
LAPPPGAB_01508 1.25e-270 potE - - E - - - Amino Acid
LAPPPGAB_01509 1.16e-08 - - - - - - - -
LAPPPGAB_01510 5.44e-43 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LAPPPGAB_01511 5.1e-205 fusA1 - - J - - - elongation factor G
LAPPPGAB_01512 8.86e-53 fusA1 - - J - - - elongation factor G
LAPPPGAB_01513 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LAPPPGAB_01514 2.32e-45 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LAPPPGAB_01515 9.35e-54 tal 2.2.1.2 - F ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LAPPPGAB_01516 7.62e-217 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LAPPPGAB_01517 5.87e-151 - 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Alcohol dehydrogenase GroES-like domain
LAPPPGAB_01518 7.25e-234 gatC - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
LAPPPGAB_01519 4.74e-48 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
LAPPPGAB_01520 1.06e-51 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
LAPPPGAB_01521 9.75e-78 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
LAPPPGAB_01522 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
LAPPPGAB_01528 2.32e-58 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
LAPPPGAB_01529 3.39e-194 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LAPPPGAB_01530 1.73e-32 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
LAPPPGAB_01533 8.96e-58 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
LAPPPGAB_01536 1.8e-69 - - - S - - - Fic/DOC family
LAPPPGAB_01537 8.42e-261 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LAPPPGAB_01538 4.54e-11 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
LAPPPGAB_01540 1.79e-15 - - - K - - - Protein of unknown function (DUF4065)
LAPPPGAB_01542 2.48e-54 - - - S - - - Protein of unknown function (DUF4065)
LAPPPGAB_01546 3.21e-31 XK27_00515 - - D - - - Glucan-binding protein C
LAPPPGAB_01548 3.61e-79 uspA3 - - T - - - universal stress protein
LAPPPGAB_01550 2.92e-264 - - - E ko:K03294 - ko00000 Amino Acid
LAPPPGAB_01551 3.54e-150 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
LAPPPGAB_01552 1.73e-311 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
LAPPPGAB_01553 3.13e-85 lutC - - S ko:K00782 - ko00000 LUD domain
LAPPPGAB_01554 1.37e-184 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LAPPPGAB_01555 3.5e-18 - - - - - - - -
LAPPPGAB_01556 1.53e-154 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
LAPPPGAB_01557 3.69e-237 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LAPPPGAB_01558 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LAPPPGAB_01559 2.44e-49 yrzL - - S - - - Belongs to the UPF0297 family
LAPPPGAB_01560 3.16e-78 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LAPPPGAB_01561 4.23e-44 yrzB - - S - - - Belongs to the UPF0473 family
LAPPPGAB_01562 3.67e-17 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LAPPPGAB_01563 3.86e-20 cvpA - - S - - - Colicin V production protein
LAPPPGAB_01564 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LAPPPGAB_01565 5.23e-54 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LAPPPGAB_01566 3.82e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LAPPPGAB_01567 6.48e-89 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LAPPPGAB_01568 7.37e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LAPPPGAB_01569 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LAPPPGAB_01570 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LAPPPGAB_01571 1.38e-192 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LAPPPGAB_01572 4.51e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LAPPPGAB_01573 1.81e-201 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LAPPPGAB_01574 1.1e-257 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LAPPPGAB_01575 2.29e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
LAPPPGAB_01576 8.2e-65 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LAPPPGAB_01577 3.1e-137 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LAPPPGAB_01578 2.06e-253 nupG - - F ko:K16323 - ko00000,ko02000 Nucleoside
LAPPPGAB_01579 1.17e-152 - - - S - - - Conserved hypothetical protein 698
LAPPPGAB_01580 1.77e-67 - - - K - - - LysR substrate binding domain
LAPPPGAB_01582 1.7e-84 icaB - - G - - - Polysaccharide deacetylase
LAPPPGAB_01583 3.46e-39 - - - S - - - Belongs to the HesB IscA family
LAPPPGAB_01585 9.69e-90 gshR 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
LAPPPGAB_01586 2.21e-229 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_01587 0.0 proWX - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LAPPPGAB_01590 6.29e-127 cadD - - P - - - Cadmium resistance transporter
LAPPPGAB_01593 1.67e-33 - - - L - - - Helix-turn-helix domain
LAPPPGAB_01594 4.26e-89 - - - P - - - ArsC family
LAPPPGAB_01595 5.9e-190 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LAPPPGAB_01596 1.87e-293 hpk7 2.7.13.3 - T ko:K10681 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LAPPPGAB_01597 4.81e-151 - - - K - - - response regulator
LAPPPGAB_01598 1.61e-44 - - - S - - - Domain of unknown function DUF302
LAPPPGAB_01599 5.25e-22 - - - S - - - Domain of unknown function DUF302
LAPPPGAB_01600 1.4e-53 - - - S ko:K08982 - ko00000 membrane protein (DUF2078)
LAPPPGAB_01601 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 haloacid dehalogenase-like hydrolase
LAPPPGAB_01602 1.74e-103 - - - K - - - Penicillinase repressor
LAPPPGAB_01604 1.33e-53 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
LAPPPGAB_01605 8.93e-35 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LAPPPGAB_01606 3.18e-73 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
LAPPPGAB_01607 3.25e-153 ylbM - - S - - - Belongs to the UPF0348 family
LAPPPGAB_01608 1.86e-103 - - - H - - - Nodulation protein S (NodS)
LAPPPGAB_01609 4.81e-66 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LAPPPGAB_01610 3.44e-91 yqeK - - H - - - Hydrolase, HD family
LAPPPGAB_01611 1.43e-98 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LAPPPGAB_01612 1.36e-40 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
LAPPPGAB_01613 2.41e-228 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
LAPPPGAB_01614 3.33e-91 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
LAPPPGAB_01615 5.01e-69 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LAPPPGAB_01616 4.44e-34 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LAPPPGAB_01617 1.25e-102 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LAPPPGAB_01618 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LAPPPGAB_01619 4.01e-137 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LAPPPGAB_01620 1.95e-94 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
LAPPPGAB_01621 1.04e-85 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LAPPPGAB_01622 3.51e-61 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LAPPPGAB_01623 2.43e-136 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LAPPPGAB_01624 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LAPPPGAB_01625 6.22e-197 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LAPPPGAB_01626 1.73e-134 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
LAPPPGAB_01627 4.59e-121 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LAPPPGAB_01628 3.47e-276 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter transmembrane region
LAPPPGAB_01629 1.34e-254 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
LAPPPGAB_01630 5.29e-178 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
LAPPPGAB_01631 2.61e-244 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
LAPPPGAB_01632 8.1e-204 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
LAPPPGAB_01633 7.12e-50 - - - M - - - LysM domain
LAPPPGAB_01634 5.6e-25 - - - P - - - Rhodanese Homology Domain
LAPPPGAB_01635 2.83e-66 - - - M - - - LysM domain protein
LAPPPGAB_01636 4.52e-115 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
LAPPPGAB_01637 4.26e-108 - - - C - - - Domain of unknown function (DUF4931)
LAPPPGAB_01639 2.61e-89 - - - O - - - ADP-ribosylglycohydrolase
LAPPPGAB_01640 2.6e-130 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LAPPPGAB_01641 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LAPPPGAB_01642 3.98e-92 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
LAPPPGAB_01643 9.9e-105 ylmH - - S - - - S4 domain protein
LAPPPGAB_01644 8.19e-27 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
LAPPPGAB_01645 8.14e-43 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LAPPPGAB_01646 4.52e-229 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LAPPPGAB_01647 6.07e-240 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LAPPPGAB_01648 6.44e-76 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LAPPPGAB_01649 1.05e-195 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LAPPPGAB_01650 4.21e-233 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LAPPPGAB_01651 3.64e-172 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LAPPPGAB_01652 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LAPPPGAB_01653 1.05e-13 ftsL - - D - - - Essential cell division protein
LAPPPGAB_01654 3.67e-180 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LAPPPGAB_01655 2.65e-82 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LAPPPGAB_01657 5.43e-196 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Amino acid kinase family
LAPPPGAB_01658 1.79e-122 ybcH - - D ko:K06889 - ko00000 Alpha beta
LAPPPGAB_01659 9.26e-138 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
LAPPPGAB_01660 1.41e-115 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_01661 3.02e-122 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
LAPPPGAB_01662 7.95e-163 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LAPPPGAB_01663 4.14e-97 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LAPPPGAB_01664 1.33e-70 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
LAPPPGAB_01665 1.64e-121 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LAPPPGAB_01666 3.89e-206 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
LAPPPGAB_01667 1.96e-29 - - - K ko:K03704 - ko00000,ko03000 Cold shock
LAPPPGAB_01668 2.27e-102 radC - - L ko:K03630 - ko00000 DNA repair protein
LAPPPGAB_01669 8.51e-170 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LAPPPGAB_01670 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LAPPPGAB_01671 1.44e-248 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LAPPPGAB_01672 6.91e-205 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
LAPPPGAB_01673 1.31e-222 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LAPPPGAB_01674 6.33e-73 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LAPPPGAB_01675 5.9e-130 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LAPPPGAB_01676 2.92e-31 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
LAPPPGAB_01677 5.46e-246 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
LAPPPGAB_01679 6.35e-97 uspA - - T - - - universal stress protein
LAPPPGAB_01680 8.49e-70 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
LAPPPGAB_01681 2.1e-252 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LAPPPGAB_01682 1.7e-157 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
LAPPPGAB_01684 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LAPPPGAB_01685 0.0 - - - S - - - membrane
LAPPPGAB_01686 3.03e-104 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LAPPPGAB_01687 4.7e-266 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LAPPPGAB_01688 1.68e-128 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
LAPPPGAB_01689 3.04e-179 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LAPPPGAB_01691 1.68e-22 - - - - - - - -
LAPPPGAB_01692 5.9e-254 oatA - - I - - - Acyltransferase
LAPPPGAB_01693 1.65e-272 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LAPPPGAB_01694 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LAPPPGAB_01695 9.92e-178 - 1.1.1.29 - C ko:K00018 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LAPPPGAB_01698 1.72e-41 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LAPPPGAB_01699 7.28e-93 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LAPPPGAB_01700 3.55e-79 yslB - - S - - - Protein of unknown function (DUF2507)
LAPPPGAB_01701 1.2e-155 yhgE - - V ko:K01421 - ko00000 domain protein
LAPPPGAB_01702 0.000904 - - - S - - - zinc-ribbon domain
LAPPPGAB_01704 8.68e-159 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LAPPPGAB_01705 1.28e-216 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
LAPPPGAB_01706 1.48e-148 ydbI - - K - - - AI-2E family transporter
LAPPPGAB_01707 4.18e-76 - - - EG - - - EamA-like transporter family
LAPPPGAB_01708 1.3e-97 nt5e 3.1.3.18 - L ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
LAPPPGAB_01709 4.86e-148 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
LAPPPGAB_01710 7.71e-80 - 1.5.1.38 - S ko:K00299 ko00740,ko00920,ko01100,map00740,map00920,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LAPPPGAB_01711 4.16e-118 - - - C - - - Luciferase-like monooxygenase
LAPPPGAB_01712 9.29e-108 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
LAPPPGAB_01713 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LAPPPGAB_01716 9.41e-63 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LAPPPGAB_01717 2.24e-70 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LAPPPGAB_01724 2.04e-25 ps105 - - - - - - -
LAPPPGAB_01725 6.56e-50 blpT - - - - - - -
LAPPPGAB_01726 1.47e-113 - - - S - - - Haloacid dehalogenase-like hydrolase
LAPPPGAB_01727 1.37e-18 - - - - - - - -
LAPPPGAB_01729 2.02e-35 - - - M - - - Glycosyl transferases group 1
LAPPPGAB_01730 1.39e-105 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
LAPPPGAB_01731 6.76e-54 ywnA - - K - - - Transcriptional regulator
LAPPPGAB_01732 3.4e-41 - - - S - - - CHY zinc finger
LAPPPGAB_01733 1.07e-105 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
LAPPPGAB_01735 2.29e-51 ybbB - - S - - - Protein of unknown function (DUF1211)
LAPPPGAB_01736 4.47e-29 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
LAPPPGAB_01738 3.92e-52 - - - M - - - Acetyltransferase (GNAT) family
LAPPPGAB_01739 3.26e-93 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
LAPPPGAB_01740 1.05e-82 - - - H - - - Methyltransferase domain
LAPPPGAB_01746 3.05e-84 - - - L - - - Transposase
LAPPPGAB_01747 1.66e-102 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
LAPPPGAB_01748 3.8e-46 - - - L - - - Transposase and inactivated derivatives, IS30 family
LAPPPGAB_01749 3.1e-23 - - - K - - - Cro/C1-type HTH DNA-binding domain
LAPPPGAB_01750 2.89e-06 - - - V - - - KxYKxGKxW signal domain protein
LAPPPGAB_01752 1.39e-46 - - - D - - - nuclear chromosome segregation
LAPPPGAB_01753 3.68e-169 - - - L - - - Transposase
LAPPPGAB_01754 8.3e-91 - - - L - - - Transposase
LAPPPGAB_01755 2.84e-26 - - - L - - - Transposase
LAPPPGAB_01761 3.02e-100 tnpR1 - - L - - - Resolvase, N terminal domain
LAPPPGAB_01762 2.93e-33 - - - L - - - Transposase domain (DUF772)
LAPPPGAB_01763 1.94e-192 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LAPPPGAB_01764 6.77e-288 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LAPPPGAB_01765 3.07e-181 - - - V - - - Pfam:Methyltransf_26
LAPPPGAB_01768 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LAPPPGAB_01769 9.53e-263 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LAPPPGAB_01770 1.8e-32 ywiB - - S - - - Domain of unknown function (DUF1934)
LAPPPGAB_01771 7.06e-57 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LAPPPGAB_01772 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LAPPPGAB_01775 4.42e-253 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LAPPPGAB_01776 3.9e-240 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LAPPPGAB_01777 2.05e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LAPPPGAB_01778 6.42e-79 - - - - - - - -
LAPPPGAB_01779 5.47e-309 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
LAPPPGAB_01780 1.8e-33 - - - L - - - Transposase
LAPPPGAB_01781 3.93e-45 - - - S - - - Enterocin A Immunity
LAPPPGAB_01782 5.18e-281 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
LAPPPGAB_01783 1.17e-25 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
LAPPPGAB_01784 3.38e-95 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
LAPPPGAB_01785 2.79e-284 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LAPPPGAB_01786 1.38e-195 yacL - - S - - - domain protein
LAPPPGAB_01787 1.05e-312 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LAPPPGAB_01788 2.26e-263 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LAPPPGAB_01789 2.43e-73 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LAPPPGAB_01790 1.88e-138 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LAPPPGAB_01791 2.69e-81 mipB 2.2.1.2 - H ko:K00616,ko:K08314 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
LAPPPGAB_01792 2.36e-47 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
LAPPPGAB_01793 1.48e-173 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
LAPPPGAB_01794 1.93e-106 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
LAPPPGAB_01795 4.94e-57 srlM1 - - K - - - Glucitol operon activator protein (GutM)
LAPPPGAB_01796 7.68e-93 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LAPPPGAB_01797 1.37e-140 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
LAPPPGAB_01798 2.4e-55 - - - M - - - by MetaGeneAnnotator
LAPPPGAB_01800 1.59e-11 - - - - - - - -
LAPPPGAB_01802 7.04e-06 - - - S - - - Phage minor structural protein GP20
LAPPPGAB_01809 6.16e-12 - - - K - - - Cro/C1-type HTH DNA-binding domain
LAPPPGAB_01815 4.73e-05 - - - L - - - Transposase
LAPPPGAB_01819 2.22e-143 - - - K - - - Primase C terminal 1 (PriCT-1)
LAPPPGAB_01820 2.07e-52 - - - K - - - Transcriptional regulator
LAPPPGAB_01821 3.11e-252 FbpA - - K - - - Fibronectin-binding protein
LAPPPGAB_01822 1.96e-54 - - - - - - - -
LAPPPGAB_01823 1.32e-41 - - - K - - - GNAT family
LAPPPGAB_01824 5.6e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LAPPPGAB_01825 1.46e-277 gdhA 1.4.1.3, 1.4.1.4 - E ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
LAPPPGAB_01826 1.47e-45 - - - O - - - ADP-ribosylglycohydrolase
LAPPPGAB_01827 8.86e-274 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LAPPPGAB_01828 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LAPPPGAB_01829 1.45e-72 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LAPPPGAB_01830 5.39e-120 - - - M - - - Phosphotransferase enzyme family
LAPPPGAB_01831 8.34e-132 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LAPPPGAB_01832 8.22e-30 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LAPPPGAB_01833 7.57e-153 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LAPPPGAB_01834 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LAPPPGAB_01835 3.13e-177 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LAPPPGAB_01836 7.17e-192 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LAPPPGAB_01837 3.18e-115 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LAPPPGAB_01838 1.4e-238 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LAPPPGAB_01839 1.38e-145 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LAPPPGAB_01840 4.31e-73 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LAPPPGAB_01841 1.33e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LAPPPGAB_01842 7.35e-69 yloU - - S - - - Asp23 family, cell envelope-related function
LAPPPGAB_01843 1.21e-302 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
LAPPPGAB_01844 1.91e-306 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LAPPPGAB_01845 7.63e-181 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LAPPPGAB_01846 9.72e-35 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LAPPPGAB_01847 4.17e-129 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LAPPPGAB_01848 6.58e-289 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LAPPPGAB_01849 1.84e-186 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LAPPPGAB_01850 6.15e-53 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LAPPPGAB_01851 1.49e-261 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LAPPPGAB_01852 1.32e-55 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LAPPPGAB_01853 4.89e-38 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LAPPPGAB_01854 2.27e-74 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LAPPPGAB_01855 2.74e-145 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LAPPPGAB_01856 2.19e-78 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
LAPPPGAB_01857 3.56e-250 - - - E ko:K03294 - ko00000 amino acid
LAPPPGAB_01858 2.49e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LAPPPGAB_01859 1.33e-43 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LAPPPGAB_01860 2.6e-53 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LAPPPGAB_01861 7.62e-147 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LAPPPGAB_01862 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LAPPPGAB_01863 0.000113 - - - S - - - Tetratricopeptide repeat
LAPPPGAB_01864 9.71e-274 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LAPPPGAB_01865 4.78e-246 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LAPPPGAB_01866 2.59e-251 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LAPPPGAB_01867 3.87e-315 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LAPPPGAB_01868 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LAPPPGAB_01869 1.47e-30 ykzG - - S - - - Belongs to the UPF0356 family
LAPPPGAB_01870 4.97e-33 - - - - - - - -
LAPPPGAB_01871 1.36e-111 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LAPPPGAB_01872 1.86e-22 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the LDH MDH superfamily
LAPPPGAB_01873 3.57e-33 yktA - - S - - - Belongs to the UPF0223 family
LAPPPGAB_01874 1.22e-95 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
LAPPPGAB_01875 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LAPPPGAB_01876 1.09e-187 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
LAPPPGAB_01877 7.81e-147 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
LAPPPGAB_01878 2.92e-189 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
LAPPPGAB_01879 2.31e-125 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LAPPPGAB_01880 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LAPPPGAB_01881 8.16e-24 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
LAPPPGAB_01882 3.53e-94 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
LAPPPGAB_01883 3.35e-65 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LAPPPGAB_01884 5.17e-167 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LAPPPGAB_01885 8.62e-123 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LAPPPGAB_01886 1.85e-40 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LAPPPGAB_01887 9.96e-132 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LAPPPGAB_01888 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LAPPPGAB_01889 5.27e-284 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LAPPPGAB_01890 6.96e-175 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LAPPPGAB_01891 1.4e-95 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LAPPPGAB_01892 8.46e-293 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LAPPPGAB_01893 5.32e-200 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LAPPPGAB_01894 1.34e-113 - - - S - - - Acyltransferase family
LAPPPGAB_01896 4.03e-12 - - - S - - - Protein of unknown function (DUF805)
LAPPPGAB_01899 1.04e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
LAPPPGAB_01900 9.75e-06 xre - - K - - - XRE family transcriptional regulator
LAPPPGAB_01902 9.51e-83 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_01903 1.91e-17 - - - S - - - Acyltransferase family
LAPPPGAB_01904 1.8e-33 - - - L - - - Transposase
LAPPPGAB_01905 2.16e-125 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
LAPPPGAB_01906 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
LAPPPGAB_01908 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
LAPPPGAB_01909 8.56e-90 - - - L - - - Phage integrase, N-terminal SAM-like domain
LAPPPGAB_01914 4.47e-281 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
LAPPPGAB_01915 3.68e-148 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
LAPPPGAB_01916 1.5e-179 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
LAPPPGAB_01917 3.54e-126 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LAPPPGAB_01918 3.23e-45 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LAPPPGAB_01919 1.15e-53 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
LAPPPGAB_01920 9.19e-304 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
LAPPPGAB_01921 8.07e-120 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LAPPPGAB_01922 3.3e-16 - 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 Lysin motif
LAPPPGAB_01923 5.63e-195 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LAPPPGAB_01924 3.03e-183 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
LAPPPGAB_01925 2.04e-69 ykuP - - C ko:K03839 - ko00000 Flavodoxin
LAPPPGAB_01926 3.97e-69 gtcA - - S - - - Teichoic acid glycosylation protein
LAPPPGAB_01927 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LAPPPGAB_01928 4.44e-98 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
LAPPPGAB_01929 3.37e-27 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
LAPPPGAB_01930 7.83e-63 - - - L - - - Probable transposase
LAPPPGAB_01932 3.53e-230 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LAPPPGAB_01933 6.22e-81 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
LAPPPGAB_01934 3.29e-224 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LAPPPGAB_01935 2.28e-283 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LAPPPGAB_01936 1.5e-40 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LAPPPGAB_01937 1.53e-181 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LAPPPGAB_01939 5e-64 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LAPPPGAB_01940 3.98e-66 - - - K - - - Cro/C1-type HTH DNA-binding domain
LAPPPGAB_01941 5.76e-19 - - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
LAPPPGAB_01942 2.02e-18 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LAPPPGAB_01946 1.25e-92 ywlG - - S - - - Belongs to the UPF0340 family
LAPPPGAB_01947 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
LAPPPGAB_01948 2.11e-122 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LAPPPGAB_01949 6e-76 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LAPPPGAB_01950 1.19e-118 - - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LAPPPGAB_01951 1.73e-66 - - - C - - - Oxidoreductase NAD-binding domain
LAPPPGAB_01952 4.59e-16 - - - S - - - YjcQ protein
LAPPPGAB_01953 3.22e-140 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
LAPPPGAB_01954 1.23e-34 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
LAPPPGAB_01955 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LAPPPGAB_01956 1.73e-49 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LAPPPGAB_01957 2.68e-76 - - - G - - - Xylose isomerase domain protein TIM barrel
LAPPPGAB_01958 4.65e-193 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LAPPPGAB_01959 4.83e-258 - - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LAPPPGAB_01960 6.36e-95 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
LAPPPGAB_01961 1.05e-143 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
LAPPPGAB_01962 5.79e-54 yitW - - S - - - Iron-sulfur cluster assembly protein
LAPPPGAB_01963 2.27e-86 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
LAPPPGAB_01964 9.31e-103 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
LAPPPGAB_01965 1.41e-237 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LAPPPGAB_01966 1.09e-218 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LAPPPGAB_01967 1.46e-141 csrR - - K - - - response regulator
LAPPPGAB_01969 4.68e-137 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
LAPPPGAB_01970 3.59e-285 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LAPPPGAB_01971 3.15e-200 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LAPPPGAB_01972 1.89e-75 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LAPPPGAB_01973 4.68e-119 dgk1 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
LAPPPGAB_01974 1.82e-49 - - - - - - - -
LAPPPGAB_01975 2.37e-290 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LAPPPGAB_01976 4.86e-82 - - - C - - - FMN binding
LAPPPGAB_01977 1.24e-260 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LAPPPGAB_01978 9.07e-86 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LAPPPGAB_01979 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LAPPPGAB_01982 1.8e-33 - - - L - - - Transposase
LAPPPGAB_01983 4.22e-202 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LAPPPGAB_01984 2.61e-163 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
LAPPPGAB_01985 2.92e-164 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LAPPPGAB_01986 3.45e-36 ykuJ - - S - - - Protein of unknown function (DUF1797)
LAPPPGAB_01987 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
LAPPPGAB_01991 3.3e-38 - - - L - - - four-way junction helicase activity
LAPPPGAB_01992 5.99e-52 - - - S - - - Protein of unknown function (DUF4065)
LAPPPGAB_01993 1.11e-33 - - - - - - - -
LAPPPGAB_01994 4.71e-16 - - - T - - - PFAM SpoVT AbrB
LAPPPGAB_01995 1.95e-39 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
LAPPPGAB_01996 7.44e-100 - - - S - - - Fic/DOC family
LAPPPGAB_01997 1.05e-08 - - - K - - - sequence-specific DNA binding
LAPPPGAB_01998 2.4e-37 - - - D - - - nuclear chromosome segregation
LAPPPGAB_02000 4.07e-135 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_02001 2.52e-08 - - - D - - - to surface antigen proteins, peptidoglycan bound protein (LPXTG motif)
LAPPPGAB_02003 8.91e-95 - - - DM - - - Glucan-binding protein C
LAPPPGAB_02005 3.26e-74 - - - - - - - -
LAPPPGAB_02006 4.97e-24 - - - L - - - Protein of unknown function (DUF3991)
LAPPPGAB_02007 7.39e-202 topA2 5.99.1.2 - G ko:K03169 - ko00000,ko01000,ko03032 Topoisomerase IA
LAPPPGAB_02010 4.94e-181 - - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LAPPPGAB_02014 5.65e-265 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
LAPPPGAB_02015 6.66e-86 - - - - - - - -
LAPPPGAB_02018 2.24e-235 - - - U - - - type IV secretory pathway VirB4
LAPPPGAB_02020 1.88e-34 - - - M - - - CHAP domain
LAPPPGAB_02023 3.12e-55 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_02024 1.26e-34 - - - - - - - -
LAPPPGAB_02025 5e-100 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LAPPPGAB_02026 4.69e-126 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LAPPPGAB_02027 2.97e-101 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LAPPPGAB_02028 5.66e-66 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LAPPPGAB_02029 6.11e-73 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LAPPPGAB_02030 5.01e-99 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
LAPPPGAB_02031 2.63e-89 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
LAPPPGAB_02032 3.44e-129 bsh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LAPPPGAB_02036 4.43e-181 xerS - - L ko:K04763 - ko00000,ko03036 Phage integrase family
LAPPPGAB_02037 4.15e-90 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LAPPPGAB_02038 1.12e-33 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LAPPPGAB_02039 1.41e-67 - - - - - - - -
LAPPPGAB_02041 2.87e-242 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
LAPPPGAB_02042 6.41e-206 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
LAPPPGAB_02043 3.01e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
LAPPPGAB_02044 1.51e-75 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
LAPPPGAB_02045 7.99e-130 cadD - - P - - - Cadmium resistance transporter
LAPPPGAB_02046 3.93e-34 - - - K - - - Helix-turn-helix domain
LAPPPGAB_02047 3.7e-44 - - - S - - - Phage derived protein Gp49-like (DUF891)
LAPPPGAB_02048 2.9e-52 - - - L - - - Resolvase, N terminal domain
LAPPPGAB_02054 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
LAPPPGAB_02055 3.87e-42 - - - P - - - Heavy-metal-associated domain
LAPPPGAB_02056 9.39e-121 - - - M - - - Prophage endopeptidase tail
LAPPPGAB_02057 0.0 rny - - D ko:K12088,ko:K18682 ko03018,ko05120,map03018,map05120 ko00000,ko00001,ko00002,ko01000,ko02044,ko03019 peptidase
LAPPPGAB_02058 4.71e-181 - - - S - - - Phage tail protein
LAPPPGAB_02059 0.0 - - - L - - - Phage tail tape measure protein TP901
LAPPPGAB_02060 6.77e-147 ddh 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
LAPPPGAB_02061 3.14e-172 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
LAPPPGAB_02062 3.83e-36 - - - K - - - Helix-turn-helix XRE-family like proteins
LAPPPGAB_02063 2.81e-146 repE - - K - - - Primase C terminal 1 (PriCT-1)
LAPPPGAB_02067 9.01e-57 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Pts system
LAPPPGAB_02068 1.36e-207 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LAPPPGAB_02069 7.79e-44 - - - S - - - Replication initiator protein A (RepA) N-terminus
LAPPPGAB_02070 4.6e-142 - - - L - - - Initiator Replication protein
LAPPPGAB_02072 8.32e-21 ywzB - - S - - - Protein of unknown function (DUF1146)
LAPPPGAB_02073 1.71e-261 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LAPPPGAB_02074 1.5e-211 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
LAPPPGAB_02075 2.29e-36 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LAPPPGAB_02076 6.63e-21 - - - S - - - Protein of unknown function (DUF2969)
LAPPPGAB_02077 2.21e-236 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LAPPPGAB_02078 9.86e-36 spxA 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LAPPPGAB_02079 1.8e-33 - - - L - - - Transposase
LAPPPGAB_02080 5.41e-147 - - - S - - - Glycosyl transferase family 2
LAPPPGAB_02081 3.2e-81 - - - D - - - peptidase
LAPPPGAB_02082 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LAPPPGAB_02083 9.87e-184 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LAPPPGAB_02084 2.26e-130 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LAPPPGAB_02085 5.4e-215 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LAPPPGAB_02086 4.87e-163 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LAPPPGAB_02088 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
LAPPPGAB_02089 1.5e-22 - - - - - - - -
LAPPPGAB_02090 5.69e-49 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
LAPPPGAB_02091 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LAPPPGAB_02092 5.39e-189 - - - E - - - Major Facilitator Superfamily
LAPPPGAB_02093 8.04e-212 yclK - - T - - - Histidine kinase
LAPPPGAB_02094 1.95e-134 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
LAPPPGAB_02095 3.5e-168 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LAPPPGAB_02096 3.21e-98 - - - M - - - LPXTG-motif cell wall anchor domain protein
LAPPPGAB_02100 2.89e-22 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
LAPPPGAB_02101 9.46e-50 - - - - - - - -
LAPPPGAB_02105 4.25e-81 - - - S - - - PD-(D/E)XK nuclease family transposase
LAPPPGAB_02106 1.06e-39 - - - L ko:K07483,ko:K07497 - ko00000 Helix-turn-helix domain
LAPPPGAB_02107 5.79e-240 steT - - E ko:K03294 - ko00000 amino acid
LAPPPGAB_02108 1.4e-14 - - - K - - - Acetyltransferase (GNAT) domain
LAPPPGAB_02109 1.95e-186 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
LAPPPGAB_02110 9.33e-68 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
LAPPPGAB_02111 3.74e-101 - - - K - - - rpiR family
LAPPPGAB_02112 1.15e-215 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LAPPPGAB_02113 7.65e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LAPPPGAB_02114 2.82e-140 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LAPPPGAB_02115 6.55e-130 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LAPPPGAB_02116 3.85e-52 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LAPPPGAB_02117 4.58e-183 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LAPPPGAB_02118 5.93e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LAPPPGAB_02119 9.15e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LAPPPGAB_02120 1.62e-149 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LAPPPGAB_02121 8.95e-95 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LAPPPGAB_02122 2.63e-32 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LAPPPGAB_02123 5.05e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LAPPPGAB_02124 2.98e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LAPPPGAB_02125 7.75e-62 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LAPPPGAB_02126 1.61e-119 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LAPPPGAB_02127 4.1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LAPPPGAB_02128 5.17e-86 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LAPPPGAB_02129 4.99e-113 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LAPPPGAB_02130 2.4e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LAPPPGAB_02131 2.08e-106 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LAPPPGAB_02132 1.65e-31 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LAPPPGAB_02133 1.13e-88 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
LAPPPGAB_02134 1.05e-266 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LAPPPGAB_02135 1.27e-142 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LAPPPGAB_02136 7.16e-47 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LAPPPGAB_02137 1.72e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LAPPPGAB_02138 7.34e-74 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LAPPPGAB_02139 1.24e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LAPPPGAB_02140 1.93e-198 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LAPPPGAB_02141 4.47e-71 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LAPPPGAB_02142 2.27e-127 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAPPPGAB_02143 8.76e-140 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAPPPGAB_02144 3.1e-138 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LAPPPGAB_02145 3.6e-159 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LAPPPGAB_02146 1.04e-99 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LAPPPGAB_02147 1.09e-77 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LAPPPGAB_02149 4e-307 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
LAPPPGAB_02150 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LAPPPGAB_02151 5.24e-49 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LAPPPGAB_02152 1.05e-07 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
LAPPPGAB_02153 2.21e-111 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_02154 1.72e-141 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
LAPPPGAB_02155 4.22e-41 - - - K - - - transcriptional regulator (TetR family)
LAPPPGAB_02156 6.4e-111 aad 3.4.13.22 - E ko:K08641 ko01502,ko02020,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LAPPPGAB_02157 0.0 spxB 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LAPPPGAB_02158 5.57e-64 - - - M - - - LysM domain protein
LAPPPGAB_02159 3.79e-145 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LAPPPGAB_02160 1.77e-131 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
LAPPPGAB_02161 2.34e-72 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LAPPPGAB_02162 1.43e-68 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LAPPPGAB_02163 4.09e-261 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LAPPPGAB_02164 3.13e-180 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LAPPPGAB_02165 1.09e-110 - - - S - - - (CBS) domain
LAPPPGAB_02166 8.16e-202 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LAPPPGAB_02167 1.68e-94 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LAPPPGAB_02168 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LAPPPGAB_02169 2.32e-173 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
LAPPPGAB_02170 1.1e-42 yabO - - J - - - S4 domain protein
LAPPPGAB_02171 4.86e-27 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LAPPPGAB_02172 1.23e-62 yabR - - J ko:K07571 - ko00000 RNA binding
LAPPPGAB_02173 3.24e-118 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LAPPPGAB_02174 5.03e-100 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
LAPPPGAB_02175 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LAPPPGAB_02176 1.08e-165 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LAPPPGAB_02177 2.4e-214 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LAPPPGAB_02178 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LAPPPGAB_02182 1.82e-173 ermA 2.1.1.184 - J ko:K00561 - br01600,ko00000,ko01000,ko01504,ko03009 Ribosomal RNA adenine dimethylase
LAPPPGAB_02183 1.33e-23 - - - - - - - -
LAPPPGAB_02185 8.95e-271 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LAPPPGAB_02186 4.07e-213 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LAPPPGAB_02188 2.78e-32 radC - - L ko:K03630 - ko00000 DNA repair protein
LAPPPGAB_02193 1.16e-06 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
LAPPPGAB_02199 1.44e-67 - - - S ko:K06926 - ko00000 AAA domain, putative AbiEii toxin, Type IV TA system
LAPPPGAB_02200 1.73e-33 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LAPPPGAB_02203 3.87e-05 - - - N - - - Bacterial Ig-like domain 2
LAPPPGAB_02208 1.73e-71 - - - L ko:K07491 - ko00000 Transposase IS200 like
LAPPPGAB_02209 1.49e-199 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
LAPPPGAB_02211 1.06e-28 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
LAPPPGAB_02212 6.64e-148 - - - M - - - Glycosyl hydrolases family 25
LAPPPGAB_02213 2.94e-157 yvgN - - C - - - Aldo keto reductase
LAPPPGAB_02214 4.76e-132 - - - S ko:K07089 - ko00000 Predicted permease
LAPPPGAB_02215 4.85e-80 - - - S - - - Sulphur transport
LAPPPGAB_02216 9.43e-23 - - - O - - - Belongs to the sulfur carrier protein TusA family
LAPPPGAB_02217 7.86e-147 - - - P - - - Rhodanese Homology Domain
LAPPPGAB_02219 4.14e-292 prdA 1.21.4.1 - EJ ko:K10793 ko00330,map00330 ko00000,ko00001,ko01000 Glycine/sarcosine/betaine reductase component B subunits
LAPPPGAB_02220 5.49e-35 - - - S - - - Psort location Cytoplasmic, score
LAPPPGAB_02221 1.14e-84 prdB - - S - - - the current gene model (or a revised gene model) may contain a premature stop
LAPPPGAB_02222 2.69e-42 - - - S - - - the current gene model (or a revised gene model) may contain a premature stop
LAPPPGAB_02223 8.38e-92 - - - S - - - An automated process has identified a potential problem with this gene model
LAPPPGAB_02224 6.97e-87 - - - EJ - - - Glycine/sarcosine/betaine reductase component B subunits
LAPPPGAB_02225 2.59e-183 - 5.1.1.4 - E ko:K01777 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Proline racemase
LAPPPGAB_02226 1.37e-123 - - - S - - - Sulfite exporter TauE/SafE
LAPPPGAB_02227 1.08e-280 - - - E - - - amino acid
LAPPPGAB_02228 8.7e-62 yedF - - O - - - Belongs to the sulfur carrier protein TusA family
LAPPPGAB_02230 5.94e-167 selB - - J ko:K03833 - ko00000,ko03012 Elongation factor SelB, winged helix
LAPPPGAB_02231 1.19e-138 - - - E - - - Serine hydroxymethyltransferase
LAPPPGAB_02232 1.21e-142 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis
LAPPPGAB_02233 7.55e-38 - - - S - - - Iron-sulfur cluster assembly protein
LAPPPGAB_02234 1.55e-235 - - - C - - - RnfC Barrel sandwich hybrid domain
LAPPPGAB_02235 1.44e-125 selD 2.7.9.3 - E ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
LAPPPGAB_02236 1.07e-186 - - - S ko:K07112 - ko00000 Sulphur transport
LAPPPGAB_02237 4.23e-38 - - - O - - - Belongs to the sulfur carrier protein TusA family
LAPPPGAB_02238 9.69e-15 - - - GKT - - - COG3711 Transcriptional antiterminator
LAPPPGAB_02239 1.47e-74 yvbG - - U ko:K05595 - ko00000,ko02000 MarC family integral membrane protein
LAPPPGAB_02240 1.35e-230 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
LAPPPGAB_02241 2.57e-63 - - - S - - - Membrane
LAPPPGAB_02242 2.48e-91 - - - K - - - helix_turn_helix, arabinose operon control protein
LAPPPGAB_02243 6.67e-239 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
LAPPPGAB_02244 4.42e-273 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LAPPPGAB_02245 8.21e-53 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
LAPPPGAB_02246 2.02e-276 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
LAPPPGAB_02247 9.17e-141 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
LAPPPGAB_02248 1.23e-202 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
LAPPPGAB_02249 1.01e-240 XK27_11280 - - S - - - Psort location CytoplasmicMembrane, score
LAPPPGAB_02251 2.42e-113 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_02252 2.73e-71 - - - L ko:K07491 - ko00000 Transposase IS200 like
LAPPPGAB_02253 1.68e-109 - - - L ko:K07496 - ko00000 Transposase, IS605 OrfB family
LAPPPGAB_02254 2.29e-09 - - - L - - - Belongs to the 'phage' integrase family
LAPPPGAB_02256 2.44e-63 hsdM 2.1.1.72 - L ko:K03427 - ko00000,ko01000,ko02048 HsdM N-terminal domain
LAPPPGAB_02258 1.08e-107 - - - S - - - Protein of unknown function (DUF4238)
LAPPPGAB_02259 1.05e-83 - - - - - - - -
LAPPPGAB_02260 5.74e-184 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
LAPPPGAB_02261 1.27e-12 - - - - - - - -
LAPPPGAB_02263 1.11e-104 potE2 - - E ko:K03294 - ko00000 amino acid
LAPPPGAB_02264 6.39e-147 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LAPPPGAB_02265 1.53e-73 - - - K - - - Domain of unknown function (DUF1836)
LAPPPGAB_02266 4.92e-104 yitS - - S - - - EDD domain protein, DegV family
LAPPPGAB_02267 4.83e-60 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LAPPPGAB_02269 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
LAPPPGAB_02270 4.58e-287 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
LAPPPGAB_02271 2.14e-97 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 PFAM restriction modification system DNA specificity domain
LAPPPGAB_02272 2.59e-85 - - - - - - - -
LAPPPGAB_02273 4.2e-147 - - - O - - - AAA domain (Cdc48 subfamily)
LAPPPGAB_02274 4.29e-254 - - - L - - - transposition, DNA-mediated
LAPPPGAB_02275 2.46e-122 - - - J - - - Aminoglycoside-2''-adenylyltransferase
LAPPPGAB_02276 5.31e-102 spoVK - - O ko:K06413 - ko00000 PFAM ATPase family associated with various cellular activities (AAA)
LAPPPGAB_02281 2.73e-25 - - - S - - - HicA toxin of bacterial toxin-antitoxin,
LAPPPGAB_02282 1.04e-19 - - - S - - - protein encoded in hypervariable junctions of pilus gene clusters
LAPPPGAB_02295 1.75e-161 - - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
LAPPPGAB_02296 2.64e-07 - - - S - - - peptidoglycan binding
LAPPPGAB_02298 3.12e-301 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LAPPPGAB_02299 1.78e-21 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
LAPPPGAB_02300 1.92e-128 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
LAPPPGAB_02301 6.57e-109 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
LAPPPGAB_02302 2.65e-75 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 SecY translocase
LAPPPGAB_02303 3.76e-172 - - - S - - - interspecies interaction between organisms
LAPPPGAB_02304 9.6e-261 glpT - - G ko:K02445 - ko00000,ko02000 glycerol-3-phosphate transporter
LAPPPGAB_02305 2.26e-93 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LAPPPGAB_02306 4.78e-189 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
LAPPPGAB_02307 2.94e-147 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
LAPPPGAB_02308 1.37e-40 - - - S - - - YjbR
LAPPPGAB_02309 3.35e-100 yycI - - S - - - YycH protein
LAPPPGAB_02310 1.07e-125 yycH - - S - - - YycH protein
LAPPPGAB_02311 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LAPPPGAB_02312 2.43e-151 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LAPPPGAB_02313 2.53e-146 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
LAPPPGAB_02314 9.53e-134 yxeH - - S - - - hydrolase
LAPPPGAB_02316 6.62e-106 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
LAPPPGAB_02318 1.11e-286 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
LAPPPGAB_02319 3.56e-268 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LAPPPGAB_02320 4.68e-41 - - - K - - - Transcriptional regulator, MarR family
LAPPPGAB_02321 7.47e-217 - - - S - - - Putative peptidoglycan binding domain
LAPPPGAB_02323 2.51e-31 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
LAPPPGAB_02324 2.06e-80 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LAPPPGAB_02325 4.63e-175 - 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 Iron-containing alcohol dehydrogenase
LAPPPGAB_02326 2.01e-224 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LAPPPGAB_02327 2.04e-137 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LAPPPGAB_02328 1.3e-277 pepF - - E - - - Oligopeptidase F
LAPPPGAB_02329 4.69e-121 yicL - - EG - - - EamA-like transporter family
LAPPPGAB_02330 6.27e-90 - - - J - - - Acetyltransferase (GNAT) domain
LAPPPGAB_02331 3.74e-212 - - - S - - - Putative threonine/serine exporter
LAPPPGAB_02332 8.94e-141 - - - U ko:K05340 - ko00000,ko02000 sugar transport
LAPPPGAB_02333 1.12e-11 yobS - - K - - - Bacterial regulatory proteins, tetR family
LAPPPGAB_02334 1.05e-191 - - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
LAPPPGAB_02335 3.32e-136 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LAPPPGAB_02336 7.54e-284 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
LAPPPGAB_02337 7.19e-290 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LAPPPGAB_02338 5.01e-22 yneR - - - - - - -
LAPPPGAB_02339 3.25e-307 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LAPPPGAB_02340 5.27e-53 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LAPPPGAB_02342 1.3e-48 - - - S - - - Protein of unknown function (DUF1211)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)