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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKCAJAIO_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKCAJAIO_00002	1.29e-258	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKCAJAIO_00003	1.4e-40	yyzM	-	-	S	-	-	-	Protein conserved in bacteria
HKCAJAIO_00004	3.04e-258	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKCAJAIO_00005	4.43e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKCAJAIO_00006	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKCAJAIO_00007	3.77e-53	yabO	-	-	J	-	-	-	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HKCAJAIO_00008	1.16e-80	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKCAJAIO_00009	1.94e-05	-	-	-	-	-	-	-	-
HKCAJAIO_00010	2.66e-307	-	3.5.2.6	-	V	ko:K01467	ko01501,ko02020,map01501,map02020	ko00000,ko00001,ko00002,ko01000	Beta-lactamase enzyme family
HKCAJAIO_00011	3.77e-307	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKCAJAIO_00012	2.22e-126	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKCAJAIO_00013	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKCAJAIO_00014	1.3e-209	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00015	1.39e-119	-	-	-	L	-	-	-	Transposase
HKCAJAIO_00016	7.11e-39	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_00017	8e-106	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_00033	4.24e-183	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKCAJAIO_00034	1.34e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HKCAJAIO_00035	3.54e-175	pcsB	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
HKCAJAIO_00036	2.75e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKCAJAIO_00037	1.06e-278	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKCAJAIO_00038	5.05e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKCAJAIO_00039	2.58e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKCAJAIO_00040	3.89e-46	acpP_1	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKCAJAIO_00041	1.75e-166	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKCAJAIO_00042	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKCAJAIO_00043	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKCAJAIO_00044	5.98e-242	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKCAJAIO_00045	6.85e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKCAJAIO_00046	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKCAJAIO_00047	1.7e-117	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_00048	4.39e-66	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_00049	1.37e-41	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_00050	6.22e-207	-	-	-	S	-	-	-	CHAP domain
HKCAJAIO_00051	1.65e-305	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKCAJAIO_00052	2.66e-99	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKCAJAIO_00053	1.03e-261	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKCAJAIO_00054	1.69e-181	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Ketopantoate reductase
HKCAJAIO_00055	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKCAJAIO_00056	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HKCAJAIO_00057	1.36e-90	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKCAJAIO_00058	5.42e-75	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HKCAJAIO_00059	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKCAJAIO_00060	1.06e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKCAJAIO_00061	2.17e-81	-	-	-	KT	-	-	-	phosphorelay signal transduction system
HKCAJAIO_00063	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKCAJAIO_00065	4.38e-134	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKCAJAIO_00066	1.89e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	3-methyladenine DNA glycosylase
HKCAJAIO_00067	2.06e-296	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKCAJAIO_00068	2.51e-261	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKCAJAIO_00069	1.27e-86	spxA_2	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HKCAJAIO_00084	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKCAJAIO_00085	4.87e-299	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HKCAJAIO_00086	4.88e-49	XK27_02060	-	-	S	-	-	-	Transglycosylase associated protein
HKCAJAIO_00087	1.44e-72	badR	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HKCAJAIO_00088	1.29e-106	XK27_03570	-	-	S	ko:K19784	-	ko00000	reductase
HKCAJAIO_00089	3.79e-116	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_00090	1.2e-54	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_00092	1.88e-99	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	carboxypeptidase activity
HKCAJAIO_00093	1.28e-102	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HKCAJAIO_00096	2.48e-176	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKCAJAIO_00097	1.73e-232	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKCAJAIO_00098	3.55e-109	-	-	-	S	-	-	-	Putative small multi-drug export protein
HKCAJAIO_00099	2.83e-99	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HKCAJAIO_00100	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HKCAJAIO_00101	1.71e-193	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKCAJAIO_00102	3.96e-40	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKCAJAIO_00103	3.26e-294	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKCAJAIO_00104	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKCAJAIO_00105	1.9e-185	-	-	-	S	-	-	-	SseB protein N-terminal domain
HKCAJAIO_00106	7.75e-145	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
HKCAJAIO_00107	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKCAJAIO_00108	2.1e-90	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKCAJAIO_00111	1.23e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKCAJAIO_00112	8.14e-120	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HKCAJAIO_00113	1.1e-199	yitS	-	-	S	-	-	-	DegV family
HKCAJAIO_00114	1.29e-05	-	-	-	K	-	-	-	PFAM helix-turn-helix domain protein
HKCAJAIO_00115	1.22e-42	-	-	-	K	-	-	-	helix-turn-helix
HKCAJAIO_00116	4e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKCAJAIO_00117	7.02e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKCAJAIO_00118	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKCAJAIO_00119	1.8e-308	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00120	5.98e-47	-	-	-	K	-	-	-	sequence-specific DNA binding
HKCAJAIO_00122	0.0	-	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
HKCAJAIO_00123	8.01e-295	spaC2	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C family protein
HKCAJAIO_00124	3.69e-236	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKCAJAIO_00125	5.31e-120	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Divergent AAA domain protein
HKCAJAIO_00126	1.88e-63	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKCAJAIO_00127	3.54e-132	int	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKCAJAIO_00128	1.43e-52	-	-	-	S	-	-	-	Helix-turn-helix domain
HKCAJAIO_00129	1.37e-219	-	-	-	-	-	-	-	-
HKCAJAIO_00131	4.04e-95	isp2	-	-	S	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	pathogenesis
HKCAJAIO_00132	3.78e-117	-	-	-	L	ko:K07498	-	ko00000	Transposase
HKCAJAIO_00133	3.89e-285	capA	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
HKCAJAIO_00134	1.76e-52	XK27_08630	-	-	T	ko:K07166	-	ko00000	UPF0237 protein
HKCAJAIO_00135	1.6e-307	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKCAJAIO_00136	1.93e-49	ais	-	-	G	-	-	-	alpha-ribazole phosphatase activity
HKCAJAIO_00137	7.71e-185	yodJ	3.4.16.4, 3.4.17.14	-	M	ko:K01286,ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HKCAJAIO_00138	7.28e-132	acmA	3.2.1.17	-	NU	ko:K01185,ko:K02395	-	ko00000,ko01000,ko02035	amidase activity
HKCAJAIO_00139	2.19e-250	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKCAJAIO_00140	2.58e-101	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKCAJAIO_00141	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKCAJAIO_00142	4.64e-253	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKCAJAIO_00143	7.15e-177	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKCAJAIO_00144	3.02e-176	thiD	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	phosphomethylpyrimidine kinase
HKCAJAIO_00145	9.65e-96	hmpT	-	-	S	-	-	-	cog cog4720
HKCAJAIO_00149	4.51e-66	amd	-	-	E	-	-	-	Peptidase dimerisation domain
HKCAJAIO_00150	1.13e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKCAJAIO_00151	1.22e-113	-	-	-	-	-	-	-	-
HKCAJAIO_00152	7.24e-102	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	DNA-templated transcription, initiation
HKCAJAIO_00153	5.87e-192	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKCAJAIO_00154	6.47e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKCAJAIO_00155	3.71e-119	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKCAJAIO_00156	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKCAJAIO_00157	3.04e-110	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
HKCAJAIO_00158	1.08e-106	-	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKCAJAIO_00159	4.45e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKCAJAIO_00160	7.42e-174	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKCAJAIO_00161	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKCAJAIO_00162	3.73e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HKCAJAIO_00163	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKCAJAIO_00164	4.95e-98	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKCAJAIO_00165	3.09e-13	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
HKCAJAIO_00166	1.69e-32	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
HKCAJAIO_00167	5.22e-69	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
HKCAJAIO_00168	7.68e-65	dex	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 66
HKCAJAIO_00169	9.52e-303	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKCAJAIO_00170	2.96e-145	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKCAJAIO_00171	4e-147	-	-	-	K	-	-	-	Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HKCAJAIO_00172	2.59e-258	XK27_00055	-	-	P	-	-	-	Major Facilitator
HKCAJAIO_00173	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKCAJAIO_00174	8.47e-126	-	-	-	V	-	-	-	VanZ like family
HKCAJAIO_00175	7.59e-10	-	-	-	D	-	-	-	nuclear chromosome segregation
HKCAJAIO_00177	3e-168	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00178	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKCAJAIO_00179	1.24e-195	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKCAJAIO_00180	4.29e-174	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKCAJAIO_00181	1.25e-248	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HKCAJAIO_00182	1.82e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HKCAJAIO_00183	5.93e-299	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HKCAJAIO_00184	2.95e-303	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKCAJAIO_00185	2.78e-98	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKCAJAIO_00186	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HKCAJAIO_00187	5.77e-13	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKCAJAIO_00188	1.34e-178	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKCAJAIO_00189	9e-36	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKCAJAIO_00190	4.03e-14	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKCAJAIO_00191	4.52e-54	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKCAJAIO_00192	3.42e-50	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKCAJAIO_00193	9.63e-38	oppD	-	-	P	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_00194	1.15e-43	oppD	-	-	P	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_00195	1.53e-82	-	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_00196	9.86e-54	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_00197	1.75e-78	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_00198	2.62e-85	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_00199	1.32e-29	-	-	-	-	-	-	-	-
HKCAJAIO_00200	3.85e-201	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKCAJAIO_00201	2.41e-234	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKCAJAIO_00202	1.03e-284	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKCAJAIO_00203	1.28e-94	adcR	-	-	K	-	-	-	transcriptional
HKCAJAIO_00204	8.76e-176	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKCAJAIO_00205	1.73e-163	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_00206	1.19e-207	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HKCAJAIO_00207	3.56e-86	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HKCAJAIO_00208	1.42e-197	ptsG	2.7.1.208	-	G	ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HKCAJAIO_00209	1.13e-136	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKCAJAIO_00210	2e-201	rgfB	3.1.3.90	-	L	ko:K06896	ko00500,map00500	ko00000,ko00001,ko01000	Endonuclease/Exonuclease/phosphatase family
HKCAJAIO_00211	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKCAJAIO_00212	3.92e-163	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HKCAJAIO_00213	9.27e-66	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein transport
HKCAJAIO_00214	1.76e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKCAJAIO_00215	1.83e-187	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKCAJAIO_00216	2.21e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKCAJAIO_00217	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKCAJAIO_00218	0.0	XK27_00665	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HKCAJAIO_00219	8.63e-183	cmpC	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_00220	6.35e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKCAJAIO_00221	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKCAJAIO_00222	3.93e-49	-	-	-	L	-	-	-	Transposase
HKCAJAIO_00223	2.46e-24	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_00224	4.56e-40	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_00227	1.16e-57	-	-	-	-	-	-	-	-
HKCAJAIO_00228	5.62e-75	WQ51_06355	-	-	S	-	-	-	TM2 domain
HKCAJAIO_00229	1.17e-212	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKCAJAIO_00230	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKCAJAIO_00231	4.01e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKCAJAIO_00232	6.28e-35	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Belongs to the SecE SEC61-gamma family
HKCAJAIO_00233	2.8e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKCAJAIO_00234	1.17e-110	-	3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27	-	I	ko:K01096,ko:K19302	ko00550,ko00564,ko01100,map00550,map00564,map01100	ko00000,ko00001,ko01000,ko01011	phosphatidate phosphatase activity
HKCAJAIO_00235	6.76e-73	cof	-	-	Q	-	-	-	phosphatase activity
HKCAJAIO_00236	1.89e-47	cof	-	-	Q	-	-	-	phosphatase activity
HKCAJAIO_00237	6.57e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	transcriptional regulator (DeoR family)
HKCAJAIO_00238	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKCAJAIO_00239	7.03e-53	napB	-	-	K	-	-	-	transcriptional
HKCAJAIO_00240	7.76e-30	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKCAJAIO_00241	3.44e-83	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKCAJAIO_00242	2.7e-84	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKCAJAIO_00243	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKCAJAIO_00244	6.15e-195	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKCAJAIO_00245	1.37e-99	yhaI	-	-	L	-	-	-	Membrane
HKCAJAIO_00246	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKCAJAIO_00247	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKCAJAIO_00248	1.72e-141	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKCAJAIO_00249	8.82e-124	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKCAJAIO_00250	3.39e-67	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKCAJAIO_00251	6.16e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKCAJAIO_00252	0.0	mapZ	-	-	D	ko:K20073	-	ko00000	Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HKCAJAIO_00253	0.0	snf	-	-	L	-	-	-	Superfamily II DNA RNA helicases, SNF2 family'
HKCAJAIO_00254	3.69e-27	XK27_11680	-	-	-	-	-	-	-
HKCAJAIO_00255	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKCAJAIO_00256	1.24e-104	XK27_09675	-	-	K	ko:K07105	-	ko00000	-acetyltransferase
HKCAJAIO_00257	0.0	mltG	-	-	ADL	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKCAJAIO_00258	1.17e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKCAJAIO_00259	3.41e-78	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_00260	1.52e-211	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKCAJAIO_00261	3.32e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKCAJAIO_00262	6.83e-169	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKCAJAIO_00263	1.86e-114	XK27_09705	-	-	S	ko:K06950	-	ko00000	HD superfamily hydrolase
HKCAJAIO_00264	2e-144	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKCAJAIO_00267	1.42e-310	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKCAJAIO_00268	2.12e-119	-	-	-	K	-	-	-	transcriptional regulator
HKCAJAIO_00269	5.74e-48	-	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HKCAJAIO_00270	1.89e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKCAJAIO_00271	1.64e-236	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKCAJAIO_00272	7.82e-128	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HKCAJAIO_00273	1.74e-111	ykuL	-	-	S	-	-	-	CBS domain
HKCAJAIO_00274	3.26e-172	xerD	-	-	L	-	-	-	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HKCAJAIO_00275	5.32e-153	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKCAJAIO_00276	7.56e-129	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKCAJAIO_00277	1.82e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKCAJAIO_00278	7.39e-54	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKCAJAIO_00279	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Cation transport protein
HKCAJAIO_00280	1.1e-311	trkA	-	-	P	ko:K03499	-	ko00000,ko02000	Potassium transporter peripheral membrane component
HKCAJAIO_00281	3.83e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKCAJAIO_00282	3.25e-116	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKCAJAIO_00283	2.31e-148	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Membrane-associated phospholipid phosphatase
HKCAJAIO_00284	1.03e-206	-	-	-	K	ko:K20342,ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HKCAJAIO_00285	5.6e-45	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
HKCAJAIO_00286	4.54e-47	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKCAJAIO_00287	3.47e-78	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKCAJAIO_00288	4.79e-47	-	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
HKCAJAIO_00289	2.72e-36	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	protein secretion by the type I secretion system
HKCAJAIO_00290	1.34e-89	comA	-	-	V	ko:K06147,ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKCAJAIO_00291	3.67e-62	yhaI	-	-	L	-	-	-	Membrane
HKCAJAIO_00292	8.86e-69	-	-	-	S	-	-	-	Domain of unknown function (DUF4173)
HKCAJAIO_00293	6.21e-124	ureI	-	-	S	ko:K03191	ko05120,map05120	ko00000,ko00001,ko02000	AmiS/UreI family transporter
HKCAJAIO_00294	1.02e-61	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HKCAJAIO_00295	3.78e-72	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HKCAJAIO_00296	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HKCAJAIO_00297	2.74e-101	ureE	-	-	O	ko:K03187	-	ko00000	enzyme active site formation
HKCAJAIO_00298	1.83e-169	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HKCAJAIO_00299	4.71e-142	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HKCAJAIO_00300	3.46e-204	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HKCAJAIO_00301	5e-227	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HKCAJAIO_00302	8.28e-177	nikQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport protein
HKCAJAIO_00303	4.48e-170	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKCAJAIO_00304	1.5e-195	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	amino acid transport
HKCAJAIO_00305	0.0	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKCAJAIO_00306	0.0	-	-	-	F	-	-	-	NUDIX domain
HKCAJAIO_00307	7.28e-268	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HKCAJAIO_00308	7.14e-194	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	amino acid transport
HKCAJAIO_00309	1.26e-212	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HKCAJAIO_00310	6.08e-112	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HKCAJAIO_00311	1.48e-82	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase activity
HKCAJAIO_00312	1.96e-82	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase activity
HKCAJAIO_00313	2.17e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKCAJAIO_00314	1.25e-143	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_00315	7.28e-268	sstT	-	-	E	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HKCAJAIO_00316	5.95e-202	ilvH	-	-	S	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
HKCAJAIO_00317	5.41e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HKCAJAIO_00318	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00319	3.54e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKCAJAIO_00320	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKCAJAIO_00321	4.58e-15	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-ascorbate 6-phosphate lactonase
HKCAJAIO_00322	1.98e-157	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HKCAJAIO_00323	1.28e-308	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	COG0168 Trk-type K transport systems, membrane components
HKCAJAIO_00324	1.5e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Ribosomal RNA small subunit methyltransferase G
HKCAJAIO_00325	1.14e-118	ylbN	-	-	K	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HKCAJAIO_00326	2.69e-158	csrR	-	-	T	-	-	-	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKCAJAIO_00327	0.0	covS	-	-	T	-	-	-	Histidine kinase
HKCAJAIO_00328	1.74e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKCAJAIO_00329	4.48e-277	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HKCAJAIO_00330	1.26e-212	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKCAJAIO_00331	5.05e-315	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKCAJAIO_00333	1.99e-45	-	-	-	-	-	-	-	-
HKCAJAIO_00334	3.37e-19	yrdC	-	-	Q	-	-	-	isochorismatase
HKCAJAIO_00335	3.94e-35	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_00336	1.13e-66	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_00337	6.11e-31	-	-	-	L	-	-	-	Transposase
HKCAJAIO_00338	1.92e-38	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_00339	2.31e-306	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKCAJAIO_00340	1.52e-81	manO	-	-	S	-	-	-	protein conserved in bacteria
HKCAJAIO_00341	8.21e-215	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
HKCAJAIO_00342	2.08e-162	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	pts system
HKCAJAIO_00343	3.98e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HKCAJAIO_00344	1.84e-181	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Metal-dependent hydrolase
HKCAJAIO_00345	1.46e-196	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HKCAJAIO_00346	5.45e-315	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKCAJAIO_00347	1.54e-101	ydiB	-	-	M	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HKCAJAIO_00348	6.67e-120	-	-	-	M	-	-	-	Acetyltransferase GNAT Family
HKCAJAIO_00349	1.29e-280	brpA	-	-	K	-	-	-	Transcriptional
HKCAJAIO_00350	3.06e-105	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKCAJAIO_00351	2.28e-270	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKCAJAIO_00352	6.68e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Nucleic-acid-binding protein implicated in transcription termination
HKCAJAIO_00353	2.19e-56	ylxQ	-	-	J	-	-	-	ribosomal protein
HKCAJAIO_00354	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKCAJAIO_00355	9.81e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKCAJAIO_00356	1.44e-29	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKCAJAIO_00357	2.68e-49	-	3.2.2.10	-	L	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKCAJAIO_00358	5.54e-273	femA	2.3.2.17	-	V	ko:K11694	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
HKCAJAIO_00359	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKCAJAIO_00360	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKCAJAIO_00361	7.42e-114	pacL	-	-	P	-	-	-	cation transport ATPase
HKCAJAIO_00362	1.76e-258	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKCAJAIO_00363	5.65e-286	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKCAJAIO_00365	5.84e-13	sacB	2.4.1.10, 2.4.1.9	GH68	G	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyl hydrolase 68 family
HKCAJAIO_00366	1.06e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKCAJAIO_00367	2.64e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKCAJAIO_00368	1.36e-96	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HKCAJAIO_00369	4.33e-62	ylbG	-	-	S	-	-	-	UPF0298 protein
HKCAJAIO_00370	2.77e-271	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HKCAJAIO_00371	8.19e-190	livH	-	-	E	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKCAJAIO_00372	7.76e-183	livM	-	-	E	ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKCAJAIO_00373	3.96e-177	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HKCAJAIO_00374	6.53e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HKCAJAIO_00375	9.82e-92	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
HKCAJAIO_00376	1.52e-57	acuB	-	-	S	ko:K04767	-	ko00000	IMP dehydrogenase activity
HKCAJAIO_00377	6e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKCAJAIO_00378	1.91e-143	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKCAJAIO_00379	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKCAJAIO_00380	1.91e-158	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKCAJAIO_00381	1.18e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKCAJAIO_00389	9.95e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKCAJAIO_00390	9.03e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF1803)
HKCAJAIO_00391	4.01e-132	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HKCAJAIO_00392	3.96e-179	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKCAJAIO_00393	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKCAJAIO_00394	9.23e-246	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HKCAJAIO_00395	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKCAJAIO_00396	1.77e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKCAJAIO_00397	4.99e-180	phaB	5.3.3.14, 5.3.3.18	-	I	ko:K15866,ko:K18474	ko00061,ko00360,ko01120,map00061,map00360,map01120	ko00000,ko00001,ko01000,ko01004	Belongs to the enoyl-CoA hydratase isomerase family
HKCAJAIO_00398	2.67e-96	XK27_02735	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKCAJAIO_00399	1.88e-224	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKCAJAIO_00400	2.12e-40	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKCAJAIO_00401	1.31e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	2-Nitropropane dioxygenase
HKCAJAIO_00402	3.32e-211	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HKCAJAIO_00403	8.26e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKCAJAIO_00404	2.6e-297	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKCAJAIO_00405	6.1e-88	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKCAJAIO_00406	1.19e-93	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKCAJAIO_00407	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKCAJAIO_00408	2.95e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKCAJAIO_00409	9.33e-177	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HKCAJAIO_00410	6.58e-116	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKCAJAIO_00411	9.38e-84	-	-	-	L	ko:K07498	-	ko00000	Transposase
HKCAJAIO_00412	7.33e-310	rny	-	-	D	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKCAJAIO_00413	8.72e-111	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00414	1.37e-165	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	transcriptional
HKCAJAIO_00415	4.36e-210	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKCAJAIO_00416	4.7e-70	-	2.7.1.202	-	GT	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKCAJAIO_00417	3.01e-64	-	2.7.1.202	-	GT	ko:K02768,ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKCAJAIO_00418	4.81e-168	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKCAJAIO_00419	9.18e-47	fruA	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKCAJAIO_00420	0.0	gor	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKCAJAIO_00421	1.32e-310	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKCAJAIO_00423	1.8e-271	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HKCAJAIO_00424	1.48e-290	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKCAJAIO_00425	0.0	gtf1	-	-	M	-	-	-	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HKCAJAIO_00426	0.0	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HKCAJAIO_00427	1.13e-37	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
HKCAJAIO_00428	1.99e-64	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKCAJAIO_00429	1.55e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKCAJAIO_00430	2.07e-172	ydaF_2	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKCAJAIO_00431	3.89e-84	WQ51_03320	-	-	S	-	-	-	cog cog4835
HKCAJAIO_00432	2.26e-117	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKCAJAIO_00433	4.46e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKCAJAIO_00434	6.49e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKCAJAIO_00435	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00436	1.12e-27	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKCAJAIO_00437	9.06e-181	-	-	-	F	-	-	-	AdP-ribose pyrophosphatase
HKCAJAIO_00438	7.62e-271	nadR	-	-	H	-	-	-	adenylyltransferase
HKCAJAIO_00439	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKCAJAIO_00440	3.88e-92	def_1	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKCAJAIO_00441	4.4e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKCAJAIO_00442	0.0	lmrA1	-	-	V	ko:K02021,ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00443	0.0	lmrA2	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00444	2.1e-24	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKCAJAIO_00445	1.53e-100	sptS	-	-	T	-	-	-	Histidine kinase
HKCAJAIO_00446	1.38e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKCAJAIO_00447	3.91e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKCAJAIO_00448	1.37e-205	yitL	-	-	S	ko:K00243	-	ko00000	Protein conserved in bacteria
HKCAJAIO_00449	1.35e-46	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKCAJAIO_00450	7.35e-190	usp	3.5.1.104, 3.5.1.28	CBM50	S	ko:K15125,ko:K17733,ko:K21449,ko:K21471,ko:K22278,ko:K22409	ko05133,map05133	ko00000,ko00001,ko00536,ko01000,ko01002,ko01011,ko02000	pathogenesis
HKCAJAIO_00451	3.19e-90	sip	-	-	M	-	-	-	LysM domain protein
HKCAJAIO_00452	4.56e-244	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKCAJAIO_00456	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKCAJAIO_00457	2.54e-211	-	-	-	K	-	-	-	transcriptional regulator (lysR family)
HKCAJAIO_00458	6.15e-234	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKCAJAIO_00459	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKCAJAIO_00460	1.38e-163	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-Methyltransferase
HKCAJAIO_00461	4.05e-224	prsA	3.1.3.16, 5.2.1.8	-	O	ko:K01802,ko:K03769,ko:K07533,ko:K20074	-	ko00000,ko01000,ko01009,ko03110	peptidyl-prolyl cis-trans isomerase activity
HKCAJAIO_00462	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKCAJAIO_00463	1.67e-29	-	-	-	M	-	-	-	GBS Bsp-like repeat
HKCAJAIO_00464	1.85e-241	-	-	-	M	-	-	-	GBS Bsp-like repeat
HKCAJAIO_00465	9.52e-45	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
HKCAJAIO_00466	5.09e-126	-	3.4.17.14, 3.5.1.28	-	NU	ko:K01448,ko:K02395,ko:K07260	ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036	amidase activity
HKCAJAIO_00467	4.68e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKCAJAIO_00468	1.73e-291	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	mutations do not affect methionine salvage in vivo however
HKCAJAIO_00469	5.78e-245	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKCAJAIO_00470	4.21e-285	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKCAJAIO_00471	2.67e-166	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HKCAJAIO_00472	3.91e-268	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HKCAJAIO_00473	2.44e-191	icaB	-	-	G	-	-	-	deacetylase
HKCAJAIO_00474	2.09e-303	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKCAJAIO_00475	1.5e-197	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKCAJAIO_00476	1.32e-195	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	Transporter
HKCAJAIO_00478	3.61e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKCAJAIO_00479	1.88e-139	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKCAJAIO_00480	7.34e-63	-	2.3.1.128, 5.2.1.8	-	J	ko:K03768,ko:K03790	-	ko00000,ko01000,ko03009,ko03110	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKCAJAIO_00481	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKCAJAIO_00482	5.88e-23	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKCAJAIO_00483	4.44e-160	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKCAJAIO_00484	1.78e-102	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase F(0) sector subunit b
HKCAJAIO_00485	3.66e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKCAJAIO_00486	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKCAJAIO_00487	9.48e-204	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKCAJAIO_00488	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKCAJAIO_00489	6.23e-97	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKCAJAIO_00490	3.51e-293	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKCAJAIO_00491	7.86e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKCAJAIO_00492	6.58e-175	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKCAJAIO_00493	5.91e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKCAJAIO_00494	5.52e-207	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	dna polymerase iii
HKCAJAIO_00495	8.56e-179	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HKCAJAIO_00496	2.84e-73	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKCAJAIO_00497	1.46e-205	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKCAJAIO_00498	1.39e-297	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter
HKCAJAIO_00499	3.22e-71	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HKCAJAIO_00500	7.94e-141	mur1	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	mannosyl-glycoprotein
HKCAJAIO_00501	3.41e-192	XK27_04800	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKCAJAIO_00502	4.96e-116	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HKCAJAIO_00503	1.98e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKCAJAIO_00504	1.99e-69	-	-	-	-	-	-	-	-
HKCAJAIO_00505	1.94e-34	-	-	-	-	-	-	-	-
HKCAJAIO_00506	1.54e-80	-	-	-	-	-	-	-	-
HKCAJAIO_00507	2.41e-79	-	-	-	S	-	-	-	membrane
HKCAJAIO_00508	2.48e-226	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKCAJAIO_00509	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKCAJAIO_00510	1.42e-52	ynzC	-	-	S	-	-	-	UPF0291 protein
HKCAJAIO_00511	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	permease
HKCAJAIO_00513	6.07e-33	-	2.7.1.208, 2.7.1.211	-	G	ko:K02755,ko:K02756,ko:K02757,ko:K02777,ko:K02808,ko:K02809,ko:K02810,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKCAJAIO_00514	6.05e-93	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HKCAJAIO_00515	1.02e-177	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HKCAJAIO_00516	1.5e-180	ppiA	5.2.1.8	-	O	ko:K01802,ko:K03767,ko:K03768	ko01503,ko04217,map01503,map04217	ko00000,ko00001,ko01000,ko03110,ko04147	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKCAJAIO_00517	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
HKCAJAIO_00518	4.58e-156	-	-	-	L	-	-	-	Transposase
HKCAJAIO_00523	1.21e-215	lysR	-	-	K	-	-	-	transcriptional regulator (lysR family)
HKCAJAIO_00524	6.92e-101	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKCAJAIO_00525	1.71e-208	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKCAJAIO_00526	6.68e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKCAJAIO_00527	2.02e-288	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	uracil Permease
HKCAJAIO_00528	8.28e-222	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKCAJAIO_00529	9.61e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase glutamine chain
HKCAJAIO_00530	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	carbamoyl-phosphate synthetase ammonia chain
HKCAJAIO_00531	1.8e-308	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00532	2.11e-171	-	-	-	S	-	-	-	Putative SAM-dependent methyltransferase
HKCAJAIO_00533	2.61e-34	yknX	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKCAJAIO_00534	2.69e-49	yknX	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKCAJAIO_00535	2.28e-23	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	permease protein
HKCAJAIO_00536	2.27e-46	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	efflux transmembrane transporter activity
HKCAJAIO_00537	4.71e-37	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	efflux transmembrane transporter activity
HKCAJAIO_00538	3.14e-101	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKCAJAIO_00539	2.46e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKCAJAIO_00540	8.12e-243	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00541	1.25e-23	-	-	-	L	-	-	-	Integrase core domain
HKCAJAIO_00542	1.62e-152	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_00543	5.19e-61	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_00544	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
HKCAJAIO_00545	4.58e-156	-	-	-	L	-	-	-	Transposase
HKCAJAIO_00546	5.72e-149	hrtB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKCAJAIO_00549	2.72e-126	-	-	-	S	-	-	-	MucBP domain
HKCAJAIO_00550	3.02e-59	-	-	-	M	-	-	-	YSIRK type signal peptide
HKCAJAIO_00551	0.0	-	-	-	M	-	-	-	the current gene model (or a revised gene model) may contain a
HKCAJAIO_00553	0.0	msbA_1	-	-	V	ko:K18887	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_00554	0.0	lmrA	-	-	V	ko:K06147,ko:K18888	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_00555	4.12e-253	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKCAJAIO_00556	7.37e-158	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKCAJAIO_00557	8.65e-293	hk02	-	-	T	-	-	-	signal transduction protein with a C-terminal ATPase domain
HKCAJAIO_00558	4.15e-170	rr02	-	-	KT	-	-	-	response regulator
HKCAJAIO_00559	2.67e-278	thiF	2.7.7.73	-	H	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKCAJAIO_00560	8.21e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKCAJAIO_00561	1.79e-157	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKCAJAIO_00562	6.51e-249	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HKCAJAIO_00563	5.22e-37	XK27_00085	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
HKCAJAIO_00565	4.31e-182	-	-	-	F	-	-	-	Phosphorylase superfamily
HKCAJAIO_00566	8.88e-147	-	-	-	S	-	-	-	VIT family
HKCAJAIO_00567	3.68e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKCAJAIO_00568	1.5e-279	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HKCAJAIO_00569	1.29e-24	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	alanine dehydrogenase activity
HKCAJAIO_00570	2.16e-57	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HKCAJAIO_00571	9.49e-317	merA	-	-	C	-	-	-	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKCAJAIO_00572	3.96e-137	-	-	-	J	ko:K09962	-	ko00000	protein conserved in bacteria
HKCAJAIO_00573	6.57e-195	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HKCAJAIO_00574	2.38e-224	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKCAJAIO_00575	1.5e-231	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HKCAJAIO_00576	9.21e-244	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKCAJAIO_00577	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKCAJAIO_00578	8.64e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	AdP-ribose pyrophosphatase
HKCAJAIO_00579	1.47e-41	-	-	-	-	-	-	-	-
HKCAJAIO_00580	2.99e-151	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKCAJAIO_00582	9.15e-10	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
HKCAJAIO_00583	3e-59	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
HKCAJAIO_00584	1.95e-14	-	-	-	M	ko:K02460	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	domain protein
HKCAJAIO_00585	2.09e-244	dgs	2.4.1.208	GT4	M	ko:K13677	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKCAJAIO_00586	0.0	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKCAJAIO_00587	5.47e-29	-	-	-	-	-	-	-	-
HKCAJAIO_00588	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKCAJAIO_00589	1.12e-217	-	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKCAJAIO_00590	6.47e-209	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HKCAJAIO_00591	9.03e-29	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HKCAJAIO_00592	1.01e-151	hly-III	-	-	K	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HKCAJAIO_00593	3.81e-35	-	-	-	K	-	-	-	hmm pf08876
HKCAJAIO_00594	1.76e-297	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HKCAJAIO_00595	3.13e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	synthase
HKCAJAIO_00596	5.15e-214	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKCAJAIO_00597	7.02e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKCAJAIO_00598	2.97e-30	-	-	-	-	-	-	-	-
HKCAJAIO_00599	5.14e-287	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKCAJAIO_00600	1.93e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKCAJAIO_00601	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKCAJAIO_00602	8.67e-228	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	Homocysteine
HKCAJAIO_00603	5.22e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF1912)
HKCAJAIO_00604	1.1e-20	-	-	-	L	-	-	-	Helix-hairpin-helix DNA-binding motif class 1
HKCAJAIO_00605	1.49e-138	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKCAJAIO_00606	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKCAJAIO_00607	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKCAJAIO_00608	4.29e-256	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKCAJAIO_00609	3.44e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKCAJAIO_00612	1.44e-268	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein S1
HKCAJAIO_00615	2.58e-131	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3862)
HKCAJAIO_00616	2.5e-90	-	-	-	M	-	-	-	Pfam SNARE associated Golgi protein
HKCAJAIO_00617	3.82e-295	murN	-	-	V	ko:K12554	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	FemAB family
HKCAJAIO_00618	1.83e-74	-	-	-	S	-	-	-	oxidoreductase
HKCAJAIO_00619	2.73e-84	-	-	-	S	-	-	-	oxidoreductase
HKCAJAIO_00620	1.29e-64	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HKCAJAIO_00621	7.82e-111	XK27_09440	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HKCAJAIO_00622	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKCAJAIO_00623	3.17e-231	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKCAJAIO_00624	1.15e-47	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HKCAJAIO_00625	3.24e-151	-	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKCAJAIO_00626	7.69e-170	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00627	1.23e-101	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain protein
HKCAJAIO_00628	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKCAJAIO_00629	9.87e-12	-	-	-	-	-	-	-	-
HKCAJAIO_00630	1.27e-135	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKCAJAIO_00631	7.29e-61	-	-	-	K	ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HKCAJAIO_00632	2.87e-47	yugF	-	-	I	-	-	-	carboxylic ester hydrolase activity
HKCAJAIO_00633	5.04e-29	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKCAJAIO_00634	9.86e-202	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKCAJAIO_00635	5.03e-192	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKCAJAIO_00636	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
HKCAJAIO_00637	7.55e-136	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKCAJAIO_00638	5.77e-81	licT	-	-	K	ko:K02538,ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HKCAJAIO_00639	1.21e-69	licT	-	-	K	ko:K02538,ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HKCAJAIO_00640	2.18e-112	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKCAJAIO_00641	9.96e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HKCAJAIO_00642	1.16e-212	era	-	-	M	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKCAJAIO_00643	1.16e-199	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKCAJAIO_00644	2.68e-137	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKCAJAIO_00645	1.63e-168	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
HKCAJAIO_00646	5.15e-93	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	Major Facilitator
HKCAJAIO_00647	1.5e-44	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HKCAJAIO_00648	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKCAJAIO_00649	5.69e-105	smpB	-	-	O	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKCAJAIO_00650	0.0	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKCAJAIO_00651	1.08e-84	yugI	-	-	J	ko:K07570	-	ko00000	RNA binding protein, contains ribosomal protein S1 domain
HKCAJAIO_00652	7e-268	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
HKCAJAIO_00653	1.34e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	Catabolite control protein A
HKCAJAIO_00654	2.03e-35	XK27_07735	-	-	S	-	-	-	YjbR
HKCAJAIO_00655	6.38e-130	yyaQ	-	-	V	-	-	-	Protein conserved in bacteria
HKCAJAIO_00656	1.03e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKCAJAIO_00657	1.03e-101	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKCAJAIO_00658	1.75e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKCAJAIO_00659	2.22e-34	WQ51_00785	-	-	-	-	-	-	-
HKCAJAIO_00660	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HKCAJAIO_00661	1.45e-280	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HKCAJAIO_00662	8.04e-158	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKCAJAIO_00663	4.21e-208	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKCAJAIO_00664	1.24e-258	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKCAJAIO_00665	1.29e-279	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKCAJAIO_00666	1.92e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HKCAJAIO_00667	1.48e-71	XK26_04240	-	-	S	-	-	-	Belongs to the UPF0342 family
HKCAJAIO_00668	6.06e-223	hicD2	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKCAJAIO_00669	6.18e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKCAJAIO_00670	2.28e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKCAJAIO_00671	3.43e-197	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HKCAJAIO_00672	0.0	msrR	-	-	K	-	-	-	Transcriptional regulator
HKCAJAIO_00673	4.07e-199	ydiA	-	-	P	ko:K03304,ko:K11041	ko05150,map05150	ko00000,ko00001,ko02000,ko02042	C4-dicarboxylate transporter malic acid transport protein
HKCAJAIO_00674	1.56e-256	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
HKCAJAIO_00675	5.21e-126	mip	-	-	S	-	-	-	hydroperoxide reductase activity
HKCAJAIO_00676	0.0	rumA	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKCAJAIO_00677	7.72e-66	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKCAJAIO_00678	5.56e-124	-	-	-	-	-	-	-	-
HKCAJAIO_00679	7.77e-250	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_00680	3.81e-37	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_00681	3.6e-51	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_00682	1.24e-85	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
HKCAJAIO_00683	3.82e-95	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
HKCAJAIO_00685	3.12e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HKCAJAIO_00686	4.98e-85	yqeB	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HKCAJAIO_00688	2.15e-45	-	-	-	-	-	-	-	-
HKCAJAIO_00689	7.8e-35	-	-	-	S	-	-	-	CAAX protease self-immunity
HKCAJAIO_00690	1.61e-54	-	-	-	S	-	-	-	CAAX protease self-immunity
HKCAJAIO_00691	2.23e-35	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKCAJAIO_00692	3.1e-124	-	-	-	-	-	-	-	-
HKCAJAIO_00693	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKCAJAIO_00694	1.61e-221	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKCAJAIO_00695	8.44e-71	-	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKCAJAIO_00696	6.13e-236	-	-	-	S	-	-	-	CRISPR-associated protein Csn2 subfamily St
HKCAJAIO_00697	4.65e-189	XK27_03010	-	-	S	ko:K08986	-	ko00000	TIGR03943 family
HKCAJAIO_00698	4.63e-199	XK27_03015	-	-	S	ko:K07089	-	ko00000	permease
HKCAJAIO_00700	0.0	tex	-	-	K	ko:K06959	-	ko00000	Transcriptional accessory protein
HKCAJAIO_00701	1.45e-55	WQ51_05770	-	-	KT	-	-	-	PspC domain
HKCAJAIO_00702	3.49e-219	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKCAJAIO_00703	1.51e-190	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKCAJAIO_00704	1.14e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKCAJAIO_00705	1.66e-91	ytxH	-	-	S	-	-	-	General stress protein
HKCAJAIO_00707	1.23e-228	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HKCAJAIO_00708	0.0	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HKCAJAIO_00709	3.62e-60	-	-	-	S	-	-	-	CHY zinc finger
HKCAJAIO_00710	1.8e-308	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00711	1.09e-112	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	biotin synthase
HKCAJAIO_00713	2.97e-45	XK27_12190	-	-	S	-	-	-	protein conserved in bacteria
HKCAJAIO_00714	0.0	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00715	6.38e-297	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKCAJAIO_00717	1.83e-86	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HKCAJAIO_00718	0.0	-	-	-	L	-	-	-	helicase
HKCAJAIO_00719	7.54e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_00720	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKCAJAIO_00721	4.3e-216	-	-	-	M	-	-	-	LysM domain
HKCAJAIO_00722	2.16e-29	-	-	-	-	-	-	-	-
HKCAJAIO_00723	3.13e-222	-	-	-	S	ko:K07025	-	ko00000	hydrolase
HKCAJAIO_00724	1.02e-149	pgm	-	-	G	-	-	-	Phosphoglycerate mutase
HKCAJAIO_00725	2.49e-105	-	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKCAJAIO_00726	2.83e-196	-	3.5.1.28	-	M	ko:K01447,ko:K07273	-	ko00000,ko01000	Glycosyl hydrolase, family 25
HKCAJAIO_00727	1.14e-35	-	-	-	P	-	-	-	Hemerythrin HHE cation binding domain protein
HKCAJAIO_00728	6.94e-146	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKCAJAIO_00729	4.51e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HKCAJAIO_00730	1.03e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HKCAJAIO_00731	4.34e-07	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKCAJAIO_00732	1.45e-131	sdh	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKCAJAIO_00733	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKCAJAIO_00734	4.75e-82	-	-	-	-	-	-	-	-
HKCAJAIO_00737	4.17e-163	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKCAJAIO_00738	0.0	-	-	-	S	-	-	-	KAP family P-loop domain
HKCAJAIO_00739	1.73e-169	-	-	-	S	-	-	-	Protein conserved in bacteria
HKCAJAIO_00740	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKCAJAIO_00741	2.66e-77	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKCAJAIO_00742	1.85e-128	spd	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKCAJAIO_00743	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKCAJAIO_00744	5.7e-188	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKCAJAIO_00745	4.09e-95	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HKCAJAIO_00746	2.18e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HKCAJAIO_00747	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HKCAJAIO_00748	2.71e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKCAJAIO_00749	6.73e-145	sodA	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HKCAJAIO_00750	1.71e-288	-	-	-	V	-	-	-	D-alanyl-D-alanine carboxypeptidase
HKCAJAIO_00751	4.5e-150	pppA	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HKCAJAIO_00752	3.18e-118	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKCAJAIO_00753	5.82e-105	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HKCAJAIO_00754	7.8e-38	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
HKCAJAIO_00755	1.76e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HKCAJAIO_00756	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKCAJAIO_00757	2.68e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3165)
HKCAJAIO_00758	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKCAJAIO_00759	1.9e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKCAJAIO_00760	1.01e-237	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKCAJAIO_00761	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKCAJAIO_00762	2.64e-303	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKCAJAIO_00763	1.14e-158	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKCAJAIO_00764	1.04e-124	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	cell septum assembly
HKCAJAIO_00765	2.56e-46	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
HKCAJAIO_00766	2.05e-185	ylmH	-	-	T	ko:K02487,ko:K06596	ko02020,ko02025,map02020,map02025	ko00000,ko00001,ko00002,ko01001,ko02022,ko02035	S4 RNA-binding domain
HKCAJAIO_00767	2.95e-186	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division protein DivIVA
HKCAJAIO_00768	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKCAJAIO_00769	5.37e-41	-	-	-	-	-	-	-	-
HKCAJAIO_00770	1.93e-12	-	-	-	-	-	-	-	-
HKCAJAIO_00771	7.72e-295	mntH_2	-	-	P	-	-	-	Mn2 and Fe2 transporters of the NRAMP family
HKCAJAIO_00772	1.39e-61	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L31
HKCAJAIO_00773	6.83e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKCAJAIO_00774	1.77e-236	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	domain protein
HKCAJAIO_00775	1.92e-197	gst	-	-	O	ko:K11209	-	ko00000,ko01000	Glutathione S-transferase
HKCAJAIO_00776	4.54e-240	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKCAJAIO_00777	2.65e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKCAJAIO_00778	5.57e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKCAJAIO_00779	3.18e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKCAJAIO_00780	1.2e-140	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKCAJAIO_00781	1.24e-298	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKCAJAIO_00782	4.29e-228	-	-	-	S	-	-	-	37-kD nucleoid-associated bacterial protein
HKCAJAIO_00783	2.1e-135	pvaA	-	-	M	ko:K02395	-	ko00000,ko02035	lytic transglycosylase activity
HKCAJAIO_00784	0.0	yfiB1	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00785	0.0	XK27_10035	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00786	3.08e-14	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKCAJAIO_00787	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKCAJAIO_00788	2.07e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Membrane protein involved in D-alanine export
HKCAJAIO_00789	4.98e-48	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKCAJAIO_00790	1.09e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKCAJAIO_00791	4.1e-111	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_00792	9.69e-72	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_00793	7.94e-26	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_00794	0.0	-	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537	ko00190,map00190	ko00000,ko00001,ko01000	cation transport ATPase
HKCAJAIO_00795	0.0	pabB	2.6.1.85, 4.1.3.38	-	EH	ko:K01665,ko:K03342,ko:K13950	ko00790,map00790	ko00000,ko00001,ko01000,ko01007	component I
HKCAJAIO_00799	0.0	-	-	-	S	ko:K06919	-	ko00000	DNA primase
HKCAJAIO_00800	1.88e-191	-	-	-	KL	ko:K06919	-	ko00000	Phage plasmid primase P4 family
HKCAJAIO_00801	1.9e-30	-	-	-	-	-	-	-	-
HKCAJAIO_00805	2.15e-27	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HKCAJAIO_00806	5.02e-37	-	-	-	K	-	-	-	transcriptional
HKCAJAIO_00807	9.47e-282	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKCAJAIO_00809	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKCAJAIO_00810	2.2e-212	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	reductase
HKCAJAIO_00811	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HKCAJAIO_00812	1.52e-122	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKCAJAIO_00813	5.7e-124	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKCAJAIO_00814	6.6e-158	coaB	6.3.2.5	-	H	ko:K21977	ko00770,map00770	ko00000,ko00001,ko00002,ko01000	Phosphopantothenate-cysteine ligase
HKCAJAIO_00815	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKCAJAIO_00816	4.04e-86	ciaR	-	-	T	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKCAJAIO_00817	1.19e-49	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKCAJAIO_00818	2.38e-53	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKCAJAIO_00819	1.11e-114	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKCAJAIO_00820	4.58e-156	-	-	-	L	-	-	-	Transposase
HKCAJAIO_00821	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
HKCAJAIO_00822	2.67e-281	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00823	1.92e-36	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKCAJAIO_00824	2.52e-263	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
HKCAJAIO_00825	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
HKCAJAIO_00826	0.0	vpr	3.4.21.96	-	O	ko:K01361,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HKCAJAIO_00827	1.5e-28	-	-	-	L	-	-	-	Helix-turn-helix domain
HKCAJAIO_00828	1.68e-106	-	-	-	L	-	-	-	Helix-turn-helix domain
HKCAJAIO_00829	9.94e-209	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_00830	0.0	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00831	1.98e-40	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	rRNA binding
HKCAJAIO_00832	2.47e-222	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKCAJAIO_00833	5.78e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase small domain protein
HKCAJAIO_00834	1.27e-71	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HKCAJAIO_00835	3e-121	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HKCAJAIO_00836	2.52e-30	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKCAJAIO_00837	4.43e-82	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKCAJAIO_00838	6.79e-91	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKCAJAIO_00839	6.01e-246	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HKCAJAIO_00840	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKCAJAIO_00841	9.61e-247	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKCAJAIO_00842	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKCAJAIO_00843	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HKCAJAIO_00844	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKCAJAIO_00845	1.32e-106	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HKCAJAIO_00846	3.85e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKCAJAIO_00847	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HKCAJAIO_00849	8.38e-42	-	-	-	-	-	-	-	-
HKCAJAIO_00850	1.82e-17	-	-	-	-	-	-	-	-
HKCAJAIO_00851	1.84e-83	aldR	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HKCAJAIO_00852	3.72e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKCAJAIO_00853	1.17e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HKCAJAIO_00854	7.17e-172	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKCAJAIO_00855	2.72e-122	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HKCAJAIO_00856	2.81e-22	-	-	-	D	-	-	-	nuclear chromosome segregation
HKCAJAIO_00857	1.88e-176	yejC	-	-	S	-	-	-	cyclic nucleotide-binding protein
HKCAJAIO_00858	2.08e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKCAJAIO_00859	3.04e-232	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKCAJAIO_00860	1.2e-207	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKCAJAIO_00861	2.45e-211	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKCAJAIO_00862	2.63e-44	-	-	-	K	-	-	-	Cold shock protein domain
HKCAJAIO_00863	8.77e-56	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-Shock Protein
HKCAJAIO_00864	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
HKCAJAIO_00865	4.58e-156	-	-	-	L	-	-	-	Transposase
HKCAJAIO_00866	8.04e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_00867	0.0	copB	3.6.3.4	-	P	ko:K01533	-	ko00000,ko01000	P-type ATPase
HKCAJAIO_00868	8.04e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_00869	2.63e-243	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKCAJAIO_00870	1.8e-218	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKCAJAIO_00871	8.39e-279	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKCAJAIO_00872	6.38e-77	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
HKCAJAIO_00873	8.04e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_00874	3.85e-72	hsdS	2.1.1.72, 3.1.21.3	-	V	ko:K01154,ko:K07317	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HKCAJAIO_00875	1.1e-143	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HKCAJAIO_00876	9.82e-203	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HKCAJAIO_00877	1.33e-07	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
HKCAJAIO_00878	8.54e-98	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
HKCAJAIO_00879	1.69e-128	XK27_10720	-	-	D	-	-	-	peptidase activity
HKCAJAIO_00880	0.0	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKCAJAIO_00883	4.73e-221	yeiH	-	-	S	-	-	-	Membrane
HKCAJAIO_00884	1.86e-153	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	muramidase
HKCAJAIO_00885	9.47e-107	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_00886	8.86e-214	cpsY	-	-	K	-	-	-	Transcriptional regulator
HKCAJAIO_00887	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKCAJAIO_00888	7.71e-77	phnA	-	-	P	ko:K06193	ko01120,map01120	ko00000	Alkylphosphonate utilization operon protein PhnA
HKCAJAIO_00889	3.92e-134	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_00890	5.28e-146	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_00891	5.5e-203	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKCAJAIO_00892	4.5e-177	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKCAJAIO_00893	2.18e-10	-	-	-	-	-	-	-	-
HKCAJAIO_00894	2.8e-36	-	-	-	-	-	-	-	-
HKCAJAIO_00895	3.67e-78	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKCAJAIO_00896	1.65e-22	adhP	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKCAJAIO_00897	7.7e-39	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKCAJAIO_00898	4.62e-94	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
HKCAJAIO_00899	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKCAJAIO_00900	1.82e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HKCAJAIO_00901	9e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKCAJAIO_00902	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKCAJAIO_00903	8e-113	niaX	-	-	-	ko:K16788	-	ko00000,ko02000	-
HKCAJAIO_00904	1.3e-116	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HKCAJAIO_00905	5.25e-165	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HKCAJAIO_00906	1.46e-203	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKCAJAIO_00907	2.89e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKCAJAIO_00908	4.4e-216	-	-	-	GK	-	-	-	ROK family
HKCAJAIO_00909	9.91e-204	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKCAJAIO_00910	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKCAJAIO_00911	2.32e-195	-	-	-	S	-	-	-	TraX protein
HKCAJAIO_00912	2.93e-157	spaR	-	-	KT	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKCAJAIO_00913	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HKCAJAIO_00914	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKCAJAIO_00915	1.4e-195	XK27_05470	-	-	E	-	-	-	Methionine synthase
HKCAJAIO_00916	1.01e-99	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HKCAJAIO_00917	6.02e-64	pspE	-	-	P	ko:K03972	-	ko00000	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKCAJAIO_00918	2.52e-50	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
HKCAJAIO_00919	1.66e-57	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	Acetoin reductase
HKCAJAIO_00921	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKCAJAIO_00922	1.77e-200	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HKCAJAIO_00924	7.54e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_00926	3.68e-271	nirJ	-	-	C	ko:K06139,ko:K22227	-	ko00000	radical SAM domain protein
HKCAJAIO_00927	3.67e-174	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HKCAJAIO_00928	9.01e-75	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKCAJAIO_00929	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKCAJAIO_00930	5.45e-172	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HKCAJAIO_00932	2e-207	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_00933	1.52e-125	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_00934	3.51e-146	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKCAJAIO_00935	9.28e-15	-	-	-	-	-	-	-	-
HKCAJAIO_00936	1.89e-127	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HKCAJAIO_00937	3.17e-205	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKCAJAIO_00938	8.27e-269	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKCAJAIO_00939	2.78e-250	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
HKCAJAIO_00940	2.92e-11	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HKCAJAIO_00941	3.95e-24	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKCAJAIO_00942	2.43e-103	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKCAJAIO_00945	9.83e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
HKCAJAIO_00946	6.95e-152	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
HKCAJAIO_00947	3.18e-31	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
HKCAJAIO_00948	1.89e-23	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
HKCAJAIO_00949	1.84e-15	dinF	-	-	V	-	-	-	Mate efflux family protein
HKCAJAIO_00951	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HKCAJAIO_00952	3.54e-114	-	-	-	S	-	-	-	TraX protein
HKCAJAIO_00953	1.23e-124	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HKCAJAIO_00954	8.38e-190	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKCAJAIO_00955	7.37e-224	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKCAJAIO_00956	5.07e-236	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKCAJAIO_00957	7.15e-73	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKCAJAIO_00958	7.74e-174	cas6	-	-	S	ko:K19091	-	ko00000,ko01000,ko02048	CRISPR-associated endoribonuclease Cas6
HKCAJAIO_00959	0.0	csm1	-	-	S	ko:K07016	-	ko00000,ko02048	CRISPR-associated protein Csm1 family
HKCAJAIO_00960	1.29e-83	csm2	-	-	L	ko:K19138	-	ko00000,ko02048	Csm2 Type III-A
HKCAJAIO_00961	9.77e-152	csm3	-	-	L	ko:K09002	-	ko00000,ko02048	RAMP superfamily
HKCAJAIO_00962	1.04e-215	csm4	-	-	L	ko:K19139	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm4 family
HKCAJAIO_00963	2.24e-262	csm5	-	-	L	ko:K19140	-	ko00000,ko02048	CRISPR-associated RAMP protein, Csm5 family
HKCAJAIO_00964	5.24e-10	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKCAJAIO_00965	1.46e-30	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKCAJAIO_00966	2.2e-158	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKCAJAIO_00967	4.34e-145	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKCAJAIO_00968	6.37e-09	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	amidase activity
HKCAJAIO_00969	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	transporter
HKCAJAIO_00970	8.93e-82	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_00971	1.02e-28	yecS	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	amino acid transport
HKCAJAIO_00972	1.17e-05	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKCAJAIO_00973	0.0	sasH	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKCAJAIO_00974	1.56e-45	-	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	nucleotide catabolic process
HKCAJAIO_00975	4.64e-135	yfiF3	-	-	K	-	-	-	sequence-specific DNA binding
HKCAJAIO_00976	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKCAJAIO_00977	7.07e-307	agcS	-	-	E	ko:K03310	-	ko00000	(Alanine) symporter
HKCAJAIO_00978	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKCAJAIO_00979	2.95e-307	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	o-acetylhomoserine
HKCAJAIO_00980	6.24e-78	-	-	-	Q	-	-	-	phosphatase activity
HKCAJAIO_00981	5.48e-79	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKCAJAIO_00982	1.48e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKCAJAIO_00983	3.31e-143	hsdS2	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
HKCAJAIO_00984	1.02e-124	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
HKCAJAIO_00985	5.47e-61	XK27_04775	-	-	S	ko:K09155	-	ko00000	hemerythrin HHE cation binding domain
HKCAJAIO_00986	5.24e-195	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKCAJAIO_00987	1.28e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKCAJAIO_00988	7.52e-95	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKCAJAIO_00989	1.99e-58	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HKCAJAIO_00990	8.38e-184	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HKCAJAIO_00991	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKCAJAIO_00992	2.07e-202	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	phosphate
HKCAJAIO_00993	4.63e-201	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKCAJAIO_00994	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	phosphate transport system permease
HKCAJAIO_00995	5.27e-193	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKCAJAIO_00996	1.75e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKCAJAIO_00997	7.71e-148	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKCAJAIO_00998	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKCAJAIO_00999	1.88e-249	xerS	-	-	D	ko:K04763	-	ko00000,ko03036	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HKCAJAIO_01000	7.23e-238	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HKCAJAIO_01003	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKCAJAIO_01004	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	4-alpha-glucanotransferase
HKCAJAIO_01006	4.79e-34	tatA	-	-	U	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	protein secretion
HKCAJAIO_01007	1.83e-156	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKCAJAIO_01008	0.0	ywbL	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HKCAJAIO_01009	7.41e-297	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	peroxidase
HKCAJAIO_01010	3.04e-200	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HKCAJAIO_01011	6.83e-232	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type enterochelin transport system, periplasmic component
HKCAJAIO_01012	1.75e-174	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01013	1.02e-213	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKCAJAIO_01014	1.91e-211	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKCAJAIO_01015	2.83e-41	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01016	4.24e-111	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01017	5.89e-70	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01018	1.89e-83	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01019	2.03e-158	pulA2	3.2.1.1, 3.2.1.41	CBM48,GH13	G	ko:K01176,ko:K01200	ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01020	1.84e-143	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
HKCAJAIO_01021	3.83e-79	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	GBS Bsp-like repeat
HKCAJAIO_01022	3.13e-14	-	3.5.1.28	-	S	ko:K01448,ko:K02395,ko:K21471	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036	dextransucrase activity
HKCAJAIO_01023	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HKCAJAIO_01024	1.05e-275	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKCAJAIO_01025	3.38e-232	acoB	1.2.4.1	-	C	ko:K00162,ko:K21417	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKCAJAIO_01026	1.07e-236	acoA	1.2.4.1	-	C	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKCAJAIO_01027	2.53e-55	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HKCAJAIO_01028	8.81e-105	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HKCAJAIO_01029	5.9e-46	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HKCAJAIO_01030	1.19e-65	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HKCAJAIO_01031	1.7e-206	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated endoribonuclease Cas2
HKCAJAIO_01032	2.64e-216	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKCAJAIO_01033	6.11e-142	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasE
HKCAJAIO_01034	2.03e-171	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasD
HKCAJAIO_01035	2.89e-232	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
HKCAJAIO_01036	1.65e-134	casB	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR system CASCADE complex protein CasB
HKCAJAIO_01037	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
HKCAJAIO_01038	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
HKCAJAIO_01039	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HKCAJAIO_01040	3.43e-299	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKCAJAIO_01041	6.69e-162	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKCAJAIO_01042	5.21e-275	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKCAJAIO_01043	5.27e-32	dacA1	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKCAJAIO_01044	1.12e-31	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
HKCAJAIO_01045	4.7e-33	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
HKCAJAIO_01046	7.17e-106	dacA1	3.4.16.4	-	M	ko:K01286	-	ko00000,ko01000	Belongs to the peptidase S11 family
HKCAJAIO_01047	4.34e-200	-	-	-	S	-	-	-	Phospholipase, patatin family
HKCAJAIO_01048	3.75e-90	-	-	-	E	-	-	-	GDSL-like protein
HKCAJAIO_01049	3.14e-38	-	-	-	E	-	-	-	Lysophospholipase L1 and related esterases
HKCAJAIO_01050	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	unusual protein kinase
HKCAJAIO_01051	3.34e-52	-	-	-	S	-	-	-	granule-associated protein
HKCAJAIO_01052	1.96e-172	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKCAJAIO_01053	1.74e-22	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKCAJAIO_01054	1.68e-254	XK27_12525	-	-	S	-	-	-	hmm pf01594
HKCAJAIO_01055	2.23e-115	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HKCAJAIO_01056	8.95e-91	supH	3.1.3.102, 3.1.3.104	-	Q	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	phosphatase activity
HKCAJAIO_01057	6.28e-19	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKCAJAIO_01058	6.98e-124	-	-	-	V	-	-	-	VanZ like family
HKCAJAIO_01059	1.46e-260	-	-	-	L	-	-	-	Transposase
HKCAJAIO_01060	9.66e-275	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKCAJAIO_01061	2.63e-25	wzx	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKCAJAIO_01062	7.87e-216	wzx	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKCAJAIO_01063	7.24e-303	cps1C	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKCAJAIO_01064	3.29e-110	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HKCAJAIO_01065	3.62e-42	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKCAJAIO_01066	1.98e-127	-	-	-	M	-	-	-	group 2 family protein
HKCAJAIO_01067	1.04e-126	-	-	-	-	-	-	-	-
HKCAJAIO_01068	9e-90	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKCAJAIO_01069	4.35e-78	-	-	-	L	-	-	-	Transposase DDE domain
HKCAJAIO_01070	7.14e-93	-	-	-	L	-	-	-	Transposase DDE domain
HKCAJAIO_01071	6.38e-29	rgpAc	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	group 1 family protein
HKCAJAIO_01072	0.0	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKCAJAIO_01073	2.55e-07	cpsE	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKCAJAIO_01074	3.4e-143	cpsD	-	-	D	-	-	-	COG0489 ATPases involved in chromosome partitioning
HKCAJAIO_01075	4.17e-142	capA	-	-	M	-	-	-	biosynthesis protein
HKCAJAIO_01076	3.83e-174	cpsB	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
HKCAJAIO_01077	0.0	cps4A	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKCAJAIO_01078	7.54e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_01079	9.39e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	purine nucleoside phosphorylase
HKCAJAIO_01080	2.67e-48	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
HKCAJAIO_01081	1.12e-86	gat	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine amidotransferase
HKCAJAIO_01082	3.11e-80	clcA2	-	-	P	-	-	-	chloride
HKCAJAIO_01083	3.56e-192	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKCAJAIO_01084	5.38e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF1697)
HKCAJAIO_01085	3.95e-293	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKCAJAIO_01086	7.14e-157	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKCAJAIO_01089	1.95e-145	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HKCAJAIO_01090	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Dipeptidase
HKCAJAIO_01091	2.78e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKCAJAIO_01092	1.39e-111	XK27_03610	-	-	K	-	-	-	Gnat family
HKCAJAIO_01093	6.53e-44	-	-	-	L	ko:K07491	-	ko00000	Transposase
HKCAJAIO_01094	1.82e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKCAJAIO_01095	5.79e-39	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKCAJAIO_01096	3.15e-115	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKCAJAIO_01097	1.44e-156	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKCAJAIO_01098	3.03e-105	XK27_09115	-	-	M	-	-	-	LysM domain
HKCAJAIO_01099	1.12e-119	ebsA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HKCAJAIO_01100	4.32e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKCAJAIO_01101	1.95e-127	sipC	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKCAJAIO_01102	1.1e-284	XK27_05225	-	-	G	-	-	-	COG0457 FOG TPR repeat
HKCAJAIO_01103	1.22e-231	XK27_05220	-	-	S	-	-	-	permease
HKCAJAIO_01104	2.48e-120	mutX	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKCAJAIO_01105	1.99e-209	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKCAJAIO_01106	7.31e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HKCAJAIO_01107	5.35e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKCAJAIO_01108	1.52e-263	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKCAJAIO_01109	2.9e-229	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKCAJAIO_01110	1.38e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKCAJAIO_01111	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	cation transport ATPase
HKCAJAIO_01112	1.19e-89	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKCAJAIO_01113	1.69e-60	XK27_00115	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
HKCAJAIO_01114	5.66e-189	XK27_00835	-	-	S	-	-	-	hydrolases of the HAD superfamily
HKCAJAIO_01115	2.58e-294	femX	2.3.2.10, 2.3.2.16	-	V	ko:K05363,ko:K11693	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01011	protein involved in methicillin resistance
HKCAJAIO_01116	2.51e-47	-	-	-	F	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HKCAJAIO_01117	1.46e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Metal-dependent hydrolases of the beta-lactamase superfamily I
HKCAJAIO_01118	9.32e-316	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKCAJAIO_01119	2.49e-166	yycF	-	-	KT	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKCAJAIO_01120	5.43e-180	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01121	9.79e-194	peb1A	-	-	ET	ko:K02030,ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
HKCAJAIO_01122	8.31e-159	XK27_07620	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_01123	3.52e-143	-	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HKCAJAIO_01124	6.78e-177	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKCAJAIO_01125	4.09e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
HKCAJAIO_01126	1.45e-296	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKCAJAIO_01128	5.18e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKCAJAIO_01129	1.92e-19	-	-	-	G	-	-	-	Domain of unknown function (DUF4832)
HKCAJAIO_01130	5.75e-267	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKCAJAIO_01131	2.38e-223	birA	6.3.4.15	-	HK	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKCAJAIO_01132	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKCAJAIO_01133	1.12e-116	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKCAJAIO_01134	1.05e-209	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKCAJAIO_01135	2.71e-27	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HKCAJAIO_01138	5.73e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKCAJAIO_01139	4.32e-279	-	-	-	P	-	-	-	chloride
HKCAJAIO_01140	1.27e-55	pheA	1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5	-	E	ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
HKCAJAIO_01141	0.0	eriC	-	-	P	ko:K03281	-	ko00000	Chloride transporter, ClC family
HKCAJAIO_01142	1.42e-97	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKCAJAIO_01144	3.12e-162	XK27_08875	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKCAJAIO_01145	7.51e-194	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
HKCAJAIO_01146	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKCAJAIO_01147	2.68e-174	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01148	6.79e-191	XK27_08840	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKCAJAIO_01149	2.91e-230	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
HKCAJAIO_01152	9.67e-49	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HKCAJAIO_01153	1.68e-31	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HKCAJAIO_01154	6.86e-11	crpB	-	-	Q	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HKCAJAIO_01156	0.0	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_01157	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKCAJAIO_01158	1.04e-239	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKCAJAIO_01159	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKCAJAIO_01160	8.12e-194	XK27_00020	-	-	J	-	-	-	Belongs to the SUA5 family
HKCAJAIO_01161	2.76e-146	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKCAJAIO_01162	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKCAJAIO_01163	1.64e-57	ysdA	-	-	L	-	-	-	Membrane
HKCAJAIO_01164	7.51e-242	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKCAJAIO_01165	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKCAJAIO_01166	3.05e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKCAJAIO_01167	2.31e-230	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HKCAJAIO_01169	1.54e-52	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKCAJAIO_01170	2.09e-124	ypmS	-	-	S	-	-	-	Protein conserved in bacteria
HKCAJAIO_01171	4.24e-185	ypmR	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKCAJAIO_01172	1.18e-190	WQ51_01275	-	-	S	-	-	-	DegV family
HKCAJAIO_01173	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKCAJAIO_01174	1.72e-94	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKCAJAIO_01175	2.83e-203	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKCAJAIO_01176	1.35e-202	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKCAJAIO_01177	1.72e-40	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease VII activity
HKCAJAIO_01178	9.08e-314	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKCAJAIO_01180	3.81e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKCAJAIO_01181	9.02e-163	dnaD	-	-	-	ko:K02086	-	ko00000	-
HKCAJAIO_01182	5.91e-234	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKCAJAIO_01183	6.44e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKCAJAIO_01184	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease recj
HKCAJAIO_01185	4.46e-179	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKCAJAIO_01186	4.43e-222	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKCAJAIO_01187	1.15e-152	XK27_05445	-	-	G	-	-	-	UDPglucose--hexose-1-phosphate uridylyltransferase
HKCAJAIO_01188	1.42e-286	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKCAJAIO_01189	1.01e-251	-	-	-	L	ko:K07481	-	ko00000	transposase, IS4 family
HKCAJAIO_01190	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKCAJAIO_01191	7.62e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoribosyl-ATP
HKCAJAIO_01192	7.31e-81	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKCAJAIO_01193	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKCAJAIO_01194	1.75e-168	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKCAJAIO_01195	2.08e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKCAJAIO_01196	4.07e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HKCAJAIO_01197	2.16e-300	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKCAJAIO_01198	8.39e-151	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKCAJAIO_01199	9.09e-235	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKCAJAIO_01200	3.66e-253	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKCAJAIO_01202	1.74e-42	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_01203	2.66e-74	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_01204	6.11e-31	-	-	-	L	-	-	-	Transposase
HKCAJAIO_01205	8.74e-49	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_01206	1.5e-30	XK27_08085	-	-	-	-	-	-	-
HKCAJAIO_01207	1.5e-119	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
HKCAJAIO_01208	2.04e-17	XK27_08080	-	-	G	-	-	-	Exopolysaccharide biosynthesis protein
HKCAJAIO_01209	2.41e-181	hisJ	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
HKCAJAIO_01210	1.2e-158	-	-	-	S	-	-	-	tigr01906
HKCAJAIO_01211	6.89e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKCAJAIO_01212	7.79e-185	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKCAJAIO_01213	3.27e-277	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HKCAJAIO_01216	1.47e-307	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_01217	3.31e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKCAJAIO_01218	4.07e-144	rmlC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKCAJAIO_01219	7.83e-206	rfbA	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKCAJAIO_01220	6.9e-261	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	oxidoreductase
HKCAJAIO_01221	3.79e-39	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	transporter
HKCAJAIO_01222	4.63e-18	zupT	-	-	P	ko:K07238	-	ko00000,ko02000	Mediates zinc uptake. May also transport other divalent cations
HKCAJAIO_01223	1.15e-189	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKCAJAIO_01224	9.04e-161	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKCAJAIO_01225	2.86e-92	mesH	-	-	S	-	-	-	GtrA-like protein
HKCAJAIO_01226	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKCAJAIO_01227	1.47e-217	ybbR	-	-	S	-	-	-	Protein conserved in bacteria
HKCAJAIO_01228	1.15e-160	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKCAJAIO_01229	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain protein
HKCAJAIO_01230	1.02e-192	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HKCAJAIO_01231	0.0	mprF	2.3.2.3	-	J	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKCAJAIO_01232	4.3e-169	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha beta hydrolase
HKCAJAIO_01233	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	abc transporter atp-binding protein
HKCAJAIO_01234	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKCAJAIO_01235	9.56e-245	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKCAJAIO_01236	5.79e-39	-	6.3.2.2, 6.3.2.4	-	F	ko:K01919,ko:K01921	ko00270,ko00473,ko00480,ko00550,ko01100,ko01502,map00270,map00473,map00480,map00550,map01100,map01502	ko00000,ko00001,ko00002,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKCAJAIO_01237	0.0	gapN	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKCAJAIO_01238	0.0	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_01239	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKCAJAIO_01240	3.31e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein Hpr
HKCAJAIO_01241	8.43e-282	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate dehydrogenase
HKCAJAIO_01242	8.58e-271	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HKCAJAIO_01243	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKCAJAIO_01244	3.36e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKCAJAIO_01245	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKCAJAIO_01246	8.44e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKCAJAIO_01248	3.37e-92	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
HKCAJAIO_01249	1.28e-35	-	-	-	L	-	-	-	Transposase (IS116 IS110 IS902 family)
HKCAJAIO_01250	3.42e-212	ypuA	-	-	S	-	-	-	secreted protein
HKCAJAIO_01251	1.88e-67	ywkD	-	-	E	ko:K08234	-	ko00000	COG0346 LactoylglutaTHIone lyase and related lyases
HKCAJAIO_01252	6e-167	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase (surface protein transpeptidase)
HKCAJAIO_01253	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKCAJAIO_01254	2.06e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKCAJAIO_01255	0.0	noxE	-	-	P	-	-	-	NADH oxidase
HKCAJAIO_01256	0.0	yheS_1	-	-	S	-	-	-	abc transporter atp-binding protein
HKCAJAIO_01257	3.43e-107	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKCAJAIO_01258	4.44e-108	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
HKCAJAIO_01259	4.85e-56	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Belongs to the pyridoxine kinase family
HKCAJAIO_01260	1.46e-112	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKCAJAIO_01262	1.03e-304	ycxD	-	-	K	-	-	-	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKCAJAIO_01263	2.66e-74	nrdD_1	1.1.98.6, 1.17.4.1	-	F	ko:K00525,ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleoside-triphosphate reductase
HKCAJAIO_01266	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKCAJAIO_01267	1.07e-120	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKCAJAIO_01268	1.96e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKCAJAIO_01269	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKCAJAIO_01270	1.69e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKCAJAIO_01271	6.31e-223	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKCAJAIO_01272	2.9e-254	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKCAJAIO_01273	5.31e-120	pat	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	acetyltransferase
HKCAJAIO_01274	1.82e-17	-	-	-	-	-	-	-	-
HKCAJAIO_01275	8.38e-42	-	-	-	-	-	-	-	-
HKCAJAIO_01276	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKCAJAIO_01277	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKCAJAIO_01278	7.76e-168	yfnB	3.8.1.2	-	E	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	hydrolase
HKCAJAIO_01279	4.85e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HKCAJAIO_01280	1.88e-39	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HKCAJAIO_01281	2.3e-130	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HKCAJAIO_01283	3.56e-189	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKCAJAIO_01284	2.45e-128	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	transport system, permease component
HKCAJAIO_01285	4.01e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKCAJAIO_01286	5.97e-246	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKCAJAIO_01287	2.48e-171	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKCAJAIO_01288	2.94e-203	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01292	3.36e-272	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKCAJAIO_01293	0.0	-	2.7.7.73, 2.7.7.80	-	E	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	metalloendopeptidase activity
HKCAJAIO_01294	1.05e-195	mutR	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HKCAJAIO_01295	3.53e-54	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKCAJAIO_01297	1.77e-158	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
HKCAJAIO_01298	7.76e-33	XK27_09825	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	'abc transporter, ATP-binding protein
HKCAJAIO_01301	1.61e-120	-	-	-	S	ko:K06940	-	ko00000	Fe-S-cluster oxidoreductase
HKCAJAIO_01302	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HKCAJAIO_01303	8.96e-173	yxdL	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKCAJAIO_01304	9.46e-213	-	-	-	T	-	-	-	Histidine kinase
HKCAJAIO_01305	2.13e-158	graR	-	-	KT	ko:K19082	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKCAJAIO_01306	1e-99	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKCAJAIO_01307	4.96e-86	pbuX	-	-	F	ko:K16169	-	ko00000,ko02000	xanthine permease
HKCAJAIO_01308	1.48e-153	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKCAJAIO_01309	2.78e-316	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HKCAJAIO_01310	8.17e-241	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKCAJAIO_01311	4.2e-301	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKCAJAIO_01312	2.22e-85	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKCAJAIO_01313	3.23e-75	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKCAJAIO_01314	5.5e-34	csbD	-	-	K	-	-	-	CsbD-like
HKCAJAIO_01315	4.6e-294	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HKCAJAIO_01316	3.47e-142	XK27_02070	-	-	S	ko:K07078	-	ko00000	nitroreductase
HKCAJAIO_01317	1.37e-192	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HKCAJAIO_01318	2.96e-100	ywnA_2	-	-	K	-	-	-	Transcriptional regulator
HKCAJAIO_01319	1.07e-202	-	-	-	E	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKCAJAIO_01320	1.19e-294	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKCAJAIO_01321	2.35e-142	ydgI	-	-	C	-	-	-	Nitroreductase
HKCAJAIO_01322	1.33e-136	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKCAJAIO_01323	2.63e-204	yvgN	-	-	C	-	-	-	reductase
HKCAJAIO_01324	2.74e-231	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKCAJAIO_01325	0.0	XK27_07020	-	-	S	-	-	-	Belongs to the UPF0371 family
HKCAJAIO_01327	4.43e-71	saeR	-	-	K	ko:K10682	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKCAJAIO_01328	1.07e-86	-	-	-	S	-	-	-	Signal peptide protein, YSIRK family
HKCAJAIO_01329	1.49e-81	-	-	-	-	-	-	-	-
HKCAJAIO_01330	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKCAJAIO_01331	5.47e-44	-	-	-	-	-	-	-	-
HKCAJAIO_01332	1.08e-14	-	-	-	IQ	-	-	-	PFAM AMP-dependent synthetase and ligase
HKCAJAIO_01334	4.88e-140	-	-	-	E	-	-	-	LysE type translocator
HKCAJAIO_01335	6.23e-11	-	-	-	-	-	-	-	-
HKCAJAIO_01336	1.96e-12	-	-	-	-	-	-	-	-
HKCAJAIO_01337	0.0	-	-	-	M	-	-	-	family 8
HKCAJAIO_01339	1.21e-225	hrtB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKCAJAIO_01340	1.62e-152	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01341	1.31e-195	-	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MatE
HKCAJAIO_01342	2.93e-10	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HKCAJAIO_01343	5.73e-137	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
HKCAJAIO_01344	6.25e-227	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKCAJAIO_01345	3.19e-290	-	-	-	I	-	-	-	radical SAM domain protein
HKCAJAIO_01346	3.57e-24	-	-	-	I	-	-	-	radical SAM domain protein
HKCAJAIO_01348	7.24e-205	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HKCAJAIO_01349	6.28e-193	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_01350	2.1e-24	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_01351	7.51e-71	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_01353	1.48e-119	-	-	-	-	-	-	-	-
HKCAJAIO_01354	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	ATPase involved in DNA repair
HKCAJAIO_01355	2.27e-293	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKCAJAIO_01356	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	-beta-galactosidase
HKCAJAIO_01357	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	transporter
HKCAJAIO_01358	1.19e-257	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKCAJAIO_01359	6.03e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKCAJAIO_01360	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDPglucose--hexose-1-phosphate uridylyltransferase
HKCAJAIO_01361	1.57e-280	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKCAJAIO_01362	1.4e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKCAJAIO_01363	6.92e-13	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_01364	1.18e-34	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_01365	1.38e-276	zmpB	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	M26 IgA1-specific Metallo-endopeptidase C-terminal region
HKCAJAIO_01366	8.99e-24	zmpB	-	-	M	ko:K08643	-	ko00000,ko01000,ko01002	M26 IgA1-specific Metallo-endopeptidase C-terminal region
HKCAJAIO_01367	4.19e-124	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01368	1.91e-47	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01369	0.0	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HKCAJAIO_01370	1.03e-80	-	-	-	L	-	-	-	Transposase
HKCAJAIO_01371	2.67e-186	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01372	1.58e-39	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01373	1.17e-147	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01374	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKCAJAIO_01375	8.16e-241	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKCAJAIO_01376	1.15e-173	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKCAJAIO_01377	6.44e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKCAJAIO_01380	8.07e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKCAJAIO_01381	1.12e-224	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKCAJAIO_01382	4.61e-156	yvqF	-	-	KT	ko:K11622	ko02020,map02020	ko00000,ko00001	membrane
HKCAJAIO_01383	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKCAJAIO_01384	7.75e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKCAJAIO_01385	1.1e-314	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKCAJAIO_01386	4.26e-221	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKCAJAIO_01387	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKCAJAIO_01388	6.79e-62	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-directed 5'-3' RNA polymerase activity
HKCAJAIO_01389	3.57e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKCAJAIO_01390	8.97e-309	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKCAJAIO_01391	7.18e-193	XK27_02985	-	-	S	-	-	-	overlaps another CDS with the same product name
HKCAJAIO_01392	1.63e-190	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HKCAJAIO_01393	2.43e-83	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional
HKCAJAIO_01394	2.9e-159	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01395	2.73e-172	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
HKCAJAIO_01396	3.46e-218	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_01397	8.41e-260	amiE	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_01398	2.01e-213	amiD	-	-	P	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_01399	0.0	amiC	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_01400	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKCAJAIO_01401	3.05e-182	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_01402	0.0	amiA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, family 5
HKCAJAIO_01403	7.37e-60	-	-	-	L	ko:K07483	-	ko00000	Transposase
HKCAJAIO_01404	2.84e-203	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
HKCAJAIO_01405	3.33e-106	amiF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKCAJAIO_01406	2.09e-51	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
HKCAJAIO_01407	1.24e-279	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HKCAJAIO_01408	4.08e-123	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_01409	4.61e-101	-	-	-	L	-	-	-	Transposase
HKCAJAIO_01410	1.15e-233	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKCAJAIO_01411	1.81e-220	yjbO	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKCAJAIO_01412	1.56e-193	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKCAJAIO_01413	1.24e-156	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	Gtp pyrophosphokinase
HKCAJAIO_01414	5.5e-134	yjbK	-	-	S	-	-	-	Adenylate cyclase
HKCAJAIO_01415	2.07e-226	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKCAJAIO_01416	4.54e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HKCAJAIO_01417	1.46e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKCAJAIO_01418	2.81e-151	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKCAJAIO_01419	4.49e-167	-	-	-	T	ko:K07010	-	ko00000,ko01002	peptidase C26
HKCAJAIO_01420	1.61e-154	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HKCAJAIO_01421	0.0	rgpF	-	-	M	ko:K07272	-	ko00000,ko01000,ko01003,ko01005	Rhamnan synthesis protein F
HKCAJAIO_01422	1.35e-236	rgpE	-	GT2	M	ko:K12998	-	ko00000,ko01000,ko01003,ko01005	COG0463 Glycosyltransferases involved in cell wall biogenesis
HKCAJAIO_01423	2.09e-287	rgpD	3.6.3.40	-	P	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKCAJAIO_01424	4.54e-183	rgpC	-	-	GM	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HKCAJAIO_01425	5.23e-230	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HKCAJAIO_01426	3.29e-285	rgpA	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
HKCAJAIO_01427	1.31e-170	-	-	-	S	-	-	-	Predicted membrane protein (DUF2142)
HKCAJAIO_01428	1.33e-160	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	transferase activity, transferring glycosyl groups
HKCAJAIO_01429	5.33e-272	rgpX3	-	-	S	-	-	-	polysaccharide biosynthetic process
HKCAJAIO_01430	3.81e-64	-	-	-	S	ko:K09153	-	ko00000	Uncharacterized conserved protein (DUF2304)
HKCAJAIO_01431	1.97e-160	-	-	-	S	-	-	-	Glycosyl transferase family 2
HKCAJAIO_01432	1.9e-207	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKCAJAIO_01433	3.02e-312	-	-	-	-	-	-	-	-
HKCAJAIO_01434	7.3e-216	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	COG0463, glycosyltransferases involved in cell wall biogenesis
HKCAJAIO_01435	1.98e-73	yitW	-	-	K	-	-	-	metal-sulfur cluster biosynthetic enzyme
HKCAJAIO_01436	3.03e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKCAJAIO_01437	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKCAJAIO_01438	1.9e-27	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKCAJAIO_01439	4.07e-175	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HKCAJAIO_01440	9.57e-268	arcT	-	-	E	-	-	-	Aminotransferase
HKCAJAIO_01441	7.6e-176	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter
HKCAJAIO_01442	6.76e-185	XK27_04395	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HKCAJAIO_01443	2.15e-109	XK27_04400	3.6.1.55	-	F	ko:K03574,ko:K12944	-	ko00000,ko01000,ko03400	Nudix family
HKCAJAIO_01444	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKCAJAIO_01446	3.3e-72	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKCAJAIO_01447	6.37e-40	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HKCAJAIO_01448	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKCAJAIO_01449	8.35e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01450	1.84e-24	XK27_00735	-	-	-	-	-	-	-
HKCAJAIO_01451	1.9e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKCAJAIO_01452	8.41e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HKCAJAIO_01453	2.22e-173	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKCAJAIO_01456	1.25e-85	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein possibly involved in aromatic compounds catabolism
HKCAJAIO_01457	1.17e-40	ycaO	-	-	O	ko:K06889,ko:K07397,ko:K09136	-	ko00000,ko03009	OsmC-like protein
HKCAJAIO_01459	1.61e-197	-	-	-	EG	-	-	-	Permeases of the drug metabolite transporter (DMT) superfamily
HKCAJAIO_01461	1.22e-140	csn2	-	-	S	ko:K19137	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csn2)
HKCAJAIO_01462	7.78e-69	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKCAJAIO_01463	2.97e-210	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKCAJAIO_01464	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKCAJAIO_01465	7.46e-149	serB	3.1.3.3	-	E	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	phosphoserine phosphatase
HKCAJAIO_01466	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKCAJAIO_01467	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKCAJAIO_01468	1.07e-141	-	-	-	S	-	-	-	IA, variant 1
HKCAJAIO_01469	3.76e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	effector of murein hydrolase
HKCAJAIO_01470	4.04e-77	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Effector of murein hydrolase LrgA
HKCAJAIO_01472	3.55e-79	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HKCAJAIO_01473	3.47e-72	ogt	2.1.1.63, 3.2.2.20	-	L	ko:K00567,ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	methylated-DNA-[protein]-cysteine S-methyltransferase activity
HKCAJAIO_01474	2.15e-280	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKCAJAIO_01475	3.26e-135	-	-	-	M	-	-	-	Acetyltransferase GNAT family
HKCAJAIO_01476	3.61e-267	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKCAJAIO_01477	5.76e-124	-	-	-	GK	-	-	-	ROK family
HKCAJAIO_01478	1.61e-93	gloA	4.4.1.5	-	E	ko:K01759,ko:K15772	ko00620,ko02010,map00620,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Lactoylglutathione lyase
HKCAJAIO_01479	6.33e-71	XK27_08050	-	-	O	-	-	-	stress-induced mitochondrial fusion
HKCAJAIO_01480	4.81e-25	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	HflC and HflK could regulate a protease
HKCAJAIO_01481	3.44e-263	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	spermidine putrescine ABC transporter
HKCAJAIO_01482	1.79e-171	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component II
HKCAJAIO_01483	2e-179	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type spermidine putrescine transport system, permease component I
HKCAJAIO_01484	5.6e-272	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKCAJAIO_01485	4.06e-219	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HKCAJAIO_01486	7.94e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKCAJAIO_01487	1.49e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKCAJAIO_01488	0.0	amy	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKCAJAIO_01489	1.29e-188	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKCAJAIO_01490	1.17e-129	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	gtp cyclohydrolase
HKCAJAIO_01491	0.0	ydaO	-	-	E	-	-	-	amino acid
HKCAJAIO_01492	1.93e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKCAJAIO_01493	9.09e-50	ylqC	-	-	L	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKCAJAIO_01494	1.87e-57	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKCAJAIO_01495	2.67e-219	tehB	2.1.1.265	-	PQ	ko:K16868	-	ko00000,ko01000	tellurite resistance protein tehb
HKCAJAIO_01496	2.43e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKCAJAIO_01497	1.22e-97	-	-	-	S	-	-	-	QueT transporter
HKCAJAIO_01498	4.27e-11	-	-	-	L	-	-	-	Transposase DDE domain
HKCAJAIO_01499	1.43e-115	-	-	-	L	-	-	-	Transposase DDE domain
HKCAJAIO_01500	7.79e-237	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKCAJAIO_01501	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKCAJAIO_01502	3.26e-110	ccl	-	-	S	-	-	-	cog cog4708
HKCAJAIO_01503	1.03e-205	rbn	-	-	E	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKCAJAIO_01504	4.94e-212	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HKCAJAIO_01505	1.06e-295	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HKCAJAIO_01506	2.39e-126	XK27_07830	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase GNAT Family
HKCAJAIO_01507	2.13e-295	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKCAJAIO_01508	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKCAJAIO_01509	2.9e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HKCAJAIO_01510	2.5e-183	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKCAJAIO_01511	8.44e-186	nodB3	-	-	G	-	-	-	deacetylase
HKCAJAIO_01512	1.5e-181	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase
HKCAJAIO_01513	4.12e-56	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HKCAJAIO_01514	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKCAJAIO_01515	8.36e-203	corA	-	-	P	-	-	-	CorA-like protein
HKCAJAIO_01516	7.5e-83	yjqA	-	-	S	-	-	-	Bacterial PH domain
HKCAJAIO_01517	4.57e-129	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter
HKCAJAIO_01518	5.28e-203	rgg	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HKCAJAIO_01519	1.09e-257	yjbB	-	-	G	-	-	-	Permeases of the major facilitator superfamily
HKCAJAIO_01520	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKCAJAIO_01521	1.63e-155	ywaF	-	-	S	-	-	-	Integral membrane protein (intg_mem_TP0381)
HKCAJAIO_01522	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKCAJAIO_01526	9.46e-200	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKCAJAIO_01527	2.01e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01528	1.32e-147	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_01529	1.22e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_01530	9.64e-248	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKCAJAIO_01531	9.48e-43	copZ	-	-	P	-	-	-	Heavy metal-associated domain protein
HKCAJAIO_01532	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKCAJAIO_01533	4.28e-97	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor, CopY TcrY family
HKCAJAIO_01534	6.12e-184	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKCAJAIO_01535	1.37e-288	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKCAJAIO_01536	1.53e-128	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the TrpF family
HKCAJAIO_01537	2.28e-172	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HKCAJAIO_01538	2.69e-231	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKCAJAIO_01539	1.01e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	anthranilate
HKCAJAIO_01540	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKCAJAIO_01541	2.72e-56	MA20_20425	2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5	-	E	ko:K00800,ko:K03785,ko:K04092,ko:K04782	ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
HKCAJAIO_01542	1.7e-72	-	-	-	-	-	-	-	-
HKCAJAIO_01543	0.0	ctpE	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKCAJAIO_01545	5.31e-59	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKCAJAIO_01546	6.16e-38	-	-	-	L	-	-	-	transposase activity
HKCAJAIO_01547	6.01e-167	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HKCAJAIO_01548	2.17e-134	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKCAJAIO_01549	8.12e-80	WQ51_02910	-	-	S	-	-	-	Protein of unknown function, DUF536
HKCAJAIO_01550	1.23e-82	XK27_02560	-	-	S	-	-	-	cog cog2151
HKCAJAIO_01551	0.0	ilvD	4.2.1.9	-	E	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HKCAJAIO_01552	3.35e-289	ytfP	-	-	S	ko:K07007	-	ko00000	Flavoprotein
HKCAJAIO_01554	4.36e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKCAJAIO_01555	8.46e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
HKCAJAIO_01556	7.69e-232	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKCAJAIO_01557	1.5e-171	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01558	6.15e-95	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HKCAJAIO_01559	4.47e-13	-	-	-	-	-	-	-	-
HKCAJAIO_01560	1.93e-67	-	-	-	S	-	-	-	CD20-like family
HKCAJAIO_01561	3.82e-140	-	-	-	-	-	-	-	-
HKCAJAIO_01562	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	ATP-dependent Clp protease ATP-binding subunit
HKCAJAIO_01563	4.36e-263	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKCAJAIO_01564	2.78e-179	XK27_06665	-	-	Q	-	-	-	Methyltransferase domain protein
HKCAJAIO_01565	9.81e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKCAJAIO_01566	2.01e-139	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HKCAJAIO_01567	5.51e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKCAJAIO_01568	1.59e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HKCAJAIO_01569	2.78e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HKCAJAIO_01570	1.84e-127	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HKCAJAIO_01571	3.49e-196	-	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKCAJAIO_01572	9.12e-76	-	-	-	-	-	-	-	-
HKCAJAIO_01573	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKCAJAIO_01574	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKCAJAIO_01575	7.49e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKCAJAIO_01576	6.32e-42	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
HKCAJAIO_01577	0.0	ascB	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKCAJAIO_01578	1.96e-125	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKCAJAIO_01579	2.31e-197	metQ	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HKCAJAIO_01580	3.02e-130	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	isochorismatase
HKCAJAIO_01581	6.34e-182	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HKCAJAIO_01582	2.61e-303	aspC	2.6.1.2, 2.6.1.66	-	E	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKCAJAIO_01583	7.54e-99	XK27_03180	-	-	T	-	-	-	universal stress protein
HKCAJAIO_01586	6.98e-202	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKCAJAIO_01587	1.17e-303	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	COG1253 Hemolysins and related proteins containing CBS domains
HKCAJAIO_01588	1.06e-184	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01589	0.0	nhaP1	-	-	P	ko:K03316	-	ko00000	NhaP-type Na H and K H antiporters
HKCAJAIO_01591	9e-127	mraW1	-	-	J	-	-	-	(SAM)-dependent
HKCAJAIO_01592	1.51e-236	ytqA	-	-	S	ko:K07139	-	ko00000	radical SAM protein
HKCAJAIO_01593	7.98e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKCAJAIO_01594	7.91e-115	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKCAJAIO_01595	5.22e-120	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HKCAJAIO_01596	4.78e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKCAJAIO_01597	1.48e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF4059)
HKCAJAIO_01598	1.61e-168	tcyN	3.6.3.21	-	E	ko:K02028,ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
HKCAJAIO_01599	5.95e-210	yxeN	-	-	P	ko:K02029,ko:K16959,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (Permease
HKCAJAIO_01600	1.27e-195	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC-type amino acid transport signal transduction systems, periplasmic component domain
HKCAJAIO_01602	2.53e-264	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKCAJAIO_01603	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	formate acetyltransferase'
HKCAJAIO_01604	6.92e-190	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	carbonic anhydrase
HKCAJAIO_01605	9.32e-112	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKCAJAIO_01606	5.58e-60	hsdS_1	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HKCAJAIO_01607	1.96e-113	-	-	-	D	-	-	-	nuclear chromosome segregation
HKCAJAIO_01608	9.95e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HKCAJAIO_01609	1.02e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01610	1.97e-233	-	-	-	V	-	-	-	COG1680 Beta-lactamase class C and other penicillin binding proteins
HKCAJAIO_01611	6.61e-179	cppA	-	-	E	-	-	-	CppA N-terminal
HKCAJAIO_01612	2.69e-56	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKCAJAIO_01613	7.59e-212	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKCAJAIO_01614	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKCAJAIO_01617	1.31e-63	spiA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
HKCAJAIO_01618	9.35e-36	blpT	-	-	-	-	-	-	-
HKCAJAIO_01619	4.64e-159	blpT	-	-	-	-	-	-	-
HKCAJAIO_01620	4.58e-156	-	-	-	L	-	-	-	Transposase
HKCAJAIO_01621	1.53e-212	-	-	-	L	ko:K07497	-	ko00000	integrase core domain
HKCAJAIO_01625	0.000703	-	-	-	-	-	-	-	-
HKCAJAIO_01626	2.55e-33	-	-	-	S	-	-	-	Bacteriocin class II with double-glycine leader peptide
HKCAJAIO_01629	3.68e-172	agrA	-	-	KT	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	phosphorelay signal transduction system
HKCAJAIO_01630	9.46e-298	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	protein histidine kinase activity
HKCAJAIO_01632	5.03e-311	mesE	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HKCAJAIO_01633	0.0	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKCAJAIO_01634	4.89e-133	comA	-	-	V	ko:K06148,ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKCAJAIO_01635	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01636	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01638	2.82e-122	XK27_09885	-	-	V	-	-	-	Glycopeptide antibiotics resistance protein
HKCAJAIO_01639	9.55e-287	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKCAJAIO_01640	4.03e-138	yutD	-	-	J	-	-	-	protein conserved in bacteria
HKCAJAIO_01641	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKCAJAIO_01643	2.26e-303	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKCAJAIO_01644	8.08e-236	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKCAJAIO_01645	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
HKCAJAIO_01646	3.89e-62	ftsL	-	-	D	-	-	-	cell division protein FtsL
HKCAJAIO_01647	1.54e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKCAJAIO_01648	6.56e-84	-	-	-	-	-	-	-	-
HKCAJAIO_01649	2.52e-34	-	-	-	-	-	-	-	-
HKCAJAIO_01650	3.81e-55	-	-	-	-	-	-	-	-
HKCAJAIO_01652	1.58e-42	-	-	-	J	-	-	-	Protein of unknown function (DUF805)
HKCAJAIO_01653	2.06e-31	-	-	-	D	-	-	-	nuclear chromosome segregation
HKCAJAIO_01654	8.59e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKCAJAIO_01655	1.43e-181	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKCAJAIO_01656	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKCAJAIO_01657	2.59e-172	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	abc transporter atp-binding protein
HKCAJAIO_01658	1.22e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKCAJAIO_01659	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKCAJAIO_01660	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HKCAJAIO_01661	2.47e-155	-	-	-	S	-	-	-	membrane
HKCAJAIO_01662	1.31e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKCAJAIO_01663	9.03e-80	-	-	-	KT	-	-	-	response to antibiotic
HKCAJAIO_01664	2.99e-127	yebC	-	-	M	-	-	-	Membrane
HKCAJAIO_01665	1.77e-24	yebC	-	-	M	-	-	-	Membrane
HKCAJAIO_01666	0.0	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
HKCAJAIO_01667	3.09e-223	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HKCAJAIO_01669	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKCAJAIO_01670	1.16e-244	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKCAJAIO_01671	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKCAJAIO_01672	1.01e-251	aroG	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKCAJAIO_01673	2.03e-251	aroH	2.5.1.54	-	E	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	ko00000,ko00001,ko00002,ko01000	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HKCAJAIO_01674	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKCAJAIO_01676	6.2e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKCAJAIO_01677	1.37e-219	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	Fructokinase
HKCAJAIO_01678	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
HKCAJAIO_01679	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKCAJAIO_01680	7.4e-227	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional
HKCAJAIO_01681	2.67e-96	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKCAJAIO_01682	9.01e-81	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	protein conserved in bacteria
HKCAJAIO_01683	1.22e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKCAJAIO_01684	1.43e-109	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HKCAJAIO_01685	2.5e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Belongs to the peptidase M24B family
HKCAJAIO_01687	6.03e-55	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
HKCAJAIO_01688	1.13e-74	-	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	'abc transporter, ATP-binding protein
HKCAJAIO_01691	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HKCAJAIO_01692	6.01e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	COG0598 Mg2 and Co2 transporters
HKCAJAIO_01693	5.06e-160	-	-	-	S	-	-	-	Pfam PF06570
HKCAJAIO_01695	2.03e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKCAJAIO_01696	2.07e-118	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKCAJAIO_01697	1.88e-62	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKCAJAIO_01698	1.39e-50	XK27_05745	-	-	-	-	-	-	-
HKCAJAIO_01699	6.75e-293	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HKCAJAIO_01704	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKCAJAIO_01705	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKCAJAIO_01706	3.39e-121	cvpA	-	-	S	ko:K03558	-	ko00000	toxin biosynthetic process
HKCAJAIO_01707	5.78e-19	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKCAJAIO_01708	4.7e-206	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKCAJAIO_01709	3.19e-146	spi	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKCAJAIO_01710	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKCAJAIO_01711	3.85e-63	azlD	-	-	E	-	-	-	branched-chain amino acid
HKCAJAIO_01712	7.27e-148	XK27_12120	-	-	E	-	-	-	AzlC protein
HKCAJAIO_01713	1.64e-238	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKCAJAIO_01714	6.26e-96	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKCAJAIO_01715	2.39e-156	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214, inactive homolog of metal-dependent proteases
HKCAJAIO_01716	6.45e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKCAJAIO_01717	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKCAJAIO_01718	4.75e-53	sle1	3.5.1.28	CBM50	M	ko:K22409	-	ko00000,ko01000	CHAP domain protein
HKCAJAIO_01719	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKCAJAIO_01720	1.12e-83	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HKCAJAIO_01721	1.08e-113	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HKCAJAIO_01722	1.82e-17	-	-	-	-	-	-	-	-
HKCAJAIO_01723	8.38e-42	-	-	-	-	-	-	-	-
HKCAJAIO_01724	9.51e-283	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKCAJAIO_01725	4.29e-57	-	-	-	L	ko:K07491	-	ko00000	Transposase
HKCAJAIO_01726	6.62e-62	-	-	-	L	ko:K07483	-	ko00000	transposase activity
HKCAJAIO_01727	6.11e-31	-	-	-	L	-	-	-	Transposase
HKCAJAIO_01728	3.23e-75	-	-	-	L	ko:K07497	-	ko00000	transposition
HKCAJAIO_01729	4.35e-108	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain protein
HKCAJAIO_01730	4.37e-131	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_01731	5.06e-54	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_01732	3.33e-242	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKCAJAIO_01733	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKCAJAIO_01734	4.66e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKCAJAIO_01735	4.89e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKCAJAIO_01736	2.67e-185	purR	-	-	F	ko:K09685	-	ko00000,ko03000	operon repressor
HKCAJAIO_01737	4.81e-229	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
HKCAJAIO_01738	4.63e-236	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC domain protein
HKCAJAIO_01739	2.73e-153	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKCAJAIO_01740	2.76e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKCAJAIO_01741	5.32e-209	rsgA	3.1.3.100	-	G	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKCAJAIO_01743	1.06e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKCAJAIO_01744	1.05e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKCAJAIO_01745	2.6e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	Hydrolase, tatd
HKCAJAIO_01746	1.14e-98	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HKCAJAIO_01747	5.36e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKCAJAIO_01748	5.03e-183	-	-	-	S	-	-	-	Macro domain protein
HKCAJAIO_01749	2.59e-13	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	thioesterase
HKCAJAIO_01750	1.18e-72	bta	1.8.1.8	-	CO	ko:K03671,ko:K03672	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko01000,ko03110	cell redox homeostasis
HKCAJAIO_01753	1.16e-17	-	-	-	-	-	-	-	-
HKCAJAIO_01755	3.46e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKCAJAIO_01756	1.37e-45	-	-	-	L	ko:K07491	-	ko00000	Transposase
HKCAJAIO_01757	9.33e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L34
HKCAJAIO_01758	0.0	-	-	-	L	ko:K07485	-	ko00000	Transposase
HKCAJAIO_01759	7.21e-239	jag	-	-	S	ko:K06346	-	ko00000	RNA-binding protein
HKCAJAIO_01760	1.8e-180	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKCAJAIO_01761	8.28e-73	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKCAJAIO_01762	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Argininosuccinate lyase
HKCAJAIO_01763	3.19e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKCAJAIO_01764	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKCAJAIO_01765	1.01e-104	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKCAJAIO_01766	1.82e-97	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	transmembrane transport
HKCAJAIO_01767	1.94e-155	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKCAJAIO_01768	1.69e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKCAJAIO_01769	3.28e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HKCAJAIO_01770	1.31e-113	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HKCAJAIO_01771	2.42e-49	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HKCAJAIO_01772	1.25e-15	-	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
HKCAJAIO_01773	6.08e-280	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKCAJAIO_01774	7.02e-103	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HKCAJAIO_01775	3.06e-27	XK27_09620	-	-	S	-	-	-	FMN reductase (NADPH) activity
HKCAJAIO_01776	5.98e-100	-	-	-	S	-	-	-	reductase
HKCAJAIO_01777	4.64e-77	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
HKCAJAIO_01778	3.86e-182	XK27_09615	-	-	C	ko:K19784	-	ko00000	reductase
HKCAJAIO_01779	4.96e-82	nirC_1	-	-	P	-	-	-	Formate nitrite transporter
HKCAJAIO_01780	9.39e-83	XK27_08585	-	-	S	ko:K16926	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HKCAJAIO_01781	5.94e-238	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKCAJAIO_01782	7.92e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKCAJAIO_01783	2.39e-154	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HKCAJAIO_01784	2.82e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKCAJAIO_01785	1.63e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKCAJAIO_01786	6.92e-105	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKCAJAIO_01787	9.35e-64	-	-	-	S	ko:K07025	-	ko00000	glycolate biosynthetic process
HKCAJAIO_01788	8.85e-85	-	-	-	S	ko:K07025	-	ko00000	phosphatase activity
HKCAJAIO_01789	1.41e-202	rrmA	2.1.1.187	-	Q	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	methyltransferase
HKCAJAIO_01791	1.7e-117	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKCAJAIO_01792	3.13e-86	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKCAJAIO_01793	2.25e-49	yeeD	-	-	O	ko:K07112	-	ko00000	sulfur carrier activity
HKCAJAIO_01794	1.26e-245	yeeE	-	-	S	ko:K07112	-	ko00000	Sulphur transport
HKCAJAIO_01795	5.51e-147	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKCAJAIO_01796	3.48e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
HKCAJAIO_01798	6.4e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HKCAJAIO_01799	1.17e-170	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKCAJAIO_01800	1.17e-143	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family protein
HKCAJAIO_01802	7.87e-87	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKCAJAIO_01803	5.18e-44	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKCAJAIO_01804	5.36e-07	lanR	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HKCAJAIO_01805	8.04e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKCAJAIO_01806	5.86e-227	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HKCAJAIO_01807	7.17e-17	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HKCAJAIO_01808	7.93e-94	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Competence protein ComGF
HKCAJAIO_01809	9.03e-22	-	-	-	NU	-	-	-	Type II secretory pathway pseudopilin
HKCAJAIO_01810	1.03e-75	cglD	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	Competence protein
HKCAJAIO_01811	2.23e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HKCAJAIO_01812	1.22e-185	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKCAJAIO_01813	1.89e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKCAJAIO_01814	1.13e-90	-	-	-	S	-	-	-	cog cog4699
HKCAJAIO_01815	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKCAJAIO_01816	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKCAJAIO_01817	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKCAJAIO_01818	1.65e-304	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKCAJAIO_01819	2.67e-250	ilvC	1.1.1.86	-	H	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKCAJAIO_01820	2.89e-100	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HKCAJAIO_01821	0.0	ilvB	2.2.1.6	-	EH	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HKCAJAIO_01822	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HKCAJAIO_01823	1.57e-11	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HKCAJAIO_01824	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HKCAJAIO_01825	1.87e-76	asp	-	-	S	-	-	-	cog cog1302
HKCAJAIO_01826	1.12e-287	norN	-	-	V	-	-	-	Mate efflux family protein
HKCAJAIO_01827	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKCAJAIO_01828	3.43e-77	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKCAJAIO_01829	5.24e-49	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	hydroxyacid-oxoacid transhydrogenase activity
HKCAJAIO_01830	1.16e-100	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKCAJAIO_01831	1.15e-165	adh	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKCAJAIO_01832	9.31e-84	-	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Dehydrogenase
HKCAJAIO_01833	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKCAJAIO_01834	3.67e-49	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HKCAJAIO_01835	4.39e-90	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HKCAJAIO_01836	4.14e-87	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HKCAJAIO_01837	3.49e-72	treB	2.7.1.201	-	G	ko:K02817,ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS System
HKCAJAIO_01838	2.66e-29	treR	-	-	K	ko:K03486,ko:K03710	-	ko00000,ko03000	DNA-binding transcription factor activity
HKCAJAIO_01839	1.53e-112	treR	-	-	K	ko:K03486	-	ko00000,ko03000	trehalose operon
HKCAJAIO_01840	1.6e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HKCAJAIO_01842	5.1e-12	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKCAJAIO_01843	1.51e-94	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKCAJAIO_01844	7.64e-113	-	-	-	L	-	-	-	Phage integrase family
HKCAJAIO_01845	9.73e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4298)
HKCAJAIO_01846	1.75e-80	cadC	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKCAJAIO_01847	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HKCAJAIO_01848	1.8e-175	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HKCAJAIO_01849	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
HKCAJAIO_01850	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKCAJAIO_01851	9.41e-265	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKCAJAIO_01852	2.84e-46	-	-	-	-	-	-	-	-
HKCAJAIO_01853	3.73e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_01854	2.62e-179	-	-	-	L	-	-	-	DNA integration
HKCAJAIO_01855	2.34e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	aldolase
HKCAJAIO_01857	1.52e-141	-	6.3.2.2	-	H	ko:K01919,ko:K06048	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	ergothioneine biosynthetic process
HKCAJAIO_01858	1.16e-79	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
HKCAJAIO_01859	2.41e-15	-	-	-	H	-	-	-	gamma-glutamylcysteine synthetase
HKCAJAIO_01860	5.1e-12	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKCAJAIO_01861	1.51e-94	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKCAJAIO_01862	2.13e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l17
HKCAJAIO_01863	5.37e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKCAJAIO_01864	1.57e-80	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKCAJAIO_01865	4.42e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKCAJAIO_01866	3.26e-22	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HKCAJAIO_01867	6.91e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKCAJAIO_01868	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKCAJAIO_01869	2.12e-293	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKCAJAIO_01870	1.03e-85	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HKCAJAIO_01871	2e-32	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	ribosomal protein l30
HKCAJAIO_01872	9.94e-104	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKCAJAIO_01873	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKCAJAIO_01874	1.44e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKCAJAIO_01875	3.78e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKCAJAIO_01876	4.1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKCAJAIO_01877	5.86e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKCAJAIO_01878	5.67e-64	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKCAJAIO_01879	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKCAJAIO_01880	3.08e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKCAJAIO_01881	4.36e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKCAJAIO_01882	3.58e-93	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKCAJAIO_01883	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKCAJAIO_01884	1.21e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKCAJAIO_01885	1.99e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKCAJAIO_01886	7.19e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKCAJAIO_01887	6e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKCAJAIO_01888	2.13e-135	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKCAJAIO_01889	7.78e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKCAJAIO_01890	7.41e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKCAJAIO_01891	1.78e-240	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKCAJAIO_01892	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase
HKCAJAIO_01893	2.43e-47	-	-	-	S	-	-	-	MORN repeat protein
HKCAJAIO_01894	2.29e-106	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKCAJAIO_01895	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKCAJAIO_01896	3.91e-109	flaR	-	-	F	-	-	-	topology modulation protein
HKCAJAIO_01897	3.14e-244	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKCAJAIO_01898	3.96e-253	-	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	Involved in molybdopterin and thiamine biosynthesis, family 2
HKCAJAIO_01899	7.94e-69	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_01900	1.46e-190	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_01902	7.46e-200	-	-	-	K	ko:K20373,ko:K20374	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
HKCAJAIO_01903	0.0	-	-	-	KLT	-	-	-	serine threonine protein kinase
HKCAJAIO_01904	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
HKCAJAIO_01905	3.79e-16	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
HKCAJAIO_01906	4.66e-165	Z012_04635	-	-	K	-	-	-	sequence-specific DNA binding
HKCAJAIO_01908	9.82e-21	-	-	-	C	ko:K06871	-	ko00000	Radical SAM
HKCAJAIO_01909	1.85e-243	-	-	-	C	ko:K06871	-	ko00000	Radical SAM
HKCAJAIO_01910	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HKCAJAIO_01911	5.53e-79	-	-	-	K	-	-	-	sequence-specific DNA binding
HKCAJAIO_01912	1.59e-19	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKCAJAIO_01913	2.67e-53	-	-	-	L	-	-	-	Replication initiation factor
HKCAJAIO_01914	2.81e-137	-	-	-	L	-	-	-	Replication initiation factor
HKCAJAIO_01915	1.95e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
HKCAJAIO_01916	6.11e-278	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKCAJAIO_01918	3.74e-303	rarA	-	-	L	ko:K07478	-	ko00000	ATPase related to the helicase subunit of the Holliday junction resolvase
HKCAJAIO_01919	1.73e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKCAJAIO_01920	3.4e-59	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKCAJAIO_01921	8.4e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKCAJAIO_01922	2.7e-62	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKCAJAIO_01923	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HKCAJAIO_01924	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKCAJAIO_01925	7.68e-20	-	-	-	-	-	-	-	-
HKCAJAIO_01926	1.31e-118	-	-	-	K	-	-	-	acetyltransferase
HKCAJAIO_01927	5.13e-149	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKCAJAIO_01928	4.85e-189	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKCAJAIO_01929	1.53e-215	XK27_01785	-	-	S	-	-	-	cog cog1284
HKCAJAIO_01930	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKCAJAIO_01932	6.78e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKCAJAIO_01933	6.96e-65	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HKCAJAIO_01934	4.02e-80	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HKCAJAIO_01935	2.66e-44	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HKCAJAIO_01936	4.33e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HKCAJAIO_01937	1.22e-26	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKCAJAIO_01939	1.03e-27	yegS	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	lipid kinase activity
HKCAJAIO_01940	8.43e-124	-	-	-	S	-	-	-	Hydrophobic domain protein
HKCAJAIO_01942	7.98e-45	ytgB	-	-	S	-	-	-	Membrane
HKCAJAIO_01943	1.88e-131	-	-	-	-	-	-	-	-
HKCAJAIO_01944	7.53e-33	-	-	-	S	-	-	-	Small integral membrane protein
HKCAJAIO_01945	4.11e-104	-	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKCAJAIO_01946	5.78e-35	-	-	-	K	-	-	-	CsbD-like
HKCAJAIO_01947	4.09e-123	XK27_06885	-	-	L	-	-	-	hydrolase
HKCAJAIO_01948	2.9e-18	XK27_06885	-	-	L	-	-	-	hydrolase
HKCAJAIO_01949	7.54e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HKCAJAIO_01950	1.3e-26	-	-	-	K	ko:K10947	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HKCAJAIO_01951	4.32e-33	-	-	-	K	ko:K10947	-	ko00000,ko03000	negative regulation of transcription, DNA-templated
HKCAJAIO_01952	1.91e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HKCAJAIO_01953	1.58e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HKCAJAIO_01954	7.22e-121	-	-	-	S	-	-	-	Putative adhesin
HKCAJAIO_01955	5.13e-270	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HKCAJAIO_01956	3.98e-124	XK27_06935	-	-	K	-	-	-	transcriptional regulator
HKCAJAIO_01957	7.97e-73	XK27_04840	-	-	M	ko:K08987	-	ko00000	Membrane
HKCAJAIO_01958	2.05e-09	-	-	-	-	-	-	-	-
HKCAJAIO_01959	5.92e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKCAJAIO_01960	3.05e-63	WQ51_01655	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKCAJAIO_01961	1.29e-312	dnaC	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKCAJAIO_01962	1.24e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HKCAJAIO_01963	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKCAJAIO_01964	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKCAJAIO_01965	1.46e-101	-	-	-	F	-	-	-	NUDIX domain
HKCAJAIO_01966	9.38e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKCAJAIO_01967	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HKCAJAIO_01968	1.41e-125	isaA	-	-	M	-	-	-	Immunodominant staphylococcal antigen A
HKCAJAIO_01969	1.37e-122	lytE	-	-	M	-	-	-	LysM domain protein
HKCAJAIO_01970	1.73e-176	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKCAJAIO_01971	2.6e-195	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKCAJAIO_01972	4.68e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKCAJAIO_01973	7.67e-118	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKCAJAIO_01974	8.84e-185	ymfM	-	-	S	ko:K15539	-	ko00000	sequence-specific DNA binding
HKCAJAIO_01975	1.88e-309	ymfH	-	-	S	-	-	-	Peptidase M16
HKCAJAIO_01976	1.06e-299	albE	-	-	S	-	-	-	Peptidase M16
HKCAJAIO_01977	5.21e-61	yaaA	-	-	S	-	-	-	S4 domain protein YaaA
HKCAJAIO_01978	9.13e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKCAJAIO_01979	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKCAJAIO_01980	1.66e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HKCAJAIO_01981	9.73e-196	XK27_10395	-	-	S	-	-	-	membrane
HKCAJAIO_01982	0.0	ykpA	-	-	S	-	-	-	abc transporter atp-binding protein
HKCAJAIO_01983	0.0	XK27_10405	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKCAJAIO_01987	3.66e-155	yveI	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKCAJAIO_01988	1.79e-111	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKCAJAIO_01989	2.58e-261	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HKCAJAIO_01990	7.94e-173	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family