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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HIGHFHGP_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIGHFHGP_00002	5.94e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIGHFHGP_00003	2.76e-257	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIGHFHGP_00004	3.41e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF721)
HIGHFHGP_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIGHFHGP_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIGHFHGP_00007	1.22e-88	-	-	-	S	-	-	-	Transmembrane domain of unknown function (DUF3566)
HIGHFHGP_00008	4.91e-240	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HIGHFHGP_00009	3.2e-14	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HIGHFHGP_00010	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00011	6.18e-262	-	-	-	V	-	-	-	VanZ like family
HIGHFHGP_00012	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HIGHFHGP_00013	3.64e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HIGHFHGP_00014	4.61e-19	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HIGHFHGP_00017	9.07e-31	-	-	-	L	ko:K07485	-	ko00000	Transposase
HIGHFHGP_00018	1.14e-74	-	-	-	F	-	-	-	Calcineurin-like phosphoesterase
HIGHFHGP_00019	5.8e-105	ptxC	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00020	5.11e-101	-	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00021	8.45e-105	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HIGHFHGP_00022	1.43e-145	-	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HIGHFHGP_00023	1.56e-24	-	-	-	K	-	-	-	Transcriptional regulator, rpir family
HIGHFHGP_00024	4.97e-23	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HIGHFHGP_00025	8.71e-257	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HIGHFHGP_00026	2.91e-186	-	-	-	S	ko:K07043	-	ko00000	Protein of unknown function DUF45
HIGHFHGP_00027	4.38e-55	gntK	2.7.1.12, 2.7.1.71	-	F	ko:K00851,ko:K00891	ko00030,ko00400,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00400,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate kinase
HIGHFHGP_00028	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HIGHFHGP_00029	1.09e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HIGHFHGP_00030	3.43e-298	-	-	-	P	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HIGHFHGP_00031	1.08e-266	-	-	-	S	-	-	-	AAA ATPase domain
HIGHFHGP_00032	2.47e-153	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HIGHFHGP_00033	6.83e-138	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
HIGHFHGP_00034	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HIGHFHGP_00035	0.0	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	ADP-glyceromanno-heptose 6-epimerase activity
HIGHFHGP_00036	9.11e-208	-	-	-	-	-	-	-	-
HIGHFHGP_00037	3.7e-127	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HIGHFHGP_00038	4.56e-270	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2194)
HIGHFHGP_00039	0.0	-	-	GT4	M	ko:K21011	ko02025,map02025	ko00000,ko00001,ko01003	Domain of unknown function (DUF3492)
HIGHFHGP_00040	0.0	-	-	-	S	ko:K21012	ko02025,map02025	ko00000,ko00001	Putative exopolysaccharide Exporter (EPS-E)
HIGHFHGP_00041	0.0	-	-	-	M	ko:K06330	-	ko00000	CotH kinase protein
HIGHFHGP_00042	1.93e-203	-	-	-	P	-	-	-	VTC domain
HIGHFHGP_00043	1.72e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HIGHFHGP_00044	0.0	-	3.1.4.52	-	T	ko:K14051	ko02024,ko02026,map02024,map02026	ko00000,ko00001,ko01000	Putative diguanylate phosphodiesterase
HIGHFHGP_00045	2.3e-121	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HIGHFHGP_00046	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HIGHFHGP_00047	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HIGHFHGP_00048	0.0	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HIGHFHGP_00049	0.0	-	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIGHFHGP_00050	5.87e-93	-	-	-	S	-	-	-	Protein conserved in bacteria
HIGHFHGP_00051	0.0	-	-	-	S	-	-	-	Amidohydrolase family
HIGHFHGP_00052	5.93e-261	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HIGHFHGP_00053	4.19e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF3073)
HIGHFHGP_00054	3.28e-218	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_00055	4.35e-102	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_00056	1.64e-163	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_00057	2.13e-94	-	-	-	I	-	-	-	Sterol carrier protein
HIGHFHGP_00058	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HIGHFHGP_00059	7.56e-48	-	-	-	-	-	-	-	-
HIGHFHGP_00060	3.43e-178	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HIGHFHGP_00061	2.71e-98	crgA	-	-	D	-	-	-	Involved in cell division
HIGHFHGP_00062	1.2e-145	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HIGHFHGP_00063	6e-287	srtB	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HIGHFHGP_00064	6.42e-154	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	para-aminobenzoate synthase glutamine amidotransferase component II
HIGHFHGP_00065	0.0	pknB	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HIGHFHGP_00066	1.88e-222	pknA	2.7.11.1	-	T	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HIGHFHGP_00067	0.0	pbpA	-	-	M	ko:K05364	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HIGHFHGP_00068	0.0	rodA	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HIGHFHGP_00069	0.0	pstP	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Sigma factor PP2C-like phosphatases
HIGHFHGP_00070	1.09e-105	fhaB	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HIGHFHGP_00071	3.54e-165	fhaA	-	-	T	-	-	-	Protein of unknown function (DUF2662)
HIGHFHGP_00072	0.0	pepX	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HIGHFHGP_00073	1.08e-270	pldB	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Serine aminopeptidase, S33
HIGHFHGP_00074	2.86e-118	-	-	-	O	-	-	-	Hsp20/alpha crystallin family
HIGHFHGP_00075	6.58e-228	-	-	-	EG	-	-	-	EamA-like transporter family
HIGHFHGP_00076	1.28e-28	-	-	-	-	-	-	-	-
HIGHFHGP_00077	0.0	-	-	-	S	-	-	-	Putative esterase
HIGHFHGP_00078	0.0	lysX	-	-	S	-	-	-	Uncharacterised conserved protein (DUF2156)
HIGHFHGP_00079	1.49e-255	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIGHFHGP_00080	4.3e-170	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HIGHFHGP_00081	3.8e-252	-	-	-	S	-	-	-	Fic/DOC family
HIGHFHGP_00082	3.14e-177	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HIGHFHGP_00083	2.39e-131	-	-	-	S	-	-	-	Protein of unknown function DUF262
HIGHFHGP_00084	1.01e-68	-	-	-	S	-	-	-	Putative heavy-metal-binding
HIGHFHGP_00085	2.65e-186	-	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HIGHFHGP_00087	0.0	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HIGHFHGP_00088	0.0	degP	-	-	O	ko:K08372	ko02020,map02020	ko00000,ko00001,ko01000,ko01002	Domain present in PSD-95, Dlg, and ZO-1/2.
HIGHFHGP_00089	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HIGHFHGP_00090	0.0	fprA	1.18.1.2, 1.19.1.1	-	C	ko:K00528	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase
HIGHFHGP_00091	3.36e-219	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HIGHFHGP_00093	8.23e-219	-	-	-	EG	-	-	-	EamA-like transporter family
HIGHFHGP_00094	7.69e-253	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
HIGHFHGP_00095	4.79e-309	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIGHFHGP_00096	0.0	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HIGHFHGP_00097	1.88e-198	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIGHFHGP_00098	5.18e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIGHFHGP_00099	3.5e-57	livK	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HIGHFHGP_00100	1.09e-46	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_00101	1.03e-168	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_00102	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Domain of unknown function (DUF1964)
HIGHFHGP_00103	0.0	scrT	-	-	G	-	-	-	Transporter major facilitator family protein
HIGHFHGP_00104	4.91e-242	-	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_00105	0.0	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HIGHFHGP_00106	7.18e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HIGHFHGP_00107	1.76e-260	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HIGHFHGP_00108	2.23e-187	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HIGHFHGP_00109	1.42e-246	-	-	-	K	-	-	-	Transcriptional regulator
HIGHFHGP_00110	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HIGHFHGP_00111	5.28e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HIGHFHGP_00113	0.0	-	-	-	M	-	-	-	cell wall anchor domain protein
HIGHFHGP_00114	0.0	-	-	-	M	-	-	-	domain protein
HIGHFHGP_00115	2.27e-220	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HIGHFHGP_00116	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HIGHFHGP_00117	0.0	malL	2.4.1.4, 3.2.1.1, 3.2.1.20, 5.4.99.16	GH13,GH31	G	ko:K01187,ko:K05341,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HIGHFHGP_00118	4.66e-297	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00119	0.0	malC	-	-	G	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00120	7.8e-208	malG	-	-	G	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00121	0.0	apuB	3.2.1.41, 3.2.1.68	CBM48,GH13	G	ko:K01200,ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HIGHFHGP_00122	6.81e-225	-	-	-	S	ko:K07025	-	ko00000	HAD-hyrolase-like
HIGHFHGP_00123	1.14e-187	traX	-	-	S	-	-	-	TraX protein
HIGHFHGP_00124	3.23e-247	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HIGHFHGP_00125	0.0	-	3.2.1.1, 3.2.1.41	CBM48,GH13	M	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	Aamy_C
HIGHFHGP_00126	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HIGHFHGP_00127	2.49e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIGHFHGP_00128	7.84e-221	dnaJ	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	DnaJ molecular chaperone homology domain
HIGHFHGP_00129	5.76e-134	hspR	-	-	K	ko:K13640	-	ko00000,ko03000	transcriptional regulator, MerR family
HIGHFHGP_00130	5.43e-21	-	-	-	F	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HIGHFHGP_00131	6.78e-143	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
HIGHFHGP_00132	9.22e-181	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HIGHFHGP_00133	3.05e-161	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HIGHFHGP_00134	5.23e-171	dedA1	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HIGHFHGP_00135	7.5e-159	-	-	-	D	-	-	-	bacterial-type flagellum organization
HIGHFHGP_00136	2.54e-243	cpaF	-	-	U	ko:K02283	-	ko00000,ko02035,ko02044	Type II IV secretion system protein
HIGHFHGP_00137	7.27e-95	-	-	-	U	ko:K12510	-	ko00000,ko02044	Type ii secretion system
HIGHFHGP_00138	4.65e-149	-	-	-	NU	-	-	-	Type II secretion system (T2SS), protein F
HIGHFHGP_00139	3.68e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF4244)
HIGHFHGP_00140	9.46e-77	-	-	-	U	-	-	-	TadE-like protein
HIGHFHGP_00141	1.23e-69	-	-	-	S	-	-	-	TIGRFAM helicase secretion neighborhood TadE-like protein
HIGHFHGP_00142	5.18e-273	-	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Diacylglycerol kinase catalytic domain protein
HIGHFHGP_00143	2.69e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_00144	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III subunit gamma tau
HIGHFHGP_00145	9.94e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIGHFHGP_00146	1.31e-75	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HIGHFHGP_00147	8.92e-54	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HIGHFHGP_00148	2.64e-268	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HIGHFHGP_00149	2.39e-85	-	-	-	V	-	-	-	Abi-like protein
HIGHFHGP_00150	9.15e-135	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HIGHFHGP_00151	2.12e-81	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HIGHFHGP_00152	6.3e-174	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HIGHFHGP_00153	6.76e-125	ask	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HIGHFHGP_00154	1.53e-268	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIGHFHGP_00155	1.64e-143	-	-	-	-	-	-	-	-
HIGHFHGP_00156	3.65e-222	-	-	-	L	-	-	-	Domain of unknown function (DUF4862)
HIGHFHGP_00157	9.73e-230	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIGHFHGP_00158	9.84e-162	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HIGHFHGP_00159	5.17e-204	-	3.5.1.106	-	I	ko:K15357	ko00760,ko01120,map00760,map01120	ko00000,ko00001,ko00002,ko01000	carboxylic ester hydrolase activity
HIGHFHGP_00160	1.07e-12	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIGHFHGP_00161	0.0	oppA7	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIGHFHGP_00162	2.11e-204	oppB6	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00163	0.0	oppCD2	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HIGHFHGP_00164	1.13e-186	oppF	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00165	1.5e-230	nanA	4.1.3.3, 4.3.3.7	-	EM	ko:K01639,ko:K01714	ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
HIGHFHGP_00166	2.13e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIGHFHGP_00168	0.0	neu	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR repeat-like domain
HIGHFHGP_00169	5.05e-310	-	-	-	P	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HIGHFHGP_00170	2.69e-194	-	-	-	K	-	-	-	FCD
HIGHFHGP_00172	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HIGHFHGP_00173	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HIGHFHGP_00174	0.0	pbp5	-	-	M	-	-	-	Transglycosylase
HIGHFHGP_00175	1.03e-226	-	-	-	I	-	-	-	PAP2 superfamily
HIGHFHGP_00176	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIGHFHGP_00177	4.11e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIGHFHGP_00178	4.36e-264	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HIGHFHGP_00179	6.09e-136	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_00180	1.47e-50	hpr	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HIGHFHGP_00182	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIGHFHGP_00183	1.52e-137	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HIGHFHGP_00184	0.0	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HIGHFHGP_00185	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formate-tetrahydrofolate ligase
HIGHFHGP_00186	1.11e-81	-	-	-	S	-	-	-	Macrophage migration inhibitory factor (MIF)
HIGHFHGP_00187	1.29e-124	-	-	-	S	-	-	-	GtrA-like protein
HIGHFHGP_00188	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_00189	1.02e-157	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HIGHFHGP_00190	1e-204	-	-	-	-	-	-	-	-
HIGHFHGP_00191	1.08e-49	-	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HIGHFHGP_00192	1.02e-233	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HIGHFHGP_00194	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIGHFHGP_00197	4.56e-79	intA	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HIGHFHGP_00199	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	Iron permease FTR1 family
HIGHFHGP_00200	1.89e-159	-	-	-	P	ko:K07230	-	ko00000,ko02000	Fe2+ transport protein
HIGHFHGP_00201	8.65e-293	-	-	-	S	-	-	-	Predicted membrane protein (DUF2318)
HIGHFHGP_00202	7.36e-291	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HIGHFHGP_00203	3.29e-277	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIGHFHGP_00204	1.39e-187	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_00205	1.68e-102	-	-	-	S	-	-	-	FMN_bind
HIGHFHGP_00206	6.6e-130	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00207	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HIGHFHGP_00208	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HIGHFHGP_00209	0.0	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HIGHFHGP_00210	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIGHFHGP_00211	8.69e-194	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HIGHFHGP_00212	1.04e-247	opcA	-	-	G	-	-	-	Glucose-6-phosphate dehydrogenase subunit
HIGHFHGP_00213	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIGHFHGP_00214	0.0	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HIGHFHGP_00216	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
HIGHFHGP_00217	3.8e-252	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase like family 2
HIGHFHGP_00218	4.13e-193	icaR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_00219	1.45e-234	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIGHFHGP_00220	3.75e-303	amt	-	-	U	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
HIGHFHGP_00221	1.27e-72	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HIGHFHGP_00222	0.0	glnD	2.7.7.59	-	O	ko:K00990	ko02020,map02020	ko00000,ko00001,ko01000	Nucleotidyltransferase domain
HIGHFHGP_00223	7.04e-304	dinF	-	-	V	-	-	-	MatE
HIGHFHGP_00224	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HIGHFHGP_00225	0.0	murE	-	-	M	-	-	-	Domain of unknown function (DUF1727)
HIGHFHGP_00226	4.49e-181	cobQ2	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HIGHFHGP_00227	1.1e-51	-	-	-	S	-	-	-	granule-associated protein
HIGHFHGP_00228	0.0	-	-	-	S	ko:K03688	-	ko00000	ABC1 family
HIGHFHGP_00229	1.01e-89	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
HIGHFHGP_00230	1.27e-113	-	3.2.1.185	GH127	S	ko:K09955,ko:K18205	-	ko00000,ko01000	Beta-L-arabinofuranosidase, GH127
HIGHFHGP_00231	3.01e-197	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HIGHFHGP_00232	3.31e-238	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIGHFHGP_00233	2.77e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HIGHFHGP_00234	2.88e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HIGHFHGP_00235	2.15e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIGHFHGP_00236	4.72e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HIGHFHGP_00238	2.54e-161	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HIGHFHGP_00239	0.0	-	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	E1-E2 ATPase
HIGHFHGP_00240	1.64e-57	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	Metal-sensitive transcriptional repressor
HIGHFHGP_00241	1.26e-274	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HIGHFHGP_00242	9.81e-142	pyrE1	-	-	F	-	-	-	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIGHFHGP_00243	9.95e-216	trmH	2.1.1.34	-	J	ko:K00556	-	ko00000,ko01000,ko03016	RNA methyltransferase TrmH family
HIGHFHGP_00244	2.73e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HIGHFHGP_00245	4.41e-228	-	-	-	-	-	-	-	-
HIGHFHGP_00246	4.14e-69	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HIGHFHGP_00248	6.22e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIGHFHGP_00249	0.0	gatA	6.3.5.6, 6.3.5.7	-	F	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIGHFHGP_00250	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIGHFHGP_00251	5.57e-247	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_00252	2.66e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF2469)
HIGHFHGP_00253	0.0	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HIGHFHGP_00254	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HIGHFHGP_00255	1.19e-57	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
HIGHFHGP_00256	1.53e-56	-	-	-	L	ko:K07485	-	ko00000	Transposase
HIGHFHGP_00257	7.24e-64	-	-	-	L	ko:K07485	-	ko00000	Transposase
HIGHFHGP_00258	1.25e-44	-	-	-	K	-	-	-	AraC-like ligand binding domain
HIGHFHGP_00260	6.17e-191	araN	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00261	5.07e-159	-	-	-	P	ko:K10189,ko:K10241	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00262	3.11e-145	araQ	-	-	U	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00263	1.14e-155	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HIGHFHGP_00264	3.5e-46	-	-	-	L	-	-	-	Helix-turn-helix domain
HIGHFHGP_00265	4.7e-62	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Amino-transferase class IV
HIGHFHGP_00266	6.34e-81	tyrA	5.4.99.5	-	E	ko:K04092	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase type II
HIGHFHGP_00267	0.0	-	-	-	S	-	-	-	domain protein
HIGHFHGP_00268	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIGHFHGP_00269	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIGHFHGP_00270	6.93e-162	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIGHFHGP_00271	2.67e-179	glnR	-	-	KT	-	-	-	Transcriptional regulatory protein, C terminal
HIGHFHGP_00272	2.55e-154	-	-	-	-	-	-	-	-
HIGHFHGP_00273	2.74e-126	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HIGHFHGP_00274	1.95e-119	ppa	3.6.1.1	-	C	ko:K01507	ko00190,map00190	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HIGHFHGP_00275	0.0	glgE	2.4.99.16	GH13	G	ko:K16147	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HIGHFHGP_00276	0.0	-	-	-	K	-	-	-	RNA polymerase II activating transcription factor binding
HIGHFHGP_00278	4.83e-09	-	-	-	K	-	-	-	sequence-specific DNA binding
HIGHFHGP_00282	1.31e-23	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HIGHFHGP_00287	1.65e-67	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HIGHFHGP_00291	4.08e-44	-	-	-	V	-	-	-	HNH endonuclease
HIGHFHGP_00292	1.81e-53	-	-	-	A	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HIGHFHGP_00293	1.23e-53	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
HIGHFHGP_00297	1.86e-11	-	-	-	-	-	-	-	-
HIGHFHGP_00300	1.35e-11	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HIGHFHGP_00305	2.49e-46	-	-	-	L	-	-	-	HNH endonuclease
HIGHFHGP_00306	2.07e-11	-	-	-	-	-	-	-	-
HIGHFHGP_00307	6.96e-304	-	-	-	S	-	-	-	Terminase
HIGHFHGP_00308	7.26e-226	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HIGHFHGP_00309	1.82e-211	-	-	-	-	-	-	-	-
HIGHFHGP_00310	4.51e-54	-	-	-	-	-	-	-	-
HIGHFHGP_00311	2.32e-188	-	-	-	V	-	-	-	Phage capsid family
HIGHFHGP_00313	1.89e-60	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
HIGHFHGP_00314	1.08e-41	-	-	-	-	-	-	-	-
HIGHFHGP_00317	1.27e-77	-	-	-	N	-	-	-	domain, Protein
HIGHFHGP_00318	1.62e-36	-	-	-	-	-	-	-	-
HIGHFHGP_00320	2.72e-94	-	-	-	NT	-	-	-	phage tail tape measure protein
HIGHFHGP_00321	7.05e-69	-	-	-	S	-	-	-	phage tail
HIGHFHGP_00322	5.45e-282	-	-	-	S	-	-	-	Prophage endopeptidase tail
HIGHFHGP_00325	1.43e-46	-	-	-	-	-	-	-	-
HIGHFHGP_00326	8.36e-154	-	-	-	-	-	-	-	-
HIGHFHGP_00327	4.06e-105	-	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	reverse transcriptase
HIGHFHGP_00329	5.22e-23	-	-	-	-	-	-	-	-
HIGHFHGP_00330	8.39e-136	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HIGHFHGP_00331	3.56e-38	-	-	-	S	-	-	-	Putative phage holin Dp-1
HIGHFHGP_00332	7.04e-50	-	-	-	-	-	-	-	-
HIGHFHGP_00333	2.19e-56	-	-	-	S	ko:K09803	-	ko00000	Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
HIGHFHGP_00334	1.11e-127	-	-	-	L	-	-	-	Phage integrase family
HIGHFHGP_00336	3.5e-263	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIGHFHGP_00337	1.02e-191	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HIGHFHGP_00338	1.65e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIGHFHGP_00339	1.05e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIGHFHGP_00340	2.05e-191	atpH	-	-	C	ko:K02109,ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIGHFHGP_00341	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIGHFHGP_00342	3.59e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIGHFHGP_00343	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIGHFHGP_00344	3.62e-65	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HIGHFHGP_00345	3.01e-166	nucS	-	-	L	ko:K07503	-	ko00000,ko01000	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HIGHFHGP_00346	3.45e-214	-	5.2.1.8	-	M	ko:K01802	-	ko00000,ko01000	FKBP-type peptidyl-prolyl cis-trans isomerase
HIGHFHGP_00347	1e-247	-	-	-	-	-	-	-	-
HIGHFHGP_00348	9.39e-232	-	-	-	-	-	-	-	-
HIGHFHGP_00349	7.29e-219	ybbN	-	-	O	ko:K05838	-	ko00000,ko03110	Tetratricopeptide repeat
HIGHFHGP_00350	3.07e-149	-	-	-	S	-	-	-	CYTH
HIGHFHGP_00353	2.69e-82	psp1	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	Endoribonuclease L-PSP
HIGHFHGP_00354	7.25e-241	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HIGHFHGP_00355	1.38e-228	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HIGHFHGP_00356	1.73e-292	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HIGHFHGP_00357	2.14e-278	-	-	-	P	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00358	1.14e-205	-	-	-	U	ko:K02054	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00359	1.18e-198	-	-	-	U	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00360	1.12e-303	-	-	-	E	ko:K02052	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HIGHFHGP_00361	7.19e-237	-	-	-	S	-	-	-	CAAX protease self-immunity
HIGHFHGP_00362	1.31e-175	-	-	-	M	-	-	-	Mechanosensitive ion channel
HIGHFHGP_00363	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HIGHFHGP_00364	4.36e-16	-	-	-	L	-	-	-	Transposase DDE domain
HIGHFHGP_00365	1.41e-172	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HIGHFHGP_00366	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HIGHFHGP_00367	5.79e-247	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_00368	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HIGHFHGP_00369	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00370	1.85e-211	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00371	1.14e-227	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00372	3.17e-301	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HIGHFHGP_00373	1.28e-50	-	-	-	L	-	-	-	Transposase, Mutator family
HIGHFHGP_00374	2.01e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_00375	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00376	1.37e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIGHFHGP_00377	2.71e-107	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIGHFHGP_00378	1.65e-93	ams	2.4.1.4	GH13	G	ko:K05341	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HIGHFHGP_00379	9.55e-149	-	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HIGHFHGP_00381	1.84e-223	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HIGHFHGP_00382	5.31e-39	-	-	-	K	-	-	-	Transcriptional regulator
HIGHFHGP_00386	4.64e-112	-	-	-	K	-	-	-	Helix-turn-helix domain protein
HIGHFHGP_00389	6.48e-33	-	-	-	S	-	-	-	Putative phage holin Dp-1
HIGHFHGP_00390	6.3e-10	-	-	-	-	-	-	-	-
HIGHFHGP_00391	1.74e-103	-	-	-	-	-	-	-	-
HIGHFHGP_00392	0.0	-	-	-	M	-	-	-	Conserved repeat domain
HIGHFHGP_00393	0.0	-	-	-	M	-	-	-	LPXTG cell wall anchor motif
HIGHFHGP_00395	1.08e-66	-	-	-	-	-	-	-	-
HIGHFHGP_00396	3.86e-16	-	-	-	-	-	-	-	-
HIGHFHGP_00397	2.26e-145	-	-	-	-	-	-	-	-
HIGHFHGP_00398	2.04e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIGHFHGP_00399	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HIGHFHGP_00400	1.01e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HIGHFHGP_00401	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HIGHFHGP_00403	3.58e-32	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HIGHFHGP_00404	5e-102	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HIGHFHGP_00405	4.59e-130	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HIGHFHGP_00406	1.42e-28	-	-	-	-	-	-	-	-
HIGHFHGP_00407	9.62e-215	-	-	-	C	-	-	-	Oxidoreductase, aldo keto reductase family protein
HIGHFHGP_00408	1.83e-258	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HIGHFHGP_00409	5.15e-138	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIGHFHGP_00410	3.56e-47	-	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HIGHFHGP_00411	1.05e-82	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HIGHFHGP_00412	1.33e-270	-	-	-	S	-	-	-	Endonuclease/Exonuclease/phosphatase family
HIGHFHGP_00413	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIGHFHGP_00414	3.05e-205	-	-	-	P	-	-	-	Cation efflux family
HIGHFHGP_00415	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HIGHFHGP_00416	2.75e-174	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase C26
HIGHFHGP_00417	0.0	yjjK	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter
HIGHFHGP_00418	9.42e-95	vapC	-	-	S	ko:K07062	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module. An RNase
HIGHFHGP_00419	1.52e-57	-	-	-	S	ko:K21495	-	ko00000,ko02048	Plasmid stability protein
HIGHFHGP_00420	8.22e-120	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ACT domain
HIGHFHGP_00421	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
HIGHFHGP_00422	6.09e-173	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIGHFHGP_00423	4.87e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HIGHFHGP_00424	5.31e-149	-	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HIGHFHGP_00425	1.34e-151	-	-	-	-	-	-	-	-
HIGHFHGP_00426	9.97e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIGHFHGP_00427	1.08e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3039)
HIGHFHGP_00428	7.32e-235	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
HIGHFHGP_00429	4.04e-132	-	-	-	S	-	-	-	Carbon-nitrogen hydrolase
HIGHFHGP_00430	7.97e-148	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
HIGHFHGP_00431	1.07e-110	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HIGHFHGP_00432	9.1e-179	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
HIGHFHGP_00433	1.33e-269	-	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
HIGHFHGP_00434	5.1e-165	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
HIGHFHGP_00435	3.94e-250	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
HIGHFHGP_00436	7.41e-102	-	-	-	K	-	-	-	MerR, DNA binding
HIGHFHGP_00437	5.52e-152	-	-	-	-	-	-	-	-
HIGHFHGP_00438	1.89e-316	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIGHFHGP_00439	3.84e-186	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HIGHFHGP_00440	8.53e-171	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIGHFHGP_00441	7.64e-226	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HIGHFHGP_00444	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HIGHFHGP_00445	0.0	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00446	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00447	4.28e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIGHFHGP_00448	2.39e-225	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HIGHFHGP_00449	1.16e-205	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIGHFHGP_00450	6.04e-270	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_00451	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HIGHFHGP_00452	7.17e-47	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HIGHFHGP_00453	3.25e-29	-	-	-	U	ko:K02100	-	ko00000,ko02000	Sugar (and other) transporter
HIGHFHGP_00455	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter transmembrane region
HIGHFHGP_00456	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00457	3.53e-129	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00458	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00459	6.75e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_00460	0.0	galA	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	Glycosyl hydrolase family 53
HIGHFHGP_00461	9.94e-209	-	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HIGHFHGP_00462	8.69e-180	-	-	-	L	-	-	-	Protein of unknown function (DUF1524)
HIGHFHGP_00463	6.79e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4143)
HIGHFHGP_00464	7.84e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HIGHFHGP_00465	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HIGHFHGP_00466	0.0	-	-	-	H	-	-	-	Protein of unknown function (DUF4012)
HIGHFHGP_00467	0.0	rfbP	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HIGHFHGP_00468	1.78e-140	etp	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Low molecular weight phosphatase family
HIGHFHGP_00469	1.61e-47	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HIGHFHGP_00470	5.57e-308	-	-	-	K	-	-	-	Putative DNA-binding domain
HIGHFHGP_00471	2.8e-171	-	-	-	L	-	-	-	PFAM Integrase catalytic
HIGHFHGP_00472	3.48e-230	tnp7109-2	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
HIGHFHGP_00473	1.3e-112	-	-	-	L	-	-	-	HTH-like domain
HIGHFHGP_00474	8.06e-36	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HIGHFHGP_00475	5.99e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIGHFHGP_00476	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIGHFHGP_00477	6.43e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIGHFHGP_00478	2.29e-64	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00479	8.35e-44	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00480	9.57e-44	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00481	2.92e-63	tnpA	-	-	L	-	-	-	Transposase
HIGHFHGP_00482	7.12e-27	tnpA	-	-	L	-	-	-	Transposase
HIGHFHGP_00483	1.22e-130	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HIGHFHGP_00484	8.19e-55	-	-	-	M	-	-	-	group 2 family protein
HIGHFHGP_00487	1.01e-29	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HIGHFHGP_00488	2.81e-93	-	-	-	S	-	-	-	polysaccharide biosynthetic process
HIGHFHGP_00489	2e-12	-	-	-	L	-	-	-	Transposase, Mutator family
HIGHFHGP_00490	4.46e-277	-	-	-	L	ko:K07485	-	ko00000	Transposase
HIGHFHGP_00491	1.34e-54	-	-	-	L	-	-	-	Transposase, Mutator family
HIGHFHGP_00492	5.25e-47	-	-	-	L	-	-	-	Transposase, Mutator family
HIGHFHGP_00493	1.76e-213	-	-	-	L	-	-	-	Transposase
HIGHFHGP_00494	2.4e-87	-	-	-	L	-	-	-	IstB-like ATP binding protein
HIGHFHGP_00495	1.91e-77	-	-	-	G	-	-	-	Acyltransferase family
HIGHFHGP_00496	5.21e-22	-	-	-	G	-	-	-	Acyltransferase family
HIGHFHGP_00497	6.54e-07	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HIGHFHGP_00498	1.61e-64	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00499	2.04e-57	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00500	4.95e-45	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00501	1.03e-16	-	-	-	L	-	-	-	transposase activity
HIGHFHGP_00502	4.9e-152	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HIGHFHGP_00503	1.4e-273	-	-	-	L	-	-	-	PFAM Integrase catalytic
HIGHFHGP_00504	3.34e-48	-	-	-	L	-	-	-	Transposase
HIGHFHGP_00505	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HIGHFHGP_00506	9.65e-90	-	-	-	-	-	-	-	-
HIGHFHGP_00507	4.11e-310	wcoI	-	-	DM	-	-	-	Psort location CytoplasmicMembrane, score
HIGHFHGP_00508	3.94e-231	-	-	-	-	-	-	-	-
HIGHFHGP_00509	3.98e-186	-	-	-	S	ko:K21688	-	ko00000	G5
HIGHFHGP_00510	5.55e-79	trxA	1.8.1.9	-	O	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	ko00000,ko00001,ko01000,ko03110	Belongs to the thioredoxin family
HIGHFHGP_00511	7.47e-156	-	-	-	F	-	-	-	Domain of unknown function (DUF4916)
HIGHFHGP_00512	1.41e-204	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HIGHFHGP_00513	1.2e-281	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HIGHFHGP_00514	1.26e-91	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HIGHFHGP_00515	4.05e-284	-	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2183)
HIGHFHGP_00516	0.0	ptrB	3.4.21.83	-	E	ko:K01354	ko05142,ko05143,map05142,map05143	ko00000,ko00001,ko01000,ko01002	Peptidase, S9A B C family, catalytic domain protein
HIGHFHGP_00517	8.89e-246	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HIGHFHGP_00518	2.37e-279	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Biotin/lipoate A/B protein ligase family
HIGHFHGP_00519	2.7e-172	crp	-	-	K	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HIGHFHGP_00520	0.0	pon1	-	-	M	-	-	-	Transglycosylase
HIGHFHGP_00521	4.95e-305	namA	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
HIGHFHGP_00522	1.25e-288	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HIGHFHGP_00523	3.61e-158	-	-	-	K	-	-	-	DeoR C terminal sensor domain
HIGHFHGP_00524	0.0	galT	2.7.7.12	-	C	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	Galactose-1-phosphate uridyl transferase, N-terminal domain
HIGHFHGP_00525	6.15e-299	galK	2.7.1.6, 2.7.7.12	-	G	ko:K00849,ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HIGHFHGP_00526	7.93e-59	-	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HIGHFHGP_00527	0.0	-	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HIGHFHGP_00528	3.37e-148	spoU	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIGHFHGP_00529	1.46e-237	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	FES
HIGHFHGP_00530	5.49e-131	-	-	-	-	-	-	-	-
HIGHFHGP_00531	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIGHFHGP_00532	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIGHFHGP_00533	0.0	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HIGHFHGP_00534	5.35e-307	-	-	-	S	-	-	-	Protein of unknown function DUF58
HIGHFHGP_00535	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HIGHFHGP_00536	5.92e-282	pknK	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HIGHFHGP_00537	0.0	-	-	-	L	-	-	-	PD-(D/E)XK nuclease superfamily
HIGHFHGP_00538	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HIGHFHGP_00539	9.52e-301	-	-	-	G	-	-	-	Major Facilitator Superfamily
HIGHFHGP_00540	2.38e-172	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIGHFHGP_00541	2.06e-208	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIGHFHGP_00542	0.0	rnj	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIGHFHGP_00543	0.0	pepN	3.4.11.2	-	E	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HIGHFHGP_00544	3.74e-63	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HIGHFHGP_00546	1.35e-130	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00547	2.49e-137	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00548	7.43e-149	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00549	1.33e-162	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HIGHFHGP_00550	5.35e-30	-	-	-	K	-	-	-	AraC-like ligand binding domain
HIGHFHGP_00551	4.46e-50	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HIGHFHGP_00552	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIGHFHGP_00553	3.06e-158	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIGHFHGP_00554	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HIGHFHGP_00555	2.52e-263	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIGHFHGP_00556	7.25e-266	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Cell division ATP-binding protein FtsE
HIGHFHGP_00557	1.9e-206	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in cellular division
HIGHFHGP_00558	6.04e-204	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain protein
HIGHFHGP_00559	1.14e-106	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HIGHFHGP_00560	1.21e-198	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HIGHFHGP_00561	2.17e-215	glnH	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter, substrate-binding protein, family 3
HIGHFHGP_00562	4.05e-220	yecS	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00563	1.83e-193	tcyC	3.6.3.21	-	E	ko:K02028,ko:K02029	-	ko00000,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00564	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIGHFHGP_00565	4.18e-179	-	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	RNA pseudouridylate synthase
HIGHFHGP_00566	8.78e-238	-	-	-	K	-	-	-	Periplasmic binding protein domain
HIGHFHGP_00567	2.55e-216	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00568	2.47e-226	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HIGHFHGP_00569	0.0	bga1	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00570	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00571	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00572	2.22e-184	coaX	2.7.1.33	-	H	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HIGHFHGP_00573	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HIGHFHGP_00574	1.35e-215	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00575	2.97e-193	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00576	7.6e-175	-	-	-	EP	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	oligopeptide transport protein of the ABC superfamily, ATP-binding component
HIGHFHGP_00577	2.77e-176	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00578	1.73e-246	cbs	2.5.1.47, 4.2.1.22	-	E	ko:K01697,ko:K01738	ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HIGHFHGP_00579	5.91e-279	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HIGHFHGP_00580	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HIGHFHGP_00581	2.77e-119	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIGHFHGP_00582	7.45e-134	cysE	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HIGHFHGP_00583	0.0	aap1	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HIGHFHGP_00584	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIGHFHGP_00585	1.19e-309	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Phosphohydrolase-associated domain
HIGHFHGP_00586	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIGHFHGP_00587	2.7e-198	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HIGHFHGP_00588	1.4e-147	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HIGHFHGP_00589	0.0	-	-	-	EK	ko:K03710,ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000,ko03000	Alanine-glyoxylate amino-transferase
HIGHFHGP_00590	1.36e-267	-	-	-	P	-	-	-	Citrate transporter
HIGHFHGP_00591	9.8e-41	-	-	-	-	-	-	-	-
HIGHFHGP_00592	8.43e-51	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HIGHFHGP_00593	1.11e-205	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HIGHFHGP_00596	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00597	2.79e-294	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_00598	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HIGHFHGP_00599	1.98e-18	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00600	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HIGHFHGP_00601	2.56e-110	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	peptide-methionine (S)-S-oxide reductase activity
HIGHFHGP_00602	9.32e-184	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00603	6.39e-249	-	-	-	M	-	-	-	Conserved repeat domain
HIGHFHGP_00604	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HIGHFHGP_00605	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIGHFHGP_00606	3.27e-230	yogA	-	-	C	-	-	-	Zinc-binding dehydrogenase
HIGHFHGP_00607	4.18e-111	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIGHFHGP_00608	4.92e-286	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIGHFHGP_00609	7.7e-95	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HIGHFHGP_00610	4.41e-98	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIGHFHGP_00611	4.47e-33	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIGHFHGP_00612	4.25e-91	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HIGHFHGP_00613	9.84e-85	-	-	-	-	-	-	-	-
HIGHFHGP_00614	5.67e-73	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
HIGHFHGP_00615	2.84e-27	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Ferric uptake regulator family
HIGHFHGP_00616	1.14e-179	-	-	-	S	-	-	-	TIGRFAM TIGR03943 family protein
HIGHFHGP_00617	4.63e-255	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HIGHFHGP_00619	3.79e-05	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
HIGHFHGP_00620	2.42e-209	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HIGHFHGP_00621	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HIGHFHGP_00622	0.0	aldH	1.2.1.3, 1.2.99.10	-	C	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldehyde dehydrogenase family
HIGHFHGP_00623	1e-307	purD	6.3.3.1, 6.3.4.13	-	F	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HIGHFHGP_00624	1.84e-239	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HIGHFHGP_00625	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIGHFHGP_00626	0.0	-	-	-	L	ko:K03502	-	ko00000,ko03400	DNA-damage repair protein (DNA polymerase IV) K00961
HIGHFHGP_00627	1.4e-44	-	-	-	-	-	-	-	-
HIGHFHGP_00628	2.77e-17	-	-	-	C	-	-	-	Aldo/keto reductase family
HIGHFHGP_00629	2.67e-132	nnrE	-	-	L	-	-	-	Uracil DNA glycosylase superfamily
HIGHFHGP_00633	8.33e-187	-	-	-	-	-	-	-	-
HIGHFHGP_00634	3.12e-143	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HIGHFHGP_00635	0.0	-	-	-	Q	-	-	-	D-alanine [D-alanyl carrier protein] ligase activity
HIGHFHGP_00636	9.37e-311	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HIGHFHGP_00637	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	CobB/CobQ-like glutamine amidotransferase domain
HIGHFHGP_00638	4.83e-176	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HIGHFHGP_00639	3.02e-294	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HIGHFHGP_00640	1.27e-291	-	2.6.1.1, 2.6.1.2, 2.6.1.66, 2.6.1.83	-	E	ko:K00812,ko:K08969,ko:K10206,ko:K14260,ko:K14261	ko00220,ko00250,ko00270,ko00290,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HIGHFHGP_00641	9.06e-279	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HIGHFHGP_00642	2.12e-252	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Beta-eliminating lyase
HIGHFHGP_00644	1.94e-247	-	-	-	S	ko:K03453	-	ko00000	SBF-like CPA transporter family (DUF4137)
HIGHFHGP_00645	5.77e-81	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIGHFHGP_00646	1.9e-104	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIGHFHGP_00647	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIGHFHGP_00648	4.1e-293	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIGHFHGP_00649	2.99e-164	tmp1	-	-	S	-	-	-	Domain of unknown function (DUF4391)
HIGHFHGP_00650	9e-187	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HIGHFHGP_00651	1.24e-237	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HIGHFHGP_00653	3.11e-28	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HIGHFHGP_00654	2.28e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIGHFHGP_00655	3.01e-114	-	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIGHFHGP_00656	1.57e-87	-	-	-	K	-	-	-	MerR family regulatory protein
HIGHFHGP_00657	1.27e-247	adh	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HIGHFHGP_00658	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HIGHFHGP_00659	4.18e-141	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HIGHFHGP_00660	2.56e-216	-	-	-	C	-	-	-	Domain of unknown function
HIGHFHGP_00661	8.55e-305	-	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_00662	5.39e-182	-	-	-	G	ko:K02026,ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00663	1.58e-217	-	-	-	P	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00664	1.5e-206	-	-	-	P	-	-	-	Phosphate transporter family
HIGHFHGP_00665	1.12e-243	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_00666	5.16e-15	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HIGHFHGP_00667	7.53e-26	-	-	-	L	-	-	-	transposase activity
HIGHFHGP_00668	1.49e-18	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00669	5.39e-43	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00670	5.09e-149	-	-	-	F	-	-	-	Permease family
HIGHFHGP_00671	3.45e-218	guaD	3.5.4.28, 3.5.4.3, 3.5.4.31	-	F	ko:K01487,ko:K12960	ko00230,ko00270,ko01100,map00230,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HIGHFHGP_00672	2.42e-14	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HIGHFHGP_00673	5.39e-43	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00674	1.49e-18	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00675	1.31e-113	-	-	-	L	-	-	-	PFAM Integrase catalytic
HIGHFHGP_00676	5.14e-23	-	-	-	S	-	-	-	AIPR protein
HIGHFHGP_00677	6.17e-186	-	-	-	K	-	-	-	LysR substrate binding domain
HIGHFHGP_00678	5.6e-130	-	-	-	K	-	-	-	LysR substrate binding domain
HIGHFHGP_00679	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HIGHFHGP_00680	8.03e-311	-	-	-	V	-	-	-	MatE
HIGHFHGP_00681	3.8e-160	-	-	-	L	ko:K07457	-	ko00000	endonuclease III
HIGHFHGP_00682	0.000168	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HIGHFHGP_00683	1.55e-152	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HIGHFHGP_00684	1.68e-53	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HIGHFHGP_00685	8.37e-237	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HIGHFHGP_00686	6.16e-111	-	-	-	L	-	-	-	Transposase
HIGHFHGP_00687	6.31e-24	-	-	-	-	-	-	-	-
HIGHFHGP_00688	6.47e-37	-	-	-	-	-	-	-	-
HIGHFHGP_00689	1.36e-17	-	-	-	-	-	-	-	-
HIGHFHGP_00690	2.4e-107	-	-	-	M	-	-	-	L,D-transpeptidase catalytic domain
HIGHFHGP_00691	1.03e-167	-	-	-	V	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HIGHFHGP_00692	1.18e-160	-	-	-	V	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00693	6.57e-136	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIGHFHGP_00694	9.79e-119	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIGHFHGP_00695	6.96e-305	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HIGHFHGP_00696	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HIGHFHGP_00697	2.65e-217	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HIGHFHGP_00698	9.2e-136	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HIGHFHGP_00699	2.06e-174	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Exonuclease, DNA polymerase III, epsilon subunit family
HIGHFHGP_00701	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
HIGHFHGP_00702	1.27e-25	-	-	-	S	-	-	-	Putative phage holin Dp-1
HIGHFHGP_00703	9.18e-109	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HIGHFHGP_00708	3.03e-45	-	-	-	-	-	-	-	-
HIGHFHGP_00710	3.88e-216	-	-	-	S	-	-	-	cellulase activity
HIGHFHGP_00712	5.13e-115	-	-	-	NT	-	-	-	phage tail tape measure protein
HIGHFHGP_00715	1.24e-81	-	-	-	N	-	-	-	domain, Protein
HIGHFHGP_00716	4.68e-49	-	-	-	-	-	-	-	-
HIGHFHGP_00717	5.55e-28	-	-	-	-	-	-	-	-
HIGHFHGP_00718	1.39e-59	-	-	-	-	-	-	-	-
HIGHFHGP_00719	2.1e-56	-	-	-	S	-	-	-	Phage protein Gp19/Gp15/Gp42
HIGHFHGP_00720	2.52e-76	-	-	-	-	-	-	-	-
HIGHFHGP_00721	7.77e-209	-	-	-	S	-	-	-	Phage capsid family
HIGHFHGP_00722	2.14e-60	-	-	-	-	-	-	-	-
HIGHFHGP_00724	1.44e-69	-	-	-	-	-	-	-	-
HIGHFHGP_00725	8.58e-223	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HIGHFHGP_00726	3.67e-227	-	-	-	S	-	-	-	Terminase
HIGHFHGP_00727	9.94e-40	-	-	-	-	-	-	-	-
HIGHFHGP_00728	3.6e-36	-	-	-	L	-	-	-	HNH endonuclease
HIGHFHGP_00733	1.1e-90	-	-	-	-	-	-	-	-
HIGHFHGP_00743	7.1e-66	-	-	-	V	-	-	-	HNH endonuclease
HIGHFHGP_00745	8.63e-69	-	-	-	K	-	-	-	Transcriptional regulator
HIGHFHGP_00747	3.89e-106	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HIGHFHGP_00748	1.86e-65	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HIGHFHGP_00756	7e-33	-	-	-	-	-	-	-	-
HIGHFHGP_00757	1.24e-31	-	-	-	-	-	-	-	-
HIGHFHGP_00758	3.09e-220	-	-	-	S	ko:K07504	-	ko00000	Type I restriction enzyme R protein N terminus (HSDR_N)
HIGHFHGP_00759	4.14e-87	-	-	-	S	-	-	-	P63C domain
HIGHFHGP_00760	6.65e-146	-	-	-	L	-	-	-	Phage integrase family
HIGHFHGP_00761	2.07e-161	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HIGHFHGP_00762	7.76e-299	metC1	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HIGHFHGP_00763	1.32e-56	-	-	-	O	-	-	-	Glutaredoxin
HIGHFHGP_00764	1.41e-11	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Cys/Met metabolism PLP-dependent enzyme
HIGHFHGP_00765	1.79e-170	hflK	-	-	O	-	-	-	prohibitin homologues
HIGHFHGP_00766	1.1e-70	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HIGHFHGP_00767	5.74e-204	-	-	-	S	-	-	-	Patatin-like phospholipase
HIGHFHGP_00768	5.69e-191	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HIGHFHGP_00769	3.24e-219	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HIGHFHGP_00770	5.62e-165	-	-	-	S	-	-	-	Vitamin K epoxide reductase
HIGHFHGP_00771	1.08e-216	PPA1328	3.1.3.97, 3.1.4.57	-	S	ko:K07053,ko:K20859	ko00440,map00440	ko00000,ko00001,ko01000	DNA polymerase alpha chain like domain
HIGHFHGP_00772	2.77e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF3107)
HIGHFHGP_00773	0.0	mphA	-	-	S	-	-	-	Aminoglycoside phosphotransferase
HIGHFHGP_00774	0.0	uvrD2	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HIGHFHGP_00775	0.0	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HIGHFHGP_00776	2.47e-209	sdrC	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HIGHFHGP_00777	2.42e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3052)
HIGHFHGP_00779	3.93e-301	-	-	-	NU	-	-	-	Tfp pilus assembly protein FimV
HIGHFHGP_00780	2.07e-280	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HIGHFHGP_00781	6.58e-294	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HIGHFHGP_00782	0.0	-	-	-	I	-	-	-	acetylesterase activity
HIGHFHGP_00783	6.84e-166	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HIGHFHGP_00784	1.58e-197	uppS	2.5.1.31, 2.5.1.86, 2.5.1.88	-	H	ko:K00806,ko:K14215,ko:K21273	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIGHFHGP_00785	2.46e-173	-	-	-	P	-	-	-	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00786	5.32e-244	-	-	-	P	-	-	-	NMT1/THI5 like
HIGHFHGP_00787	4.23e-288	-	-	-	E	-	-	-	Aminotransferase class I and II
HIGHFHGP_00788	3.25e-181	-	-	-	P	ko:K16784	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00790	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIGHFHGP_00791	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HIGHFHGP_00792	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIGHFHGP_00793	2.72e-262	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HIGHFHGP_00794	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HIGHFHGP_00795	1.18e-181	-	-	-	S	-	-	-	Domain of unknown function (DUF4191)
HIGHFHGP_00796	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HIGHFHGP_00797	4.43e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3043)
HIGHFHGP_00798	0.0	argE	-	-	E	-	-	-	Peptidase dimerisation domain
HIGHFHGP_00799	4.38e-140	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HIGHFHGP_00800	0.0	ykoD	-	-	P	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00801	4.34e-210	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HIGHFHGP_00803	1.64e-204	tsnR	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIGHFHGP_00804	4.35e-258	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIGHFHGP_00805	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Phenylalanyl-tRNA synthetase beta
HIGHFHGP_00806	1.79e-137	-	-	-	-	-	-	-	-
HIGHFHGP_00807	5.47e-258	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HIGHFHGP_00808	9.67e-272	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HIGHFHGP_00809	2.39e-226	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HIGHFHGP_00810	5.79e-316	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HIGHFHGP_00811	7.19e-234	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIGHFHGP_00812	1.24e-109	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HIGHFHGP_00813	1.2e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HIGHFHGP_00814	1.38e-76	-	-	-	L	-	-	-	PFAM Integrase catalytic
HIGHFHGP_00816	1.72e-58	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HIGHFHGP_00817	1.62e-44	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIGHFHGP_00818	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HIGHFHGP_00819	3.55e-39	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
HIGHFHGP_00820	1.02e-201	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HIGHFHGP_00821	3.41e-190	thiF	2.7.7.73, 2.7.7.80, 2.8.1.11	-	H	ko:K03148,ko:K21147	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	ThiF family
HIGHFHGP_00822	6.08e-93	-	-	-	P	-	-	-	Rhodanese Homology Domain
HIGHFHGP_00823	2.82e-132	-	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HIGHFHGP_00824	2.58e-180	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HIGHFHGP_00825	7.28e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HIGHFHGP_00826	0.0	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIGHFHGP_00827	4.25e-292	-	-	-	L	-	-	-	Tetratricopeptide repeat
HIGHFHGP_00828	2.4e-257	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
HIGHFHGP_00830	1.49e-178	tlyA	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HIGHFHGP_00831	1.89e-151	-	-	-	-	-	-	-	-
HIGHFHGP_00832	1.25e-64	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	TrkA-N domain
HIGHFHGP_00833	4.29e-50	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HIGHFHGP_00834	1.11e-235	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIGHFHGP_00835	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HIGHFHGP_00836	1.51e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HIGHFHGP_00837	9.74e-18	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_00838	2.96e-25	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_00839	3.46e-78	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HIGHFHGP_00840	1.27e-220	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00841	2.75e-155	-	-	-	S	-	-	-	ABC-2 family transporter protein
HIGHFHGP_00842	1.21e-126	-	-	-	S	-	-	-	ABC-2 family transporter protein
HIGHFHGP_00843	8.48e-09	-	-	-	S	-	-	-	Transposon-encoded protein TnpV
HIGHFHGP_00844	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase N terminus
HIGHFHGP_00845	1.06e-296	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HIGHFHGP_00846	1.26e-124	-	-	-	-	-	-	-	-
HIGHFHGP_00847	1.1e-177	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIGHFHGP_00848	2.08e-115	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HIGHFHGP_00849	1.19e-21	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HIGHFHGP_00850	0.0	-	-	-	S	ko:K09118	-	ko00000	Uncharacterised protein family (UPF0182)
HIGHFHGP_00851	6.7e-121	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HIGHFHGP_00852	5.77e-145	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIGHFHGP_00853	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIGHFHGP_00854	1.28e-227	-	-	-	C	-	-	-	Aldo/keto reductase family
HIGHFHGP_00855	2.49e-313	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIGHFHGP_00856	1.89e-113	-	-	-	D	-	-	-	Septum formation initiator
HIGHFHGP_00857	1.13e-132	-	-	-	S	ko:K09009	-	ko00000	Protein of unknown function (DUF501)
HIGHFHGP_00858	3.69e-233	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HIGHFHGP_00860	8.17e-122	-	-	-	-	-	-	-	-
HIGHFHGP_00861	0.0	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase alpha chain
HIGHFHGP_00862	8.17e-98	fkbP	5.2.1.8	-	G	ko:K01802	-	ko00000,ko01000	Peptidyl-prolyl cis-trans
HIGHFHGP_00863	7.1e-106	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIGHFHGP_00864	1.52e-195	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	Haemolysin-III related
HIGHFHGP_00865	0.0	pdtaS	2.7.13.3	-	T	ko:K00936	-	ko00000,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HIGHFHGP_00866	8.13e-62	whiB	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HIGHFHGP_00867	0.0	-	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK/SpoIIIE family
HIGHFHGP_00868	3.53e-294	lytR2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HIGHFHGP_00869	2.06e-74	whiB2	-	-	K	ko:K18955	-	ko00000,ko03000	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HIGHFHGP_00870	0.0	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HIGHFHGP_00871	0.0	-	-	-	-	-	-	-	-
HIGHFHGP_00872	2.13e-101	-	-	-	S	-	-	-	Zincin-like metallopeptidase
HIGHFHGP_00873	1.69e-189	-	-	-	T	-	-	-	Eukaryotic phosphomannomutase
HIGHFHGP_00874	9.12e-159	pyrE_1	-	-	S	-	-	-	Phosphoribosyl transferase domain
HIGHFHGP_00875	1.43e-249	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HIGHFHGP_00876	2.03e-163	cseB	-	-	T	-	-	-	Response regulator receiver domain protein
HIGHFHGP_00877	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HIGHFHGP_00878	2.16e-130	carD	-	-	K	ko:K07736	-	ko00000,ko03000	CarD-like/TRCF domain
HIGHFHGP_00879	2.52e-114	ispF	2.7.7.60, 4.6.1.12	-	H	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HIGHFHGP_00880	1.91e-175	znuB	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HIGHFHGP_00881	1.29e-206	-	-	-	P	ko:K02074	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_00882	5.3e-264	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Zinc-uptake complex component A periplasmic
HIGHFHGP_00883	1.53e-209	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIGHFHGP_00884	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HIGHFHGP_00885	3.02e-137	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIGHFHGP_00886	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIGHFHGP_00887	2.2e-227	terC	-	-	P	ko:K05794	-	ko00000	Integral membrane protein, TerC family
HIGHFHGP_00888	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HIGHFHGP_00889	6.02e-143	aspA	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HIGHFHGP_00891	2.41e-166	pdtaR	-	-	T	ko:K22010	-	ko00000,ko00002,ko02022	Response regulator receiver domain protein
HIGHFHGP_00892	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIGHFHGP_00893	4.64e-227	-	-	-	L	-	-	-	NIF3 (NGG1p interacting factor 3)
HIGHFHGP_00894	4e-162	-	-	-	L	-	-	-	NUDIX domain
HIGHFHGP_00895	0.0	glgX	3.2.1.68	CBM48,GH13	G	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HIGHFHGP_00896	3.93e-37	zntR	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HIGHFHGP_00897	3.52e-116	-	-	-	K	-	-	-	Putative zinc ribbon domain
HIGHFHGP_00898	4.36e-162	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HIGHFHGP_00900	2.25e-28	-	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HIGHFHGP_00902	1.75e-154	-	-	-	-	-	-	-	-
HIGHFHGP_00903	3.26e-274	-	-	-	-	-	-	-	-
HIGHFHGP_00904	0.0	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HIGHFHGP_00905	4.64e-295	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIGHFHGP_00906	0.0	pta	2.3.1.8	-	C	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphate acetyltransferase
HIGHFHGP_00908	1.37e-244	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIGHFHGP_00909	0.0	yrhL	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HIGHFHGP_00913	0.0	-	-	-	V	-	-	-	T5orf172
HIGHFHGP_00914	3.92e-23	-	-	-	-	-	-	-	-
HIGHFHGP_00915	4.4e-52	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00916	5.52e-74	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00917	2.42e-125	-	-	-	-	-	-	-	-
HIGHFHGP_00918	2.98e-127	-	-	-	-	-	-	-	-
HIGHFHGP_00919	4.79e-123	-	-	-	-	-	-	-	-
HIGHFHGP_00920	2.01e-102	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HIGHFHGP_00921	1.91e-09	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIGHFHGP_00922	6.36e-63	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIGHFHGP_00923	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HIGHFHGP_00924	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HIGHFHGP_00925	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIGHFHGP_00926	5.45e-86	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIGHFHGP_00927	7.2e-174	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HIGHFHGP_00930	5.46e-199	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIGHFHGP_00931	4.96e-223	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
HIGHFHGP_00932	4.01e-280	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIGHFHGP_00933	3.9e-146	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00934	2.31e-284	-	-	-	S	-	-	-	Peptidase dimerisation domain
HIGHFHGP_00935	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HIGHFHGP_00936	6.14e-52	-	-	-	-	-	-	-	-
HIGHFHGP_00937	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HIGHFHGP_00938	5.19e-222	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIGHFHGP_00939	6.98e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF3000)
HIGHFHGP_00940	0.0	rnd	3.1.13.5	-	J	ko:K03684	-	ko00000,ko01000,ko03016	3'-5' exonuclease
HIGHFHGP_00941	9.93e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIGHFHGP_00942	8.72e-313	-	-	-	P	ko:K03281	-	ko00000	Voltage gated chloride channel
HIGHFHGP_00943	4.53e-79	-	-	-	-	-	-	-	-
HIGHFHGP_00944	2.96e-151	clpP1	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIGHFHGP_00945	5.21e-155	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIGHFHGP_00946	0.0	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIGHFHGP_00949	1.07e-305	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HIGHFHGP_00950	5.59e-307	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HIGHFHGP_00951	3.22e-215	fmt2	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HIGHFHGP_00952	3.95e-147	safC	-	-	S	-	-	-	O-methyltransferase
HIGHFHGP_00953	4e-233	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HIGHFHGP_00954	0.0	sdhA	1.3.5.1, 1.3.5.4, 1.4.3.16	-	C	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	Succinate dehydrogenase flavoprotein subunit
HIGHFHGP_00955	0.0	dprA	-	-	LU	ko:K04096	-	ko00000	DNA recombination-mediator protein A
HIGHFHGP_00956	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI C-terminal
HIGHFHGP_00957	5.93e-97	yraN	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HIGHFHGP_00958	1.7e-27	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HIGHFHGP_00959	9.2e-210	pdxY	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HIGHFHGP_00960	0.0	-	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Aminotransferase class-V
HIGHFHGP_00961	4.4e-217	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_00962	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HIGHFHGP_00963	5.85e-170	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HIGHFHGP_00964	0.0	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_00965	0.0	pip	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	alpha/beta hydrolase fold
HIGHFHGP_00966	1.33e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIGHFHGP_00967	3.42e-199	glnH	-	-	ET	ko:K02030,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HIGHFHGP_00968	6.4e-176	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ATP binding protein of ABC transporter for glutamate aspartate K02028
HIGHFHGP_00969	2.26e-153	glnP	-	-	E	ko:K02029,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00970	6.51e-141	glnP2	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_00971	1.25e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIGHFHGP_00972	1.87e-310	-	-	-	S	-	-	-	HipA-like C-terminal domain
HIGHFHGP_00973	2.57e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2442)
HIGHFHGP_00974	1.33e-276	-	-	-	G	-	-	-	Transmembrane secretion effector
HIGHFHGP_00975	8.55e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_00976	7.74e-17	-	-	-	-	-	-	-	-
HIGHFHGP_00977	0.0	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HIGHFHGP_00978	1.45e-17	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HIGHFHGP_00979	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HIGHFHGP_00980	1.53e-307	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HIGHFHGP_00981	6.11e-189	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIGHFHGP_00982	1.73e-222	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIGHFHGP_00983	6.16e-281	-	-	-	GK	-	-	-	ROK family
HIGHFHGP_00984	1.41e-203	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HIGHFHGP_00985	0.0	gtr	-	-	U	ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Sugar (and other) transporter
HIGHFHGP_00986	0.0	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HIGHFHGP_00987	0.0	-	-	-	C	ko:K06871	-	ko00000	Iron-sulfur cluster-binding domain
HIGHFHGP_00988	2.15e-155	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HIGHFHGP_00989	5.31e-70	-	-	-	L	-	-	-	Helix-turn-helix domain
HIGHFHGP_00990	1.53e-52	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_00991	1.77e-77	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_00992	1.54e-58	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HIGHFHGP_00993	2.27e-168	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
HIGHFHGP_00994	2.38e-83	gloA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIGHFHGP_00996	9.12e-317	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HIGHFHGP_00997	7.93e-140	-	-	-	E	-	-	-	haloacid dehalogenase-like hydrolase
HIGHFHGP_00998	8.87e-210	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HIGHFHGP_00999	8.43e-299	rutG	-	-	F	ko:K02824,ko:K03458	-	ko00000,ko02000	Permease family
HIGHFHGP_01000	0.0	-	-	-	JKL	-	-	-	helicase superfamily c-terminal domain
HIGHFHGP_01001	0.0	nplT	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HIGHFHGP_01002	2.33e-240	pitB	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HIGHFHGP_01003	2.24e-146	-	-	-	P	ko:K07220	-	ko00000	Protein of unknown function DUF47
HIGHFHGP_01004	2.11e-140	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HIGHFHGP_01005	1.16e-285	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_01006	1.01e-13	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HIGHFHGP_01007	1.52e-238	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01008	9.97e-287	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HIGHFHGP_01009	0.0	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HIGHFHGP_01010	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HIGHFHGP_01011	8.19e-146	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HIGHFHGP_01012	6.28e-246	-	-	-	-	-	-	-	-
HIGHFHGP_01013	2.41e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Peptidase family S51
HIGHFHGP_01014	6.16e-138	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HIGHFHGP_01015	1.54e-218	-	-	-	M	-	-	-	pfam nlp p60
HIGHFHGP_01016	5.23e-195	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HIGHFHGP_01017	1.56e-40	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HIGHFHGP_01018	1.54e-69	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HIGHFHGP_01019	4.99e-308	pbuX	-	-	F	ko:K03458	-	ko00000	Permease family
HIGHFHGP_01020	3.1e-137	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIGHFHGP_01021	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HIGHFHGP_01022	4.61e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF4418)
HIGHFHGP_01023	1.05e-273	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIGHFHGP_01024	4.88e-207	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HIGHFHGP_01025	5.26e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIGHFHGP_01026	4.91e-199	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HIGHFHGP_01027	8.3e-115	-	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	cytidine deaminase activity
HIGHFHGP_01028	1.12e-64	-	-	-	S	-	-	-	SdpI/YhfL protein family
HIGHFHGP_01029	1.03e-143	-	-	-	E	-	-	-	Transglutaminase-like superfamily
HIGHFHGP_01030	1.03e-76	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIGHFHGP_01032	7.13e-84	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HIGHFHGP_01033	1.48e-64	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIGHFHGP_01034	3e-25	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HIGHFHGP_01035	3.21e-131	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HIGHFHGP_01038	0.0	-	-	-	S	-	-	-	alpha beta
HIGHFHGP_01039	5.58e-175	-	-	-	K	-	-	-	Putative sugar-binding domain
HIGHFHGP_01040	1.22e-149	-	-	-	G	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01041	8.05e-110	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HIGHFHGP_01042	6.27e-223	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HIGHFHGP_01043	1.91e-52	-	-	-	-	-	-	-	-
HIGHFHGP_01044	2.83e-119	-	-	-	L	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
HIGHFHGP_01045	1.33e-55	umuD	-	-	KT	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	Peptidase S24-like
HIGHFHGP_01046	2.13e-136	-	-	-	L	ko:K03502	-	ko00000,ko03400	Domain of unknown function (DUF4113)
HIGHFHGP_01048	2.01e-150	-	-	-	V	-	-	-	Abi-like protein
HIGHFHGP_01052	3.58e-88	intA	-	-	L	-	-	-	Phage integrase family
HIGHFHGP_01054	3.75e-195	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HIGHFHGP_01056	1.95e-48	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01058	1.08e-05	-	-	-	L	-	-	-	Helix-turn-helix domain
HIGHFHGP_01061	6.41e-19	-	-	-	-	-	-	-	-
HIGHFHGP_01066	1.9e-99	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HIGHFHGP_01067	2.17e-13	-	-	-	S	-	-	-	Helix-turn-helix domain
HIGHFHGP_01071	2.74e-54	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	VirC1 protein
HIGHFHGP_01077	3.54e-155	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_01078	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIGHFHGP_01079	6.88e-198	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01080	3.72e-176	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HIGHFHGP_01081	4.93e-315	-	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HIGHFHGP_01082	1.52e-144	-	-	-	I	-	-	-	Serine aminopeptidase, S33
HIGHFHGP_01083	0.0	-	2.4.1.333	GH94	G	ko:K21298	-	ko00000,ko01000	Glycosyltransferase 36 associated
HIGHFHGP_01084	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HIGHFHGP_01085	7.25e-67	-	-	-	L	ko:K07485	-	ko00000	Transposase
HIGHFHGP_01087	3.18e-139	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
HIGHFHGP_01089	3.14e-22	-	1.1.1.100, 1.1.1.69	-	IQ	ko:K00046,ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HIGHFHGP_01090	4.02e-33	-	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	KR domain
HIGHFHGP_01091	1.37e-48	-	-	-	E	ko:K03293	-	ko00000	PFAM Amino acid
HIGHFHGP_01092	9.92e-23	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HIGHFHGP_01093	3.72e-11	-	-	-	E	ko:K03293	-	ko00000	PFAM Amino acid
HIGHFHGP_01096	1.49e-24	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HIGHFHGP_01097	1.07e-44	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HIGHFHGP_01098	6.98e-64	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Extracellular solute-binding protein
HIGHFHGP_01099	9.33e-133	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HIGHFHGP_01100	1.81e-115	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HIGHFHGP_01101	2.43e-267	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HIGHFHGP_01102	4.29e-298	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HIGHFHGP_01103	5.2e-267	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
HIGHFHGP_01104	1.4e-118	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HIGHFHGP_01105	9.26e-137	-	-	-	L	-	-	-	Winged helix-turn helix
HIGHFHGP_01106	4.21e-15	-	-	-	L	-	-	-	Winged helix-turn helix
HIGHFHGP_01107	5.26e-21	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HIGHFHGP_01108	9.91e-166	-	5.4.2.12	-	G	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HIGHFHGP_01109	5.23e-76	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HIGHFHGP_01110	6.59e-48	-	-	-	-	-	-	-	-
HIGHFHGP_01111	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIGHFHGP_01112	2.12e-99	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIGHFHGP_01113	6.46e-240	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HIGHFHGP_01114	2.48e-91	-	3.4.23.43	-	S	ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type IV leader peptidase family
HIGHFHGP_01115	4.31e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HIGHFHGP_01116	0.0	aroB	2.7.1.71, 4.2.3.4	-	H	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HIGHFHGP_01117	4.94e-103	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HIGHFHGP_01118	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIGHFHGP_01119	0.0	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HIGHFHGP_01120	0.0	sufB	-	-	O	ko:K09014	-	ko00000	FeS assembly protein SufB
HIGHFHGP_01121	6.16e-301	sufD	-	-	O	ko:K09015	-	ko00000	FeS assembly protein SufD
HIGHFHGP_01122	2.81e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HIGHFHGP_01123	1.07e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIGHFHGP_01124	8.33e-133	iscU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HIGHFHGP_01125	5.16e-141	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HIGHFHGP_01126	1.86e-308	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HIGHFHGP_01127	2.26e-211	spoU2	-	-	J	-	-	-	SpoU rRNA Methylase family
HIGHFHGP_01129	4.41e-175	-	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HIGHFHGP_01130	2.76e-76	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HIGHFHGP_01131	9.79e-278	phoH	-	-	T	ko:K06217	-	ko00000	PhoH-like protein
HIGHFHGP_01132	1.33e-133	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIGHFHGP_01133	0.0	corC	-	-	S	-	-	-	CBS domain
HIGHFHGP_01134	3.86e-236	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIGHFHGP_01135	0.0	fadD2	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HIGHFHGP_01136	2.32e-261	pntA	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	NAD(P) transhydrogenase subunit alpha part 1 K00324
HIGHFHGP_01137	3.55e-58	pntAB	1.6.1.2	-	C	ko:K00324	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	4TM region of pyridine nucleotide transhydrogenase, mitoch
HIGHFHGP_01138	2.11e-308	pntB	1.6.1.2	-	C	ko:K00325	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HIGHFHGP_01139	1.77e-299	-	-	-	EGP	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HIGHFHGP_01140	1.75e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HIGHFHGP_01141	2.72e-288	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Amino-transferase class IV
HIGHFHGP_01142	1.07e-159	mazG	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01143	4.82e-179	-	-	-	S	-	-	-	UPF0126 domain
HIGHFHGP_01144	4.75e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HIGHFHGP_01145	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIGHFHGP_01146	0.0	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HIGHFHGP_01148	9.59e-245	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_01149	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase NADPH large subunit
HIGHFHGP_01150	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HIGHFHGP_01151	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HIGHFHGP_01152	0.0	-	-	-	S	-	-	-	Glycosyl hydrolases related to GH101 family, GH129
HIGHFHGP_01153	1.98e-105	-	-	-	-	-	-	-	-
HIGHFHGP_01154	2.77e-311	glgA	2.4.1.342	GT4	G	ko:K16148	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Starch synthase catalytic domain
HIGHFHGP_01155	4.88e-201	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01156	7.27e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIGHFHGP_01158	2.92e-99	-	-	-	G	ko:K02445,ko:K03762	-	ko00000,ko02000	transmembrane transporter activity
HIGHFHGP_01160	8.71e-261	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HIGHFHGP_01161	1.73e-24	-	-	-	L	-	-	-	Transposase, Mutator family
HIGHFHGP_01162	1.41e-115	-	-	-	L	-	-	-	Transposase, Mutator family
HIGHFHGP_01163	3.76e-122	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Redoxin
HIGHFHGP_01164	1.11e-177	-	-	-	-	-	-	-	-
HIGHFHGP_01165	3.63e-76	CP_1020	-	-	S	-	-	-	zinc ion binding
HIGHFHGP_01166	1.88e-16	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HIGHFHGP_01167	2.85e-41	-	-	-	S	-	-	-	MazG-like family
HIGHFHGP_01168	4.71e-253	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HIGHFHGP_01169	1.24e-21	-	-	-	E	-	-	-	Rard protein
HIGHFHGP_01172	1.08e-39	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	EamA-like transporter family
HIGHFHGP_01173	9.92e-161	-	-	-	S	-	-	-	Plasmid pRiA4b ORF-3-like protein
HIGHFHGP_01174	2.71e-166	-	-	-	-	-	-	-	-
HIGHFHGP_01176	1.18e-227	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HIGHFHGP_01177	1.12e-116	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
HIGHFHGP_01178	4.02e-187	-	-	-	S	-	-	-	phosphoesterase or phosphohydrolase
HIGHFHGP_01179	4.16e-181	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIGHFHGP_01181	7.17e-171	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HIGHFHGP_01182	9.05e-257	trmI	2.1.1.219, 2.1.1.220	-	J	ko:K07442	-	ko00000,ko01000,ko03016	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HIGHFHGP_01183	9.69e-128	sixA	-	-	T	ko:K08296	-	ko00000,ko01000	Phosphoglycerate mutase family
HIGHFHGP_01185	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HIGHFHGP_01186	9.57e-209	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HIGHFHGP_01187	3.45e-239	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HIGHFHGP_01188	0.0	glnE	2.7.7.42, 2.7.7.89	-	H	ko:K00982	-	ko00000,ko01000	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HIGHFHGP_01189	4.95e-226	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HIGHFHGP_01190	2.61e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HIGHFHGP_01191	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIGHFHGP_01192	6.06e-224	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HIGHFHGP_01193	1.3e-201	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HIGHFHGP_01194	3.99e-232	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIGHFHGP_01195	4.64e-160	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIGHFHGP_01196	3.09e-39	-	-	-	-	-	-	-	-
HIGHFHGP_01197	1.67e-272	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01198	1.55e-221	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HIGHFHGP_01199	1.93e-157	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HIGHFHGP_01200	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIGHFHGP_01201	0.0	ybiT	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HIGHFHGP_01202	5.24e-168	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HIGHFHGP_01203	5.4e-34	-	-	-	G	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01204	1.09e-29	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
HIGHFHGP_01205	6.01e-76	-	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Hypothetical bacterial integral membrane protein (Trep_Strep)
HIGHFHGP_01206	1.67e-295	-	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01207	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIGHFHGP_01208	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIGHFHGP_01209	2e-238	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Shikimate dehydrogenase substrate binding domain
HIGHFHGP_01210	6.34e-228	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HIGHFHGP_01211	2.86e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HIGHFHGP_01212	4.15e-278	pgk	2.7.2.3, 5.3.1.1	-	F	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Phosphoglycerate kinase
HIGHFHGP_01213	1.7e-188	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIGHFHGP_01214	2.51e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HIGHFHGP_01215	3.25e-223	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HIGHFHGP_01216	9.92e-206	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIGHFHGP_01217	0.0	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase, class I II
HIGHFHGP_01218	8e-245	-	-	-	-	-	-	-	-
HIGHFHGP_01219	3.05e-303	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HIGHFHGP_01220	2.71e-259	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HIGHFHGP_01221	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HIGHFHGP_01222	1.16e-243	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIGHFHGP_01223	5.4e-273	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIGHFHGP_01224	9.17e-201	-	-	-	G	-	-	-	Fructosamine kinase
HIGHFHGP_01225	1.51e-201	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HIGHFHGP_01226	6.22e-169	-	-	-	S	-	-	-	PAC2 family
HIGHFHGP_01232	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIGHFHGP_01233	7.63e-143	-	2.7.7.53	-	FG	ko:K19710	ko00230,map00230	ko00000,ko00001,ko01000	HIT domain
HIGHFHGP_01234	1.19e-156	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HIGHFHGP_01235	4.21e-131	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HIGHFHGP_01236	5.04e-139	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIGHFHGP_01237	5.01e-253	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIGHFHGP_01238	2.53e-71	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
HIGHFHGP_01239	3.21e-130	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIGHFHGP_01240	1.4e-280	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HIGHFHGP_01241	5.31e-211	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HIGHFHGP_01242	1.39e-296	-	-	-	-	-	-	-	-
HIGHFHGP_01243	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HIGHFHGP_01244	2.5e-43	-	-	-	-	-	-	-	-
HIGHFHGP_01245	1.34e-181	-	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HIGHFHGP_01246	9.06e-184	rluB	5.4.99.19, 5.4.99.22	-	J	ko:K06178,ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HIGHFHGP_01247	0.0	der	-	-	F	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HIGHFHGP_01249	1.53e-207	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HIGHFHGP_01250	0.0	ugp	2.7.7.9	-	G	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HIGHFHGP_01251	0.0	-	-	-	K	-	-	-	WYL domain
HIGHFHGP_01252	4.22e-70	-	-	-	-	-	-	-	-
HIGHFHGP_01253	0.0	helY	-	-	L	ko:K03727	-	ko00000,ko01000	DEAD DEAH box helicase
HIGHFHGP_01254	3.18e-81	rbpA	-	-	K	-	-	-	Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HIGHFHGP_01255	2.61e-179	nt5e	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD-hyrolase-like
HIGHFHGP_01256	1.41e-45	-	-	-	-	-	-	-	-
HIGHFHGP_01257	3.47e-205	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Phosphotransferase enzyme family
HIGHFHGP_01258	4.37e-84	-	-	-	-	-	-	-	-
HIGHFHGP_01259	3.85e-144	merR2	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HIGHFHGP_01260	2.02e-97	garA	-	-	T	-	-	-	Inner membrane component of T3SS, cytoplasmic domain
HIGHFHGP_01261	5.34e-180	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HIGHFHGP_01262	6.08e-61	sbp	-	-	S	-	-	-	Protein of unknown function (DUF1290)
HIGHFHGP_01263	7.29e-220	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF881)
HIGHFHGP_01264	6.65e-138	pgsA2	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIGHFHGP_01265	8.75e-200	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HIGHFHGP_01266	5.07e-56	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP pyrophosphohydrolase
HIGHFHGP_01267	7.16e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribulose-phosphate 3-epimerase
HIGHFHGP_01268	5.51e-240	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIGHFHGP_01269	7.23e-207	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HIGHFHGP_01270	0.0	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HIGHFHGP_01271	6.15e-169	-	-	-	S	-	-	-	SOS response associated peptidase (SRAP)
HIGHFHGP_01272	2.49e-195	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HIGHFHGP_01273	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HIGHFHGP_01274	5.53e-160	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01275	3.31e-238	-	-	-	V	-	-	-	VanZ like family
HIGHFHGP_01276	7.73e-84	-	-	-	J	-	-	-	Aminoacyl-tRNA editing domain
HIGHFHGP_01277	6.52e-55	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HIGHFHGP_01278	1.83e-12	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIGHFHGP_01279	6.6e-113	-	-	-	K	-	-	-	FR47-like protein
HIGHFHGP_01281	7.06e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HIGHFHGP_01282	3.24e-204	-	-	-	C	-	-	-	Aldo/keto reductase family
HIGHFHGP_01283	3.34e-19	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HIGHFHGP_01284	1.58e-103	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HIGHFHGP_01285	1.71e-84	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIGHFHGP_01286	3.03e-63	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_01287	6.33e-96	-	-	-	K	-	-	-	Bacterial regulatory proteins, luxR family
HIGHFHGP_01288	4.94e-26	-	-	-	-	-	-	-	-
HIGHFHGP_01289	4.59e-112	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_01290	3.55e-64	-	-	-	-	-	-	-	-
HIGHFHGP_01291	9.39e-154	-	-	-	-	-	-	-	-
HIGHFHGP_01294	9.03e-12	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HIGHFHGP_01295	1.75e-16	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_01296	6.09e-257	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_01297	3.69e-166	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HIGHFHGP_01298	4.9e-123	-	-	-	-	-	-	-	-
HIGHFHGP_01299	2.91e-200	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIGHFHGP_01300	7.75e-161	-	-	-	Q	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01301	1.23e-231	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HIGHFHGP_01302	3.65e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HIGHFHGP_01303	1.04e-64	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
HIGHFHGP_01304	8.73e-34	-	-	-	G	-	-	-	Transporter major facilitator family protein
HIGHFHGP_01305	0.0	-	-	-	E	ko:K16235	-	ko00000,ko02000	amino acid
HIGHFHGP_01306	5.32e-11	-	-	-	-	-	-	-	-
HIGHFHGP_01307	5.5e-84	-	-	-	K	-	-	-	Protein of unknown function, DUF488
HIGHFHGP_01308	2.79e-97	-	-	-	-	-	-	-	-
HIGHFHGP_01309	1.37e-226	-	-	-	-	-	-	-	-
HIGHFHGP_01310	1.15e-119	-	-	-	S	ko:K09974	-	ko00000	Domain of unknown function (DUF1287)
HIGHFHGP_01311	0.0	trpE	4.1.3.27	-	E	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIGHFHGP_01312	2.28e-93	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HIGHFHGP_01313	4.13e-180	hisF	4.1.3.27	-	E	ko:K01657,ko:K02500	ko00340,ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00340,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HIGHFHGP_01314	6.98e-99	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HIGHFHGP_01315	7.84e-286	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HIGHFHGP_01316	8.23e-223	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Cytidylyltransferase family
HIGHFHGP_01317	7.06e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIGHFHGP_01318	3.81e-171	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HIGHFHGP_01319	7.92e-187	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIGHFHGP_01320	2.69e-192	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HIGHFHGP_01321	1.96e-113	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIGHFHGP_01322	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	long-chain-fatty acid CoA ligase
HIGHFHGP_01323	5.83e-120	-	-	-	-	-	-	-	-
HIGHFHGP_01324	1.25e-263	guaB3	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	IMP dehydrogenase family protein
HIGHFHGP_01325	2e-308	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the isocitrate and isopropylmalate dehydrogenases family
HIGHFHGP_01326	0.0	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
HIGHFHGP_01327	7.62e-113	-	-	-	M	-	-	-	Peptidase family M23
HIGHFHGP_01329	1.77e-66	-	-	-	L	-	-	-	Phage integrase family
HIGHFHGP_01330	2.93e-05	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA N-terminal domain
HIGHFHGP_01332	3.69e-185	-	-	-	S	-	-	-	Fic/DOC family
HIGHFHGP_01333	5.61e-58	-	-	-	L	-	-	-	PFAM Relaxase mobilization nuclease family protein
HIGHFHGP_01334	8.96e-252	-	-	-	V	ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HIGHFHGP_01335	2.53e-181	-	-	-	S	ko:K20460	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HIGHFHGP_01336	4.89e-183	-	-	-	-	ko:K20461	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HIGHFHGP_01337	3.84e-91	-	-	-	-	-	-	-	-
HIGHFHGP_01339	7.88e-304	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_01340	5.21e-155	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HIGHFHGP_01342	1.09e-248	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIGHFHGP_01343	6.7e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	FR47-like protein
HIGHFHGP_01344	1.98e-201	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Glycoprotease family
HIGHFHGP_01345	1.06e-112	tsaE	-	-	S	ko:K06925	-	ko00000,ko03016	Threonylcarbamoyl adenosine biosynthesis protein TsaE
HIGHFHGP_01346	1.15e-214	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HIGHFHGP_01347	0.0	-	-	-	D	-	-	-	Transglutaminase-like superfamily
HIGHFHGP_01348	4.25e-226	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein
HIGHFHGP_01349	1.17e-44	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
HIGHFHGP_01350	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HIGHFHGP_01351	1.52e-205	-	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HIGHFHGP_01352	4.06e-217	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HIGHFHGP_01353	2.1e-215	gpmB	3.1.3.85, 5.4.2.11	-	G	ko:K01834,ko:K22306	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
HIGHFHGP_01354	2.1e-296	-	-	-	L	-	-	-	ribosomal rna small subunit methyltransferase
HIGHFHGP_01355	2.86e-93	pdxH	-	-	S	ko:K07006	-	ko00000	Pfam:Pyridox_oxidase
HIGHFHGP_01356	1.42e-219	-	-	-	EG	-	-	-	EamA-like transporter family
HIGHFHGP_01357	5.06e-169	-	-	-	C	-	-	-	Putative TM nitroreductase
HIGHFHGP_01358	3.1e-42	-	-	-	-	-	-	-	-
HIGHFHGP_01359	0.0	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HIGHFHGP_01360	3.47e-307	-	-	-	G	-	-	-	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HIGHFHGP_01361	2.4e-174	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_01362	1.14e-278	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HIGHFHGP_01363	2.82e-160	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01364	5.02e-155	-	-	-	G	ko:K02025,ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01365	5.09e-223	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_01366	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HIGHFHGP_01367	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HIGHFHGP_01368	1.95e-109	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIGHFHGP_01369	1.32e-30	lppD	-	-	S	-	-	-	Appr-1'-p processing enzyme
HIGHFHGP_01370	4.4e-52	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01371	5.52e-74	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_01372	0.0	-	-	-	L	-	-	-	PFAM Integrase catalytic
HIGHFHGP_01373	4.85e-185	istB	-	-	L	-	-	-	IstB-like ATP binding protein
HIGHFHGP_01374	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01376	4.51e-148	-	-	-	K	-	-	-	WHG domain
HIGHFHGP_01377	4.52e-119	-	-	-	Q	-	-	-	4'-phosphopantetheinyl transferase superfamily
HIGHFHGP_01378	4.77e-75	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_01379	4.4e-52	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01380	4.36e-203	-	-	-	S	-	-	-	Fic/DOC family
HIGHFHGP_01382	7.08e-223	-	-	-	V	-	-	-	Abi-like protein
HIGHFHGP_01383	6.64e-132	ppiA	5.2.1.8	-	G	ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIGHFHGP_01384	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIGHFHGP_01385	4.13e-109	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HIGHFHGP_01386	4.95e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4193)
HIGHFHGP_01387	6.82e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF3071)
HIGHFHGP_01388	7.3e-299	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HIGHFHGP_01389	0.0	gyrA2	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HIGHFHGP_01390	5.69e-126	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_01391	5.54e-25	-	-	-	K	ko:K07506	-	ko00000,ko03000	helix_turn_helix, arabinose operon control protein
HIGHFHGP_01394	0.0	lhr	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HIGHFHGP_01395	5.78e-219	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIGHFHGP_01396	2.17e-285	-	-	-	G	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01397	0.0	gyrB2	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	DNA topoisomerase (ATP-hydrolyzing)
HIGHFHGP_01398	4.32e-242	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIGHFHGP_01399	5.66e-145	-	-	-	-	-	-	-	-
HIGHFHGP_01400	4.11e-252	idsA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HIGHFHGP_01401	0.0	pknL	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	PASTA
HIGHFHGP_01402	2.4e-169	plsC2	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Phosphate acyltransferases
HIGHFHGP_01403	1.89e-158	-	-	-	-	-	-	-	-
HIGHFHGP_01404	4.2e-242	trpD	2.4.2.18	-	F	ko:K00766	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HIGHFHGP_01405	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIGHFHGP_01406	1.24e-154	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIGHFHGP_01407	1.58e-133	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HIGHFHGP_01408	5.78e-253	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIGHFHGP_01409	5.38e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3046)
HIGHFHGP_01410	1.55e-99	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIGHFHGP_01411	7.04e-121	cinA	3.5.1.42	-	S	ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HIGHFHGP_01412	1.4e-151	pgsA	2.7.8.41, 2.7.8.5	-	I	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIGHFHGP_01413	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	FtsK SpoIIIE family protein
HIGHFHGP_01414	1.35e-193	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HIGHFHGP_01415	7.11e-228	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIGHFHGP_01416	0.0	miaB	2.8.4.3	-	H	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HIGHFHGP_01417	1.34e-190	ywaC	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Region found in RelA / SpoT proteins
HIGHFHGP_01418	9.06e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HIGHFHGP_01419	1.64e-174	-	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HIGHFHGP_01420	2.33e-155	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01421	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HIGHFHGP_01422	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HIGHFHGP_01423	2.62e-127	-	-	-	-	-	-	-	-
HIGHFHGP_01424	1.31e-306	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIGHFHGP_01425	2.46e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF3159)
HIGHFHGP_01426	1.02e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF3710)
HIGHFHGP_01427	4.59e-217	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease/Exonuclease/phosphatase family
HIGHFHGP_01428	0.0	-	-	-	EP	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HIGHFHGP_01429	2.21e-230	dppC	-	-	EP	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HIGHFHGP_01430	1.39e-204	dppB	-	-	EP	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01431	0.0	dppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HIGHFHGP_01432	3.61e-243	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HIGHFHGP_01433	1.23e-188	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_01434	0.0	-	-	-	MV	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HIGHFHGP_01435	2.36e-56	-	-	-	-	-	-	-	-
HIGHFHGP_01436	9.56e-243	tyrA	1.3.1.12	-	E	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydrogenase
HIGHFHGP_01437	1.41e-241	pheA	4.2.1.51, 5.4.99.5	-	E	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HIGHFHGP_01438	4.03e-101	-	-	-	-	-	-	-	-
HIGHFHGP_01439	0.0	typA	-	-	T	ko:K06207	-	ko00000	Elongation factor G C-terminus
HIGHFHGP_01440	5.96e-139	-	-	-	K	-	-	-	Virulence activator alpha C-term
HIGHFHGP_01441	5.21e-177	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01442	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIGHFHGP_01443	3.49e-24	nanT	-	-	U	ko:K03290,ko:K08178,ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HIGHFHGP_01444	1.92e-301	iscS1	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class-V
HIGHFHGP_01445	9.16e-209	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, N-terminal domain
HIGHFHGP_01446	0.0	nadB	1.4.3.16, 2.4.2.19	-	H	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HIGHFHGP_01447	0.0	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HIGHFHGP_01448	3.89e-205	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX hydrolase
HIGHFHGP_01449	1.22e-147	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIGHFHGP_01450	1.56e-193	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIGHFHGP_01451	6.89e-193	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HIGHFHGP_01452	1.42e-201	xerD	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	recombinase XerD
HIGHFHGP_01453	5.26e-245	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HIGHFHGP_01454	7.76e-81	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIGHFHGP_01455	2.72e-34	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L35
HIGHFHGP_01456	1.72e-157	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIGHFHGP_01457	4.29e-08	-	-	-	S	-	-	-	Spermine/spermidine synthase domain
HIGHFHGP_01458	5.45e-173	-	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamin pyrophosphokinase, vitamin B1 binding domain
HIGHFHGP_01459	5.83e-251	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIGHFHGP_01460	4.92e-115	ybaK	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIGHFHGP_01461	2.06e-233	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HIGHFHGP_01462	8.5e-245	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HIGHFHGP_01463	1.77e-235	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HIGHFHGP_01464	2.29e-68	-	-	-	-	-	-	-	-
HIGHFHGP_01465	1.11e-176	sigH	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HIGHFHGP_01466	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIGHFHGP_01467	2.02e-247	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_01468	1.52e-63	-	-	-	V	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_01469	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HIGHFHGP_01470	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain
HIGHFHGP_01471	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Aminopeptidase P, N-terminal domain
HIGHFHGP_01472	1.77e-124	-	-	-	F	-	-	-	NUDIX domain
HIGHFHGP_01473	1.18e-312	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Amidohydrolase family
HIGHFHGP_01474	1.15e-193	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIGHFHGP_01475	4.56e-266	-	-	-	GK	-	-	-	ROK family
HIGHFHGP_01476	5.74e-211	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIGHFHGP_01477	6.67e-281	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIGHFHGP_01478	2.27e-214	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HIGHFHGP_01479	8.6e-110	-	-	-	G	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01480	1.68e-55	-	-	-	G	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01481	1.74e-112	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIGHFHGP_01483	6.82e-230	ftsQ	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein FtsQ
HIGHFHGP_01484	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HIGHFHGP_01485	8e-275	murG	2.4.1.227, 6.3.2.8	GT28	M	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIGHFHGP_01486	9.99e-288	ftsW	2.4.1.227	GT28	D	ko:K02563,ko:K03588	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011,ko02000,ko03036	Belongs to the SEDS family
HIGHFHGP_01487	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIGHFHGP_01488	9.14e-263	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIGHFHGP_01489	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIGHFHGP_01490	1.51e-199	-	-	-	M	-	-	-	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIGHFHGP_01491	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Penicillin-binding protein, transpeptidase domain protein
HIGHFHGP_01492	2.23e-91	-	-	-	D	-	-	-	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HIGHFHGP_01493	8.49e-243	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIGHFHGP_01494	1.29e-117	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HIGHFHGP_01495	0.0	-	-	-	L	-	-	-	DNA helicase
HIGHFHGP_01496	4.79e-292	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HIGHFHGP_01497	4.08e-101	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIGHFHGP_01498	5e-68	-	-	-	M	-	-	-	Lysin motif
HIGHFHGP_01499	4.82e-165	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIGHFHGP_01500	1.55e-204	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIGHFHGP_01501	1.61e-225	ldh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HIGHFHGP_01502	0.0	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIGHFHGP_01503	2.83e-159	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase (PrmA)
HIGHFHGP_01504	0.0	hrpA	3.6.4.13	-	L	ko:K03578	-	ko00000,ko01000	Helicase associated domain (HA2) Add an annotation
HIGHFHGP_01505	4.33e-280	-	-	-	EGP	ko:K18567,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HIGHFHGP_01506	0.0	glnA2	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HIGHFHGP_01507	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2252)
HIGHFHGP_01508	7.13e-169	hisA	5.3.1.16, 5.3.1.24	-	E	ko:K01814,ko:K01817	ko00340,ko00400,ko01100,ko01110,ko01130,ko01230,map00340,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis protein
HIGHFHGP_01509	2.07e-155	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HIGHFHGP_01510	2.17e-162	-	-	-	-	-	-	-	-
HIGHFHGP_01511	4.75e-144	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HIGHFHGP_01512	1.29e-278	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HIGHFHGP_01513	0.0	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HIGHFHGP_01514	1.2e-70	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Acylphosphatase
HIGHFHGP_01515	3.87e-199	-	-	-	S	-	-	-	Aldo/keto reductase family
HIGHFHGP_01516	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HIGHFHGP_01517	2.45e-213	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HIGHFHGP_01518	1.31e-92	-	-	-	S	-	-	-	Amidohydrolase
HIGHFHGP_01519	6.98e-103	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HIGHFHGP_01521	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HIGHFHGP_01522	7.61e-215	dkgV	-	-	C	-	-	-	Aldo/keto reductase family
HIGHFHGP_01524	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HIGHFHGP_01525	1.68e-253	-	-	-	K	-	-	-	WYL domain
HIGHFHGP_01526	8.3e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HIGHFHGP_01527	5.76e-115	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIGHFHGP_01528	7.14e-106	-	-	-	V	-	-	-	DivIVA protein
HIGHFHGP_01529	3.44e-60	-	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HIGHFHGP_01530	1.42e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIGHFHGP_01531	8.65e-275	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIGHFHGP_01532	0.0	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIGHFHGP_01533	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HIGHFHGP_01534	1.15e-149	-	-	-	-	-	-	-	-
HIGHFHGP_01535	2.02e-170	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HIGHFHGP_01536	7.65e-121	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HIGHFHGP_01537	1.44e-81	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HIGHFHGP_01538	5.9e-120	-	-	-	-	-	-	-	-
HIGHFHGP_01539	5.91e-209	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIGHFHGP_01540	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HIGHFHGP_01541	1.08e-287	-	-	-	O	ko:K13525	ko04141,ko05134,map04141,map05134	ko00000,ko00001,ko00002,ko03019,ko04131,ko04147	AAA domain (Cdc48 subfamily)
HIGHFHGP_01542	1.02e-185	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HIGHFHGP_01543	4.71e-81	-	-	-	S	-	-	-	Thiamine-binding protein
HIGHFHGP_01544	0.0	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HIGHFHGP_01545	6.5e-294	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_01546	5.01e-159	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HIGHFHGP_01547	2.01e-244	-	-	-	-	-	-	-	-
HIGHFHGP_01548	0.0	-	-	-	O	ko:K13963	ko05146,map05146	ko00000,ko00001	SERine Proteinase INhibitors
HIGHFHGP_01549	8.6e-250	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_01550	1.8e-306	lacY	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HIGHFHGP_01551	0.0	fosC	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HIGHFHGP_01552	1.33e-180	ppgK	2.7.1.2, 2.7.1.63	-	GK	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIGHFHGP_01553	6.17e-191	-	-	-	C	-	-	-	Putative TM nitroreductase
HIGHFHGP_01554	1.55e-252	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HIGHFHGP_01555	4.04e-134	-	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIGHFHGP_01556	0.0	-	-	-	GP	ko:K16785,ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_01557	4.67e-63	-	-	-	J	ko:K07574	-	ko00000,ko03009	CRS1_YhbY
HIGHFHGP_01558	1.66e-70	-	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HIGHFHGP_01559	2.26e-67	-	-	-	-	-	-	-	-
HIGHFHGP_01560	6.69e-238	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HIGHFHGP_01561	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01562	4.1e-41	mtrB	2.7.13.3	-	T	ko:K07636,ko:K07654	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HIGHFHGP_01563	1.35e-13	mtrA	-	-	KT	ko:K07670	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HIGHFHGP_01564	0.0	rarA	-	-	L	ko:K07478	-	ko00000	Recombination factor protein RarA
HIGHFHGP_01565	0.0	-	-	-	L	-	-	-	DEAD DEAH box helicase
HIGHFHGP_01566	3.61e-255	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HIGHFHGP_01568	0.0	-	-	-	EK	ko:K05825,ko:K18907	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko00002,ko01000,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HIGHFHGP_01569	3.25e-145	-	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HIGHFHGP_01570	0.0	-	-	-	I	-	-	-	PAP2 superfamily
HIGHFHGP_01571	1.27e-252	gluD	-	-	E	ko:K10007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01572	8.52e-144	gluC	-	-	E	ko:K10006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01573	3.16e-189	gluB	-	-	ET	ko:K10005	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HIGHFHGP_01574	9.45e-198	gluA	-	-	E	ko:K10008	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding protein of ABC transporter for glutamate K02028
HIGHFHGP_01575	4.46e-132	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HIGHFHGP_01576	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HIGHFHGP_01577	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Histidyl-tRNA synthetase
HIGHFHGP_01578	8.64e-317	-	-	-	S	-	-	-	Domain of Unknown Function (DUF349)
HIGHFHGP_01579	0.0	-	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HIGHFHGP_01580	1.36e-143	-	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
HIGHFHGP_01581	7.17e-212	proP	-	-	EGP	ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HIGHFHGP_01583	0.0	-	-	-	QT	-	-	-	Purine catabolism regulatory protein-like family
HIGHFHGP_01584	0.0	codA	3.5.4.1, 3.5.4.21	-	F	ko:K01485,ko:K03365	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HIGHFHGP_01585	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	ATPase family associated with various cellular activities (AAA)
HIGHFHGP_01586	3.99e-231	uspA	-	-	T	-	-	-	Belongs to the universal stress protein A family
HIGHFHGP_01587	3.66e-232	-	-	-	S	-	-	-	Protein of unknown function (DUF3027)
HIGHFHGP_01588	1.75e-87	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HIGHFHGP_01589	0.0	phoR	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HIGHFHGP_01590	1.23e-170	phoP	-	-	KT	ko:K02483	-	ko00000,ko02022	Response regulator receiver domain protein
HIGHFHGP_01591	1.79e-146	-	-	-	-	-	-	-	-
HIGHFHGP_01592	6.57e-54	-	-	-	S	-	-	-	Proteins of 100 residues with WXG
HIGHFHGP_01593	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIGHFHGP_01594	1.54e-51	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HIGHFHGP_01595	3.95e-125	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HIGHFHGP_01596	5.7e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIGHFHGP_01597	1.31e-246	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HIGHFHGP_01598	3.97e-210	-	-	-	S	-	-	-	Protein of unknown function DUF58
HIGHFHGP_01599	3.26e-119	-	-	-	-	-	-	-	-
HIGHFHGP_01600	6.19e-241	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HIGHFHGP_01601	1.21e-212	-	-	-	S	ko:K07114	-	ko00000,ko02000	von Willebrand factor (vWF) type A domain
HIGHFHGP_01602	8.64e-76	-	-	-	-	-	-	-	-
HIGHFHGP_01603	0.0	-	-	-	S	-	-	-	PGAP1-like protein
HIGHFHGP_01604	1.23e-142	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HIGHFHGP_01605	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminal
HIGHFHGP_01606	0.0	-	-	-	S	-	-	-	Lysylphosphatidylglycerol synthase TM region
HIGHFHGP_01607	3.31e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HIGHFHGP_01608	0.0	pafA	6.3.1.19	-	O	ko:K13571	-	ko00000,ko00002,ko01000,ko03051	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HIGHFHGP_01609	8.43e-16	pup	-	-	S	ko:K13570	-	ko00000,ko04121	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HIGHFHGP_01610	4.8e-224	-	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase family
HIGHFHGP_01611	0.0	dop	3.5.1.119	-	S	ko:K20814	-	ko00000,ko01000,ko03051	Pup-ligase protein
HIGHFHGP_01612	1.06e-173	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
HIGHFHGP_01613	2.06e-229	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
HIGHFHGP_01614	2.2e-62	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HIGHFHGP_01615	1.9e-104	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIGHFHGP_01616	3.14e-94	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIGHFHGP_01617	0.0	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
HIGHFHGP_01618	9.43e-172	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HIGHFHGP_01619	0.0	arc	-	-	O	ko:K13527	ko03050,map03050	ko00000,ko00001,ko00002,ko03051	AAA ATPase forming ring-shaped complexes
HIGHFHGP_01620	3.4e-162	-	-	-	S	-	-	-	SNARE associated Golgi protein
HIGHFHGP_01621	5.36e-152	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HIGHFHGP_01622	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIGHFHGP_01623	7.18e-170	-	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HIGHFHGP_01624	1.47e-241	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIGHFHGP_01625	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HIGHFHGP_01626	5.45e-61	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIGHFHGP_01627	1.6e-289	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIGHFHGP_01628	4.67e-196	-	-	-	G	-	-	-	Fic/DOC family
HIGHFHGP_01630	1.08e-139	vpr	-	-	O	-	-	-	Subtilase family
HIGHFHGP_01631	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIGHFHGP_01632	4.23e-119	-	-	-	S	-	-	-	Aldo/keto reductase family
HIGHFHGP_01633	5.21e-173	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIGHFHGP_01634	6.08e-168	iunH2	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HIGHFHGP_01635	1.1e-151	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_01636	2.38e-133	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HIGHFHGP_01637	3.22e-118	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01638	1.6e-134	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01639	2.59e-90	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HIGHFHGP_01640	5.41e-75	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HIGHFHGP_01641	1.46e-113	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HIGHFHGP_01642	5.63e-116	rbsK	2.7.1.15	-	G	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIGHFHGP_01643	4.15e-63	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HIGHFHGP_01644	7.27e-121	-	-	-	L	ko:K07483	-	ko00000	Integrase core domain
HIGHFHGP_01645	1.53e-43	-	-	-	L	ko:K07483	-	ko00000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01646	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HIGHFHGP_01647	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_01648	5.63e-114	-	-	-	K	-	-	-	MarR family
HIGHFHGP_01649	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HIGHFHGP_01650	6.59e-109	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_01651	2.12e-54	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_01652	3.96e-141	-	-	-	G	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01653	2.24e-100	-	-	-	I	-	-	-	Hydrolase, alpha beta domain protein
HIGHFHGP_01654	9.37e-18	-	-	-	P	-	-	-	COG1275 Tellurite resistance protein and related permeases
HIGHFHGP_01655	1.69e-270	-	3.2.1.4, 3.2.1.58	GH5,GH9	G	ko:K01179,ko:K01210	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HIGHFHGP_01656	1.48e-90	-	-	-	S	-	-	-	Nucleotidyltransferase substrate binding protein like
HIGHFHGP_01657	7.12e-62	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HIGHFHGP_01658	1.84e-256	-	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HIGHFHGP_01659	2.19e-308	-	-	-	S	-	-	-	Protein of unknown function (DUF4038)
HIGHFHGP_01660	1.3e-102	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_01661	1.8e-261	-	-	-	G	-	-	-	Transporter major facilitator family protein
HIGHFHGP_01662	1.11e-64	-	-	-	K	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIGHFHGP_01664	9.04e-24	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_01665	3.52e-87	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HIGHFHGP_01666	1.65e-31	-	-	-	K	-	-	-	Antidote-toxin recognition MazE, bacterial antitoxin
HIGHFHGP_01667	4.11e-50	-	-	-	S	-	-	-	PIN domain
HIGHFHGP_01668	0.0	bgl2	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HIGHFHGP_01669	2.72e-160	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
HIGHFHGP_01670	4.83e-187	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01671	6.87e-143	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HIGHFHGP_01672	2.73e-141	-	-	-	EP	ko:K02031,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01673	2.89e-236	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein, family 5
HIGHFHGP_01674	2.06e-73	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_01675	1.91e-16	-	-	-	K	ko:K02855,ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022,ko03000	sequence-specific DNA binding
HIGHFHGP_01676	8.9e-248	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HIGHFHGP_01677	2.71e-227	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein, family 5
HIGHFHGP_01678	5.17e-153	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HIGHFHGP_01679	0.0	egtA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Glutamate-cysteine ligase family 2(GCS2)
HIGHFHGP_01680	0.0	hgdC	-	-	I	-	-	-	CoA enzyme activase uncharacterised domain (DUF2229)
HIGHFHGP_01681	2.21e-172	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HIGHFHGP_01682	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HIGHFHGP_01683	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIGHFHGP_01684	1.02e-56	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIGHFHGP_01685	3.05e-121	ywrO	-	-	S	-	-	-	Flavodoxin-like fold
HIGHFHGP_01686	0.0	fadD3	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HIGHFHGP_01687	3.3e-85	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIGHFHGP_01688	8.67e-101	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HIGHFHGP_01690	1.36e-265	-	-	-	S	ko:K18353	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01504	Endonuclease/Exonuclease/phosphatase family
HIGHFHGP_01691	2.39e-228	ppx1	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx/GppA phosphatase family
HIGHFHGP_01692	3.68e-298	aspB	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HIGHFHGP_01693	3.69e-258	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HIGHFHGP_01694	8.56e-111	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HIGHFHGP_01695	1.5e-129	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_01696	0.0	-	-	-	KL	-	-	-	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01697	3.06e-219	dapD	2.3.1.117	-	E	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HIGHFHGP_01698	1.06e-315	gltA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Citrate synthase, C-terminal domain
HIGHFHGP_01699	1.25e-192	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HIGHFHGP_01700	4.52e-164	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HIGHFHGP_01701	0.0	pepO	3.4.24.11, 3.4.24.71	-	O	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase family M13
HIGHFHGP_01702	8.96e-150	ssb2	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
HIGHFHGP_01703	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIGHFHGP_01704	1.03e-197	-	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	Radical SAM superfamily
HIGHFHGP_01705	0.0	-	-	-	L	-	-	-	PIF1-like helicase
HIGHFHGP_01706	5.27e-154	orn	-	-	L	ko:K13288	ko03008,map03008	ko00000,ko00001,ko01000,ko03009,ko03019	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HIGHFHGP_01707	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HIGHFHGP_01708	2.04e-276	rfe	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 4
HIGHFHGP_01709	3.41e-152	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HIGHFHGP_01710	4.8e-159	livF	-	-	E	ko:K01995,ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01711	3.88e-205	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HIGHFHGP_01712	1.25e-240	-	-	-	U	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIGHFHGP_01713	1.08e-196	-	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HIGHFHGP_01714	4.61e-272	-	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HIGHFHGP_01715	1.26e-209	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIGHFHGP_01716	3.34e-246	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIGHFHGP_01717	6.44e-49	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HIGHFHGP_01719	3.29e-95	-	-	-	U	-	-	-	Drug resistance MFS transporter, drug H antiporter-2 family
HIGHFHGP_01720	4.15e-188	-	-	-	-	-	-	-	-
HIGHFHGP_01721	3.56e-94	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIGHFHGP_01722	4.06e-209	dkg	-	-	S	-	-	-	Oxidoreductase, aldo keto reductase family protein
HIGHFHGP_01723	9.34e-23	-	-	-	U	ko:K08168,ko:K18926	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
HIGHFHGP_01724	2.49e-111	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HIGHFHGP_01725	3.25e-223	glkA	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HIGHFHGP_01727	0.0	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HIGHFHGP_01729	3.91e-210	-	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
HIGHFHGP_01730	1.05e-87	fms	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HIGHFHGP_01731	3.52e-110	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HIGHFHGP_01732	2.07e-101	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HIGHFHGP_01733	3.05e-128	-	-	-	S	-	-	-	Prolyl oligopeptidase family
HIGHFHGP_01734	1.84e-119	-	-	-	C	-	-	-	Flavodoxin
HIGHFHGP_01735	9.48e-108	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HIGHFHGP_01736	3.1e-208	-	-	-	S	-	-	-	Aldo/keto reductase family
HIGHFHGP_01737	2.55e-105	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HIGHFHGP_01738	5.13e-07	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HIGHFHGP_01739	0.0	yjjK	-	-	S	-	-	-	ATP-binding cassette protein, ChvD family
HIGHFHGP_01740	9.98e-215	tesB	-	-	I	ko:K10805	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	Thioesterase-like superfamily
HIGHFHGP_01741	7.77e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF3180)
HIGHFHGP_01742	0.0	folK	2.7.6.3, 4.1.2.25	-	H	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIGHFHGP_01743	5.67e-200	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HIGHFHGP_01744	4.67e-154	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HIGHFHGP_01745	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIGHFHGP_01746	6.27e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HIGHFHGP_01747	1.31e-265	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K00760,ko:K04075	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIGHFHGP_01748	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HIGHFHGP_01749	0.0	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HIGHFHGP_01750	1.79e-226	natA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_01751	7.16e-298	-	-	-	M	-	-	-	Glycosyl transferase family 21
HIGHFHGP_01752	0.0	-	-	-	S	-	-	-	AI-2E family transporter
HIGHFHGP_01753	1.09e-226	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HIGHFHGP_01754	1.73e-270	fucO	1.1.1.77, 1.1.99.37, 1.2.98.1	-	C	ko:K00048,ko:K17067	ko00625,ko00630,ko00640,ko00680,ko01120,ko01200,map00625,map00630,map00640,map00680,map01120,map01200	ko00000,ko00001,ko01000	Iron-containing alcohol dehydrogenase
HIGHFHGP_01755	0.0	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	Mycolic acid cyclopropane synthetase
HIGHFHGP_01758	2.45e-215	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIGHFHGP_01761	1.19e-15	-	-	-	S	-	-	-	Helix-turn-helix domain
HIGHFHGP_01762	7.09e-263	-	-	-	S	-	-	-	Helix-turn-helix domain
HIGHFHGP_01763	1.11e-106	-	-	-	S	ko:K18955	-	ko00000,ko03000	Transcription factor WhiB
HIGHFHGP_01764	1.19e-128	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	AAA domain
HIGHFHGP_01765	7.39e-54	-	-	-	-	-	-	-	-
HIGHFHGP_01766	0.0	-	-	-	S	-	-	-	ATPases associated with a variety of cellular activities
HIGHFHGP_01767	2.17e-122	-	-	-	K	-	-	-	FR47-like protein
HIGHFHGP_01768	6.65e-152	-	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	haloacid dehalogenase-like hydrolase
HIGHFHGP_01769	0.0	-	-	-	D	-	-	-	Cell surface antigen C-terminus
HIGHFHGP_01772	5.4e-41	-	-	-	-	-	-	-	-
HIGHFHGP_01773	2.03e-188	-	-	-	-	-	-	-	-
HIGHFHGP_01774	1.77e-54	-	-	-	S	-	-	-	PrgI family protein
HIGHFHGP_01775	0.0	-	-	-	U	-	-	-	type IV secretory pathway VirB4
HIGHFHGP_01776	5.64e-256	-	-	-	M	-	-	-	CHAP domain
HIGHFHGP_01777	2.37e-211	-	-	-	-	-	-	-	-
HIGHFHGP_01778	5.18e-58	-	-	-	-	-	-	-	-
HIGHFHGP_01779	2.01e-183	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HIGHFHGP_01780	0.0	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	Type IV secretory system Conjugative DNA transfer
HIGHFHGP_01782	1.36e-62	-	-	-	-	-	-	-	-
HIGHFHGP_01783	1.84e-285	-	-	-	S	-	-	-	Antirestriction protein (ArdA)
HIGHFHGP_01784	1.83e-150	-	-	-	-	-	-	-	-
HIGHFHGP_01785	4.78e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3801)
HIGHFHGP_01786	0.0	-	-	-	U	-	-	-	Relaxase/Mobilisation nuclease domain
HIGHFHGP_01787	1.94e-91	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HIGHFHGP_01788	4.58e-82	-	-	-	-	-	-	-	-
HIGHFHGP_01789	1.57e-62	-	-	-	-	-	-	-	-
HIGHFHGP_01790	0.0	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	ParB-like nuclease domain
HIGHFHGP_01791	9.42e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF4192)
HIGHFHGP_01792	3.29e-101	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HIGHFHGP_01793	2.31e-230	intA	-	-	L	-	-	-	Phage integrase family
HIGHFHGP_01795	3.06e-17	-	-	-	L	-	-	-	Phage integrase family
HIGHFHGP_01796	0.0	gph	-	-	G	ko:K16209	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HIGHFHGP_01797	0.0	lacZ6	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01798	2.07e-236	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HIGHFHGP_01799	2.91e-28	-	-	-	L	-	-	-	Helix-turn-helix domain
HIGHFHGP_01800	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_01801	2.49e-276	-	-	-	GK	-	-	-	ROK family
HIGHFHGP_01802	2.2e-10	-	-	-	U	ko:K17330	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01803	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, domain 2
HIGHFHGP_01805	2.41e-286	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HIGHFHGP_01806	1.52e-267	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HIGHFHGP_01807	9.79e-143	vex	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_01808	8.98e-16	-	-	-	E	-	-	-	AzlC protein
HIGHFHGP_01809	3.01e-127	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	low molecular weight
HIGHFHGP_01810	2.52e-163	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	dihydrofolate reductase
HIGHFHGP_01811	1.73e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIGHFHGP_01812	1.85e-95	-	-	-	O	-	-	-	OsmC-like protein
HIGHFHGP_01813	2.73e-241	-	-	-	T	-	-	-	Universal stress protein family
HIGHFHGP_01814	2.97e-140	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HIGHFHGP_01815	5.88e-138	-	-	-	M	-	-	-	NlpC/P60 family
HIGHFHGP_01816	2.08e-216	-	-	-	S	-	-	-	CHAP domain
HIGHFHGP_01817	1.17e-270	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HIGHFHGP_01818	2.3e-44	-	-	-	-	-	-	-	-
HIGHFHGP_01819	1.77e-236	senX3	2.7.13.3	-	T	ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HIGHFHGP_01820	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HIGHFHGP_01821	3.9e-178	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HIGHFHGP_01822	1.37e-222	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HIGHFHGP_01823	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HIGHFHGP_01825	1.02e-280	-	-	-	EGP	ko:K08156,ko:K19577	-	ko00000,ko02000	Major Facilitator Superfamily
HIGHFHGP_01826	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4037)
HIGHFHGP_01827	6.18e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF4125)
HIGHFHGP_01828	0.0	-	-	-	S	ko:K06889	-	ko00000	alpha beta
HIGHFHGP_01829	5.51e-105	-	-	-	-	-	-	-	-
HIGHFHGP_01830	0.0	pspC	-	-	KT	-	-	-	PspC domain
HIGHFHGP_01831	2e-301	tcsS3	-	-	KT	-	-	-	PspC domain
HIGHFHGP_01832	1.01e-152	tcsR3	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HIGHFHGP_01833	4.59e-226	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HIGHFHGP_01834	2.82e-260	-	2.7.1.162	-	S	ko:K13059	-	ko00000,ko01000	Phosphotransferase enzyme family
HIGHFHGP_01835	0.0	gnpA	2.4.1.211	-	S	ko:K15533	-	ko00000,ko01000	Lacto-N-biose phosphorylase C-terminal domain
HIGHFHGP_01836	5.76e-217	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	ABC transporter permease
HIGHFHGP_01837	3.93e-223	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01838	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_01840	5.59e-308	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIGHFHGP_01841	1.32e-254	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HIGHFHGP_01842	1.85e-208	arbG	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HIGHFHGP_01843	0.0	ptsG	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system, glucose-specific IIABC component
HIGHFHGP_01844	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HIGHFHGP_01845	3.65e-251	-	-	-	S	-	-	-	Protein conserved in bacteria
HIGHFHGP_01846	8.64e-97	-	-	-	K	-	-	-	Transcriptional regulator
HIGHFHGP_01847	0.0	merA	1.16.1.1	-	C	ko:K00520,ko:K21739	-	ko00000,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HIGHFHGP_01848	2.04e-237	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIGHFHGP_01849	1.82e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HIGHFHGP_01850	5.05e-07	-	-	-	S	-	-	-	Mitochondrial domain of unknown function (DUF1713)
HIGHFHGP_01851	4.12e-133	-	-	-	-	-	-	-	-
HIGHFHGP_01852	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIGHFHGP_01853	8.69e-280	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin kinase
HIGHFHGP_01854	3.45e-271	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIGHFHGP_01855	3.5e-107	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIGHFHGP_01856	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIGHFHGP_01857	1.3e-242	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HIGHFHGP_01858	1.37e-162	-	-	-	-	-	-	-	-
HIGHFHGP_01859	1.08e-91	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_01861	3.06e-196	-	-	-	E	-	-	-	Transglutaminase/protease-like homologues
HIGHFHGP_01862	0.0	gcs2	-	-	S	ko:K06048	-	ko00000,ko01000	A circularly permuted ATPgrasp
HIGHFHGP_01863	2.99e-217	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIGHFHGP_01864	2.36e-90	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HIGHFHGP_01865	8.1e-236	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIGHFHGP_01866	7.34e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIGHFHGP_01867	2e-82	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIGHFHGP_01868	1.47e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HIGHFHGP_01869	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIGHFHGP_01870	2.57e-128	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIGHFHGP_01871	1.21e-315	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIGHFHGP_01872	1.07e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HIGHFHGP_01873	4.64e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30p/L7e
HIGHFHGP_01874	2.25e-129	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIGHFHGP_01875	1.26e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIGHFHGP_01876	3.14e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIGHFHGP_01877	3.17e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIGHFHGP_01878	7.06e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIGHFHGP_01879	1.95e-134	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIGHFHGP_01880	5.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIGHFHGP_01881	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIGHFHGP_01882	1.11e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIGHFHGP_01883	1.97e-49	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HIGHFHGP_01884	3.85e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIGHFHGP_01885	1.85e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIGHFHGP_01886	1.09e-74	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIGHFHGP_01887	1.4e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIGHFHGP_01888	3.85e-195	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIGHFHGP_01889	2.54e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIGHFHGP_01890	9.78e-151	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HIGHFHGP_01891	1.11e-149	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIGHFHGP_01892	9.35e-68	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HIGHFHGP_01893	1.09e-175	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HIGHFHGP_01894	3.3e-181	-	-	-	S	-	-	-	YwiC-like protein
HIGHFHGP_01895	0.0	adhE	1.1.1.1, 1.2.1.10, 1.2.1.81	-	C	ko:K04072,ko:K15515	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HIGHFHGP_01896	1.3e-284	-	-	-	GK	-	-	-	transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HIGHFHGP_01897	0.0	glgX	3.2.1.196, 3.2.1.68	CBM48,GH13	G	ko:K01214,ko:K02438	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 13 family
HIGHFHGP_01898	3.09e-12	-	-	-	L	-	-	-	Helix-turn-helix domain
HIGHFHGP_01899	9.6e-106	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HIGHFHGP_01900	5.33e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIGHFHGP_01901	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HIGHFHGP_01902	9.47e-152	-	-	-	-	-	-	-	-
HIGHFHGP_01903	6.88e-144	yigZ	-	-	S	-	-	-	Uncharacterized protein family UPF0029
HIGHFHGP_01904	1.17e-233	pdxB	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIGHFHGP_01905	2.6e-136	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein PGA_cap
HIGHFHGP_01906	1.16e-311	-	3.2.1.21	-	G	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
HIGHFHGP_01907	5.08e-205	-	-	-	U	ko:K02026,ko:K10190	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01908	4.88e-208	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01909	7.7e-312	-	-	-	G	ko:K02027,ko:K10227	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_01910	7.41e-277	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_01911	2.08e-30	-	-	-	-	-	-	-	-
HIGHFHGP_01913	2.99e-77	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HIGHFHGP_01914	4.87e-30	-	-	-	S	ko:K11939	-	ko00000,ko02000	EamA-like transporter family
HIGHFHGP_01915	3.49e-302	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIGHFHGP_01916	8.83e-286	dapC	-	-	E	-	-	-	Aminotransferase class I and II
HIGHFHGP_01917	4.51e-79	fdxA	-	-	C	ko:K05524	-	ko00000	4Fe-4S binding domain
HIGHFHGP_01918	0.0	-	-	-	E	ko:K03294	-	ko00000	aromatic amino acid transport protein AroP K03293
HIGHFHGP_01919	4.96e-289	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HIGHFHGP_01920	1.03e-34	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L33
HIGHFHGP_01924	1.73e-63	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIGHFHGP_01925	3.24e-184	-	-	-	-	-	-	-	-
HIGHFHGP_01926	2.1e-112	rimJ	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HIGHFHGP_01927	2.06e-78	ygfA	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	5-formyltetrahydrofolate cyclo-ligase family
HIGHFHGP_01928	6.24e-43	-	-	-	S	-	-	-	Putative regulatory protein
HIGHFHGP_01929	7.67e-135	-	-	-	NO	-	-	-	SAF
HIGHFHGP_01930	8.07e-34	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HIGHFHGP_01931	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases and helicase subunits
HIGHFHGP_01932	1.79e-282	-	-	-	T	-	-	-	Forkhead associated domain
HIGHFHGP_01933	1.06e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIGHFHGP_01934	2.41e-113	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIGHFHGP_01935	2.92e-188	-	-	-	S	-	-	-	alpha beta
HIGHFHGP_01936	0.0	-	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HIGHFHGP_01937	4.51e-190	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIGHFHGP_01938	2.64e-221	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HIGHFHGP_01939	6.67e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HIGHFHGP_01940	2.32e-260	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import
HIGHFHGP_01941	1.5e-182	regX3	-	-	KT	ko:K07776	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HIGHFHGP_01942	9e-279	phoR	2.7.13.3	-	T	ko:K07636,ko:K07768	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HIGHFHGP_01943	1.75e-300	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HIGHFHGP_01944	1.48e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIGHFHGP_01945	9.45e-300	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HIGHFHGP_01946	1.62e-277	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HIGHFHGP_01947	1.19e-112	-	-	-	G	ko:K12112	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001	YhcH YjgK YiaL family protein
HIGHFHGP_01948	0.0	-	3.2.1.23	-	G	ko:K12111	ko00052,ko00511,ko01100,map00052,map00511,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.87
HIGHFHGP_01949	4.32e-147	pgmB	5.4.2.6	-	S	ko:K01838,ko:K04844	ko00500,map00500	ko00000,ko00001,ko01000	phosphonoacetaldehyde hydrolase activity
HIGHFHGP_01950	4.43e-198	-	-	-	EG	-	-	-	EamA-like transporter family
HIGHFHGP_01951	0.0	kojP	2.4.1.230, 2.4.1.64	GH65	G	ko:K05342,ko:K10231	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HIGHFHGP_01952	7.49e-196	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01953	7.01e-217	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_01954	1.18e-302	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_01955	4.36e-239	-	-	-	K	-	-	-	Periplasmic binding protein domain
HIGHFHGP_01956	3.47e-128	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HIGHFHGP_01957	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HIGHFHGP_01958	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HIGHFHGP_01959	9.81e-120	-	-	-	D	-	-	-	nuclear chromosome segregation
HIGHFHGP_01960	6.14e-162	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIGHFHGP_01961	3.28e-194	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HIGHFHGP_01962	2.13e-254	yfiH	-	-	Q	ko:K05810	-	ko00000,ko01000	Multi-copper polyphenol oxidoreductase laccase
HIGHFHGP_01963	0.0	-	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase family U32 C-terminal domain
HIGHFHGP_01964	9.7e-225	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HIGHFHGP_01965	1.93e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Conserved hypothetical protein 95
HIGHFHGP_01966	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	helicase superfamily c-terminal domain
HIGHFHGP_01967	1.05e-40	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L28 family
HIGHFHGP_01968	2.1e-246	-	-	-	G	-	-	-	pfkB family carbohydrate kinase
HIGHFHGP_01969	3.16e-296	-	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HIGHFHGP_01970	4.42e-166	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HIGHFHGP_01971	1.75e-87	-	-	-	T	-	-	-	Toxic component of a toxin-antitoxin (TA) module
HIGHFHGP_01972	7.21e-72	-	-	-	L	-	-	-	RelB antitoxin
HIGHFHGP_01973	2.78e-33	yxiO	-	-	G	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Major facilitator Superfamily
HIGHFHGP_01974	3.47e-245	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIGHFHGP_01975	3.06e-82	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HIGHFHGP_01979	2.03e-58	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HIGHFHGP_01981	0.0	pccB	-	-	I	-	-	-	Carboxyl transferase domain
HIGHFHGP_01982	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HIGHFHGP_01984	3.92e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HIGHFHGP_01985	7.03e-190	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Biotin/lipoate A/B protein ligase family
HIGHFHGP_01986	0.0	-	-	-	-	-	-	-	-
HIGHFHGP_01987	3.74e-211	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HIGHFHGP_01988	1.01e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIGHFHGP_01989	7.11e-96	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIGHFHGP_01990	1.29e-172	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HIGHFHGP_01991	5.79e-43	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIGHFHGP_01993	1.37e-292	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K08969,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	DegT/DnrJ/EryC1/StrS aminotransferase family
HIGHFHGP_01994	2.27e-287	-	-	-	G	-	-	-	polysaccharide deacetylase
HIGHFHGP_01995	1.45e-247	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIGHFHGP_01996	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIGHFHGP_01997	1.44e-51	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal L27 protein
HIGHFHGP_01998	1.01e-62	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HIGHFHGP_01999	0.0	rne	3.1.26.12	-	J	ko:K08300,ko:K08301	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	Ribonuclease E/G family
HIGHFHGP_02000	8.53e-294	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
HIGHFHGP_02001	1.58e-213	-	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HIGHFHGP_02002	6.01e-214	-	4.1.2.28	-	EM	ko:K22397	ko00040,map00040	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
HIGHFHGP_02003	1.15e-190	-	-	-	S	ko:K07046	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Amidohydrolase
HIGHFHGP_02004	1.93e-270	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HIGHFHGP_02005	5.27e-191	-	1.1.1.100, 1.1.1.413	-	IQ	ko:K00059,ko:K18333,ko:K22322	ko00051,ko00061,ko00333,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,map00051,map00061,map00333,map00780,map01040,map01100,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
HIGHFHGP_02006	0.0	-	4.2.1.68	-	M	ko:K18334	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Enolase C-terminal domain-like
HIGHFHGP_02007	4.75e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
HIGHFHGP_02008	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HIGHFHGP_02009	8.7e-178	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_02010	3.47e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF1778)
HIGHFHGP_02011	4.05e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HIGHFHGP_02012	0.0	maf	-	-	DF	ko:K06287	-	ko00000	Maf-like protein
HIGHFHGP_02013	7.94e-232	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIGHFHGP_02014	1.59e-303	hom	1.1.1.3, 2.7.2.4	-	E	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HIGHFHGP_02015	2.02e-65	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HIGHFHGP_02016	1.26e-71	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HIGHFHGP_02017	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIGHFHGP_02018	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HIGHFHGP_02019	4.31e-167	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HIGHFHGP_02020	4.89e-283	-	-	-	G	-	-	-	Transmembrane secretion effector
HIGHFHGP_02021	0.0	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIGHFHGP_02022	0.0	nox	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HIGHFHGP_02023	7.5e-201	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HIGHFHGP_02024	2.47e-154	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02025	5.39e-179	-	-	-	P	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02026	3.53e-134	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
HIGHFHGP_02027	4.6e-169	-	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_02028	4.34e-282	pyr	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroorotate dehydrogenase
HIGHFHGP_02029	6.68e-27	-	-	-	T	-	-	-	Histidine kinase
HIGHFHGP_02030	3.22e-17	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
HIGHFHGP_02031	6.62e-171	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIGHFHGP_02032	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIGHFHGP_02033	5.82e-182	ltbR	-	-	K	-	-	-	Transcriptional regulator, IclR family, C-terminal domain protein
HIGHFHGP_02034	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HIGHFHGP_02035	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HIGHFHGP_02036	8.83e-317	mutT	3.6.1.55	-	LT	ko:K03574	-	ko00000,ko01000,ko03400	Phosphoglycerate mutase family
HIGHFHGP_02037	3.3e-174	-	-	-	-	-	-	-	-
HIGHFHGP_02038	0.0	-	-	-	G	-	-	-	N-terminal domain of (some) glycogen debranching enzymes
HIGHFHGP_02039	1.73e-177	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02040	1.3e-267	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02041	6.84e-264	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_02042	1.2e-164	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_02043	9.47e-151	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIGHFHGP_02044	1.05e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIGHFHGP_02045	2.2e-275	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HIGHFHGP_02046	9.69e-277	gluQ	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HIGHFHGP_02048	0.0	clpB	-	-	O	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HIGHFHGP_02049	2.32e-208	-	-	-	S	ko:K07088	-	ko00000	Auxin Efflux Carrier
HIGHFHGP_02050	4.2e-202	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
HIGHFHGP_02051	5.17e-162	-	-	-	S	-	-	-	Domain of unknown function (DUF4190)
HIGHFHGP_02052	4.44e-223	-	-	-	-	-	-	-	-
HIGHFHGP_02053	5.41e-299	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HIGHFHGP_02054	1.5e-256	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HIGHFHGP_02055	2.67e-308	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
HIGHFHGP_02056	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HIGHFHGP_02057	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.26
HIGHFHGP_02058	0.0	lsgC	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HIGHFHGP_02059	1.47e-298	-	-	-	GM	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_02060	2.9e-192	tagG	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HIGHFHGP_02061	0.0	-	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
HIGHFHGP_02062	1.54e-232	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HIGHFHGP_02063	1e-217	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIGHFHGP_02064	0.0	rfbD	1.1.1.133, 5.1.3.13	-	M	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIGHFHGP_02065	7.18e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIGHFHGP_02066	0.0	-	-	-	-	-	-	-	-
HIGHFHGP_02067	4.97e-221	-	-	-	M	-	-	-	Glycosyl transferase family 2
HIGHFHGP_02068	2.58e-301	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HIGHFHGP_02069	8.52e-305	yvhJ	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HIGHFHGP_02070	0.0	-	-	-	V	-	-	-	ABC transporter permease
HIGHFHGP_02071	3.4e-246	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HIGHFHGP_02072	1.4e-186	-	-	-	T	ko:K06950	-	ko00000	HD domain
HIGHFHGP_02073	2.46e-205	-	-	-	S	-	-	-	Glutamine amidotransferase domain
HIGHFHGP_02074	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HIGHFHGP_02075	1.35e-237	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	TatD related DNase
HIGHFHGP_02076	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HIGHFHGP_02077	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HIGHFHGP_02078	0.0	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HIGHFHGP_02079	8.8e-55	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HIGHFHGP_02080	3.65e-189	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HIGHFHGP_02081	2.58e-105	-	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HIGHFHGP_02082	7.04e-63	-	-	-	-	-	-	-	-
HIGHFHGP_02083	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIGHFHGP_02084	5.33e-156	-	-	-	-	-	-	-	-
HIGHFHGP_02085	7.8e-238	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIGHFHGP_02087	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
HIGHFHGP_02088	3.69e-232	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HIGHFHGP_02089	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter transmembrane region
HIGHFHGP_02090	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HIGHFHGP_02091	8.11e-121	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HIGHFHGP_02092	0.0	-	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HIGHFHGP_02093	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HIGHFHGP_02094	1.76e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HIGHFHGP_02095	7.06e-132	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HIGHFHGP_02096	0.0	aroP	-	-	E	ko:K03293,ko:K11732	-	ko00000,ko02000	aromatic amino acid transport protein AroP K03293
HIGHFHGP_02097	1.15e-136	-	-	-	S	-	-	-	Protein of unknown function, DUF624
HIGHFHGP_02098	4.49e-196	-	-	-	G	ko:K02026,ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HIGHFHGP_02099	1.34e-199	msmF	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02100	2.22e-234	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HIGHFHGP_02101	0.0	amyE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_02102	1.29e-132	gpm2	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HIGHFHGP_02103	6.43e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF4235)
HIGHFHGP_02104	1.05e-177	nfrA	-	-	C	-	-	-	Nitroreductase family
HIGHFHGP_02105	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HIGHFHGP_02106	0.0	-	-	-	S	ko:K01421	-	ko00000	YhgE Pip domain protein
HIGHFHGP_02107	6.32e-55	-	-	-	-	-	-	-	-
HIGHFHGP_02109	2.92e-182	cobB2	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
HIGHFHGP_02110	7.76e-294	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HIGHFHGP_02111	0.0	-	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HIGHFHGP_02112	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HIGHFHGP_02113	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha-amylase domain
HIGHFHGP_02114	5.86e-189	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02115	4.77e-247	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02116	0.0	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_02117	1.26e-296	-	-	-	G	-	-	-	Protein of unknown function (DUF2961)
HIGHFHGP_02118	7.93e-306	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_02119	1.36e-244	-	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HIGHFHGP_02120	2e-240	-	-	-	K	-	-	-	Periplasmic binding protein-like domain
HIGHFHGP_02121	2.05e-196	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02122	3.84e-208	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HIGHFHGP_02123	9.35e-312	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HIGHFHGP_02124	2.68e-295	-	-	-	GK	-	-	-	ROK family
HIGHFHGP_02125	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Glycosyl hydrolase family 36 N-terminal domain
HIGHFHGP_02126	4.34e-103	tadA	3.5.4.1, 3.5.4.33	-	FJ	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIGHFHGP_02127	0.0	nhaP	-	-	P	ko:K03316	-	ko00000	Sodium/hydrogen exchanger family
HIGHFHGP_02128	1.77e-159	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HIGHFHGP_02129	1.2e-186	-	-	-	S	ko:K06999	-	ko00000	Phospholipase/Carboxylesterase
HIGHFHGP_02130	3.67e-195	-	-	-	-	-	-	-	-
HIGHFHGP_02131	6.04e-144	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dCTP deaminase family
HIGHFHGP_02132	9.17e-132	-	-	-	-	-	-	-	-
HIGHFHGP_02133	0.0	pacL2	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HIGHFHGP_02134	1.55e-20	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_02135	1.3e-111	-	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HIGHFHGP_02136	0.0	nagE	2.7.1.193	-	G	ko:K02802,ko:K02803,ko:K02804	ko00520,ko02060,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HIGHFHGP_02137	2.78e-273	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HIGHFHGP_02138	2.26e-222	rlmB	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIGHFHGP_02139	5.37e-216	-	5.1.3.15	-	G	ko:K01792	ko00010,ko01100,ko01110,ko01120,ko01130,map00010,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Aldose 1-epimerase
HIGHFHGP_02140	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HIGHFHGP_02141	0.0	-	-	-	KLT	-	-	-	Domain of unknown function (DUF4032)
HIGHFHGP_02142	4.31e-197	-	-	-	-	-	-	-	-
HIGHFHGP_02143	2.77e-18	tnp3521a2	-	-	L	-	-	-	Integrase core domain
HIGHFHGP_02144	7.94e-167	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HIGHFHGP_02145	3.27e-186	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HIGHFHGP_02146	5.52e-223	rbsA	3.6.3.17	-	G	ko:K10441,ko:K10542,ko:K17215	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HIGHFHGP_02147	6.14e-191	-	-	-	U	ko:K10439,ko:K10440	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HIGHFHGP_02148	3.33e-232	-	-	-	-	-	-	-	-
HIGHFHGP_02150	2.62e-27	-	-	-	L	-	-	-	Winged helix-turn helix
HIGHFHGP_02151	7.62e-270	ugpC	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HIGHFHGP_02152	1.02e-175	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA domain
HIGHFHGP_02153	1.55e-307	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HIGHFHGP_02154	3.61e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HIGHFHGP_02155	3.21e-93	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HIGHFHGP_02156	2.04e-275	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HIGHFHGP_02157	1.26e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIGHFHGP_02159	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIGHFHGP_02160	8.2e-113	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HIGHFHGP_02161	1.62e-57	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HIGHFHGP_02162	6.17e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HIGHFHGP_02163	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 N-terminal domain protein
HIGHFHGP_02164	3.18e-155	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HIGHFHGP_02165	2.5e-162	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
HIGHFHGP_02166	5.67e-16	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HIGHFHGP_02167	1.36e-79	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HIGHFHGP_02168	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HIGHFHGP_02169	1.31e-165	-	-	-	T	-	-	-	GHKL domain
HIGHFHGP_02170	4.57e-152	-	-	-	T	-	-	-	LytTr DNA-binding domain
HIGHFHGP_02171	1.36e-90	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HIGHFHGP_02172	0.0	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HIGHFHGP_02173	1.79e-181	-	-	-	O	-	-	-	Thioredoxin
HIGHFHGP_02175	7e-281	rpfB	-	-	S	ko:K21688	-	ko00000	G5
HIGHFHGP_02176	1.31e-214	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIGHFHGP_02177	1.49e-223	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HIGHFHGP_02178	4.16e-143	-	-	-	S	-	-	-	LytR cell envelope-related transcriptional attenuator
HIGHFHGP_02179	0.0	pcnA	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Probable RNA and SrmB- binding site of polymerase A
HIGHFHGP_02180	2.5e-209	mutT4	-	-	L	-	-	-	Belongs to the Nudix hydrolase family
HIGHFHGP_02181	0.0	-	-	-	-	-	-	-	-
HIGHFHGP_02182	0.0	mviN	-	-	KLT	ko:K03980	-	ko00000,ko01011,ko02000	MviN-like protein
HIGHFHGP_02183	3.49e-155	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIGHFHGP_02184	7.93e-45	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIGHFHGP_02185	9.54e-285	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HIGHFHGP_02186	5.17e-223	parA	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HIGHFHGP_02187	3.05e-160	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HIGHFHGP_02188	1.14e-118	jag	-	-	S	ko:K06346	-	ko00000	Putative single-stranded nucleic acids-binding domain
HIGHFHGP_02189	1.07e-238	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Membrane protein insertase, YidC Oxa1 family
HIGHFHGP_02190	2.07e-73	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HIGHFHGP_02191	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family