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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
GIIPGHNE_00001	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GIIPGHNE_00002	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GIIPGHNE_00003	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
GIIPGHNE_00004	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
GIIPGHNE_00005	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GIIPGHNE_00006	2.21e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
GIIPGHNE_00007	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GIIPGHNE_00008	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
GIIPGHNE_00009	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
GIIPGHNE_00010	4.14e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
GIIPGHNE_00011	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GIIPGHNE_00012	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
GIIPGHNE_00013	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00014	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GIIPGHNE_00015	2.91e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
GIIPGHNE_00016	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GIIPGHNE_00017	1.34e-114	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
GIIPGHNE_00018	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
GIIPGHNE_00019	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
GIIPGHNE_00020	1.35e-149	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
GIIPGHNE_00021	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GIIPGHNE_00022	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GIIPGHNE_00023	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GIIPGHNE_00024	1.35e-300	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
GIIPGHNE_00025	2.1e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GIIPGHNE_00026	3.15e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GIIPGHNE_00028	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GIIPGHNE_00029	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
GIIPGHNE_00030	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GIIPGHNE_00031	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
GIIPGHNE_00032	1.2e-106	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
GIIPGHNE_00033	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
GIIPGHNE_00034	2.63e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GIIPGHNE_00035	8.4e-290	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
GIIPGHNE_00036	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
GIIPGHNE_00037	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
GIIPGHNE_00038	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
GIIPGHNE_00039	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GIIPGHNE_00040	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
GIIPGHNE_00041	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
GIIPGHNE_00042	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
GIIPGHNE_00043	1.34e-52	-	-	-	-	-	-	-	-
GIIPGHNE_00044	1.67e-107	uspA	-	-	T	-	-	-	universal stress protein
GIIPGHNE_00045	9.45e-260	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
GIIPGHNE_00046	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_00047	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
GIIPGHNE_00048	6.54e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
GIIPGHNE_00049	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GIIPGHNE_00050	1.33e-226	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
GIIPGHNE_00051	1.93e-214	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GIIPGHNE_00052	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GIIPGHNE_00053	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_00054	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GIIPGHNE_00055	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
GIIPGHNE_00056	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
GIIPGHNE_00057	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
GIIPGHNE_00058	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
GIIPGHNE_00059	2.91e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
GIIPGHNE_00060	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GIIPGHNE_00061	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GIIPGHNE_00062	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
GIIPGHNE_00063	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GIIPGHNE_00064	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GIIPGHNE_00065	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GIIPGHNE_00066	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GIIPGHNE_00067	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GIIPGHNE_00068	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GIIPGHNE_00069	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
GIIPGHNE_00070	2.49e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
GIIPGHNE_00071	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GIIPGHNE_00072	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GIIPGHNE_00073	5.12e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GIIPGHNE_00074	9.87e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GIIPGHNE_00075	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GIIPGHNE_00076	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
GIIPGHNE_00077	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
GIIPGHNE_00078	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
GIIPGHNE_00079	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GIIPGHNE_00080	6.5e-246	ampC	-	-	V	-	-	-	Beta-lactamase
GIIPGHNE_00081	2.1e-41	-	-	-	-	-	-	-	-
GIIPGHNE_00082	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
GIIPGHNE_00083	1.33e-77	-	-	-	-	-	-	-	-
GIIPGHNE_00084	1.08e-181	-	-	-	-	-	-	-	-
GIIPGHNE_00085	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
GIIPGHNE_00086	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00087	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
GIIPGHNE_00088	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
GIIPGHNE_00089	5.25e-58	-	-	-	K	-	-	-	IrrE N-terminal-like domain
GIIPGHNE_00091	5.08e-57	-	-	-	S	-	-	-	Bacteriophage holin
GIIPGHNE_00092	2.17e-62	-	-	-	-	-	-	-	-
GIIPGHNE_00093	2.87e-251	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
GIIPGHNE_00095	9.16e-26	-	-	-	-	-	-	-	-
GIIPGHNE_00096	3.67e-78	-	-	-	-	-	-	-	-
GIIPGHNE_00099	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GIIPGHNE_00100	9.28e-14	-	-	-	-	-	-	-	-
GIIPGHNE_00102	1.95e-82	-	-	-	S	-	-	-	Prophage endopeptidase tail
GIIPGHNE_00104	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
GIIPGHNE_00105	6.48e-128	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
GIIPGHNE_00107	6.86e-100	-	-	-	-	-	-	-	-
GIIPGHNE_00108	2.97e-86	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
GIIPGHNE_00109	3.53e-62	-	-	-	S	-	-	-	Minor capsid protein
GIIPGHNE_00110	1.51e-71	-	-	-	S	-	-	-	Minor capsid protein
GIIPGHNE_00111	6.28e-11	-	-	-	-	-	-	-	-
GIIPGHNE_00112	1.55e-127	-	-	-	-	-	-	-	-
GIIPGHNE_00113	3.01e-87	-	-	-	S	-	-	-	Phage minor structural protein GP20
GIIPGHNE_00114	3.16e-213	-	-	-	S	-	-	-	Phage minor capsid protein 2
GIIPGHNE_00115	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
GIIPGHNE_00116	0.0	-	-	-	S	-	-	-	Phage terminase large subunit
GIIPGHNE_00117	1.9e-89	-	-	-	S	-	-	-	Terminase small subunit
GIIPGHNE_00122	3.86e-107	arpU	-	-	S	-	-	-	Transcriptional regulator, ArpU family
GIIPGHNE_00123	2.11e-07	-	-	-	-	-	-	-	-
GIIPGHNE_00124	1.91e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
GIIPGHNE_00125	1.19e-108	-	-	-	-	-	-	-	-
GIIPGHNE_00126	1.28e-82	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
GIIPGHNE_00127	2.49e-193	-	-	-	S	-	-	-	IstB-like ATP binding protein
GIIPGHNE_00128	3.06e-38	-	-	-	L	-	-	-	DnaD domain protein
GIIPGHNE_00129	2.52e-56	-	-	-	S	-	-	-	Single-strand binding protein family
GIIPGHNE_00130	1.19e-79	-	-	-	S	-	-	-	ERF superfamily
GIIPGHNE_00131	2.33e-107	-	-	-	-	-	-	-	-
GIIPGHNE_00135	7.62e-120	-	-	-	-	-	-	-	-
GIIPGHNE_00139	9.87e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_00144	1.03e-200	dcm	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
GIIPGHNE_00145	1.83e-104	-	-	-	S	-	-	-	Protein of unknown function DUF262
GIIPGHNE_00146	2.25e-37	-	-	-	-	-	-	-	-
GIIPGHNE_00147	1.56e-277	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GIIPGHNE_00149	2.82e-40	-	-	-	-	-	-	-	-
GIIPGHNE_00151	1.28e-51	-	-	-	-	-	-	-	-
GIIPGHNE_00152	1.87e-57	-	-	-	-	-	-	-	-
GIIPGHNE_00153	3e-108	-	-	-	K	-	-	-	MarR family
GIIPGHNE_00154	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
GIIPGHNE_00155	9.32e-10	-	-	-	D	-	-	-	nuclear chromosome segregation
GIIPGHNE_00156	3.94e-228	inlJ	-	-	M	-	-	-	MucBP domain
GIIPGHNE_00157	9.05e-22	-	-	-	-	-	-	-	-
GIIPGHNE_00158	1.1e-22	-	-	-	-	-	-	-	-
GIIPGHNE_00159	9.85e-22	-	-	-	-	-	-	-	-
GIIPGHNE_00160	6.21e-26	-	-	-	-	-	-	-	-
GIIPGHNE_00161	1.07e-26	-	-	-	-	-	-	-	-
GIIPGHNE_00162	2.16e-26	-	-	-	-	-	-	-	-
GIIPGHNE_00163	4.63e-24	-	-	-	-	-	-	-	-
GIIPGHNE_00164	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
GIIPGHNE_00165	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GIIPGHNE_00166	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00167	2.1e-33	-	-	-	-	-	-	-	-
GIIPGHNE_00168	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
GIIPGHNE_00169	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GIIPGHNE_00170	5.23e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
GIIPGHNE_00171	0.0	yclK	-	-	T	-	-	-	Histidine kinase
GIIPGHNE_00172	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
GIIPGHNE_00173	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
GIIPGHNE_00174	6.12e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
GIIPGHNE_00175	6.53e-138	-	-	-	EG	-	-	-	EamA-like transporter family
GIIPGHNE_00176	3.44e-39	-	-	-	EG	-	-	-	EamA-like transporter family
GIIPGHNE_00178	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
GIIPGHNE_00179	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
GIIPGHNE_00180	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
GIIPGHNE_00181	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
GIIPGHNE_00182	1.09e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GIIPGHNE_00183	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GIIPGHNE_00184	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
GIIPGHNE_00185	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
GIIPGHNE_00186	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
GIIPGHNE_00187	1.3e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
GIIPGHNE_00188	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GIIPGHNE_00189	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GIIPGHNE_00190	1.14e-177	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
GIIPGHNE_00191	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
GIIPGHNE_00211	6.29e-99	-	-	-	M	-	-	-	PFAM NLP P60 protein
GIIPGHNE_00212	6.18e-71	-	-	-	-	-	-	-	-
GIIPGHNE_00213	1.12e-78	-	-	-	-	-	-	-	-
GIIPGHNE_00215	7.28e-138	-	-	-	-	-	-	-	-
GIIPGHNE_00216	2.89e-67	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
GIIPGHNE_00217	9.31e-204	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
GIIPGHNE_00218	4.22e-130	-	-	-	K	-	-	-	transcriptional regulator
GIIPGHNE_00219	1.24e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
GIIPGHNE_00220	6.91e-174	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GIIPGHNE_00221	5.88e-163	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
GIIPGHNE_00222	4.86e-233	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GIIPGHNE_00223	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
GIIPGHNE_00224	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GIIPGHNE_00225	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
GIIPGHNE_00226	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
GIIPGHNE_00227	1.01e-26	-	-	-	-	-	-	-	-
GIIPGHNE_00228	4.27e-126	dpsB	-	-	P	-	-	-	Belongs to the Dps family
GIIPGHNE_00229	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
GIIPGHNE_00230	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
GIIPGHNE_00231	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GIIPGHNE_00232	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GIIPGHNE_00233	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
GIIPGHNE_00234	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
GIIPGHNE_00235	7.47e-235	-	-	-	S	-	-	-	Cell surface protein
GIIPGHNE_00236	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_00237	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_00238	7.83e-60	-	-	-	-	-	-	-	-
GIIPGHNE_00239	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
GIIPGHNE_00240	1.03e-65	-	-	-	-	-	-	-	-
GIIPGHNE_00241	9.34e-317	-	-	-	S	-	-	-	Putative metallopeptidase domain
GIIPGHNE_00242	3.31e-282	-	-	-	S	-	-	-	associated with various cellular activities
GIIPGHNE_00243	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GIIPGHNE_00244	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
GIIPGHNE_00245	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GIIPGHNE_00246	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
GIIPGHNE_00247	4.12e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
GIIPGHNE_00248	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
GIIPGHNE_00249	4.16e-297	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
GIIPGHNE_00250	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GIIPGHNE_00251	3.38e-50	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GIIPGHNE_00252	1.11e-33	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GIIPGHNE_00253	6.61e-29	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GIIPGHNE_00254	5.55e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
GIIPGHNE_00255	1.55e-230	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GIIPGHNE_00256	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
GIIPGHNE_00257	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GIIPGHNE_00258	1.92e-285	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GIIPGHNE_00259	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
GIIPGHNE_00260	1.84e-235	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
GIIPGHNE_00261	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
GIIPGHNE_00262	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GIIPGHNE_00263	5.81e-251	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
GIIPGHNE_00264	6.11e-231	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GIIPGHNE_00265	5.16e-248	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
GIIPGHNE_00266	1.77e-19	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
GIIPGHNE_00267	3.47e-52	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
GIIPGHNE_00268	6.54e-196	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GIIPGHNE_00269	2.2e-103	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
GIIPGHNE_00270	4.06e-165	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_00271	2.02e-158	-	-	-	G	ko:K02025,ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_00272	2.29e-198	-	-	-	G	ko:K02027,ko:K10120	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
GIIPGHNE_00273	3.2e-292	-	2.4.1.332	GH65	G	ko:K04844,ko:K21355	-	ko00000,ko01000	Glycosyl hydrolase family 65, C-terminal domain
GIIPGHNE_00277	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GIIPGHNE_00278	1.38e-225	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GIIPGHNE_00279	1.36e-167	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GIIPGHNE_00280	4.63e-275	-	-	-	G	-	-	-	Transporter
GIIPGHNE_00281	1.66e-215	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GIIPGHNE_00282	5.79e-209	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
GIIPGHNE_00283	4.74e-268	-	-	-	G	-	-	-	Major Facilitator Superfamily
GIIPGHNE_00284	2.09e-83	-	-	-	-	-	-	-	-
GIIPGHNE_00285	1.78e-198	estA	-	-	S	-	-	-	Putative esterase
GIIPGHNE_00286	1.82e-172	-	-	-	K	-	-	-	UTRA domain
GIIPGHNE_00287	1.87e-316	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_00288	1.25e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GIIPGHNE_00289	3.97e-201	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
GIIPGHNE_00290	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
GIIPGHNE_00291	8.74e-151	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GIIPGHNE_00292	4.69e-316	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GIIPGHNE_00293	0.0	-	-	-	C	-	-	-	FAD binding domain
GIIPGHNE_00294	5.75e-111	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GIIPGHNE_00295	1.25e-311	-	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Alpha mannosidase, middle domain
GIIPGHNE_00296	3.93e-57	-	-	-	GT	-	-	-	Phosphotransferase System
GIIPGHNE_00297	1.81e-190	-	-	-	GT	-	-	-	Phosphotransferase System
GIIPGHNE_00298	1.55e-65	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GIIPGHNE_00299	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_00300	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GIIPGHNE_00301	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GIIPGHNE_00302	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_00303	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_00304	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GIIPGHNE_00305	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GIIPGHNE_00306	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
GIIPGHNE_00307	8.88e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
GIIPGHNE_00308	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GIIPGHNE_00309	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
GIIPGHNE_00311	2.83e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GIIPGHNE_00312	4.28e-185	yxeH	-	-	S	-	-	-	hydrolase
GIIPGHNE_00313	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GIIPGHNE_00314	1.02e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GIIPGHNE_00315	3.15e-162	alsE	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
GIIPGHNE_00316	3.64e-224	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
GIIPGHNE_00317	2.55e-62	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GIIPGHNE_00318	2.71e-98	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GIIPGHNE_00320	3.46e-307	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
GIIPGHNE_00321	1.32e-240	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
GIIPGHNE_00322	1.69e-295	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
GIIPGHNE_00323	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GIIPGHNE_00324	3.53e-100	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GIIPGHNE_00325	6.69e-149	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
GIIPGHNE_00326	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
GIIPGHNE_00327	6.55e-62	icaB	-	-	G	ko:K21478	-	ko00000,ko01000	Polysaccharide deacetylase
GIIPGHNE_00329	1.35e-114	icaA	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyltransferases, probably involved in cell wall biogenesis
GIIPGHNE_00330	1.22e-20	icaA	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyltransferases, probably involved in cell wall biogenesis
GIIPGHNE_00331	3.64e-151	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GIIPGHNE_00332	7.62e-290	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
GIIPGHNE_00333	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
GIIPGHNE_00334	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
GIIPGHNE_00335	1.06e-16	-	-	-	-	-	-	-	-
GIIPGHNE_00336	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
GIIPGHNE_00337	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
GIIPGHNE_00338	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
GIIPGHNE_00339	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
GIIPGHNE_00340	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GIIPGHNE_00341	9.62e-19	-	-	-	-	-	-	-	-
GIIPGHNE_00342	6.12e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
GIIPGHNE_00343	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
GIIPGHNE_00345	1.14e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
GIIPGHNE_00346	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GIIPGHNE_00347	2.91e-94	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_00348	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GIIPGHNE_00349	2.33e-81	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
GIIPGHNE_00350	5.04e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
GIIPGHNE_00351	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
GIIPGHNE_00352	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
GIIPGHNE_00353	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
GIIPGHNE_00354	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
GIIPGHNE_00355	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
GIIPGHNE_00356	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GIIPGHNE_00357	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIIPGHNE_00358	1.88e-240	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
GIIPGHNE_00359	3.36e-06	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
GIIPGHNE_00360	2.84e-09	-	-	-	-	-	-	-	-
GIIPGHNE_00361	6.69e-39	-	-	-	-	-	-	-	-
GIIPGHNE_00362	2.37e-65	-	-	-	-	-	-	-	-
GIIPGHNE_00363	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
GIIPGHNE_00364	5.5e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
GIIPGHNE_00366	3.29e-53	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
GIIPGHNE_00367	2.98e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
GIIPGHNE_00368	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
GIIPGHNE_00369	1.23e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GIIPGHNE_00370	3.56e-172	-	-	-	-	-	-	-	-
GIIPGHNE_00371	3.06e-75	-	-	-	-	-	-	-	-
GIIPGHNE_00372	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
GIIPGHNE_00373	1.12e-288	-	-	-	-	-	-	-	-
GIIPGHNE_00374	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
GIIPGHNE_00375	8.51e-243	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
GIIPGHNE_00376	1.66e-249	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GIIPGHNE_00377	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GIIPGHNE_00378	3.31e-98	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
GIIPGHNE_00379	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GIIPGHNE_00380	5.9e-289	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
GIIPGHNE_00381	1.98e-66	-	-	-	-	-	-	-	-
GIIPGHNE_00382	9.28e-308	-	-	-	M	-	-	-	Glycosyl transferase family group 2
GIIPGHNE_00383	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GIIPGHNE_00384	5.1e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
GIIPGHNE_00385	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
GIIPGHNE_00386	2.16e-124	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GIIPGHNE_00387	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
GIIPGHNE_00388	3.91e-216	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
GIIPGHNE_00389	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_00390	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GIIPGHNE_00391	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GIIPGHNE_00392	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GIIPGHNE_00393	1.48e-216	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
GIIPGHNE_00394	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GIIPGHNE_00395	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GIIPGHNE_00396	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
GIIPGHNE_00397	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GIIPGHNE_00398	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GIIPGHNE_00399	3.85e-201	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
GIIPGHNE_00400	1.37e-173	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GIIPGHNE_00401	6.46e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GIIPGHNE_00403	8.51e-291	XK27_05470	-	-	E	-	-	-	Methionine synthase
GIIPGHNE_00404	2.11e-220	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
GIIPGHNE_00405	1.55e-223	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
GIIPGHNE_00406	1.01e-159	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
GIIPGHNE_00407	1.49e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
GIIPGHNE_00408	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_00409	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
GIIPGHNE_00410	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
GIIPGHNE_00411	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
GIIPGHNE_00412	5.91e-209	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
GIIPGHNE_00413	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
GIIPGHNE_00414	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GIIPGHNE_00415	5.51e-240	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GIIPGHNE_00416	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00417	6.46e-109	-	-	-	-	-	-	-	-
GIIPGHNE_00418	5.18e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GIIPGHNE_00419	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GIIPGHNE_00420	1.84e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GIIPGHNE_00421	2.08e-284	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
GIIPGHNE_00422	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GIIPGHNE_00423	4.84e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
GIIPGHNE_00424	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
GIIPGHNE_00425	7.34e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
GIIPGHNE_00426	1.25e-39	-	-	-	M	-	-	-	Lysin motif
GIIPGHNE_00427	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
GIIPGHNE_00428	8.91e-248	-	-	-	S	-	-	-	Helix-turn-helix domain
GIIPGHNE_00429	1.84e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GIIPGHNE_00430	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GIIPGHNE_00431	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GIIPGHNE_00432	2.38e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GIIPGHNE_00433	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GIIPGHNE_00434	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
GIIPGHNE_00435	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
GIIPGHNE_00436	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
GIIPGHNE_00437	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
GIIPGHNE_00438	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GIIPGHNE_00439	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
GIIPGHNE_00440	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
GIIPGHNE_00442	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GIIPGHNE_00443	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GIIPGHNE_00444	1.61e-251	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GIIPGHNE_00445	8.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
GIIPGHNE_00446	2.38e-293	-	-	-	M	-	-	-	O-Antigen ligase
GIIPGHNE_00447	1.46e-164	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
GIIPGHNE_00448	4.49e-208	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_00449	6.45e-111	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GIIPGHNE_00450	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
GIIPGHNE_00451	4.58e-82	-	-	-	P	-	-	-	Rhodanese Homology Domain
GIIPGHNE_00452	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GIIPGHNE_00453	7.53e-264	-	-	-	-	-	-	-	-
GIIPGHNE_00454	1.49e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
GIIPGHNE_00455	4.32e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
GIIPGHNE_00456	1.24e-191	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
GIIPGHNE_00457	2.14e-307	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
GIIPGHNE_00458	1.09e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GIIPGHNE_00459	1.54e-305	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
GIIPGHNE_00460	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_00461	1.12e-265	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
GIIPGHNE_00462	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GIIPGHNE_00463	8.01e-175	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
GIIPGHNE_00464	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
GIIPGHNE_00465	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
GIIPGHNE_00466	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
GIIPGHNE_00467	1.99e-146	-	-	-	GM	-	-	-	epimerase
GIIPGHNE_00468	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
GIIPGHNE_00469	1.69e-153	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
GIIPGHNE_00470	2.72e-115	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
GIIPGHNE_00471	6.58e-165	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GIIPGHNE_00472	4.37e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
GIIPGHNE_00473	5.05e-146	-	-	-	GM	-	-	-	NmrA-like family
GIIPGHNE_00474	2.12e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
GIIPGHNE_00475	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_00476	3.11e-220	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
GIIPGHNE_00478	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GIIPGHNE_00479	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
GIIPGHNE_00480	2.49e-257	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GIIPGHNE_00481	5.79e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
GIIPGHNE_00482	4.66e-201	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_00483	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
GIIPGHNE_00484	9.55e-95	-	-	-	K	-	-	-	MarR family
GIIPGHNE_00485	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
GIIPGHNE_00486	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
GIIPGHNE_00487	1.25e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00488	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GIIPGHNE_00489	3.67e-254	-	-	-	-	-	-	-	-
GIIPGHNE_00490	7.12e-254	-	-	-	-	-	-	-	-
GIIPGHNE_00491	7.01e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00492	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
GIIPGHNE_00493	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GIIPGHNE_00494	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GIIPGHNE_00495	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
GIIPGHNE_00496	2.48e-223	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
GIIPGHNE_00497	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
GIIPGHNE_00498	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GIIPGHNE_00499	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
GIIPGHNE_00500	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GIIPGHNE_00501	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
GIIPGHNE_00502	1.22e-83	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
GIIPGHNE_00503	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
GIIPGHNE_00504	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GIIPGHNE_00505	7.06e-164	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
GIIPGHNE_00506	2.87e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GIIPGHNE_00507	2.29e-279	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GIIPGHNE_00508	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GIIPGHNE_00509	3.71e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GIIPGHNE_00510	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GIIPGHNE_00511	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
GIIPGHNE_00512	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
GIIPGHNE_00513	4.4e-212	-	-	-	G	-	-	-	Fructosamine kinase
GIIPGHNE_00514	5.97e-151	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
GIIPGHNE_00515	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GIIPGHNE_00516	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GIIPGHNE_00517	2.56e-76	-	-	-	-	-	-	-	-
GIIPGHNE_00518	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GIIPGHNE_00519	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
GIIPGHNE_00520	3.87e-148	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
GIIPGHNE_00521	4.78e-65	-	-	-	-	-	-	-	-
GIIPGHNE_00522	1.73e-67	-	-	-	-	-	-	-	-
GIIPGHNE_00525	1.43e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GIIPGHNE_00526	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GIIPGHNE_00527	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GIIPGHNE_00528	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GIIPGHNE_00529	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
GIIPGHNE_00530	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GIIPGHNE_00531	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
GIIPGHNE_00532	1.26e-267	pbpX2	-	-	V	-	-	-	Beta-lactamase
GIIPGHNE_00533	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GIIPGHNE_00534	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
GIIPGHNE_00535	4.72e-113	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GIIPGHNE_00536	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GIIPGHNE_00537	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
GIIPGHNE_00538	2.17e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
GIIPGHNE_00539	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GIIPGHNE_00540	3.99e-112	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GIIPGHNE_00541	3.62e-247	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
GIIPGHNE_00542	9.14e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GIIPGHNE_00543	9.84e-123	-	-	-	-	-	-	-	-
GIIPGHNE_00544	1.05e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GIIPGHNE_00545	0.0	-	-	-	G	-	-	-	Major Facilitator
GIIPGHNE_00546	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GIIPGHNE_00547	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GIIPGHNE_00548	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
GIIPGHNE_00549	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
GIIPGHNE_00550	3.14e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
GIIPGHNE_00551	3.97e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
GIIPGHNE_00552	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GIIPGHNE_00553	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GIIPGHNE_00554	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
GIIPGHNE_00555	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
GIIPGHNE_00556	9.1e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GIIPGHNE_00557	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GIIPGHNE_00558	2.47e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
GIIPGHNE_00559	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GIIPGHNE_00560	3.66e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
GIIPGHNE_00561	1.19e-171	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
GIIPGHNE_00562	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GIIPGHNE_00563	9.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
GIIPGHNE_00564	3.65e-172	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
GIIPGHNE_00565	1.71e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
GIIPGHNE_00566	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
GIIPGHNE_00567	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
GIIPGHNE_00568	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GIIPGHNE_00569	6.4e-122	-	-	-	-	-	-	-	-
GIIPGHNE_00570	6.62e-278	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
GIIPGHNE_00571	1.01e-100	-	-	-	-	-	-	-	-
GIIPGHNE_00572	3.81e-87	-	-	-	-	-	-	-	-
GIIPGHNE_00573	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
GIIPGHNE_00574	6.27e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
GIIPGHNE_00575	5.21e-280	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
GIIPGHNE_00576	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GIIPGHNE_00577	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_00578	1.88e-291	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
GIIPGHNE_00580	1.96e-53	-	-	-	S	-	-	-	Bacteriophage holin
GIIPGHNE_00581	7.25e-47	-	-	-	S	-	-	-	Haemolysin XhlA
GIIPGHNE_00582	6.4e-258	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
GIIPGHNE_00583	7.94e-67	-	-	-	-	-	-	-	-
GIIPGHNE_00587	0.0	-	-	-	S	-	-	-	Phage minor structural protein
GIIPGHNE_00588	7.83e-284	-	-	-	S	-	-	-	Phage tail protein
GIIPGHNE_00589	0.0	-	-	-	D	-	-	-	domain protein
GIIPGHNE_00590	2.09e-26	-	-	-	-	-	-	-	-
GIIPGHNE_00591	2.25e-74	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
GIIPGHNE_00592	1.42e-138	-	-	-	S	-	-	-	Phage tail tube protein
GIIPGHNE_00593	7.78e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
GIIPGHNE_00594	6.72e-88	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
GIIPGHNE_00595	2.73e-73	-	-	-	S	-	-	-	Phage head-tail joining protein
GIIPGHNE_00596	5.64e-66	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
GIIPGHNE_00597	8.18e-269	-	-	-	S	-	-	-	Phage capsid family
GIIPGHNE_00598	1.53e-159	-	-	-	S	-	-	-	Clp protease
GIIPGHNE_00599	4.21e-285	-	-	-	S	-	-	-	Phage portal protein
GIIPGHNE_00600	1.64e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
GIIPGHNE_00601	0.0	-	-	-	S	-	-	-	Phage Terminase
GIIPGHNE_00602	7.49e-102	-	-	-	S	-	-	-	Phage terminase, small subunit
GIIPGHNE_00603	4.2e-117	-	-	-	L	-	-	-	HNH nucleases
GIIPGHNE_00604	2.14e-20	-	-	-	-	-	-	-	-
GIIPGHNE_00605	1.33e-100	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
GIIPGHNE_00606	1.32e-24	-	-	-	-	-	-	-	-
GIIPGHNE_00607	9.84e-17	-	-	-	-	-	-	-	-
GIIPGHNE_00609	2e-33	-	-	-	S	-	-	-	YopX protein
GIIPGHNE_00611	1.69e-19	-	-	-	-	-	-	-	-
GIIPGHNE_00613	5.4e-62	-	-	-	-	-	-	-	-
GIIPGHNE_00615	3.27e-184	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
GIIPGHNE_00616	3.09e-93	-	-	-	L	-	-	-	DnaD domain protein
GIIPGHNE_00617	5.27e-170	-	-	-	S	-	-	-	Putative HNHc nuclease
GIIPGHNE_00619	1.7e-120	-	-	-	S	-	-	-	AAA domain
GIIPGHNE_00620	1.42e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
GIIPGHNE_00622	2.34e-24	-	-	-	-	-	-	-	-
GIIPGHNE_00631	4.55e-77	-	-	-	S	-	-	-	ORF6C domain
GIIPGHNE_00633	3.49e-30	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_00634	6.22e-48	-	-	-	S	-	-	-	Pfam:Peptidase_M78
GIIPGHNE_00640	1.55e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GIIPGHNE_00641	5.03e-43	-	-	-	-	-	-	-	-
GIIPGHNE_00642	4.65e-155	-	-	-	Q	-	-	-	Methyltransferase
GIIPGHNE_00643	4.71e-74	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
GIIPGHNE_00644	1.66e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
GIIPGHNE_00645	7.9e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
GIIPGHNE_00646	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GIIPGHNE_00647	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
GIIPGHNE_00648	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
GIIPGHNE_00649	1.67e-178	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
GIIPGHNE_00650	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GIIPGHNE_00651	6.62e-62	-	-	-	-	-	-	-	-
GIIPGHNE_00652	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GIIPGHNE_00653	8.65e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
GIIPGHNE_00654	7.34e-219	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GIIPGHNE_00655	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
GIIPGHNE_00656	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
GIIPGHNE_00657	0.0	cps4J	-	-	S	-	-	-	MatE
GIIPGHNE_00658	2.2e-224	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
GIIPGHNE_00659	1.44e-292	-	-	-	-	-	-	-	-
GIIPGHNE_00660	3.29e-236	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
GIIPGHNE_00661	2.22e-256	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
GIIPGHNE_00662	3.18e-162	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
GIIPGHNE_00663	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
GIIPGHNE_00664	9.18e-188	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
GIIPGHNE_00665	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
GIIPGHNE_00666	8.45e-162	epsB	-	-	M	-	-	-	biosynthesis protein
GIIPGHNE_00667	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GIIPGHNE_00668	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00669	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GIIPGHNE_00670	5.12e-31	-	-	-	-	-	-	-	-
GIIPGHNE_00671	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
GIIPGHNE_00672	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
GIIPGHNE_00673	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
GIIPGHNE_00674	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GIIPGHNE_00675	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GIIPGHNE_00676	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GIIPGHNE_00677	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
GIIPGHNE_00678	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GIIPGHNE_00679	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIIPGHNE_00680	2.22e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GIIPGHNE_00681	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GIIPGHNE_00682	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
GIIPGHNE_00683	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
GIIPGHNE_00684	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
GIIPGHNE_00685	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
GIIPGHNE_00686	7.77e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
GIIPGHNE_00687	3.01e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
GIIPGHNE_00688	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GIIPGHNE_00689	3.51e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
GIIPGHNE_00690	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
GIIPGHNE_00691	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GIIPGHNE_00692	7.19e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GIIPGHNE_00694	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_00695	2.67e-297	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
GIIPGHNE_00696	8.39e-38	-	-	-	-	-	-	-	-
GIIPGHNE_00698	6.31e-20	-	-	-	-	-	-	-	-
GIIPGHNE_00699	1.37e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
GIIPGHNE_00700	1.37e-67	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_00701	3.28e-33	-	-	-	-	-	-	-	-
GIIPGHNE_00702	2.06e-56	-	-	-	K	-	-	-	Helix-turn-helix domain
GIIPGHNE_00703	6.7e-74	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
GIIPGHNE_00704	1.41e-134	-	-	-	L	-	-	-	Phage integrase family
GIIPGHNE_00715	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
GIIPGHNE_00716	5.46e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
GIIPGHNE_00717	9.4e-32	-	-	-	-	-	-	-	-
GIIPGHNE_00718	2.95e-75	-	-	-	-	-	-	-	-
GIIPGHNE_00719	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_00720	2.94e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
GIIPGHNE_00722	3.8e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GIIPGHNE_00723	6.95e-238	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
GIIPGHNE_00724	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GIIPGHNE_00725	1.31e-214	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
GIIPGHNE_00726	1.59e-285	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GIIPGHNE_00727	2.41e-58	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GIIPGHNE_00728	3.35e-157	-	-	-	-	-	-	-	-
GIIPGHNE_00729	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GIIPGHNE_00730	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_00731	3.2e-141	-	-	-	N	-	-	-	Cell shape-determining protein MreB
GIIPGHNE_00732	6.16e-180	-	-	-	N	-	-	-	Cell shape-determining protein MreB
GIIPGHNE_00733	5.42e-193	-	-	-	S	-	-	-	Pfam Methyltransferase
GIIPGHNE_00734	1.09e-161	-	-	-	S	-	-	-	Pfam Methyltransferase
GIIPGHNE_00735	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GIIPGHNE_00736	1.64e-315	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GIIPGHNE_00737	2.45e-43	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GIIPGHNE_00738	9.32e-40	-	-	-	-	-	-	-	-
GIIPGHNE_00739	7.15e-121	mraW1	-	-	J	-	-	-	Putative rRNA methylase
GIIPGHNE_00740	3.58e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
GIIPGHNE_00741	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
GIIPGHNE_00742	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GIIPGHNE_00743	8.35e-175	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GIIPGHNE_00744	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GIIPGHNE_00745	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
GIIPGHNE_00746	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GIIPGHNE_00747	1.02e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
GIIPGHNE_00748	1.87e-220	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_00749	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_00750	3.13e-136	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GIIPGHNE_00751	9.28e-175	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GIIPGHNE_00752	2.13e-146	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
GIIPGHNE_00753	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
GIIPGHNE_00754	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GIIPGHNE_00755	1.07e-162	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
GIIPGHNE_00756	7.74e-161	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
GIIPGHNE_00758	7.33e-164	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
GIIPGHNE_00759	2.06e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_00760	1.42e-223	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
GIIPGHNE_00762	1.11e-113	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GIIPGHNE_00763	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_00764	1.64e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
GIIPGHNE_00765	4.44e-203	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GIIPGHNE_00766	1.33e-189	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GIIPGHNE_00767	7.83e-140	-	-	-	-	-	-	-	-
GIIPGHNE_00768	1.46e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GIIPGHNE_00769	3.14e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
GIIPGHNE_00770	8.92e-73	-	-	-	-	-	-	-	-
GIIPGHNE_00771	4.56e-78	-	-	-	-	-	-	-	-
GIIPGHNE_00772	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_00773	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
GIIPGHNE_00774	8.82e-119	-	-	-	-	-	-	-	-
GIIPGHNE_00775	7.12e-62	-	-	-	-	-	-	-	-
GIIPGHNE_00776	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
GIIPGHNE_00779	4.29e-87	-	-	-	-	-	-	-	-
GIIPGHNE_00780	9.03e-16	-	-	-	-	-	-	-	-
GIIPGHNE_00781	5.3e-235	-	-	-	-	-	-	-	-
GIIPGHNE_00782	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
GIIPGHNE_00783	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
GIIPGHNE_00784	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GIIPGHNE_00785	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GIIPGHNE_00786	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
GIIPGHNE_00787	1.8e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
GIIPGHNE_00788	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
GIIPGHNE_00789	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
GIIPGHNE_00790	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
GIIPGHNE_00791	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
GIIPGHNE_00792	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
GIIPGHNE_00793	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
GIIPGHNE_00794	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
GIIPGHNE_00795	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GIIPGHNE_00796	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
GIIPGHNE_00797	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
GIIPGHNE_00798	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GIIPGHNE_00799	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GIIPGHNE_00800	1.18e-66	-	-	-	-	-	-	-	-
GIIPGHNE_00801	3e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GIIPGHNE_00802	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
GIIPGHNE_00803	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GIIPGHNE_00804	4.49e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GIIPGHNE_00805	7.7e-255	-	-	-	K	-	-	-	Helix-turn-helix domain
GIIPGHNE_00806	4.28e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
GIIPGHNE_00807	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
GIIPGHNE_00808	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GIIPGHNE_00809	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GIIPGHNE_00810	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GIIPGHNE_00811	4.68e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
GIIPGHNE_00812	1.93e-210	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GIIPGHNE_00813	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GIIPGHNE_00814	4.51e-260	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
GIIPGHNE_00815	3.43e-232	-	-	-	S	-	-	-	Membrane
GIIPGHNE_00816	1.65e-207	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
GIIPGHNE_00817	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
GIIPGHNE_00818	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GIIPGHNE_00819	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GIIPGHNE_00820	2.39e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GIIPGHNE_00821	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GIIPGHNE_00822	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GIIPGHNE_00823	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GIIPGHNE_00824	3.19e-194	-	-	-	S	-	-	-	FMN_bind
GIIPGHNE_00825	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
GIIPGHNE_00826	5.37e-112	-	-	-	S	-	-	-	NusG domain II
GIIPGHNE_00827	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
GIIPGHNE_00828	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GIIPGHNE_00829	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
GIIPGHNE_00830	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GIIPGHNE_00831	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GIIPGHNE_00832	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GIIPGHNE_00833	1.19e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GIIPGHNE_00834	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GIIPGHNE_00835	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GIIPGHNE_00836	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GIIPGHNE_00837	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
GIIPGHNE_00838	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GIIPGHNE_00839	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GIIPGHNE_00840	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GIIPGHNE_00841	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GIIPGHNE_00842	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GIIPGHNE_00843	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GIIPGHNE_00844	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GIIPGHNE_00845	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GIIPGHNE_00846	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
GIIPGHNE_00847	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GIIPGHNE_00848	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GIIPGHNE_00849	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GIIPGHNE_00850	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GIIPGHNE_00851	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GIIPGHNE_00852	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GIIPGHNE_00853	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
GIIPGHNE_00854	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GIIPGHNE_00855	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
GIIPGHNE_00856	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GIIPGHNE_00857	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GIIPGHNE_00858	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GIIPGHNE_00859	4.25e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
GIIPGHNE_00860	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GIIPGHNE_00861	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GIIPGHNE_00862	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_00863	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GIIPGHNE_00864	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
GIIPGHNE_00872	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GIIPGHNE_00873	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
GIIPGHNE_00874	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
GIIPGHNE_00875	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
GIIPGHNE_00876	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GIIPGHNE_00877	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_00878	1.23e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GIIPGHNE_00879	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GIIPGHNE_00880	2.05e-153	-	-	-	I	-	-	-	phosphatase
GIIPGHNE_00881	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GIIPGHNE_00882	1.83e-98	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
GIIPGHNE_00883	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
GIIPGHNE_00884	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
GIIPGHNE_00885	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
GIIPGHNE_00886	1.36e-77	-	-	-	-	-	-	-	-
GIIPGHNE_00887	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
GIIPGHNE_00888	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
GIIPGHNE_00889	1.11e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
GIIPGHNE_00890	1.61e-235	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
GIIPGHNE_00891	8.52e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
GIIPGHNE_00892	4.06e-20	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
GIIPGHNE_00893	9.13e-155	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
GIIPGHNE_00894	1.17e-250	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GIIPGHNE_00895	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
GIIPGHNE_00896	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
GIIPGHNE_00897	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GIIPGHNE_00898	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GIIPGHNE_00899	4.87e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GIIPGHNE_00900	2.5e-188	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GIIPGHNE_00901	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GIIPGHNE_00903	7.97e-108	-	-	-	-	-	-	-	-
GIIPGHNE_00904	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
GIIPGHNE_00906	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
GIIPGHNE_00907	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GIIPGHNE_00908	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
GIIPGHNE_00909	6.83e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
GIIPGHNE_00910	2.71e-76	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
GIIPGHNE_00911	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
GIIPGHNE_00912	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
GIIPGHNE_00913	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
GIIPGHNE_00914	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
GIIPGHNE_00915	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_00917	1.61e-29	-	-	-	-	-	-	-	-
GIIPGHNE_00918	2.26e-123	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
GIIPGHNE_00919	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
GIIPGHNE_00920	1.59e-131	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
GIIPGHNE_00921	9.16e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GIIPGHNE_00922	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
GIIPGHNE_00923	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
GIIPGHNE_00924	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GIIPGHNE_00925	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
GIIPGHNE_00926	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GIIPGHNE_00927	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_00929	1.07e-52	-	-	-	-	-	-	-	-
GIIPGHNE_00930	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GIIPGHNE_00931	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
GIIPGHNE_00932	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GIIPGHNE_00933	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
GIIPGHNE_00934	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
GIIPGHNE_00935	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GIIPGHNE_00936	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GIIPGHNE_00937	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GIIPGHNE_00938	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
GIIPGHNE_00939	2.6e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GIIPGHNE_00940	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GIIPGHNE_00941	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GIIPGHNE_00942	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GIIPGHNE_00943	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
GIIPGHNE_00944	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GIIPGHNE_00945	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
GIIPGHNE_00946	2.61e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
GIIPGHNE_00947	1.29e-150	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
GIIPGHNE_00948	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GIIPGHNE_00949	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
GIIPGHNE_00950	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
GIIPGHNE_00951	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GIIPGHNE_00952	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GIIPGHNE_00953	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GIIPGHNE_00954	4.14e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GIIPGHNE_00955	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GIIPGHNE_00956	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
GIIPGHNE_00957	8.28e-73	-	-	-	-	-	-	-	-
GIIPGHNE_00958	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_00959	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GIIPGHNE_00960	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_00961	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_00962	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
GIIPGHNE_00963	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
GIIPGHNE_00964	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
GIIPGHNE_00965	5.49e-205	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GIIPGHNE_00966	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GIIPGHNE_00967	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GIIPGHNE_00968	1.96e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GIIPGHNE_00969	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GIIPGHNE_00970	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
GIIPGHNE_00971	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GIIPGHNE_00972	6.04e-249	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GIIPGHNE_00973	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
GIIPGHNE_00974	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
GIIPGHNE_00975	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
GIIPGHNE_00976	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_00977	9.81e-27	-	-	-	-	-	-	-	-
GIIPGHNE_00980	2.97e-41	-	-	-	-	-	-	-	-
GIIPGHNE_00981	3.11e-73	-	-	-	-	-	-	-	-
GIIPGHNE_00982	2.92e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
GIIPGHNE_00983	1.34e-232	-	-	-	-	-	-	-	-
GIIPGHNE_00984	7.21e-205	-	-	-	-	-	-	-	-
GIIPGHNE_00985	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
GIIPGHNE_00986	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
GIIPGHNE_00987	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GIIPGHNE_00988	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
GIIPGHNE_00989	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
GIIPGHNE_00990	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
GIIPGHNE_00991	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
GIIPGHNE_00992	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
GIIPGHNE_00993	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
GIIPGHNE_00994	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
GIIPGHNE_00995	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GIIPGHNE_00996	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GIIPGHNE_00997	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GIIPGHNE_00998	0.0	-	-	-	S	-	-	-	membrane
GIIPGHNE_00999	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
GIIPGHNE_01000	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
GIIPGHNE_01001	9.72e-146	-	-	-	S	-	-	-	membrane
GIIPGHNE_01002	8.95e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GIIPGHNE_01003	4.34e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
GIIPGHNE_01004	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GIIPGHNE_01005	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GIIPGHNE_01006	2.3e-255	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GIIPGHNE_01007	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GIIPGHNE_01008	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GIIPGHNE_01009	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIIPGHNE_01010	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
GIIPGHNE_01011	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GIIPGHNE_01012	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
GIIPGHNE_01013	9.59e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GIIPGHNE_01014	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
GIIPGHNE_01015	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
GIIPGHNE_01016	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GIIPGHNE_01017	3.96e-155	csrR	-	-	K	-	-	-	response regulator
GIIPGHNE_01018	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
GIIPGHNE_01019	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GIIPGHNE_01020	6.74e-218	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GIIPGHNE_01021	6.91e-59	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
GIIPGHNE_01022	6.06e-55	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
GIIPGHNE_01023	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
GIIPGHNE_01024	1.76e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
GIIPGHNE_01025	2.71e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
GIIPGHNE_01026	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GIIPGHNE_01027	4.92e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
GIIPGHNE_01028	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GIIPGHNE_01029	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
GIIPGHNE_01030	8.98e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
GIIPGHNE_01031	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
GIIPGHNE_01032	6.32e-114	-	-	-	-	-	-	-	-
GIIPGHNE_01033	1.9e-316	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
GIIPGHNE_01034	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GIIPGHNE_01035	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GIIPGHNE_01036	6.08e-253	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
GIIPGHNE_01037	1.16e-305	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
GIIPGHNE_01038	2.76e-74	-	-	-	-	-	-	-	-
GIIPGHNE_01039	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GIIPGHNE_01040	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
GIIPGHNE_01041	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GIIPGHNE_01042	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GIIPGHNE_01043	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
GIIPGHNE_01044	4.46e-316	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
GIIPGHNE_01045	3.19e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GIIPGHNE_01046	9.54e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GIIPGHNE_01047	2.16e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GIIPGHNE_01048	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GIIPGHNE_01049	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GIIPGHNE_01050	5.18e-142	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
GIIPGHNE_01051	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GIIPGHNE_01052	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
GIIPGHNE_01053	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
GIIPGHNE_01054	6.13e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GIIPGHNE_01055	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
GIIPGHNE_01056	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
GIIPGHNE_01057	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
GIIPGHNE_01058	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
GIIPGHNE_01059	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
GIIPGHNE_01060	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
GIIPGHNE_01061	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GIIPGHNE_01062	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GIIPGHNE_01063	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
GIIPGHNE_01064	4.65e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GIIPGHNE_01065	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
GIIPGHNE_01066	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_01067	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_01068	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
GIIPGHNE_01069	6.76e-73	-	-	-	-	-	-	-	-
GIIPGHNE_01070	6.29e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GIIPGHNE_01071	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_01072	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_01073	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
GIIPGHNE_01074	1.65e-80	-	-	-	-	-	-	-	-
GIIPGHNE_01075	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_01076	8.6e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
GIIPGHNE_01077	5.71e-145	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_01078	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
GIIPGHNE_01079	3.39e-138	-	-	-	-	-	-	-	-
GIIPGHNE_01080	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
GIIPGHNE_01081	3.01e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GIIPGHNE_01082	1.86e-287	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
GIIPGHNE_01083	5.26e-112	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
GIIPGHNE_01084	7.04e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GIIPGHNE_01085	0.0	-	-	-	S	-	-	-	membrane
GIIPGHNE_01086	7.02e-25	-	-	-	S	-	-	-	NUDIX domain
GIIPGHNE_01087	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GIIPGHNE_01088	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
GIIPGHNE_01089	0.0	-	-	-	M	-	-	-	domain protein
GIIPGHNE_01090	2.27e-98	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
GIIPGHNE_01091	8.59e-127	-	-	-	-	-	-	-	-
GIIPGHNE_01092	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GIIPGHNE_01093	4.03e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
GIIPGHNE_01094	3.13e-225	-	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_01095	6.42e-277	-	-	-	-	-	-	-	-
GIIPGHNE_01096	3.45e-239	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
GIIPGHNE_01097	0.0	yhaN	-	-	L	-	-	-	AAA domain
GIIPGHNE_01098	7.4e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
GIIPGHNE_01099	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
GIIPGHNE_01100	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GIIPGHNE_01101	3.46e-18	-	-	-	-	-	-	-	-
GIIPGHNE_01102	2.41e-101	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
GIIPGHNE_01103	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
GIIPGHNE_01104	7.74e-131	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
GIIPGHNE_01105	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
GIIPGHNE_01106	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GIIPGHNE_01107	1.36e-70	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
GIIPGHNE_01108	1e-120	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
GIIPGHNE_01109	6.25e-138	-	-	-	-	-	-	-	-
GIIPGHNE_01110	8.81e-309	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
GIIPGHNE_01111	5.32e-120	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
GIIPGHNE_01112	1.89e-105	-	-	-	-	-	-	-	-
GIIPGHNE_01113	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
GIIPGHNE_01114	1.17e-101	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
GIIPGHNE_01117	1.79e-42	-	-	-	-	-	-	-	-
GIIPGHNE_01118	2.69e-316	dinF	-	-	V	-	-	-	MatE
GIIPGHNE_01119	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
GIIPGHNE_01120	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
GIIPGHNE_01121	1.48e-27	-	-	-	-	-	-	-	-
GIIPGHNE_01122	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
GIIPGHNE_01123	5.24e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
GIIPGHNE_01124	2.92e-113	-	-	-	-	-	-	-	-
GIIPGHNE_01125	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
GIIPGHNE_01126	1.21e-63	-	-	-	-	-	-	-	-
GIIPGHNE_01127	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
GIIPGHNE_01128	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GIIPGHNE_01129	0.0	oatA	-	-	I	-	-	-	Acyltransferase
GIIPGHNE_01130	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GIIPGHNE_01131	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GIIPGHNE_01132	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GIIPGHNE_01133	3.16e-197	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
GIIPGHNE_01134	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GIIPGHNE_01135	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GIIPGHNE_01136	1.36e-27	-	-	-	-	-	-	-	-
GIIPGHNE_01137	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01138	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
GIIPGHNE_01139	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GIIPGHNE_01140	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GIIPGHNE_01141	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GIIPGHNE_01142	2.14e-314	-	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_01143	1.46e-117	-	-	-	V	-	-	-	VanZ like family
GIIPGHNE_01144	3.88e-46	-	-	-	-	-	-	-	-
GIIPGHNE_01145	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
GIIPGHNE_01147	1.63e-257	-	-	-	-	-	-	-	-
GIIPGHNE_01148	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
GIIPGHNE_01149	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
GIIPGHNE_01150	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
GIIPGHNE_01151	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
GIIPGHNE_01152	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
GIIPGHNE_01153	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GIIPGHNE_01154	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
GIIPGHNE_01155	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
GIIPGHNE_01156	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GIIPGHNE_01157	6.45e-111	-	-	-	-	-	-	-	-
GIIPGHNE_01158	1.4e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
GIIPGHNE_01159	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GIIPGHNE_01160	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
GIIPGHNE_01161	2.16e-39	-	-	-	-	-	-	-	-
GIIPGHNE_01162	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
GIIPGHNE_01163	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GIIPGHNE_01164	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GIIPGHNE_01165	1.02e-155	-	-	-	S	-	-	-	repeat protein
GIIPGHNE_01166	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
GIIPGHNE_01167	0.0	-	-	-	N	-	-	-	domain, Protein
GIIPGHNE_01168	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
GIIPGHNE_01169	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_01170	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
GIIPGHNE_01171	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
GIIPGHNE_01172	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GIIPGHNE_01173	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
GIIPGHNE_01174	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GIIPGHNE_01175	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GIIPGHNE_01176	7.74e-47	-	-	-	-	-	-	-	-
GIIPGHNE_01177	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
GIIPGHNE_01178	5.74e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GIIPGHNE_01179	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GIIPGHNE_01180	2.65e-123	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
GIIPGHNE_01181	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
GIIPGHNE_01182	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
GIIPGHNE_01183	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GIIPGHNE_01184	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GIIPGHNE_01185	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GIIPGHNE_01186	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GIIPGHNE_01187	2.04e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GIIPGHNE_01188	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GIIPGHNE_01189	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GIIPGHNE_01190	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GIIPGHNE_01191	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
GIIPGHNE_01192	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GIIPGHNE_01193	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
GIIPGHNE_01194	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
GIIPGHNE_01195	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
GIIPGHNE_01196	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GIIPGHNE_01197	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GIIPGHNE_01198	6.87e-145	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
GIIPGHNE_01199	2.17e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GIIPGHNE_01201	3.74e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
GIIPGHNE_01202	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GIIPGHNE_01203	6.4e-54	-	-	-	-	-	-	-	-
GIIPGHNE_01204	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GIIPGHNE_01205	7.28e-42	-	-	-	-	-	-	-	-
GIIPGHNE_01206	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
GIIPGHNE_01207	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
GIIPGHNE_01209	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
GIIPGHNE_01210	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
GIIPGHNE_01211	1.08e-243	-	-	-	-	-	-	-	-
GIIPGHNE_01212	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_01213	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
GIIPGHNE_01214	4.17e-30	-	-	-	-	-	-	-	-
GIIPGHNE_01215	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
GIIPGHNE_01216	1.88e-111	-	-	-	K	-	-	-	GNAT family
GIIPGHNE_01217	8.08e-110	-	-	-	S	-	-	-	ASCH
GIIPGHNE_01218	4.3e-124	-	-	-	K	-	-	-	Cupin domain
GIIPGHNE_01219	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GIIPGHNE_01220	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_01221	3.23e-180	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_01222	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_01223	2.18e-53	-	-	-	-	-	-	-	-
GIIPGHNE_01224	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
GIIPGHNE_01225	3.55e-99	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01226	7.61e-102	-	-	-	S	ko:K02348	-	ko00000	GNAT family
GIIPGHNE_01227	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GIIPGHNE_01228	1.96e-73	-	-	-	-	-	-	-	-
GIIPGHNE_01229	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
GIIPGHNE_01230	6.88e-170	-	-	-	-	-	-	-	-
GIIPGHNE_01231	2.59e-228	-	-	-	-	-	-	-	-
GIIPGHNE_01232	1.41e-86	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
GIIPGHNE_01233	1.72e-91	-	-	-	M	-	-	-	LysM domain protein
GIIPGHNE_01234	7.98e-80	-	-	-	M	-	-	-	Lysin motif
GIIPGHNE_01235	2.75e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_01236	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_01237	4e-155	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_01238	4.32e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
GIIPGHNE_01239	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
GIIPGHNE_01240	4.07e-100	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
GIIPGHNE_01241	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
GIIPGHNE_01242	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
GIIPGHNE_01243	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
GIIPGHNE_01244	1.49e-63	-	-	-	-	-	-	-	-
GIIPGHNE_01245	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
GIIPGHNE_01246	1.45e-235	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GIIPGHNE_01247	4.78e-55	-	-	-	-	-	-	-	-
GIIPGHNE_01248	5.58e-74	-	-	-	-	-	-	-	-
GIIPGHNE_01249	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_01250	1.13e-166	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GIIPGHNE_01251	2.42e-65	-	-	-	-	-	-	-	-
GIIPGHNE_01252	1.33e-165	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
GIIPGHNE_01253	8.17e-316	hpk2	-	-	T	-	-	-	Histidine kinase
GIIPGHNE_01254	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_01255	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_01256	1.55e-55	-	-	-	-	-	-	-	-
GIIPGHNE_01257	2.92e-57	-	-	-	-	-	-	-	-
GIIPGHNE_01258	1.34e-151	-	-	-	-	-	-	-	-
GIIPGHNE_01259	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GIIPGHNE_01260	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_01261	2.98e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01262	5.52e-92	-	-	-	-	-	-	-	-
GIIPGHNE_01263	6.2e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GIIPGHNE_01264	2.6e-185	-	-	-	-	-	-	-	-
GIIPGHNE_01265	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GIIPGHNE_01266	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GIIPGHNE_01267	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GIIPGHNE_01268	2.39e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
GIIPGHNE_01269	2.21e-56	-	-	-	-	-	-	-	-
GIIPGHNE_01270	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
GIIPGHNE_01271	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
GIIPGHNE_01272	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
GIIPGHNE_01273	8.8e-210	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GIIPGHNE_01274	8.21e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
GIIPGHNE_01275	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
GIIPGHNE_01276	3.34e-244	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
GIIPGHNE_01277	1.22e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
GIIPGHNE_01278	2.92e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
GIIPGHNE_01279	5.16e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
GIIPGHNE_01280	5.34e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
GIIPGHNE_01281	6.14e-53	-	-	-	-	-	-	-	-
GIIPGHNE_01282	1.36e-289	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_01283	1.89e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
GIIPGHNE_01284	1.28e-126	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
GIIPGHNE_01285	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
GIIPGHNE_01286	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
GIIPGHNE_01287	2.98e-90	-	-	-	-	-	-	-	-
GIIPGHNE_01288	1.22e-125	-	-	-	-	-	-	-	-
GIIPGHNE_01289	9.83e-66	-	-	-	-	-	-	-	-
GIIPGHNE_01290	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GIIPGHNE_01291	8.49e-112	-	-	-	-	-	-	-	-
GIIPGHNE_01292	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
GIIPGHNE_01293	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_01294	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
GIIPGHNE_01295	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GIIPGHNE_01296	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GIIPGHNE_01298	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GIIPGHNE_01299	1.2e-91	-	-	-	-	-	-	-	-
GIIPGHNE_01300	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GIIPGHNE_01301	5.3e-202	dkgB	-	-	S	-	-	-	reductase
GIIPGHNE_01302	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
GIIPGHNE_01303	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
GIIPGHNE_01304	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GIIPGHNE_01305	1.5e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
GIIPGHNE_01306	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
GIIPGHNE_01307	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GIIPGHNE_01308	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GIIPGHNE_01309	3.81e-18	-	-	-	-	-	-	-	-
GIIPGHNE_01310	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GIIPGHNE_01311	3.91e-211	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
GIIPGHNE_01312	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
GIIPGHNE_01313	6.33e-46	-	-	-	-	-	-	-	-
GIIPGHNE_01314	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
GIIPGHNE_01315	6.79e-146	-	-	-	-	-	-	-	-
GIIPGHNE_01316	2.4e-128	-	-	-	D	-	-	-	Relaxase/Mobilisation nuclease domain
GIIPGHNE_01317	2.01e-22	mobC	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
GIIPGHNE_01319	4.4e-105	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
GIIPGHNE_01321	6.56e-48	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
GIIPGHNE_01322	6.65e-207	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
GIIPGHNE_01323	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
GIIPGHNE_01325	4.76e-106	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_01326	1.88e-43	-	-	-	-	-	-	-	-
GIIPGHNE_01327	2.93e-11	-	-	-	-	-	-	-	-
GIIPGHNE_01328	6.93e-194	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
GIIPGHNE_01329	3.57e-47	-	-	-	-	-	-	-	-
GIIPGHNE_01330	6.45e-230	repA	-	-	S	-	-	-	Replication initiator protein A
GIIPGHNE_01331	8.09e-93	-	-	-	Q	-	-	-	Methyltransferase
GIIPGHNE_01332	1.35e-50	-	-	-	-	-	-	-	-
GIIPGHNE_01333	7.49e-32	-	-	-	-	-	-	-	-
GIIPGHNE_01334	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
GIIPGHNE_01335	9.69e-66	-	-	-	-	-	-	-	-
GIIPGHNE_01336	6.62e-133	-	-	-	-	-	-	-	-
GIIPGHNE_01337	3.51e-65	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
GIIPGHNE_01338	8.94e-70	-	-	-	-	-	-	-	-
GIIPGHNE_01339	1.34e-153	-	-	-	-	-	-	-	-
GIIPGHNE_01340	0.0	-	-	-	U	-	-	-	AAA-like domain
GIIPGHNE_01341	0.0	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
GIIPGHNE_01342	3.93e-270	-	-	-	M	-	-	-	CHAP domain
GIIPGHNE_01343	3.32e-117	-	-	-	-	-	-	-	-
GIIPGHNE_01344	6.12e-87	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
GIIPGHNE_01345	2.4e-107	-	-	-	-	-	-	-	-
GIIPGHNE_01346	0.0	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
GIIPGHNE_01347	8.57e-80	-	-	-	-	-	-	-	-
GIIPGHNE_01348	2.81e-197	-	-	-	-	-	-	-	-
GIIPGHNE_01349	3.31e-84	-	-	-	-	-	-	-	-
GIIPGHNE_01350	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
GIIPGHNE_01351	2.16e-43	-	-	-	-	-	-	-	-
GIIPGHNE_01352	6.95e-245	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
GIIPGHNE_01353	4.64e-19	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_01354	1.41e-243	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
GIIPGHNE_01355	2.36e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_01356	3.27e-170	-	-	-	S	-	-	-	KR domain
GIIPGHNE_01357	5.17e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
GIIPGHNE_01358	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
GIIPGHNE_01359	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
GIIPGHNE_01360	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GIIPGHNE_01361	5.35e-216	-	-	-	GM	-	-	-	NmrA-like family
GIIPGHNE_01362	3.75e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_01363	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GIIPGHNE_01364	6.58e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
GIIPGHNE_01365	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GIIPGHNE_01366	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
GIIPGHNE_01367	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_01368	5.5e-93	-	-	-	-	-	-	-	-
GIIPGHNE_01369	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
GIIPGHNE_01370	2.42e-115	-	-	-	-	-	-	-	-
GIIPGHNE_01371	1.91e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GIIPGHNE_01372	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GIIPGHNE_01373	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GIIPGHNE_01374	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GIIPGHNE_01375	8.49e-60	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GIIPGHNE_01376	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GIIPGHNE_01377	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
GIIPGHNE_01378	1.49e-315	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GIIPGHNE_01379	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GIIPGHNE_01380	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
GIIPGHNE_01381	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GIIPGHNE_01382	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
GIIPGHNE_01383	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GIIPGHNE_01384	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GIIPGHNE_01385	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GIIPGHNE_01386	2.57e-118	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
GIIPGHNE_01387	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
GIIPGHNE_01388	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GIIPGHNE_01389	4.71e-124	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
GIIPGHNE_01390	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
GIIPGHNE_01391	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GIIPGHNE_01392	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GIIPGHNE_01393	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
GIIPGHNE_01394	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GIIPGHNE_01395	1.6e-96	-	-	-	-	-	-	-	-
GIIPGHNE_01396	1.51e-104	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_01397	1.27e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GIIPGHNE_01398	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
GIIPGHNE_01399	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
GIIPGHNE_01400	1.16e-63	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
GIIPGHNE_01401	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
GIIPGHNE_01402	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GIIPGHNE_01403	1.48e-223	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
GIIPGHNE_01404	8.44e-240	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
GIIPGHNE_01405	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
GIIPGHNE_01406	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
GIIPGHNE_01407	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
GIIPGHNE_01408	2.16e-111	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
GIIPGHNE_01410	7.75e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
GIIPGHNE_01411	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GIIPGHNE_01412	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GIIPGHNE_01413	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GIIPGHNE_01414	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GIIPGHNE_01415	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
GIIPGHNE_01416	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GIIPGHNE_01417	3.3e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
GIIPGHNE_01418	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
GIIPGHNE_01419	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GIIPGHNE_01420	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
GIIPGHNE_01421	1.11e-84	-	-	-	-	-	-	-	-
GIIPGHNE_01422	0.000119	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GIIPGHNE_01423	2.04e-173	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
GIIPGHNE_01425	2.59e-127	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
GIIPGHNE_01426	7.97e-41	-	-	-	-	-	-	-	-
GIIPGHNE_01427	1.24e-49	-	-	-	-	-	-	-	-
GIIPGHNE_01428	3.68e-295	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
GIIPGHNE_01429	2.04e-36	-	-	-	-	-	-	-	-
GIIPGHNE_01430	1.99e-120	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
GIIPGHNE_01431	1.24e-120	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
GIIPGHNE_01434	3.58e-06	-	-	-	S	-	-	-	COG0433 Predicted ATPase
GIIPGHNE_01435	2.02e-119	-	-	-	S	-	-	-	COG0433 Predicted ATPase
GIIPGHNE_01437	1.08e-121	-	-	-	M	-	-	-	CHAP domain
GIIPGHNE_01442	7.73e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
GIIPGHNE_01453	2.12e-14	XK27_07075	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_01455	1.34e-34	-	-	-	-	-	-	-	-
GIIPGHNE_01456	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	C-terminal repeat of topoisomerase
GIIPGHNE_01461	1.1e-155	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
GIIPGHNE_01464	4.84e-35	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
GIIPGHNE_01469	1.98e-280	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
GIIPGHNE_01470	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
GIIPGHNE_01471	1.64e-295	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
GIIPGHNE_01472	2.06e-73	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
GIIPGHNE_01473	4.78e-191	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
GIIPGHNE_01474	2.24e-103	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
GIIPGHNE_01475	3.27e-103	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
GIIPGHNE_01476	1.15e-173	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GIIPGHNE_01477	7.43e-120	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
GIIPGHNE_01478	9.5e-69	-	-	-	L	-	-	-	Integrase core domain
GIIPGHNE_01479	1.57e-70	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GIIPGHNE_01482	1.92e-112	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GIIPGHNE_01483	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
GIIPGHNE_01484	3.39e-32	-	-	-	L	-	-	-	Integrase
GIIPGHNE_01485	1.8e-39	-	-	-	L	-	-	-	Integrase
GIIPGHNE_01486	7.03e-39	-	-	-	S	-	-	-	Enterocin A Immunity
GIIPGHNE_01487	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GIIPGHNE_01488	2.42e-210	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GIIPGHNE_01489	7.73e-178	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
GIIPGHNE_01490	6.62e-197	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
GIIPGHNE_01491	8.34e-91	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
GIIPGHNE_01492	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
GIIPGHNE_01493	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GIIPGHNE_01494	4.81e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_01495	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GIIPGHNE_01496	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GIIPGHNE_01497	0.0	ydaO	-	-	E	-	-	-	amino acid
GIIPGHNE_01498	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
GIIPGHNE_01499	1.09e-197	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
GIIPGHNE_01500	1.51e-148	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
GIIPGHNE_01501	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
GIIPGHNE_01502	6.92e-152	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
GIIPGHNE_01503	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GIIPGHNE_01504	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GIIPGHNE_01505	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GIIPGHNE_01506	1.5e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
GIIPGHNE_01507	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
GIIPGHNE_01508	8.9e-317	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GIIPGHNE_01509	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
GIIPGHNE_01510	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
GIIPGHNE_01511	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
GIIPGHNE_01512	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GIIPGHNE_01513	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GIIPGHNE_01514	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
GIIPGHNE_01515	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
GIIPGHNE_01516	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
GIIPGHNE_01517	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GIIPGHNE_01518	6.26e-213	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GIIPGHNE_01519	2.82e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
GIIPGHNE_01520	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GIIPGHNE_01521	3.69e-159	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
GIIPGHNE_01523	7.53e-209	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01524	2.95e-207	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
GIIPGHNE_01525	8.21e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
GIIPGHNE_01526	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
GIIPGHNE_01527	0.0	ycaM	-	-	E	-	-	-	amino acid
GIIPGHNE_01528	4.23e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
GIIPGHNE_01529	4.3e-44	-	-	-	-	-	-	-	-
GIIPGHNE_01530	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
GIIPGHNE_01531	2.47e-68	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
GIIPGHNE_01532	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
GIIPGHNE_01533	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GIIPGHNE_01534	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
GIIPGHNE_01535	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
GIIPGHNE_01536	1.96e-224	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
GIIPGHNE_01537	3.98e-204	-	-	-	EG	-	-	-	EamA-like transporter family
GIIPGHNE_01538	7.17e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GIIPGHNE_01539	5.06e-196	-	-	-	S	-	-	-	hydrolase
GIIPGHNE_01540	7.63e-107	-	-	-	-	-	-	-	-
GIIPGHNE_01541	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
GIIPGHNE_01542	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
GIIPGHNE_01543	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
GIIPGHNE_01544	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GIIPGHNE_01545	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
GIIPGHNE_01546	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_01547	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_01548	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
GIIPGHNE_01549	3.53e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
GIIPGHNE_01550	8e-233	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_01551	6.09e-152	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01552	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GIIPGHNE_01553	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
GIIPGHNE_01554	1.66e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
GIIPGHNE_01555	1.73e-291	-	-	-	S	-	-	-	Sterol carrier protein domain
GIIPGHNE_01556	6.01e-270	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
GIIPGHNE_01557	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
GIIPGHNE_01558	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
GIIPGHNE_01559	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
GIIPGHNE_01560	5.38e-131	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
GIIPGHNE_01561	1.76e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
GIIPGHNE_01562	1.88e-39	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
GIIPGHNE_01563	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GIIPGHNE_01564	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
GIIPGHNE_01565	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
GIIPGHNE_01567	1.21e-69	-	-	-	-	-	-	-	-
GIIPGHNE_01568	1.52e-151	-	-	-	-	-	-	-	-
GIIPGHNE_01569	3.32e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
GIIPGHNE_01570	1.75e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
GIIPGHNE_01571	4.79e-13	-	-	-	-	-	-	-	-
GIIPGHNE_01572	4.87e-66	-	-	-	-	-	-	-	-
GIIPGHNE_01573	2.92e-113	-	-	-	-	-	-	-	-
GIIPGHNE_01574	4.69e-94	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
GIIPGHNE_01575	1.08e-47	-	-	-	-	-	-	-	-
GIIPGHNE_01576	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
GIIPGHNE_01577	3.41e-190	-	-	-	-	-	-	-	-
GIIPGHNE_01578	7.57e-210	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_01579	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
GIIPGHNE_01580	3.92e-55	-	-	-	-	-	-	-	-
GIIPGHNE_01581	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
GIIPGHNE_01582	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_01583	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
GIIPGHNE_01584	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_01585	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
GIIPGHNE_01586	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GIIPGHNE_01587	4.94e-244	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
GIIPGHNE_01588	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
GIIPGHNE_01589	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
GIIPGHNE_01590	5.36e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GIIPGHNE_01591	1.17e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GIIPGHNE_01592	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
GIIPGHNE_01593	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GIIPGHNE_01594	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GIIPGHNE_01595	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GIIPGHNE_01596	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GIIPGHNE_01597	3.61e-244	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
GIIPGHNE_01598	1.08e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GIIPGHNE_01599	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
GIIPGHNE_01600	5.47e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
GIIPGHNE_01601	1.2e-162	-	-	-	E	-	-	-	Methionine synthase
GIIPGHNE_01602	1.61e-242	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
GIIPGHNE_01603	4.85e-45	mobC	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
GIIPGHNE_01605	2.78e-86	-	-	-	-	-	-	-	-
GIIPGHNE_01607	9.63e-154	-	-	-	-	-	-	-	-
GIIPGHNE_01608	3.99e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
GIIPGHNE_01609	1.58e-66	-	-	-	-	-	-	-	-
GIIPGHNE_01610	3.74e-123	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
GIIPGHNE_01611	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
GIIPGHNE_01612	7.71e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GIIPGHNE_01613	1.05e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
GIIPGHNE_01614	2.07e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
GIIPGHNE_01615	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
GIIPGHNE_01616	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
GIIPGHNE_01617	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GIIPGHNE_01618	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GIIPGHNE_01619	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
GIIPGHNE_01620	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
GIIPGHNE_01621	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
GIIPGHNE_01622	2.44e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
GIIPGHNE_01623	5.09e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
GIIPGHNE_01624	1.63e-285	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GIIPGHNE_01625	4.31e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_01627	5.67e-102	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
GIIPGHNE_01628	1.6e-55	-	-	-	-	-	-	-	-
GIIPGHNE_01629	1.15e-05	-	-	-	-	-	-	-	-
GIIPGHNE_01631	1.84e-61	-	-	-	-	-	-	-	-
GIIPGHNE_01632	6.9e-41	-	-	-	-	-	-	-	-
GIIPGHNE_01633	3.1e-172	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
GIIPGHNE_01634	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
GIIPGHNE_01635	3.74e-82	-	-	-	-	-	-	-	-
GIIPGHNE_01636	2.71e-37	-	-	-	-	-	-	-	-
GIIPGHNE_01637	1.45e-67	-	-	-	-	-	-	-	-
GIIPGHNE_01639	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
GIIPGHNE_01640	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
GIIPGHNE_01641	2.55e-65	-	-	-	-	-	-	-	-
GIIPGHNE_01642	8.44e-34	-	-	-	-	-	-	-	-
GIIPGHNE_01643	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
GIIPGHNE_01644	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
GIIPGHNE_01645	4.26e-54	-	-	-	-	-	-	-	-
GIIPGHNE_01646	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
GIIPGHNE_01647	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
GIIPGHNE_01648	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
GIIPGHNE_01649	1.47e-144	-	-	-	S	-	-	-	VIT family
GIIPGHNE_01650	2.66e-155	-	-	-	S	-	-	-	membrane
GIIPGHNE_01651	1.9e-202	-	-	-	EG	-	-	-	EamA-like transporter family
GIIPGHNE_01652	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
GIIPGHNE_01653	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
GIIPGHNE_01654	4.79e-21	-	-	-	-	-	-	-	-
GIIPGHNE_01655	2.27e-74	-	-	-	-	-	-	-	-
GIIPGHNE_01656	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GIIPGHNE_01657	1.36e-112	-	-	-	-	-	-	-	-
GIIPGHNE_01658	1.73e-81	-	-	-	-	-	-	-	-
GIIPGHNE_01659	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
GIIPGHNE_01660	1.7e-70	-	-	-	-	-	-	-	-
GIIPGHNE_01661	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
GIIPGHNE_01662	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
GIIPGHNE_01663	7.45e-87	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
GIIPGHNE_01664	1.36e-209	-	-	-	GM	-	-	-	NmrA-like family
GIIPGHNE_01665	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
GIIPGHNE_01666	1.67e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_01667	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GIIPGHNE_01668	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GIIPGHNE_01669	5.92e-35	-	-	-	S	-	-	-	Belongs to the LOG family
GIIPGHNE_01670	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
GIIPGHNE_01671	2.03e-84	-	-	-	-	-	-	-	-
GIIPGHNE_01672	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
GIIPGHNE_01673	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_01674	1.88e-53	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
GIIPGHNE_01675	2.62e-121	-	-	-	-	-	-	-	-
GIIPGHNE_01676	1.46e-198	-	-	-	T	-	-	-	EAL domain
GIIPGHNE_01677	9.5e-208	-	-	-	GM	-	-	-	NmrA-like family
GIIPGHNE_01678	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
GIIPGHNE_01679	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
GIIPGHNE_01680	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
GIIPGHNE_01681	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GIIPGHNE_01682	1e-219	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
GIIPGHNE_01683	2.78e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GIIPGHNE_01684	9.63e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GIIPGHNE_01685	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GIIPGHNE_01686	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GIIPGHNE_01687	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GIIPGHNE_01688	5.46e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GIIPGHNE_01689	2.52e-213	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
GIIPGHNE_01690	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GIIPGHNE_01691	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
GIIPGHNE_01692	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
GIIPGHNE_01693	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
GIIPGHNE_01694	8.13e-208	mleR	-	-	K	-	-	-	LysR family
GIIPGHNE_01695	1.41e-167	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GIIPGHNE_01696	3.59e-26	-	-	-	-	-	-	-	-
GIIPGHNE_01697	4.34e-203	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GIIPGHNE_01698	3.4e-276	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GIIPGHNE_01699	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
GIIPGHNE_01700	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GIIPGHNE_01701	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
GIIPGHNE_01702	6.01e-218	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
GIIPGHNE_01703	1.64e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_01704	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_01705	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GIIPGHNE_01706	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
GIIPGHNE_01707	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
GIIPGHNE_01708	2.97e-76	-	-	-	-	-	-	-	-
GIIPGHNE_01709	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GIIPGHNE_01710	1.55e-79	-	-	-	-	-	-	-	-
GIIPGHNE_01711	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
GIIPGHNE_01712	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
GIIPGHNE_01713	1.97e-150	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GIIPGHNE_01714	1.01e-177	-	-	-	-	-	-	-	-
GIIPGHNE_01715	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GIIPGHNE_01716	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01717	1.07e-204	-	-	-	S	-	-	-	Putative esterase
GIIPGHNE_01718	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
GIIPGHNE_01719	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
GIIPGHNE_01720	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
GIIPGHNE_01721	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
GIIPGHNE_01722	8.5e-98	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
GIIPGHNE_01723	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
GIIPGHNE_01724	3.77e-24	-	-	-	-	-	-	-	-
GIIPGHNE_01725	5.04e-203	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
GIIPGHNE_01726	7.2e-103	uspA3	-	-	T	-	-	-	universal stress protein
GIIPGHNE_01727	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
GIIPGHNE_01728	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
GIIPGHNE_01729	4.15e-78	-	-	-	-	-	-	-	-
GIIPGHNE_01730	4.05e-98	-	-	-	-	-	-	-	-
GIIPGHNE_01731	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
GIIPGHNE_01732	3.04e-62	-	-	-	-	-	-	-	-
GIIPGHNE_01733	3.89e-62	-	-	-	-	-	-	-	-
GIIPGHNE_01734	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
GIIPGHNE_01735	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
GIIPGHNE_01736	1.97e-185	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
GIIPGHNE_01737	1e-89	-	-	-	-	-	-	-	-
GIIPGHNE_01738	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GIIPGHNE_01739	1.23e-75	-	-	-	-	-	-	-	-
GIIPGHNE_01740	7.58e-210	-	-	-	-	-	-	-	-
GIIPGHNE_01741	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01742	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
GIIPGHNE_01743	2.67e-222	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
GIIPGHNE_01744	1.2e-59	-	-	-	S	-	-	-	Enterocin A Immunity
GIIPGHNE_01745	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
GIIPGHNE_01746	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_01747	4.4e-171	-	-	-	-	-	-	-	-
GIIPGHNE_01748	7.71e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
GIIPGHNE_01749	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GIIPGHNE_01750	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GIIPGHNE_01751	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
GIIPGHNE_01752	5e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
GIIPGHNE_01753	4.34e-202	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GIIPGHNE_01754	2.89e-224	ccpB	-	-	K	-	-	-	lacI family
GIIPGHNE_01755	1.75e-181	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GIIPGHNE_01756	1.81e-160	mipB	2.2.1.2	-	H	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
GIIPGHNE_01757	3.53e-227	-	-	-	K	-	-	-	sugar-binding domain protein
GIIPGHNE_01758	0.0	pflD	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
GIIPGHNE_01759	1.18e-172	rdrA	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
GIIPGHNE_01760	2.08e-199	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIIPGHNE_01761	3.03e-230	-	-	-	GK	-	-	-	ROK family
GIIPGHNE_01762	7.45e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GIIPGHNE_01763	1.64e-207	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GIIPGHNE_01764	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
GIIPGHNE_01765	1.05e-127	-	-	-	C	-	-	-	Nitroreductase family
GIIPGHNE_01766	2.02e-215	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
GIIPGHNE_01767	7.72e-28	-	-	-	-	-	-	-	-
GIIPGHNE_01768	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
GIIPGHNE_01769	1.45e-102	-	-	-	T	-	-	-	Universal stress protein family
GIIPGHNE_01770	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
GIIPGHNE_01771	9.08e-134	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
GIIPGHNE_01772	1.13e-182	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
GIIPGHNE_01773	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_01774	6.95e-204	degV1	-	-	S	-	-	-	DegV family
GIIPGHNE_01775	2.89e-80	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
GIIPGHNE_01776	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
GIIPGHNE_01778	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GIIPGHNE_01779	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_01781	1.5e-209	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
GIIPGHNE_01782	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
GIIPGHNE_01783	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GIIPGHNE_01784	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GIIPGHNE_01785	2.37e-173	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
GIIPGHNE_01786	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GIIPGHNE_01787	3.08e-74	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GIIPGHNE_01788	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GIIPGHNE_01789	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GIIPGHNE_01790	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
GIIPGHNE_01791	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GIIPGHNE_01792	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GIIPGHNE_01793	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GIIPGHNE_01794	2.6e-154	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
GIIPGHNE_01795	9.31e-97	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
GIIPGHNE_01796	4.53e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
GIIPGHNE_01797	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01798	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
GIIPGHNE_01799	3.1e-169	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GIIPGHNE_01800	9.83e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_01801	1.87e-117	-	-	-	F	-	-	-	NUDIX domain
GIIPGHNE_01803	2.31e-174	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
GIIPGHNE_01804	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
GIIPGHNE_01805	3.22e-53	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
GIIPGHNE_01806	7.94e-86	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
GIIPGHNE_01808	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
GIIPGHNE_01809	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
GIIPGHNE_01810	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GIIPGHNE_01811	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GIIPGHNE_01812	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
GIIPGHNE_01813	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GIIPGHNE_01814	5.62e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GIIPGHNE_01815	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GIIPGHNE_01816	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
GIIPGHNE_01817	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
GIIPGHNE_01818	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
GIIPGHNE_01819	1.47e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
GIIPGHNE_01820	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
GIIPGHNE_01821	2.76e-248	-	-	-	-	-	-	-	-
GIIPGHNE_01822	9.39e-157	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GIIPGHNE_01823	8.46e-141	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
GIIPGHNE_01824	8.01e-231	-	-	-	V	-	-	-	LD-carboxypeptidase
GIIPGHNE_01825	2.13e-312	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
GIIPGHNE_01826	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_01827	1.03e-117	mccF	-	-	V	-	-	-	LD-carboxypeptidase
GIIPGHNE_01828	5.46e-96	mccF	-	-	V	-	-	-	LD-carboxypeptidase
GIIPGHNE_01829	8.61e-310	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
GIIPGHNE_01830	7.86e-96	-	-	-	S	-	-	-	SnoaL-like domain
GIIPGHNE_01831	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
GIIPGHNE_01832	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
GIIPGHNE_01834	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GIIPGHNE_01835	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
GIIPGHNE_01836	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GIIPGHNE_01837	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
GIIPGHNE_01838	4.64e-228	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
GIIPGHNE_01839	1.98e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GIIPGHNE_01840	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_01841	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
GIIPGHNE_01842	3.19e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GIIPGHNE_01843	1.41e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_01844	9.85e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GIIPGHNE_01846	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
GIIPGHNE_01847	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
GIIPGHNE_01848	2.55e-288	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
GIIPGHNE_01849	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
GIIPGHNE_01850	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
GIIPGHNE_01851	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
GIIPGHNE_01852	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
GIIPGHNE_01853	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
GIIPGHNE_01854	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GIIPGHNE_01855	9.62e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
GIIPGHNE_01856	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
GIIPGHNE_01857	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
GIIPGHNE_01859	4.17e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
GIIPGHNE_01860	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
GIIPGHNE_01861	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GIIPGHNE_01862	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
GIIPGHNE_01863	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GIIPGHNE_01864	3.23e-58	-	-	-	-	-	-	-	-
GIIPGHNE_01865	1.52e-67	-	-	-	-	-	-	-	-
GIIPGHNE_01866	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
GIIPGHNE_01867	6.03e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
GIIPGHNE_01868	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GIIPGHNE_01869	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
GIIPGHNE_01870	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GIIPGHNE_01871	1.06e-53	-	-	-	-	-	-	-	-
GIIPGHNE_01872	4e-40	-	-	-	S	-	-	-	CsbD-like
GIIPGHNE_01873	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
GIIPGHNE_01874	1.66e-20	-	-	-	-	-	-	-	-
GIIPGHNE_01875	1.51e-48	-	-	-	-	-	-	-	-
GIIPGHNE_01876	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
GIIPGHNE_01877	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
GIIPGHNE_01878	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GIIPGHNE_01879	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
GIIPGHNE_01880	2.05e-55	-	-	-	-	-	-	-	-
GIIPGHNE_01881	1.45e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
GIIPGHNE_01882	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
GIIPGHNE_01883	2.29e-274	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
GIIPGHNE_01884	2.02e-39	-	-	-	-	-	-	-	-
GIIPGHNE_01885	4.97e-70	-	-	-	-	-	-	-	-
GIIPGHNE_01886	3.02e-07	-	-	-	K	-	-	-	transcriptional regulator
GIIPGHNE_01887	1e-112	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
GIIPGHNE_01888	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
GIIPGHNE_01889	0.0	-	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_01890	8.6e-121	-	-	-	K	-	-	-	transcriptional regulator
GIIPGHNE_01891	1.82e-77	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
GIIPGHNE_01892	8.8e-294	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
GIIPGHNE_01893	1.69e-180	-	-	-	-	-	-	-	-
GIIPGHNE_01894	4.07e-05	-	-	-	-	-	-	-	-
GIIPGHNE_01895	5.9e-186	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
GIIPGHNE_01896	1.67e-54	-	-	-	-	-	-	-	-
GIIPGHNE_01897	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_01898	2.21e-188	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
GIIPGHNE_01899	1.76e-233	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
GIIPGHNE_01900	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
GIIPGHNE_01901	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
GIIPGHNE_01902	2.14e-157	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
GIIPGHNE_01903	1.37e-177	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
GIIPGHNE_01904	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
GIIPGHNE_01905	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GIIPGHNE_01906	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
GIIPGHNE_01907	8.65e-228	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
GIIPGHNE_01908	1.87e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GIIPGHNE_01909	4.82e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GIIPGHNE_01910	1.09e-142	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GIIPGHNE_01911	4.15e-261	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
GIIPGHNE_01912	7.45e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
GIIPGHNE_01913	0.0	-	-	-	L	-	-	-	HIRAN domain
GIIPGHNE_01914	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
GIIPGHNE_01915	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GIIPGHNE_01916	1e-156	-	-	-	-	-	-	-	-
GIIPGHNE_01917	3.43e-190	-	-	-	I	-	-	-	Alpha/beta hydrolase family
GIIPGHNE_01918	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GIIPGHNE_01919	5.46e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
GIIPGHNE_01920	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
GIIPGHNE_01921	1.41e-141	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
GIIPGHNE_01922	1.27e-98	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_01923	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GIIPGHNE_01924	2.16e-103	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
GIIPGHNE_01925	4.46e-88	-	-	-	K	-	-	-	LytTr DNA-binding domain
GIIPGHNE_01926	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
GIIPGHNE_01927	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GIIPGHNE_01928	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
GIIPGHNE_01930	2.32e-199	morA	-	-	S	-	-	-	reductase
GIIPGHNE_01931	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
GIIPGHNE_01932	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
GIIPGHNE_01933	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GIIPGHNE_01934	2.65e-116	-	-	-	-	-	-	-	-
GIIPGHNE_01935	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_01936	6.49e-268	-	-	-	C	-	-	-	Oxidoreductase
GIIPGHNE_01937	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
GIIPGHNE_01938	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_01939	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
GIIPGHNE_01940	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
GIIPGHNE_01941	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
GIIPGHNE_01942	2.47e-179	-	-	-	-	-	-	-	-
GIIPGHNE_01943	1.57e-191	-	-	-	-	-	-	-	-
GIIPGHNE_01944	3.37e-115	-	-	-	-	-	-	-	-
GIIPGHNE_01945	7.14e-185	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
GIIPGHNE_01946	4.24e-218	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_01947	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
GIIPGHNE_01948	9.37e-150	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
GIIPGHNE_01949	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
GIIPGHNE_01950	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
GIIPGHNE_01951	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
GIIPGHNE_01952	3.82e-176	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
GIIPGHNE_01953	5.78e-144	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
GIIPGHNE_01954	2.72e-202	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
GIIPGHNE_01955	3.76e-157	-	-	-	G	-	-	-	Glycogen debranching enzyme, glucanotransferase domain
GIIPGHNE_01956	1.89e-225	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GIIPGHNE_01957	9.4e-172	-	-	-	U	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_01958	8.34e-155	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_01959	4.36e-32	-	-	-	-	-	-	-	-
GIIPGHNE_01960	6.31e-224	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GIIPGHNE_01961	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
GIIPGHNE_01962	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
GIIPGHNE_01963	1.07e-197	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
GIIPGHNE_01964	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
GIIPGHNE_01965	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
GIIPGHNE_01966	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
GIIPGHNE_01967	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GIIPGHNE_01968	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
GIIPGHNE_01969	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
GIIPGHNE_01970	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GIIPGHNE_01971	4.52e-208	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
GIIPGHNE_01972	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GIIPGHNE_01973	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GIIPGHNE_01974	5.99e-213	mleR	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_01975	0.0	-	-	-	M	-	-	-	domain protein
GIIPGHNE_01977	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
GIIPGHNE_01978	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
GIIPGHNE_01979	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
GIIPGHNE_01980	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
GIIPGHNE_01981	1.45e-278	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GIIPGHNE_01982	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GIIPGHNE_01983	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
GIIPGHNE_01984	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GIIPGHNE_01985	4.91e-265	yacL	-	-	S	-	-	-	domain protein
GIIPGHNE_01986	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GIIPGHNE_01987	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GIIPGHNE_01988	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GIIPGHNE_01989	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GIIPGHNE_01990	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
GIIPGHNE_01991	4.58e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
GIIPGHNE_01992	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GIIPGHNE_01993	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GIIPGHNE_01994	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
GIIPGHNE_01995	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_01996	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GIIPGHNE_01997	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GIIPGHNE_01998	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GIIPGHNE_01999	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GIIPGHNE_02000	1.13e-223	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
GIIPGHNE_02001	4.82e-86	-	-	-	L	-	-	-	nuclease
GIIPGHNE_02002	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GIIPGHNE_02003	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
GIIPGHNE_02004	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIIPGHNE_02005	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GIIPGHNE_02006	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
GIIPGHNE_02007	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
GIIPGHNE_02008	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GIIPGHNE_02009	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GIIPGHNE_02010	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GIIPGHNE_02011	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GIIPGHNE_02012	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
GIIPGHNE_02013	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GIIPGHNE_02014	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
GIIPGHNE_02015	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GIIPGHNE_02016	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
GIIPGHNE_02017	2.64e-213	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GIIPGHNE_02018	9.1e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
GIIPGHNE_02019	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GIIPGHNE_02020	9.25e-271	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
GIIPGHNE_02021	2.8e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
GIIPGHNE_02022	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_02023	8.86e-176	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
GIIPGHNE_02024	3.8e-176	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GIIPGHNE_02025	2.33e-240	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
GIIPGHNE_02026	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
GIIPGHNE_02027	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
GIIPGHNE_02028	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GIIPGHNE_02029	3.48e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GIIPGHNE_02030	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GIIPGHNE_02031	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
GIIPGHNE_02032	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
GIIPGHNE_02033	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
GIIPGHNE_02034	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
GIIPGHNE_02035	6.07e-33	-	-	-	-	-	-	-	-
GIIPGHNE_02036	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
GIIPGHNE_02037	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
GIIPGHNE_02038	9.09e-213	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
GIIPGHNE_02039	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
GIIPGHNE_02040	4.39e-213	mleR	-	-	K	-	-	-	LysR family
GIIPGHNE_02041	4.54e-207	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
GIIPGHNE_02042	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GIIPGHNE_02043	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GIIPGHNE_02044	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GIIPGHNE_02045	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GIIPGHNE_02046	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GIIPGHNE_02047	1.84e-189	-	-	-	-	-	-	-	-
GIIPGHNE_02048	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
GIIPGHNE_02049	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
GIIPGHNE_02050	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
GIIPGHNE_02051	2.11e-273	-	-	-	J	-	-	-	translation release factor activity
GIIPGHNE_02052	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
GIIPGHNE_02053	1.79e-305	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GIIPGHNE_02054	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GIIPGHNE_02055	2.41e-37	-	-	-	-	-	-	-	-
GIIPGHNE_02056	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
GIIPGHNE_02057	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GIIPGHNE_02058	4.34e-158	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
GIIPGHNE_02059	1.87e-289	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
GIIPGHNE_02060	2.38e-311	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GIIPGHNE_02061	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GIIPGHNE_02062	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GIIPGHNE_02063	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
GIIPGHNE_02064	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
GIIPGHNE_02065	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
GIIPGHNE_02066	1.19e-190	yxeH	-	-	S	-	-	-	hydrolase
GIIPGHNE_02067	7.12e-178	-	-	-	-	-	-	-	-
GIIPGHNE_02068	1.82e-232	-	-	-	S	-	-	-	DUF218 domain
GIIPGHNE_02069	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GIIPGHNE_02070	4.03e-193	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
GIIPGHNE_02071	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GIIPGHNE_02072	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
GIIPGHNE_02073	5.3e-49	-	-	-	-	-	-	-	-
GIIPGHNE_02074	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
GIIPGHNE_02076	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
GIIPGHNE_02077	3.28e-165	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GIIPGHNE_02078	1.23e-226	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
GIIPGHNE_02079	1.07e-207	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GIIPGHNE_02080	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
GIIPGHNE_02081	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GIIPGHNE_02082	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GIIPGHNE_02083	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
GIIPGHNE_02085	1.01e-133	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
GIIPGHNE_02086	1.22e-271	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
GIIPGHNE_02088	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
GIIPGHNE_02089	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	membrane
GIIPGHNE_02090	1.74e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
GIIPGHNE_02091	1.9e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GIIPGHNE_02092	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
GIIPGHNE_02093	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GIIPGHNE_02094	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GIIPGHNE_02095	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GIIPGHNE_02096	1.51e-140	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GIIPGHNE_02097	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
GIIPGHNE_02098	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GIIPGHNE_02099	1.39e-150	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GIIPGHNE_02100	1.39e-276	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GIIPGHNE_02101	1.12e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
GIIPGHNE_02102	2.51e-281	ysaA	-	-	V	-	-	-	RDD family
GIIPGHNE_02103	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
GIIPGHNE_02104	1.71e-67	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
GIIPGHNE_02105	2.54e-17	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
GIIPGHNE_02106	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GIIPGHNE_02107	5.48e-236	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GIIPGHNE_02108	1.45e-46	-	-	-	-	-	-	-	-
GIIPGHNE_02109	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
GIIPGHNE_02110	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
GIIPGHNE_02111	0.0	-	-	-	M	-	-	-	domain protein
GIIPGHNE_02112	7.35e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_02113	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GIIPGHNE_02114	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
GIIPGHNE_02115	6.65e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
GIIPGHNE_02116	4.14e-181	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_02117	0.0	nox	-	-	C	-	-	-	NADH oxidase
GIIPGHNE_02118	2.19e-166	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GIIPGHNE_02119	1.63e-23	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
GIIPGHNE_02120	9.98e-310	-	-	-	-	-	-	-	-
GIIPGHNE_02121	1.12e-254	-	-	-	S	-	-	-	Protein conserved in bacteria
GIIPGHNE_02122	6.44e-276	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
GIIPGHNE_02123	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
GIIPGHNE_02124	3.07e-169	-	-	-	T	-	-	-	diguanylate cyclase activity
GIIPGHNE_02125	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GIIPGHNE_02126	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
GIIPGHNE_02127	1.07e-98	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
GIIPGHNE_02128	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GIIPGHNE_02129	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
GIIPGHNE_02130	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GIIPGHNE_02131	4.63e-135	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
GIIPGHNE_02132	4.19e-265	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
GIIPGHNE_02133	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
GIIPGHNE_02134	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GIIPGHNE_02135	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GIIPGHNE_02136	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GIIPGHNE_02137	2.15e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
GIIPGHNE_02138	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
GIIPGHNE_02139	8.62e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
GIIPGHNE_02140	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
GIIPGHNE_02141	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
GIIPGHNE_02142	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
GIIPGHNE_02143	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
GIIPGHNE_02144	8.95e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GIIPGHNE_02145	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GIIPGHNE_02147	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
GIIPGHNE_02148	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
GIIPGHNE_02149	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GIIPGHNE_02150	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
GIIPGHNE_02151	1.19e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GIIPGHNE_02152	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GIIPGHNE_02153	8.46e-170	-	-	-	-	-	-	-	-
GIIPGHNE_02154	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GIIPGHNE_02155	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GIIPGHNE_02156	2.22e-178	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
GIIPGHNE_02157	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GIIPGHNE_02158	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GIIPGHNE_02159	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
GIIPGHNE_02160	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_02161	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_02162	7.98e-137	-	-	-	-	-	-	-	-
GIIPGHNE_02163	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GIIPGHNE_02164	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GIIPGHNE_02165	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
GIIPGHNE_02166	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
GIIPGHNE_02167	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_02168	4e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GIIPGHNE_02169	2.53e-198	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GIIPGHNE_02170	3.09e-213	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
GIIPGHNE_02171	5.13e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
GIIPGHNE_02172	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GIIPGHNE_02173	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GIIPGHNE_02174	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
GIIPGHNE_02175	2.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GIIPGHNE_02176	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
GIIPGHNE_02177	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GIIPGHNE_02178	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GIIPGHNE_02179	5.44e-159	-	-	-	T	-	-	-	EAL domain
GIIPGHNE_02180	3.14e-187	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
GIIPGHNE_02181	1.21e-73	-	-	-	-	-	-	-	-
GIIPGHNE_02182	7.18e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
GIIPGHNE_02183	2.75e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GIIPGHNE_02184	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GIIPGHNE_02185	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_02186	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_02187	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
GIIPGHNE_02188	1.21e-98	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_02189	5.5e-97	-	-	-	M	-	-	-	LysM domain
GIIPGHNE_02190	1.23e-129	-	-	-	M	-	-	-	Lysin motif
GIIPGHNE_02191	1.64e-137	-	-	-	S	-	-	-	SdpI/YhfL protein family
GIIPGHNE_02192	8.8e-70	nudA	-	-	S	-	-	-	ASCH
GIIPGHNE_02193	4.54e-209	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GIIPGHNE_02194	3.57e-120	-	-	-	-	-	-	-	-
GIIPGHNE_02195	1.92e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
GIIPGHNE_02196	1.02e-280	-	-	-	T	-	-	-	diguanylate cyclase
GIIPGHNE_02197	2.13e-96	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
GIIPGHNE_02198	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
GIIPGHNE_02199	5.78e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
GIIPGHNE_02200	4.33e-95	-	-	-	-	-	-	-	-
GIIPGHNE_02201	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GIIPGHNE_02202	7.62e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
GIIPGHNE_02203	3.57e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
GIIPGHNE_02204	1.37e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
GIIPGHNE_02205	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
GIIPGHNE_02206	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
GIIPGHNE_02207	5.44e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
GIIPGHNE_02208	8.38e-152	-	-	-	GM	-	-	-	NAD(P)H-binding
GIIPGHNE_02209	2.31e-277	-	-	-	-	-	-	-	-
GIIPGHNE_02210	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_02211	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_02212	4.79e-47	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
GIIPGHNE_02213	1.47e-201	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
GIIPGHNE_02214	2.43e-208	yhxD	-	-	IQ	-	-	-	KR domain
GIIPGHNE_02216	3.27e-91	-	-	-	-	-	-	-	-
GIIPGHNE_02217	2.88e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_02218	0.0	-	-	-	E	-	-	-	Amino Acid
GIIPGHNE_02219	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
GIIPGHNE_02220	4.91e-285	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
GIIPGHNE_02221	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
GIIPGHNE_02222	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
GIIPGHNE_02223	1.23e-57	-	-	-	S	-	-	-	Cupredoxin-like domain
GIIPGHNE_02224	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
GIIPGHNE_02225	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
GIIPGHNE_02226	1.23e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GIIPGHNE_02227	1.45e-79	-	-	-	S	-	-	-	CHY zinc finger
GIIPGHNE_02228	1.06e-143	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
GIIPGHNE_02229	6.52e-157	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GIIPGHNE_02230	4.45e-116	metP_2	-	-	U	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_02231	5.67e-187	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GIIPGHNE_02232	6.19e-284	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GIIPGHNE_02233	4.31e-278	-	-	-	-	-	-	-	-
GIIPGHNE_02234	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
GIIPGHNE_02235	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GIIPGHNE_02236	3.93e-59	-	-	-	-	-	-	-	-
GIIPGHNE_02237	5.27e-111	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
GIIPGHNE_02238	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
GIIPGHNE_02239	8.6e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
GIIPGHNE_02240	9e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GIIPGHNE_02241	8.95e-60	-	-	-	-	-	-	-	-
GIIPGHNE_02242	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
GIIPGHNE_02243	1.44e-154	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
GIIPGHNE_02244	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
GIIPGHNE_02245	4.39e-71	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
GIIPGHNE_02246	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
GIIPGHNE_02247	1.96e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
GIIPGHNE_02248	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
GIIPGHNE_02249	2.16e-103	-	-	-	-	-	-	-	-
GIIPGHNE_02250	3.45e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GIIPGHNE_02251	6.07e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
GIIPGHNE_02252	1.77e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GIIPGHNE_02253	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_02254	3.91e-100	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
GIIPGHNE_02255	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GIIPGHNE_02256	1.1e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_02257	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
GIIPGHNE_02258	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GIIPGHNE_02259	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
GIIPGHNE_02260	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GIIPGHNE_02261	0.0	-	-	-	M	-	-	-	domain protein
GIIPGHNE_02262	3.5e-88	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
GIIPGHNE_02263	7.98e-202	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GIIPGHNE_02264	2.27e-130	-	-	-	L	-	-	-	Integrase
GIIPGHNE_02265	0.0	-	-	-	M	-	-	-	domain protein
GIIPGHNE_02266	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GIIPGHNE_02267	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GIIPGHNE_02268	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
GIIPGHNE_02269	9.02e-70	-	-	-	-	-	-	-	-
GIIPGHNE_02270	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
GIIPGHNE_02271	2.67e-39	-	-	-	-	-	-	-	-
GIIPGHNE_02272	1.35e-34	-	-	-	-	-	-	-	-
GIIPGHNE_02273	2.8e-130	-	-	-	K	-	-	-	DNA-templated transcription, initiation
GIIPGHNE_02274	1.1e-167	-	-	-	-	-	-	-	-
GIIPGHNE_02275	5.82e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
GIIPGHNE_02276	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
GIIPGHNE_02277	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
GIIPGHNE_02278	5.64e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
GIIPGHNE_02279	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
GIIPGHNE_02280	6e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
GIIPGHNE_02281	3.25e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
GIIPGHNE_02282	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
GIIPGHNE_02283	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
GIIPGHNE_02284	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GIIPGHNE_02285	1e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
GIIPGHNE_02286	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
GIIPGHNE_02287	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GIIPGHNE_02288	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_02289	1.49e-252	-	-	-	M	-	-	-	MucBP domain
GIIPGHNE_02290	7.84e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_02291	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GIIPGHNE_02292	4.5e-75	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
GIIPGHNE_02293	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
GIIPGHNE_02294	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIIPGHNE_02295	5.1e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GIIPGHNE_02296	9.8e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GIIPGHNE_02297	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GIIPGHNE_02298	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
GIIPGHNE_02299	2.5e-132	-	-	-	L	-	-	-	Integrase
GIIPGHNE_02300	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
GIIPGHNE_02301	5.6e-41	-	-	-	-	-	-	-	-
GIIPGHNE_02302	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
GIIPGHNE_02303	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GIIPGHNE_02304	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GIIPGHNE_02305	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GIIPGHNE_02306	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GIIPGHNE_02307	6.56e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GIIPGHNE_02308	2.36e-290	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GIIPGHNE_02309	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
GIIPGHNE_02310	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GIIPGHNE_02311	1.18e-291	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
GIIPGHNE_02312	2.61e-66	-	-	-	-	ko:K19174	-	ko00000,ko02048	-
GIIPGHNE_02313	6.46e-79	-	-	-	L	ko:K19173	-	ko00000,ko02048	COG0433 Predicted ATPase
GIIPGHNE_02314	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
GIIPGHNE_02315	1.23e-160	is18	-	-	L	-	-	-	Integrase core domain
GIIPGHNE_02318	3.48e-78	yoaZ	-	-	S	-	-	-	intracellular protease amidase
GIIPGHNE_02319	1.05e-26	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_02320	2.37e-148	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
GIIPGHNE_02321	6.11e-09	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
GIIPGHNE_02322	3.18e-81	-	-	-	S	-	-	-	PFAM Metallo-beta-lactamase superfamily
GIIPGHNE_02323	5.02e-52	-	-	-	-	-	-	-	-
GIIPGHNE_02324	4.76e-154	-	-	-	Q	-	-	-	Methyltransferase domain
GIIPGHNE_02325	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GIIPGHNE_02326	9.26e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
GIIPGHNE_02327	2.66e-270	xylR	-	-	GK	-	-	-	ROK family
GIIPGHNE_02328	5.21e-151	-	-	-	-	-	-	-	-
GIIPGHNE_02329	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
GIIPGHNE_02330	8.15e-211	-	-	-	-	-	-	-	-
GIIPGHNE_02331	1.66e-259	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
GIIPGHNE_02332	1.92e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
GIIPGHNE_02333	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
GIIPGHNE_02334	5.61e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
GIIPGHNE_02335	4.15e-31	-	-	-	-	-	-	-	-
GIIPGHNE_02336	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GIIPGHNE_02337	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
GIIPGHNE_02338	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
GIIPGHNE_02339	1.12e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
GIIPGHNE_02340	2.18e-304	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GIIPGHNE_02341	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
GIIPGHNE_02342	1.14e-159	vanR	-	-	K	-	-	-	response regulator
GIIPGHNE_02343	5.64e-158	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
GIIPGHNE_02344	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GIIPGHNE_02345	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GIIPGHNE_02346	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
GIIPGHNE_02347	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GIIPGHNE_02348	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
GIIPGHNE_02349	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GIIPGHNE_02350	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
GIIPGHNE_02351	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GIIPGHNE_02352	6.06e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
GIIPGHNE_02353	3.35e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
GIIPGHNE_02354	5.6e-197	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GIIPGHNE_02355	1.95e-186	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_02356	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_02357	8.42e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
GIIPGHNE_02358	1.11e-169	fliY	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
GIIPGHNE_02359	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_02360	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_02361	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
GIIPGHNE_02362	2.53e-126	-	-	-	KT	-	-	-	response to antibiotic
GIIPGHNE_02363	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
GIIPGHNE_02364	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
GIIPGHNE_02365	2.48e-204	-	-	-	S	-	-	-	Putative adhesin
GIIPGHNE_02366	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GIIPGHNE_02367	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GIIPGHNE_02368	2.6e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
GIIPGHNE_02369	1.45e-260	-	-	-	S	-	-	-	DUF218 domain
GIIPGHNE_02370	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
GIIPGHNE_02371	1.76e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_02372	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GIIPGHNE_02373	6.26e-101	-	-	-	-	-	-	-	-
GIIPGHNE_02374	3.28e-195	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
GIIPGHNE_02375	2.05e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GIIPGHNE_02376	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
GIIPGHNE_02377	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
GIIPGHNE_02378	3.14e-153	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
GIIPGHNE_02379	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GIIPGHNE_02380	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
GIIPGHNE_02381	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GIIPGHNE_02382	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
GIIPGHNE_02383	2.16e-199	-	-	-	GM	-	-	-	NmrA-like family
GIIPGHNE_02384	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GIIPGHNE_02385	5.08e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
GIIPGHNE_02387	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
GIIPGHNE_02388	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
GIIPGHNE_02389	1.78e-139	-	-	-	-	-	-	-	-
GIIPGHNE_02390	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
GIIPGHNE_02391	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
GIIPGHNE_02392	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
GIIPGHNE_02393	7.93e-217	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
GIIPGHNE_02394	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_02395	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
GIIPGHNE_02396	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
GIIPGHNE_02397	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
GIIPGHNE_02398	1.03e-34	-	-	-	-	-	-	-	-
GIIPGHNE_02399	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
GIIPGHNE_02400	6.85e-124	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
GIIPGHNE_02401	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
GIIPGHNE_02402	1.31e-64	-	-	-	-	-	-	-	-
GIIPGHNE_02403	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
GIIPGHNE_02404	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
GIIPGHNE_02405	2.68e-32	-	-	-	-	-	-	-	-
GIIPGHNE_02407	3.46e-208	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_02408	1.37e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
GIIPGHNE_02409	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
GIIPGHNE_02410	2.29e-48	-	-	-	-	-	-	-	-
GIIPGHNE_02411	4.54e-45	-	-	-	-	-	-	-	-
GIIPGHNE_02412	8.05e-278	-	-	-	T	-	-	-	diguanylate cyclase
GIIPGHNE_02413	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
GIIPGHNE_02414	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
GIIPGHNE_02415	1.62e-105	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GIIPGHNE_02416	7.57e-61	-	-	-	-	-	-	-	-
GIIPGHNE_02417	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GIIPGHNE_02418	4.37e-241	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GIIPGHNE_02419	2.84e-208	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
GIIPGHNE_02420	2.82e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
GIIPGHNE_02421	1.43e-310	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
GIIPGHNE_02422	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
GIIPGHNE_02423	9.31e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_02424	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GIIPGHNE_02425	1.38e-180	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_02426	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
GIIPGHNE_02427	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GIIPGHNE_02428	1.49e-309	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
GIIPGHNE_02429	2.21e-122	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_02430	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_02431	3.59e-141	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_02432	6.46e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_02433	5.5e-42	-	-	-	-	-	-	-	-
GIIPGHNE_02434	0.0	-	-	-	L	-	-	-	DNA helicase
GIIPGHNE_02435	3.54e-182	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
GIIPGHNE_02436	8.19e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GIIPGHNE_02437	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
GIIPGHNE_02438	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_02439	9.68e-34	-	-	-	-	-	-	-	-
GIIPGHNE_02440	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
GIIPGHNE_02441	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_02442	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_02443	1.16e-207	-	-	-	GK	-	-	-	ROK family
GIIPGHNE_02444	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GIIPGHNE_02445	2.82e-242	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIIPGHNE_02446	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
GIIPGHNE_02447	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
GIIPGHNE_02448	4.65e-229	-	-	-	-	-	-	-	-
GIIPGHNE_02449	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
GIIPGHNE_02450	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
GIIPGHNE_02451	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
GIIPGHNE_02452	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GIIPGHNE_02453	2.64e-122	-	-	-	P	-	-	-	Cadmium resistance transporter
GIIPGHNE_02454	1e-63	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
GIIPGHNE_02455	3.64e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
GIIPGHNE_02456	5.79e-61	-	-	-	-	-	-	-	-
GIIPGHNE_02457	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
GIIPGHNE_02458	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
GIIPGHNE_02459	1.69e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_02460	1.17e-105	gtcA3	-	-	S	-	-	-	GtrA-like protein
GIIPGHNE_02461	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
GIIPGHNE_02462	1.15e-43	-	-	-	-	-	-	-	-
GIIPGHNE_02464	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
GIIPGHNE_02465	1.96e-196	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
GIIPGHNE_02466	7.65e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
GIIPGHNE_02467	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
GIIPGHNE_02468	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_02469	1.09e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
GIIPGHNE_02470	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
GIIPGHNE_02471	2.1e-136	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_02472	4.54e-241	-	-	-	S	-	-	-	Cell surface protein
GIIPGHNE_02473	1.35e-80	-	-	-	-	-	-	-	-
GIIPGHNE_02474	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_02475	5.12e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GIIPGHNE_02476	2.89e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GIIPGHNE_02477	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GIIPGHNE_02478	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GIIPGHNE_02479	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
GIIPGHNE_02480	2.14e-123	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
GIIPGHNE_02481	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
GIIPGHNE_02482	9.86e-117	-	-	-	-	-	-	-	-
GIIPGHNE_02483	5.81e-99	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
GIIPGHNE_02484	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
GIIPGHNE_02486	3.06e-206	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
GIIPGHNE_02487	1.24e-62	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
GIIPGHNE_02488	2.15e-146	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
GIIPGHNE_02489	2.04e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
GIIPGHNE_02490	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
GIIPGHNE_02491	6.63e-204	yicL	-	-	EG	-	-	-	EamA-like transporter family
GIIPGHNE_02492	3.2e-297	-	-	-	M	-	-	-	Collagen binding domain
GIIPGHNE_02493	0.0	-	-	-	I	-	-	-	acetylesterase activity
GIIPGHNE_02494	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
GIIPGHNE_02495	0.0	cadA	-	-	P	-	-	-	P-type ATPase
GIIPGHNE_02497	2.32e-160	-	-	-	S	-	-	-	YjbR
GIIPGHNE_02498	4.53e-283	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
GIIPGHNE_02499	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GIIPGHNE_02500	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
GIIPGHNE_02501	8.82e-124	-	-	-	V	-	-	-	VanZ like family
GIIPGHNE_02502	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
GIIPGHNE_02503	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
GIIPGHNE_02504	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIIPGHNE_02505	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
GIIPGHNE_02506	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
GIIPGHNE_02507	1.99e-126	-	-	-	FG	-	-	-	HIT domain
GIIPGHNE_02508	1.2e-49	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
GIIPGHNE_02509	4.29e-101	-	-	-	-	-	-	-	-
GIIPGHNE_02510	8.79e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GIIPGHNE_02511	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
GIIPGHNE_02512	3.15e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
GIIPGHNE_02513	4.85e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GIIPGHNE_02515	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
GIIPGHNE_02516	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GIIPGHNE_02517	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
GIIPGHNE_02518	2.02e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
GIIPGHNE_02519	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GIIPGHNE_02520	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GIIPGHNE_02521	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
GIIPGHNE_02522	4.43e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GIIPGHNE_02523	1.82e-183	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GIIPGHNE_02524	1.17e-287	yttB	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_02525	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
GIIPGHNE_02526	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GIIPGHNE_02527	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
GIIPGHNE_02528	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GIIPGHNE_02529	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GIIPGHNE_02530	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
GIIPGHNE_02531	5.8e-46	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
GIIPGHNE_02532	2.3e-27	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
GIIPGHNE_02534	2.35e-243	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GIIPGHNE_02535	5.9e-70	cadC	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
GIIPGHNE_02536	0.0	-	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Cadmium transporter
GIIPGHNE_02537	7.68e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
GIIPGHNE_02538	1.98e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GIIPGHNE_02539	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
GIIPGHNE_02540	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
GIIPGHNE_02541	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
GIIPGHNE_02542	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GIIPGHNE_02543	4.61e-120	yebE	-	-	S	-	-	-	UPF0316 protein
GIIPGHNE_02544	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GIIPGHNE_02545	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
GIIPGHNE_02546	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GIIPGHNE_02547	9.48e-263	camS	-	-	S	-	-	-	sex pheromone
GIIPGHNE_02548	5.98e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GIIPGHNE_02549	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GIIPGHNE_02550	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GIIPGHNE_02551	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
GIIPGHNE_02552	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GIIPGHNE_02553	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_02554	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
GIIPGHNE_02555	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_02556	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_02557	3.25e-195	gntR	-	-	K	-	-	-	rpiR family
GIIPGHNE_02558	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GIIPGHNE_02559	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
GIIPGHNE_02560	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
GIIPGHNE_02561	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
GIIPGHNE_02562	9.36e-317	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
GIIPGHNE_02564	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
GIIPGHNE_02565	1.82e-312	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GIIPGHNE_02566	5.54e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GIIPGHNE_02568	7.62e-97	-	-	-	-	-	-	-	-
GIIPGHNE_02569	2.9e-139	-	-	-	-	-	-	-	-
GIIPGHNE_02570	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
GIIPGHNE_02571	6.92e-281	pbpX	-	-	V	-	-	-	Beta-lactamase
GIIPGHNE_02572	1.12e-265	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GIIPGHNE_02573	7.42e-202	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
GIIPGHNE_02574	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GIIPGHNE_02575	3.82e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
GIIPGHNE_02577	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
GIIPGHNE_02578	2.64e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_02579	1.22e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
GIIPGHNE_02580	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GIIPGHNE_02581	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIIPGHNE_02582	1.35e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GIIPGHNE_02583	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_02584	3.2e-209	-	-	-	GM	-	-	-	NmrA-like family
GIIPGHNE_02585	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GIIPGHNE_02586	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GIIPGHNE_02587	5.03e-192	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
GIIPGHNE_02588	2.61e-83	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_02589	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GIIPGHNE_02590	3.74e-228	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
GIIPGHNE_02591	3.03e-113	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_02592	5.63e-262	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
GIIPGHNE_02593	3.98e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_02594	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GIIPGHNE_02595	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GIIPGHNE_02596	5.3e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
GIIPGHNE_02598	0.0	-	-	-	S	-	-	-	MucBP domain
GIIPGHNE_02599	2.69e-101	-	-	-	S	-	-	-	Protein of unknown function, DUF536
GIIPGHNE_02600	3.8e-224	-	-	-	L	-	-	-	Initiator Replication protein
GIIPGHNE_02601	2.45e-44	-	-	-	-	-	-	-	-
GIIPGHNE_02602	9.97e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
GIIPGHNE_02603	3.36e-90	-	-	-	-	-	-	-	-
GIIPGHNE_02604	5.17e-83	-	-	-	-	-	-	-	-
GIIPGHNE_02605	4.4e-138	-	-	-	L	-	-	-	Integrase
GIIPGHNE_02606	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
GIIPGHNE_02607	9.04e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
GIIPGHNE_02608	4.55e-44	-	-	-	-	-	-	-	-
GIIPGHNE_02609	3.04e-24	-	-	-	-	-	-	-	-
GIIPGHNE_02610	7.72e-129	-	-	-	S	-	-	-	Plasmid replication protein
GIIPGHNE_02613	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
GIIPGHNE_02614	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
GIIPGHNE_02615	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GIIPGHNE_02616	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
GIIPGHNE_02617	3.76e-146	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
GIIPGHNE_02618	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GIIPGHNE_02619	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
GIIPGHNE_02620	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
GIIPGHNE_02621	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GIIPGHNE_02622	5.83e-176	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
GIIPGHNE_02623	6.33e-185	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GIIPGHNE_02624	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
GIIPGHNE_02625	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
GIIPGHNE_02626	1.49e-227	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GIIPGHNE_02627	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GIIPGHNE_02628	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
GIIPGHNE_02629	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
GIIPGHNE_02630	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
GIIPGHNE_02631	4.93e-215	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
GIIPGHNE_02632	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
GIIPGHNE_02633	5.31e-217	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GIIPGHNE_02634	2.54e-194	-	-	-	G	-	-	-	Peptidase_C39 like family
GIIPGHNE_02636	2.93e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GIIPGHNE_02637	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
GIIPGHNE_02638	8.87e-106	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
GIIPGHNE_02639	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
GIIPGHNE_02640	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
GIIPGHNE_02641	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GIIPGHNE_02642	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GIIPGHNE_02643	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GIIPGHNE_02644	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GIIPGHNE_02645	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
GIIPGHNE_02646	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GIIPGHNE_02647	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GIIPGHNE_02648	4.33e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
GIIPGHNE_02649	1.07e-245	ysdE	-	-	P	-	-	-	Citrate transporter
GIIPGHNE_02650	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
GIIPGHNE_02651	1.38e-71	-	-	-	S	-	-	-	Cupin domain
GIIPGHNE_02652	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
GIIPGHNE_02654	3.2e-70	-	-	-	-	-	-	-	-
GIIPGHNE_02655	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GIIPGHNE_02656	1.1e-112	-	-	-	-	-	-	-	-
GIIPGHNE_02657	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
GIIPGHNE_02658	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
GIIPGHNE_02660	2.47e-136	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
GIIPGHNE_02661	2.63e-163	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
GIIPGHNE_02662	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
GIIPGHNE_02663	8.2e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GIIPGHNE_02664	8.42e-166	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
GIIPGHNE_02665	2.23e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
GIIPGHNE_02666	4.92e-285	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GIIPGHNE_02667	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GIIPGHNE_02668	1.14e-81	entB	-	-	Q	-	-	-	Isochorismatase family
GIIPGHNE_02669	4.3e-228	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
GIIPGHNE_02670	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
GIIPGHNE_02671	6.88e-278	-	-	-	E	-	-	-	glutamate:sodium symporter activity
GIIPGHNE_02672	1.13e-272	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
GIIPGHNE_02673	1.89e-252	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
GIIPGHNE_02674	1.09e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
GIIPGHNE_02675	7.31e-146	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GIIPGHNE_02676	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_02677	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GIIPGHNE_02678	4.64e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GIIPGHNE_02679	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GIIPGHNE_02680	1.21e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
GIIPGHNE_02681	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
GIIPGHNE_02682	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GIIPGHNE_02683	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GIIPGHNE_02684	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
GIIPGHNE_02685	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
GIIPGHNE_02686	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GIIPGHNE_02687	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
GIIPGHNE_02688	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
GIIPGHNE_02689	8.32e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
GIIPGHNE_02690	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
GIIPGHNE_02691	3.73e-207	-	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_02692	4.94e-114	ykhA	-	-	I	-	-	-	Thioesterase superfamily
GIIPGHNE_02693	2.66e-247	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GIIPGHNE_02694	4.02e-128	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
GIIPGHNE_02695	1.19e-22	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GIIPGHNE_02697	1.66e-45	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
GIIPGHNE_02698	1.02e-259	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GIIPGHNE_02699	1.15e-159	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
GIIPGHNE_02700	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
GIIPGHNE_02701	4.74e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
GIIPGHNE_02702	4.45e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GIIPGHNE_02703	9.57e-73	-	-	-	S	-	-	-	Conserved hypothetical protein 698
GIIPGHNE_02704	4.73e-132	-	-	-	S	-	-	-	Conserved hypothetical protein 698
GIIPGHNE_02705	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
GIIPGHNE_02706	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
GIIPGHNE_02707	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
GIIPGHNE_02709	1.12e-86	-	-	-	M	-	-	-	LysM domain
GIIPGHNE_02710	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
GIIPGHNE_02711	3.02e-173	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
GIIPGHNE_02712	2.9e-171	sppR	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
GIIPGHNE_02713	5.71e-299	plnB	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GIIPGHNE_02714	2.23e-24	plnA	-	-	-	-	-	-	-
GIIPGHNE_02715	1.22e-36	-	-	-	-	-	-	-	-
GIIPGHNE_02716	1.09e-149	-	-	-	-	-	-	-	-
GIIPGHNE_02718	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GIIPGHNE_02719	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GIIPGHNE_02720	1.39e-190	-	-	-	S	-	-	-	hydrolase
GIIPGHNE_02721	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_02722	1.1e-185	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
GIIPGHNE_02723	7.81e-263	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
GIIPGHNE_02724	9.2e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
GIIPGHNE_02725	5.32e-51	-	-	-	-	-	-	-	-
GIIPGHNE_02726	6.97e-45	-	-	-	-	-	-	-	-
GIIPGHNE_02727	4.24e-163	-	-	-	-	-	-	-	-
GIIPGHNE_02728	2.52e-12	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
GIIPGHNE_02729	1.69e-169	-	-	-	-	-	-	-	-
GIIPGHNE_02730	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
GIIPGHNE_02731	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
GIIPGHNE_02732	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
GIIPGHNE_02733	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GIIPGHNE_02734	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
GIIPGHNE_02735	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GIIPGHNE_02737	2.14e-297	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GIIPGHNE_02738	2.07e-40	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GIIPGHNE_02739	1.19e-280	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GIIPGHNE_02740	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_02741	5.44e-99	-	-	-	-	-	-	-	-
GIIPGHNE_02742	1.35e-241	-	-	-	S	-	-	-	Cell surface protein
GIIPGHNE_02743	8.55e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_02744	7.15e-230	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
GIIPGHNE_02745	3.65e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
GIIPGHNE_02746	7.23e-144	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
GIIPGHNE_02747	1.7e-238	ynjC	-	-	S	-	-	-	Cell surface protein
GIIPGHNE_02748	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_02749	2.44e-82	-	-	-	-	-	-	-	-
GIIPGHNE_02750	3.22e-300	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
GIIPGHNE_02751	4.13e-157	-	-	-	-	-	-	-	-
GIIPGHNE_02752	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GIIPGHNE_02753	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GIIPGHNE_02755	2.56e-42	-	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
GIIPGHNE_02756	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GIIPGHNE_02757	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
GIIPGHNE_02758	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
GIIPGHNE_02759	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
GIIPGHNE_02760	5.04e-313	yycH	-	-	S	-	-	-	YycH protein
GIIPGHNE_02761	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GIIPGHNE_02762	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
GIIPGHNE_02764	1.25e-55	-	-	-	-	-	-	-	-
GIIPGHNE_02765	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
GIIPGHNE_02766	1.43e-79	-	-	-	-	-	-	-	-
GIIPGHNE_02767	1.01e-56	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
GIIPGHNE_02770	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
GIIPGHNE_02771	1.35e-263	-	-	-	S	-	-	-	Phage portal protein
GIIPGHNE_02772	0.000703	-	-	-	-	-	-	-	-
GIIPGHNE_02773	2.27e-308	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
GIIPGHNE_02774	2.16e-80	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
GIIPGHNE_02775	5.44e-109	-	-	-	L	-	-	-	overlaps another CDS with the same product name
GIIPGHNE_02776	7.71e-91	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
GIIPGHNE_02777	5.16e-63	-	-	-	S	-	-	-	Head-tail joining protein
GIIPGHNE_02778	6.01e-33	-	-	-	-	-	-	-	-
GIIPGHNE_02779	1.28e-108	-	-	-	-	-	-	-	-
GIIPGHNE_02780	3.06e-289	-	-	-	S	-	-	-	Virulence-associated protein E
GIIPGHNE_02781	8.33e-185	-	-	-	L	-	-	-	DNA replication protein
GIIPGHNE_02782	9.14e-41	-	-	-	-	-	-	-	-
GIIPGHNE_02783	2.88e-15	-	-	-	-	-	-	-	-
GIIPGHNE_02785	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
GIIPGHNE_02786	9.96e-291	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GIIPGHNE_02787	2.54e-50	-	-	-	-	-	-	-	-
GIIPGHNE_02788	1.26e-42	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
GIIPGHNE_02789	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
GIIPGHNE_02790	3.38e-74	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GIIPGHNE_02791	1.85e-41	-	-	-	-	-	-	-	-
GIIPGHNE_02792	2.29e-307	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
GIIPGHNE_02793	2.65e-90	-	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_02794	3.87e-51	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
GIIPGHNE_02795	3.41e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_02796	2.08e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
GIIPGHNE_02797	3.77e-274	-	-	-	S	-	-	-	Membrane
GIIPGHNE_02801	1.95e-73	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GIIPGHNE_02802	5.12e-112	-	-	-	-	-	-	-	-
GIIPGHNE_02803	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GIIPGHNE_02804	1.77e-56	-	-	-	-	-	-	-	-
GIIPGHNE_02805	1.98e-72	repA	-	-	S	-	-	-	Replication initiator protein A
GIIPGHNE_02806	4.81e-232	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
GIIPGHNE_02807	2.61e-69	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
GIIPGHNE_02808	3.03e-49	-	-	-	K	-	-	-	sequence-specific DNA binding
GIIPGHNE_02809	1.15e-57	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
GIIPGHNE_02810	6.25e-138	-	-	-	L	-	-	-	Integrase
GIIPGHNE_02811	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
GIIPGHNE_02812	3.03e-76	yafQ	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
GIIPGHNE_02813	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
GIIPGHNE_02815	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
GIIPGHNE_02816	3.75e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIIPGHNE_02817	1.3e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GIIPGHNE_02818	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GIIPGHNE_02819	3.53e-123	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GIIPGHNE_02820	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GIIPGHNE_02821	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
GIIPGHNE_02822	2.36e-82	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
GIIPGHNE_02824	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
GIIPGHNE_02825	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GIIPGHNE_02826	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GIIPGHNE_02827	8.29e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GIIPGHNE_02828	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GIIPGHNE_02829	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GIIPGHNE_02830	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
GIIPGHNE_02831	2.22e-61	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	carboxylic ester hydrolase activity
GIIPGHNE_02832	9.47e-78	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GIIPGHNE_02833	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
GIIPGHNE_02834	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
GIIPGHNE_02835	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GIIPGHNE_02836	1.82e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
GIIPGHNE_02837	7.9e-165	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
GIIPGHNE_02838	3.39e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GIIPGHNE_02839	1.79e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GIIPGHNE_02840	3.7e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GIIPGHNE_02841	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GIIPGHNE_02842	1.17e-170	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
GIIPGHNE_02843	7.44e-203	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GIIPGHNE_02844	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
GIIPGHNE_02845	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
GIIPGHNE_02846	4.28e-84	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
GIIPGHNE_02847	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GIIPGHNE_02848	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GIIPGHNE_02849	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
GIIPGHNE_02850	1.37e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
GIIPGHNE_02851	1.97e-190	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
GIIPGHNE_02852	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GIIPGHNE_02853	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
GIIPGHNE_02854	5.69e-239	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GIIPGHNE_02855	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_02856	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
GIIPGHNE_02857	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
GIIPGHNE_02858	3.55e-127	ywjB	-	-	H	-	-	-	RibD C-terminal domain
GIIPGHNE_02859	9.77e-259	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GIIPGHNE_02860	8.64e-153	-	-	-	S	-	-	-	Membrane
GIIPGHNE_02861	8.57e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GIIPGHNE_02862	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
GIIPGHNE_02863	4.89e-70	-	-	-	L	-	-	-	recombinase activity
GIIPGHNE_02864	4.95e-20	-	-	-	-	-	-	-	-
GIIPGHNE_02866	2.17e-23	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GIIPGHNE_02867	0.0	-	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
GIIPGHNE_02868	1.66e-84	-	-	-	L	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
GIIPGHNE_02869	2.42e-281	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
GIIPGHNE_02870	2.64e-56	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
GIIPGHNE_02871	7.2e-21	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIIPGHNE_02872	2.2e-45	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GIIPGHNE_02873	1.22e-28	-	-	-	C	ko:K21739	-	ko00000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
GIIPGHNE_02875	7.89e-92	-	-	-	G	-	-	-	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GIIPGHNE_02876	5.66e-23	-	-	-	T	-	-	-	Universal stress protein family
GIIPGHNE_02877	8.1e-199	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
GIIPGHNE_02878	1.68e-50	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
GIIPGHNE_02879	2.08e-109	-	-	-	-	-	-	-	-
GIIPGHNE_02880	2.29e-154	-	-	-	G	-	-	-	polysaccharide deacetylase
GIIPGHNE_02881	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_02882	8.42e-263	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
GIIPGHNE_02883	3.38e-70	-	-	-	-	-	-	-	-
GIIPGHNE_02884	2.49e-95	-	-	-	-	-	-	-	-
GIIPGHNE_02885	1.82e-67	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
GIIPGHNE_02886	3.03e-85	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
GIIPGHNE_02887	7.22e-238	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GIIPGHNE_02888	5.03e-183	-	-	-	-	-	-	-	-
GIIPGHNE_02889	6.48e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
GIIPGHNE_02890	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
GIIPGHNE_02891	1.9e-175	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
GIIPGHNE_02892	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
GIIPGHNE_02893	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_02894	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
GIIPGHNE_02895	4.45e-38	-	-	-	-	-	-	-	-
GIIPGHNE_02896	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
GIIPGHNE_02897	1.17e-114	-	-	-	M	-	-	-	Parallel beta-helix repeats
GIIPGHNE_02898	8.35e-217	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GIIPGHNE_02899	4.51e-46	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
GIIPGHNE_02900	6.15e-112	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
GIIPGHNE_02901	7.34e-128	cps2G	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
GIIPGHNE_02902	3.06e-58	-	-	-	M	-	-	-	group 2 family protein
GIIPGHNE_02903	3.58e-126	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
GIIPGHNE_02907	1.43e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
GIIPGHNE_02908	1.54e-31	-	-	-	-	-	-	-	-
GIIPGHNE_02909	1.38e-174	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
GIIPGHNE_02910	9.78e-219	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GIIPGHNE_02911	3.61e-303	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
GIIPGHNE_02912	1.92e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GIIPGHNE_02913	1.02e-235	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
GIIPGHNE_02914	1.35e-71	-	-	-	S	-	-	-	DJ-1/PfpI family
GIIPGHNE_02915	6.39e-60	-	-	-	S	-	-	-	DJ-1/PfpI family
GIIPGHNE_02916	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
GIIPGHNE_02917	1.28e-196	-	-	-	EG	-	-	-	EamA-like transporter family
GIIPGHNE_02918	8.07e-164	-	-	-	S	-	-	-	Protein of unknown function
GIIPGHNE_02919	0.0	fusA1	-	-	J	-	-	-	elongation factor G
GIIPGHNE_02920	6.65e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GIIPGHNE_02921	7.61e-217	-	-	-	K	-	-	-	WYL domain
GIIPGHNE_02922	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
GIIPGHNE_02923	1.65e-106	-	-	-	S	-	-	-	ASCH
GIIPGHNE_02924	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
GIIPGHNE_02925	1.62e-173	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GIIPGHNE_02926	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
GIIPGHNE_02927	1.87e-249	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GIIPGHNE_02928	2.22e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
GIIPGHNE_02929	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
GIIPGHNE_02930	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
GIIPGHNE_02931	5.5e-202	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
GIIPGHNE_02932	1.17e-210	-	-	-	S	-	-	-	KR domain
GIIPGHNE_02933	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GIIPGHNE_02934	2.49e-95	-	-	-	C	-	-	-	FMN binding
GIIPGHNE_02935	1.46e-204	-	-	-	K	-	-	-	LysR family
GIIPGHNE_02936	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GIIPGHNE_02937	0.0	-	-	-	C	-	-	-	FMN_bind
GIIPGHNE_02938	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
GIIPGHNE_02939	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
GIIPGHNE_02940	3.86e-156	pnb	-	-	C	-	-	-	nitroreductase
GIIPGHNE_02941	5.38e-153	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
GIIPGHNE_02943	2.35e-75	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	plasmid maintenance
GIIPGHNE_02944	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GIIPGHNE_02945	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
GIIPGHNE_02946	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
GIIPGHNE_02947	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GIIPGHNE_02950	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GIIPGHNE_02951	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
GIIPGHNE_02954	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
GIIPGHNE_02955	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
GIIPGHNE_02956	1.03e-227	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GIIPGHNE_02957	1.04e-142	-	-	-	-	-	-	-	-
GIIPGHNE_02958	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GIIPGHNE_02959	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
GIIPGHNE_02960	1.41e-212	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
GIIPGHNE_02961	5.17e-172	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
GIIPGHNE_02962	4.29e-50	-	-	-	-	-	-	-	-
GIIPGHNE_02964	1.37e-182	-	-	-	S	-	-	-	zinc-ribbon domain
GIIPGHNE_02965	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
GIIPGHNE_02966	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GIIPGHNE_02967	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
GIIPGHNE_02968	2e-209	-	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_02969	1.16e-132	-	-	-	-	-	-	-	-
GIIPGHNE_02970	7.16e-30	-	-	-	-	-	-	-	-
GIIPGHNE_02971	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GIIPGHNE_02972	1.59e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GIIPGHNE_02973	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
GIIPGHNE_02974	1.56e-108	-	-	-	-	-	-	-	-
GIIPGHNE_02975	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
GIIPGHNE_02976	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GIIPGHNE_02977	1.9e-161	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
GIIPGHNE_02978	1.03e-27	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
GIIPGHNE_02979	1.48e-175	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
GIIPGHNE_02980	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GIIPGHNE_02981	2e-52	-	-	-	S	-	-	-	Cytochrome B5
GIIPGHNE_02982	0.0	-	-	-	-	-	-	-	-
GIIPGHNE_02983	2.49e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
GIIPGHNE_02984	1.07e-201	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GIIPGHNE_02985	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
GIIPGHNE_02986	1.76e-298	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
GIIPGHNE_02987	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
GIIPGHNE_02988	1.18e-225	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GIIPGHNE_02989	2.78e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GIIPGHNE_02990	9.91e-267	-	-	-	EGP	-	-	-	Major facilitator Superfamily
GIIPGHNE_02991	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
GIIPGHNE_02992	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
GIIPGHNE_02993	1.1e-188	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GIIPGHNE_02994	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
GIIPGHNE_02995	9.53e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_02996	4.44e-169	-	-	-	M	-	-	-	Phosphotransferase enzyme family
GIIPGHNE_02997	7.2e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GIIPGHNE_02998	2.7e-132	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
GIIPGHNE_02999	1.98e-193	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
GIIPGHNE_03000	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GIIPGHNE_03001	6.49e-143	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
GIIPGHNE_03002	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
GIIPGHNE_03006	1.88e-315	-	-	-	EGP	-	-	-	Major Facilitator
GIIPGHNE_03007	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_03008	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GIIPGHNE_03010	1.22e-247	-	-	-	C	-	-	-	Aldo/keto reductase family
GIIPGHNE_03011	2.64e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
GIIPGHNE_03012	1.35e-282	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
GIIPGHNE_03013	3.73e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
GIIPGHNE_03014	8.47e-36	-	-	-	-	-	-	-	-
GIIPGHNE_03015	1.07e-57	-	-	-	-	-	-	-	-
GIIPGHNE_03016	1.19e-160	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
GIIPGHNE_03017	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
GIIPGHNE_03018	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
GIIPGHNE_03019	5.22e-45	-	-	-	-	-	-	-	-
GIIPGHNE_03020	8.31e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
GIIPGHNE_03021	2.03e-248	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
GIIPGHNE_03022	2.53e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
GIIPGHNE_03023	6.67e-204	-	-	-	K	-	-	-	LysR substrate binding domain
GIIPGHNE_03024	1.49e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
GIIPGHNE_03025	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
GIIPGHNE_03026	2.81e-64	-	-	-	-	-	-	-	-
GIIPGHNE_03027	9.76e-50	-	-	-	-	-	-	-	-
GIIPGHNE_03028	1.08e-112	yvbK	-	-	K	-	-	-	GNAT family
GIIPGHNE_03029	9.82e-111	-	-	-	-	-	-	-	-
GIIPGHNE_03030	2.15e-144	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GIIPGHNE_03031	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GIIPGHNE_03032	9.1e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
GIIPGHNE_03033	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GIIPGHNE_03035	2.36e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_03036	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GIIPGHNE_03037	2.07e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
GIIPGHNE_03038	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
GIIPGHNE_03039	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
GIIPGHNE_03040	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
GIIPGHNE_03041	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
GIIPGHNE_03042	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GIIPGHNE_03043	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_03044	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
GIIPGHNE_03045	1.01e-188	-	-	-	-	-	-	-	-
GIIPGHNE_03046	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
GIIPGHNE_03047	7.9e-269	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GIIPGHNE_03048	1.2e-216	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GIIPGHNE_03049	5.2e-54	-	-	-	-	-	-	-	-
GIIPGHNE_03051	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GIIPGHNE_03052	5.62e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GIIPGHNE_03053	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_03054	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GIIPGHNE_03055	1.22e-108	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GIIPGHNE_03056	4.68e-198	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GIIPGHNE_03057	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GIIPGHNE_03058	4.31e-180	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
GIIPGHNE_03059	7.51e-316	steT	-	-	E	ko:K03294	-	ko00000	amino acid
GIIPGHNE_03060	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
GIIPGHNE_03061	3.61e-190	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
GIIPGHNE_03062	3.08e-93	-	-	-	K	-	-	-	MarR family
GIIPGHNE_03063	1.31e-268	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GIIPGHNE_03064	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GIIPGHNE_03065	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GIIPGHNE_03066	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GIIPGHNE_03067	1.13e-102	rppH3	-	-	F	-	-	-	NUDIX domain
GIIPGHNE_03068	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
GIIPGHNE_03069	1.61e-36	-	-	-	-	-	-	-	-
GIIPGHNE_03070	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
GIIPGHNE_03071	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
GIIPGHNE_03072	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
GIIPGHNE_03073	1.19e-226	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
GIIPGHNE_03074	3.07e-203	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GIIPGHNE_03075	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GIIPGHNE_03076	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GIIPGHNE_03077	1.82e-144	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
GIIPGHNE_03078	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
GIIPGHNE_03079	3.59e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
GIIPGHNE_03080	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
GIIPGHNE_03081	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
GIIPGHNE_03082	1.08e-71	-	-	-	-	-	-	-	-
GIIPGHNE_03083	5.57e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
GIIPGHNE_03084	0.0	-	-	-	L	-	-	-	AAA domain
GIIPGHNE_03085	2.01e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
GIIPGHNE_03086	9.33e-37	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
GIIPGHNE_03087	1.05e-195	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
GIIPGHNE_03088	3.61e-61	-	-	-	S	-	-	-	MORN repeat
GIIPGHNE_03089	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
GIIPGHNE_03090	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
GIIPGHNE_03091	1.95e-116	-	-	-	-	-	-	-	-
GIIPGHNE_03092	5.74e-32	-	-	-	-	-	-	-	-
GIIPGHNE_03093	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GIIPGHNE_03094	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GIIPGHNE_03095	1.36e-190	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
GIIPGHNE_03096	1.22e-210	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
GIIPGHNE_03097	4.46e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
GIIPGHNE_03098	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
GIIPGHNE_03099	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
GIIPGHNE_03100	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
GIIPGHNE_03101	2.48e-24	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
GIIPGHNE_03102	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
GIIPGHNE_03103	1.51e-72	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GIIPGHNE_03104	4.43e-220	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GIIPGHNE_03105	3.34e-37	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GIIPGHNE_03106	1.05e-71	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GIIPGHNE_03107	4.85e-119	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
GIIPGHNE_03108	0.0	-	-	-	M	-	-	-	MucBP domain
GIIPGHNE_03109	1.42e-08	-	-	-	-	-	-	-	-
GIIPGHNE_03110	1.27e-115	-	-	-	S	-	-	-	AAA domain
GIIPGHNE_03111	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
GIIPGHNE_03112	1.09e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
GIIPGHNE_03113	4.59e-219	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_03114	0.0	-	-	-	C	-	-	-	FMN_bind
GIIPGHNE_03116	1.23e-105	-	-	-	K	-	-	-	Transcriptional regulator
GIIPGHNE_03117	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GIIPGHNE_03118	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
GIIPGHNE_03119	2.78e-254	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
GIIPGHNE_03120	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GIIPGHNE_03121	1.88e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GIIPGHNE_03122	9.05e-55	-	-	-	-	-	-	-	-
GIIPGHNE_03123	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
GIIPGHNE_03124	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
GIIPGHNE_03125	1.58e-207	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GIIPGHNE_03126	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
GIIPGHNE_03127	3.96e-177	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
GIIPGHNE_03128	2.64e-242	-	-	-	-	-	-	-	-
GIIPGHNE_03129	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
GIIPGHNE_03130	2.42e-162	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
GIIPGHNE_03131	3.23e-130	-	-	-	K	-	-	-	FR47-like protein
GIIPGHNE_03132	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
GIIPGHNE_03133	3.33e-64	-	-	-	-	-	-	-	-
GIIPGHNE_03134	1.72e-245	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GIIPGHNE_03135	1.61e-19	xylP2	-	-	G	-	-	-	symporter
GIIPGHNE_03136	4.36e-284	xylP2	-	-	G	-	-	-	symporter