ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LKMAKOFG_00002 6.84e-43 - - - - - - - -
LKMAKOFG_00003 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LKMAKOFG_00004 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LKMAKOFG_00005 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
LKMAKOFG_00006 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LKMAKOFG_00007 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LKMAKOFG_00008 4.29e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKMAKOFG_00009 5.84e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LKMAKOFG_00010 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LKMAKOFG_00011 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LKMAKOFG_00012 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LKMAKOFG_00013 8.31e-274 pbpX - - V - - - Beta-lactamase
LKMAKOFG_00014 3.06e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LKMAKOFG_00015 4.64e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LKMAKOFG_00016 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKMAKOFG_00017 5.76e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LKMAKOFG_00018 3.14e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
LKMAKOFG_00019 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
LKMAKOFG_00020 3.51e-165 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LKMAKOFG_00021 1.01e-310 ymfH - - S - - - zinc protease
LKMAKOFG_00022 5.34e-305 albE - - S - - - Peptidase M16
LKMAKOFG_00023 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LKMAKOFG_00024 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_00025 3.16e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_00026 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_00027 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LKMAKOFG_00028 6.32e-42 - - - S - - - YlzJ-like protein
LKMAKOFG_00029 1.86e-165 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LKMAKOFG_00030 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKMAKOFG_00031 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LKMAKOFG_00032 5.72e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LKMAKOFG_00033 2.36e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LKMAKOFG_00034 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LKMAKOFG_00035 1.35e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LKMAKOFG_00036 2.17e-56 ymxH - - S - - - YlmC YmxH family
LKMAKOFG_00037 5.91e-299 mlpA - - S - - - Belongs to the peptidase M16 family
LKMAKOFG_00038 9.69e-219 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LKMAKOFG_00039 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LKMAKOFG_00040 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LKMAKOFG_00041 2.6e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LKMAKOFG_00042 2.99e-220 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LKMAKOFG_00043 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LKMAKOFG_00044 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LKMAKOFG_00045 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LKMAKOFG_00046 6.16e-63 ylxQ - - J - - - ribosomal protein
LKMAKOFG_00047 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LKMAKOFG_00048 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LKMAKOFG_00049 1.9e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LKMAKOFG_00050 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKMAKOFG_00051 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LKMAKOFG_00052 9.41e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LKMAKOFG_00053 2.57e-272 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LKMAKOFG_00054 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LKMAKOFG_00055 7.76e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LKMAKOFG_00056 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LKMAKOFG_00057 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LKMAKOFG_00058 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LKMAKOFG_00059 7.07e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LKMAKOFG_00060 5.85e-94 ylxL - - - - - - -
LKMAKOFG_00061 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKMAKOFG_00062 8.2e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LKMAKOFG_00063 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LKMAKOFG_00064 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LKMAKOFG_00065 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LKMAKOFG_00066 4.97e-249 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LKMAKOFG_00067 7.73e-201 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LKMAKOFG_00068 3.23e-249 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LKMAKOFG_00069 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKMAKOFG_00070 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LKMAKOFG_00071 2.84e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LKMAKOFG_00072 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LKMAKOFG_00073 6.02e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LKMAKOFG_00074 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LKMAKOFG_00075 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LKMAKOFG_00076 3.03e-244 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LKMAKOFG_00077 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKMAKOFG_00078 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LKMAKOFG_00079 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LKMAKOFG_00080 5.15e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
LKMAKOFG_00081 1.1e-262 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
LKMAKOFG_00082 1.98e-88 ylxF - - S - - - MgtE intracellular N domain
LKMAKOFG_00083 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LKMAKOFG_00084 2.11e-308 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LKMAKOFG_00085 3.96e-122 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LKMAKOFG_00086 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LKMAKOFG_00087 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LKMAKOFG_00088 1.02e-48 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
LKMAKOFG_00089 1.03e-96 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LKMAKOFG_00090 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LKMAKOFG_00091 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LKMAKOFG_00092 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LKMAKOFG_00093 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LKMAKOFG_00094 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LKMAKOFG_00095 3.83e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LKMAKOFG_00096 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKMAKOFG_00097 3.11e-217 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LKMAKOFG_00098 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LKMAKOFG_00099 5.8e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LKMAKOFG_00100 4.88e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LKMAKOFG_00101 0.0 ylqG - - - - - - -
LKMAKOFG_00102 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKMAKOFG_00103 5.09e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LKMAKOFG_00104 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LKMAKOFG_00105 1.63e-175 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LKMAKOFG_00106 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LKMAKOFG_00107 1.39e-79 ylqD - - S - - - YlqD protein
LKMAKOFG_00108 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LKMAKOFG_00109 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LKMAKOFG_00110 1.47e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LKMAKOFG_00111 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LKMAKOFG_00112 2.91e-180 - - - S - - - Phosphotransferase enzyme family
LKMAKOFG_00113 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LKMAKOFG_00114 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LKMAKOFG_00115 3.02e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LKMAKOFG_00116 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKMAKOFG_00117 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LKMAKOFG_00118 3.76e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKMAKOFG_00119 3.14e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LKMAKOFG_00120 1.26e-120 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LKMAKOFG_00121 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LKMAKOFG_00122 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LKMAKOFG_00123 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LKMAKOFG_00124 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LKMAKOFG_00125 3.65e-78 yloU - - S - - - protein conserved in bacteria
LKMAKOFG_00126 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LKMAKOFG_00127 2.06e-150 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LKMAKOFG_00128 3.42e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LKMAKOFG_00129 2.08e-209 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LKMAKOFG_00130 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LKMAKOFG_00131 4.1e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LKMAKOFG_00132 1.52e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LKMAKOFG_00133 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LKMAKOFG_00134 7.89e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LKMAKOFG_00135 2.89e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKMAKOFG_00136 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKMAKOFG_00137 8.87e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LKMAKOFG_00138 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LKMAKOFG_00139 4.03e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LKMAKOFG_00140 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LKMAKOFG_00141 2.14e-198 yloC - - S - - - stress-induced protein
LKMAKOFG_00142 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LKMAKOFG_00143 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LKMAKOFG_00144 4.41e-106 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LKMAKOFG_00145 1.19e-186 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LKMAKOFG_00146 5.9e-185 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LKMAKOFG_00147 1.94e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LKMAKOFG_00148 6.17e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LKMAKOFG_00149 8.54e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
LKMAKOFG_00150 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LKMAKOFG_00152 1.05e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LKMAKOFG_00153 3.66e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LKMAKOFG_00154 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LKMAKOFG_00155 2.13e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LKMAKOFG_00156 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LKMAKOFG_00157 1.26e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LKMAKOFG_00158 1.1e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LKMAKOFG_00159 5.99e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LKMAKOFG_00160 1.98e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LKMAKOFG_00161 2.21e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LKMAKOFG_00162 5.35e-216 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LKMAKOFG_00163 1.24e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LKMAKOFG_00164 1.21e-82 ylyA - - T - - - COG1734 DnaK suppressor protein
LKMAKOFG_00165 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LKMAKOFG_00166 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LKMAKOFG_00167 2.49e-181 ylmH - - S - - - conserved protein, contains S4-like domain
LKMAKOFG_00168 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LKMAKOFG_00169 4.61e-85 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LKMAKOFG_00170 3.68e-161 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LKMAKOFG_00171 1.16e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LKMAKOFG_00172 7.13e-52 ylmC - - S - - - sporulation protein
LKMAKOFG_00173 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
LKMAKOFG_00174 1.97e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LKMAKOFG_00175 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKMAKOFG_00176 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKMAKOFG_00177 3.91e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LKMAKOFG_00178 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
LKMAKOFG_00179 7.47e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LKMAKOFG_00180 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LKMAKOFG_00181 2.67e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LKMAKOFG_00182 2.26e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LKMAKOFG_00183 3.29e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LKMAKOFG_00184 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LKMAKOFG_00185 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LKMAKOFG_00186 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LKMAKOFG_00187 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LKMAKOFG_00188 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LKMAKOFG_00189 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LKMAKOFG_00190 2.4e-68 ftsL - - D - - - Essential cell division protein
LKMAKOFG_00191 4.08e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LKMAKOFG_00192 1.78e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LKMAKOFG_00193 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LKMAKOFG_00194 9.74e-210 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKMAKOFG_00195 1.09e-114 ylbP - - K - - - n-acetyltransferase
LKMAKOFG_00196 3.13e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LKMAKOFG_00197 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LKMAKOFG_00198 3.3e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LKMAKOFG_00199 3.02e-294 ylbM - - S - - - Belongs to the UPF0348 family
LKMAKOFG_00200 8.8e-240 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LKMAKOFG_00201 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LKMAKOFG_00202 4.14e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LKMAKOFG_00203 8.3e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LKMAKOFG_00204 1.09e-115 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LKMAKOFG_00205 3.94e-57 ylbG - - S - - - UPF0298 protein
LKMAKOFG_00206 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
LKMAKOFG_00207 1.73e-48 ylbE - - S - - - YlbE-like protein
LKMAKOFG_00208 8.47e-87 ylbD - - S - - - Putative coat protein
LKMAKOFG_00209 1.09e-252 ylbC - - S - - - protein with SCP PR1 domains
LKMAKOFG_00210 9.59e-96 ylbB - - T - - - COG0517 FOG CBS domain
LKMAKOFG_00211 4.12e-79 ylbA - - S - - - YugN-like family
LKMAKOFG_00212 3.59e-212 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LKMAKOFG_00213 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LKMAKOFG_00214 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LKMAKOFG_00215 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKMAKOFG_00216 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LKMAKOFG_00217 2.07e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKMAKOFG_00218 3.47e-214 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LKMAKOFG_00219 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LKMAKOFG_00220 8.59e-272 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LKMAKOFG_00221 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
LKMAKOFG_00222 5.18e-221 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LKMAKOFG_00223 1.23e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LKMAKOFG_00224 2.7e-313 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LKMAKOFG_00225 5.45e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKMAKOFG_00226 1.95e-45 ylaI - - S - - - protein conserved in bacteria
LKMAKOFG_00227 2.44e-65 - - - S - - - YlaH-like protein
LKMAKOFG_00228 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LKMAKOFG_00229 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
LKMAKOFG_00230 2.3e-61 ylaE - - - - - - -
LKMAKOFG_00232 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LKMAKOFG_00233 6.98e-104 ykzC - - S - - - Acetyltransferase (GNAT) family
LKMAKOFG_00234 4.51e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LKMAKOFG_00235 3.33e-33 ykzI - - - - - - -
LKMAKOFG_00236 8.15e-155 yktB - - S - - - Belongs to the UPF0637 family
LKMAKOFG_00237 3.83e-56 yktA - - S - - - Belongs to the UPF0223 family
LKMAKOFG_00238 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LKMAKOFG_00239 3.26e-188 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LKMAKOFG_00240 6.84e-60 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
LKMAKOFG_00241 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKMAKOFG_00242 2.08e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKMAKOFG_00243 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKMAKOFG_00244 6.68e-262 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKMAKOFG_00245 5.3e-264 - - - V - - - Beta-lactamase
LKMAKOFG_00246 0.0 - - - IQ - - - Phosphopantetheine attachment site
LKMAKOFG_00247 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_00248 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_00249 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_00250 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_00251 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
LKMAKOFG_00252 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_00253 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKMAKOFG_00254 1.32e-132 ykyA - - L - - - Putative cell-wall binding lipoprotein
LKMAKOFG_00255 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LKMAKOFG_00256 1.14e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LKMAKOFG_00257 1.45e-185 ykrA - - S - - - hydrolases of the HAD superfamily
LKMAKOFG_00258 1.28e-41 ykzG - - S - - - Belongs to the UPF0356 family
LKMAKOFG_00259 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LKMAKOFG_00260 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LKMAKOFG_00261 2.78e-147 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LKMAKOFG_00262 2.51e-195 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
LKMAKOFG_00263 2.39e-312 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LKMAKOFG_00264 7.46e-59 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
LKMAKOFG_00265 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LKMAKOFG_00266 4.47e-18 - - - S - - - Uncharacterized protein YkpC
LKMAKOFG_00267 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LKMAKOFG_00268 7.59e-215 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKMAKOFG_00269 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKMAKOFG_00270 1.5e-49 ykoA - - - - - - -
LKMAKOFG_00271 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LKMAKOFG_00272 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LKMAKOFG_00273 1.93e-213 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LKMAKOFG_00274 9.28e-170 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_00275 4.23e-269 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LKMAKOFG_00276 2.38e-157 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_00277 3.31e-245 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LKMAKOFG_00278 3.27e-140 yknW - - S - - - Yip1 domain
LKMAKOFG_00279 2.06e-46 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LKMAKOFG_00280 7.17e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LKMAKOFG_00281 1.31e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LKMAKOFG_00282 3.38e-310 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LKMAKOFG_00283 1.41e-240 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKMAKOFG_00284 3.89e-139 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LKMAKOFG_00285 4.18e-217 yknT - - - ko:K06437 - ko00000 -
LKMAKOFG_00286 3.04e-126 rok - - K - - - Repressor of ComK
LKMAKOFG_00287 2.24e-101 ykuV - - CO - - - thiol-disulfide
LKMAKOFG_00288 1.42e-177 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LKMAKOFG_00289 8.78e-52 ykuS - - S - - - Belongs to the UPF0180 family
LKMAKOFG_00290 6.57e-275 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LKMAKOFG_00291 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LKMAKOFG_00292 2.16e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
LKMAKOFG_00293 2.37e-220 ykuO - - - - - - -
LKMAKOFG_00294 3.69e-116 ykuN - - C ko:K03839 - ko00000 Flavodoxin
LKMAKOFG_00295 1.32e-215 ccpC - - K - - - Transcriptional regulator
LKMAKOFG_00296 8.55e-99 ykuL - - S - - - CBS domain
LKMAKOFG_00297 3.09e-35 ykzF - - S - - - Antirepressor AbbA
LKMAKOFG_00298 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
LKMAKOFG_00299 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
LKMAKOFG_00300 7.72e-297 ykuI - - T - - - Diguanylate phosphodiesterase
LKMAKOFG_00302 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_00303 3.01e-196 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
LKMAKOFG_00304 2.55e-116 ykuD - - S - - - protein conserved in bacteria
LKMAKOFG_00305 4.6e-308 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_00306 5.07e-108 ykyB - - S - - - YkyB-like protein
LKMAKOFG_00307 2.63e-211 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LKMAKOFG_00308 6.38e-15 - - - - - - - -
LKMAKOFG_00309 1.62e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LKMAKOFG_00310 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_00311 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LKMAKOFG_00312 3.5e-160 ykwD - - J - - - protein with SCP PR1 domains
LKMAKOFG_00313 1.4e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LKMAKOFG_00314 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKMAKOFG_00315 3.53e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
LKMAKOFG_00316 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_00317 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LKMAKOFG_00318 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LKMAKOFG_00319 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_00320 4.61e-198 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LKMAKOFG_00321 1.01e-224 ykvZ - - K - - - Transcriptional regulator
LKMAKOFG_00323 1.35e-262 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LKMAKOFG_00324 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LKMAKOFG_00325 8.57e-114 stoA - - CO - - - thiol-disulfide
LKMAKOFG_00326 7.63e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKMAKOFG_00327 7.21e-143 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
LKMAKOFG_00328 7.17e-39 - - - - - - - -
LKMAKOFG_00329 5.43e-35 ykvS - - S - - - protein conserved in bacteria
LKMAKOFG_00330 3.48e-58 ykvR - - S - - - Protein of unknown function (DUF3219)
LKMAKOFG_00331 2.57e-170 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LKMAKOFG_00332 9.98e-74 - - - K - - - HxlR-like helix-turn-helix
LKMAKOFG_00333 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LKMAKOFG_00334 8.4e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LKMAKOFG_00335 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
LKMAKOFG_00336 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LKMAKOFG_00337 1.8e-251 - - - - - - - -
LKMAKOFG_00338 1.73e-228 ykvI - - S - - - membrane
LKMAKOFG_00339 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LKMAKOFG_00340 2.96e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LKMAKOFG_00341 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LKMAKOFG_00342 3.91e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
LKMAKOFG_00343 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LKMAKOFG_00345 2.05e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LKMAKOFG_00346 4.52e-147 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LKMAKOFG_00347 4.69e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LKMAKOFG_00348 1.51e-286 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LKMAKOFG_00349 8.56e-290 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LKMAKOFG_00350 2.61e-189 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKMAKOFG_00351 2.44e-287 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LKMAKOFG_00352 4.44e-251 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LKMAKOFG_00354 1.08e-112 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKMAKOFG_00355 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_00356 1.52e-240 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LKMAKOFG_00357 3.07e-32 ykzE - - - - - - -
LKMAKOFG_00358 6.05e-148 - - - S - - - Protein of unknown function (DUF421)
LKMAKOFG_00359 4.63e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
LKMAKOFG_00360 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LKMAKOFG_00361 6.86e-163 ykrK - - S - - - Domain of unknown function (DUF1836)
LKMAKOFG_00362 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LKMAKOFG_00363 2.53e-250 ykrI - - S - - - Anti-sigma factor N-terminus
LKMAKOFG_00364 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKMAKOFG_00365 1.18e-172 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LKMAKOFG_00366 1.43e-131 ykoX - - S - - - membrane-associated protein
LKMAKOFG_00367 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LKMAKOFG_00368 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LKMAKOFG_00369 3.81e-129 ykoP - - G - - - polysaccharide deacetylase
LKMAKOFG_00370 1.98e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
LKMAKOFG_00371 5.25e-37 ykoL - - - - - - -
LKMAKOFG_00372 1.11e-23 - - - - - - - -
LKMAKOFG_00373 1.23e-69 tnrA - - K - - - transcriptional
LKMAKOFG_00374 8.66e-310 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LKMAKOFG_00376 6.28e-310 ydhD - - M - - - Glycosyl hydrolase
LKMAKOFG_00377 6.62e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LKMAKOFG_00378 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_00379 4.41e-169 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LKMAKOFG_00380 1.05e-188 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKMAKOFG_00381 5.2e-226 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKMAKOFG_00382 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LKMAKOFG_00383 4.72e-154 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LKMAKOFG_00384 5.66e-277 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_00385 7.85e-179 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
LKMAKOFG_00386 4.6e-271 - - - M - - - Glycosyl transferase family 2
LKMAKOFG_00388 6.7e-82 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LKMAKOFG_00389 3.2e-91 ohrB - - O - - - Organic hydroperoxide resistance protein
LKMAKOFG_00390 1.2e-111 ohrR - - K - - - COG1846 Transcriptional regulators
LKMAKOFG_00391 6.87e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
LKMAKOFG_00392 1.37e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LKMAKOFG_00393 1.77e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKMAKOFG_00394 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LKMAKOFG_00395 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LKMAKOFG_00396 4.09e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LKMAKOFG_00397 1.75e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKMAKOFG_00398 3.06e-120 ykhA - - I - - - Acyl-CoA hydrolase
LKMAKOFG_00399 3.44e-203 ykgA - - E - - - Amidinotransferase
LKMAKOFG_00400 8.42e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LKMAKOFG_00401 2.31e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_00402 5.37e-218 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKMAKOFG_00403 6.37e-257 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LKMAKOFG_00404 2.29e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LKMAKOFG_00405 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LKMAKOFG_00406 5.55e-244 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_00407 1.33e-226 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKMAKOFG_00408 1.39e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKMAKOFG_00409 4.18e-198 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
LKMAKOFG_00411 0.0 yubD - - P - - - Major Facilitator Superfamily
LKMAKOFG_00412 1.07e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKMAKOFG_00414 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKMAKOFG_00415 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LKMAKOFG_00416 4.3e-228 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LKMAKOFG_00417 8.24e-306 steT - - E ko:K03294 - ko00000 amino acid
LKMAKOFG_00418 1.2e-140 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
LKMAKOFG_00419 1.22e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
LKMAKOFG_00420 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LKMAKOFG_00421 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
LKMAKOFG_00422 2.46e-215 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LKMAKOFG_00423 9.5e-52 xhlB - - S - - - SPP1 phage holin
LKMAKOFG_00424 3.87e-51 xhlA - - S - - - Haemolysin XhlA
LKMAKOFG_00425 5.43e-179 xepA - - - - - - -
LKMAKOFG_00426 3.25e-40 xkdX - - - - - - -
LKMAKOFG_00428 4.1e-86 - - - - - - - -
LKMAKOFG_00429 8.92e-38 - - - - - - - -
LKMAKOFG_00430 3.37e-111 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LKMAKOFG_00431 6.22e-212 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LKMAKOFG_00432 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
LKMAKOFG_00433 1.77e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
LKMAKOFG_00434 1.32e-206 xkdQ - - G - - - NLP P60 protein
LKMAKOFG_00435 3.8e-144 xkdP - - S - - - Lysin motif
LKMAKOFG_00436 3.42e-258 xkdO - - L - - - Transglycosylase SLT domain
LKMAKOFG_00437 4.69e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKMAKOFG_00438 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKMAKOFG_00439 3.58e-282 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
LKMAKOFG_00440 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKMAKOFG_00441 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
LKMAKOFG_00442 1.17e-146 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
LKMAKOFG_00443 1.63e-184 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LKMAKOFG_00444 1.4e-304 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
LKMAKOFG_00445 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LKMAKOFG_00446 8.67e-239 yvhJ - - K - - - Transcriptional regulator
LKMAKOFG_00447 2.94e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LKMAKOFG_00448 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LKMAKOFG_00449 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_00450 7.24e-203 degV - - S - - - protein conserved in bacteria
LKMAKOFG_00451 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LKMAKOFG_00452 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
LKMAKOFG_00453 6.79e-98 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LKMAKOFG_00454 5.47e-98 yvyF - - S - - - flagellar protein
LKMAKOFG_00455 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LKMAKOFG_00456 1.81e-104 yvyG - - NOU - - - FlgN protein
LKMAKOFG_00457 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LKMAKOFG_00458 1.2e-208 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LKMAKOFG_00459 3.98e-108 yviE - - - - - - -
LKMAKOFG_00460 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LKMAKOFG_00461 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LKMAKOFG_00462 9.98e-154 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LKMAKOFG_00463 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LKMAKOFG_00464 1.66e-87 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LKMAKOFG_00465 1.72e-09 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LKMAKOFG_00466 5.5e-89 - - - - - - - -
LKMAKOFG_00467 6.54e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LKMAKOFG_00468 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LKMAKOFG_00469 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LKMAKOFG_00470 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKMAKOFG_00471 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LKMAKOFG_00472 1.01e-157 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LKMAKOFG_00473 5e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LKMAKOFG_00474 1.16e-302 ywoF - - P - - - Right handed beta helix region
LKMAKOFG_00475 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LKMAKOFG_00476 2.47e-73 swrA - - S - - - Swarming motility protein
LKMAKOFG_00477 5.92e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKMAKOFG_00478 3.31e-235 - - - S - - - Psort location CytoplasmicMembrane, score
LKMAKOFG_00480 9.93e-18 - - - Q - - - thioesterase involved in non-ribosomal peptide biosynthesis
LKMAKOFG_00482 1.7e-297 yvkA - - P - - - -transporter
LKMAKOFG_00483 2.32e-144 yvkB - - K - - - Transcriptional regulator
LKMAKOFG_00484 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
LKMAKOFG_00485 2.59e-45 csbA - - S - - - protein conserved in bacteria
LKMAKOFG_00486 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LKMAKOFG_00487 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LKMAKOFG_00488 3.29e-43 yvkN - - - - - - -
LKMAKOFG_00489 4.87e-66 yvlA - - - - - - -
LKMAKOFG_00490 3.2e-218 yvlB - - S - - - Putative adhesin
LKMAKOFG_00491 4.01e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LKMAKOFG_00492 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
LKMAKOFG_00493 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
LKMAKOFG_00494 3.63e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LKMAKOFG_00495 2.13e-171 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
LKMAKOFG_00496 9.42e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LKMAKOFG_00497 2.25e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LKMAKOFG_00498 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LKMAKOFG_00499 1.24e-193 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LKMAKOFG_00500 2.33e-157 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LKMAKOFG_00501 3.57e-112 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LKMAKOFG_00502 4.16e-177 yvpB - - NU - - - protein conserved in bacteria
LKMAKOFG_00503 4.95e-269 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LKMAKOFG_00504 7.47e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LKMAKOFG_00505 3.54e-295 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LKMAKOFG_00506 2.26e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LKMAKOFG_00507 1.63e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LKMAKOFG_00508 3.79e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LKMAKOFG_00509 1.38e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LKMAKOFG_00510 1.35e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LKMAKOFG_00511 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LKMAKOFG_00512 1.14e-157 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_00513 1.12e-244 sasA - - T - - - Histidine kinase
LKMAKOFG_00514 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
LKMAKOFG_00515 4.64e-202 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LKMAKOFG_00516 3.13e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LKMAKOFG_00517 1.22e-111 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKMAKOFG_00518 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LKMAKOFG_00519 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LKMAKOFG_00520 7.8e-43 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LKMAKOFG_00521 2.44e-166 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LKMAKOFG_00522 3.23e-49 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LKMAKOFG_00523 8.09e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
LKMAKOFG_00524 2.26e-104 - - - M - - - Ribonuclease
LKMAKOFG_00525 4.85e-232 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKMAKOFG_00526 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LKMAKOFG_00527 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LKMAKOFG_00528 5.31e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
LKMAKOFG_00529 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LKMAKOFG_00530 0.0 - - - EGP - - - Sugar (and other) transporter
LKMAKOFG_00531 7.36e-273 yraM - - S - - - PrpF protein
LKMAKOFG_00532 1.93e-209 yraN - - K - - - Transcriptional regulator
LKMAKOFG_00533 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LKMAKOFG_00534 3.17e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
LKMAKOFG_00535 4.05e-285 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
LKMAKOFG_00536 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LKMAKOFG_00538 1.31e-45 - - - - - - - -
LKMAKOFG_00539 1.35e-304 - - - I - - - Pfam Lipase (class 3)
LKMAKOFG_00541 6.45e-47 - - - I - - - Pfam Lipase (class 3)
LKMAKOFG_00542 8.52e-51 - - - S - - - Protein of unknown function (DUF1433)
LKMAKOFG_00544 1.01e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LKMAKOFG_00545 1.9e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKMAKOFG_00546 2.06e-143 yyaS - - S ko:K07149 - ko00000 Membrane
LKMAKOFG_00547 4.68e-126 ywjB - - H - - - RibD C-terminal domain
LKMAKOFG_00548 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LKMAKOFG_00549 5.95e-101 - - - K ko:K19417 - ko00000,ko03000 transcriptional
LKMAKOFG_00550 1.17e-155 epsA - - M ko:K19420 - ko00000 biosynthesis protein
LKMAKOFG_00551 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LKMAKOFG_00552 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LKMAKOFG_00553 2.49e-277 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
LKMAKOFG_00554 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKMAKOFG_00555 3e-273 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LKMAKOFG_00556 1.71e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
LKMAKOFG_00557 5.37e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LKMAKOFG_00558 7.76e-259 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
LKMAKOFG_00559 1.48e-249 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKMAKOFG_00560 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKMAKOFG_00561 4.53e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LKMAKOFG_00562 3.59e-75 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LKMAKOFG_00563 3.7e-280 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LKMAKOFG_00564 7.81e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
LKMAKOFG_00565 4.01e-44 yvfG - - S - - - YvfG protein
LKMAKOFG_00566 2.78e-310 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LKMAKOFG_00567 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LKMAKOFG_00568 4.22e-154 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LKMAKOFG_00569 1.52e-282 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKMAKOFG_00570 1.02e-171 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKMAKOFG_00571 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LKMAKOFG_00572 1.44e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LKMAKOFG_00573 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LKMAKOFG_00574 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LKMAKOFG_00575 6.34e-194 gntR - - K - - - RpiR family transcriptional regulator
LKMAKOFG_00576 4.41e-215 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LKMAKOFG_00577 4.06e-86 - - - S ko:K07149 - ko00000 Membrane
LKMAKOFG_00578 1.51e-232 yhjM - - K - - - Transcriptional regulator
LKMAKOFG_00579 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKMAKOFG_00580 2.59e-203 yvbV - - EG - - - EamA-like transporter family
LKMAKOFG_00581 1.51e-200 yvbU - - K - - - Transcriptional regulator
LKMAKOFG_00583 5.33e-243 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKMAKOFG_00584 4.51e-260 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LKMAKOFG_00585 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKMAKOFG_00587 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKMAKOFG_00588 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKMAKOFG_00589 1.62e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LKMAKOFG_00590 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LKMAKOFG_00591 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LKMAKOFG_00592 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LKMAKOFG_00593 1.03e-304 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
LKMAKOFG_00594 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKMAKOFG_00595 4.83e-278 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LKMAKOFG_00596 1.08e-217 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
LKMAKOFG_00597 1.08e-288 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LKMAKOFG_00598 3.45e-186 - - - M - - - Protein involved in cellulose biosynthesis
LKMAKOFG_00599 2.89e-185 - - - C - - - WbqC-like protein family
LKMAKOFG_00600 4.49e-162 - - - S - - - GlcNAc-PI de-N-acetylase
LKMAKOFG_00601 3.98e-228 - - - - - - - -
LKMAKOFG_00602 3.12e-269 - - - EGP - - - Major facilitator Superfamily
LKMAKOFG_00603 1.29e-105 yvbK - - K - - - acetyltransferase
LKMAKOFG_00604 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LKMAKOFG_00605 1.47e-154 yvbI - - M - - - Membrane
LKMAKOFG_00606 1.88e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LKMAKOFG_00607 4.11e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LKMAKOFG_00608 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKMAKOFG_00609 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKMAKOFG_00610 1.32e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKMAKOFG_00611 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKMAKOFG_00612 2.81e-123 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LKMAKOFG_00613 1.17e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LKMAKOFG_00614 4.83e-146 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKMAKOFG_00615 1.09e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LKMAKOFG_00616 2.09e-144 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LKMAKOFG_00617 5.4e-162 spaF - - V ko:K01990,ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_00618 1.47e-158 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LKMAKOFG_00619 5.63e-178 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LKMAKOFG_00620 1.34e-158 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
LKMAKOFG_00621 0.0 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
LKMAKOFG_00622 2.44e-69 yvaP - - K - - - transcriptional
LKMAKOFG_00623 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LKMAKOFG_00624 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
LKMAKOFG_00625 1.64e-47 yvzC - - K - - - transcriptional
LKMAKOFG_00626 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LKMAKOFG_00627 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LKMAKOFG_00628 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LKMAKOFG_00629 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LKMAKOFG_00631 5.89e-66 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LKMAKOFG_00632 1.13e-179 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_00633 1.81e-202 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
LKMAKOFG_00634 1.83e-129 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LKMAKOFG_00635 2.3e-165 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LKMAKOFG_00636 1.44e-187 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LKMAKOFG_00637 2.09e-156 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKMAKOFG_00638 3.35e-155 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKMAKOFG_00639 7.4e-180 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKMAKOFG_00640 1.76e-232 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKMAKOFG_00641 7.12e-62 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
LKMAKOFG_00642 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKMAKOFG_00643 1.03e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKMAKOFG_00644 3.36e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LKMAKOFG_00645 3.28e-63 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
LKMAKOFG_00646 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
LKMAKOFG_00647 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LKMAKOFG_00648 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LKMAKOFG_00649 6.43e-138 bdbD - - O - - - Thioredoxin
LKMAKOFG_00650 7.48e-96 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LKMAKOFG_00651 8.08e-192 - - - S - - - Metallo-peptidase family M12
LKMAKOFG_00652 6.36e-130 yvgT - - S - - - membrane
LKMAKOFG_00653 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKMAKOFG_00654 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LKMAKOFG_00655 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LKMAKOFG_00656 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LKMAKOFG_00657 3.8e-111 yvgO - - - - - - -
LKMAKOFG_00658 1.77e-200 yvgN - - S - - - reductase
LKMAKOFG_00659 7.38e-255 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LKMAKOFG_00660 3e-250 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LKMAKOFG_00661 1.66e-218 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LKMAKOFG_00662 1.67e-250 - - - T - - - Histidine kinase
LKMAKOFG_00663 4.32e-148 yfiK - - K - - - Regulator
LKMAKOFG_00664 6.41e-122 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LKMAKOFG_00665 4.78e-179 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
LKMAKOFG_00666 4.05e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
LKMAKOFG_00667 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
LKMAKOFG_00668 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LKMAKOFG_00669 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
LKMAKOFG_00670 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LKMAKOFG_00671 1.05e-226 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKMAKOFG_00672 3.29e-238 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_00673 2.27e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_00674 1.97e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKMAKOFG_00675 6.6e-86 yvrL - - S - - - Regulatory protein YrvL
LKMAKOFG_00676 1.08e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LKMAKOFG_00677 1.88e-21 - - - S - - - YvrJ protein family
LKMAKOFG_00678 7.6e-133 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
LKMAKOFG_00679 1.67e-50 - - - - - - - -
LKMAKOFG_00680 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_00681 0.0 yvrG - - T - - - Histidine kinase
LKMAKOFG_00682 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
LKMAKOFG_00683 1.01e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_00684 1.16e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LKMAKOFG_00685 2.19e-228 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_00686 5.74e-284 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LKMAKOFG_00687 2.66e-132 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LKMAKOFG_00688 6.8e-290 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_00689 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
LKMAKOFG_00690 3.96e-133 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LKMAKOFG_00691 1.91e-181 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LKMAKOFG_00692 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LKMAKOFG_00693 3.48e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_00694 3.4e-138 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_00695 2.93e-260 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
LKMAKOFG_00696 2.16e-244 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LKMAKOFG_00697 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LKMAKOFG_00698 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
LKMAKOFG_00699 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LKMAKOFG_00700 1.8e-200 yuxN - - K - - - Transcriptional regulator
LKMAKOFG_00701 2.68e-32 - - - - - - - -
LKMAKOFG_00702 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_00703 1.29e-163 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_00704 4.22e-304 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKMAKOFG_00705 6.84e-102 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LKMAKOFG_00706 2.49e-193 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_00707 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LKMAKOFG_00708 5.36e-60 - - - S - - - YusW-like protein
LKMAKOFG_00709 1.29e-192 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKMAKOFG_00710 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
LKMAKOFG_00711 6.96e-240 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LKMAKOFG_00712 4.14e-176 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
LKMAKOFG_00713 2.31e-201 - - - K - - - Transcriptional regulator
LKMAKOFG_00714 0.0 yusP - - P - - - Major facilitator superfamily
LKMAKOFG_00715 1.31e-89 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LKMAKOFG_00716 4.46e-72 yusN - - M - - - Coat F domain
LKMAKOFG_00717 2.64e-57 - - - - - - - -
LKMAKOFG_00718 1.26e-213 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LKMAKOFG_00719 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LKMAKOFG_00720 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LKMAKOFG_00721 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LKMAKOFG_00722 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LKMAKOFG_00723 4.16e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LKMAKOFG_00724 3.1e-55 yusG - - S - - - Protein of unknown function (DUF2553)
LKMAKOFG_00725 1.26e-81 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
LKMAKOFG_00726 1.64e-72 yusE - - CO - - - Thioredoxin
LKMAKOFG_00727 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
LKMAKOFG_00728 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LKMAKOFG_00729 2.96e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LKMAKOFG_00730 4.46e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
LKMAKOFG_00731 5.13e-84 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LKMAKOFG_00732 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LKMAKOFG_00733 1.23e-311 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LKMAKOFG_00734 5.44e-297 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LKMAKOFG_00735 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LKMAKOFG_00736 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LKMAKOFG_00737 1.46e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LKMAKOFG_00738 6.17e-104 yncE - - S - - - Protein of unknown function (DUF2691)
LKMAKOFG_00740 1.16e-48 - - - - - - - -
LKMAKOFG_00741 9.09e-260 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LKMAKOFG_00742 2.34e-85 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
LKMAKOFG_00744 7.48e-235 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LKMAKOFG_00745 1.28e-313 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LKMAKOFG_00746 6.14e-202 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKMAKOFG_00747 3.6e-209 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LKMAKOFG_00748 1.78e-204 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LKMAKOFG_00749 1.39e-171 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LKMAKOFG_00750 1.58e-263 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_00751 1.66e-216 bsn - - L - - - Ribonuclease
LKMAKOFG_00752 9.02e-295 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LKMAKOFG_00753 5.95e-302 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LKMAKOFG_00754 5.21e-275 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_00757 1.84e-12 xkdF3 - - L - - - Putative phage serine protease XkdF
LKMAKOFG_00758 5.58e-06 yqbD - - L - - - Putative phage serine protease XkdF
LKMAKOFG_00759 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
LKMAKOFG_00760 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LKMAKOFG_00761 3.04e-80 - - - S - - - phosphoglycolate phosphatase activity
LKMAKOFG_00762 1.8e-217 yunF - - S - - - Protein of unknown function DUF72
LKMAKOFG_00763 3.51e-185 yunE - - S ko:K07090 - ko00000 membrane transporter protein
LKMAKOFG_00764 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LKMAKOFG_00765 7.89e-167 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LKMAKOFG_00766 2.36e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LKMAKOFG_00767 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LKMAKOFG_00768 3.71e-62 yutD - - S - - - protein conserved in bacteria
LKMAKOFG_00769 2.67e-96 yutE - - S - - - Protein of unknown function DUF86
LKMAKOFG_00770 1.18e-179 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LKMAKOFG_00771 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LKMAKOFG_00772 6.3e-250 yutH - - S - - - Spore coat protein
LKMAKOFG_00773 8.26e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LKMAKOFG_00774 5.41e-250 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LKMAKOFG_00775 7.89e-216 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LKMAKOFG_00776 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
LKMAKOFG_00777 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LKMAKOFG_00778 1.1e-71 yuzD - - S - - - protein conserved in bacteria
LKMAKOFG_00779 8.47e-266 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LKMAKOFG_00780 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
LKMAKOFG_00781 1.49e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKMAKOFG_00782 2.25e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LKMAKOFG_00783 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LKMAKOFG_00784 1.49e-176 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_00785 8.37e-122 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
LKMAKOFG_00787 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
LKMAKOFG_00789 9.29e-157 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LKMAKOFG_00790 2.07e-93 - - - CP - - - Membrane
LKMAKOFG_00791 5.68e-40 - - - - - - - -
LKMAKOFG_00792 6.68e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LKMAKOFG_00794 4.19e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LKMAKOFG_00795 3.42e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LKMAKOFG_00796 1.41e-44 yuiB - - S - - - Putative membrane protein
LKMAKOFG_00797 1.99e-152 yuiC - - S - - - protein conserved in bacteria
LKMAKOFG_00798 8.29e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LKMAKOFG_00799 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LKMAKOFG_00800 1.16e-275 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
LKMAKOFG_00801 5.29e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LKMAKOFG_00802 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
LKMAKOFG_00803 1.04e-210 eSD - - S ko:K07017 - ko00000 Putative esterase
LKMAKOFG_00804 9.64e-169 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_00805 6.19e-283 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LKMAKOFG_00806 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
LKMAKOFG_00807 1.67e-221 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
LKMAKOFG_00808 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_00809 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
LKMAKOFG_00810 3.06e-171 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
LKMAKOFG_00811 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LKMAKOFG_00812 2.63e-166 yukF - - QT - - - Transcriptional regulator
LKMAKOFG_00813 6.65e-81 yukF - - QT - - - Transcriptional regulator
LKMAKOFG_00814 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
LKMAKOFG_00815 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
LKMAKOFG_00816 7.6e-274 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LKMAKOFG_00817 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LKMAKOFG_00818 0.0 yueB - - S - - - type VII secretion protein EsaA
LKMAKOFG_00819 1.33e-100 yueC - - S - - - Family of unknown function (DUF5383)
LKMAKOFG_00820 2.04e-169 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_00821 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
LKMAKOFG_00822 2.81e-31 - - - S - - - Protein of unknown function (DUF2642)
LKMAKOFG_00823 2.67e-238 yueF - - S - - - transporter activity
LKMAKOFG_00824 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
LKMAKOFG_00825 5.46e-51 yueH - - S - - - YueH-like protein
LKMAKOFG_00826 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
LKMAKOFG_00827 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LKMAKOFG_00828 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LKMAKOFG_00829 1.62e-294 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
LKMAKOFG_00830 7.31e-68 yuzC - - - - - - -
LKMAKOFG_00831 2.66e-11 - - - S - - - DegQ (SacQ) family
LKMAKOFG_00832 3.65e-124 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
LKMAKOFG_00834 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_00835 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_00836 4e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LKMAKOFG_00837 1.21e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
LKMAKOFG_00838 1.1e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKMAKOFG_00839 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKMAKOFG_00840 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKMAKOFG_00841 1.21e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKMAKOFG_00842 6.3e-90 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LKMAKOFG_00843 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LKMAKOFG_00845 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LKMAKOFG_00846 3.17e-237 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LKMAKOFG_00847 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_00848 1.43e-249 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LKMAKOFG_00849 6.58e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LKMAKOFG_00850 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LKMAKOFG_00851 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
LKMAKOFG_00852 5.29e-95 yuxK - - S - - - protein conserved in bacteria
LKMAKOFG_00853 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
LKMAKOFG_00854 2.25e-264 yuxJ - - EGP - - - Major facilitator superfamily
LKMAKOFG_00855 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
LKMAKOFG_00856 2.81e-88 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LKMAKOFG_00857 1.17e-288 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_00858 5.51e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LKMAKOFG_00859 4.97e-54 yugE - - S - - - Domain of unknown function (DUF1871)
LKMAKOFG_00860 3.31e-199 yugF - - I - - - Hydrolase
LKMAKOFG_00861 1.53e-108 alaR - - K - - - Transcriptional regulator
LKMAKOFG_00862 1.68e-266 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
LKMAKOFG_00863 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LKMAKOFG_00864 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LKMAKOFG_00865 2.24e-284 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
LKMAKOFG_00866 1.37e-291 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
LKMAKOFG_00867 3.59e-152 ycaC - - Q - - - Isochorismatase family
LKMAKOFG_00868 1.09e-130 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
LKMAKOFG_00869 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LKMAKOFG_00871 1.72e-94 yugN - - S - - - YugN-like family
LKMAKOFG_00872 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LKMAKOFG_00873 4.93e-35 mstX - - S - - - Membrane-integrating protein Mistic
LKMAKOFG_00874 1.24e-22 - - - - - - - -
LKMAKOFG_00875 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LKMAKOFG_00876 4.67e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LKMAKOFG_00877 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LKMAKOFG_00878 5.24e-101 yugU - - S - - - Uncharacterised protein family UPF0047
LKMAKOFG_00879 2.85e-242 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LKMAKOFG_00880 1.61e-55 - - - - - - - -
LKMAKOFG_00881 2.22e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LKMAKOFG_00882 6.29e-316 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKMAKOFG_00883 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKMAKOFG_00884 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKMAKOFG_00885 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LKMAKOFG_00886 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
LKMAKOFG_00887 3.18e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LKMAKOFG_00888 9.96e-251 yubA - - S - - - transporter activity
LKMAKOFG_00889 9.32e-187 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LKMAKOFG_00891 2.63e-69 yjcN - - - - - - -
LKMAKOFG_00892 9.53e-160 - - - G - - - Cupin
LKMAKOFG_00893 1.77e-283 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LKMAKOFG_00894 2.58e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKMAKOFG_00895 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LKMAKOFG_00896 2.03e-122 yuaB - - - - - - -
LKMAKOFG_00897 7.09e-125 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
LKMAKOFG_00898 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKMAKOFG_00899 1.74e-290 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LKMAKOFG_00900 6.79e-141 - - - S - - - MOSC domain
LKMAKOFG_00901 2.98e-104 yuaE - - S - - - DinB superfamily
LKMAKOFG_00902 5.6e-107 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LKMAKOFG_00903 7.57e-278 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LKMAKOFG_00904 4.9e-125 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LKMAKOFG_00908 2.71e-120 - - - K - - - Transcriptional regulator PadR-like family
LKMAKOFG_00909 4.36e-203 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
LKMAKOFG_00910 2.27e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKMAKOFG_00911 5.68e-280 - - - EGP - - - Transmembrane secretion effector
LKMAKOFG_00912 2.22e-34 - 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LKMAKOFG_00913 4.93e-138 yqeD - - S - - - SNARE associated Golgi protein
LKMAKOFG_00914 1.34e-179 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LKMAKOFG_00915 3.59e-178 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
LKMAKOFG_00917 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LKMAKOFG_00918 7.93e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LKMAKOFG_00919 2.95e-201 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKMAKOFG_00920 3.12e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LKMAKOFG_00921 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LKMAKOFG_00922 2.38e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LKMAKOFG_00923 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LKMAKOFG_00924 5.67e-177 yqeM - - Q - - - Methyltransferase
LKMAKOFG_00925 1.19e-192 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKMAKOFG_00926 1.63e-133 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LKMAKOFG_00927 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LKMAKOFG_00928 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LKMAKOFG_00929 1.82e-232 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LKMAKOFG_00930 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LKMAKOFG_00931 2.51e-260 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LKMAKOFG_00932 5.25e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LKMAKOFG_00933 1.04e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
LKMAKOFG_00934 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LKMAKOFG_00935 9.71e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LKMAKOFG_00936 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LKMAKOFG_00937 4.25e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LKMAKOFG_00938 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LKMAKOFG_00939 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LKMAKOFG_00940 1.09e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LKMAKOFG_00941 7.14e-181 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LKMAKOFG_00942 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LKMAKOFG_00943 8.3e-203 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LKMAKOFG_00944 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LKMAKOFG_00945 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LKMAKOFG_00946 3.83e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
LKMAKOFG_00947 4.78e-177 yqfA - - S - - - UPF0365 protein
LKMAKOFG_00948 4.34e-77 yqfB - - - - - - -
LKMAKOFG_00949 3.57e-61 yqfC - - S - - - sporulation protein YqfC
LKMAKOFG_00950 3.72e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LKMAKOFG_00951 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LKMAKOFG_00952 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LKMAKOFG_00953 1.44e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LKMAKOFG_00954 6.41e-84 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LKMAKOFG_00955 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LKMAKOFG_00956 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LKMAKOFG_00957 6e-24 - - - S - - - YqzL-like protein
LKMAKOFG_00958 2.5e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LKMAKOFG_00959 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LKMAKOFG_00960 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LKMAKOFG_00961 5.89e-145 ccpN - - K - - - CBS domain
LKMAKOFG_00962 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LKMAKOFG_00963 5.52e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
LKMAKOFG_00964 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LKMAKOFG_00965 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LKMAKOFG_00966 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LKMAKOFG_00967 8.52e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LKMAKOFG_00968 1.53e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LKMAKOFG_00969 1.18e-224 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LKMAKOFG_00970 4.82e-88 yqfQ - - S - - - YqfQ-like protein
LKMAKOFG_00971 1.89e-311 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LKMAKOFG_00972 9.96e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LKMAKOFG_00973 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
LKMAKOFG_00974 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKMAKOFG_00975 3.19e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LKMAKOFG_00976 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LKMAKOFG_00977 3.34e-80 yqfX - - S - - - membrane
LKMAKOFG_00978 1.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LKMAKOFG_00979 2.15e-63 yqfZ - - M ko:K06417 - ko00000 LysM domain
LKMAKOFG_00980 2.18e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
LKMAKOFG_00981 2.76e-99 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
LKMAKOFG_00982 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LKMAKOFG_00983 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LKMAKOFG_00984 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LKMAKOFG_00985 2.72e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LKMAKOFG_00986 1.15e-167 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LKMAKOFG_00987 1.68e-198 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LKMAKOFG_00988 2.39e-185 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKMAKOFG_00989 2.32e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LKMAKOFG_00990 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LKMAKOFG_00991 3.42e-68 yqzD - - - - - - -
LKMAKOFG_00992 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LKMAKOFG_00993 1.49e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LKMAKOFG_00994 5.38e-11 yqgO - - - - - - -
LKMAKOFG_00995 2.96e-275 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LKMAKOFG_00996 9.1e-39 yqgQ - - S - - - Protein conserved in bacteria
LKMAKOFG_00997 5.87e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LKMAKOFG_00998 1.98e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
LKMAKOFG_00999 5.17e-254 yqgU - - - - - - -
LKMAKOFG_01000 2.99e-65 dglA - - S - - - Thiamine-binding protein
LKMAKOFG_01001 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
LKMAKOFG_01002 9.9e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LKMAKOFG_01003 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
LKMAKOFG_01004 1.64e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
LKMAKOFG_01006 1.44e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKMAKOFG_01007 4.38e-303 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LKMAKOFG_01008 2.62e-238 yqxL - - P - - - Mg2 transporter protein
LKMAKOFG_01009 3.84e-258 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LKMAKOFG_01010 4.85e-235 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LKMAKOFG_01011 4.46e-66 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LKMAKOFG_01012 2.27e-93 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
LKMAKOFG_01013 1.56e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
LKMAKOFG_01014 5.28e-87 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LKMAKOFG_01015 2.33e-81 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LKMAKOFG_01016 8.16e-36 yqzE - - S - - - YqzE-like protein
LKMAKOFG_01017 6.88e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
LKMAKOFG_01018 1.1e-154 yqxM - - - ko:K19433 - ko00000 -
LKMAKOFG_01019 2.2e-101 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LKMAKOFG_01020 7.4e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LKMAKOFG_01021 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
LKMAKOFG_01022 9.44e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
LKMAKOFG_01023 8.78e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
LKMAKOFG_01024 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKMAKOFG_01025 4.04e-265 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LKMAKOFG_01026 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKMAKOFG_01027 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LKMAKOFG_01028 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LKMAKOFG_01029 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LKMAKOFG_01030 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LKMAKOFG_01031 2.01e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LKMAKOFG_01032 7.65e-83 yqhP - - - - - - -
LKMAKOFG_01033 1.04e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
LKMAKOFG_01034 3.28e-117 yqhR - - S - - - Conserved membrane protein YqhR
LKMAKOFG_01035 7.36e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LKMAKOFG_01036 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LKMAKOFG_01037 2.33e-48 yqhV - - S - - - Protein of unknown function (DUF2619)
LKMAKOFG_01038 1.27e-220 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LKMAKOFG_01039 6.93e-112 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LKMAKOFG_01040 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LKMAKOFG_01041 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LKMAKOFG_01042 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LKMAKOFG_01043 4.32e-44 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LKMAKOFG_01044 1.74e-66 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LKMAKOFG_01045 3.99e-130 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LKMAKOFG_01046 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LKMAKOFG_01047 4.67e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LKMAKOFG_01048 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LKMAKOFG_01049 1.36e-87 yqhY - - S - - - protein conserved in bacteria
LKMAKOFG_01050 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LKMAKOFG_01051 1.45e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LKMAKOFG_01052 5.83e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKMAKOFG_01053 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LKMAKOFG_01054 9.49e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LKMAKOFG_01055 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LKMAKOFG_01056 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LKMAKOFG_01057 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LKMAKOFG_01058 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LKMAKOFG_01059 8.85e-304 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LKMAKOFG_01060 6.11e-187 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LKMAKOFG_01061 2.48e-275 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKMAKOFG_01064 9.67e-274 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LKMAKOFG_01066 1.15e-145 - - - K - - - Protein of unknown function (DUF1232)
LKMAKOFG_01067 1.13e-130 - - - P - - - Probably functions as a manganese efflux pump
LKMAKOFG_01069 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
LKMAKOFG_01070 1.1e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LKMAKOFG_01071 7.62e-270 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LKMAKOFG_01072 5.06e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LKMAKOFG_01073 7.51e-262 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LKMAKOFG_01074 4.18e-262 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LKMAKOFG_01075 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LKMAKOFG_01076 4.67e-204 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LKMAKOFG_01077 6.25e-47 yqzF - - S - - - Protein of unknown function (DUF2627)
LKMAKOFG_01078 0.0 bkdR - - KT - - - Transcriptional regulator
LKMAKOFG_01079 1.67e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
LKMAKOFG_01080 2.61e-260 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LKMAKOFG_01081 1.2e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
LKMAKOFG_01082 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKMAKOFG_01083 4.56e-221 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKMAKOFG_01084 9.83e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKMAKOFG_01085 7.25e-284 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKMAKOFG_01086 4.26e-219 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKMAKOFG_01087 6.87e-99 yqiW - - S - - - Belongs to the UPF0403 family
LKMAKOFG_01088 5.59e-173 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LKMAKOFG_01089 4.25e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LKMAKOFG_01090 4.99e-164 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKMAKOFG_01091 4.58e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LKMAKOFG_01092 3.7e-123 yqjB - - S - - - protein conserved in bacteria
LKMAKOFG_01094 5.42e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
LKMAKOFG_01095 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKMAKOFG_01096 4.32e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LKMAKOFG_01097 5.86e-191 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKMAKOFG_01098 1.36e-36 yqzJ - - - - - - -
LKMAKOFG_01099 1.92e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKMAKOFG_01100 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LKMAKOFG_01101 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LKMAKOFG_01102 1.67e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LKMAKOFG_01103 3.71e-188 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LKMAKOFG_01104 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LKMAKOFG_01105 1.11e-66 - - - S - - - GlpM protein
LKMAKOFG_01106 1.86e-210 - - - K - - - LysR substrate binding domain
LKMAKOFG_01107 4.32e-122 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LKMAKOFG_01108 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKMAKOFG_01111 2.25e-313 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKMAKOFG_01112 2.78e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LKMAKOFG_01113 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_01114 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_01115 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_01116 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_01117 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_01118 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_01119 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKMAKOFG_01120 1.15e-280 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKMAKOFG_01121 6.46e-305 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LKMAKOFG_01122 3.97e-174 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
LKMAKOFG_01123 1.17e-186 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKMAKOFG_01124 6.83e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKMAKOFG_01125 3.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_01126 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LKMAKOFG_01127 6.33e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LKMAKOFG_01128 4.44e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKMAKOFG_01130 1.68e-237 yueF - - S - - - transporter activity
LKMAKOFG_01132 3.08e-74 - - - S - - - YolD-like protein
LKMAKOFG_01133 5.45e-298 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LKMAKOFG_01134 1.15e-114 yqjY - - K ko:K06977 - ko00000 acetyltransferase
LKMAKOFG_01135 5.96e-81 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
LKMAKOFG_01136 4.5e-227 yqkA - - K - - - GrpB protein
LKMAKOFG_01137 4.44e-79 yqkB - - S - - - Belongs to the HesB IscA family
LKMAKOFG_01138 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
LKMAKOFG_01139 2e-221 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LKMAKOFG_01140 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
LKMAKOFG_01141 8.88e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LKMAKOFG_01142 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
LKMAKOFG_01143 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LKMAKOFG_01144 8.39e-280 yqxK - - L - - - DNA helicase
LKMAKOFG_01145 1.34e-74 ansR - - K - - - Transcriptional regulator
LKMAKOFG_01146 1.3e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LKMAKOFG_01147 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
LKMAKOFG_01148 5.89e-312 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LKMAKOFG_01149 4.12e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LKMAKOFG_01150 1.96e-30 - - - - - - - -
LKMAKOFG_01151 4.38e-47 yqkK - - - - - - -
LKMAKOFG_01153 3.53e-142 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LKMAKOFG_01154 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LKMAKOFG_01155 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
LKMAKOFG_01156 1.53e-211 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LKMAKOFG_01157 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LKMAKOFG_01158 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LKMAKOFG_01159 1.43e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKMAKOFG_01160 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LKMAKOFG_01161 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LKMAKOFG_01162 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKMAKOFG_01163 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LKMAKOFG_01164 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LKMAKOFG_01165 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LKMAKOFG_01166 3.34e-243 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LKMAKOFG_01167 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
LKMAKOFG_01168 1.85e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
LKMAKOFG_01169 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LKMAKOFG_01170 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LKMAKOFG_01171 6.31e-199 ypuA - - S - - - Secreted protein
LKMAKOFG_01172 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LKMAKOFG_01173 9.6e-106 ccdC1 - - O - - - Protein of unknown function (DUF1453)
LKMAKOFG_01174 1.09e-129 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LKMAKOFG_01175 4.92e-71 ypuD - - - - - - -
LKMAKOFG_01176 1.31e-268 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LKMAKOFG_01177 3.97e-144 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LKMAKOFG_01178 7.34e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LKMAKOFG_01179 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LKMAKOFG_01180 1.58e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKMAKOFG_01181 5.71e-121 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
LKMAKOFG_01183 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LKMAKOFG_01184 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LKMAKOFG_01185 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
LKMAKOFG_01186 3.26e-275 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKMAKOFG_01187 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LKMAKOFG_01188 8.99e-116 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LKMAKOFG_01189 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LKMAKOFG_01190 3.04e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LKMAKOFG_01191 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LKMAKOFG_01192 1.53e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LKMAKOFG_01193 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_01194 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_01195 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKMAKOFG_01196 5.62e-254 rsiX - - - - - - -
LKMAKOFG_01197 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKMAKOFG_01198 2.16e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LKMAKOFG_01199 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
LKMAKOFG_01200 2.03e-251 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LKMAKOFG_01201 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKMAKOFG_01202 8.98e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LKMAKOFG_01203 8.33e-132 ypbE - - M - - - Lysin motif
LKMAKOFG_01204 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
LKMAKOFG_01205 1.15e-189 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LKMAKOFG_01206 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKMAKOFG_01207 7.37e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LKMAKOFG_01208 1.85e-239 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LKMAKOFG_01209 1.84e-155 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LKMAKOFG_01210 1.92e-204 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LKMAKOFG_01211 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LKMAKOFG_01212 1.43e-78 ypfA - - M - - - Flagellar protein YcgR
LKMAKOFG_01213 1.93e-18 - - - S - - - Family of unknown function (DUF5359)
LKMAKOFG_01214 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LKMAKOFG_01215 5.73e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LKMAKOFG_01216 4.86e-237 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LKMAKOFG_01217 1.87e-12 - - - S - - - YpzI-like protein
LKMAKOFG_01218 6.19e-136 yphA - - - - - - -
LKMAKOFG_01219 1.91e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LKMAKOFG_01220 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LKMAKOFG_01221 6.23e-22 yphE - - S - - - Protein of unknown function (DUF2768)
LKMAKOFG_01222 3.4e-173 yphF - - - - - - -
LKMAKOFG_01223 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LKMAKOFG_01224 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LKMAKOFG_01225 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LKMAKOFG_01226 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LKMAKOFG_01227 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LKMAKOFG_01228 4.49e-168 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LKMAKOFG_01229 3.79e-250 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LKMAKOFG_01230 8.53e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LKMAKOFG_01231 6.12e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LKMAKOFG_01232 1.14e-274 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LKMAKOFG_01233 2.23e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LKMAKOFG_01234 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LKMAKOFG_01235 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKMAKOFG_01236 3.92e-210 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LKMAKOFG_01237 2.46e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LKMAKOFG_01238 2.49e-148 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LKMAKOFG_01239 3.74e-285 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LKMAKOFG_01240 1.33e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LKMAKOFG_01241 1.76e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LKMAKOFG_01242 1.52e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LKMAKOFG_01243 3.31e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LKMAKOFG_01244 2.5e-297 ypiA - - S - - - COG0457 FOG TPR repeat
LKMAKOFG_01245 2.6e-129 ypiB - - S - - - Belongs to the UPF0302 family
LKMAKOFG_01246 2.75e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
LKMAKOFG_01247 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LKMAKOFG_01248 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LKMAKOFG_01249 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LKMAKOFG_01250 7.24e-134 ypjA - - S - - - membrane
LKMAKOFG_01251 2.05e-182 ypjB - - S - - - sporulation protein
LKMAKOFG_01252 3.9e-287 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LKMAKOFG_01253 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKMAKOFG_01254 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LKMAKOFG_01255 1.62e-187 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LKMAKOFG_01256 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
LKMAKOFG_01257 4.48e-170 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
LKMAKOFG_01258 1.21e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LKMAKOFG_01259 6.9e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LKMAKOFG_01260 7.73e-231 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LKMAKOFG_01261 5.43e-191 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LKMAKOFG_01262 3.44e-203 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LKMAKOFG_01263 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LKMAKOFG_01264 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LKMAKOFG_01265 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
LKMAKOFG_01266 1.87e-102 ypmB - - S - - - protein conserved in bacteria
LKMAKOFG_01267 1.46e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LKMAKOFG_01268 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LKMAKOFG_01269 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LKMAKOFG_01270 1.02e-157 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LKMAKOFG_01271 3e-118 ypoC - - - - - - -
LKMAKOFG_01272 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LKMAKOFG_01273 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKMAKOFG_01274 1.11e-236 yppC - - S - - - Protein of unknown function (DUF2515)
LKMAKOFG_01275 0.000542 - - - - ko:K06430 - ko00000 -
LKMAKOFG_01279 1.93e-76 yppG - - S - - - YppG-like protein
LKMAKOFG_01280 5.29e-95 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LKMAKOFG_01281 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LKMAKOFG_01282 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LKMAKOFG_01283 9.47e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LKMAKOFG_01285 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
LKMAKOFG_01286 1.89e-128 ypsA - - S - - - Belongs to the UPF0398 family
LKMAKOFG_01287 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LKMAKOFG_01288 5.34e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LKMAKOFG_01289 6.91e-31 - - - S - - - YpzG-like protein
LKMAKOFG_01291 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
LKMAKOFG_01292 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LKMAKOFG_01293 2e-129 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LKMAKOFG_01294 8.39e-297 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
LKMAKOFG_01295 2.63e-06 - - - - - - - -
LKMAKOFG_01296 1.27e-129 yrdC - - Q - - - Isochorismatase family
LKMAKOFG_01297 3.19e-126 ydfR - - S - - - Protein of unknown function (DUF421)
LKMAKOFG_01298 1.53e-12 - - - S - - - Bacillus cereus group antimicrobial protein
LKMAKOFG_01299 3.81e-67 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
LKMAKOFG_01300 3.57e-136 - - - J - - - Acetyltransferase (GNAT) domain
LKMAKOFG_01301 5.99e-267 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LKMAKOFG_01302 7.28e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
LKMAKOFG_01303 0.0 ypbR - - S - - - Dynamin family
LKMAKOFG_01304 5.79e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
LKMAKOFG_01305 2.44e-10 - - - - - - - -
LKMAKOFG_01306 3.33e-210 ypcP - - L - - - 5'3' exonuclease
LKMAKOFG_01308 2.47e-88 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
LKMAKOFG_01309 2.79e-154 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LKMAKOFG_01310 2.06e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
LKMAKOFG_01311 6.59e-40 ypeQ - - S - - - Zinc-finger
LKMAKOFG_01312 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
LKMAKOFG_01313 5.19e-17 degR - - - - - - -
LKMAKOFG_01314 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LKMAKOFG_01315 1.49e-274 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LKMAKOFG_01316 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LKMAKOFG_01317 3.93e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LKMAKOFG_01318 2.29e-128 yagB - - S ko:K06950 - ko00000 phosphohydrolase
LKMAKOFG_01319 2.21e-201 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LKMAKOFG_01320 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LKMAKOFG_01321 6.82e-99 yphP - - S - - - Belongs to the UPF0403 family
LKMAKOFG_01322 1.73e-172 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
LKMAKOFG_01323 3.08e-146 ypjP - - S - - - YpjP-like protein
LKMAKOFG_01324 6.22e-204 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LKMAKOFG_01325 3.01e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LKMAKOFG_01326 6.97e-150 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKMAKOFG_01327 1.5e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LKMAKOFG_01328 2.88e-224 yplP - - K - - - Transcriptional regulator
LKMAKOFG_01329 1.73e-308 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LKMAKOFG_01330 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
LKMAKOFG_01331 9.14e-146 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LKMAKOFG_01332 8.65e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
LKMAKOFG_01333 5.59e-126 ypmS - - S - - - protein conserved in bacteria
LKMAKOFG_01334 3.35e-89 ypoP - - K - - - transcriptional
LKMAKOFG_01335 1.99e-132 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LKMAKOFG_01336 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LKMAKOFG_01337 3.43e-134 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LKMAKOFG_01338 0.0 yokA - - L - - - Recombinase
LKMAKOFG_01339 1.5e-109 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LKMAKOFG_01340 2.62e-102 - - - G - - - SMI1-KNR4 cell-wall
LKMAKOFG_01341 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
LKMAKOFG_01342 3.35e-116 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
LKMAKOFG_01343 6.78e-108 yokK - - S - - - SMI1 / KNR4 family
LKMAKOFG_01344 2.01e-15 - - - S - - - Acetyltransferase (GNAT) domain
LKMAKOFG_01346 5.14e-22 - - - S - - - Protein of unknown function (DUF2651)
LKMAKOFG_01347 4.93e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
LKMAKOFG_01348 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
LKMAKOFG_01349 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
LKMAKOFG_01350 6.74e-266 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
LKMAKOFG_01352 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
LKMAKOFG_01353 6.03e-46 - - - - - - - -
LKMAKOFG_01354 2.81e-106 - - - K - - - Helix-turn-helix XRE-family like proteins
LKMAKOFG_01355 3.84e-258 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LKMAKOFG_01356 7.96e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LKMAKOFG_01357 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LKMAKOFG_01358 4.26e-113 ybfM - - S - - - SNARE associated Golgi protein
LKMAKOFG_01359 7.49e-195 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LKMAKOFG_01360 8.67e-55 ybfN - - - - - - -
LKMAKOFG_01361 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LKMAKOFG_01362 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKMAKOFG_01363 5.02e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LKMAKOFG_01364 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKMAKOFG_01365 1.97e-228 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
LKMAKOFG_01366 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LKMAKOFG_01367 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LKMAKOFG_01368 1.26e-278 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_01369 5.81e-221 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
LKMAKOFG_01370 7.92e-07 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
LKMAKOFG_01371 4.85e-35 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
LKMAKOFG_01372 1.05e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKMAKOFG_01373 1.64e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
LKMAKOFG_01374 3.42e-232 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LKMAKOFG_01375 2.3e-83 ydfP - - S ko:K15977 - ko00000 DoxX
LKMAKOFG_01376 9.27e-75 ydfQ - - CO - - - Thioredoxin
LKMAKOFG_01377 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
LKMAKOFG_01378 4.29e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LKMAKOFG_01379 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
LKMAKOFG_01380 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKMAKOFG_01381 8.56e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKMAKOFG_01382 1.99e-153 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LKMAKOFG_01383 1.58e-262 ycbU - - E - - - Selenocysteine lyase
LKMAKOFG_01384 5.04e-313 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LKMAKOFG_01385 2.56e-129 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LKMAKOFG_01386 8.92e-251 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LKMAKOFG_01387 9.42e-147 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LKMAKOFG_01388 1.13e-250 yccF - - K ko:K07039 - ko00000 SEC-C motif
LKMAKOFG_01389 4.41e-218 yccK - - C - - - Aldo keto reductase
LKMAKOFG_01390 2.66e-225 ycdA - - S - - - Domain of unknown function (DUF5105)
LKMAKOFG_01391 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKMAKOFG_01392 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKMAKOFG_01393 7.3e-121 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LKMAKOFG_01394 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LKMAKOFG_01395 1.74e-178 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LKMAKOFG_01396 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LKMAKOFG_01397 6.03e-213 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LKMAKOFG_01398 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LKMAKOFG_01399 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LKMAKOFG_01400 6.94e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKMAKOFG_01401 3.34e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
LKMAKOFG_01402 7.32e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LKMAKOFG_01403 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LKMAKOFG_01404 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
LKMAKOFG_01405 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
LKMAKOFG_01406 3.34e-246 yceH - - P - - - Belongs to the TelA family
LKMAKOFG_01407 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LKMAKOFG_01408 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LKMAKOFG_01409 9.97e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LKMAKOFG_01410 2.85e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LKMAKOFG_01411 1.47e-266 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
LKMAKOFG_01412 4.64e-293 ycgA - - S - - - Membrane
LKMAKOFG_01413 1.27e-105 ycgB - - - - - - -
LKMAKOFG_01414 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LKMAKOFG_01415 1.14e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LKMAKOFG_01416 0.0 mdr - - EGP - - - the major facilitator superfamily
LKMAKOFG_01417 2.82e-100 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_01418 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
LKMAKOFG_01419 3.44e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LKMAKOFG_01420 6.64e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKMAKOFG_01421 3.22e-146 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
LKMAKOFG_01422 3.54e-189 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LKMAKOFG_01423 5.77e-08 - - - S - - - Bacillus cereus group antimicrobial protein
LKMAKOFG_01424 3.2e-171 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
LKMAKOFG_01425 7.05e-290 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_01426 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LKMAKOFG_01427 2.41e-235 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
LKMAKOFG_01428 3.64e-182 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
LKMAKOFG_01429 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LKMAKOFG_01430 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKMAKOFG_01431 6.34e-311 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKMAKOFG_01432 1.43e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
LKMAKOFG_01433 1.93e-241 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LKMAKOFG_01434 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LKMAKOFG_01435 4.03e-73 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
LKMAKOFG_01436 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LKMAKOFG_01437 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKMAKOFG_01438 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
LKMAKOFG_01439 2.01e-285 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LKMAKOFG_01440 4.25e-291 yciC - - S - - - GTPases (G3E family)
LKMAKOFG_01441 1.02e-280 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LKMAKOFG_01442 2.2e-95 yckC - - S - - - membrane
LKMAKOFG_01443 9.5e-68 - - - S - - - Protein of unknown function (DUF2680)
LKMAKOFG_01444 5.81e-92 nin - - S - - - Competence protein J (ComJ)
LKMAKOFG_01445 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
LKMAKOFG_01446 5.17e-123 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LKMAKOFG_01447 5.21e-138 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
LKMAKOFG_01448 4.1e-84 hxlR - - K - - - transcriptional
LKMAKOFG_01449 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_01450 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_01451 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
LKMAKOFG_01452 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
LKMAKOFG_01453 1.91e-316 - - - E - - - Aminotransferase class I and II
LKMAKOFG_01454 1.3e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LKMAKOFG_01455 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
LKMAKOFG_01456 3.24e-168 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKMAKOFG_01457 2.03e-153 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LKMAKOFG_01458 2.8e-187 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LKMAKOFG_01459 1.71e-205 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
LKMAKOFG_01460 1.4e-129 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LKMAKOFG_01461 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LKMAKOFG_01462 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
LKMAKOFG_01463 3.37e-100 yclD - - - - - - -
LKMAKOFG_01464 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LKMAKOFG_01465 0.0 yclG - - M - - - Pectate lyase superfamily protein
LKMAKOFG_01467 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
LKMAKOFG_01468 8.42e-302 gerKC - - S ko:K06297 - ko00000 spore germination
LKMAKOFG_01469 1.86e-248 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
LKMAKOFG_01470 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKMAKOFG_01471 4.43e-120 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKMAKOFG_01472 6.34e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LKMAKOFG_01473 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LKMAKOFG_01474 9.29e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_01475 1.33e-274 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LKMAKOFG_01476 0.0 yxeQ - - S - - - MmgE/PrpD family
LKMAKOFG_01477 8.03e-159 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LKMAKOFG_01478 1.61e-309 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
LKMAKOFG_01479 7.47e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_01480 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
LKMAKOFG_01481 5.98e-100 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LKMAKOFG_01484 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LKMAKOFG_01485 3.85e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_01486 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_01487 1.61e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_01488 3.95e-223 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LKMAKOFG_01489 1.39e-313 ycnB - - EGP - - - the major facilitator superfamily
LKMAKOFG_01490 7.4e-196 ycnC - - K - - - Transcriptional regulator
LKMAKOFG_01491 2.79e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
LKMAKOFG_01492 8.02e-59 ycnE - - S - - - Monooxygenase
LKMAKOFG_01493 7.91e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LKMAKOFG_01494 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKMAKOFG_01495 7.59e-288 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKMAKOFG_01496 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKMAKOFG_01497 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
LKMAKOFG_01498 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_01499 2.05e-131 ycnI - - S - - - protein conserved in bacteria
LKMAKOFG_01500 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LKMAKOFG_01501 4.98e-137 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LKMAKOFG_01502 9.6e-73 - - - - - - - -
LKMAKOFG_01503 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LKMAKOFG_01504 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LKMAKOFG_01505 4.92e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
LKMAKOFG_01506 6.81e-86 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LKMAKOFG_01508 2.69e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LKMAKOFG_01509 2.49e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LKMAKOFG_01510 2.66e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
LKMAKOFG_01511 4.87e-192 ycsI - - S - - - Belongs to the D-glutamate cyclase family
LKMAKOFG_01512 9.41e-175 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LKMAKOFG_01513 2.96e-241 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LKMAKOFG_01514 1.14e-167 kipR - - K - - - Transcriptional regulator
LKMAKOFG_01515 2.23e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
LKMAKOFG_01517 1.2e-74 yczJ - - S - - - biosynthesis
LKMAKOFG_01518 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LKMAKOFG_01519 1.05e-220 ycsN - - S - - - Oxidoreductase
LKMAKOFG_01520 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
LKMAKOFG_01521 0.0 ydaB - - IQ - - - acyl-CoA ligase
LKMAKOFG_01522 9.37e-208 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_01523 5.56e-125 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
LKMAKOFG_01524 2.34e-148 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LKMAKOFG_01525 1.83e-101 ydaG - - S - - - general stress protein
LKMAKOFG_01526 2.54e-176 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LKMAKOFG_01527 6.54e-63 ydzA - - EGP - - - Domain of unknown function (DUF3817)
LKMAKOFG_01528 3.25e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LKMAKOFG_01529 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LKMAKOFG_01530 4e-258 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LKMAKOFG_01531 1.54e-188 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
LKMAKOFG_01532 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
LKMAKOFG_01533 7.53e-302 ydaM - - M - - - Glycosyl transferase family group 2
LKMAKOFG_01534 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
LKMAKOFG_01536 0.0 ydaO - - E - - - amino acid
LKMAKOFG_01537 4.9e-50 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LKMAKOFG_01538 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
LKMAKOFG_01539 6.65e-85 - - - K - - - acetyltransferase
LKMAKOFG_01540 9.42e-13 - - - - - - - -
LKMAKOFG_01542 1.99e-111 - - - - - - - -
LKMAKOFG_01543 2.34e-127 - - - - - - - -
LKMAKOFG_01544 1.29e-54 - - - - - - - -
LKMAKOFG_01545 1.87e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LKMAKOFG_01547 1.95e-45 ydaT - - - - - - -
LKMAKOFG_01548 5.32e-94 yvaD - - S - - - Family of unknown function (DUF5360)
LKMAKOFG_01549 2.87e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LKMAKOFG_01550 6.29e-181 ydbA - - P - - - EcsC protein family
LKMAKOFG_01551 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
LKMAKOFG_01552 2.65e-78 ydbB - - G - - - Cupin domain
LKMAKOFG_01553 5.49e-198 ydbD - - P ko:K07217 - ko00000 Catalase
LKMAKOFG_01554 1.49e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LKMAKOFG_01555 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LKMAKOFG_01556 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LKMAKOFG_01557 1.59e-286 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKMAKOFG_01558 7.07e-230 ydbI - - S - - - AI-2E family transporter
LKMAKOFG_01559 1.67e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_01560 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKMAKOFG_01561 5.4e-69 ydbL - - - - - - -
LKMAKOFG_01562 5.07e-260 ydbM - - I - - - acyl-CoA dehydrogenase
LKMAKOFG_01563 1.13e-15 - - - S - - - Fur-regulated basic protein B
LKMAKOFG_01564 9.35e-14 - - - S - - - Fur-regulated basic protein A
LKMAKOFG_01565 3.47e-161 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKMAKOFG_01566 4.55e-74 ydbP - - CO - - - Thioredoxin
LKMAKOFG_01567 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LKMAKOFG_01568 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LKMAKOFG_01569 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LKMAKOFG_01570 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LKMAKOFG_01571 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
LKMAKOFG_01572 2.08e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
LKMAKOFG_01573 1.09e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LKMAKOFG_01574 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LKMAKOFG_01575 2.41e-280 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LKMAKOFG_01576 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LKMAKOFG_01577 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LKMAKOFG_01578 1.05e-186 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LKMAKOFG_01579 6.28e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LKMAKOFG_01580 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LKMAKOFG_01581 1.03e-240 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LKMAKOFG_01582 9.77e-71 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LKMAKOFG_01583 1.68e-109 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LKMAKOFG_01584 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LKMAKOFG_01585 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LKMAKOFG_01586 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LKMAKOFG_01587 1.78e-21 - - - - - - - -
LKMAKOFG_01588 4.99e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
LKMAKOFG_01596 2.9e-131 ydcL - - L - - - Belongs to the 'phage' integrase family
LKMAKOFG_01599 3.27e-135 yfcA - - S ko:K07090 - ko00000 membrane transporter protein
LKMAKOFG_01600 1.11e-104 yhfK_2 - - GM - - - Nucleoside-diphosphate-sugar epimerases
LKMAKOFG_01601 8.36e-48 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_01602 8.56e-211 yqjM1 - - C - - - NADPH dehydrogenase
LKMAKOFG_01603 1.56e-46 - - - S - - - Putative lumazine-binding
LKMAKOFG_01604 3.81e-128 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_01606 9.76e-192 - - - S - - - Serine aminopeptidase, S33
LKMAKOFG_01607 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
LKMAKOFG_01608 5.16e-66 ohrR - - K - - - Transcriptional regulator
LKMAKOFG_01609 4.49e-81 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
LKMAKOFG_01610 4.3e-96 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
LKMAKOFG_01611 6.98e-84 - - - S - - - YjbR
LKMAKOFG_01612 4.07e-97 ywnA - - K - - - Transcriptional regulator
LKMAKOFG_01613 2.22e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LKMAKOFG_01615 7.18e-117 - - - K ko:K16137 - ko00000,ko03000 Bacterial regulatory proteins, tetR family
LKMAKOFG_01616 2.24e-144 - - - C ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
LKMAKOFG_01617 1.16e-222 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKMAKOFG_01618 1.04e-248 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LKMAKOFG_01619 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LKMAKOFG_01620 4.87e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
LKMAKOFG_01621 1.75e-157 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LKMAKOFG_01622 4.26e-133 - - - S - - - Protein of unknown function (DUF2812)
LKMAKOFG_01623 2.86e-68 - - - K - - - Transcriptional regulator PadR-like family
LKMAKOFG_01624 1.54e-218 ybfA - - K - - - FR47-like protein
LKMAKOFG_01625 3.55e-296 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_01626 2.51e-234 - - - S - - - Patatin-like phospholipase
LKMAKOFG_01627 3.4e-108 - - - S - - - DinB superfamily
LKMAKOFG_01628 1.43e-82 - - - G - - - Cupin domain
LKMAKOFG_01631 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
LKMAKOFG_01632 1.86e-216 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LKMAKOFG_01633 1.05e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
LKMAKOFG_01635 1.91e-130 yrkC - - G - - - Cupin domain
LKMAKOFG_01636 2.3e-66 ydeH - - - - - - -
LKMAKOFG_01637 3.57e-213 - - - S - - - Sodium Bile acid symporter family
LKMAKOFG_01638 6.37e-258 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
LKMAKOFG_01639 2.09e-86 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LKMAKOFG_01640 5.56e-288 nhaC_1 - - C - - - antiporter
LKMAKOFG_01641 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
LKMAKOFG_01642 1.46e-146 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_01644 2.16e-250 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
LKMAKOFG_01645 9.88e-132 ydeS - - K - - - Transcriptional regulator
LKMAKOFG_01646 5.04e-200 ydeK - - EG - - - -transporter
LKMAKOFG_01647 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKMAKOFG_01648 5.09e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
LKMAKOFG_01649 1.19e-33 yraE - - - ko:K06440 - ko00000 -
LKMAKOFG_01650 3.04e-282 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LKMAKOFG_01651 4.76e-84 yraF - - M - - - Spore coat protein
LKMAKOFG_01652 4.19e-50 yraG - - - ko:K06440 - ko00000 -
LKMAKOFG_01653 1.16e-273 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_01654 1.39e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_01655 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
LKMAKOFG_01656 2.4e-171 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
LKMAKOFG_01657 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LKMAKOFG_01658 1.29e-127 ynaD - - J - - - Acetyltransferase (GNAT) domain
LKMAKOFG_01659 1.74e-191 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKMAKOFG_01660 1.08e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
LKMAKOFG_01661 3.9e-268 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LKMAKOFG_01662 1.37e-288 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKMAKOFG_01663 3.05e-198 - - - K - - - Helix-turn-helix XRE-family like proteins
LKMAKOFG_01664 3.66e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LKMAKOFG_01665 4.35e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
LKMAKOFG_01666 2.81e-191 bltR - - K - - - helix_turn_helix, mercury resistance
LKMAKOFG_01667 7.33e-191 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LKMAKOFG_01668 3.88e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LKMAKOFG_01669 6.64e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
LKMAKOFG_01670 1.77e-211 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Isocitrate/isopropylmalate dehydrogenase
LKMAKOFG_01671 2.29e-154 ydhC - - K - - - FCD
LKMAKOFG_01672 4.77e-291 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKMAKOFG_01675 0.0 pbpE - - V - - - Beta-lactamase
LKMAKOFG_01677 4.3e-128 ydhK - - M - - - Protein of unknown function (DUF1541)
LKMAKOFG_01678 3.18e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
LKMAKOFG_01679 3.41e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
LKMAKOFG_01680 1.88e-153 - - - K ko:K05799 - ko00000,ko03000 FCD
LKMAKOFG_01681 7.13e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LKMAKOFG_01682 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
LKMAKOFG_01683 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LKMAKOFG_01684 2.98e-135 yvdT_1 - - K - - - Transcriptional regulator
LKMAKOFG_01685 0.0 ybeC - - E - - - amino acid
LKMAKOFG_01686 1.26e-213 ydhU - - P ko:K07217 - ko00000 Catalase
LKMAKOFG_01687 2.93e-112 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
LKMAKOFG_01688 2.83e-237 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LKMAKOFG_01689 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKMAKOFG_01693 1.95e-189 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
LKMAKOFG_01695 9.1e-127 yqaC - - F - - - adenylate kinase activity
LKMAKOFG_01696 4.56e-34 - - - K - - - acetyltransferase
LKMAKOFG_01697 1.53e-279 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_01698 8.64e-105 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
LKMAKOFG_01699 4.76e-121 - - - S - - - DinB family
LKMAKOFG_01700 4.15e-190 supH - - S - - - hydrolase
LKMAKOFG_01701 6.84e-186 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
LKMAKOFG_01702 2.04e-168 - - - K - - - Helix-turn-helix domain, rpiR family
LKMAKOFG_01703 4.89e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LKMAKOFG_01704 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_01705 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
LKMAKOFG_01706 3.42e-233 romA - - S - - - Beta-lactamase superfamily domain
LKMAKOFG_01707 4.62e-107 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LKMAKOFG_01708 2.17e-210 yybE - - K - - - Transcriptional regulator
LKMAKOFG_01709 2.28e-271 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_01710 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LKMAKOFG_01711 4.77e-130 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LKMAKOFG_01712 9.01e-121 yrhH - - Q - - - methyltransferase
LKMAKOFG_01713 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
LKMAKOFG_01714 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LKMAKOFG_01715 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
LKMAKOFG_01716 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LKMAKOFG_01717 3.91e-105 yrhD - - S - - - Protein of unknown function (DUF1641)
LKMAKOFG_01718 2.73e-46 yrhC - - S - - - YrhC-like protein
LKMAKOFG_01719 7.93e-270 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LKMAKOFG_01720 1.87e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LKMAKOFG_01721 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LKMAKOFG_01722 1.35e-150 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LKMAKOFG_01723 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
LKMAKOFG_01724 2.92e-123 yrrS - - S - - - Protein of unknown function (DUF1510)
LKMAKOFG_01725 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
LKMAKOFG_01726 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LKMAKOFG_01727 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LKMAKOFG_01728 1.88e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LKMAKOFG_01729 3.64e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LKMAKOFG_01730 2.32e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LKMAKOFG_01731 1.9e-257 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LKMAKOFG_01732 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
LKMAKOFG_01733 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LKMAKOFG_01734 1.1e-55 yrzL - - S - - - Belongs to the UPF0297 family
LKMAKOFG_01735 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LKMAKOFG_01736 5.69e-238 yrrI - - S - - - AI-2E family transporter
LKMAKOFG_01737 3.81e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LKMAKOFG_01738 1.05e-187 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LKMAKOFG_01739 5.6e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKMAKOFG_01740 4.4e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LKMAKOFG_01741 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
LKMAKOFG_01742 8.4e-42 yrzR - - - - - - -
LKMAKOFG_01743 2.92e-106 yrrD - - S - - - protein conserved in bacteria
LKMAKOFG_01744 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LKMAKOFG_01745 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
LKMAKOFG_01746 3.55e-282 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LKMAKOFG_01747 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LKMAKOFG_01748 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_01749 5.09e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LKMAKOFG_01750 1.18e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LKMAKOFG_01751 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LKMAKOFG_01752 3.5e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LKMAKOFG_01755 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LKMAKOFG_01756 2.86e-97 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LKMAKOFG_01757 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LKMAKOFG_01758 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LKMAKOFG_01759 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LKMAKOFG_01760 2.23e-62 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
LKMAKOFG_01761 1.79e-111 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LKMAKOFG_01762 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LKMAKOFG_01763 3.33e-66 yrzD - - S - - - Post-transcriptional regulator
LKMAKOFG_01764 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKMAKOFG_01765 2.98e-140 yrbG - - S - - - membrane
LKMAKOFG_01766 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
LKMAKOFG_01767 2.09e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LKMAKOFG_01768 8.2e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LKMAKOFG_01769 5.79e-246 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LKMAKOFG_01770 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
LKMAKOFG_01771 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LKMAKOFG_01772 2.33e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LKMAKOFG_01773 2.96e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
LKMAKOFG_01775 3.13e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKMAKOFG_01776 8.44e-254 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LKMAKOFG_01777 3.91e-268 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LKMAKOFG_01778 3.69e-196 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LKMAKOFG_01779 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LKMAKOFG_01780 5.72e-285 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LKMAKOFG_01781 9.72e-121 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LKMAKOFG_01782 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
LKMAKOFG_01783 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LKMAKOFG_01784 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LKMAKOFG_01785 2.87e-137 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LKMAKOFG_01786 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LKMAKOFG_01787 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LKMAKOFG_01788 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LKMAKOFG_01789 1.71e-204 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LKMAKOFG_01790 3.98e-188 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LKMAKOFG_01791 3.94e-184 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LKMAKOFG_01792 8e-154 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LKMAKOFG_01793 6.14e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LKMAKOFG_01794 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LKMAKOFG_01795 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LKMAKOFG_01796 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LKMAKOFG_01797 1e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
LKMAKOFG_01798 4.92e-206 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
LKMAKOFG_01799 6.05e-170 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LKMAKOFG_01800 9.28e-308 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LKMAKOFG_01801 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LKMAKOFG_01802 4.38e-35 - - - - - - - -
LKMAKOFG_01803 1.81e-249 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LKMAKOFG_01804 3.63e-304 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LKMAKOFG_01805 2.68e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LKMAKOFG_01806 3.43e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LKMAKOFG_01807 1.1e-181 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LKMAKOFG_01808 4.26e-222 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LKMAKOFG_01809 1.88e-186 hemX - - O ko:K02497 - ko00000 cytochrome C
LKMAKOFG_01810 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LKMAKOFG_01811 4.78e-115 ysxD - - - - - - -
LKMAKOFG_01812 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LKMAKOFG_01813 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LKMAKOFG_01814 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LKMAKOFG_01815 1.34e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LKMAKOFG_01816 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LKMAKOFG_01817 1.35e-240 ysoA - - H - - - Tetratricopeptide repeat
LKMAKOFG_01818 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKMAKOFG_01819 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LKMAKOFG_01820 6.1e-255 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LKMAKOFG_01821 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LKMAKOFG_01822 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LKMAKOFG_01823 4.15e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LKMAKOFG_01824 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LKMAKOFG_01828 1.36e-117 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LKMAKOFG_01829 4.55e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LKMAKOFG_01830 1.18e-169 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LKMAKOFG_01831 1.82e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LKMAKOFG_01832 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LKMAKOFG_01833 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_01834 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_01835 8.94e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LKMAKOFG_01836 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LKMAKOFG_01837 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LKMAKOFG_01838 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LKMAKOFG_01839 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
LKMAKOFG_01840 4.1e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LKMAKOFG_01841 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LKMAKOFG_01842 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LKMAKOFG_01843 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
LKMAKOFG_01844 2.89e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LKMAKOFG_01845 1.74e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LKMAKOFG_01846 4.1e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LKMAKOFG_01847 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_01848 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKMAKOFG_01849 2.75e-100 ywbB - - S - - - Protein of unknown function (DUF2711)
LKMAKOFG_01850 7.35e-31 ywbB - - S - - - Protein of unknown function (DUF2711)
LKMAKOFG_01851 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
LKMAKOFG_01852 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LKMAKOFG_01853 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LKMAKOFG_01854 2.46e-108 yshB - - S - - - membrane protein, required for colicin V production
LKMAKOFG_01855 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LKMAKOFG_01856 3.08e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LKMAKOFG_01857 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKMAKOFG_01858 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LKMAKOFG_01859 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKMAKOFG_01860 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LKMAKOFG_01861 1.7e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
LKMAKOFG_01862 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
LKMAKOFG_01863 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LKMAKOFG_01864 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LKMAKOFG_01865 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
LKMAKOFG_01866 1.18e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
LKMAKOFG_01867 4.38e-215 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
LKMAKOFG_01868 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LKMAKOFG_01869 2.62e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LKMAKOFG_01870 1.98e-177 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LKMAKOFG_01871 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LKMAKOFG_01872 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
LKMAKOFG_01873 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LKMAKOFG_01874 8.14e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LKMAKOFG_01875 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
LKMAKOFG_01876 9.34e-88 ysdB - - S - - - Sigma-w pathway protein YsdB
LKMAKOFG_01877 1.34e-56 ysdA - - S - - - Membrane
LKMAKOFG_01878 2.3e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LKMAKOFG_01879 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LKMAKOFG_01880 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LKMAKOFG_01881 4.4e-147 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LKMAKOFG_01882 1.12e-68 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
LKMAKOFG_01883 1.05e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LKMAKOFG_01884 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_01885 1.46e-168 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LKMAKOFG_01886 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKMAKOFG_01887 4.88e-198 ytxC - - S - - - YtxC-like family
LKMAKOFG_01888 5.2e-139 ytxB - - S - - - SNARE associated Golgi protein
LKMAKOFG_01889 4.08e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LKMAKOFG_01890 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LKMAKOFG_01891 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LKMAKOFG_01892 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LKMAKOFG_01893 1.27e-248 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LKMAKOFG_01894 1.69e-89 ytcD - - K - - - Transcriptional regulator
LKMAKOFG_01895 1.61e-258 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
LKMAKOFG_01896 4.54e-205 ytbE - - S - - - reductase
LKMAKOFG_01897 1.46e-128 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LKMAKOFG_01898 2e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
LKMAKOFG_01899 1.64e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LKMAKOFG_01900 1.62e-183 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LKMAKOFG_01901 1.66e-71 - 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
LKMAKOFG_01902 1.16e-206 yisR - - K - - - Transcriptional regulator
LKMAKOFG_01903 3.19e-312 yisQ - - V - - - Mate efflux family protein
LKMAKOFG_01904 3.13e-170 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
LKMAKOFG_01905 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LKMAKOFG_01906 1.86e-124 yisN - - S - - - Protein of unknown function (DUF2777)
LKMAKOFG_01907 2.22e-78 yisL - - S - - - UPF0344 protein
LKMAKOFG_01908 1.48e-216 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LKMAKOFG_01909 1.59e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
LKMAKOFG_01910 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LKMAKOFG_01911 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
LKMAKOFG_01912 8.51e-109 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LKMAKOFG_01913 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LKMAKOFG_01914 1.67e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LKMAKOFG_01915 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LKMAKOFG_01916 2.18e-66 yisB - - V - - - COG1403 Restriction endonuclease
LKMAKOFG_01917 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
LKMAKOFG_01918 2.72e-282 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LKMAKOFG_01919 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LKMAKOFG_01920 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LKMAKOFG_01921 7.06e-160 ydfS - - S - - - Protein of unknown function (DUF421)
LKMAKOFG_01922 4.05e-119 yhjR - - S - - - Rubrerythrin
LKMAKOFG_01923 3.04e-137 - - - K - - - QacR-like protein, C-terminal region
LKMAKOFG_01924 2.17e-267 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_01925 9.85e-262 yhjN - - S ko:K07120 - ko00000 membrane
LKMAKOFG_01926 1.99e-121 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_01927 0.0 yhjG - - CH - - - FAD binding domain
LKMAKOFG_01928 6.7e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LKMAKOFG_01929 9.09e-142 yhjE - - S - - - SNARE associated Golgi protein
LKMAKOFG_01930 5.86e-79 yhjD - - - - - - -
LKMAKOFG_01931 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
LKMAKOFG_01932 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKMAKOFG_01933 2.17e-62 - - - S - - - Belongs to the UPF0145 family
LKMAKOFG_01934 2.48e-57 yhjA - - S - - - Excalibur calcium-binding domain
LKMAKOFG_01935 4.26e-161 yrpD - - S - - - Domain of unknown function, YrpD
LKMAKOFG_01936 5.53e-117 - - - S - - - MepB protein
LKMAKOFG_01937 1.53e-85 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LKMAKOFG_01938 6.54e-63 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LKMAKOFG_01939 1.09e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LKMAKOFG_01940 3.87e-42 yhzC - - S - - - IDEAL
LKMAKOFG_01941 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_01942 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LKMAKOFG_01943 4.6e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LKMAKOFG_01944 1.53e-115 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LKMAKOFG_01945 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LKMAKOFG_01946 4.29e-254 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LKMAKOFG_01947 6.03e-134 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
LKMAKOFG_01948 3.25e-195 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LKMAKOFG_01949 9.1e-261 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKMAKOFG_01950 2.15e-299 yhfN - - O - - - Peptidase M48
LKMAKOFG_01951 6.81e-86 yhfM - - - - - - -
LKMAKOFG_01952 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LKMAKOFG_01953 8.62e-141 yhfK - - GM - - - NmrA-like family
LKMAKOFG_01954 2.63e-241 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LKMAKOFG_01955 4.68e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LKMAKOFG_01956 3.36e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKMAKOFG_01957 5.19e-251 yhfE - - G - - - peptidase M42
LKMAKOFG_01959 5.92e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKMAKOFG_01960 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LKMAKOFG_01961 3.1e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_01962 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LKMAKOFG_01963 1.5e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LKMAKOFG_01964 7.35e-259 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LKMAKOFG_01965 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LKMAKOFG_01966 5.14e-116 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LKMAKOFG_01967 1.97e-311 yhfA - - C - - - membrane
LKMAKOFG_01968 1.78e-285 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LKMAKOFG_01969 1.75e-161 ecsC - - S - - - EcsC protein family
LKMAKOFG_01970 6.41e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LKMAKOFG_01971 1.5e-173 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LKMAKOFG_01972 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LKMAKOFG_01973 1.02e-259 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LKMAKOFG_01974 5.58e-100 trpP - - S - - - Tryptophan transporter TrpP
LKMAKOFG_01975 2.55e-24 - - - - - - - -
LKMAKOFG_01976 2.25e-53 yhaH - - S - - - YtxH-like protein
LKMAKOFG_01977 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LKMAKOFG_01978 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
LKMAKOFG_01979 1.29e-123 yhaK - - S - - - Putative zincin peptidase
LKMAKOFG_01980 1.66e-184 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LKMAKOFG_01981 4.95e-44 yhaL - - S - - - Sporulation protein YhaL
LKMAKOFG_01982 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LKMAKOFG_01983 0.0 yhaN - - L - - - AAA domain
LKMAKOFG_01984 4.32e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LKMAKOFG_01985 1.68e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LKMAKOFG_01986 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_01987 5.99e-21 - - - S - - - YhzD-like protein
LKMAKOFG_01988 5.83e-175 yhaR - - I - - - enoyl-CoA hydratase
LKMAKOFG_01990 8.88e-112 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LKMAKOFG_01991 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
LKMAKOFG_01992 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
LKMAKOFG_01993 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
LKMAKOFG_01994 2.95e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
LKMAKOFG_01995 1.43e-257 yhaZ - - L - - - DNA alkylation repair enzyme
LKMAKOFG_01996 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
LKMAKOFG_01997 6.44e-263 yheB - - S - - - Belongs to the UPF0754 family
LKMAKOFG_01998 1.08e-272 yheC - - HJ - - - YheC/D like ATP-grasp
LKMAKOFG_01999 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LKMAKOFG_02000 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
LKMAKOFG_02001 1.15e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
LKMAKOFG_02003 1.35e-140 yheG - - GM - - - NAD(P)H-binding
LKMAKOFG_02004 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKMAKOFG_02005 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKMAKOFG_02007 2.49e-110 - - - T - - - universal stress protein
LKMAKOFG_02008 1.81e-122 ymcC - - S - - - Membrane
LKMAKOFG_02009 1.74e-114 pksA - - K - - - Transcriptional regulator
LKMAKOFG_02010 2.41e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LKMAKOFG_02011 6.94e-201 nodB1 - - G - - - deacetylase
LKMAKOFG_02012 7.18e-181 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LKMAKOFG_02013 1.29e-259 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
LKMAKOFG_02014 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
LKMAKOFG_02015 1.56e-166 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LKMAKOFG_02016 5.57e-76 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKMAKOFG_02017 5.01e-71 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LKMAKOFG_02018 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
LKMAKOFG_02019 2.24e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKMAKOFG_02020 4.05e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LKMAKOFG_02021 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LKMAKOFG_02022 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LKMAKOFG_02023 1.86e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LKMAKOFG_02024 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKMAKOFG_02025 1.69e-257 yhdL - - S - - - Sigma factor regulator N-terminal
LKMAKOFG_02026 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
LKMAKOFG_02027 2.94e-267 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKMAKOFG_02028 4.45e-316 yhdG - - E ko:K03294 - ko00000 amino acid
LKMAKOFG_02029 7.83e-206 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_02030 4.69e-261 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LKMAKOFG_02031 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_02032 6.44e-177 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LKMAKOFG_02033 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LKMAKOFG_02034 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LKMAKOFG_02035 0.0 ygxB - - M - - - Conserved TM helix
LKMAKOFG_02036 1.32e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LKMAKOFG_02037 4.93e-296 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LKMAKOFG_02038 2.42e-70 yhdC - - S - - - Protein of unknown function (DUF3889)
LKMAKOFG_02039 6.98e-53 yhdB - - S - - - YhdB-like protein
LKMAKOFG_02040 1.97e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
LKMAKOFG_02041 6.35e-143 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_02042 3.72e-263 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_02043 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LKMAKOFG_02044 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LKMAKOFG_02045 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LKMAKOFG_02046 2.83e-199 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LKMAKOFG_02047 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LKMAKOFG_02048 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKMAKOFG_02049 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LKMAKOFG_02050 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
LKMAKOFG_02051 2.5e-90 yhcV - - S - - - COG0517 FOG CBS domain
LKMAKOFG_02052 3.12e-91 yhcU - - S - - - Family of unknown function (DUF5365)
LKMAKOFG_02053 2.27e-216 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LKMAKOFG_02054 1.3e-136 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
LKMAKOFG_02055 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LKMAKOFG_02056 5.2e-150 yhcQ - - M - - - Spore coat protein
LKMAKOFG_02057 1.46e-202 yhcP - - - - - - -
LKMAKOFG_02058 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LKMAKOFG_02059 1.58e-79 yhcM - - - - - - -
LKMAKOFG_02060 1.23e-291 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LKMAKOFG_02061 2.48e-235 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
LKMAKOFG_02062 5.86e-190 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LKMAKOFG_02063 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
LKMAKOFG_02064 1.57e-209 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LKMAKOFG_02065 2.75e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_02066 4.89e-160 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_02067 6.97e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_02068 3.76e-65 - - - - - - - -
LKMAKOFG_02069 5.75e-72 yhcC - - - - - - -
LKMAKOFG_02070 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LKMAKOFG_02071 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
LKMAKOFG_02072 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
LKMAKOFG_02073 4.15e-98 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
LKMAKOFG_02074 5.45e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
LKMAKOFG_02075 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LKMAKOFG_02076 1.23e-07 - - - - - - - -
LKMAKOFG_02077 2.02e-94 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LKMAKOFG_02078 8.53e-87 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LKMAKOFG_02079 1.09e-137 yhbD - - K - - - Protein of unknown function (DUF4004)
LKMAKOFG_02080 4.84e-112 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LKMAKOFG_02081 1.21e-224 yhbB - - S - - - Putative amidase domain
LKMAKOFG_02082 2.08e-287 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LKMAKOFG_02083 2.73e-147 yhzB - - S - - - B3/4 domain
LKMAKOFG_02085 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_02086 2.6e-106 ygaO - - - - - - -
LKMAKOFG_02087 1.18e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKMAKOFG_02088 3e-273 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LKMAKOFG_02089 1.17e-185 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LKMAKOFG_02090 4.3e-230 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
LKMAKOFG_02091 1.29e-179 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LKMAKOFG_02092 4.68e-234 - - - S ko:K07045 - ko00000 Amidohydrolase
LKMAKOFG_02093 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LKMAKOFG_02094 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02095 1.56e-169 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02096 1.77e-161 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKMAKOFG_02097 2.09e-188 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKMAKOFG_02098 7.75e-292 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
LKMAKOFG_02100 0.0 ygaK - - C - - - Berberine and berberine like
LKMAKOFG_02101 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LKMAKOFG_02102 1.29e-171 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LKMAKOFG_02103 0.0 - - - C - - - Na+/H+ antiporter family
LKMAKOFG_02120 1.15e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
LKMAKOFG_02121 2.63e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LKMAKOFG_02122 7.47e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LKMAKOFG_02123 2.81e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LKMAKOFG_02124 1.02e-235 spsG - - M - - - Spore Coat
LKMAKOFG_02125 4.11e-171 spsF - - M ko:K07257 - ko00000 Spore Coat
LKMAKOFG_02126 1.23e-274 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
LKMAKOFG_02127 1.3e-203 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
LKMAKOFG_02128 6.91e-280 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LKMAKOFG_02129 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
LKMAKOFG_02130 9.06e-184 spsA - - M - - - Spore Coat
LKMAKOFG_02131 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LKMAKOFG_02132 2.17e-76 ywdK - - S - - - small membrane protein
LKMAKOFG_02133 1.13e-292 ywdJ - - F - - - Xanthine uracil
LKMAKOFG_02134 3.54e-61 ywdI - - S - - - Family of unknown function (DUF5327)
LKMAKOFG_02135 7.22e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LKMAKOFG_02136 7.76e-191 ywdF - - S - - - Glycosyltransferase like family 2
LKMAKOFG_02138 1.35e-113 ywdD - - - - - - -
LKMAKOFG_02139 1.32e-74 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LKMAKOFG_02140 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LKMAKOFG_02141 3.52e-26 ywdA - - - - - - -
LKMAKOFG_02142 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LKMAKOFG_02143 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_02145 4.68e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LKMAKOFG_02147 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKMAKOFG_02148 4.69e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKMAKOFG_02149 3.83e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LKMAKOFG_02150 7.63e-271 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LKMAKOFG_02151 7.46e-101 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
LKMAKOFG_02152 2.54e-51 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
LKMAKOFG_02153 1.31e-81 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LKMAKOFG_02154 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LKMAKOFG_02155 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LKMAKOFG_02156 3.14e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LKMAKOFG_02157 5.74e-48 ydaS - - S - - - membrane
LKMAKOFG_02158 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LKMAKOFG_02159 3.62e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LKMAKOFG_02160 2e-80 gtcA - - S - - - GtrA-like protein
LKMAKOFG_02161 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
LKMAKOFG_02163 3.05e-167 - - - H - - - Methionine biosynthesis protein MetW
LKMAKOFG_02164 4.52e-168 - - - S - - - Streptomycin biosynthesis protein StrF
LKMAKOFG_02165 3.09e-145 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LKMAKOFG_02166 3.62e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
LKMAKOFG_02167 1.12e-143 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LKMAKOFG_02168 3.73e-175 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LKMAKOFG_02169 1.97e-201 ywbI - - K - - - Transcriptional regulator
LKMAKOFG_02170 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LKMAKOFG_02171 6.47e-144 ywbG - - M - - - effector of murein hydrolase
LKMAKOFG_02172 9.1e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
LKMAKOFG_02173 1.39e-181 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LKMAKOFG_02174 2.36e-217 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LKMAKOFG_02175 5.11e-285 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
LKMAKOFG_02176 1.51e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
LKMAKOFG_02177 4.68e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKMAKOFG_02178 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LKMAKOFG_02179 3.64e-208 gspA - - M - - - General stress
LKMAKOFG_02180 1.76e-64 ywaE - - K - - - Transcriptional regulator
LKMAKOFG_02181 1.74e-249 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKMAKOFG_02182 5.29e-151 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LKMAKOFG_02183 4.37e-214 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LKMAKOFG_02184 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
LKMAKOFG_02185 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02186 2.56e-293 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
LKMAKOFG_02187 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02188 3.09e-289 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LKMAKOFG_02189 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LKMAKOFG_02190 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKMAKOFG_02191 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_02192 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKMAKOFG_02193 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
LKMAKOFG_02194 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LKMAKOFG_02195 4.59e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LKMAKOFG_02196 2e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_02197 1.96e-230 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_02198 1.86e-213 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LKMAKOFG_02199 1.07e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
LKMAKOFG_02200 1.47e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKMAKOFG_02201 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_02202 3.22e-65 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_02203 8.53e-304 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKMAKOFG_02204 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKMAKOFG_02205 5.14e-213 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LKMAKOFG_02206 1.3e-237 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LKMAKOFG_02207 5.32e-267 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LKMAKOFG_02208 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LKMAKOFG_02209 2.26e-245 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LKMAKOFG_02210 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LKMAKOFG_02211 1.46e-199 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LKMAKOFG_02212 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LKMAKOFG_02213 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LKMAKOFG_02214 1.12e-241 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LKMAKOFG_02215 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LKMAKOFG_02216 2.74e-288 cimH - - C - - - COG3493 Na citrate symporter
LKMAKOFG_02217 4.31e-196 yxkH - - G - - - Polysaccharide deacetylase
LKMAKOFG_02218 1.1e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02219 1.85e-208 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LKMAKOFG_02220 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKMAKOFG_02221 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
LKMAKOFG_02222 2.28e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LKMAKOFG_02223 4.68e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LKMAKOFG_02226 2.49e-110 yxjI - - S - - - LURP-one-related
LKMAKOFG_02227 8.03e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LKMAKOFG_02228 6.72e-209 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
LKMAKOFG_02229 5.49e-266 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKMAKOFG_02230 5.15e-117 - - - T - - - Domain of unknown function (DUF4163)
LKMAKOFG_02231 2.68e-67 yxiS - - - - - - -
LKMAKOFG_02232 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LKMAKOFG_02233 1.11e-281 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LKMAKOFG_02234 1.91e-183 bglS - - M - - - licheninase activity
LKMAKOFG_02235 3.01e-281 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
LKMAKOFG_02236 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LKMAKOFG_02238 1.61e-28 - - - - - - - -
LKMAKOFG_02240 1.32e-132 - - - - - - - -
LKMAKOFG_02241 2.48e-96 - - - - - - - -
LKMAKOFG_02242 1.05e-27 - - - - - - - -
LKMAKOFG_02245 4.21e-91 yxiG - - - - - - -
LKMAKOFG_02246 0.0 wapA - - M - - - COG3209 Rhs family protein
LKMAKOFG_02247 3.02e-254 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LKMAKOFG_02248 1.03e-208 yxxF - - EG - - - EamA-like transporter family
LKMAKOFG_02249 2.44e-94 yxiE - - T - - - Belongs to the universal stress protein A family
LKMAKOFG_02250 1.15e-78 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKMAKOFG_02251 0.0 - - - L - - - HKD family nuclease
LKMAKOFG_02252 2.39e-85 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LKMAKOFG_02253 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LKMAKOFG_02254 1.42e-102 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LKMAKOFG_02255 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
LKMAKOFG_02256 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LKMAKOFG_02257 1.57e-299 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
LKMAKOFG_02258 6.83e-225 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LKMAKOFG_02259 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKMAKOFG_02260 6.37e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LKMAKOFG_02261 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LKMAKOFG_02262 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LKMAKOFG_02263 5.8e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LKMAKOFG_02264 2.32e-193 yxeH - - S - - - hydrolases of the HAD superfamily
LKMAKOFG_02267 5.59e-40 yxeE - - - - - - -
LKMAKOFG_02268 5.09e-35 yxeD - - - - - - -
LKMAKOFG_02269 1.97e-46 - - - - - - - -
LKMAKOFG_02270 2.29e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LKMAKOFG_02271 4.9e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
LKMAKOFG_02272 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LKMAKOFG_02273 4.65e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_02274 1.37e-224 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_02275 9.37e-159 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_02276 1.83e-200 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LKMAKOFG_02277 2.95e-201 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LKMAKOFG_02278 2.97e-210 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LKMAKOFG_02279 5.18e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LKMAKOFG_02280 1.5e-293 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LKMAKOFG_02281 4.62e-223 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LKMAKOFG_02282 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LKMAKOFG_02283 2.3e-230 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LKMAKOFG_02284 3.45e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LKMAKOFG_02285 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKMAKOFG_02286 6.09e-175 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LKMAKOFG_02287 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LKMAKOFG_02288 4.5e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKMAKOFG_02289 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LKMAKOFG_02291 3.56e-194 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LKMAKOFG_02292 7.5e-132 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_02293 2.49e-256 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_02294 3.53e-255 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LKMAKOFG_02295 3.13e-274 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LKMAKOFG_02297 7.81e-264 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKMAKOFG_02298 8.32e-190 yxaL - - S - - - PQQ-like domain
LKMAKOFG_02299 1.19e-83 - - - S - - - Family of unknown function (DUF5391)
LKMAKOFG_02300 4.94e-67 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LKMAKOFG_02301 9.35e-257 - - - EGP - - - Major Facilitator Superfamily
LKMAKOFG_02302 8.75e-94 yxaI - - S - - - membrane protein domain
LKMAKOFG_02303 2.7e-162 - - - E - - - Ring-cleavage extradiol dioxygenase
LKMAKOFG_02304 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LKMAKOFG_02305 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LKMAKOFG_02306 6.78e-129 - - - S - - - Fic/DOC family
LKMAKOFG_02328 2.9e-99 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
LKMAKOFG_02329 6.11e-169 yteA - - T - - - COG1734 DnaK suppressor protein
LKMAKOFG_02330 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LKMAKOFG_02331 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LKMAKOFG_02332 4.36e-200 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LKMAKOFG_02333 7.52e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LKMAKOFG_02334 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LKMAKOFG_02335 1.17e-271 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LKMAKOFG_02336 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
LKMAKOFG_02337 1.22e-232 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LKMAKOFG_02338 1.82e-312 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LKMAKOFG_02339 1.23e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LKMAKOFG_02340 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LKMAKOFG_02341 1.99e-52 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
LKMAKOFG_02342 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LKMAKOFG_02343 7.31e-100 ytkA - - S - - - YtkA-like
LKMAKOFG_02345 2.56e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LKMAKOFG_02346 1.01e-78 ytkC - - S - - - Bacteriophage holin family
LKMAKOFG_02347 1.01e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LKMAKOFG_02348 2.68e-167 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LKMAKOFG_02349 5.87e-182 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKMAKOFG_02350 2.62e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LKMAKOFG_02351 3.71e-188 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LKMAKOFG_02352 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
LKMAKOFG_02353 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LKMAKOFG_02354 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LKMAKOFG_02355 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LKMAKOFG_02356 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKMAKOFG_02357 1.65e-83 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LKMAKOFG_02358 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LKMAKOFG_02359 2.02e-271 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LKMAKOFG_02360 4.99e-183 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
LKMAKOFG_02362 2.55e-136 ytqB - - J - - - Putative rRNA methylase
LKMAKOFG_02363 1.65e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
LKMAKOFG_02364 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
LKMAKOFG_02366 5.41e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
LKMAKOFG_02367 4.38e-209 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_02368 1.73e-224 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LKMAKOFG_02369 3.56e-233 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LKMAKOFG_02370 4.46e-210 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
LKMAKOFG_02371 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_02372 1.93e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LKMAKOFG_02373 9.07e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_02374 2.66e-216 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
LKMAKOFG_02375 4.63e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_02376 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
LKMAKOFG_02377 5.17e-161 ywaF - - S - - - Integral membrane protein
LKMAKOFG_02378 7.89e-268 yttB - - EGP - - - Major facilitator superfamily
LKMAKOFG_02379 2.77e-176 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LKMAKOFG_02380 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
LKMAKOFG_02381 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LKMAKOFG_02382 8.6e-69 ytwF - - P - - - Sulfurtransferase
LKMAKOFG_02383 2.41e-111 - - - M - - - Acetyltransferase (GNAT) domain
LKMAKOFG_02384 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LKMAKOFG_02385 4.78e-183 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LKMAKOFG_02386 2.54e-214 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LKMAKOFG_02387 6.55e-310 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LKMAKOFG_02388 7.81e-239 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_02389 2.14e-36 yteV - - S - - - Sporulation protein Cse60
LKMAKOFG_02390 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
LKMAKOFG_02391 2.16e-298 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
LKMAKOFG_02392 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKMAKOFG_02393 3.53e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LKMAKOFG_02394 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LKMAKOFG_02395 1.28e-163 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LKMAKOFG_02396 4.3e-277 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
LKMAKOFG_02397 6.04e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
LKMAKOFG_02398 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LKMAKOFG_02399 4.6e-220 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LKMAKOFG_02400 4.46e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LKMAKOFG_02401 2.97e-216 ytlQ - - - - - - -
LKMAKOFG_02402 1.68e-226 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LKMAKOFG_02403 2.93e-199 ytmP - - M - - - Phosphotransferase
LKMAKOFG_02404 5.51e-60 ytzH - - S - - - YtzH-like protein
LKMAKOFG_02405 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LKMAKOFG_02406 5.33e-209 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKMAKOFG_02407 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LKMAKOFG_02408 9.96e-69 ytzB - - S - - - small secreted protein
LKMAKOFG_02409 8.74e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LKMAKOFG_02410 5.77e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LKMAKOFG_02411 5.47e-76 ytpP - - CO - - - Thioredoxin
LKMAKOFG_02412 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
LKMAKOFG_02413 8.47e-139 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LKMAKOFG_02414 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LKMAKOFG_02415 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LKMAKOFG_02416 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKMAKOFG_02417 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
LKMAKOFG_02418 2.93e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
LKMAKOFG_02419 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LKMAKOFG_02420 5.91e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LKMAKOFG_02421 2.12e-185 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LKMAKOFG_02422 1.05e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LKMAKOFG_02423 1.94e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LKMAKOFG_02424 2.93e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LKMAKOFG_02425 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LKMAKOFG_02426 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKMAKOFG_02427 5.73e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LKMAKOFG_02428 8.79e-64 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
LKMAKOFG_02429 2.86e-160 ygaZ - - E - - - AzlC protein
LKMAKOFG_02430 4.49e-190 - - - K - - - Transcriptional regulator
LKMAKOFG_02431 4.99e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKMAKOFG_02432 1.02e-177 - - - E - - - GDSL-like Lipase/Acylhydrolase family
LKMAKOFG_02434 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LKMAKOFG_02436 1.11e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LKMAKOFG_02437 2.12e-131 yokH - - G - - - SMI1 / KNR4 family
LKMAKOFG_02438 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKMAKOFG_02439 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LKMAKOFG_02440 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LKMAKOFG_02441 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LKMAKOFG_02442 2.41e-141 yttP - - K - - - Transcriptional regulator
LKMAKOFG_02443 2.42e-195 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LKMAKOFG_02444 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LKMAKOFG_02445 9.7e-309 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LKMAKOFG_02446 9.17e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LKMAKOFG_02447 1.72e-286 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LKMAKOFG_02448 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
LKMAKOFG_02449 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LKMAKOFG_02450 0.0 ytcJ - - S - - - amidohydrolase
LKMAKOFG_02451 1.91e-195 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKMAKOFG_02452 2.6e-234 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LKMAKOFG_02453 1.6e-113 yteJ - - S - - - RDD family
LKMAKOFG_02454 1.22e-154 ytfI - - S - - - Protein of unknown function (DUF2953)
LKMAKOFG_02455 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
LKMAKOFG_02456 7.88e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LKMAKOFG_02457 5.89e-232 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LKMAKOFG_02458 2.71e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LKMAKOFG_02459 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LKMAKOFG_02460 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LKMAKOFG_02461 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LKMAKOFG_02463 2.06e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_02464 4.16e-166 ytkL - - S - - - Belongs to the UPF0173 family
LKMAKOFG_02465 1.94e-304 ytoI - - K - - - transcriptional regulator containing CBS domains
LKMAKOFG_02466 3.57e-62 ytpI - - S - - - YtpI-like protein
LKMAKOFG_02467 2.14e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LKMAKOFG_02468 1e-31 - - - - - - - -
LKMAKOFG_02469 2.64e-114 ytrI - - - - - - -
LKMAKOFG_02470 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
LKMAKOFG_02471 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LKMAKOFG_02472 4.23e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LKMAKOFG_02473 8.46e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LKMAKOFG_02474 3.28e-232 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LKMAKOFG_02475 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LKMAKOFG_02476 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LKMAKOFG_02477 2.41e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
LKMAKOFG_02478 4.05e-247 ytvI - - S - - - sporulation integral membrane protein YtvI
LKMAKOFG_02479 5.65e-96 ytwI - - S - - - membrane
LKMAKOFG_02480 3.72e-81 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LKMAKOFG_02481 3.87e-69 - - - - - - - -
LKMAKOFG_02483 2.02e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LKMAKOFG_02484 5.36e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LKMAKOFG_02485 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LKMAKOFG_02486 4.82e-166 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_02487 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LKMAKOFG_02489 5.16e-115 yisT - - S - - - DinB family
LKMAKOFG_02490 1.13e-103 yisX - - S - - - Pentapeptide repeats (9 copies)
LKMAKOFG_02491 1.08e-105 - - - S - - - Acetyltransferase (GNAT) domain
LKMAKOFG_02492 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LKMAKOFG_02493 3.69e-78 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
LKMAKOFG_02494 1.85e-205 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LKMAKOFG_02495 1.32e-222 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
LKMAKOFG_02496 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LKMAKOFG_02497 3.61e-307 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LKMAKOFG_02499 5.5e-203 yitS - - S - - - protein conserved in bacteria
LKMAKOFG_02500 4.62e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKMAKOFG_02501 3.71e-105 ipi - - S - - - Intracellular proteinase inhibitor
LKMAKOFG_02502 3.02e-36 - - - S - - - Protein of unknown function (DUF3813)
LKMAKOFG_02503 1.49e-11 - - - - - - - -
LKMAKOFG_02504 4.18e-196 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LKMAKOFG_02505 4.33e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LKMAKOFG_02506 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LKMAKOFG_02507 5.48e-100 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LKMAKOFG_02508 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
LKMAKOFG_02509 2.39e-121 yitZ - - G - - - Major Facilitator Superfamily
LKMAKOFG_02510 8.29e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LKMAKOFG_02511 4.95e-288 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LKMAKOFG_02512 1.27e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LKMAKOFG_02513 4.84e-278 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LKMAKOFG_02514 1.98e-258 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LKMAKOFG_02515 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LKMAKOFG_02516 6.8e-224 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LKMAKOFG_02517 7.21e-39 yjzC - - S - - - YjzC-like protein
LKMAKOFG_02518 5.24e-33 yjzD - - S - - - Protein of unknown function (DUF2929)
LKMAKOFG_02519 1.83e-177 yjaU - - I - - - carboxylic ester hydrolase activity
LKMAKOFG_02520 5.83e-135 yjaV - - - - - - -
LKMAKOFG_02521 4.67e-213 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
LKMAKOFG_02522 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
LKMAKOFG_02523 1.63e-43 yjzB - - - - - - -
LKMAKOFG_02524 2.19e-219 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LKMAKOFG_02525 3.86e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKMAKOFG_02526 7.48e-190 yjaZ - - O - - - Zn-dependent protease
LKMAKOFG_02527 8.37e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02528 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02529 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LKMAKOFG_02530 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKMAKOFG_02531 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKMAKOFG_02532 1.07e-188 yjbA - - S - - - Belongs to the UPF0736 family
LKMAKOFG_02533 8.74e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LKMAKOFG_02534 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LKMAKOFG_02535 2.53e-213 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKMAKOFG_02536 8.44e-209 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LKMAKOFG_02537 1.5e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02538 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02539 1.66e-293 - - - S - - - Putative glycosyl hydrolase domain
LKMAKOFG_02540 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKMAKOFG_02541 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LKMAKOFG_02542 3.23e-140 yjbE - - P - - - Integral membrane protein TerC family
LKMAKOFG_02543 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LKMAKOFG_02544 2.32e-281 coiA - - S ko:K06198 - ko00000 Competence protein
LKMAKOFG_02545 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LKMAKOFG_02546 3.14e-27 - - - - - - - -
LKMAKOFG_02547 1.22e-219 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LKMAKOFG_02548 2.03e-92 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
LKMAKOFG_02549 3.12e-152 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKMAKOFG_02550 1.72e-128 yjbK - - S - - - protein conserved in bacteria
LKMAKOFG_02551 3.93e-78 yjbL - - S - - - Belongs to the UPF0738 family
LKMAKOFG_02552 1.56e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LKMAKOFG_02553 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LKMAKOFG_02554 9.96e-213 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LKMAKOFG_02555 2.15e-183 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LKMAKOFG_02556 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LKMAKOFG_02557 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LKMAKOFG_02558 8.09e-139 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
LKMAKOFG_02559 6.49e-268 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
LKMAKOFG_02560 6.44e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
LKMAKOFG_02561 5.18e-173 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LKMAKOFG_02562 1.52e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LKMAKOFG_02563 1.5e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LKMAKOFG_02564 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LKMAKOFG_02565 2.9e-126 yjbX - - S - - - Spore coat protein
LKMAKOFG_02566 1.12e-103 cotZ - - S ko:K06344 - ko00000 Spore coat protein
LKMAKOFG_02567 1.96e-117 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
LKMAKOFG_02568 2.33e-103 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
LKMAKOFG_02569 1.98e-36 cotW - - - ko:K06341 - ko00000 -
LKMAKOFG_02570 8.66e-74 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
LKMAKOFG_02571 8.37e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
LKMAKOFG_02574 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LKMAKOFG_02575 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
LKMAKOFG_02576 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKMAKOFG_02577 4.12e-47 - - - - - - - -
LKMAKOFG_02578 5.44e-177 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
LKMAKOFG_02579 3.23e-160 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
LKMAKOFG_02580 4.12e-170 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LKMAKOFG_02581 4.32e-48 - - - K - - - SpoVT / AbrB like domain
LKMAKOFG_02582 1.01e-95 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LKMAKOFG_02583 6.97e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LKMAKOFG_02584 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LKMAKOFG_02585 3.93e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LKMAKOFG_02586 4.67e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LKMAKOFG_02588 3.29e-28 - - - - - - - -
LKMAKOFG_02589 0.0 - - - S - - - Bacterial EndoU nuclease
LKMAKOFG_02592 3.82e-77 - - - E - - - Glyoxalase-like domain
LKMAKOFG_02593 1.11e-208 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
LKMAKOFG_02594 1.27e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LKMAKOFG_02595 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
LKMAKOFG_02596 1.06e-106 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_02597 1.82e-279 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LKMAKOFG_02598 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LKMAKOFG_02599 3.46e-241 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LKMAKOFG_02600 3.67e-275 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LKMAKOFG_02601 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LKMAKOFG_02602 1.48e-65 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_02603 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKMAKOFG_02604 1.39e-177 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LKMAKOFG_02605 2.4e-160 - - - S - - - Haloacid dehalogenase-like hydrolase
LKMAKOFG_02606 6.86e-46 - - - - - - - -
LKMAKOFG_02607 2.4e-68 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_02608 2.48e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LKMAKOFG_02609 1.91e-31 yjfB - - S - - - Putative motility protein
LKMAKOFG_02610 2.98e-90 yjgA - - T - - - Protein of unknown function (DUF2809)
LKMAKOFG_02611 4.58e-128 yjgB - - S - - - Domain of unknown function (DUF4309)
LKMAKOFG_02612 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
LKMAKOFG_02613 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
LKMAKOFG_02614 1.09e-289 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKMAKOFG_02615 2e-284 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LKMAKOFG_02616 1.73e-40 - - - - - - - -
LKMAKOFG_02617 9.72e-187 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LKMAKOFG_02618 1.2e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
LKMAKOFG_02619 2.64e-167 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
LKMAKOFG_02620 2.38e-226 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LKMAKOFG_02621 2.1e-119 yjlB - - S - - - Cupin domain
LKMAKOFG_02622 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
LKMAKOFG_02623 1.76e-279 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LKMAKOFG_02624 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LKMAKOFG_02625 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
LKMAKOFG_02626 1.77e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
LKMAKOFG_02627 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LKMAKOFG_02628 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LKMAKOFG_02629 1.06e-111 - - - T - - - Transcriptional regulatory protein, C terminal
LKMAKOFG_02630 6.96e-167 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LKMAKOFG_02631 1.11e-132 - - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_02632 5.45e-05 - - - S - - - ABC-2 family transporter protein
LKMAKOFG_02633 4.85e-64 - - - S - - - ABC-2 family transporter protein
LKMAKOFG_02635 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LKMAKOFG_02636 3.29e-67 - - - K - - - Helix-turn-helix domain
LKMAKOFG_02637 6.82e-256 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
LKMAKOFG_02638 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LKMAKOFG_02639 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
LKMAKOFG_02640 1.62e-124 - - - L - - - Integrase
LKMAKOFG_02642 2.49e-123 yoeB - - S - - - IseA DL-endopeptidase inhibitor
LKMAKOFG_02643 7.44e-312 yoeA - - V - - - MATE efflux family protein
LKMAKOFG_02644 5.4e-169 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LKMAKOFG_02645 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LKMAKOFG_02646 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02647 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02648 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02649 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02650 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
LKMAKOFG_02651 1.38e-84 yngL - - S - - - Protein of unknown function (DUF1360)
LKMAKOFG_02652 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
LKMAKOFG_02653 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LKMAKOFG_02654 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LKMAKOFG_02655 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LKMAKOFG_02656 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LKMAKOFG_02657 4.06e-213 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LKMAKOFG_02658 1.01e-177 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LKMAKOFG_02659 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LKMAKOFG_02660 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
LKMAKOFG_02661 1.52e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LKMAKOFG_02662 2.26e-95 yngA - - S - - - membrane
LKMAKOFG_02663 9.06e-186 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LKMAKOFG_02664 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LKMAKOFG_02665 5.38e-271 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LKMAKOFG_02666 2.14e-166 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LKMAKOFG_02667 1.12e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LKMAKOFG_02668 5.08e-282 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKMAKOFG_02669 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LKMAKOFG_02670 8.91e-162 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LKMAKOFG_02671 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKMAKOFG_02672 2.89e-178 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LKMAKOFG_02673 3.35e-288 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKMAKOFG_02674 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02675 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02676 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LKMAKOFG_02677 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LKMAKOFG_02678 0.0 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
LKMAKOFG_02679 2.67e-164 - - - T - - - Transcriptional regulatory protein, C terminal
LKMAKOFG_02680 2.41e-312 - - - T - - - Histidine kinase
LKMAKOFG_02681 4.98e-68 yvlA - - S - - - Domain of unknown function (DUF4870)
LKMAKOFG_02682 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
LKMAKOFG_02683 6.1e-272 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
LKMAKOFG_02686 1.34e-80 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LKMAKOFG_02687 5.58e-95 - - - S ko:K02004 - ko00000,ko00002,ko02000 bacteriocin-associated integral membrane protein
LKMAKOFG_02692 1.85e-173 - - - S - - - COG0457 FOG TPR repeat
LKMAKOFG_02694 2.99e-34 - - - - - - - -
LKMAKOFG_02696 3.68e-52 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
LKMAKOFG_02698 6.72e-165 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
LKMAKOFG_02699 1.35e-206 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKMAKOFG_02700 4.5e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
LKMAKOFG_02701 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LKMAKOFG_02702 4.34e-48 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
LKMAKOFG_02703 2.98e-308 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
LKMAKOFG_02704 1.06e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
LKMAKOFG_02705 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
LKMAKOFG_02706 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LKMAKOFG_02707 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_02708 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
LKMAKOFG_02709 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
LKMAKOFG_02710 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
LKMAKOFG_02711 4.81e-294 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LKMAKOFG_02712 2.47e-101 nucB - - M - - - Deoxyribonuclease NucA/NucB
LKMAKOFG_02713 1.49e-151 yoaK - - S - - - Membrane
LKMAKOFG_02714 2.78e-82 ymzB - - - - - - -
LKMAKOFG_02715 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
LKMAKOFG_02716 6.08e-06 - - - - - - - -
LKMAKOFG_02717 1.55e-160 ymaC - - S - - - Replication protein
LKMAKOFG_02718 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LKMAKOFG_02719 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LKMAKOFG_02720 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LKMAKOFG_02722 5.96e-77 ymaF - - S - - - YmaF family
LKMAKOFG_02723 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LKMAKOFG_02724 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LKMAKOFG_02725 6e-59 - - - - - - - -
LKMAKOFG_02726 9.42e-29 ymzA - - - - - - -
LKMAKOFG_02727 1.61e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LKMAKOFG_02728 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKMAKOFG_02729 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LKMAKOFG_02730 2.24e-141 ymaB - - S - - - MutT family
LKMAKOFG_02731 3.22e-150 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LKMAKOFG_02732 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LKMAKOFG_02733 2.7e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LKMAKOFG_02734 4.1e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LKMAKOFG_02735 4.39e-88 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LKMAKOFG_02736 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LKMAKOFG_02737 2.85e-268 mrjp - - G - - - Major royal jelly protein
LKMAKOFG_02738 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
LKMAKOFG_02739 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LKMAKOFG_02740 1.05e-276 xylR - - GK - - - ROK family
LKMAKOFG_02741 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LKMAKOFG_02742 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LKMAKOFG_02743 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LKMAKOFG_02746 2.21e-27 - - - - - - - -
LKMAKOFG_02747 2.83e-71 dinB - - S - - - DinB family
LKMAKOFG_02748 1.7e-236 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
LKMAKOFG_02749 5.97e-95 - - - S - - - Bacterial transferase hexapeptide (six repeats)
LKMAKOFG_02750 6.73e-23 - - - - - - - -
LKMAKOFG_02751 2.59e-160 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LKMAKOFG_02752 1.5e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LKMAKOFG_02754 1.83e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LKMAKOFG_02755 1.31e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LKMAKOFG_02756 6.28e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LKMAKOFG_02757 3.66e-108 ywmF - - S - - - Peptidase M50
LKMAKOFG_02758 2.01e-16 csbD - - K - - - CsbD-like
LKMAKOFG_02759 1.94e-66 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
LKMAKOFG_02760 1.07e-81 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
LKMAKOFG_02761 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LKMAKOFG_02762 1.08e-88 ywnA - - K - - - Transcriptional regulator
LKMAKOFG_02763 1.03e-154 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
LKMAKOFG_02764 6.88e-80 ywnC - - S - - - Family of unknown function (DUF5362)
LKMAKOFG_02765 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKMAKOFG_02766 6.01e-89 ywnF - - S - - - Family of unknown function (DUF5392)
LKMAKOFG_02768 2.76e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LKMAKOFG_02769 2.17e-187 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LKMAKOFG_02770 4.67e-95 ywnJ - - S - - - VanZ like family
LKMAKOFG_02771 1.17e-131 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LKMAKOFG_02772 1.35e-263 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LKMAKOFG_02773 3.06e-75 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
LKMAKOFG_02774 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
LKMAKOFG_02775 9.29e-132 yjgF - - Q - - - Isochorismatase family
LKMAKOFG_02776 8.05e-312 ywoD - - EGP - - - Major facilitator superfamily
LKMAKOFG_02777 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
LKMAKOFG_02778 5.82e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_02779 3.58e-93 ywoH - - K - - - transcriptional
LKMAKOFG_02780 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LKMAKOFG_02781 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LKMAKOFG_02782 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LKMAKOFG_02783 4.45e-186 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LKMAKOFG_02784 1.01e-245 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
LKMAKOFG_02785 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LKMAKOFG_02786 1.87e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LKMAKOFG_02787 2.63e-90 ywpF - - S - - - YwpF-like protein
LKMAKOFG_02788 4.49e-82 ywpG - - - - - - -
LKMAKOFG_02789 1.47e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LKMAKOFG_02790 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
LKMAKOFG_02791 2.51e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LKMAKOFG_02792 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LKMAKOFG_02793 0.0 ywqB - - S - - - SWIM zinc finger
LKMAKOFG_02794 1.74e-21 - - - - - - - -
LKMAKOFG_02795 1.18e-150 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LKMAKOFG_02796 7.39e-156 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LKMAKOFG_02797 3.03e-181 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LKMAKOFG_02798 1.02e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LKMAKOFG_02799 9.83e-191 ywqG - - S - - - Domain of unknown function (DUF1963)
LKMAKOFG_02802 2.09e-50 ywqI - - S - - - Family of unknown function (DUF5344)
LKMAKOFG_02803 0.0 ywqJ - - S - - - Pre-toxin TG
LKMAKOFG_02804 3.84e-136 - - - S - - - Domain of unknown function (DUF1851)
LKMAKOFG_02805 6.74e-86 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
LKMAKOFG_02806 8.9e-96 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
LKMAKOFG_02807 1.6e-117 - - - - - - - -
LKMAKOFG_02808 3.98e-169 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LKMAKOFG_02809 1.98e-201 - - - K - - - Transcriptional regulator
LKMAKOFG_02810 1.01e-118 ywqN - - S - - - NAD(P)H-dependent
LKMAKOFG_02812 7.09e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LKMAKOFG_02813 1.2e-131 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LKMAKOFG_02814 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LKMAKOFG_02815 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LKMAKOFG_02816 6.68e-143 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LKMAKOFG_02817 7.2e-21 - - - - - - - -
LKMAKOFG_02818 6.23e-268 cotH - - M ko:K06330 - ko00000 Spore Coat
LKMAKOFG_02819 1.76e-183 cotB - - - ko:K06325 - ko00000 -
LKMAKOFG_02820 1.98e-162 ywrJ - - - - - - -
LKMAKOFG_02821 8.57e-306 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LKMAKOFG_02823 5.35e-215 alsR - - K - - - LysR substrate binding domain
LKMAKOFG_02824 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LKMAKOFG_02825 2.33e-190 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LKMAKOFG_02826 3.53e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
LKMAKOFG_02827 3.54e-117 batE - - T - - - Sh3 type 3 domain protein
LKMAKOFG_02828 4.01e-207 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LKMAKOFG_02829 1.54e-204 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LKMAKOFG_02830 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LKMAKOFG_02831 1.95e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LKMAKOFG_02832 2.94e-203 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LKMAKOFG_02833 4.28e-228 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
LKMAKOFG_02834 5.06e-260 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
LKMAKOFG_02835 1.03e-245 - - - E - - - Spore germination protein
LKMAKOFG_02836 4.41e-242 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
LKMAKOFG_02837 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
LKMAKOFG_02838 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
LKMAKOFG_02839 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LKMAKOFG_02840 4.04e-29 ywtC - - - - - - -
LKMAKOFG_02841 2.24e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LKMAKOFG_02842 5.17e-76 yttA - - S - - - Pfam Transposase IS66
LKMAKOFG_02843 3.72e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LKMAKOFG_02844 1.14e-229 ywtF_2 - - K - - - Transcriptional regulator
LKMAKOFG_02845 4.54e-316 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LKMAKOFG_02846 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
LKMAKOFG_02847 3e-272 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
LKMAKOFG_02848 2.88e-250 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LKMAKOFG_02849 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LKMAKOFG_02850 1.92e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LKMAKOFG_02851 5.05e-315 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LKMAKOFG_02852 2.49e-277 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKMAKOFG_02853 5.24e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LKMAKOFG_02854 2.69e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LKMAKOFG_02855 0.0 - - - M - - - Glycosyltransferase like family 2
LKMAKOFG_02856 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LKMAKOFG_02857 1.45e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LKMAKOFG_02858 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LKMAKOFG_02859 2.64e-211 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LKMAKOFG_02860 7.02e-268 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LKMAKOFG_02861 4.48e-204 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LKMAKOFG_02862 7.59e-64 - - - - - - - -
LKMAKOFG_02863 0.0 lytB - - D - - - Stage II sporulation protein
LKMAKOFG_02864 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LKMAKOFG_02865 1.22e-178 - - - M - - - cell wall anchor domain
LKMAKOFG_02866 9.14e-103 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LKMAKOFG_02867 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LKMAKOFG_02868 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LKMAKOFG_02869 2.39e-227 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
LKMAKOFG_02870 9.54e-286 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LKMAKOFG_02871 4.87e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKMAKOFG_02872 2.03e-277 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LKMAKOFG_02873 4.77e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LKMAKOFG_02874 1.02e-157 yflK - - S - - - protein conserved in bacteria
LKMAKOFG_02875 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
LKMAKOFG_02876 1.98e-26 yflI - - - - - - -
LKMAKOFG_02877 1.38e-65 yflH - - S - - - Protein of unknown function (DUF3243)
LKMAKOFG_02878 9.02e-176 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LKMAKOFG_02879 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LKMAKOFG_02880 4.56e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
LKMAKOFG_02881 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LKMAKOFG_02882 6.96e-83 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LKMAKOFG_02883 8.64e-106 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LKMAKOFG_02884 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
LKMAKOFG_02885 1.85e-53 ydgB - - S - - - Spore germination protein gerPA/gerPF
LKMAKOFG_02886 3.86e-314 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_02887 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LKMAKOFG_02888 2.89e-166 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LKMAKOFG_02889 2.93e-158 frp - - C - - - nitroreductase
LKMAKOFG_02890 8.16e-165 yibF - - S - - - YibE/F-like protein
LKMAKOFG_02891 3.4e-245 yibE - - S - - - YibE/F-like protein
LKMAKOFG_02892 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
LKMAKOFG_02893 7.82e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LKMAKOFG_02894 1.58e-239 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LKMAKOFG_02895 2.49e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LKMAKOFG_02896 1.95e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LKMAKOFG_02897 3.68e-247 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_02898 1.47e-41 yfkK - - S - - - Belongs to the UPF0435 family
LKMAKOFG_02899 4.84e-112 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKMAKOFG_02900 2.14e-69 yfkI - - S - - - gas vesicle protein
LKMAKOFG_02901 1.95e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LKMAKOFG_02902 6.71e-12 - - - - - - - -
LKMAKOFG_02903 6.59e-275 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_02904 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LKMAKOFG_02905 1.62e-185 yfkD - - S - - - YfkD-like protein
LKMAKOFG_02906 6.07e-188 yfkC - - M - - - Mechanosensitive ion channel
LKMAKOFG_02907 3.41e-281 yfkA - - S - - - YfkB-like domain
LKMAKOFG_02908 7.99e-37 yfjT - - - - - - -
LKMAKOFG_02909 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LKMAKOFG_02910 2.1e-188 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LKMAKOFG_02912 1.29e-235 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LKMAKOFG_02913 1.11e-204 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LKMAKOFG_02914 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKMAKOFG_02915 2.44e-244 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKMAKOFG_02916 5.07e-110 yfjM - - S - - - Psort location Cytoplasmic, score
LKMAKOFG_02917 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LKMAKOFG_02918 3.74e-242 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LKMAKOFG_02919 4.62e-273 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LKMAKOFG_02920 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LKMAKOFG_02921 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LKMAKOFG_02922 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
LKMAKOFG_02923 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LKMAKOFG_02924 2.21e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LKMAKOFG_02925 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_02926 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
LKMAKOFG_02927 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LKMAKOFG_02928 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LKMAKOFG_02929 5.54e-82 yfiD3 - - S - - - DoxX
LKMAKOFG_02930 1.16e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LKMAKOFG_02931 7.58e-217 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LKMAKOFG_02932 5.62e-126 padR - - K - - - transcriptional
LKMAKOFG_02933 1.79e-144 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
LKMAKOFG_02934 6.31e-235 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LKMAKOFG_02935 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
LKMAKOFG_02936 2.36e-60 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LKMAKOFG_02937 6.35e-126 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
LKMAKOFG_02938 0.0 yfiU - - EGP - - - the major facilitator superfamily
LKMAKOFG_02939 2.29e-107 yfiV - - K - - - transcriptional
LKMAKOFG_02940 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LKMAKOFG_02941 2e-206 yfhB - - S - - - PhzF family
LKMAKOFG_02942 9.61e-137 yfhC - - C - - - nitroreductase
LKMAKOFG_02943 3.61e-34 yfhD - - S - - - YfhD-like protein
LKMAKOFG_02945 1.48e-215 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
LKMAKOFG_02946 9e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LKMAKOFG_02947 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
LKMAKOFG_02948 2.86e-268 yfhI - - EGP - - - -transporter
LKMAKOFG_02950 5.78e-215 mpr - - M - - - Belongs to the peptidase S1B family
LKMAKOFG_02951 2.57e-59 yfhJ - - S - - - WVELL protein
LKMAKOFG_02952 2.32e-121 yfhK - - T - - - Bacterial SH3 domain homologues
LKMAKOFG_02953 4.24e-57 yfhL - - S - - - SdpI/YhfL protein family
LKMAKOFG_02954 1.6e-217 - - - S - - - Alpha/beta hydrolase family
LKMAKOFG_02955 1.57e-235 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LKMAKOFG_02956 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LKMAKOFG_02957 2.94e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LKMAKOFG_02958 9.18e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LKMAKOFG_02959 2.54e-50 yfhS - - - - - - -
LKMAKOFG_02960 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_02961 3.65e-07 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LKMAKOFG_02962 1.4e-49 ygaB - - S - - - YgaB-like protein
LKMAKOFG_02963 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LKMAKOFG_02964 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LKMAKOFG_02965 9.11e-240 ygaE - - S - - - Membrane
LKMAKOFG_02966 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LKMAKOFG_02967 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
LKMAKOFG_02968 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LKMAKOFG_02969 4.67e-75 ygzB - - S - - - UPF0295 protein
LKMAKOFG_02970 2.75e-213 ygxA - - S - - - Nucleotidyltransferase-like
LKMAKOFG_02971 2.17e-44 - - - S - - - amine dehydrogenase activity
LKMAKOFG_02973 8.92e-251 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LKMAKOFG_02974 7.54e-99 yoqH - - M - - - LysM domain
LKMAKOFG_02978 8.27e-20 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LKMAKOFG_02980 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LKMAKOFG_02981 1.51e-280 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
LKMAKOFG_02982 5.23e-230 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
LKMAKOFG_02983 3.12e-90 cgeA - - - ko:K06319 - ko00000 -
LKMAKOFG_02984 1.64e-62 cgeC - - - ko:K06321 - ko00000 -
LKMAKOFG_02985 1.97e-316 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
LKMAKOFG_02986 6.95e-186 yiiD - - K ko:K06323 - ko00000 acetyltransferase
LKMAKOFG_02988 3.97e-82 - - - L - - - Bacterial transcription activator, effector binding domain
LKMAKOFG_02989 4.84e-312 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKMAKOFG_02990 1.19e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LKMAKOFG_02991 7.69e-159 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LKMAKOFG_02992 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
LKMAKOFG_02993 1.4e-203 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
LKMAKOFG_02994 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
LKMAKOFG_02995 1.4e-62 yokU - - S - - - YokU-like protein, putative antitoxin
LKMAKOFG_02996 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
LKMAKOFG_02997 1.9e-161 yodN - - - - - - -
LKMAKOFG_02999 9.77e-34 yozD - - S - - - YozD-like protein
LKMAKOFG_03000 5.88e-131 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LKMAKOFG_03001 1.16e-72 yodL - - S - - - YodL-like
LKMAKOFG_03003 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LKMAKOFG_03004 1.5e-190 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LKMAKOFG_03005 6.87e-50 yodI - - - - - - -
LKMAKOFG_03006 6.12e-166 yodH - - Q - - - Methyltransferase
LKMAKOFG_03007 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LKMAKOFG_03008 3.53e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_03009 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LKMAKOFG_03010 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
LKMAKOFG_03011 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKMAKOFG_03012 1.62e-27 - - - S - - - Protein of unknown function (DUF3311)
LKMAKOFG_03013 4.43e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LKMAKOFG_03014 9.89e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
LKMAKOFG_03015 1.35e-138 yodC - - C - - - nitroreductase
LKMAKOFG_03016 1.2e-74 yodB - - K - - - transcriptional
LKMAKOFG_03017 9.21e-91 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
LKMAKOFG_03018 2.59e-89 iolK - - S - - - tautomerase
LKMAKOFG_03020 4.87e-106 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LKMAKOFG_03021 2.96e-210 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LKMAKOFG_03022 1.28e-31 - - - - - - - -
LKMAKOFG_03023 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
LKMAKOFG_03024 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
LKMAKOFG_03025 1.18e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKMAKOFG_03026 6.86e-310 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LKMAKOFG_03028 1.11e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKMAKOFG_03029 8.18e-286 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
LKMAKOFG_03030 1.41e-286 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LKMAKOFG_03031 6.26e-143 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LKMAKOFG_03032 4.2e-209 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
LKMAKOFG_03033 0.0 yojO - - P - - - Von Willebrand factor
LKMAKOFG_03034 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LKMAKOFG_03035 1.05e-262 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LKMAKOFG_03036 1.83e-179 - - - S - - - Metallo-beta-lactamase superfamily
LKMAKOFG_03037 2.82e-214 yocS - - S ko:K03453 - ko00000 -transporter
LKMAKOFG_03038 8.4e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LKMAKOFG_03039 8.22e-213 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
LKMAKOFG_03040 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LKMAKOFG_03041 8.13e-165 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKMAKOFG_03042 1.33e-183 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LKMAKOFG_03043 1.91e-42 yozC - - - - - - -
LKMAKOFG_03045 5.32e-75 yozO - - S - - - Bacterial PH domain
LKMAKOFG_03046 6.36e-50 yocN - - - - - - -
LKMAKOFG_03047 9.63e-60 yozN - - - - - - -
LKMAKOFG_03048 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LKMAKOFG_03049 3.51e-13 yocN - - - - - - -
LKMAKOFG_03050 1.92e-13 yocL - - - - - - -
LKMAKOFG_03051 1.06e-77 yocK - - T - - - general stress protein
LKMAKOFG_03053 8.11e-145 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LKMAKOFG_03054 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LKMAKOFG_03055 8.03e-167 yocH - - M - - - COG1388 FOG LysM repeat
LKMAKOFG_03057 1.92e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
LKMAKOFG_03058 2.27e-123 yocC - - - - - - -
LKMAKOFG_03059 3.38e-179 - - - J - - - Protein required for attachment to host cells
LKMAKOFG_03060 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
LKMAKOFG_03061 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LKMAKOFG_03062 6.33e-72 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
LKMAKOFG_03063 3.86e-119 yobW - - - - - - -
LKMAKOFG_03064 4e-174 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LKMAKOFG_03065 2.17e-121 yobS - - K - - - Transcriptional regulator
LKMAKOFG_03066 5.05e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
LKMAKOFG_03067 3.67e-71 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
LKMAKOFG_03068 2.02e-62 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LKMAKOFG_03069 6.17e-99 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LKMAKOFG_03070 3.31e-57 - - - - - - - -
LKMAKOFG_03071 1.56e-126 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_03073 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKMAKOFG_03074 7.32e-247 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LKMAKOFG_03075 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LKMAKOFG_03076 1.34e-262 yoaB - - EGP - - - the major facilitator superfamily
LKMAKOFG_03077 1.01e-174 yoxB - - - - - - -
LKMAKOFG_03078 2.6e-51 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LKMAKOFG_03079 1.73e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_03080 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LKMAKOFG_03081 3.42e-181 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LKMAKOFG_03082 4.87e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LKMAKOFG_03083 7.8e-207 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_03084 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LKMAKOFG_03085 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LKMAKOFG_03086 1.77e-239 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LKMAKOFG_03087 5.48e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_03088 3.44e-100 - - - CP - - - Membrane
LKMAKOFG_03090 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
LKMAKOFG_03091 2.41e-45 - - - - - - - -
LKMAKOFG_03092 1.18e-40 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
LKMAKOFG_03094 1.16e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LKMAKOFG_03095 6.08e-294 ywhK - - CO - - - amine dehydrogenase activity
LKMAKOFG_03096 8.63e-309 ywhL - - CO - - - amine dehydrogenase activity
LKMAKOFG_03098 2.21e-94 ywiB - - S - - - protein conserved in bacteria
LKMAKOFG_03099 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LKMAKOFG_03100 6.07e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LKMAKOFG_03101 1.33e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
LKMAKOFG_03102 2.81e-174 ywiC - - S - - - YwiC-like protein
LKMAKOFG_03103 2.05e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
LKMAKOFG_03104 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKMAKOFG_03105 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
LKMAKOFG_03106 2.67e-125 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
LKMAKOFG_03107 1.69e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
LKMAKOFG_03108 3.02e-136 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LKMAKOFG_03109 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LKMAKOFG_03110 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LKMAKOFG_03111 1.13e-58 ywjC - - - - - - -
LKMAKOFG_03112 3.03e-230 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LKMAKOFG_03113 1.72e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LKMAKOFG_03114 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LKMAKOFG_03115 1.78e-77 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LKMAKOFG_03116 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LKMAKOFG_03117 1.91e-119 ywjG - - S - - - Domain of unknown function (DUF2529)
LKMAKOFG_03118 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
LKMAKOFG_03119 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LKMAKOFG_03120 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LKMAKOFG_03121 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKMAKOFG_03122 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LKMAKOFG_03123 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LKMAKOFG_03124 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
LKMAKOFG_03125 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LKMAKOFG_03126 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LKMAKOFG_03127 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LKMAKOFG_03128 8.54e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LKMAKOFG_03129 6.14e-87 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKMAKOFG_03130 9.14e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LKMAKOFG_03131 9.87e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LKMAKOFG_03133 1.71e-78 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LKMAKOFG_03134 1.09e-151 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LKMAKOFG_03135 4.23e-99 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
LKMAKOFG_03136 1.53e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LKMAKOFG_03137 1.36e-118 mntP - - P - - - Probably functions as a manganese efflux pump
LKMAKOFG_03138 1.2e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LKMAKOFG_03139 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LKMAKOFG_03140 4.3e-124 ywlG - - S - - - Belongs to the UPF0340 family
LKMAKOFG_03141 1.99e-299 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LKMAKOFG_03142 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LKMAKOFG_03143 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
LKMAKOFG_03144 3e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LKMAKOFG_03145 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKMAKOFG_03146 2.36e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LKMAKOFG_03147 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LKMAKOFG_03148 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LKMAKOFG_03149 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LKMAKOFG_03150 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LKMAKOFG_03151 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LKMAKOFG_03152 4.15e-117 ywmA - - - - - - -
LKMAKOFG_03153 2.25e-45 ywzB - - S - - - membrane
LKMAKOFG_03154 8.35e-175 ywmB - - S - - - TATA-box binding
LKMAKOFG_03155 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LKMAKOFG_03156 5.64e-43 - - - - - - - -
LKMAKOFG_03157 1.13e-248 - 2.1.1.37 - NU ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
LKMAKOFG_03158 1.43e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LKMAKOFG_03160 2.88e-271 yycP - - - - - - -
LKMAKOFG_03161 7.96e-170 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LKMAKOFG_03162 6.14e-233 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LKMAKOFG_03163 5.66e-111 yycN - - K - - - Acetyltransferase
LKMAKOFG_03165 3.86e-261 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
LKMAKOFG_03166 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LKMAKOFG_03167 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKMAKOFG_03168 5e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LKMAKOFG_03169 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LKMAKOFG_03170 1.52e-187 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
LKMAKOFG_03171 0.0 - - - S - - - ABC transporter
LKMAKOFG_03172 5.06e-250 - - - S - - - Major Facilitator Superfamily
LKMAKOFG_03173 0.0 - - - - - - - -
LKMAKOFG_03174 1.56e-241 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
LKMAKOFG_03175 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LKMAKOFG_03176 2.5e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_03177 9.41e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LKMAKOFG_03178 5.69e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LKMAKOFG_03179 2.31e-193 yycI - - S - - - protein conserved in bacteria
LKMAKOFG_03180 0.0 yycH - - S - - - protein conserved in bacteria
LKMAKOFG_03181 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LKMAKOFG_03182 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_03187 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LKMAKOFG_03188 9.45e-96 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKMAKOFG_03189 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LKMAKOFG_03190 7.68e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LKMAKOFG_03192 7.28e-25 yycC - - K - - - YycC-like protein
LKMAKOFG_03193 8.16e-42 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase activity
LKMAKOFG_03194 6.82e-310 - - - M - - - Glycosyltransferase Family 4
LKMAKOFG_03195 3.16e-259 - - - S - - - Ecdysteroid kinase
LKMAKOFG_03196 2.09e-218 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
LKMAKOFG_03197 4.15e-65 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
LKMAKOFG_03198 0.0 - - - M - - - Glycosyltransferase Family 4
LKMAKOFG_03199 2.62e-158 - - - S - - - GlcNAc-PI de-N-acetylase
LKMAKOFG_03200 3.66e-134 - - - KLT - - - COG0515 Serine threonine protein kinase
LKMAKOFG_03201 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LKMAKOFG_03202 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LKMAKOFG_03203 1.53e-198 yybS - - S - - - membrane
LKMAKOFG_03205 3.33e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
LKMAKOFG_03206 4.56e-87 yybR - - K - - - Transcriptional regulator
LKMAKOFG_03207 2.95e-211 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LKMAKOFG_03208 2.39e-196 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LKMAKOFG_03209 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
LKMAKOFG_03210 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LKMAKOFG_03211 3.82e-149 - - - K - - - FCD domain
LKMAKOFG_03212 3.2e-116 - - - S - - - PFAM DinB family protein
LKMAKOFG_03213 2.72e-203 - - - G - - - Major Facilitator Superfamily
LKMAKOFG_03215 2.44e-72 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
LKMAKOFG_03216 1.7e-148 ydgI - - C - - - nitroreductase
LKMAKOFG_03217 3.36e-90 - - - K - - - Winged helix DNA-binding domain
LKMAKOFG_03218 2.99e-191 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LKMAKOFG_03219 1.3e-99 yybA - - K - - - transcriptional
LKMAKOFG_03220 2.49e-74 yjcF - - S - - - Acetyltransferase (GNAT) domain
LKMAKOFG_03221 2.02e-212 - - - M - - - Domain of Unknown Function (DUF1259)
LKMAKOFG_03222 4.76e-87 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LKMAKOFG_03223 4.21e-212 - - - K - - - Transcriptional regulator
LKMAKOFG_03224 3.34e-176 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LKMAKOFG_03225 2.68e-123 - - - - - - - -
LKMAKOFG_03226 1.83e-182 pdaB - - G - - - Polysaccharide deacetylase
LKMAKOFG_03227 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LKMAKOFG_03228 1.95e-102 gerD - - - ko:K06294 - ko00000 -
LKMAKOFG_03229 2.21e-254 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LKMAKOFG_03230 2.31e-172 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LKMAKOFG_03231 2.65e-102 ybaK - - S - - - Protein of unknown function (DUF2521)
LKMAKOFG_03232 3.83e-109 yizA - - S - - - Damage-inducible protein DinB
LKMAKOFG_03233 8.73e-186 ybaJ - - Q - - - Methyltransferase domain
LKMAKOFG_03234 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LKMAKOFG_03235 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LKMAKOFG_03236 4.16e-180 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LKMAKOFG_03237 7.93e-178 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKMAKOFG_03238 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKMAKOFG_03239 2.51e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LKMAKOFG_03240 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LKMAKOFG_03241 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKMAKOFG_03242 4.61e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LKMAKOFG_03243 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LKMAKOFG_03244 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LKMAKOFG_03245 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LKMAKOFG_03246 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LKMAKOFG_03247 3.82e-132 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LKMAKOFG_03248 1.34e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LKMAKOFG_03249 2.1e-94 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LKMAKOFG_03250 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LKMAKOFG_03251 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LKMAKOFG_03252 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LKMAKOFG_03253 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LKMAKOFG_03254 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LKMAKOFG_03255 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LKMAKOFG_03256 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LKMAKOFG_03257 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LKMAKOFG_03258 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LKMAKOFG_03259 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LKMAKOFG_03260 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LKMAKOFG_03261 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LKMAKOFG_03262 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LKMAKOFG_03263 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LKMAKOFG_03264 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LKMAKOFG_03265 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LKMAKOFG_03266 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LKMAKOFG_03267 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LKMAKOFG_03268 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LKMAKOFG_03269 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LKMAKOFG_03270 2.73e-238 ybaC - - S - - - Alpha/beta hydrolase family
LKMAKOFG_03271 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LKMAKOFG_03272 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LKMAKOFG_03273 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LKMAKOFG_03274 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LKMAKOFG_03275 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LKMAKOFG_03276 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKMAKOFG_03277 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LKMAKOFG_03278 4.9e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LKMAKOFG_03279 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LKMAKOFG_03280 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LKMAKOFG_03281 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LKMAKOFG_03282 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LKMAKOFG_03283 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LKMAKOFG_03284 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LKMAKOFG_03285 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LKMAKOFG_03286 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LKMAKOFG_03287 5.84e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LKMAKOFG_03288 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LKMAKOFG_03289 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LKMAKOFG_03290 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LKMAKOFG_03291 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LKMAKOFG_03292 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LKMAKOFG_03293 1.44e-159 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LKMAKOFG_03294 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LKMAKOFG_03295 7.66e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LKMAKOFG_03296 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LKMAKOFG_03297 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LKMAKOFG_03298 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LKMAKOFG_03299 9.39e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LKMAKOFG_03300 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LKMAKOFG_03301 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LKMAKOFG_03302 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LKMAKOFG_03303 8.67e-40 yazB - - K - - - transcriptional
LKMAKOFG_03304 2.35e-117 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LKMAKOFG_03305 4.62e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LKMAKOFG_03306 9.13e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LKMAKOFG_03307 1.91e-204 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
LKMAKOFG_03308 3.1e-138 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
LKMAKOFG_03309 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LKMAKOFG_03310 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LKMAKOFG_03311 1.19e-199 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
LKMAKOFG_03312 1.85e-205 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LKMAKOFG_03313 6.64e-187 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LKMAKOFG_03314 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LKMAKOFG_03315 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LKMAKOFG_03316 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LKMAKOFG_03317 3.3e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LKMAKOFG_03318 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LKMAKOFG_03319 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LKMAKOFG_03322 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LKMAKOFG_03323 2.42e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LKMAKOFG_03324 9.26e-132 yabQ - - S - - - spore cortex biosynthesis protein
LKMAKOFG_03325 5.47e-66 yabP - - S - - - Sporulation protein YabP
LKMAKOFG_03326 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LKMAKOFG_03327 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LKMAKOFG_03328 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LKMAKOFG_03329 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LKMAKOFG_03330 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LKMAKOFG_03331 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
LKMAKOFG_03332 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LKMAKOFG_03333 3.57e-136 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LKMAKOFG_03334 2.88e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LKMAKOFG_03335 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LKMAKOFG_03336 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LKMAKOFG_03337 1.24e-81 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LKMAKOFG_03338 5.67e-197 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LKMAKOFG_03339 2.73e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LKMAKOFG_03340 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
LKMAKOFG_03341 3.08e-52 veg - - S - - - protein conserved in bacteria
LKMAKOFG_03342 5.75e-209 yabG - - S ko:K06436 - ko00000 peptidase
LKMAKOFG_03343 2.07e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LKMAKOFG_03344 2.55e-124 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LKMAKOFG_03345 2.49e-310 yabE - - T - - - protein conserved in bacteria
LKMAKOFG_03346 1.5e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LKMAKOFG_03347 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LKMAKOFG_03348 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LKMAKOFG_03349 2.85e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LKMAKOFG_03350 5.73e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LKMAKOFG_03351 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LKMAKOFG_03352 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
LKMAKOFG_03353 9e-189 yaaT - - S - - - stage 0 sporulation protein
LKMAKOFG_03354 4.41e-228 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LKMAKOFG_03355 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LKMAKOFG_03356 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
LKMAKOFG_03357 1.9e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LKMAKOFG_03358 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LKMAKOFG_03359 9.43e-242 yaaN - - P - - - Belongs to the TelA family
LKMAKOFG_03360 3.42e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LKMAKOFG_03361 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
LKMAKOFG_03362 5.77e-56 - - - - - - - -
LKMAKOFG_03363 1.42e-07 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LKMAKOFG_03364 6.15e-185 yoaP - - K - - - YoaP-like
LKMAKOFG_03365 1.9e-127 - - - J - - - Acetyltransferase (GNAT) domain
LKMAKOFG_03366 5.31e-149 - - - S - - - Domain of unknown function (DUF3885)
LKMAKOFG_03367 6.88e-257 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LKMAKOFG_03368 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
LKMAKOFG_03369 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LKMAKOFG_03370 9.06e-125 yvgO - - - - - - -
LKMAKOFG_03372 0.0 yobO - - M - - - Pectate lyase superfamily protein
LKMAKOFG_03373 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LKMAKOFG_03374 1.37e-182 yndL - - S - - - Replication protein
LKMAKOFG_03375 1.74e-11 - - - - - - - -
LKMAKOFG_03376 1.04e-183 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
LKMAKOFG_03377 3.2e-95 yndM - - S - - - Protein of unknown function (DUF2512)
LKMAKOFG_03379 7.8e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LKMAKOFG_03380 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LKMAKOFG_03381 2.12e-144 yneB - - L - - - resolvase
LKMAKOFG_03382 2.33e-43 ynzC - - S - - - UPF0291 protein
LKMAKOFG_03383 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LKMAKOFG_03384 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LKMAKOFG_03385 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LKMAKOFG_03386 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
LKMAKOFG_03387 3.14e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LKMAKOFG_03388 2.47e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LKMAKOFG_03389 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LKMAKOFG_03390 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
LKMAKOFG_03391 2.44e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
LKMAKOFG_03392 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LKMAKOFG_03393 1.47e-20 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LKMAKOFG_03394 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LKMAKOFG_03395 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LKMAKOFG_03397 1.48e-45 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LKMAKOFG_03398 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LKMAKOFG_03399 4.68e-71 yneQ - - - - - - -
LKMAKOFG_03400 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
LKMAKOFG_03401 5.25e-120 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LKMAKOFG_03402 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LKMAKOFG_03403 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKMAKOFG_03404 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LKMAKOFG_03405 5.42e-20 - - - - - - - -
LKMAKOFG_03406 1.82e-63 ynfC - - - - - - -
LKMAKOFG_03407 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LKMAKOFG_03408 1.29e-230 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LKMAKOFG_03409 8.49e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
LKMAKOFG_03410 7.48e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LKMAKOFG_03411 4.62e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
LKMAKOFG_03412 2.13e-193 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LKMAKOFG_03413 1.75e-231 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
LKMAKOFG_03414 3.26e-108 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
LKMAKOFG_03415 5.67e-136 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
LKMAKOFG_03416 1.11e-196 yndG - - S - - - DoxX-like family
LKMAKOFG_03417 7.04e-84 - - - S - - - Domain of unknown function (DUF4166)
LKMAKOFG_03418 0.0 yndJ - - S - - - YndJ-like protein
LKMAKOFG_03419 1.17e-15 yxlH - - EGP - - - Major Facilitator Superfamily
LKMAKOFG_03422 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LKMAKOFG_03423 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
LKMAKOFG_03424 1.89e-275 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LKMAKOFG_03425 4.62e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
LKMAKOFG_03426 8.34e-197 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LKMAKOFG_03427 1.24e-314 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LKMAKOFG_03428 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LKMAKOFG_03429 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
LKMAKOFG_03431 5.53e-192 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
LKMAKOFG_03432 1.6e-82 ydjM - - M - - - Lytic transglycolase
LKMAKOFG_03433 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LKMAKOFG_03434 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKMAKOFG_03435 9.73e-194 rsiV - - S - - - Protein of unknown function (DUF3298)
LKMAKOFG_03436 0.0 oatA - - I - - - Acyltransferase family
LKMAKOFG_03437 4.01e-217 ydjI - - S - - - virion core protein (lumpy skin disease virus)
LKMAKOFG_03438 2.73e-163 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
LKMAKOFG_03439 8.57e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LKMAKOFG_03440 1.17e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
LKMAKOFG_03441 1.79e-41 yjdJ - - S - - - Domain of unknown function (DUF4306)
LKMAKOFG_03442 6.03e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LKMAKOFG_03443 2.72e-316 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LKMAKOFG_03444 3.55e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LKMAKOFG_03445 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LKMAKOFG_03446 1.45e-99 yfiJ - - T - - - helix_turn_helix, Lux Regulon
LKMAKOFG_03447 0.0 pbpX - - V - - - Beta-lactamase
LKMAKOFG_03448 2.24e-127 - - - S - - - Putative sensor
LKMAKOFG_03449 0.0 yvfT - - T - - - helix_turn_helix, Lux Regulon
LKMAKOFG_03450 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LKMAKOFG_03451 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LKMAKOFG_03452 8.26e-165 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LKMAKOFG_03453 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
LKMAKOFG_03454 1.92e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LKMAKOFG_03455 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LKMAKOFG_03456 1.29e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LKMAKOFG_03457 1.71e-116 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LKMAKOFG_03458 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LKMAKOFG_03459 9.22e-245 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LKMAKOFG_03460 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LKMAKOFG_03461 4.14e-162 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LKMAKOFG_03462 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LKMAKOFG_03463 1.39e-233 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LKMAKOFG_03468 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LKMAKOFG_03469 1.53e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LKMAKOFG_03470 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
LKMAKOFG_03471 7.35e-32 - - - S - - - Protein of unknown function (DUF3212)
LKMAKOFG_03472 1.35e-238 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LKMAKOFG_03473 7.08e-27 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LKMAKOFG_03474 4.93e-46 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
LKMAKOFG_03475 3.59e-264 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LKMAKOFG_03476 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKMAKOFG_03477 5.93e-263 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
LKMAKOFG_03478 2.05e-89 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
LKMAKOFG_03479 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LKMAKOFG_03480 1.2e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LKMAKOFG_03481 2.1e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LKMAKOFG_03482 2.85e-169 yfmS - - NT - - - chemotaxis protein
LKMAKOFG_03483 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LKMAKOFG_03484 9.36e-310 yfnA - - E ko:K03294 - ko00000 amino acid
LKMAKOFG_03485 3.67e-276 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LKMAKOFG_03486 8.13e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
LKMAKOFG_03487 1.46e-284 yfnE - - S - - - Glycosyltransferase like family 2
LKMAKOFG_03488 9.39e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
LKMAKOFG_03489 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
LKMAKOFG_03490 5.93e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
LKMAKOFG_03491 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LKMAKOFG_03492 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LKMAKOFG_03493 1.38e-251 yetN - - S - - - Protein of unknown function (DUF3900)
LKMAKOFG_03494 2.1e-265 yetM - - CH - - - FAD binding domain
LKMAKOFG_03495 3.45e-116 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_03496 2.19e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LKMAKOFG_03497 1.82e-73 - - - H - - - riboflavin kinase activity
LKMAKOFG_03498 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
LKMAKOFG_03499 7.64e-198 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LKMAKOFG_03500 3.78e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKMAKOFG_03501 4.52e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
LKMAKOFG_03502 7.39e-156 yetF - - S - - - membrane
LKMAKOFG_03503 5.92e-05 - - - - - - - -
LKMAKOFG_03504 1.39e-123 yesJ - - K - - - Acetyltransferase (GNAT) family
LKMAKOFG_03505 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
LKMAKOFG_03506 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
LKMAKOFG_03507 2.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LKMAKOFG_03509 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
LKMAKOFG_03510 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
LKMAKOFG_03511 1.63e-69 - - - S - - - Protein of unknown function, DUF600
LKMAKOFG_03512 4.36e-35 - - - S - - - Colicin immunity protein / pyocin immunity protein
LKMAKOFG_03513 7.68e-59 - - - S - - - ABC-2 family transporter protein
LKMAKOFG_03514 1.73e-68 - - - S - - - ABC-2 family transporter protein
LKMAKOFG_03515 2.99e-40 - - - - - - - -
LKMAKOFG_03516 2.64e-28 - - - - - - - -
LKMAKOFG_03517 1.29e-46 - - - S - - - Putative adhesin
LKMAKOFG_03518 1.16e-96 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_03519 9.97e-55 - - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LKMAKOFG_03520 1.44e-203 - - - T - - - Histidine kinase
LKMAKOFG_03521 2.12e-312 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LKMAKOFG_03522 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LKMAKOFG_03523 0.0 rocB - - E - - - arginine degradation protein
LKMAKOFG_03524 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LKMAKOFG_03525 1.28e-260 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LKMAKOFG_03526 1.36e-284 ywfA - - EGP - - - -transporter
LKMAKOFG_03527 1.15e-145 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LKMAKOFG_03528 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LKMAKOFG_03529 3.67e-177 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LKMAKOFG_03530 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LKMAKOFG_03531 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
LKMAKOFG_03532 3.82e-298 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
LKMAKOFG_03533 2.81e-179 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
LKMAKOFG_03534 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LKMAKOFG_03535 2.03e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LKMAKOFG_03536 6.6e-211 - - - S - - - Conserved hypothetical protein 698
LKMAKOFG_03537 2.25e-210 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LKMAKOFG_03538 7.2e-201 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LKMAKOFG_03540 1.29e-235 - - - - - - - -
LKMAKOFG_03543 1.79e-216 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
LKMAKOFG_03544 1.16e-211 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LKMAKOFG_03545 1.54e-119 - - - S - - - membrane
LKMAKOFG_03546 1.08e-67 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
LKMAKOFG_03547 5e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
LKMAKOFG_03548 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
LKMAKOFG_03549 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LKMAKOFG_03550 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
LKMAKOFG_03551 3.98e-315 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
LKMAKOFG_03552 4.16e-93 ywhA - - K - - - Transcriptional regulator
LKMAKOFG_03553 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LKMAKOFG_03554 7.44e-151 ywhC - - S - - - Peptidase family M50
LKMAKOFG_03555 1.92e-123 ywhD - - S - - - YwhD family
LKMAKOFG_03556 1.42e-74 - - - - - - - -
LKMAKOFG_03557 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LKMAKOFG_03558 1.58e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LKMAKOFG_03559 8.56e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LKMAKOFG_03561 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKMAKOFG_03562 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LKMAKOFG_03563 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
LKMAKOFG_03564 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LKMAKOFG_03565 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LKMAKOFG_03566 8.47e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LKMAKOFG_03567 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LKMAKOFG_03568 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LKMAKOFG_03569 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LKMAKOFG_03570 7.7e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LKMAKOFG_03571 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LKMAKOFG_03572 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LKMAKOFG_03573 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LKMAKOFG_03574 1.1e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LKMAKOFG_03575 1.23e-172 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LKMAKOFG_03576 5.82e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LKMAKOFG_03577 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
LKMAKOFG_03578 3.72e-105 yhhY - - K - - - FR47-like protein
LKMAKOFG_03579 1.67e-225 yyaD - - S - - - Membrane
LKMAKOFG_03580 1.82e-45 yyzM - - S - - - protein conserved in bacteria
LKMAKOFG_03581 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LKMAKOFG_03582 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LKMAKOFG_03583 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LKMAKOFG_03584 1.37e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LKMAKOFG_03585 4.51e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LKMAKOFG_03586 4.23e-135 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
LKMAKOFG_03587 4.28e-131 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LKMAKOFG_03588 1.4e-185 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LKMAKOFG_03589 9.8e-232 ccpB - - K - - - Transcriptional regulator
LKMAKOFG_03590 4.88e-88 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LKMAKOFG_03591 0.0 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
LKMAKOFG_03592 2e-208 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
LKMAKOFG_03593 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LKMAKOFG_03594 4.24e-168 - - - EG - - - EamA-like transporter family
LKMAKOFG_03595 4.31e-316 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LKMAKOFG_03596 2.2e-84 - - - O - - - Subtilase family
LKMAKOFG_03598 1.9e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKMAKOFG_03599 1.24e-312 - - - S - - - Domain of unknown function (DUF4179)
LKMAKOFG_03600 1.75e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LKMAKOFG_03601 2.52e-167 yebC - - M - - - Membrane
LKMAKOFG_03603 2.66e-120 yebE - - S - - - UPF0316 protein
LKMAKOFG_03604 2.21e-38 yebG - - S - - - NETI protein
LKMAKOFG_03605 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LKMAKOFG_03606 1.31e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LKMAKOFG_03607 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LKMAKOFG_03608 5.02e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LKMAKOFG_03609 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKMAKOFG_03610 3.17e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKMAKOFG_03611 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LKMAKOFG_03612 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LKMAKOFG_03613 4.38e-243 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LKMAKOFG_03614 4.22e-136 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LKMAKOFG_03615 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LKMAKOFG_03616 6.64e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LKMAKOFG_03617 3.21e-78 - - - K - - - helix_turn_helix ASNC type
LKMAKOFG_03618 2.76e-204 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
LKMAKOFG_03619 4.18e-34 - - - S - - - Protein of unknown function (DUF2892)
LKMAKOFG_03620 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LKMAKOFG_03621 5.77e-245 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LKMAKOFG_03622 8.28e-67 yerC - - S - - - protein conserved in bacteria
LKMAKOFG_03623 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LKMAKOFG_03624 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LKMAKOFG_03625 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LKMAKOFG_03626 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LKMAKOFG_03627 5.54e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LKMAKOFG_03628 2.55e-248 yerI - - S - - - homoserine kinase type II (protein kinase fold)
LKMAKOFG_03629 5.49e-282 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LKMAKOFG_03630 5.18e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LKMAKOFG_03631 2.7e-231 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
LKMAKOFG_03632 2.8e-256 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LKMAKOFG_03633 1.93e-288 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LKMAKOFG_03634 1.87e-223 ybaS - - S - - - Na -dependent transporter
LKMAKOFG_03635 2.61e-141 ybbA - - S ko:K07017 - ko00000 Putative esterase
LKMAKOFG_03636 2.04e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_03637 1.8e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LKMAKOFG_03638 1.93e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
LKMAKOFG_03639 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
LKMAKOFG_03640 7.8e-301 ybbC - - S - - - protein conserved in bacteria
LKMAKOFG_03641 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LKMAKOFG_03642 3.12e-309 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
LKMAKOFG_03643 1.24e-311 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LKMAKOFG_03644 4.48e-206 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LKMAKOFG_03645 5.87e-109 ybbJ - - J - - - acetyltransferase
LKMAKOFG_03646 6.45e-100 ybbK - - S - - - Protein of unknown function (DUF523)
LKMAKOFG_03652 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LKMAKOFG_03653 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LKMAKOFG_03654 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LKMAKOFG_03655 2.15e-292 ybbR - - S - - - protein conserved in bacteria
LKMAKOFG_03656 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LKMAKOFG_03657 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LKMAKOFG_03659 4.33e-27 - - - - - - - -
LKMAKOFG_03660 2.09e-95 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LKMAKOFG_03661 8.21e-97 xkdM - - S - - - Phage tail tube protein
LKMAKOFG_03662 8.06e-288 xkdK - - S - - - Phage tail sheath C-terminal domain
LKMAKOFG_03663 1.57e-20 - - - - - - - -
LKMAKOFG_03664 1.05e-74 xkdJ - - - - - - -
LKMAKOFG_03665 1.39e-76 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
LKMAKOFG_03666 9.99e-57 - - - S - - - Domain of unknown function (DUF3599)
LKMAKOFG_03667 2.53e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
LKMAKOFG_03668 8.3e-203 xkdG - - S - - - Phage capsid family
LKMAKOFG_03669 8.8e-119 xkdF3 - - L - - - Putative phage serine protease XkdF
LKMAKOFG_03670 4.24e-303 xkdE3 - - S - - - portal protein
LKMAKOFG_03671 5.54e-262 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
LKMAKOFG_03672 2.04e-141 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
LKMAKOFG_03673 3.57e-109 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LKMAKOFG_03677 2.32e-150 xkdC - - L - - - Bacterial dnaA protein
LKMAKOFG_03678 1.2e-142 xkdB - - K - - - sequence-specific DNA binding
LKMAKOFG_03680 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
LKMAKOFG_03681 1.54e-143 xkdA - - E - - - IrrE N-terminal-like domain
LKMAKOFG_03682 1.85e-142 yjqB - - S - - - phage-related replication protein
LKMAKOFG_03683 9.51e-81 yjqA - - S - - - Bacterial PH domain
LKMAKOFG_03684 6.78e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LKMAKOFG_03686 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LKMAKOFG_03687 8.38e-103 yjoA - - S - - - DinB family
LKMAKOFG_03688 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
LKMAKOFG_03689 9.29e-70 lcnDR2 - - V - - - Domain of unknown function (DUF4135)
LKMAKOFG_03690 2.19e-252 - - - S - - - Protein of unknown function (DUF1524)
LKMAKOFG_03691 5.75e-106 - - - S - - - Protein of unknown function (DUF1524)
LKMAKOFG_03692 1.35e-108 - 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (Adenine-specific)
LKMAKOFG_03693 1.94e-271 - - - S - - - Domain of unknown function DUF87
LKMAKOFG_03694 2.57e-169 - - - S - - - NurA domain
LKMAKOFG_03695 7.75e-235 - - - S - - - Fusaric acid resistance protein-like
LKMAKOFG_03696 2.07e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LKMAKOFG_03697 1.85e-119 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
LKMAKOFG_03698 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LKMAKOFG_03699 1.15e-198 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LKMAKOFG_03700 4.92e-110 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LKMAKOFG_03701 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
LKMAKOFG_03702 3.04e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LKMAKOFG_03703 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LKMAKOFG_03704 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
LKMAKOFG_03705 1.72e-141 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LKMAKOFG_03706 9.8e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LKMAKOFG_03707 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LKMAKOFG_03708 2.48e-111 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LKMAKOFG_03709 1.44e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
LKMAKOFG_03710 3.53e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LKMAKOFG_03711 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LKMAKOFG_03712 1.77e-157 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LKMAKOFG_03714 5.67e-259 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LKMAKOFG_03715 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LKMAKOFG_03716 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LKMAKOFG_03717 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LKMAKOFG_03718 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LKMAKOFG_03719 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LKMAKOFG_03720 4.77e-233 yaaC - - S - - - YaaC-like Protein
LKMAKOFG_03721 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LKMAKOFG_03722 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKMAKOFG_03723 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LKMAKOFG_03724 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LKMAKOFG_03725 3.16e-197 yerO - - K - - - Transcriptional regulator
LKMAKOFG_03726 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LKMAKOFG_03727 5.16e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LKMAKOFG_03728 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LKMAKOFG_03729 1e-90 vraR - - KT ko:K07694,ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_03731 0.0 ybeC - - E - - - amino acid
LKMAKOFG_03732 7.84e-55 ybyB - - - - - - -
LKMAKOFG_03733 1.77e-144 yqeB - - - - - - -
LKMAKOFG_03734 2.48e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
LKMAKOFG_03735 6.08e-102 - - - S - - - Domain of unknown function (DUF4879)
LKMAKOFG_03736 1.22e-37 - - - T - - - COG4585 Signal transduction histidine kinase
LKMAKOFG_03737 5.32e-119 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LKMAKOFG_03738 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LKMAKOFG_03740 2.29e-92 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LKMAKOFG_03741 3.3e-66 - - - S ko:K06518 - ko00000,ko02000 LrgA family
LKMAKOFG_03742 3.49e-134 yxaC - - M - - - effector of murein hydrolase
LKMAKOFG_03743 3.46e-205 dkgB - - S - - - Aldo/keto reductase family
LKMAKOFG_03744 6.2e-133 - - - S - - - ABC-2 family transporter protein
LKMAKOFG_03745 2.14e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LKMAKOFG_03747 3.62e-63 - - - Q - - - calcium- and calmodulin-responsive adenylate cyclase activity
LKMAKOFG_03748 2.07e-93 M1-820 - - Q - - - Collagen triple helix repeat (20 copies)
LKMAKOFG_03749 0.0 ywpD - - T - - - Histidine kinase
LKMAKOFG_03750 1.01e-192 M1-574 - - T - - - Transcriptional regulatory protein, C terminal
LKMAKOFG_03754 8.44e-278 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
LKMAKOFG_03755 0.0 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
LKMAKOFG_03757 1.26e-75 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LKMAKOFG_03758 2.28e-118 - 1.1.1.100 - IQ ko:K00059,ko:K07535 ko00061,ko00333,ko00362,ko00780,ko01040,ko01100,ko01120,ko01130,ko01212,ko01220,map00061,map00333,map00362,map00780,map01040,map01100,map01120,map01130,map01212,map01220 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LKMAKOFG_03759 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LKMAKOFG_03760 6.78e-176 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
LKMAKOFG_03761 2.67e-31 - - - S - - - Protein of unknown function, DUF600
LKMAKOFG_03762 1.35e-97 - - - S - - - Protein of unknown function, DUF600
LKMAKOFG_03764 1.54e-45 - - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LKMAKOFG_03765 4.7e-82 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LKMAKOFG_03766 1.02e-245 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LKMAKOFG_03767 3.19e-145 - 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 3-oxoacyl-[acyl-carrier-protein] synthase activity
LKMAKOFG_03768 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)