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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKNGKOGP_00001	9.72e-146	-	-	-	S	-	-	-	membrane
HKNGKOGP_00002	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKNGKOGP_00003	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HKNGKOGP_00004	0.0	-	-	-	S	-	-	-	membrane
HKNGKOGP_00005	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKNGKOGP_00006	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKNGKOGP_00007	3.24e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKNGKOGP_00008	4.73e-17	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HKNGKOGP_00009	2.6e-125	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HKNGKOGP_00010	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HKNGKOGP_00011	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HKNGKOGP_00012	6.61e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HKNGKOGP_00013	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HKNGKOGP_00014	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HKNGKOGP_00015	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HKNGKOGP_00016	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKNGKOGP_00017	1.57e-84	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HKNGKOGP_00018	6.45e-30	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKNGKOGP_00019	4.84e-285	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKNGKOGP_00020	4.11e-206	-	-	-	-	-	-	-	-
HKNGKOGP_00021	1.34e-232	-	-	-	-	-	-	-	-
HKNGKOGP_00022	4.14e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HKNGKOGP_00023	5.37e-74	-	-	-	-	-	-	-	-
HKNGKOGP_00024	2.97e-41	-	-	-	-	-	-	-	-
HKNGKOGP_00028	9.81e-27	-	-	-	-	-	-	-	-
HKNGKOGP_00029	1.11e-122	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_00030	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKNGKOGP_00031	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HKNGKOGP_00032	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKNGKOGP_00033	1e-247	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKNGKOGP_00034	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKNGKOGP_00035	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HKNGKOGP_00036	5.46e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKNGKOGP_00037	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKNGKOGP_00038	3.99e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKNGKOGP_00039	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKNGKOGP_00040	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKNGKOGP_00041	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKNGKOGP_00042	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKNGKOGP_00043	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKNGKOGP_00044	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_00045	2.89e-134	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_00046	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKNGKOGP_00047	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_00048	2.38e-72	-	-	-	-	-	-	-	-
HKNGKOGP_00049	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKNGKOGP_00050	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKNGKOGP_00051	6.32e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKNGKOGP_00052	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKNGKOGP_00053	3.1e-144	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKNGKOGP_00054	2.35e-38	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKNGKOGP_00055	5.05e-187	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKNGKOGP_00056	7.26e-125	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKNGKOGP_00057	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKNGKOGP_00058	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKNGKOGP_00059	2e-208	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKNGKOGP_00060	2.22e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKNGKOGP_00061	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKNGKOGP_00062	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKNGKOGP_00063	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKNGKOGP_00064	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HKNGKOGP_00065	9.68e-276	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKNGKOGP_00066	1.69e-183	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKNGKOGP_00067	1.79e-243	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKNGKOGP_00068	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKNGKOGP_00069	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKNGKOGP_00070	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKNGKOGP_00071	7.71e-298	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKNGKOGP_00072	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKNGKOGP_00073	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKNGKOGP_00074	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKNGKOGP_00075	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKNGKOGP_00076	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKNGKOGP_00077	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKNGKOGP_00078	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKNGKOGP_00079	1.03e-66	-	-	-	-	-	-	-	-
HKNGKOGP_00080	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKNGKOGP_00081	1.1e-112	-	-	-	-	-	-	-	-
HKNGKOGP_00082	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKNGKOGP_00083	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKNGKOGP_00085	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HKNGKOGP_00086	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HKNGKOGP_00087	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKNGKOGP_00088	6.06e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HKNGKOGP_00089	1.51e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HKNGKOGP_00090	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKNGKOGP_00091	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKNGKOGP_00092	1.45e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HKNGKOGP_00093	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HKNGKOGP_00094	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKNGKOGP_00095	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HKNGKOGP_00096	1.38e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HKNGKOGP_00097	1.56e-251	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKNGKOGP_00098	2.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKNGKOGP_00099	2.79e-185	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_00100	8.02e-230	yneE	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_00101	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKNGKOGP_00102	1.97e-230	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKNGKOGP_00103	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKNGKOGP_00104	2.97e-216	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HKNGKOGP_00105	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKNGKOGP_00106	3.11e-289	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKNGKOGP_00107	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKNGKOGP_00108	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HKNGKOGP_00109	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HKNGKOGP_00110	2.62e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKNGKOGP_00111	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HKNGKOGP_00112	5.4e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HKNGKOGP_00113	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HKNGKOGP_00114	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKNGKOGP_00115	1.07e-206	-	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_00116	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HKNGKOGP_00117	2.66e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKNGKOGP_00118	2.46e-120	-	-	-	K	-	-	-	transcriptional regulator
HKNGKOGP_00119	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_00120	6.56e-193	-	-	-	O	-	-	-	Band 7 protein
HKNGKOGP_00121	3.02e-40	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKNGKOGP_00125	6.07e-14	-	-	-	-	-	-	-	-
HKNGKOGP_00127	4.25e-71	-	-	-	-	-	-	-	-
HKNGKOGP_00128	1.42e-39	-	-	-	-	-	-	-	-
HKNGKOGP_00129	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKNGKOGP_00130	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HKNGKOGP_00131	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKNGKOGP_00132	2.05e-55	-	-	-	-	-	-	-	-
HKNGKOGP_00133	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HKNGKOGP_00134	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKNGKOGP_00135	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKNGKOGP_00136	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKNGKOGP_00137	1.51e-48	-	-	-	-	-	-	-	-
HKNGKOGP_00138	5.79e-21	-	-	-	-	-	-	-	-
HKNGKOGP_00139	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HKNGKOGP_00140	4e-40	-	-	-	S	-	-	-	CsbD-like
HKNGKOGP_00141	1.06e-53	-	-	-	-	-	-	-	-
HKNGKOGP_00142	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKNGKOGP_00143	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKNGKOGP_00144	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKNGKOGP_00145	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKNGKOGP_00146	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HKNGKOGP_00147	1.52e-67	-	-	-	-	-	-	-	-
HKNGKOGP_00148	2.12e-57	-	-	-	-	-	-	-	-
HKNGKOGP_00149	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKNGKOGP_00150	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKNGKOGP_00151	1.57e-191	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKNGKOGP_00152	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKNGKOGP_00153	2.06e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKNGKOGP_00154	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKNGKOGP_00155	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKNGKOGP_00156	9.23e-245	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKNGKOGP_00157	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKNGKOGP_00158	2.01e-160	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKNGKOGP_00159	2.93e-88	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKNGKOGP_00160	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKNGKOGP_00161	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HKNGKOGP_00162	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKNGKOGP_00163	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HKNGKOGP_00164	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKNGKOGP_00165	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKNGKOGP_00166	4.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HKNGKOGP_00167	9.85e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKNGKOGP_00168	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_00169	5.51e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKNGKOGP_00170	1.31e-109	-	-	-	T	-	-	-	Universal stress protein family
HKNGKOGP_00171	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_00172	4.86e-235	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKNGKOGP_00173	8.37e-231	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKNGKOGP_00174	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKNGKOGP_00175	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKNGKOGP_00176	2.03e-140	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKNGKOGP_00177	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKNGKOGP_00179	1.52e-281	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKNGKOGP_00180	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKNGKOGP_00181	3.65e-308	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKNGKOGP_00182	1.7e-185	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKNGKOGP_00183	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
HKNGKOGP_00184	1.59e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HKNGKOGP_00185	3.32e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HKNGKOGP_00186	1.66e-61	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_00187	5.01e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HKNGKOGP_00188	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
HKNGKOGP_00189	2.37e-90	XK27_05710	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_00190	5.46e-157	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKNGKOGP_00191	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNGKOGP_00192	6.79e-249	-	-	-	-	-	-	-	-
HKNGKOGP_00193	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HKNGKOGP_00194	2.44e-267	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HKNGKOGP_00195	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HKNGKOGP_00196	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HKNGKOGP_00197	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKNGKOGP_00198	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKNGKOGP_00199	1.96e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKNGKOGP_00200	1.1e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKNGKOGP_00201	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HKNGKOGP_00202	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKNGKOGP_00203	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HKNGKOGP_00204	4.75e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKNGKOGP_00205	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HKNGKOGP_00207	7.51e-166	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HKNGKOGP_00208	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HKNGKOGP_00209	2.46e-108	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HKNGKOGP_00210	1.58e-52	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HKNGKOGP_00212	5.37e-117	-	-	-	F	-	-	-	NUDIX domain
HKNGKOGP_00213	2.42e-71	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_00214	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HKNGKOGP_00215	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_00216	2.25e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKNGKOGP_00217	2.03e-100	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HKNGKOGP_00218	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKNGKOGP_00219	3.03e-40	-	-	-	-	-	-	-	-
HKNGKOGP_00220	2.37e-65	-	-	-	-	-	-	-	-
HKNGKOGP_00221	2.82e-190	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HKNGKOGP_00222	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKNGKOGP_00224	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HKNGKOGP_00225	2.07e-158	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HKNGKOGP_00226	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HKNGKOGP_00227	1.38e-32	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKNGKOGP_00228	5.42e-266	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKNGKOGP_00229	2.79e-181	-	-	-	-	-	-	-	-
HKNGKOGP_00230	7.79e-78	-	-	-	-	-	-	-	-
HKNGKOGP_00231	2.27e-31	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKNGKOGP_00232	3.25e-302	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKNGKOGP_00233	7.87e-289	-	-	-	-	-	-	-	-
HKNGKOGP_00234	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HKNGKOGP_00235	2.46e-240	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKNGKOGP_00236	7.51e-202	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKNGKOGP_00237	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKNGKOGP_00238	1.34e-120	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKNGKOGP_00239	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_00240	7.91e-305	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKNGKOGP_00241	3.81e-64	-	-	-	-	-	-	-	-
HKNGKOGP_00242	4.8e-310	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HKNGKOGP_00243	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKNGKOGP_00244	5.95e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKNGKOGP_00245	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HKNGKOGP_00246	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKNGKOGP_00247	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKNGKOGP_00248	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKNGKOGP_00249	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_00250	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKNGKOGP_00251	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKNGKOGP_00252	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKNGKOGP_00253	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKNGKOGP_00254	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKNGKOGP_00255	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKNGKOGP_00256	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HKNGKOGP_00257	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKNGKOGP_00258	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKNGKOGP_00259	2.91e-178	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKNGKOGP_00260	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKNGKOGP_00261	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKNGKOGP_00262	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKNGKOGP_00263	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HKNGKOGP_00264	4.24e-187	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKNGKOGP_00265	6.04e-18	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKNGKOGP_00266	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HKNGKOGP_00267	1.75e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKNGKOGP_00268	2.48e-252	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HKNGKOGP_00269	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_00270	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HKNGKOGP_00271	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKNGKOGP_00272	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HKNGKOGP_00273	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKNGKOGP_00274	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKNGKOGP_00275	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKNGKOGP_00276	1.54e-191	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKNGKOGP_00277	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_00278	6.46e-109	-	-	-	-	-	-	-	-
HKNGKOGP_00279	1.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKNGKOGP_00280	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKNGKOGP_00281	3.71e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKNGKOGP_00282	5.96e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HKNGKOGP_00283	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKNGKOGP_00284	2.64e-180	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKNGKOGP_00285	1.12e-108	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKNGKOGP_00286	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKNGKOGP_00287	8.64e-81	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKNGKOGP_00288	2.71e-15	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKNGKOGP_00289	0.000676	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKNGKOGP_00290	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HKNGKOGP_00291	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKNGKOGP_00292	5.38e-249	-	-	-	S	-	-	-	Helix-turn-helix domain
HKNGKOGP_00293	2.1e-117	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKNGKOGP_00294	3.85e-55	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKNGKOGP_00295	3.22e-92	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKNGKOGP_00296	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKNGKOGP_00297	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKNGKOGP_00298	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKNGKOGP_00299	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKNGKOGP_00300	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HKNGKOGP_00301	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HKNGKOGP_00302	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKNGKOGP_00303	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKNGKOGP_00304	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKNGKOGP_00305	2.52e-163	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKNGKOGP_00306	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HKNGKOGP_00307	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_00308	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_00309	7.83e-60	-	-	-	-	-	-	-	-
HKNGKOGP_00310	9.96e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HKNGKOGP_00311	1.03e-65	-	-	-	-	-	-	-	-
HKNGKOGP_00312	2.7e-75	-	-	-	S	-	-	-	Putative metallopeptidase domain
HKNGKOGP_00313	5.61e-206	-	-	-	S	-	-	-	Putative metallopeptidase domain
HKNGKOGP_00314	1.15e-282	-	-	-	S	-	-	-	associated with various cellular activities
HKNGKOGP_00315	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKNGKOGP_00316	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HKNGKOGP_00317	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKNGKOGP_00318	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKNGKOGP_00319	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HKNGKOGP_00320	4.73e-242	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_00321	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKNGKOGP_00322	2.49e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HKNGKOGP_00323	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKNGKOGP_00324	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HKNGKOGP_00325	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKNGKOGP_00326	1.31e-128	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKNGKOGP_00327	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKNGKOGP_00328	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_00329	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKNGKOGP_00330	5.14e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKNGKOGP_00331	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKNGKOGP_00332	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HKNGKOGP_00333	2.72e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HKNGKOGP_00334	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKNGKOGP_00335	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKNGKOGP_00336	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKNGKOGP_00337	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_00338	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HKNGKOGP_00339	4.07e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HKNGKOGP_00340	1.02e-109	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKNGKOGP_00341	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKNGKOGP_00342	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNGKOGP_00343	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKNGKOGP_00344	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKNGKOGP_00345	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKNGKOGP_00346	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKNGKOGP_00347	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKNGKOGP_00348	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKNGKOGP_00349	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKNGKOGP_00350	9.22e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HKNGKOGP_00351	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKNGKOGP_00352	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKNGKOGP_00353	2.09e-83	-	-	-	-	-	-	-	-
HKNGKOGP_00354	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HKNGKOGP_00355	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HKNGKOGP_00356	1.23e-275	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_00357	9.28e-29	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_00358	1.23e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKNGKOGP_00359	1.76e-204	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HKNGKOGP_00360	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKNGKOGP_00361	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_00362	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_00363	1.07e-199	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKNGKOGP_00364	0.0	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00365	4.72e-286	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
HKNGKOGP_00366	3.37e-110	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_00367	5.19e-221	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_00368	1.17e-96	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00369	1.48e-103	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKNGKOGP_00370	1.73e-178	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKNGKOGP_00371	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_00372	8.71e-202	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKNGKOGP_00373	3.25e-252	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HKNGKOGP_00374	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_00375	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_00376	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_00377	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKNGKOGP_00378	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKNGKOGP_00379	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKNGKOGP_00380	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKNGKOGP_00381	3.92e-130	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HKNGKOGP_00382	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HKNGKOGP_00384	8.95e-225	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKNGKOGP_00385	2.58e-186	yxeH	-	-	S	-	-	-	hydrolase
HKNGKOGP_00386	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKNGKOGP_00387	8.34e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKNGKOGP_00388	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKNGKOGP_00389	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HKNGKOGP_00390	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00391	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00392	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKNGKOGP_00393	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HKNGKOGP_00394	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKNGKOGP_00395	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_00396	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00397	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HKNGKOGP_00398	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKNGKOGP_00399	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKNGKOGP_00400	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKNGKOGP_00401	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HKNGKOGP_00402	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKNGKOGP_00403	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HKNGKOGP_00404	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKNGKOGP_00405	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_00406	5.02e-158	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKNGKOGP_00407	7.62e-290	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HKNGKOGP_00408	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HKNGKOGP_00409	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HKNGKOGP_00410	1.06e-16	-	-	-	-	-	-	-	-
HKNGKOGP_00411	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HKNGKOGP_00412	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HKNGKOGP_00413	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HKNGKOGP_00414	2.04e-171	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKNGKOGP_00415	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKNGKOGP_00416	9.62e-19	-	-	-	-	-	-	-	-
HKNGKOGP_00417	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HKNGKOGP_00418	1.88e-166	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HKNGKOGP_00419	5.11e-308	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HKNGKOGP_00421	1.97e-256	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKNGKOGP_00422	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKNGKOGP_00423	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_00424	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKNGKOGP_00425	4.04e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKNGKOGP_00426	1.45e-162	-	-	-	S	-	-	-	Membrane
HKNGKOGP_00427	1.31e-210	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HKNGKOGP_00428	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
HKNGKOGP_00429	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HKNGKOGP_00430	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HKNGKOGP_00431	4.67e-314	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HKNGKOGP_00432	3.4e-229	rhaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKNGKOGP_00433	1.05e-179	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HKNGKOGP_00435	6.79e-53	-	-	-	-	-	-	-	-
HKNGKOGP_00436	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKNGKOGP_00437	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKNGKOGP_00438	2.66e-270	xylR	-	-	GK	-	-	-	ROK family
HKNGKOGP_00439	1.89e-81	-	-	-	-	-	-	-	-
HKNGKOGP_00440	2.11e-53	-	-	-	-	-	-	-	-
HKNGKOGP_00441	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKNGKOGP_00442	3.32e-210	-	-	-	-	-	-	-	-
HKNGKOGP_00443	4.28e-219	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HKNGKOGP_00444	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HKNGKOGP_00445	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HKNGKOGP_00446	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKNGKOGP_00447	2.12e-72	-	-	-	-	-	-	-	-
HKNGKOGP_00448	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKNGKOGP_00449	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HKNGKOGP_00450	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
HKNGKOGP_00451	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKNGKOGP_00452	5.36e-305	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKNGKOGP_00453	4.02e-151	hpk31	-	-	T	-	-	-	Histidine kinase
HKNGKOGP_00454	1.89e-104	hpk31	-	-	T	-	-	-	Histidine kinase
HKNGKOGP_00455	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HKNGKOGP_00456	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKNGKOGP_00457	3.84e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKNGKOGP_00458	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKNGKOGP_00459	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HKNGKOGP_00460	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKNGKOGP_00461	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HKNGKOGP_00462	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKNGKOGP_00463	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HKNGKOGP_00464	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKNGKOGP_00465	3.51e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKNGKOGP_00466	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HKNGKOGP_00467	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKNGKOGP_00468	1.77e-123	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_00469	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_00470	5.15e-78	-	-	-	EK	-	-	-	Aminotransferase, class I
HKNGKOGP_00471	1.97e-205	-	-	-	EK	-	-	-	Aminotransferase, class I
HKNGKOGP_00472	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKNGKOGP_00473	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_00474	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_00475	1.2e-175	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKNGKOGP_00476	2.53e-126	-	-	-	KT	-	-	-	response to antibiotic
HKNGKOGP_00477	1.72e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_00478	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HKNGKOGP_00479	2.48e-204	-	-	-	S	-	-	-	Putative adhesin
HKNGKOGP_00480	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_00481	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKNGKOGP_00482	6.39e-234	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HKNGKOGP_00483	1.07e-262	-	-	-	S	-	-	-	DUF218 domain
HKNGKOGP_00484	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKNGKOGP_00485	1.76e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_00486	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKNGKOGP_00487	6.26e-101	-	-	-	-	-	-	-	-
HKNGKOGP_00488	1.14e-195	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HKNGKOGP_00489	1.44e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKNGKOGP_00490	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKNGKOGP_00491	1.77e-292	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HKNGKOGP_00492	2.61e-62	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HKNGKOGP_00493	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HKNGKOGP_00494	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_00495	1.03e-21	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HKNGKOGP_00496	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00497	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HKNGKOGP_00498	6.46e-201	-	-	-	GM	-	-	-	NmrA-like family
HKNGKOGP_00499	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_00500	1.32e-124	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HKNGKOGP_00501	6.79e-28	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HKNGKOGP_00503	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKNGKOGP_00504	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
HKNGKOGP_00505	3.32e-135	-	-	-	-	-	-	-	-
HKNGKOGP_00506	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HKNGKOGP_00507	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
HKNGKOGP_00508	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HKNGKOGP_00509	4.06e-180	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKNGKOGP_00510	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_00511	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HKNGKOGP_00512	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HKNGKOGP_00513	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKNGKOGP_00514	1.03e-34	-	-	-	-	-	-	-	-
HKNGKOGP_00515	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HKNGKOGP_00516	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HKNGKOGP_00517	1.04e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HKNGKOGP_00518	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKNGKOGP_00519	5.81e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKNGKOGP_00520	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKNGKOGP_00521	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
HKNGKOGP_00522	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKNGKOGP_00523	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKNGKOGP_00524	7.21e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKNGKOGP_00525	1.45e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKNGKOGP_00526	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKNGKOGP_00528	1.88e-106	-	-	-	-	-	-	-	-
HKNGKOGP_00529	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HKNGKOGP_00531	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKNGKOGP_00532	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKNGKOGP_00533	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKNGKOGP_00534	1.01e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKNGKOGP_00535	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HKNGKOGP_00536	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HKNGKOGP_00537	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HKNGKOGP_00538	7.07e-09	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKNGKOGP_00539	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKNGKOGP_00540	1.63e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKNGKOGP_00542	2.77e-30	-	-	-	-	-	-	-	-
HKNGKOGP_00544	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKNGKOGP_00545	4.79e-272	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HKNGKOGP_00546	5.05e-100	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HKNGKOGP_00547	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKNGKOGP_00548	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HKNGKOGP_00549	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKNGKOGP_00550	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKNGKOGP_00551	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
HKNGKOGP_00552	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKNGKOGP_00553	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_00554	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HKNGKOGP_00555	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKNGKOGP_00556	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_00557	1.56e-98	-	-	-	-	-	-	-	-
HKNGKOGP_00558	1.11e-240	-	-	-	S	-	-	-	Cell surface protein
HKNGKOGP_00559	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_00560	3.11e-193	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HKNGKOGP_00561	2.72e-23	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HKNGKOGP_00562	3.54e-80	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKNGKOGP_00563	3.33e-149	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HKNGKOGP_00564	1.59e-243	ynjC	-	-	S	-	-	-	Cell surface protein
HKNGKOGP_00566	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_00567	1.47e-83	-	-	-	-	-	-	-	-
HKNGKOGP_00568	3.14e-287	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HKNGKOGP_00569	4.13e-157	-	-	-	-	-	-	-	-
HKNGKOGP_00570	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKNGKOGP_00571	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKNGKOGP_00572	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_00574	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKNGKOGP_00575	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKNGKOGP_00576	8.01e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKNGKOGP_00577	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKNGKOGP_00578	1.59e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_00579	5.35e-216	-	-	-	GM	-	-	-	NmrA-like family
HKNGKOGP_00580	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKNGKOGP_00581	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKNGKOGP_00582	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HKNGKOGP_00583	3.64e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKNGKOGP_00584	3.27e-170	-	-	-	S	-	-	-	KR domain
HKNGKOGP_00585	6.76e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_00586	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HKNGKOGP_00587	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKNGKOGP_00588	1.97e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKNGKOGP_00589	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HKNGKOGP_00590	7.57e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_00591	3.49e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HKNGKOGP_00592	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKNGKOGP_00593	2.58e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKNGKOGP_00594	1.35e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKNGKOGP_00595	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_00596	2.13e-167	-	-	-	GM	-	-	-	NmrA-like family
HKNGKOGP_00597	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_00598	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKNGKOGP_00599	1.83e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKNGKOGP_00600	2.97e-56	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_00601	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKNGKOGP_00602	2.22e-235	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKNGKOGP_00603	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_00604	1.23e-268	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HKNGKOGP_00605	2.4e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_00606	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKNGKOGP_00607	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKNGKOGP_00608	4.54e-202	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HKNGKOGP_00609	1.35e-208	-	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_00610	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKNGKOGP_00611	0.0	-	-	-	S	-	-	-	MucBP domain
HKNGKOGP_00612	7.16e-106	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKNGKOGP_00613	1.85e-41	-	-	-	-	-	-	-	-
HKNGKOGP_00615	7.39e-189	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKNGKOGP_00616	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_00617	0.0	-	-	-	G	ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757	ko00010,ko02060,map00010,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_00618	3.21e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKNGKOGP_00619	0.0	-	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKNGKOGP_00620	1.37e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKNGKOGP_00621	2.61e-64	sgaB	2.7.1.194, 2.7.1.200	-	G	ko:K02774,ko:K02822,ko:K03475	ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKNGKOGP_00622	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00623	2.73e-284	-	-	-	S	-	-	-	Membrane
HKNGKOGP_00624	7.29e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HKNGKOGP_00625	5.57e-141	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HKNGKOGP_00626	1.4e-57	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKNGKOGP_00627	8.95e-53	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HKNGKOGP_00628	1.68e-121	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HKNGKOGP_00629	2.23e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HKNGKOGP_00631	3.2e-109	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKNGKOGP_00632	5.04e-92	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKNGKOGP_00633	5.68e-155	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKNGKOGP_00634	1.39e-126	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKNGKOGP_00635	4.71e-47	-	-	-	S	-	-	-	aldo-keto reductase (NADP) activity
HKNGKOGP_00636	5.75e-141	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_00637	1.6e-103	-	-	-	GM	-	-	-	SnoaL-like domain
HKNGKOGP_00638	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
HKNGKOGP_00639	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HKNGKOGP_00640	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_00641	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKNGKOGP_00642	4.09e-253	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNGKOGP_00643	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
HKNGKOGP_00644	0.0	-	-	-	L	-	-	-	MutS domain V
HKNGKOGP_00645	3.85e-234	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HKNGKOGP_00646	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKNGKOGP_00647	2.24e-87	-	-	-	S	-	-	-	NUDIX domain
HKNGKOGP_00648	0.0	-	-	-	S	-	-	-	membrane
HKNGKOGP_00649	1.73e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKNGKOGP_00650	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HKNGKOGP_00651	2.08e-284	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKNGKOGP_00652	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKNGKOGP_00653	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HKNGKOGP_00654	3.39e-138	-	-	-	-	-	-	-	-
HKNGKOGP_00655	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HKNGKOGP_00656	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_00657	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKNGKOGP_00658	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_00659	4.75e-80	-	-	-	-	-	-	-	-
HKNGKOGP_00660	9.24e-246	-	-	-	S	-	-	-	Fn3-like domain
HKNGKOGP_00661	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_00662	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_00663	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKNGKOGP_00664	7.9e-72	-	-	-	-	-	-	-	-
HKNGKOGP_00665	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HKNGKOGP_00666	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_00667	3.32e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_00668	4.08e-12	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HKNGKOGP_00669	1.2e-169	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HKNGKOGP_00670	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKNGKOGP_00671	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKNGKOGP_00672	1.69e-144	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKNGKOGP_00673	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKNGKOGP_00674	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKNGKOGP_00675	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HKNGKOGP_00676	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKNGKOGP_00677	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HKNGKOGP_00678	1.55e-42	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKNGKOGP_00679	1.58e-127	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKNGKOGP_00680	7.08e-309	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HKNGKOGP_00681	1.83e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKNGKOGP_00682	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKNGKOGP_00683	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HKNGKOGP_00684	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKNGKOGP_00685	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKNGKOGP_00687	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKNGKOGP_00688	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKNGKOGP_00689	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKNGKOGP_00690	3.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKNGKOGP_00691	2.71e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKNGKOGP_00692	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HKNGKOGP_00693	4.97e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKNGKOGP_00694	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKNGKOGP_00695	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKNGKOGP_00696	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKNGKOGP_00697	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKNGKOGP_00698	1.15e-61	-	-	-	-	-	-	-	-
HKNGKOGP_00699	8.2e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HKNGKOGP_00700	2.89e-251	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKNGKOGP_00701	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKNGKOGP_00702	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKNGKOGP_00703	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HKNGKOGP_00704	8.64e-112	-	-	-	-	-	-	-	-
HKNGKOGP_00705	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HKNGKOGP_00706	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HKNGKOGP_00707	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HKNGKOGP_00708	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKNGKOGP_00709	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HKNGKOGP_00710	2.13e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKNGKOGP_00711	6.65e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HKNGKOGP_00712	3.55e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKNGKOGP_00713	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKNGKOGP_00714	1.3e-125	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKNGKOGP_00715	8.93e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKNGKOGP_00716	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKNGKOGP_00717	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKNGKOGP_00718	6.56e-154	csrR	-	-	K	-	-	-	response regulator
HKNGKOGP_00719	8.16e-107	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKNGKOGP_00720	1.24e-258	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKNGKOGP_00721	3.95e-90	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKNGKOGP_00722	8.29e-66	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKNGKOGP_00723	1.04e-234	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HKNGKOGP_00724	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HKNGKOGP_00725	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKNGKOGP_00726	1.21e-129	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKNGKOGP_00727	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKNGKOGP_00728	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKNGKOGP_00729	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKNGKOGP_00730	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNGKOGP_00731	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKNGKOGP_00732	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKNGKOGP_00733	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKNGKOGP_00734	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKNGKOGP_00735	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKNGKOGP_00736	1.41e-55	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKNGKOGP_00737	7.43e-28	-	-	-	M	-	-	-	domain protein
HKNGKOGP_00738	2.68e-71	-	-	-	M	-	-	-	domain protein
HKNGKOGP_00739	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HKNGKOGP_00740	4.43e-129	-	-	-	-	-	-	-	-
HKNGKOGP_00741	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKNGKOGP_00742	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKNGKOGP_00743	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_00744	1.63e-231	-	-	-	M	-	-	-	Peptidase family S41
HKNGKOGP_00745	9.03e-42	-	-	-	-	-	-	-	-
HKNGKOGP_00746	5.42e-223	-	-	-	-	-	-	-	-
HKNGKOGP_00747	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNGKOGP_00748	0.0	yhaN	-	-	L	-	-	-	AAA domain
HKNGKOGP_00749	5e-293	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HKNGKOGP_00750	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HKNGKOGP_00751	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKNGKOGP_00752	2.43e-18	-	-	-	-	-	-	-	-
HKNGKOGP_00753	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKNGKOGP_00754	9.65e-272	arcT	-	-	E	-	-	-	Aminotransferase
HKNGKOGP_00755	3.29e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HKNGKOGP_00756	7.85e-122	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HKNGKOGP_00757	1.11e-206	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HKNGKOGP_00758	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKNGKOGP_00759	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKNGKOGP_00760	1.1e-70	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKNGKOGP_00761	1.14e-191	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKNGKOGP_00762	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_00763	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_00764	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_00765	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKNGKOGP_00766	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKNGKOGP_00767	1.75e-221	celR	-	-	K	-	-	-	PRD domain
HKNGKOGP_00768	0.0	celR	-	-	K	-	-	-	PRD domain
HKNGKOGP_00769	6.25e-138	-	-	-	-	-	-	-	-
HKNGKOGP_00770	7.84e-35	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKNGKOGP_00771	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKNGKOGP_00772	3.81e-105	-	-	-	-	-	-	-	-
HKNGKOGP_00773	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKNGKOGP_00774	7.02e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HKNGKOGP_00777	1.79e-42	-	-	-	-	-	-	-	-
HKNGKOGP_00778	2.69e-316	dinF	-	-	V	-	-	-	MatE
HKNGKOGP_00779	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HKNGKOGP_00780	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HKNGKOGP_00781	5.68e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HKNGKOGP_00782	2.24e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HKNGKOGP_00783	1.55e-118	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HKNGKOGP_00784	2.57e-151	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HKNGKOGP_00785	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HKNGKOGP_00786	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKNGKOGP_00787	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKNGKOGP_00788	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HKNGKOGP_00789	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKNGKOGP_00790	3.89e-237	-	-	-	-	-	-	-	-
HKNGKOGP_00791	9.03e-16	-	-	-	-	-	-	-	-
HKNGKOGP_00792	4.29e-87	-	-	-	-	-	-	-	-
HKNGKOGP_00795	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HKNGKOGP_00796	7.12e-62	-	-	-	-	-	-	-	-
HKNGKOGP_00797	8.82e-119	-	-	-	-	-	-	-	-
HKNGKOGP_00798	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_00799	2.55e-77	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_00800	4.92e-50	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_00801	4.56e-78	-	-	-	-	-	-	-	-
HKNGKOGP_00802	5.37e-74	-	-	-	-	-	-	-	-
HKNGKOGP_00803	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKNGKOGP_00804	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKNGKOGP_00805	7.83e-140	-	-	-	-	-	-	-	-
HKNGKOGP_00806	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKNGKOGP_00807	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKNGKOGP_00808	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_00809	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_00810	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKNGKOGP_00811	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HKNGKOGP_00812	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_00813	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HKNGKOGP_00815	7.13e-119	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HKNGKOGP_00816	2.94e-189	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HKNGKOGP_00817	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKNGKOGP_00818	6.38e-36	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKNGKOGP_00819	9.12e-106	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKNGKOGP_00820	1.56e-161	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKNGKOGP_00821	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKNGKOGP_00822	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_00823	4.59e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_00824	4.15e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HKNGKOGP_00825	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKNGKOGP_00826	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HKNGKOGP_00827	1.83e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKNGKOGP_00828	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKNGKOGP_00829	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKNGKOGP_00830	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKNGKOGP_00831	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKNGKOGP_00832	3.54e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HKNGKOGP_00833	9.32e-40	-	-	-	-	-	-	-	-
HKNGKOGP_00834	6.62e-74	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKNGKOGP_00835	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKNGKOGP_00836	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HKNGKOGP_00837	4.99e-31	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HKNGKOGP_00838	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKNGKOGP_00839	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKNGKOGP_00840	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HKNGKOGP_00841	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HKNGKOGP_00842	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HKNGKOGP_00843	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKNGKOGP_00844	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HKNGKOGP_00845	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_00846	1.14e-186	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HKNGKOGP_00847	9.32e-180	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HKNGKOGP_00848	1.56e-64	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HKNGKOGP_00849	4.95e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKNGKOGP_00850	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKNGKOGP_00851	1.79e-211	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKNGKOGP_00852	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKNGKOGP_00853	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKNGKOGP_00854	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HKNGKOGP_00855	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKNGKOGP_00856	1.16e-128	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HKNGKOGP_00857	4.67e-280	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKNGKOGP_00858	2.27e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_00859	4.97e-67	-	2.7.1.194	-	G	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00860	2.09e-141	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00861	2.48e-98	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNGKOGP_00862	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKNGKOGP_00863	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKNGKOGP_00864	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKNGKOGP_00865	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKNGKOGP_00866	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKNGKOGP_00867	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HKNGKOGP_00868	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKNGKOGP_00869	1.23e-109	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKNGKOGP_00870	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKNGKOGP_00871	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKNGKOGP_00872	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKNGKOGP_00873	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKNGKOGP_00874	3.53e-244	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKNGKOGP_00875	1.78e-88	-	-	-	L	-	-	-	nuclease
HKNGKOGP_00876	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKNGKOGP_00877	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKNGKOGP_00878	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKNGKOGP_00879	3.09e-70	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKNGKOGP_00880	1.22e-20	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKNGKOGP_00881	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKNGKOGP_00882	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_00883	1.56e-127	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKNGKOGP_00884	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKNGKOGP_00885	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKNGKOGP_00886	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HKNGKOGP_00887	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HKNGKOGP_00888	3.21e-72	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKNGKOGP_00889	2.93e-92	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKNGKOGP_00890	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKNGKOGP_00891	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKNGKOGP_00892	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKNGKOGP_00893	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HKNGKOGP_00894	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKNGKOGP_00895	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HKNGKOGP_00896	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HKNGKOGP_00897	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKNGKOGP_00898	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKNGKOGP_00899	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKNGKOGP_00900	3.3e-166	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKNGKOGP_00901	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HKNGKOGP_00902	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HKNGKOGP_00903	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKNGKOGP_00904	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HKNGKOGP_00905	6.33e-185	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKNGKOGP_00906	4.82e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HKNGKOGP_00907	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HKNGKOGP_00908	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKNGKOGP_00909	4.93e-93	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKNGKOGP_00910	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKNGKOGP_00911	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HKNGKOGP_00912	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HKNGKOGP_00913	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKNGKOGP_00914	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HKNGKOGP_00915	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKNGKOGP_00916	1e-200	-	-	-	G	-	-	-	Peptidase_C39 like family
HKNGKOGP_00918	8.77e-204	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKNGKOGP_00919	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKNGKOGP_00920	7.89e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKNGKOGP_00921	1.57e-77	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HKNGKOGP_00922	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HKNGKOGP_00923	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HKNGKOGP_00924	5.32e-71	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKNGKOGP_00925	7.47e-37	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKNGKOGP_00926	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKNGKOGP_00927	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKNGKOGP_00928	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKNGKOGP_00929	2.31e-176	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKNGKOGP_00930	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKNGKOGP_00931	8.37e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKNGKOGP_00932	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKNGKOGP_00933	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKNGKOGP_00934	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
HKNGKOGP_00935	3.62e-211	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HKNGKOGP_00936	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HKNGKOGP_00937	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HKNGKOGP_00941	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKNGKOGP_00942	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HKNGKOGP_00945	6.21e-39	-	-	-	-	-	-	-	-
HKNGKOGP_00946	2.43e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKNGKOGP_00947	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKNGKOGP_00948	1.28e-23	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKNGKOGP_00949	6.45e-111	-	-	-	-	-	-	-	-
HKNGKOGP_00950	2.29e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKNGKOGP_00951	9.97e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKNGKOGP_00952	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HKNGKOGP_00953	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKNGKOGP_00954	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HKNGKOGP_00955	1.24e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HKNGKOGP_00956	6.24e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HKNGKOGP_00957	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HKNGKOGP_00958	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKNGKOGP_00959	6.3e-62	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKNGKOGP_00960	6.34e-257	-	-	-	-	-	-	-	-
HKNGKOGP_00961	9.51e-135	-	-	-	-	-	-	-	-
HKNGKOGP_00962	1.94e-201	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HKNGKOGP_00963	4.61e-87	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HKNGKOGP_00964	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_00965	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKNGKOGP_00966	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKNGKOGP_00967	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HKNGKOGP_00968	6.06e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HKNGKOGP_00969	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKNGKOGP_00970	1.05e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKNGKOGP_00971	3.85e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HKNGKOGP_00972	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HKNGKOGP_00973	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKNGKOGP_00974	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKNGKOGP_00975	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKNGKOGP_00976	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKNGKOGP_00977	1.74e-258	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKNGKOGP_00978	5.28e-94	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKNGKOGP_00979	8.14e-94	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKNGKOGP_00980	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKNGKOGP_00981	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKNGKOGP_00982	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKNGKOGP_00983	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKNGKOGP_00984	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKNGKOGP_00985	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKNGKOGP_00986	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HKNGKOGP_00987	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKNGKOGP_00988	5.12e-31	-	-	-	-	-	-	-	-
HKNGKOGP_00989	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKNGKOGP_00990	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_00991	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKNGKOGP_00992	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
HKNGKOGP_00993	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKNGKOGP_00994	3.2e-188	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKNGKOGP_00995	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HKNGKOGP_00996	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HKNGKOGP_00997	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HKNGKOGP_00998	1.99e-237	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HKNGKOGP_00999	1.23e-293	-	-	-	-	-	-	-	-
HKNGKOGP_01000	9.73e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HKNGKOGP_01001	0.0	cps4J	-	-	S	-	-	-	MatE
HKNGKOGP_01002	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKNGKOGP_01003	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HKNGKOGP_01004	1.73e-217	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKNGKOGP_01005	1.72e-148	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKNGKOGP_01006	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKNGKOGP_01007	6.62e-62	-	-	-	-	-	-	-	-
HKNGKOGP_01008	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKNGKOGP_01009	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_01010	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKNGKOGP_01011	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKNGKOGP_01012	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKNGKOGP_01013	7.9e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_01014	2.87e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKNGKOGP_01015	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HKNGKOGP_01016	1.14e-180	-	-	-	Q	-	-	-	Methyltransferase
HKNGKOGP_01017	1.75e-43	-	-	-	-	-	-	-	-
HKNGKOGP_01020	8.61e-54	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKNGKOGP_01021	1.46e-35	-	-	-	S	-	-	-	Belongs to the LOG family
HKNGKOGP_01022	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKNGKOGP_01023	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKNGKOGP_01024	2.48e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_01025	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HKNGKOGP_01026	1.36e-209	-	-	-	GM	-	-	-	NmrA-like family
HKNGKOGP_01027	4.31e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HKNGKOGP_01028	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HKNGKOGP_01029	1.41e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HKNGKOGP_01030	1.7e-70	-	-	-	-	-	-	-	-
HKNGKOGP_01031	1.17e-273	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HKNGKOGP_01032	2.11e-82	-	-	-	-	-	-	-	-
HKNGKOGP_01033	1.11e-111	-	-	-	-	-	-	-	-
HKNGKOGP_01034	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKNGKOGP_01035	2.27e-74	-	-	-	-	-	-	-	-
HKNGKOGP_01036	4.79e-21	-	-	-	-	-	-	-	-
HKNGKOGP_01037	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HKNGKOGP_01038	1.63e-71	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HKNGKOGP_01039	1.69e-190	-	-	-	EG	-	-	-	EamA-like transporter family
HKNGKOGP_01040	2.66e-155	-	-	-	S	-	-	-	membrane
HKNGKOGP_01041	2.55e-145	-	-	-	S	-	-	-	VIT family
HKNGKOGP_01042	5.12e-242	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HKNGKOGP_01043	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKNGKOGP_01044	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HKNGKOGP_01045	4.26e-54	-	-	-	-	-	-	-	-
HKNGKOGP_01046	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HKNGKOGP_01047	7.21e-314	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HKNGKOGP_01048	7.21e-35	-	-	-	-	-	-	-	-
HKNGKOGP_01049	2.55e-65	-	-	-	-	-	-	-	-
HKNGKOGP_01050	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HKNGKOGP_01051	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKNGKOGP_01052	2.52e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKNGKOGP_01053	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKNGKOGP_01054	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKNGKOGP_01055	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKNGKOGP_01056	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKNGKOGP_01057	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKNGKOGP_01058	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKNGKOGP_01059	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
HKNGKOGP_01060	4.97e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKNGKOGP_01061	2.93e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKNGKOGP_01062	3.68e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKNGKOGP_01063	5.41e-174	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKNGKOGP_01064	3.44e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HKNGKOGP_01065	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HKNGKOGP_01066	1.58e-66	-	-	-	-	-	-	-	-
HKNGKOGP_01067	9.81e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HKNGKOGP_01068	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_01069	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKNGKOGP_01070	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_01071	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HKNGKOGP_01072	1.31e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKNGKOGP_01073	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_01074	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HKNGKOGP_01075	4.45e-38	-	-	-	-	-	-	-	-
HKNGKOGP_01076	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HKNGKOGP_01077	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
HKNGKOGP_01078	2.15e-71	-	-	-	-	-	-	-	-
HKNGKOGP_01079	5.77e-81	-	-	-	-	-	-	-	-
HKNGKOGP_01081	5.13e-138	-	-	-	-	-	-	-	-
HKNGKOGP_01082	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HKNGKOGP_01083	4.61e-204	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HKNGKOGP_01084	1.72e-129	-	-	-	K	-	-	-	transcriptional regulator
HKNGKOGP_01085	5.05e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HKNGKOGP_01086	8.41e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKNGKOGP_01087	3.04e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HKNGKOGP_01088	3.28e-231	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKNGKOGP_01089	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HKNGKOGP_01090	8.08e-184	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKNGKOGP_01091	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HKNGKOGP_01092	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HKNGKOGP_01093	1.01e-26	-	-	-	-	-	-	-	-
HKNGKOGP_01094	7.94e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HKNGKOGP_01095	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HKNGKOGP_01096	2.59e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HKNGKOGP_01097	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKNGKOGP_01099	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HKNGKOGP_01100	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNGKOGP_01101	1.08e-172	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNGKOGP_01102	1.93e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_01103	8.41e-109	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNGKOGP_01104	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNGKOGP_01105	7.22e-268	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNGKOGP_01106	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNGKOGP_01107	1e-147	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HKNGKOGP_01108	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKNGKOGP_01109	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKNGKOGP_01110	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKNGKOGP_01111	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKNGKOGP_01112	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKNGKOGP_01113	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKNGKOGP_01114	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKNGKOGP_01115	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKNGKOGP_01116	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKNGKOGP_01117	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKNGKOGP_01118	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKNGKOGP_01119	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKNGKOGP_01120	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKNGKOGP_01121	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKNGKOGP_01122	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKNGKOGP_01123	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKNGKOGP_01124	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKNGKOGP_01125	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKNGKOGP_01126	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKNGKOGP_01127	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKNGKOGP_01128	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKNGKOGP_01129	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKNGKOGP_01130	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKNGKOGP_01131	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKNGKOGP_01132	5.28e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKNGKOGP_01133	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKNGKOGP_01134	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKNGKOGP_01135	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKNGKOGP_01136	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNGKOGP_01137	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKNGKOGP_01138	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKNGKOGP_01139	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HKNGKOGP_01140	2.56e-99	-	-	-	S	-	-	-	NusG domain II
HKNGKOGP_01141	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKNGKOGP_01142	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HKNGKOGP_01143	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNGKOGP_01144	3.42e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKNGKOGP_01145	3.47e-212	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKNGKOGP_01146	2.49e-186	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKNGKOGP_01147	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKNGKOGP_01148	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKNGKOGP_01149	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKNGKOGP_01150	8.51e-210	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKNGKOGP_01151	3.11e-175	-	-	-	S	-	-	-	Membrane
HKNGKOGP_01152	5.68e-27	-	-	-	S	-	-	-	Membrane
HKNGKOGP_01153	9.09e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HKNGKOGP_01154	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKNGKOGP_01155	6.73e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKNGKOGP_01156	4.68e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HKNGKOGP_01157	4.29e-202	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKNGKOGP_01158	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKNGKOGP_01159	6.15e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKNGKOGP_01160	2.01e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HKNGKOGP_01161	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HKNGKOGP_01162	1.92e-244	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_01163	5.24e-195	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKNGKOGP_01164	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKNGKOGP_01165	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKNGKOGP_01166	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKNGKOGP_01167	1.18e-66	-	-	-	-	-	-	-	-
HKNGKOGP_01168	1.07e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKNGKOGP_01169	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKNGKOGP_01170	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HKNGKOGP_01171	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HKNGKOGP_01172	1.07e-241	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKNGKOGP_01173	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HKNGKOGP_01174	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HKNGKOGP_01175	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HKNGKOGP_01176	5.69e-185	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKNGKOGP_01177	6.87e-33	-	-	-	K	-	-	-	sequence-specific DNA binding
HKNGKOGP_01179	1.11e-84	-	-	-	-	-	-	-	-
HKNGKOGP_01180	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HKNGKOGP_01181	9.85e-62	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKNGKOGP_01182	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKNGKOGP_01183	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HKNGKOGP_01184	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKNGKOGP_01185	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HKNGKOGP_01186	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKNGKOGP_01187	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKNGKOGP_01188	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKNGKOGP_01189	1.91e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKNGKOGP_01190	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKNGKOGP_01192	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HKNGKOGP_01193	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HKNGKOGP_01194	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HKNGKOGP_01195	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HKNGKOGP_01196	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKNGKOGP_01197	1.27e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HKNGKOGP_01198	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKNGKOGP_01199	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HKNGKOGP_01200	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HKNGKOGP_01201	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKNGKOGP_01202	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKNGKOGP_01203	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKNGKOGP_01204	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_01205	1.6e-96	-	-	-	-	-	-	-	-
HKNGKOGP_01206	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKNGKOGP_01207	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKNGKOGP_01208	7.85e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKNGKOGP_01209	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKNGKOGP_01210	7.76e-110	ykuL	-	-	S	-	-	-	(CBS) domain
HKNGKOGP_01211	4.53e-122	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HKNGKOGP_01212	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKNGKOGP_01213	2.02e-47	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKNGKOGP_01214	2.26e-115	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKNGKOGP_01215	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKNGKOGP_01216	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKNGKOGP_01217	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKNGKOGP_01218	7.19e-29	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKNGKOGP_01219	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKNGKOGP_01220	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKNGKOGP_01221	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKNGKOGP_01222	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKNGKOGP_01223	1.65e-237	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKNGKOGP_01224	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKNGKOGP_01225	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKNGKOGP_01226	1.03e-60	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKNGKOGP_01227	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKNGKOGP_01228	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKNGKOGP_01229	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKNGKOGP_01230	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKNGKOGP_01231	2.07e-118	-	-	-	-	-	-	-	-
HKNGKOGP_01232	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKNGKOGP_01233	1.35e-93	-	-	-	-	-	-	-	-
HKNGKOGP_01234	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKNGKOGP_01235	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKNGKOGP_01236	1.93e-163	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HKNGKOGP_01237	1.16e-20	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HKNGKOGP_01238	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKNGKOGP_01239	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKNGKOGP_01240	2.21e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKNGKOGP_01241	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKNGKOGP_01242	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HKNGKOGP_01243	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HKNGKOGP_01244	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HKNGKOGP_01245	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKNGKOGP_01246	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKNGKOGP_01247	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKNGKOGP_01248	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HKNGKOGP_01249	1.86e-208	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKNGKOGP_01250	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKNGKOGP_01251	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKNGKOGP_01252	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKNGKOGP_01253	6.64e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HKNGKOGP_01254	4.08e-270	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HKNGKOGP_01255	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKNGKOGP_01256	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HKNGKOGP_01257	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HKNGKOGP_01258	8.73e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HKNGKOGP_01259	4.65e-229	-	-	-	-	-	-	-	-
HKNGKOGP_01260	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HKNGKOGP_01261	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKNGKOGP_01262	5.08e-194	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKNGKOGP_01263	1.23e-262	-	-	-	-	-	-	-	-
HKNGKOGP_01264	2.94e-244	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKNGKOGP_01265	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKNGKOGP_01266	6.97e-209	-	-	-	GK	-	-	-	ROK family
HKNGKOGP_01267	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_01268	1.84e-254	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_01269	1.5e-41	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_01270	5.19e-57	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKNGKOGP_01271	1.05e-06	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKNGKOGP_01272	9.68e-34	-	-	-	-	-	-	-	-
HKNGKOGP_01273	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_01274	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HKNGKOGP_01275	1.57e-240	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKNGKOGP_01276	1.38e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HKNGKOGP_01277	0.0	-	-	-	L	-	-	-	DNA helicase
HKNGKOGP_01278	1.85e-40	-	-	-	-	-	-	-	-
HKNGKOGP_01279	3.34e-147	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_01280	2.75e-145	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_01281	5.04e-155	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_01282	3.26e-124	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_01283	1.49e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HKNGKOGP_01284	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKNGKOGP_01285	8.82e-32	-	-	-	-	-	-	-	-
HKNGKOGP_01286	1.93e-31	plnF	-	-	-	-	-	-	-
HKNGKOGP_01287	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_01288	1.05e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKNGKOGP_01289	2.04e-171	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKNGKOGP_01290	1.71e-300	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKNGKOGP_01291	1.9e-25	plnA	-	-	-	-	-	-	-
HKNGKOGP_01292	1.22e-36	-	-	-	-	-	-	-	-
HKNGKOGP_01293	2.08e-160	plnP	-	-	S	-	-	-	CAAX protease self-immunity
HKNGKOGP_01294	2.18e-274	-	-	-	M	-	-	-	Glycosyl transferase family 2
HKNGKOGP_01296	4.08e-39	-	-	-	-	-	-	-	-
HKNGKOGP_01297	8.53e-34	plnJ	-	-	-	-	-	-	-
HKNGKOGP_01298	3.29e-32	plnK	-	-	-	-	-	-	-
HKNGKOGP_01299	9.76e-153	-	-	-	-	-	-	-	-
HKNGKOGP_01300	6.24e-25	plnR	-	-	-	-	-	-	-
HKNGKOGP_01301	1.15e-43	-	-	-	-	-	-	-	-
HKNGKOGP_01303	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKNGKOGP_01304	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKNGKOGP_01305	8.38e-192	-	-	-	S	-	-	-	hydrolase
HKNGKOGP_01306	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_01307	1.19e-187	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKNGKOGP_01308	7.81e-263	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HKNGKOGP_01309	9.2e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKNGKOGP_01310	5.32e-51	-	-	-	-	-	-	-	-
HKNGKOGP_01311	4.92e-90	-	-	-	S	-	-	-	Immunity protein 63
HKNGKOGP_01312	6.71e-23	-	-	-	-	-	-	-	-
HKNGKOGP_01313	2.59e-84	-	-	-	-	-	-	-	-
HKNGKOGP_01314	2.35e-52	-	-	-	-	-	-	-	-
HKNGKOGP_01315	6.97e-45	-	-	-	-	-	-	-	-
HKNGKOGP_01316	2.27e-77	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HKNGKOGP_01317	0.0	-	-	-	M	-	-	-	domain protein
HKNGKOGP_01318	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKNGKOGP_01319	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HKNGKOGP_01320	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKNGKOGP_01321	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKNGKOGP_01322	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_01323	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKNGKOGP_01324	1.17e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HKNGKOGP_01325	2.82e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_01326	4.27e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKNGKOGP_01327	6.05e-20	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKNGKOGP_01328	1.16e-67	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKNGKOGP_01329	2.16e-103	-	-	-	-	-	-	-	-
HKNGKOGP_01330	8.37e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HKNGKOGP_01331	3.25e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKNGKOGP_01332	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKNGKOGP_01333	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKNGKOGP_01334	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HKNGKOGP_01335	8.1e-76	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKNGKOGP_01336	1.12e-26	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKNGKOGP_01337	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKNGKOGP_01338	8.95e-60	-	-	-	-	-	-	-	-
HKNGKOGP_01339	3.66e-226	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKNGKOGP_01340	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HKNGKOGP_01341	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKNGKOGP_01342	1.18e-121	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKNGKOGP_01343	2.76e-59	-	-	-	-	-	-	-	-
HKNGKOGP_01344	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKNGKOGP_01345	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HKNGKOGP_01346	1.29e-279	-	-	-	-	-	-	-	-
HKNGKOGP_01347	2.25e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKNGKOGP_01348	8.05e-187	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKNGKOGP_01349	5.18e-115	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_01350	7.98e-158	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKNGKOGP_01351	1.19e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HKNGKOGP_01352	1.45e-79	-	-	-	S	-	-	-	CHY zinc finger
HKNGKOGP_01353	2.03e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKNGKOGP_01354	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKNGKOGP_01355	6.4e-54	-	-	-	-	-	-	-	-
HKNGKOGP_01356	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKNGKOGP_01357	3.48e-40	-	-	-	-	-	-	-	-
HKNGKOGP_01358	4.09e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HKNGKOGP_01359	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HKNGKOGP_01361	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HKNGKOGP_01362	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HKNGKOGP_01363	1.08e-243	-	-	-	-	-	-	-	-
HKNGKOGP_01364	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_01365	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKNGKOGP_01366	2.06e-30	-	-	-	-	-	-	-	-
HKNGKOGP_01367	1.24e-116	-	-	-	K	-	-	-	acetyltransferase
HKNGKOGP_01368	1.88e-111	-	-	-	K	-	-	-	GNAT family
HKNGKOGP_01369	8.08e-110	-	-	-	S	-	-	-	ASCH
HKNGKOGP_01370	1.5e-124	-	-	-	K	-	-	-	Cupin domain
HKNGKOGP_01371	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKNGKOGP_01372	9e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_01373	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_01374	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_01375	9.25e-32	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
HKNGKOGP_01377	9.73e-24	-	-	-	-	-	-	-	-
HKNGKOGP_01379	9.97e-50	-	-	-	-	-	-	-	-
HKNGKOGP_01380	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKNGKOGP_01381	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_01382	3.57e-43	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HKNGKOGP_01383	6.31e-36	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HKNGKOGP_01384	9.85e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKNGKOGP_01385	2.03e-75	-	-	-	-	-	-	-	-
HKNGKOGP_01386	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HKNGKOGP_01387	6.88e-170	-	-	-	-	-	-	-	-
HKNGKOGP_01388	9.03e-229	-	-	-	-	-	-	-	-
HKNGKOGP_01389	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HKNGKOGP_01390	1.31e-97	-	-	-	M	-	-	-	LysM domain protein
HKNGKOGP_01391	7.98e-80	-	-	-	M	-	-	-	Lysin motif
HKNGKOGP_01392	2.63e-154	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_01393	9.28e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_01394	1.25e-110	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_01395	1.05e-262	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKNGKOGP_01396	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKNGKOGP_01397	1.96e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKNGKOGP_01398	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKNGKOGP_01399	6.79e-135	-	-	-	K	-	-	-	transcriptional regulator
HKNGKOGP_01400	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKNGKOGP_01401	1.49e-63	-	-	-	-	-	-	-	-
HKNGKOGP_01402	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HKNGKOGP_01403	5.22e-131	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKNGKOGP_01404	2.87e-56	-	-	-	-	-	-	-	-
HKNGKOGP_01405	3.35e-75	-	-	-	-	-	-	-	-
HKNGKOGP_01406	4.13e-166	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_01407	1.06e-111	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_01408	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKNGKOGP_01409	2.42e-65	-	-	-	-	-	-	-	-
HKNGKOGP_01410	1.1e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HKNGKOGP_01411	9.08e-317	hpk2	-	-	T	-	-	-	Histidine kinase
HKNGKOGP_01412	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_01413	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_01414	1.55e-55	-	-	-	-	-	-	-	-
HKNGKOGP_01415	2.92e-57	-	-	-	-	-	-	-	-
HKNGKOGP_01416	1.91e-151	-	-	-	-	-	-	-	-
HKNGKOGP_01417	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKNGKOGP_01418	1.05e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_01419	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_01420	3.2e-91	-	-	-	-	-	-	-	-
HKNGKOGP_01421	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKNGKOGP_01422	2.6e-185	-	-	-	-	-	-	-	-
HKNGKOGP_01423	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKNGKOGP_01424	1.31e-250	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_01425	6.05e-178	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_01426	2.88e-239	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKNGKOGP_01427	2.41e-91	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKNGKOGP_01428	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKNGKOGP_01429	1.61e-34	-	-	-	-	-	-	-	-
HKNGKOGP_01430	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HKNGKOGP_01431	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKNGKOGP_01432	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HKNGKOGP_01433	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKNGKOGP_01434	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKNGKOGP_01435	4.3e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HKNGKOGP_01436	1.82e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HKNGKOGP_01437	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HKNGKOGP_01438	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HKNGKOGP_01439	2.98e-90	-	-	-	-	-	-	-	-
HKNGKOGP_01440	1.22e-125	-	-	-	-	-	-	-	-
HKNGKOGP_01441	3.43e-66	-	-	-	-	-	-	-	-
HKNGKOGP_01442	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKNGKOGP_01443	1.21e-111	-	-	-	-	-	-	-	-
HKNGKOGP_01444	2.15e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HKNGKOGP_01445	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_01446	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HKNGKOGP_01447	7.3e-94	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HKNGKOGP_01448	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_01449	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKNGKOGP_01450	7.02e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_01451	7.88e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HKNGKOGP_01452	2.22e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKNGKOGP_01453	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKNGKOGP_01454	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HKNGKOGP_01455	1.2e-91	-	-	-	-	-	-	-	-
HKNGKOGP_01456	3.68e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKNGKOGP_01457	2.16e-201	dkgB	-	-	S	-	-	-	reductase
HKNGKOGP_01458	5.84e-115	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HKNGKOGP_01459	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HKNGKOGP_01460	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKNGKOGP_01461	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKNGKOGP_01463	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HKNGKOGP_01464	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNGKOGP_01465	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNGKOGP_01466	3.81e-18	-	-	-	-	-	-	-	-
HKNGKOGP_01467	3.89e-126	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKNGKOGP_01468	8.84e-111	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKNGKOGP_01469	8.83e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HKNGKOGP_01470	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HKNGKOGP_01471	6.33e-46	-	-	-	-	-	-	-	-
HKNGKOGP_01472	1.01e-228	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HKNGKOGP_01473	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HKNGKOGP_01474	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKNGKOGP_01475	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNGKOGP_01476	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKNGKOGP_01477	1.21e-34	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_01478	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_01479	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_01480	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKNGKOGP_01482	0.0	-	-	-	M	-	-	-	domain protein
HKNGKOGP_01483	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_01484	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKNGKOGP_01485	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKNGKOGP_01486	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKNGKOGP_01487	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKNGKOGP_01488	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKNGKOGP_01489	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKNGKOGP_01490	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKNGKOGP_01491	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKNGKOGP_01492	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HKNGKOGP_01493	2.12e-314	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HKNGKOGP_01494	1.25e-304	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HKNGKOGP_01495	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKNGKOGP_01496	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKNGKOGP_01497	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HKNGKOGP_01498	7.76e-134	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HKNGKOGP_01499	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_01500	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_01501	4.69e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKNGKOGP_01502	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKNGKOGP_01503	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKNGKOGP_01504	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKNGKOGP_01505	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKNGKOGP_01506	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HKNGKOGP_01507	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HKNGKOGP_01508	9.52e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HKNGKOGP_01509	2.35e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HKNGKOGP_01510	5.78e-40	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_01511	1.45e-56	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_01513	1.61e-98	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HKNGKOGP_01514	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HKNGKOGP_01515	6e-47	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_01516	7.77e-94	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_01517	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HKNGKOGP_01518	2.01e-160	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_01519	5.84e-19	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_01520	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HKNGKOGP_01521	3.37e-115	-	-	-	-	-	-	-	-
HKNGKOGP_01522	3.16e-191	-	-	-	-	-	-	-	-
HKNGKOGP_01523	7.71e-183	-	-	-	-	-	-	-	-
HKNGKOGP_01524	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKNGKOGP_01525	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKNGKOGP_01526	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HKNGKOGP_01527	1.44e-146	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_01528	2.69e-227	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_01529	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKNGKOGP_01530	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
HKNGKOGP_01531	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_01532	4.03e-132	-	-	-	-	-	-	-	-
HKNGKOGP_01533	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKNGKOGP_01534	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HKNGKOGP_01535	6.75e-212	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HKNGKOGP_01536	2.52e-203	morA	-	-	S	-	-	-	reductase
HKNGKOGP_01538	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HKNGKOGP_01539	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKNGKOGP_01540	8.91e-289	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKNGKOGP_01541	3.73e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKNGKOGP_01542	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKNGKOGP_01543	4.45e-99	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_01544	2.01e-141	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKNGKOGP_01545	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HKNGKOGP_01546	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKNGKOGP_01547	2.94e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKNGKOGP_01548	1e-156	-	-	-	-	-	-	-	-
HKNGKOGP_01549	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKNGKOGP_01550	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKNGKOGP_01551	0.0	-	-	-	L	-	-	-	HIRAN domain
HKNGKOGP_01552	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKNGKOGP_01553	1.97e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKNGKOGP_01554	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKNGKOGP_01555	3.03e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKNGKOGP_01556	3.77e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKNGKOGP_01557	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKNGKOGP_01558	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HKNGKOGP_01559	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKNGKOGP_01560	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HKNGKOGP_01561	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKNGKOGP_01562	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HKNGKOGP_01563	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HKNGKOGP_01564	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HKNGKOGP_01565	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HKNGKOGP_01566	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKNGKOGP_01567	4.11e-164	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_01568	1.67e-54	-	-	-	-	-	-	-	-
HKNGKOGP_01569	7.9e-142	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HKNGKOGP_01570	4.07e-05	-	-	-	-	-	-	-	-
HKNGKOGP_01571	4.85e-180	-	-	-	-	-	-	-	-
HKNGKOGP_01572	8.84e-263	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKNGKOGP_01573	4.36e-87	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKNGKOGP_01574	2.38e-99	-	-	-	-	-	-	-	-
HKNGKOGP_01575	9.06e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKNGKOGP_01576	6.34e-215	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKNGKOGP_01577	1.71e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HKNGKOGP_01578	1.02e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKNGKOGP_01579	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKNGKOGP_01580	1.15e-161	-	-	-	S	-	-	-	DJ-1/PfpI family
HKNGKOGP_01581	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HKNGKOGP_01582	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HKNGKOGP_01583	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function
HKNGKOGP_01584	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HKNGKOGP_01585	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HKNGKOGP_01586	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKNGKOGP_01587	1.67e-220	-	-	-	K	-	-	-	WYL domain
HKNGKOGP_01588	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HKNGKOGP_01589	1.65e-106	-	-	-	S	-	-	-	ASCH
HKNGKOGP_01590	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HKNGKOGP_01591	3.97e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKNGKOGP_01592	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKNGKOGP_01593	1.54e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKNGKOGP_01594	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKNGKOGP_01595	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKNGKOGP_01596	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HKNGKOGP_01597	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HKNGKOGP_01598	4.06e-211	-	-	-	S	-	-	-	KR domain
HKNGKOGP_01599	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKNGKOGP_01600	2.49e-95	-	-	-	C	-	-	-	FMN binding
HKNGKOGP_01601	1.46e-204	-	-	-	K	-	-	-	LysR family
HKNGKOGP_01602	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKNGKOGP_01603	0.0	-	-	-	C	-	-	-	FMN_bind
HKNGKOGP_01604	5.25e-149	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HKNGKOGP_01605	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HKNGKOGP_01606	4.51e-155	pnb	-	-	C	-	-	-	nitroreductase
HKNGKOGP_01607	3.46e-156	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HKNGKOGP_01608	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HKNGKOGP_01609	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_01610	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKNGKOGP_01611	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HKNGKOGP_01612	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HKNGKOGP_01613	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HKNGKOGP_01614	5.04e-313	yycH	-	-	S	-	-	-	YycH protein
HKNGKOGP_01615	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKNGKOGP_01616	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKNGKOGP_01618	2.54e-50	-	-	-	-	-	-	-	-
HKNGKOGP_01619	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HKNGKOGP_01620	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HKNGKOGP_01621	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HKNGKOGP_01622	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKNGKOGP_01623	8.38e-184	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKNGKOGP_01625	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKNGKOGP_01626	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKNGKOGP_01627	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKNGKOGP_01628	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKNGKOGP_01629	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKNGKOGP_01630	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKNGKOGP_01632	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_01634	3.25e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKNGKOGP_01635	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKNGKOGP_01636	2.35e-285	yttB	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_01637	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKNGKOGP_01638	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKNGKOGP_01639	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKNGKOGP_01640	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKNGKOGP_01641	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKNGKOGP_01642	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKNGKOGP_01643	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNGKOGP_01644	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNGKOGP_01645	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKNGKOGP_01646	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HKNGKOGP_01647	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKNGKOGP_01648	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKNGKOGP_01649	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKNGKOGP_01650	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKNGKOGP_01651	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_01652	2.64e-305	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HKNGKOGP_01653	5.56e-172	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HKNGKOGP_01654	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKNGKOGP_01655	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKNGKOGP_01656	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HKNGKOGP_01657	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKNGKOGP_01659	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_01660	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKNGKOGP_01662	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKNGKOGP_01663	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HKNGKOGP_01664	4.02e-203	degV1	-	-	S	-	-	-	DegV family
HKNGKOGP_01665	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_01666	3.79e-181	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HKNGKOGP_01668	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HKNGKOGP_01669	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HKNGKOGP_01670	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HKNGKOGP_01671	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKNGKOGP_01672	2.55e-232	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKNGKOGP_01673	3.87e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKNGKOGP_01674	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKNGKOGP_01675	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HKNGKOGP_01676	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HKNGKOGP_01677	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HKNGKOGP_01678	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HKNGKOGP_01679	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HKNGKOGP_01680	2.94e-124	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HKNGKOGP_01681	1.26e-98	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HKNGKOGP_01682	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKNGKOGP_01683	1.91e-201	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKNGKOGP_01684	1.48e-247	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HKNGKOGP_01685	0.0	yknV	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_01686	0.0	mdlA2	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKNGKOGP_01687	9.5e-200	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKNGKOGP_01688	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HKNGKOGP_01689	1.29e-231	ypdA	-	-	U	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_01690	1.52e-211	lplC	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_01691	0.0	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Domain of unknown function (DUF3502)
HKNGKOGP_01692	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
HKNGKOGP_01693	1.71e-139	ypcB	-	-	S	-	-	-	integral membrane protein
HKNGKOGP_01694	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKNGKOGP_01695	0.0	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HKNGKOGP_01696	3.76e-212	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKNGKOGP_01697	1.09e-275	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKNGKOGP_01698	0.0	ypdD	-	-	G	-	-	-	Glycosyl hydrolase family 92
HKNGKOGP_01699	1.54e-247	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_01700	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HKNGKOGP_01701	0.0	-	2.3.1.204, 3.2.1.170, 3.2.1.24	GH38	G	ko:K01191,ko:K15524,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolases family 38 N-terminal domain
HKNGKOGP_01702	4.02e-205	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKNGKOGP_01703	0.0	bgl	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_01704	6.56e-28	-	-	-	-	-	-	-	-
HKNGKOGP_01705	3.95e-92	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKNGKOGP_01706	1.28e-35	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNGKOGP_01707	1.09e-122	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKNGKOGP_01708	1.6e-221	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKNGKOGP_01709	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKNGKOGP_01710	5.18e-58	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKNGKOGP_01711	1.02e-155	-	-	-	S	-	-	-	repeat protein
HKNGKOGP_01712	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HKNGKOGP_01713	0.0	-	-	-	N	-	-	-	domain, Protein
HKNGKOGP_01714	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKNGKOGP_01715	5.92e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_01716	9.37e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HKNGKOGP_01717	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HKNGKOGP_01718	2.82e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKNGKOGP_01719	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKNGKOGP_01720	6.59e-87	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKNGKOGP_01721	3.37e-172	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKNGKOGP_01722	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKNGKOGP_01723	7.74e-47	-	-	-	-	-	-	-	-
HKNGKOGP_01724	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKNGKOGP_01725	1.3e-228	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKNGKOGP_01727	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKNGKOGP_01728	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HKNGKOGP_01729	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HKNGKOGP_01730	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKNGKOGP_01731	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKNGKOGP_01732	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKNGKOGP_01733	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKNGKOGP_01734	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKNGKOGP_01735	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKNGKOGP_01736	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKNGKOGP_01737	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKNGKOGP_01738	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKNGKOGP_01739	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HKNGKOGP_01740	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKNGKOGP_01741	1.14e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKNGKOGP_01742	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HKNGKOGP_01743	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKNGKOGP_01744	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKNGKOGP_01745	1.41e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKNGKOGP_01746	1.76e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKNGKOGP_01747	8.82e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKNGKOGP_01749	1.12e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HKNGKOGP_01750	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKNGKOGP_01751	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HKNGKOGP_01752	1.55e-74	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKNGKOGP_01753	1.86e-245	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKNGKOGP_01754	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HKNGKOGP_01755	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKNGKOGP_01756	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKNGKOGP_01757	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKNGKOGP_01758	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HKNGKOGP_01759	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKNGKOGP_01760	3.52e-84	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKNGKOGP_01761	9.43e-144	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKNGKOGP_01762	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKNGKOGP_01763	8.18e-23	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKNGKOGP_01764	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKNGKOGP_01765	2.2e-26	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HKNGKOGP_01766	5.57e-65	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HKNGKOGP_01771	1.23e-172	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HKNGKOGP_01772	2.26e-81	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HKNGKOGP_01773	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HKNGKOGP_01774	0.0	-	-	-	E	-	-	-	Amino Acid
HKNGKOGP_01775	1.74e-185	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKNGKOGP_01776	9.38e-91	-	-	-	-	-	-	-	-
HKNGKOGP_01778	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
HKNGKOGP_01779	1.67e-292	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HKNGKOGP_01780	1.3e-226	-	-	-	O	-	-	-	protein import
HKNGKOGP_01781	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_01782	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_01783	2.31e-277	-	-	-	-	-	-	-	-
HKNGKOGP_01784	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_01785	4.19e-70	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HKNGKOGP_01786	3.3e-87	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HKNGKOGP_01787	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HKNGKOGP_01788	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
HKNGKOGP_01789	1.17e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKNGKOGP_01790	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_01791	7.62e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HKNGKOGP_01792	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_01793	4.63e-91	-	-	-	-	-	-	-	-
HKNGKOGP_01794	2.02e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKNGKOGP_01795	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HKNGKOGP_01796	7.43e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKNGKOGP_01797	3.55e-281	-	-	-	T	-	-	-	diguanylate cyclase
HKNGKOGP_01798	2.72e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HKNGKOGP_01799	4.87e-118	-	-	-	-	-	-	-	-
HKNGKOGP_01800	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKNGKOGP_01801	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HKNGKOGP_01802	9.47e-137	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKNGKOGP_01803	1.44e-128	-	-	-	M	-	-	-	Lysin motif
HKNGKOGP_01804	2.04e-95	-	-	-	M	-	-	-	LysM domain
HKNGKOGP_01805	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_01806	1.57e-237	-	-	-	GM	-	-	-	Male sterility protein
HKNGKOGP_01807	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_01808	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_01809	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_01810	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKNGKOGP_01811	1.02e-193	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_01812	2.86e-72	-	-	-	-	-	-	-	-
HKNGKOGP_01813	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKNGKOGP_01814	2.03e-84	-	-	-	-	-	-	-	-
HKNGKOGP_01815	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HKNGKOGP_01816	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_01818	1.99e-72	-	-	-	-	-	-	-	-
HKNGKOGP_01819	2.8e-19	-	-	-	-	-	-	-	-
HKNGKOGP_01821	8.17e-38	-	-	-	-	-	-	-	-
HKNGKOGP_01822	2.51e-60	-	-	-	-	-	-	-	-
HKNGKOGP_01824	2.05e-32	-	-	-	S	-	-	-	Barstar (barnase inhibitor)
HKNGKOGP_01826	6.17e-71	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HKNGKOGP_01828	2.45e-170	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HKNGKOGP_01829	1.56e-227	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HKNGKOGP_01830	2.81e-282	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKNGKOGP_01831	1.6e-259	cps3D	-	-	-	-	-	-	-
HKNGKOGP_01832	2.92e-145	cps3E	-	-	-	-	-	-	-
HKNGKOGP_01833	3.93e-194	cps3F	-	-	-	-	-	-	-
HKNGKOGP_01834	1.03e-264	cps3H	-	-	-	-	-	-	-
HKNGKOGP_01835	7.13e-101	cps3I	-	-	G	-	-	-	Acyltransferase family
HKNGKOGP_01836	5.81e-132	cps3I	-	-	G	-	-	-	Acyltransferase family
HKNGKOGP_01837	8.42e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKNGKOGP_01838	3.34e-140	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKNGKOGP_01839	0.0	-	-	-	M	-	-	-	domain protein
HKNGKOGP_01840	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_01841	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKNGKOGP_01842	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HKNGKOGP_01843	9.02e-70	-	-	-	-	-	-	-	-
HKNGKOGP_01844	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HKNGKOGP_01845	9.3e-40	-	-	-	-	-	-	-	-
HKNGKOGP_01846	8.39e-38	-	-	-	-	-	-	-	-
HKNGKOGP_01847	4.14e-132	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HKNGKOGP_01848	2.82e-170	-	-	-	-	-	-	-	-
HKNGKOGP_01849	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKNGKOGP_01850	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HKNGKOGP_01851	9.26e-171	lytE	-	-	M	-	-	-	NlpC/P60 family
HKNGKOGP_01852	3.97e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HKNGKOGP_01853	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HKNGKOGP_01854	1.32e-166	pbpX	-	-	V	-	-	-	Beta-lactamase
HKNGKOGP_01856	4.22e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKNGKOGP_01857	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HKNGKOGP_01858	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKNGKOGP_01859	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HKNGKOGP_01860	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKNGKOGP_01861	1e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HKNGKOGP_01862	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKNGKOGP_01863	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKNGKOGP_01864	2.52e-55	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKNGKOGP_01865	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKNGKOGP_01866	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKNGKOGP_01867	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKNGKOGP_01868	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_01869	4.3e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKNGKOGP_01870	2.26e-158	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKNGKOGP_01871	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKNGKOGP_01872	2.14e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKNGKOGP_01873	1.72e-242	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKNGKOGP_01874	4.98e-267	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKNGKOGP_01875	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HKNGKOGP_01876	4.47e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HKNGKOGP_01877	1.85e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKNGKOGP_01878	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HKNGKOGP_01879	7.96e-98	-	-	-	S	-	-	-	(CBS) domain
HKNGKOGP_01880	6.54e-09	-	-	-	S	-	-	-	(CBS) domain
HKNGKOGP_01881	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKNGKOGP_01882	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKNGKOGP_01883	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKNGKOGP_01884	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKNGKOGP_01885	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKNGKOGP_01886	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HKNGKOGP_01888	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKNGKOGP_01889	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HKNGKOGP_01890	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKNGKOGP_01891	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKNGKOGP_01892	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKNGKOGP_01893	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKNGKOGP_01894	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKNGKOGP_01895	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKNGKOGP_01896	1.5e-120	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_01897	2.09e-48	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_01898	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKNGKOGP_01899	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HKNGKOGP_01900	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKNGKOGP_01901	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_01902	0.0	-	-	-	M	-	-	-	domain protein
HKNGKOGP_01903	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKNGKOGP_01904	1.26e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKNGKOGP_01905	1.45e-46	-	-	-	-	-	-	-	-
HKNGKOGP_01906	2.83e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKNGKOGP_01907	6.63e-233	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKNGKOGP_01908	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HKNGKOGP_01909	1.01e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_01910	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HKNGKOGP_01911	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HKNGKOGP_01912	1.03e-212	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKNGKOGP_01913	3.05e-282	ysaA	-	-	V	-	-	-	RDD family
HKNGKOGP_01914	1.12e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HKNGKOGP_01915	2.8e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKNGKOGP_01916	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKNGKOGP_01917	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKNGKOGP_01918	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HKNGKOGP_01919	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKNGKOGP_01920	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKNGKOGP_01921	1.05e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKNGKOGP_01922	5.89e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKNGKOGP_01923	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HKNGKOGP_01924	1.34e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKNGKOGP_01925	1.74e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKNGKOGP_01926	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HKNGKOGP_01927	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HKNGKOGP_01928	2.4e-56	-	-	-	S	-	-	-	ankyrin repeats
HKNGKOGP_01929	5.3e-49	-	-	-	-	-	-	-	-
HKNGKOGP_01930	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKNGKOGP_01931	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKNGKOGP_01932	1.1e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKNGKOGP_01933	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKNGKOGP_01934	1.15e-235	-	-	-	S	-	-	-	DUF218 domain
HKNGKOGP_01935	7.12e-178	-	-	-	-	-	-	-	-
HKNGKOGP_01936	4.15e-191	yxeH	-	-	S	-	-	-	hydrolase
HKNGKOGP_01937	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HKNGKOGP_01938	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HKNGKOGP_01939	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKNGKOGP_01940	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKNGKOGP_01941	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKNGKOGP_01942	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKNGKOGP_01943	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HKNGKOGP_01944	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HKNGKOGP_01945	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKNGKOGP_01946	1.89e-169	-	-	-	S	-	-	-	YheO-like PAS domain
HKNGKOGP_01947	2.41e-37	-	-	-	-	-	-	-	-
HKNGKOGP_01948	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKNGKOGP_01949	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKNGKOGP_01950	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKNGKOGP_01951	1.49e-273	-	-	-	J	-	-	-	translation release factor activity
HKNGKOGP_01952	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HKNGKOGP_01953	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKNGKOGP_01954	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKNGKOGP_01955	1.84e-189	-	-	-	-	-	-	-	-
HKNGKOGP_01956	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKNGKOGP_01957	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKNGKOGP_01958	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_01959	1.49e-252	-	-	-	M	-	-	-	MucBP domain
HKNGKOGP_01960	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_01961	7.2e-41	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKNGKOGP_01962	1.06e-113	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKNGKOGP_01963	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HKNGKOGP_01964	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_01965	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKNGKOGP_01966	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKNGKOGP_01967	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKNGKOGP_01968	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKNGKOGP_01969	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKNGKOGP_01970	2.5e-132	-	-	-	L	-	-	-	Integrase
HKNGKOGP_01971	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKNGKOGP_01972	5.24e-28	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKNGKOGP_01973	5.6e-41	-	-	-	-	-	-	-	-
HKNGKOGP_01974	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HKNGKOGP_01975	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKNGKOGP_01976	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKNGKOGP_01977	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKNGKOGP_01978	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKNGKOGP_01979	1.88e-291	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKNGKOGP_01980	1.22e-292	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKNGKOGP_01981	5.63e-30	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HKNGKOGP_01982	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKNGKOGP_01994	5.4e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HKNGKOGP_01995	4.48e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HKNGKOGP_01996	2.07e-123	-	-	-	-	-	-	-	-
HKNGKOGP_01997	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_01998	1.7e-199	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKNGKOGP_02000	6.5e-279	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKNGKOGP_02001	2.08e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKNGKOGP_02002	2.01e-276	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKNGKOGP_02003	3.91e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HKNGKOGP_02004	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKNGKOGP_02005	5.79e-158	-	-	-	-	-	-	-	-
HKNGKOGP_02006	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKNGKOGP_02007	6.99e-281	mdr	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_02008	1.38e-57	mdr	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_02012	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HKNGKOGP_02013	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKNGKOGP_02014	1.58e-283	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKNGKOGP_02015	1.78e-159	-	-	-	S	-	-	-	YjbR
HKNGKOGP_02017	4.09e-42	cadA	-	-	P	-	-	-	P-type ATPase
HKNGKOGP_02018	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HKNGKOGP_02019	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HKNGKOGP_02020	1.46e-154	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKNGKOGP_02021	4.29e-101	-	-	-	-	-	-	-	-
HKNGKOGP_02022	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKNGKOGP_02023	5.71e-126	-	-	-	FG	-	-	-	HIT domain
HKNGKOGP_02024	7.39e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKNGKOGP_02025	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HKNGKOGP_02026	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKNGKOGP_02027	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKNGKOGP_02028	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
HKNGKOGP_02029	1.25e-123	-	-	-	V	-	-	-	VanZ like family
HKNGKOGP_02032	6.6e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKNGKOGP_02033	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKNGKOGP_02034	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HKNGKOGP_02035	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HKNGKOGP_02036	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKNGKOGP_02037	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02038	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKNGKOGP_02039	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKNGKOGP_02040	2.05e-153	-	-	-	I	-	-	-	phosphatase
HKNGKOGP_02041	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKNGKOGP_02042	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKNGKOGP_02043	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKNGKOGP_02044	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKNGKOGP_02045	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HKNGKOGP_02046	1.36e-77	-	-	-	-	-	-	-	-
HKNGKOGP_02047	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKNGKOGP_02048	6.24e-223	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKNGKOGP_02049	4.01e-95	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKNGKOGP_02050	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKNGKOGP_02051	1.46e-170	-	-	-	-	-	-	-	-
HKNGKOGP_02052	3.8e-128	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKNGKOGP_02053	1.57e-33	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKNGKOGP_02054	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02055	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKNGKOGP_02056	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HKNGKOGP_02057	5.41e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKNGKOGP_02058	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HKNGKOGP_02059	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKNGKOGP_02060	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HKNGKOGP_02061	2.96e-70	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKNGKOGP_02062	5.35e-60	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKNGKOGP_02063	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKNGKOGP_02064	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKNGKOGP_02065	1.18e-183	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKNGKOGP_02066	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKNGKOGP_02067	1.7e-190	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HKNGKOGP_02068	4.14e-61	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HKNGKOGP_02069	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKNGKOGP_02070	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKNGKOGP_02071	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKNGKOGP_02072	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKNGKOGP_02073	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKNGKOGP_02074	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HKNGKOGP_02075	2.82e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKNGKOGP_02076	6.4e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKNGKOGP_02077	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKNGKOGP_02078	3.95e-288	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HKNGKOGP_02079	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKNGKOGP_02080	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HKNGKOGP_02081	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKNGKOGP_02082	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKNGKOGP_02083	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
HKNGKOGP_02084	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HKNGKOGP_02085	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKNGKOGP_02086	1.34e-52	-	-	-	-	-	-	-	-
HKNGKOGP_02087	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HKNGKOGP_02088	1.91e-259	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKNGKOGP_02089	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKNGKOGP_02090	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HKNGKOGP_02091	4.96e-117	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKNGKOGP_02092	8.35e-119	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKNGKOGP_02093	4.68e-165	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKNGKOGP_02094	1.33e-54	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKNGKOGP_02095	2.28e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKNGKOGP_02096	5.3e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKNGKOGP_02097	1.01e-163	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKNGKOGP_02098	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKNGKOGP_02099	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_02100	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKNGKOGP_02101	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HKNGKOGP_02102	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKNGKOGP_02103	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKNGKOGP_02104	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKNGKOGP_02105	1.58e-39	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKNGKOGP_02106	6.84e-176	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKNGKOGP_02107	4.74e-94	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKNGKOGP_02108	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKNGKOGP_02109	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKNGKOGP_02110	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKNGKOGP_02111	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKNGKOGP_02112	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKNGKOGP_02113	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKNGKOGP_02114	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKNGKOGP_02115	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKNGKOGP_02116	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKNGKOGP_02117	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HKNGKOGP_02118	2.03e-110	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKNGKOGP_02119	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKNGKOGP_02120	4.39e-244	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKNGKOGP_02121	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKNGKOGP_02122	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKNGKOGP_02123	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKNGKOGP_02124	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HKNGKOGP_02125	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HKNGKOGP_02126	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKNGKOGP_02127	1.12e-246	ampC	-	-	V	-	-	-	Beta-lactamase
HKNGKOGP_02128	8.57e-41	-	-	-	-	-	-	-	-
HKNGKOGP_02129	1.26e-199	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HKNGKOGP_02130	1.33e-77	-	-	-	-	-	-	-	-
HKNGKOGP_02131	5.37e-182	-	-	-	-	-	-	-	-
HKNGKOGP_02132	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKNGKOGP_02133	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02134	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKNGKOGP_02135	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HKNGKOGP_02138	8.98e-54	-	-	-	S	-	-	-	Bacteriophage holin
HKNGKOGP_02139	9.2e-64	-	-	-	-	-	-	-	-
HKNGKOGP_02140	7.74e-244	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKNGKOGP_02141	1.18e-33	-	-	-	-	-	-	-	-
HKNGKOGP_02142	7.01e-108	-	-	-	-	-	-	-	-
HKNGKOGP_02145	2.31e-303	-	-	-	-	-	-	-	-
HKNGKOGP_02146	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HKNGKOGP_02147	1.36e-284	-	-	-	S	-	-	-	Phage tail protein
HKNGKOGP_02148	0.0	-	-	-	D	-	-	-	domain protein
HKNGKOGP_02149	3.69e-33	-	-	-	-	-	-	-	-
HKNGKOGP_02150	3.88e-75	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HKNGKOGP_02151	1.42e-138	-	-	-	S	-	-	-	Phage tail tube protein
HKNGKOGP_02152	7.78e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HKNGKOGP_02153	6.72e-88	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HKNGKOGP_02154	1.11e-72	-	-	-	S	-	-	-	Phage head-tail joining protein
HKNGKOGP_02155	5.64e-66	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKNGKOGP_02156	7.01e-270	-	-	-	S	-	-	-	Phage capsid family
HKNGKOGP_02157	1.68e-157	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HKNGKOGP_02158	1.03e-271	-	-	-	S	-	-	-	Phage portal protein
HKNGKOGP_02159	1.35e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HKNGKOGP_02160	0.0	-	-	-	S	-	-	-	Phage Terminase
HKNGKOGP_02161	7.49e-102	-	-	-	S	-	-	-	Phage terminase, small subunit
HKNGKOGP_02163	1.46e-117	-	-	-	L	-	-	-	HNH nucleases
HKNGKOGP_02164	1.43e-17	-	-	-	V	-	-	-	HNH nucleases
HKNGKOGP_02169	3.36e-27	-	-	-	-	-	-	-	-
HKNGKOGP_02170	9.31e-84	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HKNGKOGP_02175	2.12e-59	-	-	-	-	-	-	-	-
HKNGKOGP_02177	1.97e-185	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HKNGKOGP_02178	3.09e-93	-	-	-	L	-	-	-	DnaD domain protein
HKNGKOGP_02179	8.74e-169	-	-	-	S	-	-	-	Putative HNHc nuclease
HKNGKOGP_02190	9.15e-77	-	-	-	S	-	-	-	ORF6C domain
HKNGKOGP_02192	3.49e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKNGKOGP_02193	6.22e-48	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HKNGKOGP_02198	1.68e-60	-	-	-	L	-	-	-	Pfam:Integrase_AP2
HKNGKOGP_02200	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKNGKOGP_02201	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HKNGKOGP_02202	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKNGKOGP_02203	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HKNGKOGP_02204	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKNGKOGP_02205	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
HKNGKOGP_02206	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_02207	2.88e-306	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_02208	7.13e-195	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKNGKOGP_02209	2.55e-226	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKNGKOGP_02210	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_02211	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKNGKOGP_02212	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HKNGKOGP_02213	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKNGKOGP_02214	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKNGKOGP_02215	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKNGKOGP_02216	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
HKNGKOGP_02217	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKNGKOGP_02218	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKNGKOGP_02219	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKNGKOGP_02220	2.67e-119	yebE	-	-	S	-	-	-	UPF0316 protein
HKNGKOGP_02221	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKNGKOGP_02222	5.9e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HKNGKOGP_02223	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKNGKOGP_02224	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKNGKOGP_02225	4.57e-71	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKNGKOGP_02226	1.32e-57	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKNGKOGP_02227	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKNGKOGP_02228	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKNGKOGP_02229	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKNGKOGP_02230	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HKNGKOGP_02231	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKNGKOGP_02232	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HKNGKOGP_02233	6.07e-33	-	-	-	-	-	-	-	-
HKNGKOGP_02234	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKNGKOGP_02235	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKNGKOGP_02236	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HKNGKOGP_02237	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HKNGKOGP_02238	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HKNGKOGP_02239	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HKNGKOGP_02240	8.08e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKNGKOGP_02241	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKNGKOGP_02242	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKNGKOGP_02245	7.79e-13	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKNGKOGP_02246	4.15e-87	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKNGKOGP_02248	4.08e-26	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HKNGKOGP_02250	1.56e-78	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKNGKOGP_02251	5.59e-13	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family 2
HKNGKOGP_02252	1.54e-54	-	-	-	S	-	-	-	Glycosyl transferase family 2
HKNGKOGP_02253	3.07e-91	-	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HKNGKOGP_02254	2.93e-33	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HKNGKOGP_02255	2.13e-63	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HKNGKOGP_02256	1.5e-20	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
HKNGKOGP_02257	7.56e-197	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKNGKOGP_02258	1.39e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKNGKOGP_02259	3.23e-139	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKNGKOGP_02260	1.99e-183	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKNGKOGP_02261	2.88e-200	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
HKNGKOGP_02262	4.48e-110	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HKNGKOGP_02263	1.87e-172	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKNGKOGP_02264	1.95e-162	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKNGKOGP_02265	1.2e-165	epsB	-	-	M	-	-	-	biosynthesis protein
HKNGKOGP_02266	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HKNGKOGP_02267	1.22e-126	-	-	-	C	-	-	-	Nitroreductase family
HKNGKOGP_02268	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HKNGKOGP_02269	3.45e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKNGKOGP_02270	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKNGKOGP_02271	1.22e-200	ccpB	-	-	K	-	-	-	lacI family
HKNGKOGP_02272	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKNGKOGP_02273	1.18e-225	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKNGKOGP_02274	1.89e-254	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HKNGKOGP_02275	5.88e-224	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKNGKOGP_02276	5.46e-176	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKNGKOGP_02277	1.54e-185	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKNGKOGP_02278	1.19e-215	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKNGKOGP_02279	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HKNGKOGP_02280	2.66e-172	-	-	-	-	-	-	-	-
HKNGKOGP_02281	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_02282	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HKNGKOGP_02283	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HKNGKOGP_02284	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HKNGKOGP_02285	3.25e-161	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKNGKOGP_02286	9.01e-155	-	-	-	S	-	-	-	Membrane
HKNGKOGP_02287	1.97e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKNGKOGP_02288	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HKNGKOGP_02289	2e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKNGKOGP_02290	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HKNGKOGP_02291	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02292	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKNGKOGP_02293	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HKNGKOGP_02294	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKNGKOGP_02295	9.38e-189	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_02296	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKNGKOGP_02297	3.46e-251	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKNGKOGP_02298	4.35e-164	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKNGKOGP_02299	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKNGKOGP_02300	5.97e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKNGKOGP_02301	4.45e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKNGKOGP_02302	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKNGKOGP_02303	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HKNGKOGP_02304	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKNGKOGP_02305	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKNGKOGP_02307	6.74e-52	-	-	-	M	-	-	-	LysM domain
HKNGKOGP_02308	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HKNGKOGP_02310	1.08e-208	-	-	-	-	-	-	-	-
HKNGKOGP_02311	2.76e-28	-	-	-	S	-	-	-	Cell surface protein
HKNGKOGP_02314	2.03e-12	-	-	-	L	-	-	-	Helix-turn-helix domain
HKNGKOGP_02315	4.32e-16	-	-	-	L	-	-	-	Helix-turn-helix domain
HKNGKOGP_02316	2.28e-22	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_02317	2.15e-17	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKNGKOGP_02319	3.07e-06	-	-	-	D	-	-	-	Mycoplasma protein of unknown function, DUF285
HKNGKOGP_02321	2.72e-70	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKNGKOGP_02323	2.12e-27	-	-	-	L	ko:K07487	-	ko00000	Transposase
HKNGKOGP_02324	9.07e-22	-	-	-	L	ko:K07487	-	ko00000	Transposase
HKNGKOGP_02325	7.48e-11	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKNGKOGP_02326	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HKNGKOGP_02327	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKNGKOGP_02328	2.19e-144	-	-	-	-	-	-	-	-
HKNGKOGP_02329	2.94e-227	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKNGKOGP_02330	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
HKNGKOGP_02331	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKNGKOGP_02332	1.81e-119	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKNGKOGP_02333	2.77e-77	-	-	-	-	-	-	-	-
HKNGKOGP_02334	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKNGKOGP_02335	5.09e-55	-	-	-	-	-	-	-	-
HKNGKOGP_02336	3.72e-21	-	-	-	-	-	-	-	-
HKNGKOGP_02338	3.22e-140	-	-	-	L	-	-	-	Integrase
HKNGKOGP_02339	1.54e-30	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
HKNGKOGP_02340	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKNGKOGP_02341	2.29e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKNGKOGP_02342	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HKNGKOGP_02343	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02344	1.86e-210	-	-	-	-	-	-	-	-
HKNGKOGP_02345	1.23e-75	-	-	-	-	-	-	-	-
HKNGKOGP_02346	1.13e-54	-	-	-	-	-	-	-	-
HKNGKOGP_02347	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HKNGKOGP_02348	3.65e-59	-	-	-	S	-	-	-	Cupredoxin-like domain
HKNGKOGP_02349	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKNGKOGP_02350	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HKNGKOGP_02353	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HKNGKOGP_02354	8.11e-278	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKNGKOGP_02355	3.71e-98	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKNGKOGP_02356	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKNGKOGP_02357	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKNGKOGP_02358	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKNGKOGP_02360	1.25e-176	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNGKOGP_02361	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNGKOGP_02362	1.83e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKNGKOGP_02363	1.88e-250	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKNGKOGP_02364	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKNGKOGP_02365	4.8e-293	-	-	-	M	-	-	-	O-Antigen ligase
HKNGKOGP_02366	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKNGKOGP_02367	6.88e-140	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_02368	7.43e-49	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_02369	4.54e-111	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_02370	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HKNGKOGP_02371	1.94e-83	-	-	-	P	-	-	-	Rhodanese Homology Domain
HKNGKOGP_02372	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_02373	1.07e-263	-	-	-	-	-	-	-	-
HKNGKOGP_02374	6.08e-277	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKNGKOGP_02375	5.25e-233	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKNGKOGP_02376	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKNGKOGP_02377	4.44e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNGKOGP_02378	2.18e-305	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HKNGKOGP_02379	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02380	6.46e-265	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKNGKOGP_02381	1.39e-235	tanA	-	-	S	-	-	-	alpha beta
HKNGKOGP_02383	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKNGKOGP_02384	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKNGKOGP_02385	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKNGKOGP_02386	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HKNGKOGP_02387	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HKNGKOGP_02388	5.7e-146	-	-	-	GM	-	-	-	epimerase
HKNGKOGP_02389	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HKNGKOGP_02390	4.31e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_02391	1.12e-273	-	-	-	S	-	-	-	membrane
HKNGKOGP_02392	1.55e-07	-	-	-	K	-	-	-	transcriptional regulator
HKNGKOGP_02393	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_02394	8.34e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_02395	7.51e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HKNGKOGP_02396	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKNGKOGP_02397	3.69e-169	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKNGKOGP_02398	2.63e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HKNGKOGP_02399	3.55e-146	-	-	-	GM	-	-	-	NmrA-like family
HKNGKOGP_02400	2.12e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HKNGKOGP_02401	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02402	2.66e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKNGKOGP_02404	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKNGKOGP_02405	6.86e-78	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HKNGKOGP_02406	1.06e-39	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HKNGKOGP_02407	2.08e-265	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKNGKOGP_02408	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKNGKOGP_02409	3.43e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_02411	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKNGKOGP_02412	3.89e-94	-	-	-	K	-	-	-	MarR family
HKNGKOGP_02413	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKNGKOGP_02414	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKNGKOGP_02415	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02416	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKNGKOGP_02417	2.48e-252	-	-	-	-	-	-	-	-
HKNGKOGP_02418	5.27e-15	-	-	-	-	-	-	-	-
HKNGKOGP_02419	1.56e-222	-	-	-	-	-	-	-	-
HKNGKOGP_02420	1.53e-142	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02421	1.04e-35	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02422	6.86e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKNGKOGP_02423	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKNGKOGP_02424	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKNGKOGP_02425	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKNGKOGP_02426	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKNGKOGP_02427	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKNGKOGP_02428	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKNGKOGP_02429	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HKNGKOGP_02430	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKNGKOGP_02431	9.71e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKNGKOGP_02432	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HKNGKOGP_02433	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKNGKOGP_02434	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKNGKOGP_02435	4.64e-143	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKNGKOGP_02436	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKNGKOGP_02437	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKNGKOGP_02438	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKNGKOGP_02439	2.15e-131	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKNGKOGP_02440	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKNGKOGP_02441	2.17e-51	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKNGKOGP_02442	2.85e-238	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKNGKOGP_02443	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HKNGKOGP_02444	2.65e-213	-	-	-	G	-	-	-	Fructosamine kinase
HKNGKOGP_02445	2.91e-64	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HKNGKOGP_02446	6.79e-43	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HKNGKOGP_02447	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKNGKOGP_02448	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKNGKOGP_02449	2.56e-76	-	-	-	-	-	-	-	-
HKNGKOGP_02450	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKNGKOGP_02451	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKNGKOGP_02452	1.68e-92	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKNGKOGP_02453	1.45e-29	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKNGKOGP_02454	4.78e-65	-	-	-	-	-	-	-	-
HKNGKOGP_02455	1.73e-67	-	-	-	-	-	-	-	-
HKNGKOGP_02456	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKNGKOGP_02457	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKNGKOGP_02458	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKNGKOGP_02459	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HKNGKOGP_02460	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKNGKOGP_02461	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKNGKOGP_02462	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HKNGKOGP_02463	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKNGKOGP_02464	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKNGKOGP_02465	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKNGKOGP_02466	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKNGKOGP_02467	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HKNGKOGP_02468	7.56e-242	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKNGKOGP_02469	6.29e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKNGKOGP_02470	1.45e-114	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKNGKOGP_02471	5.99e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HKNGKOGP_02472	6.72e-302	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKNGKOGP_02473	1.34e-120	-	-	-	-	-	-	-	-
HKNGKOGP_02474	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKNGKOGP_02475	0.0	-	-	-	G	-	-	-	Major Facilitator
HKNGKOGP_02476	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKNGKOGP_02477	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKNGKOGP_02478	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HKNGKOGP_02479	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HKNGKOGP_02480	1.43e-76	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKNGKOGP_02481	7.39e-171	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKNGKOGP_02482	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKNGKOGP_02483	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKNGKOGP_02484	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKNGKOGP_02485	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKNGKOGP_02486	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKNGKOGP_02487	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKNGKOGP_02488	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKNGKOGP_02489	1.49e-78	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKNGKOGP_02490	2.62e-50	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKNGKOGP_02491	1.55e-193	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKNGKOGP_02492	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKNGKOGP_02493	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HKNGKOGP_02494	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNGKOGP_02495	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HKNGKOGP_02496	3.65e-172	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HKNGKOGP_02497	1.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKNGKOGP_02498	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HKNGKOGP_02499	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HKNGKOGP_02500	3.42e-87	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKNGKOGP_02501	4.51e-50	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKNGKOGP_02502	1.83e-121	-	-	-	-	-	-	-	-
HKNGKOGP_02503	6.62e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HKNGKOGP_02504	1.01e-100	-	-	-	-	-	-	-	-
HKNGKOGP_02505	3.26e-88	-	-	-	-	-	-	-	-
HKNGKOGP_02506	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HKNGKOGP_02509	5.32e-12	-	-	-	S	-	-	-	Short C-terminal domain
HKNGKOGP_02510	1.79e-21	-	-	-	S	-	-	-	Short C-terminal domain
HKNGKOGP_02511	5.48e-05	-	-	-	S	-	-	-	Short C-terminal domain
HKNGKOGP_02513	1.3e-53	-	-	-	-	-	-	-	-
HKNGKOGP_02515	1.15e-315	-	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_02516	4.21e-141	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HKNGKOGP_02517	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKNGKOGP_02519	3.33e-27	-	-	-	M	-	-	-	domain protein
HKNGKOGP_02520	4.04e-62	-	-	-	M	-	-	-	domain protein
HKNGKOGP_02521	3.88e-20	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKNGKOGP_02529	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02530	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKNGKOGP_02531	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HKNGKOGP_02532	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKNGKOGP_02533	0.0	ycaM	-	-	E	-	-	-	amino acid
HKNGKOGP_02534	2.89e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HKNGKOGP_02535	4.3e-44	-	-	-	-	-	-	-	-
HKNGKOGP_02536	2.85e-147	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HKNGKOGP_02537	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKNGKOGP_02538	4.12e-50	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKNGKOGP_02539	4.52e-79	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKNGKOGP_02540	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HKNGKOGP_02541	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKNGKOGP_02542	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKNGKOGP_02543	9.38e-97	-	-	-	EG	-	-	-	EamA-like transporter family
HKNGKOGP_02544	1.11e-80	-	-	-	EG	-	-	-	EamA-like transporter family
HKNGKOGP_02545	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKNGKOGP_02546	5.06e-196	-	-	-	S	-	-	-	hydrolase
HKNGKOGP_02547	7.63e-107	-	-	-	-	-	-	-	-
HKNGKOGP_02548	1.21e-129	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HKNGKOGP_02549	0.000999	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HKNGKOGP_02550	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HKNGKOGP_02551	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKNGKOGP_02552	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKNGKOGP_02553	2.73e-73	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HKNGKOGP_02554	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_02555	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKNGKOGP_02556	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HKNGKOGP_02557	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKNGKOGP_02558	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_02559	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02560	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKNGKOGP_02561	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HKNGKOGP_02562	2.12e-234	-	-	-	S	-	-	-	Sterol carrier protein domain
HKNGKOGP_02563	8.6e-14	-	-	-	S	-	-	-	Sterol carrier protein domain
HKNGKOGP_02564	2.57e-222	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKNGKOGP_02565	1.84e-26	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKNGKOGP_02566	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HKNGKOGP_02567	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKNGKOGP_02568	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HKNGKOGP_02569	5.38e-131	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HKNGKOGP_02570	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKNGKOGP_02571	2.38e-37	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HKNGKOGP_02572	1.1e-184	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKNGKOGP_02573	6.51e-179	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKNGKOGP_02574	1.65e-145	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKNGKOGP_02575	5.45e-64	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKNGKOGP_02576	1.11e-298	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKNGKOGP_02577	1.21e-69	-	-	-	-	-	-	-	-
HKNGKOGP_02578	1.52e-151	-	-	-	-	-	-	-	-
HKNGKOGP_02579	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HKNGKOGP_02580	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKNGKOGP_02581	4.79e-13	-	-	-	-	-	-	-	-
HKNGKOGP_02582	1.4e-65	-	-	-	-	-	-	-	-
HKNGKOGP_02583	1.76e-114	-	-	-	-	-	-	-	-
HKNGKOGP_02584	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKNGKOGP_02585	1.08e-47	-	-	-	-	-	-	-	-
HKNGKOGP_02586	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HKNGKOGP_02587	5.66e-189	-	-	-	-	-	-	-	-
HKNGKOGP_02588	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02589	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HKNGKOGP_02590	4.76e-56	-	-	-	-	-	-	-	-
HKNGKOGP_02591	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKNGKOGP_02592	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02593	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HKNGKOGP_02594	9.78e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_02595	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HKNGKOGP_02596	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKNGKOGP_02597	5.76e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HKNGKOGP_02598	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKNGKOGP_02599	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HKNGKOGP_02600	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKNGKOGP_02601	5.8e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKNGKOGP_02602	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKNGKOGP_02603	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKNGKOGP_02604	5.68e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKNGKOGP_02605	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKNGKOGP_02606	1.48e-208	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKNGKOGP_02607	2.85e-94	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKNGKOGP_02608	1.04e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKNGKOGP_02609	1.79e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKNGKOGP_02610	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKNGKOGP_02611	6.66e-281	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKNGKOGP_02612	3.85e-159	-	-	-	E	-	-	-	Methionine synthase
HKNGKOGP_02613	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HKNGKOGP_02614	1.85e-121	-	-	-	-	-	-	-	-
HKNGKOGP_02615	1.25e-199	-	-	-	T	-	-	-	EAL domain
HKNGKOGP_02616	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
HKNGKOGP_02617	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HKNGKOGP_02618	9.44e-185	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKNGKOGP_02619	4.91e-89	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKNGKOGP_02620	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HKNGKOGP_02621	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKNGKOGP_02622	1.42e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKNGKOGP_02623	7.96e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKNGKOGP_02624	4.77e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKNGKOGP_02625	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKNGKOGP_02626	4.24e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKNGKOGP_02627	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKNGKOGP_02628	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKNGKOGP_02629	4.54e-216	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HKNGKOGP_02630	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKNGKOGP_02631	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKNGKOGP_02632	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKNGKOGP_02633	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_02634	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HKNGKOGP_02635	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKNGKOGP_02636	3.59e-26	-	-	-	-	-	-	-	-
HKNGKOGP_02637	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKNGKOGP_02638	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKNGKOGP_02639	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HKNGKOGP_02640	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKNGKOGP_02641	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKNGKOGP_02642	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKNGKOGP_02643	8.13e-82	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_02644	5.57e-269	yttB	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_02645	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKNGKOGP_02646	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HKNGKOGP_02647	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HKNGKOGP_02648	2.97e-76	-	-	-	-	-	-	-	-
HKNGKOGP_02649	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKNGKOGP_02650	6.46e-52	-	-	-	-	-	-	-	-
HKNGKOGP_02651	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKNGKOGP_02652	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HKNGKOGP_02653	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNGKOGP_02654	1.18e-176	-	-	-	-	-	-	-	-
HKNGKOGP_02655	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKNGKOGP_02656	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02657	2.25e-206	-	-	-	S	-	-	-	Putative esterase
HKNGKOGP_02658	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKNGKOGP_02659	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKNGKOGP_02660	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKNGKOGP_02661	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKNGKOGP_02662	9.66e-97	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKNGKOGP_02663	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HKNGKOGP_02664	2.73e-24	-	-	-	-	-	-	-	-
HKNGKOGP_02665	8.36e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKNGKOGP_02666	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
HKNGKOGP_02667	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HKNGKOGP_02668	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HKNGKOGP_02669	4.15e-78	-	-	-	-	-	-	-	-
HKNGKOGP_02670	4.05e-98	-	-	-	-	-	-	-	-
HKNGKOGP_02671	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HKNGKOGP_02672	2.16e-63	-	-	-	-	-	-	-	-
HKNGKOGP_02673	3.89e-62	-	-	-	-	-	-	-	-
HKNGKOGP_02674	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKNGKOGP_02675	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HKNGKOGP_02676	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HKNGKOGP_02677	4.27e-89	-	-	-	-	-	-	-	-
HKNGKOGP_02678	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKNGKOGP_02679	1.7e-67	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKNGKOGP_02680	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKNGKOGP_02681	4.13e-182	-	-	-	-	-	-	-	-
HKNGKOGP_02683	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HKNGKOGP_02684	3.88e-46	-	-	-	-	-	-	-	-
HKNGKOGP_02685	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HKNGKOGP_02686	7.85e-212	-	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_02687	2.23e-77	-	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_02688	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKNGKOGP_02689	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKNGKOGP_02690	1.14e-91	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKNGKOGP_02691	4.43e-253	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKNGKOGP_02692	5.43e-31	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HKNGKOGP_02693	2.59e-152	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HKNGKOGP_02694	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02695	1.36e-27	-	-	-	-	-	-	-	-
HKNGKOGP_02696	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKNGKOGP_02697	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKNGKOGP_02698	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKNGKOGP_02699	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKNGKOGP_02700	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKNGKOGP_02701	2.4e-201	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKNGKOGP_02702	3.17e-83	oatA	-	-	I	-	-	-	Acyltransferase
HKNGKOGP_02703	2.26e-273	oatA	-	-	I	-	-	-	Acyltransferase
HKNGKOGP_02704	2.61e-123	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKNGKOGP_02705	3.66e-63	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKNGKOGP_02706	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKNGKOGP_02707	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HKNGKOGP_02708	1.09e-60	-	-	-	-	-	-	-	-
HKNGKOGP_02709	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKNGKOGP_02710	2.66e-05	-	-	-	-	-	-	-	-
HKNGKOGP_02711	8.82e-69	-	-	-	-	-	-	-	-
HKNGKOGP_02712	7.76e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKNGKOGP_02713	3.05e-95	-	-	-	F	-	-	-	Nudix hydrolase
HKNGKOGP_02714	1.48e-27	-	-	-	-	-	-	-	-
HKNGKOGP_02715	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HKNGKOGP_02716	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HKNGKOGP_02717	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HKNGKOGP_02718	1.01e-188	-	-	-	-	-	-	-	-
HKNGKOGP_02719	1.28e-134	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HKNGKOGP_02720	1.86e-267	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKNGKOGP_02721	5.1e-218	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNGKOGP_02722	1.28e-54	-	-	-	-	-	-	-	-
HKNGKOGP_02724	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02725	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKNGKOGP_02726	1.81e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_02727	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKNGKOGP_02728	1e-107	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKNGKOGP_02729	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKNGKOGP_02730	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKNGKOGP_02731	1.24e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HKNGKOGP_02732	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKNGKOGP_02733	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_02734	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HKNGKOGP_02735	3.08e-93	-	-	-	K	-	-	-	MarR family
HKNGKOGP_02736	6.5e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKNGKOGP_02737	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKNGKOGP_02738	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_02739	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKNGKOGP_02740	1.88e-101	rppH3	-	-	F	-	-	-	NUDIX domain
HKNGKOGP_02741	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HKNGKOGP_02742	1.61e-36	-	-	-	-	-	-	-	-
HKNGKOGP_02743	5.48e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HKNGKOGP_02744	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HKNGKOGP_02745	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HKNGKOGP_02746	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HKNGKOGP_02747	2.84e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HKNGKOGP_02748	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKNGKOGP_02749	3.59e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HKNGKOGP_02750	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKNGKOGP_02751	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKNGKOGP_02753	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
HKNGKOGP_02755	9.16e-61	-	-	-	L	-	-	-	Helix-turn-helix domain
HKNGKOGP_02756	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKNGKOGP_02757	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKNGKOGP_02758	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKNGKOGP_02759	4.16e-97	-	-	-	-	-	-	-	-
HKNGKOGP_02760	1.08e-71	-	-	-	-	-	-	-	-
HKNGKOGP_02761	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_02762	1.16e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_02763	3.08e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKNGKOGP_02764	1.92e-301	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
HKNGKOGP_02765	1.17e-284	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HKNGKOGP_02766	3.61e-61	-	-	-	S	-	-	-	MORN repeat
HKNGKOGP_02767	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HKNGKOGP_02768	1.08e-25	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HKNGKOGP_02769	1.95e-116	-	-	-	-	-	-	-	-
HKNGKOGP_02770	5.74e-32	-	-	-	-	-	-	-	-
HKNGKOGP_02771	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKNGKOGP_02772	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKNGKOGP_02773	3.38e-19	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HKNGKOGP_02774	1.57e-142	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HKNGKOGP_02775	4.25e-211	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKNGKOGP_02776	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKNGKOGP_02777	2.19e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
HKNGKOGP_02778	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKNGKOGP_02779	3.04e-111	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKNGKOGP_02780	1.5e-285	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKNGKOGP_02781	3.37e-60	-	-	-	S	-	-	-	MazG-like family
HKNGKOGP_02782	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HKNGKOGP_02783	0.0	-	-	-	M	-	-	-	MucBP domain
HKNGKOGP_02784	1.42e-08	-	-	-	-	-	-	-	-
HKNGKOGP_02785	8.19e-81	-	-	-	S	-	-	-	AAA domain
HKNGKOGP_02786	1.06e-179	-	-	-	K	-	-	-	sequence-specific DNA binding
HKNGKOGP_02787	1.88e-124	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_02788	1.37e-220	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02789	0.0	-	-	-	C	-	-	-	FMN_bind
HKNGKOGP_02791	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02792	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKNGKOGP_02793	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKNGKOGP_02794	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HKNGKOGP_02795	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKNGKOGP_02796	3.79e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKNGKOGP_02797	5.44e-56	-	-	-	-	-	-	-	-
HKNGKOGP_02798	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HKNGKOGP_02799	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKNGKOGP_02800	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKNGKOGP_02801	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKNGKOGP_02802	4.34e-135	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKNGKOGP_02803	1.12e-243	-	-	-	-	-	-	-	-
HKNGKOGP_02804	3.46e-238	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKNGKOGP_02805	2.39e-26	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKNGKOGP_02806	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HKNGKOGP_02807	4.77e-130	-	-	-	K	-	-	-	FR47-like protein
HKNGKOGP_02808	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HKNGKOGP_02809	3.33e-64	-	-	-	-	-	-	-	-
HKNGKOGP_02810	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKNGKOGP_02811	0.0	xylP2	-	-	G	-	-	-	symporter
HKNGKOGP_02812	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKNGKOGP_02813	2.97e-220	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKNGKOGP_02814	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKNGKOGP_02815	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HKNGKOGP_02816	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HKNGKOGP_02817	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKNGKOGP_02824	2.26e-123	-	-	-	P	-	-	-	Cadmium resistance transporter
HKNGKOGP_02825	3.36e-62	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HKNGKOGP_02826	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKNGKOGP_02827	7.03e-62	-	-	-	-	-	-	-	-
HKNGKOGP_02828	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKNGKOGP_02829	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKNGKOGP_02830	3.52e-66	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKNGKOGP_02831	3.43e-73	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKNGKOGP_02832	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HKNGKOGP_02833	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKNGKOGP_02834	1.15e-43	-	-	-	-	-	-	-	-
HKNGKOGP_02836	1.66e-256	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKNGKOGP_02837	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKNGKOGP_02838	3.79e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKNGKOGP_02839	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HKNGKOGP_02840	1.61e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_02841	3.02e-47	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HKNGKOGP_02842	6.08e-71	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HKNGKOGP_02843	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKNGKOGP_02844	7.52e-240	-	-	-	S	-	-	-	Cell surface protein
HKNGKOGP_02845	3.08e-80	-	-	-	-	-	-	-	-
HKNGKOGP_02846	0.0	-	-	-	-	-	-	-	-
HKNGKOGP_02847	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_02848	2.76e-196	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKNGKOGP_02849	7.52e-139	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKNGKOGP_02850	9.55e-41	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKNGKOGP_02851	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKNGKOGP_02852	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
HKNGKOGP_02853	6.37e-125	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKNGKOGP_02854	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HKNGKOGP_02855	9.16e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKNGKOGP_02856	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKNGKOGP_02857	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HKNGKOGP_02858	2.39e-225	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HKNGKOGP_02859	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKNGKOGP_02860	6.92e-206	yicL	-	-	EG	-	-	-	EamA-like transporter family
HKNGKOGP_02861	5.17e-297	-	-	-	M	-	-	-	Collagen binding domain
HKNGKOGP_02862	0.0	-	-	-	I	-	-	-	acetylesterase activity
HKNGKOGP_02863	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HKNGKOGP_02864	2.29e-175	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HKNGKOGP_02865	4.29e-50	-	-	-	-	-	-	-	-
HKNGKOGP_02867	2.79e-184	-	-	-	S	-	-	-	zinc-ribbon domain
HKNGKOGP_02868	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKNGKOGP_02869	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HKNGKOGP_02870	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HKNGKOGP_02871	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_02872	1.19e-59	-	-	-	-	-	-	-	-
HKNGKOGP_02873	5.28e-74	-	-	-	-	-	-	-	-
HKNGKOGP_02874	3.7e-30	-	-	-	-	-	-	-	-
HKNGKOGP_02875	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKNGKOGP_02876	1.59e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNGKOGP_02877	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKNGKOGP_02878	1.56e-108	-	-	-	-	-	-	-	-
HKNGKOGP_02879	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKNGKOGP_02880	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKNGKOGP_02881	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKNGKOGP_02882	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HKNGKOGP_02883	3.54e-117	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKNGKOGP_02884	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HKNGKOGP_02885	7.76e-295	-	-	-	-	-	-	-	-
HKNGKOGP_02886	4.82e-54	-	-	-	-	-	-	-	-
HKNGKOGP_02887	1.01e-167	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKNGKOGP_02888	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKNGKOGP_02889	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HKNGKOGP_02890	2.65e-74	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HKNGKOGP_02891	2.64e-190	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HKNGKOGP_02892	2.67e-220	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKNGKOGP_02893	2.33e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKNGKOGP_02894	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HKNGKOGP_02895	5.28e-67	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKNGKOGP_02896	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKNGKOGP_02897	1.1e-188	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKNGKOGP_02898	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKNGKOGP_02899	9.53e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_02900	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKNGKOGP_02901	1.06e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_02902	3.34e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKNGKOGP_02903	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKNGKOGP_02904	1.74e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HKNGKOGP_02905	1.58e-230	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HKNGKOGP_02908	9.09e-314	-	-	-	EGP	-	-	-	Major Facilitator
HKNGKOGP_02909	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_02910	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_02912	4.96e-247	-	-	-	C	-	-	-	Aldo/keto reductase family
HKNGKOGP_02913	1.52e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HKNGKOGP_02914	3.45e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKNGKOGP_02915	6.36e-19	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKNGKOGP_02916	2.19e-97	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKNGKOGP_02917	1.12e-105	-	-	-	-	-	-	-	-
HKNGKOGP_02918	1.19e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKNGKOGP_02919	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKNGKOGP_02920	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKNGKOGP_02921	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_02922	3.08e-178	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HKNGKOGP_02923	4.02e-181	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKNGKOGP_02924	2.41e-165	-	-	-	C	-	-	-	Aldo keto reductase
HKNGKOGP_02925	9.99e-147	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_02926	2.83e-27	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKNGKOGP_02927	1.03e-31	-	-	-	C	-	-	-	Flavodoxin
HKNGKOGP_02929	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
HKNGKOGP_02930	2.11e-132	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKNGKOGP_02931	7.8e-113	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_02932	1.43e-114	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKNGKOGP_02933	2.78e-160	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
HKNGKOGP_02934	2.14e-98	-	-	-	C	-	-	-	Flavodoxin
HKNGKOGP_02935	4.83e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKNGKOGP_02936	1.2e-181	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKNGKOGP_02937	5.85e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKNGKOGP_02938	2.03e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKNGKOGP_02939	7.24e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
HKNGKOGP_02940	1.57e-202	-	-	-	K	-	-	-	LysR substrate binding domain
HKNGKOGP_02941	2.65e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HKNGKOGP_02942	5.46e-145	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HKNGKOGP_02943	2.81e-64	-	-	-	-	-	-	-	-
HKNGKOGP_02944	2.8e-49	-	-	-	-	-	-	-	-
HKNGKOGP_02945	5.14e-111	yvbK	-	-	K	-	-	-	GNAT family
HKNGKOGP_02946	2.82e-110	-	-	-	-	-	-	-	-
HKNGKOGP_02947	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKNGKOGP_02948	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKNGKOGP_02949	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKNGKOGP_02951	2.03e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02952	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKNGKOGP_02953	5.3e-302	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKNGKOGP_02954	7.37e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HKNGKOGP_02955	7.92e-99	yphH	-	-	S	-	-	-	Cupin domain
HKNGKOGP_02956	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKNGKOGP_02957	3.63e-165	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNGKOGP_02958	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKNGKOGP_02959	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02960	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKNGKOGP_02961	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02962	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKNGKOGP_02963	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKNGKOGP_02964	3.55e-62	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HKNGKOGP_02965	2.18e-123	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HKNGKOGP_02966	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HKNGKOGP_02967	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HKNGKOGP_02968	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKNGKOGP_02969	1.46e-239	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKNGKOGP_02970	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKNGKOGP_02971	9.2e-62	-	-	-	-	-	-	-	-
HKNGKOGP_02972	5.76e-107	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKNGKOGP_02973	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HKNGKOGP_02974	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKNGKOGP_02975	4.86e-279	-	-	-	T	-	-	-	diguanylate cyclase
HKNGKOGP_02976	1.11e-45	-	-	-	-	-	-	-	-
HKNGKOGP_02977	2.29e-48	-	-	-	-	-	-	-	-
HKNGKOGP_02978	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HKNGKOGP_02979	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HKNGKOGP_02980	9.53e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_02982	2.68e-32	-	-	-	-	-	-	-	-
HKNGKOGP_02983	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HKNGKOGP_02984	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HKNGKOGP_02985	1.31e-64	-	-	-	-	-	-	-	-
HKNGKOGP_02986	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKNGKOGP_02988	2.55e-218	-	-	-	EG	-	-	-	EamA-like transporter family
HKNGKOGP_02989	6.12e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HKNGKOGP_02990	5.76e-17	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKNGKOGP_02991	2.57e-279	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKNGKOGP_02992	1.39e-171	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HKNGKOGP_02993	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HKNGKOGP_02994	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HKNGKOGP_02995	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKNGKOGP_02996	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKNGKOGP_02997	2.1e-33	-	-	-	-	-	-	-	-
HKNGKOGP_02998	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_02999	3.12e-240	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKNGKOGP_03000	6.53e-84	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKNGKOGP_03001	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HKNGKOGP_03002	4.63e-24	-	-	-	-	-	-	-	-
HKNGKOGP_03003	2.16e-26	-	-	-	-	-	-	-	-
HKNGKOGP_03004	1.67e-13	-	-	-	-	-	-	-	-
HKNGKOGP_03005	1.56e-22	-	-	-	-	-	-	-	-
HKNGKOGP_03006	3.26e-24	-	-	-	-	-	-	-	-
HKNGKOGP_03007	6.58e-24	-	-	-	-	-	-	-	-
HKNGKOGP_03008	0.0	inlJ	-	-	M	-	-	-	MucBP domain
HKNGKOGP_03009	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HKNGKOGP_03010	1.27e-109	-	-	-	K	-	-	-	MarR family
HKNGKOGP_03011	9.28e-58	-	-	-	-	-	-	-	-
HKNGKOGP_03012	1.28e-51	-	-	-	-	-	-	-	-
HKNGKOGP_03014	1.98e-40	-	-	-	-	-	-	-	-
HKNGKOGP_03016	9.38e-279	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKNGKOGP_03017	1.01e-63	-	-	-	S	-	-	-	Domain of unknown function DUF1829
HKNGKOGP_03023	4.23e-19	-	-	-	S	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKNGKOGP_03026	7.9e-74	-	-	-	-	-	-	-	-
HKNGKOGP_03028	1.74e-108	-	-	-	-	-	-	-	-
HKNGKOGP_03029	2.73e-97	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HKNGKOGP_03030	2.67e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HKNGKOGP_03031	1.79e-36	-	-	-	K	-	-	-	Helix-turn-helix
HKNGKOGP_03035	1.19e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKNGKOGP_03036	2.62e-08	-	-	-	K	-	-	-	Transcriptional regulator, XRE family
HKNGKOGP_03039	7.71e-71	-	-	-	-	-	-	-	-
HKNGKOGP_03040	1.56e-103	-	-	-	-	-	-	-	-
HKNGKOGP_03042	1.75e-91	-	-	-	-	-	-	-	-
HKNGKOGP_03043	9.3e-193	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HKNGKOGP_03044	2.09e-171	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HKNGKOGP_03045	8.87e-199	-	-	-	L	-	-	-	DnaD domain protein
HKNGKOGP_03046	2.67e-66	-	-	-	-	-	-	-	-
HKNGKOGP_03047	1.83e-112	-	-	-	-	-	-	-	-
HKNGKOGP_03048	7.18e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HKNGKOGP_03050	3.86e-107	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
HKNGKOGP_03053	4.63e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HKNGKOGP_03054	1.54e-102	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HKNGKOGP_03055	8.83e-306	-	-	-	S	-	-	-	Terminase-like family
HKNGKOGP_03056	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HKNGKOGP_03057	4.98e-51	-	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HKNGKOGP_03058	0.0	-	-	-	S	-	-	-	Phage Mu protein F like protein
HKNGKOGP_03059	3.05e-41	-	-	-	-	-	-	-	-
HKNGKOGP_03062	5.72e-64	-	-	-	-	-	-	-	-
HKNGKOGP_03063	2.08e-222	-	-	-	S	-	-	-	Phage major capsid protein E
HKNGKOGP_03065	1.68e-67	-	-	-	-	-	-	-	-
HKNGKOGP_03066	9.63e-68	-	-	-	-	-	-	-	-
HKNGKOGP_03067	5.34e-115	-	-	-	-	-	-	-	-
HKNGKOGP_03068	3.49e-72	-	-	-	-	-	-	-	-
HKNGKOGP_03069	7.42e-102	-	-	-	S	-	-	-	Phage tail tube protein, TTP
HKNGKOGP_03070	1.42e-83	-	-	-	-	-	-	-	-
HKNGKOGP_03071	1.2e-264	-	-	-	D	-	-	-	domain protein
HKNGKOGP_03072	0.0	-	-	-	D	-	-	-	domain protein
HKNGKOGP_03073	9.32e-81	-	-	-	-	-	-	-	-
HKNGKOGP_03074	0.0	-	-	-	LM	-	-	-	DNA recombination
HKNGKOGP_03075	6.19e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1617)
HKNGKOGP_03077	7.37e-231	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKNGKOGP_03078	4.39e-62	-	-	-	-	-	-	-	-
HKNGKOGP_03079	2.46e-50	-	-	-	S	-	-	-	Bacteriophage holin
HKNGKOGP_03080	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HKNGKOGP_03081	5.22e-293	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNGKOGP_03082	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKNGKOGP_03084	7.62e-97	-	-	-	-	-	-	-	-
HKNGKOGP_03085	1.18e-138	-	-	-	-	-	-	-	-
HKNGKOGP_03086	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKNGKOGP_03087	4.68e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
HKNGKOGP_03088	1.12e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKNGKOGP_03089	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKNGKOGP_03090	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKNGKOGP_03091	2.4e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKNGKOGP_03092	1.81e-104	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HKNGKOGP_03093	4.25e-46	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKNGKOGP_03094	2.21e-67	-	-	GT4	M	ko:K02840	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyl transferases group 1
HKNGKOGP_03097	9.22e-19	cps3F	-	-	-	-	-	-	-
HKNGKOGP_03098	3.55e-84	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HKNGKOGP_03099	3.33e-30	-	-	-	S	-	-	-	Acyltransferase family
HKNGKOGP_03101	7.34e-220	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKNGKOGP_03102	2.68e-99	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKNGKOGP_03103	2.72e-09	-	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HKNGKOGP_03104	1.82e-80	tnp2	-	-	L	ko:K07485	-	ko00000	Transposase
HKNGKOGP_03105	3.78e-200	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKNGKOGP_03106	5.17e-113	-	-	-	L	-	-	-	Integrase
HKNGKOGP_03107	1.15e-41	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKNGKOGP_03108	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HKNGKOGP_03109	1.66e-167	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKNGKOGP_03110	2.49e-95	-	-	-	-	-	-	-	-
HKNGKOGP_03111	3.38e-70	-	-	-	-	-	-	-	-
HKNGKOGP_03112	1.7e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKNGKOGP_03113	7.01e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKNGKOGP_03114	8.04e-190	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKNGKOGP_03115	3.15e-158	-	-	-	T	-	-	-	EAL domain
HKNGKOGP_03116	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKNGKOGP_03117	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKNGKOGP_03118	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HKNGKOGP_03119	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKNGKOGP_03120	2.7e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HKNGKOGP_03121	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKNGKOGP_03122	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKNGKOGP_03123	4.07e-79	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKNGKOGP_03124	1.99e-102	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKNGKOGP_03125	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HKNGKOGP_03126	1.79e-80	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKNGKOGP_03127	3.9e-85	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKNGKOGP_03128	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKNGKOGP_03129	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKNGKOGP_03130	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HKNGKOGP_03131	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKNGKOGP_03132	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKNGKOGP_03133	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKNGKOGP_03134	4.62e-136	-	-	-	-	-	-	-	-
HKNGKOGP_03135	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKNGKOGP_03136	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKNGKOGP_03137	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKNGKOGP_03138	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKNGKOGP_03139	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKNGKOGP_03140	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HKNGKOGP_03141	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKNGKOGP_03142	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKNGKOGP_03143	5.29e-144	-	-	-	-	-	-	-	-
HKNGKOGP_03144	1.5e-32	-	-	-	-	-	-	-	-
HKNGKOGP_03145	1.71e-65	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNGKOGP_03146	2.32e-218	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNGKOGP_03147	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKNGKOGP_03148	1.07e-249	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKNGKOGP_03149	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKNGKOGP_03150	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HKNGKOGP_03151	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HKNGKOGP_03153	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKNGKOGP_03154	8.95e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNGKOGP_03155	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKNGKOGP_03156	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKNGKOGP_03157	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKNGKOGP_03158	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKNGKOGP_03159	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKNGKOGP_03160	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKNGKOGP_03161	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKNGKOGP_03162	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKNGKOGP_03163	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKNGKOGP_03164	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKNGKOGP_03165	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HKNGKOGP_03166	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HKNGKOGP_03167	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HKNGKOGP_03168	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKNGKOGP_03169	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKNGKOGP_03170	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKNGKOGP_03171	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKNGKOGP_03172	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKNGKOGP_03173	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKNGKOGP_03174	7.91e-172	-	-	-	T	-	-	-	diguanylate cyclase activity
HKNGKOGP_03175	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HKNGKOGP_03176	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HKNGKOGP_03177	6.83e-256	-	-	-	S	-	-	-	Protein conserved in bacteria
HKNGKOGP_03178	4.95e-310	-	-	-	-	-	-	-	-
HKNGKOGP_03179	2.6e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKNGKOGP_03180	0.0	nox	-	-	C	-	-	-	NADH oxidase
HKNGKOGP_03181	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKNGKOGP_03182	1.47e-46	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKNGKOGP_03183	6.73e-148	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKNGKOGP_03184	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKNGKOGP_03185	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKNGKOGP_03186	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKNGKOGP_03187	2.16e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HKNGKOGP_03188	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HKNGKOGP_03189	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKNGKOGP_03190	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKNGKOGP_03191	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKNGKOGP_03192	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKNGKOGP_03193	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKNGKOGP_03194	1.19e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKNGKOGP_03195	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKNGKOGP_03196	5.05e-78	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKNGKOGP_03197	3.79e-78	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKNGKOGP_03198	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKNGKOGP_03199	1.78e-52	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKNGKOGP_03200	2.53e-159	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKNGKOGP_03201	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKNGKOGP_03202	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKNGKOGP_03203	3.43e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKNGKOGP_03204	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HKNGKOGP_03205	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKNGKOGP_03206	7.67e-198	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKNGKOGP_03207	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HKNGKOGP_03208	0.0	ydaO	-	-	E	-	-	-	amino acid
HKNGKOGP_03209	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKNGKOGP_03210	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKNGKOGP_03211	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKNGKOGP_03212	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKNGKOGP_03213	7.3e-285	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HKNGKOGP_03214	2.44e-95	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein