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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
BICEFGKB_00001	1.44e-167	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
BICEFGKB_00002	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
BICEFGKB_00003	9.01e-75	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
BICEFGKB_00004	3.15e-175	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
BICEFGKB_00005	3.68e-271	nirJ	-	-	C	ko:K06139,ko:K22227	-	ko00000	radical SAM domain protein
BICEFGKB_00008	5.91e-199	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
BICEFGKB_00009	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BICEFGKB_00011	1.55e-174	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
BICEFGKB_00012	5.99e-118	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
BICEFGKB_00013	7.98e-59	pspE	-	-	P	ko:K03972	-	ko00000	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BICEFGKB_00014	2.91e-99	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
BICEFGKB_00015	4.08e-43	XK27_05470	-	-	E	-	-	-	Methionine synthase
BICEFGKB_00016	1.84e-98	XK27_05470	-	-	E	-	-	-	Methionine synthase
BICEFGKB_00017	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BICEFGKB_00018	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
BICEFGKB_00019	2.93e-157	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BICEFGKB_00020	6.19e-200	-	-	-	S	-	-	-	TraX protein
BICEFGKB_00021	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BICEFGKB_00022	6.69e-202	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
BICEFGKB_00023	7.29e-215	-	-	-	GK	-	-	-	ROK family
BICEFGKB_00024	6.81e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BICEFGKB_00025	1.46e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BICEFGKB_00026	1.29e-165	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
BICEFGKB_00027	6.43e-117	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
BICEFGKB_00028	5.63e-113	niaX	-	-	-	ko:K16788	-	ko00000,ko02000	-
BICEFGKB_00029	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BICEFGKB_00030	9e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BICEFGKB_00031	1.82e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
BICEFGKB_00032	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
BICEFGKB_00033	0.0	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
BICEFGKB_00034	0.0	sthIR	3.1.21.5	-	S	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction
BICEFGKB_00035	2.47e-28	-	-	-	-	-	-	-	-
BICEFGKB_00037	6.46e-139	adhP	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
BICEFGKB_00038	5.42e-80	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
BICEFGKB_00039	2.18e-10	-	-	-	-	-	-	-	-
BICEFGKB_00040	1.72e-83	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BICEFGKB_00041	1.94e-40	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BICEFGKB_00042	3.92e-91	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BICEFGKB_00043	1.58e-202	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
BICEFGKB_00044	4.34e-145	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_00045	2.37e-135	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_00046	5.22e-75	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
BICEFGKB_00047	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BICEFGKB_00048	7.28e-213	cpsY	-	-	K	-	-	-	Transcriptional regulator
BICEFGKB_00049	2.27e-27	-	-	-	L	ko:K07483	-	ko00000	transposase activity
BICEFGKB_00050	2.64e-153	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
BICEFGKB_00051	2.15e-217	yeiH	-	-	S	-	-	-	Membrane
BICEFGKB_00053	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
BICEFGKB_00054	3.47e-74	XK27_10720	-	-	D	-	-	-	peptidase activity
BICEFGKB_00055	1.01e-70	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BICEFGKB_00057	3.81e-128	-	-	-	-	-	-	-	-
BICEFGKB_00058	2.96e-130	-	-	-	L	-	-	-	Phage integrase family
BICEFGKB_00059	4.49e-191	-	-	-	-	-	-	-	-
BICEFGKB_00060	1.9e-72	hsdS	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K07317	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
BICEFGKB_00061	2.89e-121	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
BICEFGKB_00062	8.27e-195	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
BICEFGKB_00063	1.32e-64	-	-	-	L	ko:K07497	-	ko00000	transposition
BICEFGKB_00064	8.09e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_00067	3.02e-23	-	-	-	-	-	-	-	-
BICEFGKB_00068	1.55e-72	WQ51_06355	-	-	S	-	-	-	TM2 domain
BICEFGKB_00069	2.26e-210	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
BICEFGKB_00070	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
BICEFGKB_00071	3.64e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
BICEFGKB_00072	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
BICEFGKB_00073	1.17e-110	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
BICEFGKB_00074	8.94e-63	cof	-	-	Q	-	-	-	phosphatase activity
BICEFGKB_00075	3.26e-48	cof	-	-	Q	-	-	-	phosphatase activity
BICEFGKB_00076	6e-126	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
BICEFGKB_00077	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
BICEFGKB_00078	8.75e-94	napB	-	-	K	-	-	-	transcriptional
BICEFGKB_00079	4.3e-296	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
BICEFGKB_00080	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BICEFGKB_00081	6.15e-195	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BICEFGKB_00082	2.75e-90	yhaI	-	-	L	-	-	-	Membrane
BICEFGKB_00083	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
BICEFGKB_00084	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
BICEFGKB_00085	1.72e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BICEFGKB_00086	8.82e-124	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
BICEFGKB_00087	1.97e-66	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BICEFGKB_00088	8.75e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
BICEFGKB_00089	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
BICEFGKB_00090	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
BICEFGKB_00091	5.18e-27	XK27_11680	-	-	-	-	-	-	-
BICEFGKB_00092	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
BICEFGKB_00093	3.04e-105	XK27_09675	-	-	K	ko:K07105	-	ko00000	-acetyltransferase
BICEFGKB_00094	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BICEFGKB_00095	8.25e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BICEFGKB_00096	3.12e-115	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_00097	1.52e-211	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BICEFGKB_00098	3.88e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
BICEFGKB_00099	6.83e-169	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BICEFGKB_00100	4.09e-121	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
BICEFGKB_00101	3.61e-131	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
BICEFGKB_00104	2.35e-309	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BICEFGKB_00105	4.8e-116	-	-	-	K	-	-	-	transcriptional regulator
BICEFGKB_00106	5.74e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
BICEFGKB_00107	1.89e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
BICEFGKB_00108	1.29e-233	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BICEFGKB_00109	6.43e-127	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
BICEFGKB_00110	2.48e-111	ykuL	-	-	S	-	-	-	CBS domain
BICEFGKB_00111	4.14e-175	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
BICEFGKB_00112	9.6e-156	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BICEFGKB_00113	7.56e-129	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BICEFGKB_00114	3.14e-179	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
BICEFGKB_00115	1.81e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
BICEFGKB_00116	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
BICEFGKB_00117	1.1e-311	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
BICEFGKB_00118	1.34e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BICEFGKB_00119	1.94e-118	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BICEFGKB_00120	1.5e-144	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
BICEFGKB_00121	2.94e-206	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
BICEFGKB_00122	1.13e-44	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
BICEFGKB_00123	2.45e-141	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BICEFGKB_00124	2.53e-67	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BICEFGKB_00125	1.77e-207	-	-	-	L	ko:K07485	-	ko00000	Transposase
BICEFGKB_00126	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BICEFGKB_00127	2.22e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
BICEFGKB_00128	8.87e-306	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BICEFGKB_00129	8.89e-306	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
BICEFGKB_00130	1.94e-05	-	-	-	-	-	-	-	-
BICEFGKB_00131	4.75e-80	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
BICEFGKB_00132	3.77e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
BICEFGKB_00133	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BICEFGKB_00134	4.43e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BICEFGKB_00135	1.06e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BICEFGKB_00136	8.11e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
BICEFGKB_00137	6.38e-259	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BICEFGKB_00138	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BICEFGKB_00139	7.94e-173	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
BICEFGKB_00140	5.34e-270	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
BICEFGKB_00141	5.14e-111	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BICEFGKB_00142	6.08e-154	yveI	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BICEFGKB_00146	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
BICEFGKB_00147	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
BICEFGKB_00148	5.63e-195	XK27_10395	-	-	S	-	-	-	membrane
BICEFGKB_00149	3.34e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
BICEFGKB_00150	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
BICEFGKB_00151	1.06e-260	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BICEFGKB_00152	3.04e-68	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
BICEFGKB_00153	1.24e-298	albE	-	-	S	-	-	-	Peptidase M16
BICEFGKB_00154	4.21e-290	ymfH	-	-	S	-	-	-	Peptidase M16
BICEFGKB_00155	1.2e-182	ymfM	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
BICEFGKB_00156	7.67e-118	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BICEFGKB_00157	7.44e-193	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BICEFGKB_00158	7.14e-193	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BICEFGKB_00159	6.74e-174	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BICEFGKB_00160	4.41e-119	lytE	-	-	M	-	-	-	LysM domain protein
BICEFGKB_00161	3.63e-90	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
BICEFGKB_00162	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
BICEFGKB_00163	1.37e-271	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BICEFGKB_00164	3.87e-97	-	-	-	F	-	-	-	NUDIX domain
BICEFGKB_00165	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BICEFGKB_00166	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
BICEFGKB_00167	3.57e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
BICEFGKB_00168	1.29e-312	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
BICEFGKB_00169	3.05e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
BICEFGKB_00170	1.39e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BICEFGKB_00171	4.05e-11	-	-	-	-	-	-	-	-
BICEFGKB_00172	1.19e-15	XK27_04840	-	-	M	ko:K08987	-	ko00000	Membrane
BICEFGKB_00173	5.43e-122	XK27_06935	-	-	K	-	-	-	transcriptional regulator
BICEFGKB_00174	1.87e-249	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
BICEFGKB_00175	5.78e-147	-	-	-	S	-	-	-	Putative adhesin
BICEFGKB_00176	1.42e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
BICEFGKB_00177	9.72e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
BICEFGKB_00178	1.34e-63	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator, PadR family
BICEFGKB_00179	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BICEFGKB_00180	1.66e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
BICEFGKB_00181	4.47e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BICEFGKB_00182	8.33e-156	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
BICEFGKB_00183	1.4e-46	XK27_09115	-	-	M	-	-	-	LysM domain
BICEFGKB_00184	1.79e-116	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
BICEFGKB_00185	1.59e-176	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
BICEFGKB_00186	1.58e-53	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
BICEFGKB_00187	1.32e-125	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
BICEFGKB_00188	4.49e-284	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
BICEFGKB_00189	1.22e-231	XK27_05220	-	-	S	-	-	-	permease
BICEFGKB_00190	3.52e-120	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
BICEFGKB_00191	1.34e-207	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
BICEFGKB_00192	1.04e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
BICEFGKB_00193	7.29e-230	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BICEFGKB_00194	2.49e-262	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BICEFGKB_00195	2.13e-231	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
BICEFGKB_00196	5.64e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
BICEFGKB_00197	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
BICEFGKB_00198	1.69e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
BICEFGKB_00199	3.98e-59	XK27_00115	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
BICEFGKB_00200	5.66e-189	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
BICEFGKB_00201	1.49e-293	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
BICEFGKB_00202	5.94e-46	-	-	-	F	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
BICEFGKB_00203	1.7e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
BICEFGKB_00204	5.5e-315	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BICEFGKB_00205	2.49e-166	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BICEFGKB_00206	5.43e-180	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_00207	9.79e-194	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
BICEFGKB_00208	2.28e-156	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_00209	1.18e-141	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
BICEFGKB_00210	2.18e-194	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
BICEFGKB_00211	4.09e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
BICEFGKB_00212	2.4e-295	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BICEFGKB_00214	5.18e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
BICEFGKB_00215	6.31e-43	-	5.1.3.2	-	GM	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	ko00000,ko00001,ko00002,ko01000	Psort location CytoplasmicMembrane, score
BICEFGKB_00216	5.75e-267	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BICEFGKB_00217	2.38e-223	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
BICEFGKB_00218	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BICEFGKB_00219	3.2e-116	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
BICEFGKB_00220	2.04e-207	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BICEFGKB_00221	9.42e-28	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
BICEFGKB_00223	5.73e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BICEFGKB_00224	4.32e-279	-	-	-	P	-	-	-	chloride
BICEFGKB_00225	1.27e-55	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
BICEFGKB_00226	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
BICEFGKB_00227	3.48e-98	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
BICEFGKB_00229	3.12e-162	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
BICEFGKB_00230	7.21e-192	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
BICEFGKB_00231	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BICEFGKB_00232	1.81e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_00233	1.71e-184	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BICEFGKB_00234	2.67e-226	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
BICEFGKB_00235	5.6e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF4649)
BICEFGKB_00236	1.29e-14	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
BICEFGKB_00237	8.76e-18	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
BICEFGKB_00238	0.000849	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
BICEFGKB_00239	5.63e-12	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
BICEFGKB_00240	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
BICEFGKB_00241	9.03e-256	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
BICEFGKB_00242	2.28e-178	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
BICEFGKB_00243	9.81e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BICEFGKB_00244	8.21e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
BICEFGKB_00245	3.06e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BICEFGKB_00246	1.59e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
BICEFGKB_00247	3.79e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
BICEFGKB_00248	1.84e-127	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
BICEFGKB_00249	6.93e-79	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BICEFGKB_00250	2.04e-102	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BICEFGKB_00251	3.42e-84	-	-	-	-	-	-	-	-
BICEFGKB_00252	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BICEFGKB_00253	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BICEFGKB_00254	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BICEFGKB_00255	0.0	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BICEFGKB_00256	1.96e-125	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BICEFGKB_00257	2.31e-197	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
BICEFGKB_00258	2.48e-129	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
BICEFGKB_00259	3.67e-181	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BICEFGKB_00260	2.61e-303	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
BICEFGKB_00261	6.2e-98	XK27_03180	-	-	T	-	-	-	universal stress protein
BICEFGKB_00263	6.98e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BICEFGKB_00264	1.17e-303	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
BICEFGKB_00265	1.5e-184	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_00266	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
BICEFGKB_00268	3.01e-125	mraW1	-	-	J	-	-	-	(SAM)-dependent
BICEFGKB_00269	2.93e-230	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
BICEFGKB_00270	7.32e-248	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
BICEFGKB_00271	1.31e-113	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BICEFGKB_00272	1.05e-119	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
BICEFGKB_00273	1.95e-219	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BICEFGKB_00274	1.81e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
BICEFGKB_00275	9.69e-170	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_00276	7.25e-208	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_00277	2.46e-193	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
BICEFGKB_00279	7.44e-257	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BICEFGKB_00280	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
BICEFGKB_00281	3.81e-55	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
BICEFGKB_00282	5.6e-50	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
BICEFGKB_00283	3.8e-111	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BICEFGKB_00284	5.11e-10	hsdS_1	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
BICEFGKB_00285	4.64e-108	-	-	-	L	-	-	-	Plasmid recombination enzyme
BICEFGKB_00286	1.62e-43	-	-	-	L	ko:K04763	-	ko00000,ko03036	DNA integration
BICEFGKB_00287	1.67e-75	-	-	-	L	-	-	-	Phage integrase family
BICEFGKB_00288	1.44e-157	XK27_05540	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
BICEFGKB_00289	1.3e-160	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
BICEFGKB_00290	3.42e-150	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_00291	2.76e-42	-	-	-	-	-	-	-	-
BICEFGKB_00292	3.97e-233	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
BICEFGKB_00293	1.05e-175	cppA	-	-	E	-	-	-	CppA N-terminal
BICEFGKB_00294	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_00295	1.53e-175	-	-	-	HJ	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
BICEFGKB_00296	2.15e-156	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
BICEFGKB_00297	5.37e-31	-	-	-	K	-	-	-	CsbD-like
BICEFGKB_00298	1.06e-106	-	-	-	M	-	-	-	Protein conserved in bacteria
BICEFGKB_00299	1.03e-30	-	-	-	S	-	-	-	Small integral membrane protein
BICEFGKB_00300	1.36e-50	-	-	-	-	-	-	-	-
BICEFGKB_00301	1.07e-40	-	-	-	-	-	-	-	-
BICEFGKB_00302	7.98e-45	ytgB	-	-	S	-	-	-	Membrane
BICEFGKB_00303	1.01e-251	-	-	-	L	ko:K07481	-	ko00000	transposase, IS4 family
BICEFGKB_00304	3.44e-120	-	-	-	P	-	-	-	Major facilitator superfamily
BICEFGKB_00305	1.54e-42	-	-	-	L	ko:K07485	-	ko00000	Transposase
BICEFGKB_00306	1.14e-128	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
BICEFGKB_00307	2.1e-37	-	-	-	-	-	-	-	-
BICEFGKB_00308	8.55e-71	-	-	-	-	-	-	-	-
BICEFGKB_00309	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
BICEFGKB_00310	3.07e-48	-	-	-	-	-	-	-	-
BICEFGKB_00311	1.11e-47	MA20_20425	2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5	-	E	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
BICEFGKB_00312	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BICEFGKB_00313	2.77e-133	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
BICEFGKB_00314	2.69e-231	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BICEFGKB_00315	3.23e-172	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
BICEFGKB_00316	8.83e-128	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
BICEFGKB_00317	5.8e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BICEFGKB_00318	2.49e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
BICEFGKB_00319	4.28e-97	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor, CopY TcrY family
BICEFGKB_00320	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
BICEFGKB_00321	1.58e-41	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
BICEFGKB_00322	9.64e-248	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
BICEFGKB_00323	2.87e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_00324	3.24e-148	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_00325	1.11e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_00326	9.46e-200	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
BICEFGKB_00329	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BICEFGKB_00330	1.34e-154	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
BICEFGKB_00331	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BICEFGKB_00332	1.43e-106	yjbB	-	-	G	-	-	-	Permeases of the major facilitator superfamily
BICEFGKB_00333	1.15e-81	yjbB	-	-	G	-	-	-	Permeases of the major facilitator superfamily
BICEFGKB_00334	5.67e-198	rgg	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
BICEFGKB_00335	3.09e-127	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
BICEFGKB_00336	1.07e-82	yjqA	-	-	S	-	-	-	Bacterial PH domain
BICEFGKB_00337	3.8e-199	corA	-	-	P	-	-	-	CorA-like protein
BICEFGKB_00338	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BICEFGKB_00339	4.12e-56	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
BICEFGKB_00340	2.05e-179	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
BICEFGKB_00341	8.44e-186	nodB3	-	-	G	-	-	-	deacetylase
BICEFGKB_00342	2.5e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
BICEFGKB_00343	2.9e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
BICEFGKB_00344	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
BICEFGKB_00345	5.05e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BICEFGKB_00346	1.33e-108	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
BICEFGKB_00347	5.15e-100	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
BICEFGKB_00348	4.6e-62	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
BICEFGKB_00349	4.52e-87	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_00350	8.73e-30	yecS	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid transport
BICEFGKB_00351	2.38e-05	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BICEFGKB_00352	1e-27	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BICEFGKB_00353	6.06e-124	yfiF3	-	-	K	-	-	-	sequence-specific DNA binding
BICEFGKB_00354	3.21e-29	bglC	-	-	K	-	-	-	Transcriptional regulator
BICEFGKB_00355	5.47e-316	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BICEFGKB_00356	9.61e-305	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
BICEFGKB_00357	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
BICEFGKB_00358	1.71e-306	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
BICEFGKB_00359	7.95e-171	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
BICEFGKB_00360	3.49e-113	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BICEFGKB_00361	3.31e-143	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
BICEFGKB_00362	1.91e-42	M1-755	-	-	P	ko:K09155	-	ko00000	Hemerythrin HHE cation binding domain protein
BICEFGKB_00363	1.43e-99	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
BICEFGKB_00364	4.6e-41	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
BICEFGKB_00365	7.53e-35	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
BICEFGKB_00366	1.46e-42	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
BICEFGKB_00367	2.43e-194	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BICEFGKB_00368	6.55e-221	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
BICEFGKB_00369	2.42e-91	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BICEFGKB_00370	9.86e-59	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
BICEFGKB_00371	6.89e-183	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
BICEFGKB_00372	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
BICEFGKB_00373	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
BICEFGKB_00374	4.63e-201	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
BICEFGKB_00375	7.15e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
BICEFGKB_00376	5.27e-193	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BICEFGKB_00377	1.75e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BICEFGKB_00378	7.71e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
BICEFGKB_00379	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
BICEFGKB_00380	2.19e-248	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
BICEFGKB_00381	1.25e-238	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
BICEFGKB_00385	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
BICEFGKB_00386	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
BICEFGKB_00387	1.29e-62	malR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
BICEFGKB_00389	4.79e-34	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
BICEFGKB_00390	2.02e-156	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BICEFGKB_00391	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
BICEFGKB_00392	7.41e-297	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
BICEFGKB_00393	1.06e-200	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
BICEFGKB_00394	4.39e-42	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00395	4.24e-111	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00396	5.89e-70	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00397	1.42e-252	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00398	2.32e-235	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
BICEFGKB_00399	7.26e-80	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
BICEFGKB_00400	1.39e-15	-	3.5.1.28	-	S	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036	dextransucrase activity
BICEFGKB_00401	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
BICEFGKB_00402	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_00403	3.89e-78	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
BICEFGKB_00404	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
BICEFGKB_00405	0.0	noxE	-	-	P	-	-	-	NADH oxidase
BICEFGKB_00406	6.88e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
BICEFGKB_00407	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BICEFGKB_00408	2.18e-169	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
BICEFGKB_00409	1.13e-68	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 LactoylglutaTHIone lyase and related lyases
BICEFGKB_00410	9.81e-212	ypuA	-	-	S	-	-	-	secreted protein
BICEFGKB_00411	2.38e-79	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
BICEFGKB_00412	6.81e-92	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
BICEFGKB_00414	6.93e-236	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BICEFGKB_00415	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BICEFGKB_00416	2.77e-45	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
BICEFGKB_00417	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BICEFGKB_00418	4.25e-271	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
BICEFGKB_00419	1.4e-280	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
BICEFGKB_00420	3.31e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
BICEFGKB_00421	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BICEFGKB_00422	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
BICEFGKB_00423	2.36e-38	-	6.3.2.2, 6.3.2.4	-	F	ko:K01919,ko:K01921	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502	ko00000,ko00001,ko00002,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
BICEFGKB_00424	1.85e-242	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
BICEFGKB_00425	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
BICEFGKB_00426	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
BICEFGKB_00428	2.49e-168	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
BICEFGKB_00429	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BICEFGKB_00430	1.02e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
BICEFGKB_00431	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
BICEFGKB_00432	1.91e-159	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BICEFGKB_00433	1.16e-214	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
BICEFGKB_00434	1.29e-315	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BICEFGKB_00435	2.02e-92	mesH	-	-	S	-	-	-	GtrA-like protein
BICEFGKB_00436	2.59e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
BICEFGKB_00437	1.15e-189	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BICEFGKB_00438	3.79e-28	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
BICEFGKB_00439	4.34e-129	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
BICEFGKB_00440	8.05e-260	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
BICEFGKB_00441	1.58e-205	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BICEFGKB_00442	9.6e-143	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BICEFGKB_00443	1.91e-263	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BICEFGKB_00446	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_00447	1.66e-106	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BICEFGKB_00448	3.67e-62	yhaI	-	-	L	-	-	-	Membrane
BICEFGKB_00449	8.86e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
BICEFGKB_00450	6.21e-124	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
BICEFGKB_00451	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
BICEFGKB_00452	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
BICEFGKB_00453	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
BICEFGKB_00454	2.74e-101	ureE	-	-	O	ko:K03187	-	ko00000	enzyme active site formation
BICEFGKB_00455	1.83e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BICEFGKB_00456	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BICEFGKB_00457	2.43e-204	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
BICEFGKB_00458	5e-227	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
BICEFGKB_00459	2.37e-176	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
BICEFGKB_00460	4.48e-170	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
BICEFGKB_00461	3.69e-196	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	amino acid transport
BICEFGKB_00462	0.0	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BICEFGKB_00463	0.0	-	-	-	F	-	-	-	NUDIX domain
BICEFGKB_00464	7.28e-268	-	-	-	EGP	-	-	-	Transmembrane secretion effector
BICEFGKB_00465	9.97e-185	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	amino acid transport
BICEFGKB_00466	2.14e-202	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
BICEFGKB_00467	0.0	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
BICEFGKB_00468	1.01e-232	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BICEFGKB_00469	1.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_00470	3.61e-268	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BICEFGKB_00471	1.25e-203	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
BICEFGKB_00472	5.41e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
BICEFGKB_00473	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_00474	5.03e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
BICEFGKB_00475	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BICEFGKB_00476	2.41e-15	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-ascorbate 6-phosphate lactonase
BICEFGKB_00477	2.81e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
BICEFGKB_00478	1.05e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
BICEFGKB_00479	2.13e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
BICEFGKB_00480	2.69e-117	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
BICEFGKB_00481	1.28e-156	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BICEFGKB_00482	0.0	covS	-	-	T	-	-	-	Histidine kinase
BICEFGKB_00483	8.44e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BICEFGKB_00484	1.28e-276	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
BICEFGKB_00485	1.53e-213	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
BICEFGKB_00486	4.84e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
BICEFGKB_00487	8.61e-18	yrdC	-	-	Q	-	-	-	isochorismatase
BICEFGKB_00488	8.53e-37	yrdC	-	-	Q	-	-	-	isochorismatase
BICEFGKB_00489	1.14e-296	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
BICEFGKB_00490	7.6e-70	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
BICEFGKB_00491	3.1e-138	mur1	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	mannosyl-glycoprotein
BICEFGKB_00492	3.41e-192	XK27_04800	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
BICEFGKB_00493	4.96e-116	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
BICEFGKB_00494	1.98e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BICEFGKB_00495	1.64e-68	-	-	-	-	-	-	-	-
BICEFGKB_00496	1.94e-34	-	-	-	-	-	-	-	-
BICEFGKB_00497	8.89e-80	-	-	-	-	-	-	-	-
BICEFGKB_00498	2.73e-78	-	-	-	S	-	-	-	membrane
BICEFGKB_00499	3.53e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
BICEFGKB_00500	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
BICEFGKB_00501	1.42e-52	ynzC	-	-	S	-	-	-	UPF0291 protein
BICEFGKB_00502	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
BICEFGKB_00504	4.1e-30	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_00505	3.51e-148	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_00506	2.29e-64	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_00507	2.13e-180	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BICEFGKB_00512	4.06e-214	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
BICEFGKB_00513	4.01e-100	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BICEFGKB_00514	1.71e-208	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
BICEFGKB_00515	2.72e-114	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BICEFGKB_00516	8.22e-288	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
BICEFGKB_00517	8.28e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
BICEFGKB_00518	1.31e-268	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
BICEFGKB_00519	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
BICEFGKB_00520	1.51e-159	-	-	-	S	-	-	-	Putative SAM-dependent methyltransferase
BICEFGKB_00521	6.64e-244	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BICEFGKB_00522	1.08e-155	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BICEFGKB_00523	1.32e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
BICEFGKB_00524	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
BICEFGKB_00525	8.55e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4391)
BICEFGKB_00527	0.0	XK27_03440	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	restriction endonuclease
BICEFGKB_00528	1.7e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BICEFGKB_00529	7.29e-70	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BICEFGKB_00530	3.36e-81	-	-	-	L	ko:K07485	-	ko00000	Transposase
BICEFGKB_00531	1.33e-125	-	-	-	L	ko:K07485	-	ko00000	Transposase
BICEFGKB_00532	1.25e-23	-	-	-	L	-	-	-	Integrase core domain
BICEFGKB_00533	1.62e-152	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_00534	1.21e-225	hrtB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
BICEFGKB_00537	1.16e-127	-	-	-	S	-	-	-	MucBP domain
BICEFGKB_00538	3.02e-59	-	-	-	M	-	-	-	YSIRK type signal peptide
BICEFGKB_00539	0.0	-	-	-	M	-	-	-	the current gene model (or a revised gene model) may contain a
BICEFGKB_00541	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_00542	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_00543	4.12e-253	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BICEFGKB_00544	2.47e-156	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BICEFGKB_00545	8.65e-293	hk02	-	-	T	-	-	-	signal transduction protein with a C-terminal ATPase domain
BICEFGKB_00546	4.85e-169	rr02	-	-	KT	-	-	-	response regulator
BICEFGKB_00547	7.84e-105	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
BICEFGKB_00548	1.73e-135	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
BICEFGKB_00549	8.21e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
BICEFGKB_00550	1.79e-157	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
BICEFGKB_00551	9.26e-249	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
BICEFGKB_00552	3.25e-40	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
BICEFGKB_00554	8.08e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
BICEFGKB_00555	7.29e-146	-	-	-	S	-	-	-	VIT family
BICEFGKB_00556	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
BICEFGKB_00557	8.7e-279	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
BICEFGKB_00558	1.29e-24	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	alanine dehydrogenase activity
BICEFGKB_00559	4.31e-57	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
BICEFGKB_00560	1.69e-314	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BICEFGKB_00561	1.33e-135	-	-	-	J	ko:K09962	-	ko00000	protein conserved in bacteria
BICEFGKB_00562	4.73e-188	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
BICEFGKB_00563	8.91e-220	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
BICEFGKB_00564	3.24e-226	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
BICEFGKB_00565	4.16e-235	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BICEFGKB_00566	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BICEFGKB_00567	8.64e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
BICEFGKB_00568	1.47e-41	-	-	-	-	-	-	-	-
BICEFGKB_00569	7.33e-152	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BICEFGKB_00571	3.42e-35	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
BICEFGKB_00572	3.8e-58	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
BICEFGKB_00573	9.13e-14	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
BICEFGKB_00574	8.17e-242	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
BICEFGKB_00575	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
BICEFGKB_00576	3.19e-66	-	-	-	-	-	-	-	-
BICEFGKB_00577	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BICEFGKB_00578	3.22e-217	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
BICEFGKB_00579	6.47e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
BICEFGKB_00580	9.03e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
BICEFGKB_00581	1.49e-153	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
BICEFGKB_00582	5.64e-294	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
BICEFGKB_00583	4.45e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
BICEFGKB_00584	2.98e-213	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BICEFGKB_00585	2.98e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BICEFGKB_00586	2.97e-30	-	-	-	-	-	-	-	-
BICEFGKB_00587	4.22e-286	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BICEFGKB_00588	6.75e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
BICEFGKB_00589	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
BICEFGKB_00590	2.66e-228	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
BICEFGKB_00591	5.22e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
BICEFGKB_00592	2.2e-20	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
BICEFGKB_00593	4.27e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BICEFGKB_00594	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BICEFGKB_00595	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BICEFGKB_00596	8.31e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
BICEFGKB_00597	1.4e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
BICEFGKB_00600	7.94e-266	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
BICEFGKB_00603	6.33e-132	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
BICEFGKB_00604	2.5e-90	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
BICEFGKB_00605	5.43e-295	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
BICEFGKB_00606	2.22e-65	-	-	-	S	-	-	-	oxidoreductase
BICEFGKB_00607	4.09e-69	-	-	-	S	-	-	-	oxidoreductase
BICEFGKB_00608	7.49e-64	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
BICEFGKB_00609	3.73e-109	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
BICEFGKB_00610	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
BICEFGKB_00611	1.1e-231	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BICEFGKB_00612	1.15e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
BICEFGKB_00613	8.9e-149	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BICEFGKB_00614	4.45e-169	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_00615	2.47e-101	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
BICEFGKB_00616	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
BICEFGKB_00617	9.87e-12	-	-	-	-	-	-	-	-
BICEFGKB_00618	1.61e-44	yugF	-	-	I	-	-	-	carboxylic ester hydrolase activity
BICEFGKB_00619	4.53e-30	-	-	-	I	-	-	-	Alpha/beta hydrolase family
BICEFGKB_00620	2.08e-203	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BICEFGKB_00621	2.91e-191	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BICEFGKB_00622	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
BICEFGKB_00623	2.63e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BICEFGKB_00624	3.45e-08	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
BICEFGKB_00625	1.56e-98	licT	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
BICEFGKB_00626	8.88e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BICEFGKB_00627	9.96e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
BICEFGKB_00628	1.16e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BICEFGKB_00629	1.16e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BICEFGKB_00630	2.68e-137	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BICEFGKB_00631	1.4e-279	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
BICEFGKB_00632	1.5e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
BICEFGKB_00633	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BICEFGKB_00634	5.69e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BICEFGKB_00635	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BICEFGKB_00636	1.08e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
BICEFGKB_00637	8.17e-267	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
BICEFGKB_00638	1.1e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
BICEFGKB_00639	8.52e-34	XK27_07735	-	-	S	-	-	-	YjbR
BICEFGKB_00640	1.17e-141	XK27_07735	-	-	S	-	-	-	YjbR
BICEFGKB_00641	2.96e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
BICEFGKB_00642	6.96e-100	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
BICEFGKB_00643	4.14e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BICEFGKB_00644	1.83e-33	WQ51_00785	-	-	-	-	-	-	-
BICEFGKB_00645	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
BICEFGKB_00646	1.45e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
BICEFGKB_00647	8.04e-158	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BICEFGKB_00648	5.74e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BICEFGKB_00649	1.24e-258	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BICEFGKB_00650	1.29e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BICEFGKB_00651	7.84e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
BICEFGKB_00652	1.48e-71	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
BICEFGKB_00653	8.96e-223	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
BICEFGKB_00654	6.18e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
BICEFGKB_00655	2.28e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BICEFGKB_00656	3.43e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
BICEFGKB_00657	0.0	msrR	-	-	K	-	-	-	Transcriptional regulator
BICEFGKB_00658	4.07e-199	ydiA	-	-	P	ko:K03304,ko:K11041	ko05150,map05150	ko00000,ko00001,ko02000,ko02042	C4-dicarboxylate transporter malic acid transport protein
BICEFGKB_00659	1.56e-256	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
BICEFGKB_00660	5.21e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
BICEFGKB_00661	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BICEFGKB_00662	1.61e-29	-	-	-	-	-	-	-	-
BICEFGKB_00663	6.84e-187	repA	-	-	S	-	-	-	Replication initiator protein A (RepA) N-terminus
BICEFGKB_00664	0.0	hpaIIM	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
BICEFGKB_00665	1.97e-97	XK27_00590	-	-	-	-	-	-	-
BICEFGKB_00666	2.06e-85	XK27_00585	-	-	P	-	-	-	arsenate reductase (glutaredoxin) activity
BICEFGKB_00667	9.04e-50	XK27_00580	-	-	-	-	-	-	-
BICEFGKB_00668	8.62e-115	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
BICEFGKB_00669	1.06e-102	XK27_00570	-	-	-	-	-	-	-
BICEFGKB_00670	0.0	XK27_00565	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
BICEFGKB_00671	4.24e-45	XK27_00560	-	-	-	-	-	-	-
BICEFGKB_00672	1.39e-176	-	-	-	-	-	-	-	-
BICEFGKB_00673	7.46e-81	XK27_00550	-	-	S	-	-	-	PrgI family protein
BICEFGKB_00674	0.0	XK27_00545	-	-	U	-	-	-	'COG3451 Type IV secretory pathway, VirB4 components'
BICEFGKB_00675	0.0	XK27_00530	-	-	M	-	-	-	CHAP domain protein
BICEFGKB_00676	5.34e-61	-	-	-	V	-	-	-	Abi-like protein
BICEFGKB_00677	1.3e-120	-	-	-	V	-	-	-	Abi-like protein
BICEFGKB_00678	0.0	XK27_00515	-	-	D	-	-	-	Glucan-binding protein C
BICEFGKB_00679	3.39e-21	XK27_00510	-	-	-	-	-	-	-
BICEFGKB_00680	9.63e-118	XK27_00505	-	-	-	-	-	-	-
BICEFGKB_00681	0.0	XK27_00500	-	-	L	-	-	-	SNF2 family N-terminal domain
BICEFGKB_00682	4.2e-56	-	-	-	-	-	-	-	-
BICEFGKB_00683	7.1e-49	-	-	-	-	-	-	-	-
BICEFGKB_00684	1.73e-132	XK27_10865	-	-	-	-	-	-	-
BICEFGKB_00685	1.24e-239	-	-	-	L	-	-	-	Toprim-like
BICEFGKB_00686	1.67e-33	XK27_10875	-	-	-	-	-	-	-
BICEFGKB_00687	4.12e-77	XK27_10880	-	-	-	-	-	-	-
BICEFGKB_00688	1.91e-41	-	-	-	-	-	-	-	-
BICEFGKB_00689	4.8e-108	-	-	-	K	ko:K18830	-	ko00000,ko02048,ko03000	Cro/C1-type HTH DNA-binding domain
BICEFGKB_00690	2.16e-167	-	2.7.1.176	-	O	ko:K16214	-	ko00000,ko01000,ko02048	Zeta toxin
BICEFGKB_00691	0.0	-	-	-	L	ko:K07459	-	ko00000	ATP-dependent endonuclease of the OLD family
BICEFGKB_00692	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
BICEFGKB_00693	5.06e-281	-	-	-	K	-	-	-	Putative DNA-binding domain
BICEFGKB_00694	1.89e-75	-	-	-	-	-	-	-	-
BICEFGKB_00695	3.24e-77	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
BICEFGKB_00696	0.0	-	-	-	U	-	-	-	relaxase
BICEFGKB_00697	0.0	scnK	-	-	T	-	-	-	Histidine kinase
BICEFGKB_00698	1.23e-160	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BICEFGKB_00699	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_00704	9.56e-180	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
BICEFGKB_00705	1.34e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BICEFGKB_00706	5.6e-184	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
BICEFGKB_00707	4.76e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BICEFGKB_00708	1.07e-35	-	-	-	-	-	-	-	-
BICEFGKB_00709	4.3e-278	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
BICEFGKB_00710	1.69e-184	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
BICEFGKB_00711	7.72e-231	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BICEFGKB_00712	1.93e-46	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BICEFGKB_00713	4.31e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
BICEFGKB_00714	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BICEFGKB_00715	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BICEFGKB_00716	1.07e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
BICEFGKB_00717	3.96e-131	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BICEFGKB_00718	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
BICEFGKB_00719	5.35e-74	-	-	-	L	ko:K07483	-	ko00000	transposase activity
BICEFGKB_00720	1.25e-68	-	-	-	L	ko:K07497	-	ko00000	transposition
BICEFGKB_00721	3.23e-40	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_00722	1.71e-204	-	-	-	S	-	-	-	CHAP domain
BICEFGKB_00723	4.06e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
BICEFGKB_00724	2.66e-99	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BICEFGKB_00725	3.43e-260	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BICEFGKB_00726	7.34e-59	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
BICEFGKB_00727	3.19e-111	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
BICEFGKB_00728	4.43e-46	-	-	-	-	-	-	-	-
BICEFGKB_00729	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BICEFGKB_00730	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BICEFGKB_00731	1.36e-90	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
BICEFGKB_00732	5.42e-75	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
BICEFGKB_00733	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BICEFGKB_00734	7.24e-102	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
BICEFGKB_00735	2.55e-90	-	-	-	K	-	-	-	LytTr DNA-binding domain
BICEFGKB_00737	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BICEFGKB_00739	4.38e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BICEFGKB_00740	2.69e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
BICEFGKB_00741	8.37e-296	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
BICEFGKB_00742	7.2e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BICEFGKB_00743	1.27e-86	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
BICEFGKB_00744	1.8e-117	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BICEFGKB_00745	3.41e-157	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
BICEFGKB_00746	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BICEFGKB_00747	1.91e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
BICEFGKB_00748	2.63e-214	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
BICEFGKB_00749	2.61e-55	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
BICEFGKB_00750	7.94e-52	XK27_04065	-	-	S	ko:K04767	-	ko00000	CBS domain
BICEFGKB_00751	5.36e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
BICEFGKB_00752	3.96e-177	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
BICEFGKB_00753	1.56e-182	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BICEFGKB_00754	8.19e-190	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BICEFGKB_00755	1.87e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
BICEFGKB_00756	4.33e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
BICEFGKB_00757	2.74e-96	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
BICEFGKB_00758	1.53e-134	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BICEFGKB_00759	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BICEFGKB_00760	4.28e-13	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
BICEFGKB_00761	1.27e-282	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
BICEFGKB_00762	1.19e-256	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
BICEFGKB_00763	1.37e-109	pacL	-	-	P	-	-	-	cation transport ATPase
BICEFGKB_00764	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
BICEFGKB_00765	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BICEFGKB_00766	1.16e-286	femA	2.3.2.17	-	V	ko:K11694	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
BICEFGKB_00768	1.81e-94	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
BICEFGKB_00769	8.07e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BICEFGKB_00770	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BICEFGKB_00771	2.19e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
BICEFGKB_00772	2.72e-63	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
BICEFGKB_00773	2.28e-270	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
BICEFGKB_00774	3.06e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
BICEFGKB_00775	3.4e-276	brpA	-	-	K	-	-	-	Transcriptional
BICEFGKB_00776	6.67e-120	-	-	-	M	-	-	-	Acetyltransferase GNAT Family
BICEFGKB_00777	1.54e-101	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
BICEFGKB_00778	1.13e-307	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
BICEFGKB_00779	2.82e-194	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
BICEFGKB_00780	8.74e-180	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
BICEFGKB_00781	1.14e-230	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_00782	8.44e-162	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
BICEFGKB_00783	8.21e-215	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
BICEFGKB_00784	1.52e-81	manO	-	-	S	-	-	-	protein conserved in bacteria
BICEFGKB_00785	2.31e-306	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BICEFGKB_00789	3.83e-165	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BICEFGKB_00790	1.18e-73	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BICEFGKB_00791	8.01e-295	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BICEFGKB_00792	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
BICEFGKB_00793	1.29e-183	-	-	-	S	-	-	-	SseB protein N-terminal domain
BICEFGKB_00794	7.75e-145	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
BICEFGKB_00795	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
BICEFGKB_00796	4.95e-89	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BICEFGKB_00799	8.3e-171	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BICEFGKB_00800	5.73e-120	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
BICEFGKB_00801	6.39e-199	yitS	-	-	S	-	-	-	DegV family
BICEFGKB_00802	5.6e-28	-	-	-	K	-	-	-	helix-turn-helix
BICEFGKB_00803	5.46e-232	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BICEFGKB_00804	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BICEFGKB_00805	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
BICEFGKB_00806	4.55e-268	-	-	-	L	-	-	-	Phage integrase family
BICEFGKB_00807	4.91e-45	-	-	-	S	-	-	-	Helix-turn-helix domain
BICEFGKB_00808	2.69e-125	-	-	-	S	-	-	-	Plasmid replication protein
BICEFGKB_00809	7.61e-86	-	-	-	-	-	-	-	-
BICEFGKB_00810	2.39e-253	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
BICEFGKB_00811	2.88e-63	-	-	-	-	-	-	-	-
BICEFGKB_00813	5.79e-227	-	-	-	P	-	-	-	Major Facilitator Superfamily
BICEFGKB_00814	1.49e-96	-	-	-	C	-	-	-	nadph quinone reductase
BICEFGKB_00815	8.03e-50	-	-	-	K	-	-	-	Transcriptional regulator
BICEFGKB_00816	2.49e-87	-	-	-	S	ko:K07025	-	ko00000	phosphonoacetaldehyde hydrolase activity
BICEFGKB_00817	3.91e-37	pcaC	3.1.1.24, 4.1.1.44	-	S	ko:K01055,ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	peroxiredoxin activity
BICEFGKB_00818	1.38e-11	-	-	-	G	-	-	-	phosphoglycerate mutase
BICEFGKB_00821	1.39e-164	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
BICEFGKB_00822	6.45e-284	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
BICEFGKB_00823	3.56e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
BICEFGKB_00824	1.95e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
BICEFGKB_00825	6.4e-173	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase
BICEFGKB_00826	7.71e-185	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
BICEFGKB_00827	7.28e-132	acmA	3.2.1.17	-	NU	ko:K01185,ko:K02395	-	ko00000,ko01000,ko02035	amidase activity
BICEFGKB_00828	2.19e-250	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BICEFGKB_00829	2.58e-101	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BICEFGKB_00830	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
BICEFGKB_00831	5.41e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BICEFGKB_00832	7.15e-177	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BICEFGKB_00833	3.02e-176	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
BICEFGKB_00834	9.65e-96	hmpT	-	-	S	-	-	-	cog cog4720
BICEFGKB_00835	4.64e-111	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BICEFGKB_00836	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
BICEFGKB_00837	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
BICEFGKB_00838	1.13e-37	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
BICEFGKB_00839	2.76e-51	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
BICEFGKB_00840	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
BICEFGKB_00841	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
BICEFGKB_00842	8.22e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BICEFGKB_00843	1e-268	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
BICEFGKB_00844	1.8e-06	-	-	-	-	-	-	-	-
BICEFGKB_00845	2.98e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
BICEFGKB_00846	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BICEFGKB_00847	0.0	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
BICEFGKB_00848	1.85e-211	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BICEFGKB_00849	5.33e-163	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
BICEFGKB_00850	8.72e-111	-	-	-	L	ko:K07485	-	ko00000	Transposase
BICEFGKB_00851	1.89e-312	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
BICEFGKB_00852	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BICEFGKB_00853	9.33e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
BICEFGKB_00854	1.2e-204	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BICEFGKB_00855	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
BICEFGKB_00856	3.4e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
BICEFGKB_00857	5.95e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
BICEFGKB_00858	1.83e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
BICEFGKB_00859	8.26e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
BICEFGKB_00860	6.7e-211	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
BICEFGKB_00861	2.27e-221	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
BICEFGKB_00862	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BICEFGKB_00863	1.88e-224	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BICEFGKB_00864	2.67e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
BICEFGKB_00865	1.01e-179	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
BICEFGKB_00866	8.42e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
BICEFGKB_00867	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
BICEFGKB_00868	3.09e-244	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
BICEFGKB_00869	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BICEFGKB_00870	3.96e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
BICEFGKB_00871	9.83e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
BICEFGKB_00872	2.13e-139	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
BICEFGKB_00873	1.1e-136	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
BICEFGKB_00875	0.0	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
BICEFGKB_00876	3.43e-32	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BICEFGKB_00877	2.21e-61	-	-	-	MU	ko:K06236	ko04151,ko04510,ko04512,ko04611,ko04926,ko04933,ko04974,ko05146,ko05165,map04151,map04510,map04512,map04611,map04926,map04933,map04974,map05146,map05165	ko00000,ko00001,ko00536,ko04516	cell adhesion
BICEFGKB_00878	6.51e-82	-	-	-	-	-	-	-	-
BICEFGKB_00879	1.09e-208	-	-	-	-	-	-	-	-
BICEFGKB_00880	6.87e-190	-	-	-	-	-	-	-	-
BICEFGKB_00881	2.99e-219	-	-	-	-	-	-	-	-
BICEFGKB_00882	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
BICEFGKB_00883	5.81e-86	-	-	-	-	-	-	-	-
BICEFGKB_00884	1.26e-113	-	-	-	-	-	-	-	-
BICEFGKB_00885	1.94e-269	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
BICEFGKB_00886	2.86e-303	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
BICEFGKB_00887	0.0	traE	-	-	U	-	-	-	AAA-like domain
BICEFGKB_00888	2.15e-145	-	-	-	-	-	-	-	-
BICEFGKB_00889	2.23e-80	-	-	-	-	-	-	-	-
BICEFGKB_00890	6.09e-70	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
BICEFGKB_00891	0.0	-	-	-	L	-	-	-	MobA/MobL family
BICEFGKB_00892	3.3e-44	-	-	-	-	-	-	-	-
BICEFGKB_00893	2.66e-48	-	-	-	-	-	-	-	-
BICEFGKB_00894	6.06e-36	-	-	-	-	-	-	-	-
BICEFGKB_00895	1.53e-112	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
BICEFGKB_00896	6.22e-72	-	-	-	-	-	-	-	-
BICEFGKB_00897	3.67e-194	-	-	-	S	-	-	-	Zeta toxin
BICEFGKB_00898	8.94e-56	-	-	-	S	-	-	-	Bacterial epsilon antitoxin
BICEFGKB_00899	3.8e-43	-	-	-	S	-	-	-	Omega Transcriptional Repressor
BICEFGKB_00900	1.64e-207	-	-	-	D	-	-	-	AAA domain
BICEFGKB_00901	3.61e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
BICEFGKB_00902	1.23e-160	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_00903	2.43e-83	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
BICEFGKB_00904	1.63e-190	-	-	-	S	-	-	-	overlaps another CDS with the same product name
BICEFGKB_00905	5.25e-193	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
BICEFGKB_00906	1.05e-307	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BICEFGKB_00907	8.75e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
BICEFGKB_00908	6.53e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
BICEFGKB_00909	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BICEFGKB_00910	6.31e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BICEFGKB_00911	6.36e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BICEFGKB_00912	2.48e-166	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
BICEFGKB_00913	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
BICEFGKB_00914	6.28e-154	yvqF	-	-	KT	ko:K11622	ko02020,map02020	ko00000,ko00001	membrane
BICEFGKB_00915	1.31e-223	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BICEFGKB_00916	8.07e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BICEFGKB_00919	4.53e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BICEFGKB_00920	5.68e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
BICEFGKB_00921	4.53e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
BICEFGKB_00922	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
BICEFGKB_00923	3.85e-142	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00924	2.12e-68	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00925	1.62e-14	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00926	9.22e-100	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BICEFGKB_00927	1.55e-29	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BICEFGKB_00928	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
BICEFGKB_00929	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
BICEFGKB_00930	1.49e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
BICEFGKB_00931	2.87e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
BICEFGKB_00932	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
BICEFGKB_00933	1.57e-280	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BICEFGKB_00934	2.71e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
BICEFGKB_00935	3.43e-13	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_00936	3.26e-32	-	-	-	L	ko:K07497	-	ko00000	transposition
BICEFGKB_00937	1.04e-316	zmpB	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	M26 IgA1-specific Metallo-endopeptidase C-terminal region
BICEFGKB_00938	3.69e-125	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
BICEFGKB_00939	2.03e-52	-	-	-	V	ko:K18996,ko:K19171	-	ko00000,ko02048,ko03032	(ABC) transporter
BICEFGKB_00940	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
BICEFGKB_00942	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
BICEFGKB_00943	2.94e-67	-	-	-	K	-	-	-	Acetyltransferase GNAT Family
BICEFGKB_00944	5.33e-167	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
BICEFGKB_00945	1.51e-54	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
BICEFGKB_00946	1.72e-198	-	-	-	C	ko:K06871	-	ko00000	Arylsulfatase regulator (Fe-S oxidoreductase)
BICEFGKB_00950	2.17e-28	-	-	-	L	-	-	-	Transposase
BICEFGKB_00951	2.64e-67	-	-	-	L	-	-	-	Transposase
BICEFGKB_00952	1.67e-173	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
BICEFGKB_00953	1.98e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
BICEFGKB_00954	1.43e-221	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
BICEFGKB_00955	1.86e-135	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
BICEFGKB_00956	6.28e-43	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
BICEFGKB_00957	2.16e-32	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
BICEFGKB_00958	4.64e-72	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
BICEFGKB_00959	1.89e-57	pdp	2.4.2.2, 2.4.2.4	-	F	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	ko00000,ko00001,ko01000	phosphorylase activity
BICEFGKB_00960	2.11e-50	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BICEFGKB_00961	3.68e-62	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
BICEFGKB_00962	9.53e-243	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
BICEFGKB_00963	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BICEFGKB_00964	1.59e-245	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BICEFGKB_00965	2.35e-217	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BICEFGKB_00966	5.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
BICEFGKB_00967	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
BICEFGKB_00968	1.32e-106	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
BICEFGKB_00969	1.83e-277	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
BICEFGKB_00970	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
BICEFGKB_00972	1.21e-253	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
BICEFGKB_00973	1.84e-83	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
BICEFGKB_00974	4.34e-158	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BICEFGKB_00975	1.17e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
BICEFGKB_00976	7.17e-172	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
BICEFGKB_00977	2.72e-122	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
BICEFGKB_00979	2.18e-32	yegS	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	lipid kinase activity
BICEFGKB_00982	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
BICEFGKB_00983	4.33e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
BICEFGKB_00984	2.66e-44	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
BICEFGKB_00985	4.02e-80	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
BICEFGKB_00986	6.96e-65	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
BICEFGKB_00987	6.78e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
BICEFGKB_00989	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BICEFGKB_00990	1.53e-215	XK27_01785	-	-	S	-	-	-	cog cog1284
BICEFGKB_00991	2.8e-188	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
BICEFGKB_00992	2.18e-150	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BICEFGKB_00993	5.35e-118	-	-	-	K	-	-	-	acetyltransferase
BICEFGKB_00994	7.68e-20	-	-	-	-	-	-	-	-
BICEFGKB_00995	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
BICEFGKB_00996	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
BICEFGKB_00997	2.7e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
BICEFGKB_00998	2.06e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BICEFGKB_00999	4.83e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
BICEFGKB_01000	4.09e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
BICEFGKB_01001	1.52e-302	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
BICEFGKB_01003	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
BICEFGKB_01004	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
BICEFGKB_01005	7.46e-200	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
BICEFGKB_01007	6.98e-112	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01008	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01009	6.59e-277	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
BICEFGKB_01010	7.48e-183	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
BICEFGKB_01011	6.89e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BICEFGKB_01012	1.15e-156	-	-	-	S	-	-	-	tigr01906
BICEFGKB_01013	9.8e-181	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
BICEFGKB_01014	2.83e-17	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
BICEFGKB_01015	1.88e-113	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
BICEFGKB_01016	3.5e-41	XK27_08085	-	-	-	-	-	-	-
BICEFGKB_01017	7.18e-57	-	-	-	L	ko:K07483	-	ko00000	transposase activity
BICEFGKB_01018	2.56e-24	-	-	-	L	-	-	-	Transposase
BICEFGKB_01019	1.34e-69	-	-	-	L	ko:K07497	-	ko00000	Transposase and inactivated derivatives
BICEFGKB_01020	1.08e-36	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_01021	8.78e-238	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BICEFGKB_01022	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BICEFGKB_01023	3.83e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BICEFGKB_01024	1.99e-90	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BICEFGKB_01025	3.12e-184	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
BICEFGKB_01026	4.81e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
BICEFGKB_01027	3.8e-235	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
BICEFGKB_01028	2.24e-152	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
BICEFGKB_01029	1.6e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
BICEFGKB_01030	1.31e-209	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BICEFGKB_01032	1.06e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BICEFGKB_01033	1.22e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BICEFGKB_01034	2.6e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
BICEFGKB_01035	1.14e-98	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
BICEFGKB_01036	1.54e-67	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
BICEFGKB_01037	9.32e-106	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BICEFGKB_01038	2.43e-47	-	-	-	S	-	-	-	MORN repeat protein
BICEFGKB_01039	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
BICEFGKB_01040	4.19e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BICEFGKB_01041	4.29e-64	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
BICEFGKB_01042	1.29e-141	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BICEFGKB_01043	1.23e-134	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
BICEFGKB_01044	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BICEFGKB_01045	4.16e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BICEFGKB_01046	1.99e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BICEFGKB_01047	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BICEFGKB_01048	6.12e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BICEFGKB_01049	1.2e-91	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BICEFGKB_01050	4.36e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
BICEFGKB_01051	3.08e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BICEFGKB_01052	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BICEFGKB_01053	3.99e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BICEFGKB_01054	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BICEFGKB_01055	2.03e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BICEFGKB_01056	5.37e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BICEFGKB_01057	1.44e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BICEFGKB_01058	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BICEFGKB_01059	9.94e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BICEFGKB_01060	2e-32	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
BICEFGKB_01061	1.4e-83	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
BICEFGKB_01062	9.03e-295	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BICEFGKB_01063	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BICEFGKB_01064	1.98e-44	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BICEFGKB_01065	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
BICEFGKB_01066	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BICEFGKB_01067	1.57e-80	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BICEFGKB_01068	5.37e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BICEFGKB_01069	2.13e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
BICEFGKB_01070	2.63e-91	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
BICEFGKB_01071	7.69e-18	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
BICEFGKB_01072	1.43e-15	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
BICEFGKB_01073	1.44e-41	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
BICEFGKB_01074	3.56e-133	-	6.3.2.2	-	H	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	ergothioneine biosynthetic process
BICEFGKB_01076	4.93e-211	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
BICEFGKB_01079	2.27e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
BICEFGKB_01080	3.77e-113	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
BICEFGKB_01081	1.08e-28	treR	-	-	K	ko:K03486,ko:K03710	-	ko00000,ko03000	DNA-binding transcription factor activity
BICEFGKB_01082	3.49e-72	treB	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS System
BICEFGKB_01083	3.86e-98	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
BICEFGKB_01084	7.95e-50	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
BICEFGKB_01085	5.55e-70	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
BICEFGKB_01086	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
BICEFGKB_01087	2.28e-84	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
BICEFGKB_01088	5.67e-165	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
BICEFGKB_01089	1.13e-85	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
BICEFGKB_01090	1.36e-39	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	hydroxyacid-oxoacid transhydrogenase activity
BICEFGKB_01091	2.83e-46	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
BICEFGKB_01092	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
BICEFGKB_01093	3.75e-286	norN	-	-	V	-	-	-	Mate efflux family protein
BICEFGKB_01094	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
BICEFGKB_01095	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
BICEFGKB_01096	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
BICEFGKB_01097	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
BICEFGKB_01098	9.67e-99	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
BICEFGKB_01099	2.67e-250	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BICEFGKB_01100	2.04e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BICEFGKB_01101	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
BICEFGKB_01102	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BICEFGKB_01103	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BICEFGKB_01104	9.28e-90	-	-	-	S	-	-	-	cog cog4699
BICEFGKB_01105	3.81e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BICEFGKB_01106	2.48e-193	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
BICEFGKB_01107	4.5e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
BICEFGKB_01108	2.43e-74	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
BICEFGKB_01109	1.9e-11	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
BICEFGKB_01110	2.66e-92	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
BICEFGKB_01111	1.77e-08	-	-	-	-	-	-	-	-
BICEFGKB_01112	2.29e-224	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
BICEFGKB_01113	1.33e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BICEFGKB_01114	4.3e-36	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
BICEFGKB_01115	1.04e-43	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
BICEFGKB_01116	3.39e-44	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
BICEFGKB_01118	1.13e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
BICEFGKB_01119	1.17e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BICEFGKB_01120	6.4e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
BICEFGKB_01122	4.07e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
BICEFGKB_01123	1.3e-145	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BICEFGKB_01124	7e-243	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
BICEFGKB_01125	1.85e-48	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
BICEFGKB_01126	3.13e-86	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BICEFGKB_01127	5.94e-118	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BICEFGKB_01130	8.48e-204	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
BICEFGKB_01131	2.04e-151	-	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, family IA, variant
BICEFGKB_01132	6.92e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BICEFGKB_01133	1.34e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BICEFGKB_01134	3.29e-121	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BICEFGKB_01135	3.13e-150	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
BICEFGKB_01136	1.41e-211	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
BICEFGKB_01137	5.7e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
BICEFGKB_01138	1.12e-97	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BICEFGKB_01139	8.95e-92	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
BICEFGKB_01140	5.49e-10	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
BICEFGKB_01141	4.43e-290	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
BICEFGKB_01142	2.77e-45	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
BICEFGKB_01143	1.24e-26	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
BICEFGKB_01144	1.72e-103	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
BICEFGKB_01145	2.21e-98	-	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
BICEFGKB_01146	8.78e-284	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BICEFGKB_01147	2.3e-16	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
BICEFGKB_01148	5.86e-43	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
BICEFGKB_01149	2.81e-43	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
BICEFGKB_01150	9.62e-116	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
BICEFGKB_01151	3.28e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
BICEFGKB_01152	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BICEFGKB_01153	1.66e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BICEFGKB_01154	1.21e-95	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
BICEFGKB_01155	3.68e-107	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
BICEFGKB_01156	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BICEFGKB_01157	1.3e-293	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
BICEFGKB_01158	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
BICEFGKB_01159	2.38e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BICEFGKB_01160	1.8e-180	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BICEFGKB_01161	8.06e-236	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
BICEFGKB_01164	8.34e-123	repA	-	-	S	-	-	-	Replication initiator protein A
BICEFGKB_01166	1.63e-17	-	-	-	-	-	-	-	-
BICEFGKB_01167	2.17e-49	-	-	-	MU	-	-	-	outer membrane autotransporter barrel domain protein
BICEFGKB_01168	0.0	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BICEFGKB_01169	2.47e-26	-	-	-	-	-	-	-	-
BICEFGKB_01170	2.16e-25	-	-	-	-	-	-	-	-
BICEFGKB_01171	1.58e-126	-	-	-	-	-	-	-	-
BICEFGKB_01172	1.95e-56	-	-	-	S	-	-	-	PrgI family protein
BICEFGKB_01173	0.0	-	-	-	U	-	-	-	Psort location Cytoplasmic, score
BICEFGKB_01174	0.0	-	-	-	M	-	-	-	CHAP domain protein
BICEFGKB_01175	1.14e-127	-	-	-	-	-	-	-	-
BICEFGKB_01176	3.03e-83	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	single-stranded DNA binding
BICEFGKB_01178	4.35e-69	-	-	-	-	-	-	-	-
BICEFGKB_01179	7.37e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
BICEFGKB_01180	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	An automated process has identified a potential problem with this gene model
BICEFGKB_01183	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BICEFGKB_01185	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BICEFGKB_01187	2.68e-36	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
BICEFGKB_01188	0.0	-	-	-	U	-	-	-	relaxase
BICEFGKB_01190	4.77e-112	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
BICEFGKB_01191	4.88e-06	-	-	-	L	ko:K07497	-	ko00000	transposition
BICEFGKB_01192	1.72e-291	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
BICEFGKB_01193	6.6e-114	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
BICEFGKB_01195	2.86e-91	-	-	-	M	-	-	-	Filamentation induced by cAMP protein fic
BICEFGKB_01199	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
BICEFGKB_01200	9.33e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
BICEFGKB_01201	1.9e-109	-	-	-	L	ko:K07491	-	ko00000	Transposase
BICEFGKB_01202	3.77e-54	XK27_03610	-	-	K	-	-	-	Gnat family
BICEFGKB_01203	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
BICEFGKB_01204	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
BICEFGKB_01205	1.95e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
BICEFGKB_01206	7.73e-31	-	-	-	V	-	-	-	Glucan-binding protein C
BICEFGKB_01207	9.18e-12	-	-	-	V	-	-	-	Glucan-binding protein C
BICEFGKB_01209	3.39e-155	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BICEFGKB_01210	1.82e-298	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BICEFGKB_01211	1.96e-114	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
BICEFGKB_01212	5.9e-191	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BICEFGKB_01213	7.22e-74	clcA2	-	-	P	-	-	-	chloride
BICEFGKB_01214	2.1e-69	clcA2	-	-	P	-	-	-	chloride
BICEFGKB_01215	1.28e-159	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
BICEFGKB_01216	1.89e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
BICEFGKB_01217	0.0	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
BICEFGKB_01218	5.44e-174	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
BICEFGKB_01219	2.01e-149	capA	-	-	M	-	-	-	biosynthesis protein
BICEFGKB_01220	1.5e-149	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
BICEFGKB_01221	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
BICEFGKB_01222	3.17e-29	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	group 1 family protein
BICEFGKB_01223	2.41e-108	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
BICEFGKB_01224	9.54e-105	cpsE	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
BICEFGKB_01225	6.48e-104	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
BICEFGKB_01226	3.57e-91	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
BICEFGKB_01227	8.52e-124	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
BICEFGKB_01229	2.04e-35	-	-	-	M	-	-	-	Glycosyl transferase family 2
BICEFGKB_01230	9.57e-218	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
BICEFGKB_01231	7.01e-07	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
BICEFGKB_01232	3.38e-26	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	amidase activity
BICEFGKB_01233	4.34e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BICEFGKB_01234	7.15e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BICEFGKB_01235	2.29e-224	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BICEFGKB_01236	6.89e-189	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
BICEFGKB_01237	3.52e-124	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
BICEFGKB_01238	1.07e-104	-	-	-	S	-	-	-	TraX protein
BICEFGKB_01239	0.000353	-	-	-	S	-	-	-	TraX protein
BICEFGKB_01240	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
BICEFGKB_01242	8.1e-19	dinF	-	-	V	-	-	-	Mate efflux family protein
BICEFGKB_01243	9.2e-25	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
BICEFGKB_01244	6.66e-19	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
BICEFGKB_01245	4.02e-151	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
BICEFGKB_01246	9.83e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
BICEFGKB_01249	2.95e-104	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
BICEFGKB_01250	2.78e-24	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
BICEFGKB_01251	1.98e-10	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
BICEFGKB_01252	1.61e-249	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
BICEFGKB_01253	2.72e-184	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
BICEFGKB_01254	2.11e-69	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
BICEFGKB_01255	3.17e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
BICEFGKB_01256	2.69e-127	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
BICEFGKB_01257	9.28e-15	-	-	-	-	-	-	-	-
BICEFGKB_01258	6.38e-141	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
BICEFGKB_01259	4e-141	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_01260	5.73e-123	-	-	-	V	-	-	-	VanZ like family
BICEFGKB_01261	1.41e-43	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
BICEFGKB_01262	8.11e-131	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
BICEFGKB_01263	3.77e-251	XK27_12525	-	-	S	-	-	-	hmm pf01594
BICEFGKB_01264	5.38e-36	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
BICEFGKB_01265	3.58e-86	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BICEFGKB_01266	6.88e-58	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	beta-glucosidase activity
BICEFGKB_01267	3.34e-52	-	-	-	S	-	-	-	granule-associated protein
BICEFGKB_01268	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
BICEFGKB_01269	3.14e-38	-	-	-	E	-	-	-	Lysophospholipase L1 and related esterases
BICEFGKB_01270	1.62e-49	-	-	-	E	-	-	-	GDSL-like protein
BICEFGKB_01271	3.56e-199	-	-	-	S	-	-	-	Phospholipase, patatin family
BICEFGKB_01272	4.49e-162	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
BICEFGKB_01273	1.12e-31	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
BICEFGKB_01274	5.27e-32	dacA1	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BICEFGKB_01275	7.09e-273	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BICEFGKB_01276	3.31e-162	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BICEFGKB_01277	1.2e-299	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BICEFGKB_01278	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
BICEFGKB_01279	5.07e-235	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
BICEFGKB_01280	3.38e-232	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
BICEFGKB_01281	2.47e-274	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
BICEFGKB_01282	2.69e-14	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
BICEFGKB_01283	1.15e-110	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
BICEFGKB_01284	1.27e-53	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
BICEFGKB_01285	1.46e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
BICEFGKB_01287	4.39e-306	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
BICEFGKB_01288	2.66e-74	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
BICEFGKB_01290	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BICEFGKB_01291	1.07e-120	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BICEFGKB_01292	5.02e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BICEFGKB_01293	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
BICEFGKB_01294	6.47e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BICEFGKB_01295	6.31e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BICEFGKB_01296	5.02e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BICEFGKB_01297	9.59e-103	alkD	-	-	L	-	-	-	Dna alkylation repair
BICEFGKB_01298	3.2e-121	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
BICEFGKB_01299	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
BICEFGKB_01300	2.83e-99	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
BICEFGKB_01301	8.37e-108	-	-	-	S	-	-	-	Putative small multi-drug export protein
BICEFGKB_01302	1e-231	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BICEFGKB_01303	1.01e-175	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
BICEFGKB_01305	6.78e-221	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
BICEFGKB_01307	7.42e-44	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_01308	1.13e-125	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
BICEFGKB_01309	1.19e-71	badR	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
BICEFGKB_01310	1.99e-48	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
BICEFGKB_01311	2.81e-298	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
BICEFGKB_01312	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BICEFGKB_01332	6.73e-145	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
BICEFGKB_01333	3.3e-237	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
BICEFGKB_01334	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BICEFGKB_01335	2.18e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
BICEFGKB_01336	8.61e-97	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
BICEFGKB_01337	1.63e-187	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
BICEFGKB_01338	2.18e-120	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
BICEFGKB_01339	5.68e-235	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
BICEFGKB_01340	7.65e-61	-	-	-	S	-	-	-	double-stranded DNA endodeoxyribonuclease activity
BICEFGKB_01341	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
BICEFGKB_01342	9.61e-167	-	-	-	S	-	-	-	Protein conserved in bacteria
BICEFGKB_01343	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
BICEFGKB_01344	2.13e-151	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain protein
BICEFGKB_01346	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01349	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
BICEFGKB_01350	2.26e-167	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
BICEFGKB_01351	1.03e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
BICEFGKB_01352	9.97e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
BICEFGKB_01353	9.47e-144	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BICEFGKB_01354	1.14e-35	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
BICEFGKB_01355	1.99e-196	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
BICEFGKB_01356	2.49e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BICEFGKB_01357	1.45e-149	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
BICEFGKB_01358	2.11e-220	-	-	-	S	ko:K07025	-	ko00000	hydrolase
BICEFGKB_01359	1.59e-28	-	-	-	-	-	-	-	-
BICEFGKB_01360	2.87e-75	-	-	-	M	-	-	-	LysM domain
BICEFGKB_01361	5.37e-20	-	-	-	M	-	-	-	LysM domain
BICEFGKB_01362	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
BICEFGKB_01363	1.28e-11	-	-	-	S	-	-	-	Type-A lantibiotic
BICEFGKB_01365	0.0	lcnDR2	-	-	V	-	-	-	Domain of unknown function (DUF4135)
BICEFGKB_01366	0.0	-	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BICEFGKB_01367	5.34e-213	bcrA	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01368	4.56e-167	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
BICEFGKB_01369	2.25e-158	-	-	-	S	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
BICEFGKB_01370	4.08e-47	xre	-	-	K	-	-	-	transcriptional
BICEFGKB_01371	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
BICEFGKB_01372	9.08e-72	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
BICEFGKB_01373	5.56e-124	-	-	-	-	-	-	-	-
BICEFGKB_01374	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01375	4.26e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01376	1e-21	-	-	-	-	-	-	-	-
BICEFGKB_01377	2.64e-36	-	-	-	-	-	-	-	-
BICEFGKB_01379	1.37e-13	-	-	-	-	-	-	-	-
BICEFGKB_01380	1.02e-93	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
BICEFGKB_01381	1.68e-168	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01382	4.26e-229	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
BICEFGKB_01383	8.46e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
BICEFGKB_01384	1.46e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BICEFGKB_01386	9.59e-289	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
BICEFGKB_01387	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
BICEFGKB_01388	8.66e-83	XK27_02560	-	-	S	-	-	-	cog cog2151
BICEFGKB_01389	1.41e-80	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
BICEFGKB_01390	8.48e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
BICEFGKB_01391	1.21e-156	-	-	-	K	-	-	-	transcriptional regulator, MerR family
BICEFGKB_01392	5.39e-62	-	-	-	L	-	-	-	transposase activity
BICEFGKB_01393	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BICEFGKB_01394	8.77e-56	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-Shock Protein
BICEFGKB_01395	5.31e-44	-	-	-	K	-	-	-	Cold shock protein domain
BICEFGKB_01396	9.64e-38	-	-	-	-	-	-	-	-
BICEFGKB_01398	1.56e-38	-	-	-	L	ko:K07483	-	ko00000	transposase activity
BICEFGKB_01399	1.27e-81	-	-	-	L	ko:K07498	-	ko00000	DDE domain
BICEFGKB_01400	6.4e-55	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BICEFGKB_01401	4.57e-99	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BICEFGKB_01402	8.66e-31	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BICEFGKB_01403	3.43e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
BICEFGKB_01404	3.04e-232	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
BICEFGKB_01405	1.2e-208	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
BICEFGKB_01406	7.05e-172	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
BICEFGKB_01407	3.4e-21	-	-	-	D	-	-	-	nuclear chromosome segregation
BICEFGKB_01408	3.68e-205	-	-	-	E	-	-	-	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds
BICEFGKB_01410	1.16e-265	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
BICEFGKB_01411	7.45e-158	-	4.1.3.17	-	H	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	ko00000,ko00001,ko01000	Methyltransferase
BICEFGKB_01412	9.52e-197	-	-	-	S	-	-	-	metal-dependent hydrolase with the TIM-barrel fold
BICEFGKB_01413	3.85e-90	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
BICEFGKB_01414	9.04e-205	yrdR	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
BICEFGKB_01415	2.09e-15	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
BICEFGKB_01416	4.32e-13	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
BICEFGKB_01417	6.72e-29	-	-	-	L	ko:K07497	-	ko00000	overlaps another CDS with the same product name
BICEFGKB_01418	2.22e-174	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
BICEFGKB_01419	5.99e-303	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
BICEFGKB_01421	5.03e-311	mesE	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	Transport protein ComB
BICEFGKB_01422	0.0	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
BICEFGKB_01423	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01424	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01426	2.82e-122	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
BICEFGKB_01427	7.84e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
BICEFGKB_01428	3.68e-134	yutD	-	-	J	-	-	-	protein conserved in bacteria
BICEFGKB_01429	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BICEFGKB_01431	2.75e-304	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BICEFGKB_01432	8.08e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BICEFGKB_01433	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
BICEFGKB_01434	3.89e-62	ftsL	-	-	D	-	-	-	cell division protein FtsL
BICEFGKB_01435	1.54e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BICEFGKB_01436	6.56e-84	-	-	-	-	-	-	-	-
BICEFGKB_01437	2.52e-34	-	-	-	-	-	-	-	-
BICEFGKB_01438	4.3e-54	-	-	-	-	-	-	-	-
BICEFGKB_01439	1.58e-42	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
BICEFGKB_01440	2.06e-31	-	-	-	D	-	-	-	nuclear chromosome segregation
BICEFGKB_01441	8.59e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BICEFGKB_01442	1.01e-181	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BICEFGKB_01443	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
BICEFGKB_01444	2.59e-172	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01445	2.08e-16	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
BICEFGKB_01446	5.04e-127	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
BICEFGKB_01447	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
BICEFGKB_01448	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BICEFGKB_01449	1.53e-70	-	-	-	S	-	-	-	membrane
BICEFGKB_01450	3.76e-13	XK27_02470	-	-	K	-	-	-	LytTr DNA-binding domain protein
BICEFGKB_01451	6.77e-64	-	-	-	KT	-	-	-	response to antibiotic
BICEFGKB_01452	1.35e-13	-	-	-	KT	-	-	-	response to antibiotic
BICEFGKB_01453	6.48e-22	-	-	-	KT	-	-	-	response to antibiotic
BICEFGKB_01454	6.94e-126	yebC	-	-	M	-	-	-	Membrane
BICEFGKB_01455	4.09e-24	yebC	-	-	M	-	-	-	Membrane
BICEFGKB_01456	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
BICEFGKB_01457	8.08e-223	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
BICEFGKB_01458	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BICEFGKB_01459	1.72e-246	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BICEFGKB_01460	1.23e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BICEFGKB_01461	2.89e-251	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BICEFGKB_01462	2.03e-251	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BICEFGKB_01463	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BICEFGKB_01465	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
BICEFGKB_01466	3.77e-166	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
BICEFGKB_01467	3.69e-159	-	-	-	L	ko:K07498	-	ko00000	DDE domain
BICEFGKB_01468	3.17e-43	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
BICEFGKB_01469	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_01470	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
BICEFGKB_01471	2.47e-225	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional
BICEFGKB_01472	3.79e-96	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BICEFGKB_01473	9.01e-81	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
BICEFGKB_01474	6.05e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BICEFGKB_01475	5.83e-109	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
BICEFGKB_01476	1.19e-255	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
BICEFGKB_01479	1.24e-15	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
BICEFGKB_01480	6.83e-76	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
BICEFGKB_01486	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BICEFGKB_01487	8.18e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
BICEFGKB_01488	5.91e-159	-	-	-	S	-	-	-	Pfam PF06570
BICEFGKB_01490	2.03e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BICEFGKB_01491	2.07e-118	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BICEFGKB_01492	2.56e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
BICEFGKB_01493	1.96e-50	XK27_05745	-	-	-	-	-	-	-
BICEFGKB_01494	5.32e-290	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
BICEFGKB_01498	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BICEFGKB_01499	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BICEFGKB_01500	3.39e-121	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
BICEFGKB_01501	5.78e-19	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BICEFGKB_01502	4.7e-206	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BICEFGKB_01503	3.19e-146	spi	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
BICEFGKB_01504	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BICEFGKB_01505	1.91e-63	azlD	-	-	E	-	-	-	branched-chain amino acid
BICEFGKB_01506	7.55e-150	XK27_12120	-	-	E	-	-	-	AzlC protein
BICEFGKB_01507	1.64e-238	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BICEFGKB_01508	1.54e-96	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
BICEFGKB_01509	1.38e-155	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
BICEFGKB_01510	6.45e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
BICEFGKB_01511	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BICEFGKB_01512	3.96e-54	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
BICEFGKB_01514	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
BICEFGKB_01515	1.12e-83	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
BICEFGKB_01516	1.08e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
BICEFGKB_01517	1.94e-16	-	-	-	-	-	-	-	-
BICEFGKB_01518	3.18e-281	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
BICEFGKB_01519	5.35e-292	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
BICEFGKB_01520	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
BICEFGKB_01521	3.86e-34	-	-	-	-	-	-	-	-
BICEFGKB_01522	3.52e-58	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
BICEFGKB_01523	1.79e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives
BICEFGKB_01524	7e-53	-	-	-	L	-	-	-	transposition
BICEFGKB_01529	1.11e-210	blpT	-	-	-	-	-	-	-
BICEFGKB_01530	1.31e-63	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
BICEFGKB_01533	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BICEFGKB_01534	7.59e-212	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
BICEFGKB_01535	9.96e-198	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BICEFGKB_01536	5.68e-258	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BICEFGKB_01537	2.34e-212	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_01538	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_01539	1.67e-293	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
BICEFGKB_01540	3.96e-253	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
BICEFGKB_01541	9.85e-248	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
BICEFGKB_01542	1.25e-115	flaR	-	-	F	-	-	-	topology modulation protein
BICEFGKB_01543	1.93e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BICEFGKB_01546	3.37e-249	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
BICEFGKB_01547	1.45e-73	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
BICEFGKB_01548	9.24e-88	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
BICEFGKB_01549	7.08e-275	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
BICEFGKB_01550	3.75e-305	wzx	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
BICEFGKB_01551	4.92e-112	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01552	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	haloacid dehalogenase-like hydrolase
BICEFGKB_01553	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01554	5.17e-129	-	-	-	-	-	-	-	-
BICEFGKB_01555	7.53e-33	-	-	-	S	-	-	-	Small integral membrane protein
BICEFGKB_01556	1.03e-113	-	-	-	M	-	-	-	Protein conserved in bacteria
BICEFGKB_01557	1.17e-34	-	-	-	K	-	-	-	CsbD-like
BICEFGKB_01558	1.58e-139	XK27_06885	-	-	L	-	-	-	hydrolase
BICEFGKB_01559	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01560	9.99e-65	-	-	-	L	ko:K07498	-	ko00000	Transposase IS66 family
BICEFGKB_01561	1.13e-85	dhaL	2.7.1.121	-	G	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dihydroxyacetone kinase
BICEFGKB_01562	3.03e-314	-	-	-	G	-	-	-	polysaccharide deacetylase
BICEFGKB_01563	2.03e-41	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
BICEFGKB_01564	1.61e-274	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
BICEFGKB_01565	2.09e-51	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
BICEFGKB_01566	7.95e-59	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BICEFGKB_01567	8.01e-125	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
BICEFGKB_01568	5.02e-294	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
BICEFGKB_01569	2.86e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
BICEFGKB_01570	3e-205	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
BICEFGKB_01571	2.79e-111	ccl	-	-	S	-	-	-	cog cog4708
BICEFGKB_01572	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BICEFGKB_01573	1.91e-237	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
BICEFGKB_01574	7.82e-154	-	-	-	L	-	-	-	Transposase DDE domain
BICEFGKB_01575	1.22e-97	-	-	-	S	-	-	-	QueT transporter
BICEFGKB_01576	9.9e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
BICEFGKB_01577	6.55e-220	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
BICEFGKB_01578	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
BICEFGKB_01579	9.09e-50	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
BICEFGKB_01580	1.93e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
BICEFGKB_01581	0.0	ydaO	-	-	E	-	-	-	amino acid
BICEFGKB_01582	1.17e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
BICEFGKB_01583	1.29e-188	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BICEFGKB_01584	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
BICEFGKB_01585	2.48e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BICEFGKB_01586	7.94e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BICEFGKB_01587	4.06e-219	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
BICEFGKB_01588	1.38e-272	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BICEFGKB_01589	2e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
BICEFGKB_01590	1.79e-171	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
BICEFGKB_01591	3.44e-263	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
BICEFGKB_01592	1.85e-05	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
BICEFGKB_01593	5.93e-26	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
BICEFGKB_01594	7.47e-117	-	-	-	-	-	-	-	-
BICEFGKB_01595	1.28e-139	-	-	-	-	-	-	-	-
BICEFGKB_01597	8.81e-114	-	-	-	L	ko:K07483	-	ko00000	transposase activity
BICEFGKB_01598	1.88e-194	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_01599	2.95e-204	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
BICEFGKB_01601	0.0	-	-	-	I	-	-	-	radical SAM domain protein
BICEFGKB_01602	6.25e-227	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
BICEFGKB_01603	9.95e-138	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
BICEFGKB_01604	2.93e-10	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
BICEFGKB_01605	2.18e-211	-	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MatE
BICEFGKB_01606	2.84e-17	-	-	-	-	-	-	-	-
BICEFGKB_01607	5.69e-12	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
BICEFGKB_01608	2.98e-41	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BICEFGKB_01609	1.31e-67	-	-	-	S	-	-	-	Toxin-antitoxin system, toxin component, RelE family
BICEFGKB_01611	1.13e-98	-	-	-	S	-	-	-	ASCH
BICEFGKB_01612	6.31e-17	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
BICEFGKB_01613	6.19e-91	XK27_08050	-	-	O	-	-	-	stress-induced mitochondrial fusion
BICEFGKB_01614	1.61e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
BICEFGKB_01615	1.58e-16	-	-	-	GK	-	-	-	ROK family
BICEFGKB_01616	2.99e-59	-	-	-	GK	-	-	-	ROK family
BICEFGKB_01617	2.09e-266	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BICEFGKB_01618	5.63e-136	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
BICEFGKB_01619	2.15e-280	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BICEFGKB_01620	4.23e-73	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
BICEFGKB_01621	3.55e-79	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
BICEFGKB_01623	4.04e-77	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
BICEFGKB_01624	2.27e-151	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	effector of murein hydrolase
BICEFGKB_01625	3.33e-126	-	-	-	S	-	-	-	IA, variant 1
BICEFGKB_01626	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BICEFGKB_01627	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BICEFGKB_01628	9.75e-145	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
BICEFGKB_01630	1.55e-195	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
BICEFGKB_01632	6.11e-68	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
BICEFGKB_01633	1.25e-85	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
BICEFGKB_01635	0.000322	MA20_01270	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
BICEFGKB_01636	3.02e-171	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
BICEFGKB_01637	9.86e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
BICEFGKB_01638	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BICEFGKB_01639	1.84e-24	XK27_00735	-	-	-	-	-	-	-
BICEFGKB_01640	1.44e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_01641	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
BICEFGKB_01642	5.12e-42	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
BICEFGKB_01643	5.27e-104	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
BICEFGKB_01645	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BICEFGKB_01646	2.15e-109	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
BICEFGKB_01647	2.08e-181	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
BICEFGKB_01648	6.24e-175	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
BICEFGKB_01649	3.74e-265	arcT	-	-	E	-	-	-	Aminotransferase
BICEFGKB_01650	9.99e-176	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
BICEFGKB_01651	1.01e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
BICEFGKB_01652	1.98e-63	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BICEFGKB_01653	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BICEFGKB_01654	3.03e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BICEFGKB_01655	4.86e-74	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
BICEFGKB_01656	6.25e-217	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
BICEFGKB_01657	1.5e-312	-	-	-	-	-	-	-	-
BICEFGKB_01658	1.9e-207	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BICEFGKB_01659	1.69e-161	-	-	-	S	-	-	-	Glycosyl transferase family 2
BICEFGKB_01660	3.81e-64	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
BICEFGKB_01661	1.15e-280	rgpX3	-	-	S	-	-	-	polysaccharide biosynthetic process
BICEFGKB_01662	9.05e-235	tagF	2.7.8.12	-	M	ko:K09809,ko:K19046	-	ko00000,ko01000,ko02048	Glycosyl transferase, family 2
BICEFGKB_01663	9.24e-171	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
BICEFGKB_01664	6.64e-285	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
BICEFGKB_01665	1.83e-230	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
BICEFGKB_01666	4.54e-183	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
BICEFGKB_01667	2.09e-287	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
BICEFGKB_01668	5.39e-251	rgpE	-	GT2	M	ko:K12998	-	ko00000,ko01000,ko01003,ko01005	COG0463 Glycosyltransferases involved in cell wall biogenesis
BICEFGKB_01669	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
BICEFGKB_01670	4.62e-154	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
BICEFGKB_01671	2.57e-157	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
BICEFGKB_01672	2.24e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BICEFGKB_01673	1.46e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
BICEFGKB_01674	1.12e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
BICEFGKB_01675	8.64e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BICEFGKB_01676	5.5e-134	yjbK	-	-	S	-	-	-	Adenylate cyclase
BICEFGKB_01677	2.02e-154	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
BICEFGKB_01678	4.66e-195	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BICEFGKB_01679	4.44e-221	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
BICEFGKB_01680	1.28e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
BICEFGKB_01681	1.57e-136	-	-	-	E	-	-	-	LysE type translocator
BICEFGKB_01682	3.9e-85	-	-	-	IQ	-	-	-	PFAM AMP-dependent synthetase and ligase
BICEFGKB_01686	0.000313	-	-	-	-	-	-	-	-
BICEFGKB_01687	1.08e-34	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
BICEFGKB_01688	2.56e-26	-	-	-	L	ko:K07485	-	ko00000	Transposase for ISSha1
BICEFGKB_01689	1.75e-63	-	-	-	U	-	-	-	response to pH
BICEFGKB_01690	3.37e-137	-	-	-	L	ko:K07485	-	ko00000	Transposase
BICEFGKB_01691	1.16e-110	pppA	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
BICEFGKB_01692	4.19e-289	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
BICEFGKB_01693	5.24e-185	-	-	-	S	-	-	-	Macro domain protein
BICEFGKB_01694	1.62e-14	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
BICEFGKB_01695	3.38e-72	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
BICEFGKB_01696	1.05e-113	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BICEFGKB_01697	2.85e-214	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
BICEFGKB_01698	4.71e-287	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
BICEFGKB_01699	8.88e-126	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
BICEFGKB_01700	4.13e-15	-	-	-	C	ko:K06871	-	ko00000	Arylsulfatase regulator (Fe-S oxidoreductase)
BICEFGKB_01701	2.39e-11	-	-	-	-	-	-	-	-
BICEFGKB_01702	9.8e-41	-	-	-	S	-	-	-	Antidote-toxin recognition MazE, bacterial antitoxin
BICEFGKB_01703	2.75e-91	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Prophage maintenance system killer protein
BICEFGKB_01704	1.33e-23	-	-	-	-	-	-	-	-
BICEFGKB_01705	1.82e-173	ermA	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylase
BICEFGKB_01706	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
BICEFGKB_01707	2.74e-235	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BICEFGKB_01708	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
BICEFGKB_01709	3.86e-192	XK27_00020	-	-	J	-	-	-	Belongs to the SUA5 family
BICEFGKB_01710	2.76e-146	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BICEFGKB_01711	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BICEFGKB_01712	1.64e-57	ysdA	-	-	L	-	-	-	Membrane
BICEFGKB_01713	7.51e-242	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
BICEFGKB_01714	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BICEFGKB_01715	3.05e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BICEFGKB_01716	2.31e-230	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
BICEFGKB_01718	1.54e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BICEFGKB_01719	1.11e-119	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
BICEFGKB_01720	8.45e-111	ypmR	-	-	E	-	-	-	lipolytic protein G-D-S-L family
BICEFGKB_01721	3.28e-57	XK27_03630	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related esterases
BICEFGKB_01722	2.29e-188	WQ51_01275	-	-	S	-	-	-	DegV family
BICEFGKB_01723	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
BICEFGKB_01724	5.12e-96	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
BICEFGKB_01725	3.85e-201	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
BICEFGKB_01726	1.64e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
BICEFGKB_01727	1.72e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
BICEFGKB_01728	3.69e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BICEFGKB_01731	3.81e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BICEFGKB_01732	7.42e-162	dnaD	-	-	-	ko:K02086	-	ko00000	-
BICEFGKB_01733	2.81e-232	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BICEFGKB_01734	6.44e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BICEFGKB_01735	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
BICEFGKB_01736	2.12e-177	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
BICEFGKB_01737	4.43e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BICEFGKB_01738	2.71e-150	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
BICEFGKB_01739	6.73e-285	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BICEFGKB_01740	1.61e-308	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
BICEFGKB_01741	5.16e-66	hisE	3.5.4.19, 3.6.1.31, 5.3.1.16	-	E	ko:K01523,ko:K01814,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
BICEFGKB_01742	4.95e-79	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BICEFGKB_01743	3.13e-173	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
BICEFGKB_01744	7.66e-163	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BICEFGKB_01745	3.88e-140	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BICEFGKB_01746	3.35e-137	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
BICEFGKB_01747	8.41e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BICEFGKB_01748	3.99e-149	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
BICEFGKB_01749	5.26e-234	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BICEFGKB_01750	4.1e-250	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BICEFGKB_01751	7.37e-60	-	-	-	L	ko:K07483	-	ko00000	Transposase
BICEFGKB_01752	2.84e-203	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
BICEFGKB_01753	2.63e-176	-	-	-	S	-	-	-	dextransucrase activity
BICEFGKB_01754	5.1e-47	-	-	-	S	-	-	-	dextransucrase activity
BICEFGKB_01755	5e-19	-	-	-	S	-	-	-	dextransucrase activity
BICEFGKB_01756	3.48e-84	-	-	-	S	-	-	-	dextransucrase activity
BICEFGKB_01757	3.24e-294	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
BICEFGKB_01758	5.5e-34	csbD	-	-	K	-	-	-	CsbD-like
BICEFGKB_01759	3.23e-75	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
BICEFGKB_01760	2.22e-85	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
BICEFGKB_01761	9.88e-300	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
BICEFGKB_01762	2.01e-241	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BICEFGKB_01763	9.26e-317	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
BICEFGKB_01764	1.48e-153	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
BICEFGKB_01765	4.96e-86	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
BICEFGKB_01766	2.47e-100	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BICEFGKB_01767	2.13e-158	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BICEFGKB_01768	1.2e-215	-	-	-	T	-	-	-	Histidine kinase
BICEFGKB_01769	6.05e-171	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
BICEFGKB_01770	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
BICEFGKB_01771	7.82e-128	-	-	-	S	ko:K06940	-	ko00000	Fe-S-cluster oxidoreductase
BICEFGKB_01774	7.76e-33	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
BICEFGKB_01775	1.77e-158	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
BICEFGKB_01777	3.03e-55	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
BICEFGKB_01778	1.23e-194	mutR	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
BICEFGKB_01779	0.0	-	2.7.7.73, 2.7.7.80	-	E	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	metalloendopeptidase activity
BICEFGKB_01780	9.22e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
BICEFGKB_01784	1.02e-203	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01785	1.18e-169	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
BICEFGKB_01786	2.88e-236	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BICEFGKB_01787	8.09e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
BICEFGKB_01788	1.13e-76	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
BICEFGKB_01789	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BICEFGKB_01790	1.2e-262	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
BICEFGKB_01791	0.0	-	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
BICEFGKB_01792	3.07e-134	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_01793	2.63e-212	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
BICEFGKB_01794	3.14e-177	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01795	1.24e-121	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BICEFGKB_01796	6.99e-26	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
BICEFGKB_01797	3.72e-48	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
BICEFGKB_01798	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BICEFGKB_01799	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BICEFGKB_01800	7.74e-103	-	-	-	L	-	-	-	Resolvase, N terminal domain
BICEFGKB_01801	4.17e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
BICEFGKB_01808	2.74e-84	WQ51_03320	-	-	S	-	-	-	cog cog4835
BICEFGKB_01809	4.48e-57	-	-	-	S	-	-	-	EDD domain protein, DegV family
BICEFGKB_01810	5.47e-111	degV	-	-	T	-	-	-	EDD domain protein, DegV family
BICEFGKB_01811	1.05e-177	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BICEFGKB_01812	2.33e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BICEFGKB_01813	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
BICEFGKB_01814	2.24e-27	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
BICEFGKB_01815	1.7e-179	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
BICEFGKB_01816	3.47e-265	nadR	-	-	H	-	-	-	adenylyltransferase
BICEFGKB_01817	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
BICEFGKB_01818	1.3e-90	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
BICEFGKB_01819	1.04e-99	-	-	-	K	-	-	-	DNA-binding transcription factor activity
BICEFGKB_01820	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
BICEFGKB_01821	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
BICEFGKB_01822	1.33e-63	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
BICEFGKB_01823	6.08e-36	-	2.7.6.5	-	S	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
BICEFGKB_01824	1.19e-36	-	2.7.6.5	-	S	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
BICEFGKB_01825	4.08e-41	dltr	-	-	T	-	-	-	response regulator
BICEFGKB_01826	8.01e-37	dltr	-	-	T	-	-	-	response regulator
BICEFGKB_01827	2.55e-07	sptS	-	-	T	-	-	-	Histidine kinase
BICEFGKB_01828	9.14e-18	sptS	-	-	T	-	-	-	Histidine kinase
BICEFGKB_01829	7.05e-138	sptS	-	-	T	-	-	-	Histidine kinase
BICEFGKB_01830	9.7e-169	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
BICEFGKB_01831	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BICEFGKB_01832	3.36e-206	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
BICEFGKB_01833	3.3e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
BICEFGKB_01834	1.79e-184	usp	3.5.1.104, 3.5.1.28	CBM50	S	ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409	ko05133,map05133	ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000	pathogenesis
BICEFGKB_01835	1.46e-84	sip	-	-	M	-	-	-	LysM domain protein
BICEFGKB_01836	1.85e-243	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
BICEFGKB_01840	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BICEFGKB_01841	1.47e-210	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
BICEFGKB_01842	3.31e-238	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
BICEFGKB_01843	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
BICEFGKB_01844	1.38e-163	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
BICEFGKB_01845	2.85e-224	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
BICEFGKB_01846	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BICEFGKB_01847	4.52e-185	-	-	-	M	-	-	-	GBS Bsp-like repeat
BICEFGKB_01848	1.28e-70	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
BICEFGKB_01849	3.78e-38	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
BICEFGKB_01850	1.29e-186	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
BICEFGKB_01851	4.75e-289	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
BICEFGKB_01852	1.12e-242	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BICEFGKB_01853	4.21e-285	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BICEFGKB_01854	2.98e-163	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
BICEFGKB_01855	8.83e-265	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
BICEFGKB_01856	3.71e-186	icaB	-	-	G	-	-	-	deacetylase
BICEFGKB_01857	1.47e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
BICEFGKB_01858	3.25e-192	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BICEFGKB_01859	1.04e-192	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
BICEFGKB_01861	2.62e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
BICEFGKB_01862	3.5e-127	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BICEFGKB_01863	2.69e-124	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
BICEFGKB_01864	3.73e-06	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
BICEFGKB_01865	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BICEFGKB_01866	2.91e-23	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BICEFGKB_01867	1.81e-159	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
BICEFGKB_01868	3.44e-100	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase F(0) sector subunit b
BICEFGKB_01869	4.27e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BICEFGKB_01870	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BICEFGKB_01871	4.5e-202	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BICEFGKB_01872	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BICEFGKB_01873	6e-77	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
BICEFGKB_01874	1.94e-290	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
BICEFGKB_01875	1.59e-285	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BICEFGKB_01876	4.44e-173	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BICEFGKB_01877	4.86e-142	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BICEFGKB_01878	4.86e-201	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
BICEFGKB_01879	2.45e-178	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
BICEFGKB_01880	5.73e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
BICEFGKB_01881	7.25e-206	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BICEFGKB_01882	7.24e-102	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
BICEFGKB_01883	9.32e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
BICEFGKB_01884	6.47e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BICEFGKB_01885	2.92e-116	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BICEFGKB_01886	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BICEFGKB_01887	5.89e-108	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
BICEFGKB_01888	5.14e-105	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
BICEFGKB_01889	1.22e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
BICEFGKB_01890	1.23e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
BICEFGKB_01891	4.68e-62	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BICEFGKB_01892	3.86e-53	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BICEFGKB_01893	6.6e-28	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BICEFGKB_01894	1.66e-302	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BICEFGKB_01895	3.37e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
BICEFGKB_01896	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BICEFGKB_01897	2.35e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BICEFGKB_01898	1.79e-11	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
BICEFGKB_01899	1.93e-33	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
BICEFGKB_01900	9.76e-23	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
BICEFGKB_01901	6.11e-54	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
BICEFGKB_01902	9.52e-303	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BICEFGKB_01903	2.96e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BICEFGKB_01904	4e-147	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
BICEFGKB_01905	5.23e-258	XK27_00055	-	-	P	-	-	-	Major Facilitator
BICEFGKB_01906	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BICEFGKB_01907	8.47e-126	-	-	-	V	-	-	-	VanZ like family
BICEFGKB_01908	7.59e-10	-	-	-	D	-	-	-	nuclear chromosome segregation
BICEFGKB_01910	3e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_01911	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
BICEFGKB_01912	1.24e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
BICEFGKB_01913	4.29e-174	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BICEFGKB_01914	5.68e-245	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
BICEFGKB_01915	1.82e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
BICEFGKB_01916	5.93e-299	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
BICEFGKB_01917	9.85e-302	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BICEFGKB_01918	2.39e-96	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
BICEFGKB_01919	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
BICEFGKB_01920	4.23e-23	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BICEFGKB_01921	1.64e-179	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BICEFGKB_01922	1.6e-36	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BICEFGKB_01924	3.34e-77	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BICEFGKB_01925	3.31e-240	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BICEFGKB_01926	1.92e-213	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BICEFGKB_01927	3.08e-09	-	-	-	-	-	-	-	-
BICEFGKB_01928	5.48e-201	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BICEFGKB_01929	4.87e-234	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BICEFGKB_01930	1.06e-163	-	-	-	K	ko:K20374,ko:K21405	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
BICEFGKB_01931	1.02e-130	-	-	-	KLT	-	-	-	serine threonine protein kinase
BICEFGKB_01932	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
BICEFGKB_01933	1.03e-284	-	-	-	EGP	-	-	-	Major facilitator Superfamily
BICEFGKB_01934	1.28e-94	adcR	-	-	K	-	-	-	transcriptional
BICEFGKB_01935	8.76e-176	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BICEFGKB_01936	7.36e-165	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_01937	2.93e-208	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
BICEFGKB_01938	5.05e-86	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_01939	8.33e-30	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_01940	0.0	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
BICEFGKB_01941	6.69e-200	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
BICEFGKB_01942	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
BICEFGKB_01943	3.22e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
BICEFGKB_01944	9.27e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
BICEFGKB_01945	5.06e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BICEFGKB_01946	5.24e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
BICEFGKB_01947	7.4e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
BICEFGKB_01948	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BICEFGKB_01949	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
BICEFGKB_01950	8.27e-181	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_01951	1.44e-53	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BICEFGKB_01952	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BICEFGKB_01954	4.49e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
BICEFGKB_01955	2.97e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
BICEFGKB_01957	4.42e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
BICEFGKB_01958	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
BICEFGKB_01959	2.91e-227	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
BICEFGKB_01961	4.75e-91	ytxH	-	-	S	-	-	-	General stress protein
BICEFGKB_01962	1.14e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BICEFGKB_01963	5.27e-191	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BICEFGKB_01964	2.26e-215	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BICEFGKB_01965	1.2e-54	WQ51_05770	-	-	KT	-	-	-	PspC domain
BICEFGKB_01966	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
BICEFGKB_01968	1.62e-199	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
BICEFGKB_01969	6.61e-189	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
BICEFGKB_01970	3.04e-236	-	-	-	S	-	-	-	CRISPR-associated protein Csn2 subfamily St
BICEFGKB_01971	8.44e-71	-	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BICEFGKB_01972	1.32e-220	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BICEFGKB_01973	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BICEFGKB_01974	3.1e-124	-	-	-	-	-	-	-	-
BICEFGKB_01975	7.87e-36	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
BICEFGKB_01976	3.24e-40	-	-	-	S	-	-	-	CAAX protease self-immunity
BICEFGKB_01977	7.8e-35	-	-	-	S	-	-	-	CAAX protease self-immunity
BICEFGKB_01978	3.71e-46	-	-	-	-	-	-	-	-
BICEFGKB_01980	4.98e-85	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
BICEFGKB_01981	3.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
BICEFGKB_01983	2.96e-32	tra981A	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
BICEFGKB_01984	1.83e-87	-	-	-	L	ko:K07497	-	ko00000	transposition
BICEFGKB_01985	3.6e-51	-	-	-	L	ko:K07483	-	ko00000	transposase activity
BICEFGKB_01986	0.0	-	-	-	M	-	-	-	family 8
BICEFGKB_01987	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
BICEFGKB_01988	2.21e-91	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
BICEFGKB_01989	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
BICEFGKB_01991	9.13e-190	-	-	-	-	-	-	-	-
BICEFGKB_01992	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BICEFGKB_01993	5.86e-79	-	-	-	-	-	-	-	-
BICEFGKB_01995	5.05e-37	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
BICEFGKB_01996	2.76e-38	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
BICEFGKB_01997	4.43e-71	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
BICEFGKB_01999	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
BICEFGKB_02000	7.53e-229	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
BICEFGKB_02001	2.73e-204	yvgN	-	-	C	-	-	-	reductase
BICEFGKB_02002	3.34e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
BICEFGKB_02003	2.35e-142	ydgI	-	-	C	-	-	-	Nitroreductase
BICEFGKB_02004	2.39e-294	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BICEFGKB_02005	6.9e-199	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
BICEFGKB_02006	4.92e-99	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
BICEFGKB_02007	2.27e-191	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
BICEFGKB_02008	1.16e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
BICEFGKB_02009	2.24e-08	ydhF	-	-	S	-	-	-	Aldo keto reductase
BICEFGKB_02010	8.66e-91	ydhF	-	-	S	-	-	-	Aldo keto reductase
BICEFGKB_02011	1.31e-85	ydhF	-	-	S	-	-	-	Aldo keto reductase
BICEFGKB_02012	9.82e-107	-	-	-	K	-	-	-	WHG domain
BICEFGKB_02013	3.17e-118	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
BICEFGKB_02014	3.87e-28	-	-	-	P	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
BICEFGKB_02015	7.75e-54	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
BICEFGKB_02016	7.97e-108	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
BICEFGKB_02017	1.63e-215	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
BICEFGKB_02018	8.82e-207	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BICEFGKB_02019	6.18e-144	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
BICEFGKB_02020	2.02e-148	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
BICEFGKB_02021	1.81e-173	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BICEFGKB_02025	1.91e-119	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
BICEFGKB_02026	1.13e-102	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
BICEFGKB_02027	1.58e-37	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
BICEFGKB_02028	1.61e-226	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
BICEFGKB_02029	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
BICEFGKB_02030	2.68e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
BICEFGKB_02031	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BICEFGKB_02032	1.56e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BICEFGKB_02033	1.59e-234	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BICEFGKB_02034	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BICEFGKB_02035	1.08e-302	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BICEFGKB_02036	1.62e-158	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BICEFGKB_02037	1.79e-125	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	cell septum assembly
BICEFGKB_02038	3e-45	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
BICEFGKB_02039	6.84e-184	ylmH	-	-	T	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	S4 RNA-binding domain
BICEFGKB_02040	1.4e-184	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division protein DivIVA
BICEFGKB_02041	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BICEFGKB_02042	3.14e-294	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
BICEFGKB_02043	6.81e-309	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
BICEFGKB_02044	1.39e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
BICEFGKB_02045	1.09e-223	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BICEFGKB_02046	1.75e-226	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
BICEFGKB_02047	4.53e-196	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
BICEFGKB_02048	6.18e-238	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BICEFGKB_02049	2.55e-143	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
BICEFGKB_02050	9.23e-247	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BICEFGKB_02051	4.33e-197	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BICEFGKB_02052	1.46e-141	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BICEFGKB_02053	4.15e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BICEFGKB_02054	1.13e-223	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
BICEFGKB_02055	2.21e-128	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
BICEFGKB_02056	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
BICEFGKB_02057	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
BICEFGKB_02058	1.01e-14	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
BICEFGKB_02059	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BICEFGKB_02060	6.93e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
BICEFGKB_02061	7.07e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BICEFGKB_02062	6.04e-309	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BICEFGKB_02063	3.03e-75	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
BICEFGKB_02064	8.68e-25	-	-	-	L	ko:K07483	-	ko00000	transposase activity
BICEFGKB_02065	2.03e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase
BICEFGKB_02066	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
BICEFGKB_02067	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
BICEFGKB_02069	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BICEFGKB_02070	2.18e-211	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
BICEFGKB_02071	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
BICEFGKB_02072	2.62e-121	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
BICEFGKB_02073	4.28e-120	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BICEFGKB_02074	3.82e-157	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
BICEFGKB_02075	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
BICEFGKB_02076	1.33e-151	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
BICEFGKB_02077	1.29e-52	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BICEFGKB_02078	2.72e-156	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase