Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HLHFFEPM_00001	5.51e-302	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HLHFFEPM_00002	8.51e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLHFFEPM_00003	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHFFEPM_00004	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHFFEPM_00005	1.06e-259	-	-	-	-	-	-	-	-
HLHFFEPM_00006	1.86e-142	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HLHFFEPM_00007	3.56e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLHFFEPM_00008	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLHFFEPM_00009	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLHFFEPM_00010	7.44e-82	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLHFFEPM_00011	9.65e-175	-	-	-	L	ko:K07487	-	ko00000	Transposase
HLHFFEPM_00012	1.92e-299	isp	-	-	L	-	-	-	Transposase
HLHFFEPM_00013	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HLHFFEPM_00014	7.75e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLHFFEPM_00015	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HLHFFEPM_00016	4.22e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLHFFEPM_00017	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLHFFEPM_00018	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLHFFEPM_00019	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLHFFEPM_00020	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLHFFEPM_00021	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLHFFEPM_00022	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HLHFFEPM_00023	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLHFFEPM_00024	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLHFFEPM_00025	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLHFFEPM_00026	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLHFFEPM_00027	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLHFFEPM_00028	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLHFFEPM_00029	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLHFFEPM_00030	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLHFFEPM_00031	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLHFFEPM_00032	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HLHFFEPM_00033	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLHFFEPM_00034	9.61e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLHFFEPM_00035	6.16e-159	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLHFFEPM_00036	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLHFFEPM_00037	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HLHFFEPM_00038	2.19e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLHFFEPM_00039	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLHFFEPM_00040	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLHFFEPM_00041	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HLHFFEPM_00042	2.96e-178	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHFFEPM_00043	3.8e-194	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHFFEPM_00044	2.89e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLHFFEPM_00045	3.54e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLHFFEPM_00046	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLHFFEPM_00047	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HLHFFEPM_00048	2.58e-179	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HLHFFEPM_00049	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HLHFFEPM_00050	2.75e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLHFFEPM_00051	4.55e-267	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLHFFEPM_00052	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HLHFFEPM_00053	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLHFFEPM_00054	4.51e-260	camS	-	-	S	-	-	-	sex pheromone
HLHFFEPM_00055	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLHFFEPM_00056	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLHFFEPM_00057	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLHFFEPM_00058	4.7e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HLHFFEPM_00059	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLHFFEPM_00060	1.87e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLHFFEPM_00061	8.37e-87	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLHFFEPM_00062	2.68e-162	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HLHFFEPM_00063	9.37e-163	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHFFEPM_00064	0.0	-	-	-	L	-	-	-	Recombinase
HLHFFEPM_00065	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HLHFFEPM_00066	1.03e-37	-	-	-	-	-	-	-	-
HLHFFEPM_00067	8.75e-184	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HLHFFEPM_00068	5.95e-92	-	-	-	S	-	-	-	Bacteriophage holin family
HLHFFEPM_00069	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
HLHFFEPM_00070	6.21e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLHFFEPM_00071	1.29e-281	-	-	-	S	-	-	-	Phage capsid family
HLHFFEPM_00072	9.4e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HLHFFEPM_00073	2.37e-310	-	-	-	S	-	-	-	Phage portal protein
HLHFFEPM_00074	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HLHFFEPM_00075	8.38e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
HLHFFEPM_00076	3.45e-145	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLHFFEPM_00077	9.68e-292	-	-	-	KL	-	-	-	DNA methylase
HLHFFEPM_00078	2.4e-130	-	-	-	-	-	-	-	-
HLHFFEPM_00079	1.76e-113	-	-	-	-	-	-	-	-
HLHFFEPM_00080	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HLHFFEPM_00081	7.47e-63	-	-	-	S	-	-	-	VRR_NUC
HLHFFEPM_00082	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HLHFFEPM_00083	1.06e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLHFFEPM_00084	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HLHFFEPM_00085	1.06e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HLHFFEPM_00086	2.98e-269	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HLHFFEPM_00087	1.69e-55	-	-	-	-	-	-	-	-
HLHFFEPM_00088	4.37e-39	-	-	-	-	-	-	-	-
HLHFFEPM_00089	1.63e-94	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HLHFFEPM_00091	4.2e-163	-	-	-	F	-	-	-	helicase superfamily c-terminal domain
HLHFFEPM_00092	1.86e-32	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HLHFFEPM_00093	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLHFFEPM_00094	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HLHFFEPM_00095	2.67e-170	-	-	-	D	-	-	-	transport
HLHFFEPM_00096	3.13e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLHFFEPM_00097	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HLHFFEPM_00098	3.86e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
HLHFFEPM_00099	3.58e-106	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HLHFFEPM_00100	1.76e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLHFFEPM_00101	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HLHFFEPM_00102	1.73e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HLHFFEPM_00103	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLHFFEPM_00104	1.95e-68	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HLHFFEPM_00105	2.32e-232	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLHFFEPM_00108	3.55e-154	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HLHFFEPM_00109	3.37e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HLHFFEPM_00110	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HLHFFEPM_00111	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HLHFFEPM_00112	4.6e-173	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_00113	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHFFEPM_00114	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HLHFFEPM_00115	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HLHFFEPM_00116	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLHFFEPM_00117	3.9e-116	-	-	-	-	-	-	-	-
HLHFFEPM_00118	8e-49	-	-	-	-	-	-	-	-
HLHFFEPM_00119	1.64e-13	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLHFFEPM_00120	1.24e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLHFFEPM_00121	3.76e-175	epsB	-	-	M	-	-	-	biosynthesis protein
HLHFFEPM_00122	4.11e-152	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HLHFFEPM_00123	4.08e-138	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HLHFFEPM_00124	2.76e-164	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HLHFFEPM_00125	2.44e-56	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HLHFFEPM_00126	1.16e-103	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLHFFEPM_00127	1.61e-40	-	-	-	-	-	-	-	-
HLHFFEPM_00128	5.27e-38	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
HLHFFEPM_00129	4.17e-53	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLHFFEPM_00130	7.55e-120	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLHFFEPM_00131	5.6e-46	-	-	-	S	-	-	-	Acyltransferase family
HLHFFEPM_00134	2.04e-39	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLHFFEPM_00135	2.82e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HLHFFEPM_00136	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
HLHFFEPM_00137	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HLHFFEPM_00138	3.61e-71	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_00139	2.99e-66	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_00140	1.21e-53	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLHFFEPM_00141	4.76e-270	-	-	-	M	-	-	-	Rib/alpha-like repeat
HLHFFEPM_00142	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HLHFFEPM_00143	2.81e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HLHFFEPM_00144	2.32e-55	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLHFFEPM_00151	2.46e-36	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
HLHFFEPM_00152	7.15e-38	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HLHFFEPM_00153	9.83e-36	-	-	-	-	-	-	-	-
HLHFFEPM_00156	9.31e-59	-	-	-	-	-	-	-	-
HLHFFEPM_00157	2.25e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLHFFEPM_00164	5.34e-108	lytE	-	-	M	-	-	-	Lysin motif
HLHFFEPM_00165	3.16e-190	-	-	-	S	-	-	-	Cof-like hydrolase
HLHFFEPM_00166	6.2e-103	-	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_00167	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HLHFFEPM_00168	3e-69	-	-	-	-	-	-	-	-
HLHFFEPM_00169	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLHFFEPM_00170	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLHFFEPM_00171	5.7e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HLHFFEPM_00172	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLHFFEPM_00173	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HLHFFEPM_00174	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLHFFEPM_00175	1.25e-211	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLHFFEPM_00176	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HLHFFEPM_00177	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLHFFEPM_00178	1.19e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HLHFFEPM_00179	2.63e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHFFEPM_00180	3.44e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HLHFFEPM_00181	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HLHFFEPM_00182	4.35e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLHFFEPM_00183	6.49e-135	-	-	-	-	-	-	-	-
HLHFFEPM_00184	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HLHFFEPM_00185	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLHFFEPM_00186	5.57e-167	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HLHFFEPM_00187	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLHFFEPM_00188	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLHFFEPM_00189	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLHFFEPM_00190	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLHFFEPM_00191	1.45e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLHFFEPM_00192	4.41e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HLHFFEPM_00193	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLHFFEPM_00195	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLHFFEPM_00196	4.97e-131	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_00197	1.83e-21	-	-	-	-	-	-	-	-
HLHFFEPM_00199	1.59e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HLHFFEPM_00200	9.5e-238	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HLHFFEPM_00201	1.63e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HLHFFEPM_00202	4.5e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HLHFFEPM_00203	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLHFFEPM_00204	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLHFFEPM_00205	1.03e-19	-	-	-	-	-	-	-	-
HLHFFEPM_00206	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HLHFFEPM_00207	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HLHFFEPM_00208	9.93e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HLHFFEPM_00209	4.9e-207	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HLHFFEPM_00210	1.75e-257	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HLHFFEPM_00211	1.37e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLHFFEPM_00212	3.22e-214	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HLHFFEPM_00213	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HLHFFEPM_00214	8.71e-176	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HLHFFEPM_00216	3.47e-196	-	-	-	-	-	-	-	-
HLHFFEPM_00217	1.29e-37	-	-	-	-	-	-	-	-
HLHFFEPM_00218	1.29e-194	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HLHFFEPM_00219	9.68e-159	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLHFFEPM_00220	1.95e-131	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HLHFFEPM_00221	1.5e-91	-	-	-	-	-	-	-	-
HLHFFEPM_00222	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HLHFFEPM_00223	4.61e-133	-	-	-	L	-	-	-	nuclease
HLHFFEPM_00224	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HLHFFEPM_00225	3.9e-266	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLHFFEPM_00226	1.97e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HLHFFEPM_00227	0.0	snf	-	-	KL	-	-	-	domain protein
HLHFFEPM_00228	2.08e-234	snf	-	-	KL	-	-	-	domain protein
HLHFFEPM_00230	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HLHFFEPM_00231	5.1e-89	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HLHFFEPM_00233	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HLHFFEPM_00234	3.78e-219	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HLHFFEPM_00235	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HLHFFEPM_00236	5.45e-31	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLHFFEPM_00237	1.94e-147	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HLHFFEPM_00238	3.25e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_00239	1.15e-93	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_00240	6.71e-61	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HLHFFEPM_00241	5.59e-20	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HLHFFEPM_00242	3.47e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HLHFFEPM_00243	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HLHFFEPM_00244	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLHFFEPM_00245	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HLHFFEPM_00246	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLHFFEPM_00247	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLHFFEPM_00248	8.89e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HLHFFEPM_00249	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLHFFEPM_00250	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLHFFEPM_00251	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HLHFFEPM_00252	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLHFFEPM_00253	3.86e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLHFFEPM_00254	1.09e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HLHFFEPM_00255	2.7e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLHFFEPM_00256	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLHFFEPM_00257	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLHFFEPM_00258	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HLHFFEPM_00259	1.34e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLHFFEPM_00260	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLHFFEPM_00261	4.43e-41	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLHFFEPM_00262	2.33e-60	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLHFFEPM_00263	1.73e-128	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HLHFFEPM_00264	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HLHFFEPM_00265	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HLHFFEPM_00266	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HLHFFEPM_00267	9.25e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_00268	7.71e-81	-	-	-	-	-	-	-	-
HLHFFEPM_00269	2.53e-208	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HLHFFEPM_00270	1.58e-157	-	-	-	S	-	-	-	Fic/DOC family
HLHFFEPM_00272	6.3e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HLHFFEPM_00273	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HLHFFEPM_00275	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HLHFFEPM_00276	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLHFFEPM_00277	1.09e-311	yycH	-	-	S	-	-	-	YycH protein
HLHFFEPM_00278	1.18e-191	yycI	-	-	S	-	-	-	YycH protein
HLHFFEPM_00279	1.46e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HLHFFEPM_00280	7.56e-286	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HLHFFEPM_00282	1.47e-110	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HLHFFEPM_00283	1e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HLHFFEPM_00284	4.36e-114	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLHFFEPM_00286	6.12e-123	-	-	-	S	-	-	-	reductase
HLHFFEPM_00287	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HLHFFEPM_00288	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HLHFFEPM_00289	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
HLHFFEPM_00290	2.13e-189	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLHFFEPM_00291	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HLHFFEPM_00292	1.36e-198	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLHFFEPM_00293	3.99e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HLHFFEPM_00294	5.34e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HLHFFEPM_00295	4.34e-66	-	-	-	-	-	-	-	-
HLHFFEPM_00296	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HLHFFEPM_00299	3.99e-68	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HLHFFEPM_00300	1.79e-111	-	-	-	K	-	-	-	FR47-like protein
HLHFFEPM_00301	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
HLHFFEPM_00302	3.47e-221	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHFFEPM_00303	1.13e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHFFEPM_00304	2.49e-43	-	-	-	-	-	-	-	-
HLHFFEPM_00305	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HLHFFEPM_00307	9.22e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HLHFFEPM_00308	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHFFEPM_00309	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HLHFFEPM_00310	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HLHFFEPM_00311	2.11e-221	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLHFFEPM_00312	2.57e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HLHFFEPM_00313	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLHFFEPM_00314	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HLHFFEPM_00315	1.02e-153	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HLHFFEPM_00316	2.83e-90	-	-	-	-	-	-	-	-
HLHFFEPM_00317	1.02e-111	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HLHFFEPM_00318	9.03e-153	dltr	-	-	K	-	-	-	response regulator
HLHFFEPM_00319	1.32e-288	sptS	-	-	T	-	-	-	Histidine kinase
HLHFFEPM_00320	7.12e-275	-	-	-	P	-	-	-	Voltage gated chloride channel
HLHFFEPM_00321	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HLHFFEPM_00322	1.45e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HLHFFEPM_00323	1.48e-214	-	-	-	C	-	-	-	Aldo keto reductase
HLHFFEPM_00324	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HLHFFEPM_00325	3.77e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HLHFFEPM_00326	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HLHFFEPM_00327	2.42e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLHFFEPM_00328	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLHFFEPM_00329	1.56e-117	-	-	-	-	-	-	-	-
HLHFFEPM_00330	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLHFFEPM_00332	1.11e-16	-	-	-	E	-	-	-	amino acid
HLHFFEPM_00333	2.53e-17	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HLHFFEPM_00334	1.04e-37	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HLHFFEPM_00335	4.05e-39	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HLHFFEPM_00336	8.53e-95	-	-	-	-	-	-	-	-
HLHFFEPM_00337	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HLHFFEPM_00338	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HLHFFEPM_00339	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HLHFFEPM_00340	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HLHFFEPM_00341	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLHFFEPM_00342	4.08e-107	-	-	-	-	-	-	-	-
HLHFFEPM_00343	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HLHFFEPM_00344	6.21e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLHFFEPM_00345	9.26e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLHFFEPM_00346	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLHFFEPM_00347	8.67e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLHFFEPM_00348	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLHFFEPM_00349	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HLHFFEPM_00350	4.14e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HLHFFEPM_00351	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
HLHFFEPM_00352	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLHFFEPM_00353	1.13e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLHFFEPM_00354	3.29e-146	-	-	-	S	-	-	-	(CBS) domain
HLHFFEPM_00355	3.27e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HLHFFEPM_00356	1.59e-308	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HLHFFEPM_00357	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HLHFFEPM_00358	5.31e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HLHFFEPM_00359	8.16e-265	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLHFFEPM_00360	8.96e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLHFFEPM_00361	4.54e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HLHFFEPM_00362	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLHFFEPM_00363	1.1e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HLHFFEPM_00364	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLHFFEPM_00365	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLHFFEPM_00366	2.36e-67	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLHFFEPM_00367	8.59e-130	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLHFFEPM_00368	9.06e-195	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLHFFEPM_00369	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLHFFEPM_00370	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLHFFEPM_00371	3.7e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HLHFFEPM_00372	9.94e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HLHFFEPM_00373	5.7e-114	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLHFFEPM_00374	1.84e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HLHFFEPM_00375	5.32e-208	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HLHFFEPM_00376	8.28e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLHFFEPM_00377	5.24e-192	-	-	-	G	-	-	-	Right handed beta helix region
HLHFFEPM_00378	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HLHFFEPM_00379	4.8e-159	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HLHFFEPM_00380	7.58e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLHFFEPM_00381	1.46e-299	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLHFFEPM_00382	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HLHFFEPM_00383	1.11e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLHFFEPM_00384	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLHFFEPM_00385	2.44e-84	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLHFFEPM_00386	3.15e-71	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HLHFFEPM_00387	4.49e-193	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HLHFFEPM_00388	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HLHFFEPM_00389	7.71e-189	yidA	-	-	S	-	-	-	hydrolase
HLHFFEPM_00390	1.19e-98	-	-	-	-	-	-	-	-
HLHFFEPM_00391	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLHFFEPM_00392	2.14e-312	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLHFFEPM_00393	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HLHFFEPM_00394	1.75e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HLHFFEPM_00395	1.98e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HLHFFEPM_00396	1.93e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HLHFFEPM_00397	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLHFFEPM_00398	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HLHFFEPM_00399	1.03e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLHFFEPM_00400	4.08e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLHFFEPM_00401	3.58e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HLHFFEPM_00402	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLHFFEPM_00403	2.25e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HLHFFEPM_00405	2.31e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HLHFFEPM_00406	1.05e-225	-	-	-	-	-	-	-	-
HLHFFEPM_00407	9.64e-289	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HLHFFEPM_00408	3.08e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLHFFEPM_00409	2.26e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLHFFEPM_00410	1.51e-232	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HLHFFEPM_00411	3.42e-28	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLHFFEPM_00412	8.23e-112	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HLHFFEPM_00414	1.96e-35	-	-	-	-	-	-	-	-
HLHFFEPM_00415	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HLHFFEPM_00416	7.36e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HLHFFEPM_00417	1.02e-103	-	-	-	F	-	-	-	NUDIX domain
HLHFFEPM_00418	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLHFFEPM_00419	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLHFFEPM_00420	1.23e-135	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLHFFEPM_00421	5.11e-208	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HLHFFEPM_00422	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLHFFEPM_00423	1.07e-204	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HLHFFEPM_00424	5.03e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLHFFEPM_00425	2.08e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLHFFEPM_00426	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HLHFFEPM_00427	4.73e-140	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HLHFFEPM_00428	7.3e-216	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HLHFFEPM_00429	1.83e-195	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HLHFFEPM_00430	5.85e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HLHFFEPM_00431	1.95e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLHFFEPM_00432	1.41e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLHFFEPM_00433	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_00434	5.76e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLHFFEPM_00435	7.47e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HLHFFEPM_00436	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLHFFEPM_00437	9.51e-317	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HLHFFEPM_00438	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HLHFFEPM_00439	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HLHFFEPM_00440	1.04e-69	-	-	-	M	-	-	-	Lysin motif
HLHFFEPM_00441	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HLHFFEPM_00442	1.43e-250	-	-	-	S	-	-	-	Helix-turn-helix domain
HLHFFEPM_00443	8.52e-130	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLHFFEPM_00444	3.01e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HLHFFEPM_00445	5.49e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLHFFEPM_00446	9.25e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLHFFEPM_00447	1.01e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLHFFEPM_00448	5.3e-208	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HLHFFEPM_00449	1.47e-212	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HLHFFEPM_00450	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HLHFFEPM_00451	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HLHFFEPM_00452	3.79e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HLHFFEPM_00453	2.61e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HLHFFEPM_00454	1.1e-193	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLHFFEPM_00455	1.27e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HLHFFEPM_00456	7.19e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHFFEPM_00457	1.03e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLHFFEPM_00458	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLHFFEPM_00459	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HLHFFEPM_00460	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HLHFFEPM_00461	1.02e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HLHFFEPM_00462	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLHFFEPM_00463	1.66e-77	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HLHFFEPM_00464	2.21e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLHFFEPM_00465	2.22e-231	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HLHFFEPM_00466	2.54e-219	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLHFFEPM_00467	3.65e-111	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HLHFFEPM_00468	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HLHFFEPM_00469	2.07e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLHFFEPM_00470	5.92e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HLHFFEPM_00471	1.35e-91	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HLHFFEPM_00472	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HLHFFEPM_00473	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLHFFEPM_00474	1.05e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_00475	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HLHFFEPM_00476	3.62e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HLHFFEPM_00477	7.65e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLHFFEPM_00478	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLHFFEPM_00479	1.94e-68	-	-	-	-	-	-	-	-
HLHFFEPM_00480	1.08e-161	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLHFFEPM_00481	1.89e-228	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HLHFFEPM_00482	3.36e-77	-	-	-	-	-	-	-	-
HLHFFEPM_00484	1.31e-219	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLHFFEPM_00486	2.49e-255	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HLHFFEPM_00487	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHFFEPM_00488	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLHFFEPM_00489	1.81e-272	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLHFFEPM_00490	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HLHFFEPM_00491	3.69e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLHFFEPM_00492	7.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLHFFEPM_00493	1.04e-83	-	-	-	-	-	-	-	-
HLHFFEPM_00494	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HLHFFEPM_00495	1.85e-210	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLHFFEPM_00496	2.79e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLHFFEPM_00497	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLHFFEPM_00498	7.97e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HLHFFEPM_00499	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HLHFFEPM_00500	1.18e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HLHFFEPM_00501	6.36e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HLHFFEPM_00502	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLHFFEPM_00503	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLHFFEPM_00504	8.1e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HLHFFEPM_00505	5.83e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HLHFFEPM_00506	1.29e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLHFFEPM_00507	3.48e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLHFFEPM_00508	1.72e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HLHFFEPM_00509	1.82e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLHFFEPM_00510	2.91e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HLHFFEPM_00511	4.65e-230	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHFFEPM_00512	9.65e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HLHFFEPM_00513	5.67e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HLHFFEPM_00514	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HLHFFEPM_00515	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HLHFFEPM_00516	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HLHFFEPM_00517	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLHFFEPM_00518	1.94e-268	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HLHFFEPM_00519	1.2e-162	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLHFFEPM_00520	1.11e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLHFFEPM_00521	6.95e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HLHFFEPM_00522	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLHFFEPM_00523	3.99e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HLHFFEPM_00524	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HLHFFEPM_00525	6.28e-19	-	-	-	-	-	-	-	-
HLHFFEPM_00526	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLHFFEPM_00527	8.66e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HLHFFEPM_00528	1.05e-45	-	-	-	-	-	-	-	-
HLHFFEPM_00529	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLHFFEPM_00530	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HLHFFEPM_00531	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HLHFFEPM_00532	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLHFFEPM_00533	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HLHFFEPM_00534	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HLHFFEPM_00535	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLHFFEPM_00536	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLHFFEPM_00537	3.16e-261	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLHFFEPM_00538	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HLHFFEPM_00539	6.38e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLHFFEPM_00540	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLHFFEPM_00541	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLHFFEPM_00542	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLHFFEPM_00543	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HLHFFEPM_00544	2.03e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HLHFFEPM_00545	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HLHFFEPM_00546	4.7e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HLHFFEPM_00547	1.06e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HLHFFEPM_00548	4.03e-207	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLHFFEPM_00549	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HLHFFEPM_00550	1.17e-165	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HLHFFEPM_00551	1.85e-316	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLHFFEPM_00552	7.08e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLHFFEPM_00553	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLHFFEPM_00554	3.56e-263	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLHFFEPM_00555	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLHFFEPM_00556	2.08e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HLHFFEPM_00557	8.66e-70	-	-	-	-	-	-	-	-
HLHFFEPM_00558	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HLHFFEPM_00559	1.07e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLHFFEPM_00560	2.81e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HLHFFEPM_00561	2.49e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HLHFFEPM_00562	1.15e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLHFFEPM_00563	3.95e-280	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLHFFEPM_00564	1.88e-191	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLHFFEPM_00565	1.84e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLHFFEPM_00566	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HLHFFEPM_00567	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HLHFFEPM_00568	4.3e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLHFFEPM_00569	7.44e-168	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLHFFEPM_00570	5.93e-60	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HLHFFEPM_00571	8.44e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HLHFFEPM_00572	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HLHFFEPM_00573	1.53e-52	-	-	-	-	-	-	-	-
HLHFFEPM_00574	0.0	ydaO	-	-	E	-	-	-	amino acid
HLHFFEPM_00575	0.0	-	-	-	E	-	-	-	amino acid
HLHFFEPM_00576	7.32e-105	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HLHFFEPM_00577	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLHFFEPM_00578	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLHFFEPM_00580	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLHFFEPM_00581	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HLHFFEPM_00582	6.07e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLHFFEPM_00583	6.54e-222	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLHFFEPM_00584	2.6e-33	-	-	-	-	-	-	-	-
HLHFFEPM_00585	8.12e-144	-	-	-	-	-	-	-	-
HLHFFEPM_00586	2.76e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_00587	3.24e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HLHFFEPM_00588	1.42e-112	-	-	-	-	-	-	-	-
HLHFFEPM_00589	2.49e-141	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HLHFFEPM_00590	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HLHFFEPM_00591	4.02e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HLHFFEPM_00593	1.46e-126	-	-	-	-	-	-	-	-
HLHFFEPM_00594	1.89e-275	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLHFFEPM_00595	4.79e-87	-	-	-	S	-	-	-	Alpha beta hydrolase
HLHFFEPM_00596	6.21e-82	-	-	-	S	-	-	-	Alpha beta hydrolase
HLHFFEPM_00597	8.15e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HLHFFEPM_00598	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLHFFEPM_00599	1.7e-54	-	-	-	-	-	-	-	-
HLHFFEPM_00600	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HLHFFEPM_00601	5.37e-45	-	-	-	K	-	-	-	Bacterial transcriptional regulator
HLHFFEPM_00602	7.63e-90	-	1.1.1.100, 1.1.1.304, 1.1.1.76	-	IQ	ko:K00059,ko:K18009	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HLHFFEPM_00603	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HLHFFEPM_00604	2.22e-312	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HLHFFEPM_00605	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HLHFFEPM_00606	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHFFEPM_00607	3.34e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HLHFFEPM_00608	2.09e-214	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HLHFFEPM_00609	1.08e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HLHFFEPM_00610	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLHFFEPM_00611	1.15e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HLHFFEPM_00612	1.33e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HLHFFEPM_00613	6.27e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
HLHFFEPM_00614	4.63e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_00615	3.37e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HLHFFEPM_00616	7.44e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HLHFFEPM_00617	4.41e-158	-	-	-	M	-	-	-	PFAM NLP P60 protein
HLHFFEPM_00618	5.85e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HLHFFEPM_00619	5.78e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HLHFFEPM_00620	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
HLHFFEPM_00622	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HLHFFEPM_00623	3.96e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HLHFFEPM_00625	3.65e-255	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HLHFFEPM_00629	1.44e-140	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLHFFEPM_00630	3.97e-107	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HLHFFEPM_00631	3.25e-72	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLHFFEPM_00632	4.8e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HLHFFEPM_00633	2.01e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLHFFEPM_00634	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HLHFFEPM_00635	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HLHFFEPM_00636	7.96e-158	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HLHFFEPM_00637	1.57e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HLHFFEPM_00638	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HLHFFEPM_00639	2.86e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HLHFFEPM_00640	8.5e-218	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HLHFFEPM_00641	3.24e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HLHFFEPM_00642	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLHFFEPM_00643	2.78e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HLHFFEPM_00644	1.42e-152	-	-	-	L	-	-	-	Transposase
HLHFFEPM_00645	8.71e-164	-	-	-	L	-	-	-	Transposase
HLHFFEPM_00646	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HLHFFEPM_00647	2.61e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HLHFFEPM_00648	1.73e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HLHFFEPM_00649	2.76e-151	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLHFFEPM_00650	1.22e-136	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HLHFFEPM_00651	2.85e-61	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HLHFFEPM_00652	6.29e-191	-	-	-	O	-	-	-	Band 7 protein
HLHFFEPM_00653	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HLHFFEPM_00654	3.3e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HLHFFEPM_00655	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
HLHFFEPM_00656	7.15e-148	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HLHFFEPM_00657	6.4e-204	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HLHFFEPM_00658	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLHFFEPM_00659	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HLHFFEPM_00660	1.24e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HLHFFEPM_00661	7.46e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLHFFEPM_00662	2.36e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HLHFFEPM_00663	1.56e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HLHFFEPM_00664	2.84e-42	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HLHFFEPM_00665	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HLHFFEPM_00666	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLHFFEPM_00667	1.16e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLHFFEPM_00668	9.92e-78	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HLHFFEPM_00669	5.37e-137	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HLHFFEPM_00670	6.65e-158	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HLHFFEPM_00671	8.19e-100	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HLHFFEPM_00672	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HLHFFEPM_00673	2.12e-145	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HLHFFEPM_00674	2.9e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HLHFFEPM_00676	5.19e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHFFEPM_00677	2.02e-306	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HLHFFEPM_00678	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HLHFFEPM_00679	2.19e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HLHFFEPM_00680	7.16e-201	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HLHFFEPM_00681	5.35e-86	-	-	-	M	-	-	-	LysM domain protein
HLHFFEPM_00682	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HLHFFEPM_00683	1.46e-134	-	-	-	M	-	-	-	LysM domain protein
HLHFFEPM_00684	5.48e-188	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HLHFFEPM_00685	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HLHFFEPM_00686	5.38e-308	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HLHFFEPM_00687	2.14e-195	yeaE	-	-	S	-	-	-	Aldo keto
HLHFFEPM_00688	1.55e-99	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HLHFFEPM_00689	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HLHFFEPM_00690	4.4e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HLHFFEPM_00691	1.36e-99	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HLHFFEPM_00692	7.03e-33	-	-	-	-	-	-	-	-
HLHFFEPM_00693	1.13e-132	-	-	-	V	-	-	-	VanZ like family
HLHFFEPM_00694	2.01e-302	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLHFFEPM_00695	1.46e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HLHFFEPM_00696	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_00697	7.72e-122	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HLHFFEPM_00698	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLHFFEPM_00699	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HLHFFEPM_00700	1.77e-56	-	-	-	-	-	-	-	-
HLHFFEPM_00701	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HLHFFEPM_00702	8.34e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLHFFEPM_00703	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HLHFFEPM_00704	2.18e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLHFFEPM_00705	4.49e-222	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLHFFEPM_00706	2.52e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HLHFFEPM_00707	1.53e-146	-	-	-	-	-	-	-	-
HLHFFEPM_00708	3.58e-238	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HLHFFEPM_00709	4.68e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLHFFEPM_00710	1.78e-42	-	-	-	-	-	-	-	-
HLHFFEPM_00711	1.48e-149	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLHFFEPM_00712	9.17e-59	-	-	-	-	-	-	-	-
HLHFFEPM_00714	4.27e-89	-	-	-	-	-	-	-	-
HLHFFEPM_00715	3.38e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLHFFEPM_00716	1.25e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HLHFFEPM_00717	7.92e-135	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HLHFFEPM_00718	2.14e-280	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLHFFEPM_00719	1.12e-131	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HLHFFEPM_00720	1.53e-266	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HLHFFEPM_00721	1.88e-60	-	-	-	-	-	-	-	-
HLHFFEPM_00722	2.47e-53	-	-	-	-	-	-	-	-
HLHFFEPM_00724	2.15e-210	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HLHFFEPM_00725	2.51e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLHFFEPM_00726	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HLHFFEPM_00727	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HLHFFEPM_00728	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HLHFFEPM_00729	2.34e-285	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HLHFFEPM_00730	0.0	yhaN	-	-	L	-	-	-	AAA domain
HLHFFEPM_00731	4.08e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLHFFEPM_00733	8.29e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HLHFFEPM_00734	5.44e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_00735	1.9e-278	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLHFFEPM_00736	2.9e-38	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLHFFEPM_00737	6.07e-90	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLHFFEPM_00738	4.37e-23	-	-	-	S	-	-	-	YSIRK type signal peptide
HLHFFEPM_00739	1.79e-18	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HLHFFEPM_00740	6.19e-16	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HLHFFEPM_00741	8.08e-76	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HLHFFEPM_00742	1.59e-14	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HLHFFEPM_00743	5.37e-74	-	-	-	S	-	-	-	Small secreted protein
HLHFFEPM_00744	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
HLHFFEPM_00745	1.99e-153	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLHFFEPM_00746	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HLHFFEPM_00747	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLHFFEPM_00748	2.26e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HLHFFEPM_00749	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLHFFEPM_00750	2.16e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLHFFEPM_00751	1.62e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLHFFEPM_00752	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLHFFEPM_00753	3.85e-298	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HLHFFEPM_00754	8.6e-222	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HLHFFEPM_00755	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLHFFEPM_00756	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HLHFFEPM_00757	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLHFFEPM_00759	2.8e-81	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HLHFFEPM_00762	8.76e-75	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
HLHFFEPM_00763	1.09e-26	-	-	-	S	-	-	-	exonuclease activity
HLHFFEPM_00766	8.58e-73	-	-	-	-	-	-	-	-
HLHFFEPM_00767	5.79e-88	-	-	-	-	-	-	-	-
HLHFFEPM_00775	5.17e-57	-	-	-	K	-	-	-	COG3617 Prophage antirepressor
HLHFFEPM_00777	4.38e-23	-	-	-	S	-	-	-	Helix-turn-helix domain
HLHFFEPM_00778	1.41e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HLHFFEPM_00779	9.62e-41	-	-	-	-	-	-	-	-
HLHFFEPM_00780	2.2e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HLHFFEPM_00781	1.6e-172	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLHFFEPM_00782	8.86e-122	-	-	-	-	-	-	-	-
HLHFFEPM_00783	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLHFFEPM_00784	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HLHFFEPM_00785	2.9e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HLHFFEPM_00786	2.79e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLHFFEPM_00787	9.78e-314	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLHFFEPM_00788	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLHFFEPM_00789	2.44e-20	-	-	-	-	-	-	-	-
HLHFFEPM_00790	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HLHFFEPM_00791	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HLHFFEPM_00792	4.15e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLHFFEPM_00793	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLHFFEPM_00794	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLHFFEPM_00795	3.07e-209	-	-	-	S	-	-	-	Tetratricopeptide repeat
HLHFFEPM_00796	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLHFFEPM_00797	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLHFFEPM_00798	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HLHFFEPM_00799	2.27e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HLHFFEPM_00800	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HLHFFEPM_00801	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HLHFFEPM_00802	4.83e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HLHFFEPM_00803	2.03e-250	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HLHFFEPM_00804	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLHFFEPM_00805	4.59e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HLHFFEPM_00806	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HLHFFEPM_00807	1.52e-283	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HLHFFEPM_00808	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HLHFFEPM_00809	4.59e-173	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HLHFFEPM_00810	1.32e-59	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HLHFFEPM_00811	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HLHFFEPM_00812	1.23e-310	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLHFFEPM_00813	1.34e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HLHFFEPM_00814	6.71e-265	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HLHFFEPM_00815	2.78e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLHFFEPM_00816	3.66e-103	-	-	-	-	-	-	-	-
HLHFFEPM_00817	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HLHFFEPM_00818	7.16e-231	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HLHFFEPM_00819	4.37e-39	-	-	-	-	-	-	-	-
HLHFFEPM_00820	2.51e-217	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HLHFFEPM_00822	2.15e-75	-	-	-	-	-	-	-	-
HLHFFEPM_00823	3.74e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HLHFFEPM_00824	1.1e-279	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HLHFFEPM_00825	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HLHFFEPM_00826	4.47e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLHFFEPM_00827	5.91e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHFFEPM_00828	1.56e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLHFFEPM_00829	1.32e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLHFFEPM_00830	2.32e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLHFFEPM_00831	4.39e-110	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLHFFEPM_00832	9.35e-311	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLHFFEPM_00833	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HLHFFEPM_00834	2.6e-233	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLHFFEPM_00835	3.49e-222	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLHFFEPM_00836	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLHFFEPM_00837	5.21e-155	-	-	-	S	-	-	-	repeat protein
HLHFFEPM_00838	5.71e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HLHFFEPM_00839	1.02e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLHFFEPM_00840	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HLHFFEPM_00841	1.1e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLHFFEPM_00842	6.59e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLHFFEPM_00843	1.19e-25	-	-	-	-	-	-	-	-
HLHFFEPM_00844	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HLHFFEPM_00845	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HLHFFEPM_00846	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLHFFEPM_00847	8.87e-101	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HLHFFEPM_00848	2.5e-188	ylmH	-	-	S	-	-	-	S4 domain protein
HLHFFEPM_00849	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HLHFFEPM_00850	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLHFFEPM_00851	8.44e-284	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLHFFEPM_00852	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLHFFEPM_00853	2.35e-183	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLHFFEPM_00854	1.98e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLHFFEPM_00855	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLHFFEPM_00856	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLHFFEPM_00857	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLHFFEPM_00858	9.94e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HLHFFEPM_00859	2.1e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLHFFEPM_00860	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HLHFFEPM_00861	6.9e-77	-	-	-	-	-	-	-	-
HLHFFEPM_00862	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HLHFFEPM_00863	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HLHFFEPM_00864	3.75e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLHFFEPM_00865	8.76e-201	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HLHFFEPM_00866	3.12e-250	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HLHFFEPM_00868	1.68e-187	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLHFFEPM_00869	2.96e-57	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLHFFEPM_00870	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HLHFFEPM_00871	6.92e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HLHFFEPM_00872	6.76e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLHFFEPM_00873	2.66e-120	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HLHFFEPM_00874	1.71e-143	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLHFFEPM_00875	4.36e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLHFFEPM_00876	4.01e-183	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HLHFFEPM_00878	6.3e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HLHFFEPM_00879	1.88e-53	-	-	-	-	-	-	-	-
HLHFFEPM_00880	1.18e-99	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HLHFFEPM_00881	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HLHFFEPM_00882	2.04e-231	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HLHFFEPM_00883	5.68e-233	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HLHFFEPM_00884	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HLHFFEPM_00885	6.09e-174	-	-	-	-	-	-	-	-
HLHFFEPM_00886	6.62e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HLHFFEPM_00887	1.21e-266	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HLHFFEPM_00888	2.04e-72	-	-	-	-	-	-	-	-
HLHFFEPM_00889	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLHFFEPM_00890	7.58e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HLHFFEPM_00891	3.3e-197	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HLHFFEPM_00892	1.69e-296	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HLHFFEPM_00893	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLHFFEPM_00894	3.46e-95	-	-	-	F	-	-	-	Nudix hydrolase
HLHFFEPM_00895	1.26e-130	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HLHFFEPM_00896	2.03e-105	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HLHFFEPM_00897	1.01e-29	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HLHFFEPM_00898	3.82e-192	-	-	-	-	-	-	-	-
HLHFFEPM_00899	1.23e-52	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HLHFFEPM_00900	1.44e-121	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HLHFFEPM_00901	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HLHFFEPM_00902	1.56e-229	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHFFEPM_00903	6.47e-10	-	-	-	S	-	-	-	CsbD-like
HLHFFEPM_00904	3.69e-45	-	-	-	S	-	-	-	Transglycosylase associated protein
HLHFFEPM_00905	7.69e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLHFFEPM_00906	6.69e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HLHFFEPM_00907	1.9e-147	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HLHFFEPM_00908	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HLHFFEPM_00909	3.89e-49	-	-	-	Q	-	-	-	pyridine nucleotide-disulphide oxidoreductase
HLHFFEPM_00910	3.42e-200	-	-	-	EG	-	-	-	EamA-like transporter family
HLHFFEPM_00911	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HLHFFEPM_00912	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HLHFFEPM_00913	5.67e-278	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HLHFFEPM_00915	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HLHFFEPM_00916	1.9e-21	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLHFFEPM_00917	7.67e-80	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLHFFEPM_00919	8.55e-99	ykuL	-	-	S	-	-	-	(CBS) domain
HLHFFEPM_00920	1.65e-120	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HLHFFEPM_00921	4.22e-136	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLHFFEPM_00922	6.89e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HLHFFEPM_00923	5.82e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HLHFFEPM_00924	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HLHFFEPM_00925	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLHFFEPM_00926	1.44e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
HLHFFEPM_00927	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HLHFFEPM_00928	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLHFFEPM_00929	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HLHFFEPM_00930	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLHFFEPM_00931	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLHFFEPM_00932	3.56e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HLHFFEPM_00933	1.44e-59	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HLHFFEPM_00934	9.79e-239	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLHFFEPM_00935	2.74e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLHFFEPM_00936	4.34e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLHFFEPM_00937	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLHFFEPM_00938	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLHFFEPM_00939	4.62e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HLHFFEPM_00940	2.2e-251	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLHFFEPM_00941	1.08e-287	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HLHFFEPM_00942	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLHFFEPM_00943	4.4e-192	-	-	-	S	-	-	-	Helix-turn-helix domain
HLHFFEPM_00944	1.92e-316	ymfH	-	-	S	-	-	-	Peptidase M16
HLHFFEPM_00945	1.87e-288	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HLHFFEPM_00946	3.32e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HLHFFEPM_00947	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_00948	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HLHFFEPM_00949	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HLHFFEPM_00950	3.82e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HLHFFEPM_00951	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HLHFFEPM_00952	4.2e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HLHFFEPM_00953	9.28e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HLHFFEPM_00954	1.81e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HLHFFEPM_00955	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HLHFFEPM_00956	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HLHFFEPM_00957	5.45e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HLHFFEPM_00958	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HLHFFEPM_00959	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLHFFEPM_00960	2.37e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLHFFEPM_00961	7.1e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HLHFFEPM_00962	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLHFFEPM_00963	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLHFFEPM_00964	3.01e-149	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_00965	9.42e-41	-	-	-	L	-	-	-	Helix-turn-helix domain
HLHFFEPM_00966	5.86e-157	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HLHFFEPM_00967	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLHFFEPM_00968	1.84e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLHFFEPM_00970	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HLHFFEPM_00971	1.26e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HLHFFEPM_00972	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLHFFEPM_00973	3.57e-238	-	-	-	-	-	-	-	-
HLHFFEPM_00974	1.58e-79	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLHFFEPM_00975	1.59e-87	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HLHFFEPM_00976	1.56e-41	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLHFFEPM_00977	2.76e-67	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HLHFFEPM_00978	1.91e-125	-	-	-	K	-	-	-	acetyltransferase
HLHFFEPM_00979	1.64e-238	-	-	-	-	-	-	-	-
HLHFFEPM_00981	2.58e-164	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HLHFFEPM_00982	1.99e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HLHFFEPM_00983	1.26e-191	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HLHFFEPM_00984	4.47e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HLHFFEPM_00985	9.02e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLHFFEPM_00986	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HLHFFEPM_00987	3.28e-197	-	-	-	-	-	-	-	-
HLHFFEPM_00988	1.2e-237	-	-	-	M	-	-	-	Glycosyl transferase
HLHFFEPM_00989	3.81e-52	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HLHFFEPM_00990	2.94e-285	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HLHFFEPM_00991	3.28e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HLHFFEPM_00992	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HLHFFEPM_00993	1.37e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HLHFFEPM_00994	4.64e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HLHFFEPM_00995	3.1e-113	-	-	-	Q	-	-	-	Methyltransferase
HLHFFEPM_00996	2.2e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLHFFEPM_00997	1.28e-226	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HLHFFEPM_00998	4.21e-213	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLHFFEPM_00999	8.7e-123	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HLHFFEPM_01000	4.8e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HLHFFEPM_01001	1.02e-171	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLHFFEPM_01002	8.09e-207	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HLHFFEPM_01003	7.42e-118	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HLHFFEPM_01004	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HLHFFEPM_01005	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HLHFFEPM_01006	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HLHFFEPM_01007	2.21e-275	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HLHFFEPM_01008	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HLHFFEPM_01009	2.77e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HLHFFEPM_01010	2.79e-294	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HLHFFEPM_01011	2.1e-94	-	-	-	-	-	-	-	-
HLHFFEPM_01012	8.39e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLHFFEPM_01013	8.5e-287	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHFFEPM_01014	2.47e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HLHFFEPM_01015	1.48e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLHFFEPM_01016	1.42e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLHFFEPM_01017	4.92e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLHFFEPM_01018	2.18e-246	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLHFFEPM_01019	9.73e-132	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HLHFFEPM_01020	7.34e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HLHFFEPM_01021	5.54e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HLHFFEPM_01022	2.44e-217	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLHFFEPM_01023	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HLHFFEPM_01024	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HLHFFEPM_01025	4.71e-112	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLHFFEPM_01026	2.1e-30	XK27_07210	-	-	S	-	-	-	B3 4 domain
HLHFFEPM_01027	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HLHFFEPM_01028	1.86e-34	-	-	-	S	-	-	-	Acyltransferase family
HLHFFEPM_01030	1e-59	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HLHFFEPM_01031	3.85e-33	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HLHFFEPM_01032	1.84e-34	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HLHFFEPM_01033	4.27e-49	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HLHFFEPM_01034	2.17e-84	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HLHFFEPM_01036	7.26e-51	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
HLHFFEPM_01037	4.15e-82	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HLHFFEPM_01038	1.22e-103	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
HLHFFEPM_01039	1.17e-62	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HLHFFEPM_01040	1.73e-137	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HLHFFEPM_01041	1.24e-125	epsB	-	-	M	-	-	-	biosynthesis protein
HLHFFEPM_01042	7.59e-191	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLHFFEPM_01043	8.24e-24	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HLHFFEPM_01044	9.19e-261	-	-	-	L	-	-	-	Integrase core domain
HLHFFEPM_01045	3.75e-163	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLHFFEPM_01046	1.32e-36	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HLHFFEPM_01047	4.63e-183	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLHFFEPM_01049	2.95e-106	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HLHFFEPM_01050	4.43e-172	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HLHFFEPM_01051	3.1e-95	-	-	-	L	-	-	-	Helix-turn-helix domain
HLHFFEPM_01052	0.0	ade	-	-	F	-	-	-	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLHFFEPM_01053	1.64e-233	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HLHFFEPM_01054	1.15e-207	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HLHFFEPM_01055	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HLHFFEPM_01056	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HLHFFEPM_01057	7.28e-59	-	-	-	V	-	-	-	DNA restriction-modification system
HLHFFEPM_01058	9.02e-27	-	-	-	LV	-	-	-	TaqI-like C-terminal specificity domain
HLHFFEPM_01059	3.83e-100	-	-	-	V	-	-	-	DNA restriction-modification system
HLHFFEPM_01060	5.16e-289	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HLHFFEPM_01061	1.2e-205	-	-	-	J	-	-	-	Methyltransferase
HLHFFEPM_01062	5.18e-114	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HLHFFEPM_01063	3.4e-66	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HLHFFEPM_01064	2.74e-50	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HLHFFEPM_01065	1.21e-251	-	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_01066	7.18e-173	-	-	-	M	-	-	-	Lysin motif
HLHFFEPM_01067	3.29e-104	-	-	-	-	-	-	-	-
HLHFFEPM_01068	9.81e-36	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HLHFFEPM_01069	8.46e-07	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLHFFEPM_01070	1.22e-102	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLHFFEPM_01071	1.2e-264	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HLHFFEPM_01072	3.7e-19	-	-	-	-	-	-	-	-
HLHFFEPM_01073	6.32e-161	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_01074	5.75e-52	-	-	-	S	-	-	-	Cytochrome B5
HLHFFEPM_01075	4.27e-48	-	-	-	L	-	-	-	Helix-turn-helix domain
HLHFFEPM_01076	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HLHFFEPM_01077	3.19e-45	-	-	-	C	-	-	-	Heavy-metal-associated domain
HLHFFEPM_01078	2.47e-119	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HLHFFEPM_01079	5.87e-147	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HLHFFEPM_01080	7.04e-22	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HLHFFEPM_01081	1.9e-107	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HLHFFEPM_01082	4e-79	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HLHFFEPM_01083	2.78e-30	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HLHFFEPM_01084	2e-184	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HLHFFEPM_01085	3.23e-149	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HLHFFEPM_01086	9.73e-85	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HLHFFEPM_01087	1.13e-26	-	-	-	-	-	-	-	-
HLHFFEPM_01088	8.57e-71	-	-	-	S	-	-	-	Bacteriophage holin family
HLHFFEPM_01089	5.85e-73	-	-	-	S	-	-	-	Phage head-tail joining protein
HLHFFEPM_01090	1.34e-52	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HLHFFEPM_01091	8.27e-235	-	-	-	S	-	-	-	Phage capsid family
HLHFFEPM_01092	1.27e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLHFFEPM_01093	8.85e-164	-	-	-	F	-	-	-	NUDIX domain
HLHFFEPM_01094	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLHFFEPM_01095	3.18e-133	pncA	-	-	Q	-	-	-	Isochorismatase family
HLHFFEPM_01096	2.7e-18	XK27_09155	-	-	K	-	-	-	Transcriptional
HLHFFEPM_01097	3.39e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HLHFFEPM_01098	3.57e-74	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
HLHFFEPM_01099	1.31e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLHFFEPM_01100	1.78e-232	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HLHFFEPM_01101	1.73e-56	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HLHFFEPM_01102	1.47e-81	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLHFFEPM_01103	1.17e-56	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HLHFFEPM_01104	4.15e-23	-	-	-	K	-	-	-	Helix-turn-helix domain
HLHFFEPM_01105	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HLHFFEPM_01106	3.82e-182	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HLHFFEPM_01107	2.85e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HLHFFEPM_01108	7.21e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLHFFEPM_01109	3.36e-289	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HLHFFEPM_01110	1.07e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HLHFFEPM_01111	8.04e-63	-	-	-	-	-	-	-	-
HLHFFEPM_01112	4.23e-41	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
HLHFFEPM_01114	9.17e-70	-	-	-	-	-	-	-	-
HLHFFEPM_01115	1.43e-152	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HLHFFEPM_01117	2.01e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HLHFFEPM_01118	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HLHFFEPM_01119	1.2e-260	-	-	-	S	-	-	-	associated with various cellular activities
HLHFFEPM_01120	2.5e-296	-	-	-	S	-	-	-	Putative metallopeptidase domain
HLHFFEPM_01121	8.55e-64	-	-	-	-	-	-	-	-
HLHFFEPM_01122	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HLHFFEPM_01123	1.51e-137	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLHFFEPM_01124	2.55e-114	ymdB	-	-	S	-	-	-	Macro domain protein
HLHFFEPM_01125	1.16e-249	-	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_01126	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHFFEPM_01127	7.86e-13	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HLHFFEPM_01128	7.55e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HLHFFEPM_01129	3.31e-200	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HLHFFEPM_01130	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HLHFFEPM_01131	1.38e-171	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01132	1.19e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HLHFFEPM_01133	2.51e-160	XK27_10500	-	-	K	-	-	-	response regulator
HLHFFEPM_01134	3.44e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
HLHFFEPM_01135	2.68e-173	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HLHFFEPM_01136	1.59e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLHFFEPM_01137	4.14e-257	-	-	-	-	-	-	-	-
HLHFFEPM_01138	1.76e-68	-	-	-	-	-	-	-	-
HLHFFEPM_01139	1.21e-48	-	-	-	-	-	-	-	-
HLHFFEPM_01140	9.21e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HLHFFEPM_01141	4.49e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HLHFFEPM_01142	1.89e-227	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HLHFFEPM_01143	4.92e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLHFFEPM_01144	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HLHFFEPM_01145	1.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HLHFFEPM_01146	2.19e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HLHFFEPM_01147	4.51e-236	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLHFFEPM_01148	2.46e-47	-	-	-	M	-	-	-	Rib/alpha-like repeat
HLHFFEPM_01149	3.22e-304	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HLHFFEPM_01150	5.57e-164	-	-	-	IQ	-	-	-	dehydrogenase reductase
HLHFFEPM_01151	4.54e-49	-	-	-	-	-	-	-	-
HLHFFEPM_01152	9.4e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HLHFFEPM_01153	5.43e-51	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HLHFFEPM_01154	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HLHFFEPM_01155	1.09e-229	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLHFFEPM_01157	1.34e-127	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HLHFFEPM_01158	3.45e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HLHFFEPM_01159	5.03e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLHFFEPM_01161	2.69e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
HLHFFEPM_01162	6.97e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HLHFFEPM_01163	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HLHFFEPM_01165	1.28e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HLHFFEPM_01166	1.85e-69	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HLHFFEPM_01167	4.29e-162	-	-	-	-	-	-	-	-
HLHFFEPM_01168	1.12e-162	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HLHFFEPM_01169	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HLHFFEPM_01170	1.4e-280	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HLHFFEPM_01171	4.44e-11	-	-	-	-	-	-	-	-
HLHFFEPM_01172	1.89e-45	-	-	-	GM	-	-	-	NAD(P)H-binding
HLHFFEPM_01173	7.59e-66	-	-	-	GM	-	-	-	NAD(P)H-binding
HLHFFEPM_01174	3.05e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_01175	3.07e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HLHFFEPM_01176	6.73e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHFFEPM_01177	3.69e-183	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01178	1.32e-136	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HLHFFEPM_01179	7.7e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HLHFFEPM_01180	4.29e-82	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLHFFEPM_01181	2.48e-274	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLHFFEPM_01182	2.25e-55	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLHFFEPM_01183	2.71e-71	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HLHFFEPM_01184	2.1e-270	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HLHFFEPM_01185	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHFFEPM_01186	2e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLHFFEPM_01187	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HLHFFEPM_01188	4.93e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLHFFEPM_01189	1.7e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HLHFFEPM_01190	5.74e-54	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HLHFFEPM_01191	2.83e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLHFFEPM_01192	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HLHFFEPM_01193	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLHFFEPM_01195	7.39e-66	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLHFFEPM_01196	4.7e-21	-	-	-	EG	-	-	-	EamA-like transporter family
HLHFFEPM_01197	1.94e-21	-	-	-	EG	-	-	-	PFAM EamA-like transporter family
HLHFFEPM_01198	4.28e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HLHFFEPM_01199	4.06e-103	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HLHFFEPM_01200	3.85e-24	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HLHFFEPM_01201	1.86e-227	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHFFEPM_01202	1.64e-23	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
HLHFFEPM_01203	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01204	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HLHFFEPM_01205	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HLHFFEPM_01206	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHFFEPM_01207	1.85e-110	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLHFFEPM_01208	8.56e-162	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HLHFFEPM_01209	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HLHFFEPM_01210	7.66e-23	-	-	-	E	-	-	-	amino acid
HLHFFEPM_01211	6.26e-143	-	-	-	E	-	-	-	amino acid
HLHFFEPM_01212	9.91e-102	-	-	-	E	-	-	-	amino acid
HLHFFEPM_01213	2.91e-176	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HLHFFEPM_01214	2.45e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HLHFFEPM_01215	2.96e-211	-	-	-	GK	-	-	-	ROK family
HLHFFEPM_01216	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HLHFFEPM_01217	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HLHFFEPM_01218	2.02e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HLHFFEPM_01219	1.78e-83	-	-	-	-	-	-	-	-
HLHFFEPM_01220	5.68e-12	-	-	-	IQ	-	-	-	KR domain
HLHFFEPM_01221	1.1e-144	-	-	-	IQ	-	-	-	KR domain
HLHFFEPM_01222	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HLHFFEPM_01223	4.26e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HLHFFEPM_01224	1.1e-312	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01225	8.34e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLHFFEPM_01226	6.5e-71	-	-	-	-	-	-	-	-
HLHFFEPM_01227	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLHFFEPM_01228	2.59e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HLHFFEPM_01229	4.14e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HLHFFEPM_01230	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_01231	4.53e-203	-	-	-	-	-	-	-	-
HLHFFEPM_01232	9.72e-167	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLHFFEPM_01233	6.43e-214	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLHFFEPM_01234	1.4e-109	-	-	-	K	-	-	-	FCD
HLHFFEPM_01235	1.37e-213	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HLHFFEPM_01236	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HLHFFEPM_01237	5.64e-267	-	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_01238	2.76e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HLHFFEPM_01239	6.17e-38	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLHFFEPM_01240	6.46e-250	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLHFFEPM_01241	2.68e-36	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLHFFEPM_01242	9.4e-178	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HLHFFEPM_01243	8.05e-178	-	-	-	S	-	-	-	Membrane
HLHFFEPM_01244	1.36e-96	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HLHFFEPM_01245	8.27e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HLHFFEPM_01246	1.27e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HLHFFEPM_01247	5.13e-61	-	-	-	-	-	-	-	-
HLHFFEPM_01248	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HLHFFEPM_01249	2.52e-263	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HLHFFEPM_01250	2.95e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
HLHFFEPM_01251	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HLHFFEPM_01252	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HLHFFEPM_01253	2.32e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HLHFFEPM_01254	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HLHFFEPM_01255	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLHFFEPM_01256	1.53e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLHFFEPM_01257	1.23e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLHFFEPM_01258	7.38e-274	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HLHFFEPM_01259	8.55e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HLHFFEPM_01260	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HLHFFEPM_01261	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HLHFFEPM_01262	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HLHFFEPM_01263	4.97e-307	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLHFFEPM_01264	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HLHFFEPM_01265	7.36e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HLHFFEPM_01266	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLHFFEPM_01267	7.51e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLHFFEPM_01268	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLHFFEPM_01269	3.96e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLHFFEPM_01270	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLHFFEPM_01271	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLHFFEPM_01272	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HLHFFEPM_01273	1.39e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HLHFFEPM_01274	5.74e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HLHFFEPM_01275	1.65e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HLHFFEPM_01276	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLHFFEPM_01277	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLHFFEPM_01278	1.01e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLHFFEPM_01279	1.09e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLHFFEPM_01280	9.58e-211	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLHFFEPM_01281	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLHFFEPM_01282	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HLHFFEPM_01283	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HLHFFEPM_01284	2.82e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HLHFFEPM_01285	3.26e-296	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HLHFFEPM_01286	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HLHFFEPM_01287	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HLHFFEPM_01288	1.96e-292	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HLHFFEPM_01289	8.72e-235	ampC	-	-	V	-	-	-	Beta-lactamase
HLHFFEPM_01290	4.96e-64	-	-	-	-	-	-	-	-
HLHFFEPM_01291	1.28e-69	-	-	-	M	-	-	-	domain protein
HLHFFEPM_01292	5.51e-147	-	-	-	M	-	-	-	domain protein
HLHFFEPM_01293	8.79e-176	-	-	-	M	-	-	-	domain protein
HLHFFEPM_01294	6.45e-160	-	-	-	M	-	-	-	domain protein
HLHFFEPM_01295	4.73e-137	-	-	-	-	-	-	-	-
HLHFFEPM_01297	1.18e-57	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLHFFEPM_01298	2.33e-146	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLHFFEPM_01299	3.53e-49	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HLHFFEPM_01300	1.5e-74	-	-	-	-	-	-	-	-
HLHFFEPM_01302	6.11e-111	-	-	-	-	-	-	-	-
HLHFFEPM_01303	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HLHFFEPM_01304	1.26e-79	-	-	-	S	-	-	-	Cupredoxin-like domain
HLHFFEPM_01305	1.17e-132	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HLHFFEPM_01306	3.71e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HLHFFEPM_01307	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HLHFFEPM_01308	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLHFFEPM_01309	1.06e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HLHFFEPM_01310	3.42e-41	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HLHFFEPM_01312	1.1e-35	-	-	-	-	-	-	-	-
HLHFFEPM_01313	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HLHFFEPM_01314	1.07e-138	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HLHFFEPM_01315	4.16e-29	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HLHFFEPM_01316	9.45e-145	-	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_01319	4.54e-111	-	-	-	S	-	-	-	Protein conserved in bacteria
HLHFFEPM_01320	1.95e-228	-	-	-	-	-	-	-	-
HLHFFEPM_01321	1.39e-202	-	-	-	-	-	-	-	-
HLHFFEPM_01322	1.08e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HLHFFEPM_01323	2.72e-129	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLHFFEPM_01324	1.28e-18	-	-	-	-	-	-	-	-
HLHFFEPM_01325	1.7e-50	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHFFEPM_01326	2.07e-40	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHFFEPM_01327	3.18e-122	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HLHFFEPM_01328	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLHFFEPM_01329	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HLHFFEPM_01330	5.62e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLHFFEPM_01331	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HLHFFEPM_01332	1.09e-87	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HLHFFEPM_01333	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HLHFFEPM_01334	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HLHFFEPM_01335	6.64e-78	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HLHFFEPM_01336	1.38e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLHFFEPM_01337	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLHFFEPM_01338	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HLHFFEPM_01339	0.0	-	-	-	S	-	-	-	membrane
HLHFFEPM_01340	2.49e-87	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HLHFFEPM_01341	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLHFFEPM_01342	2.8e-150	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HLHFFEPM_01343	3.43e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
HLHFFEPM_01344	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLHFFEPM_01345	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLHFFEPM_01346	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLHFFEPM_01347	7.57e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLHFFEPM_01348	2.71e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLHFFEPM_01349	2.36e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HLHFFEPM_01350	6.44e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLHFFEPM_01351	1.52e-89	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HLHFFEPM_01352	1.24e-296	-	-	-	V	-	-	-	MatE
HLHFFEPM_01353	0.0	potE	-	-	E	-	-	-	Amino Acid
HLHFFEPM_01354	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HLHFFEPM_01355	9.72e-156	csrR	-	-	K	-	-	-	response regulator
HLHFFEPM_01356	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HLHFFEPM_01357	8.29e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HLHFFEPM_01358	8.54e-268	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HLHFFEPM_01359	5.88e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
HLHFFEPM_01360	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLHFFEPM_01361	4.71e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HLHFFEPM_01362	4.52e-154	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLHFFEPM_01363	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HLHFFEPM_01364	7.72e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HLHFFEPM_01365	7.47e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HLHFFEPM_01366	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HLHFFEPM_01367	6.89e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HLHFFEPM_01368	1.69e-44	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HLHFFEPM_01369	2.16e-121	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HLHFFEPM_01370	2.14e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HLHFFEPM_01371	2.33e-224	yagE	-	-	E	-	-	-	amino acid
HLHFFEPM_01372	6.54e-28	yagE	-	-	E	-	-	-	amino acid
HLHFFEPM_01373	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HLHFFEPM_01374	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HLHFFEPM_01375	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HLHFFEPM_01376	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HLHFFEPM_01377	7.67e-251	-	-	-	L	-	-	-	Transposase
HLHFFEPM_01382	1.02e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HLHFFEPM_01383	2.06e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLHFFEPM_01384	2.05e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HLHFFEPM_01385	4.22e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HLHFFEPM_01387	1.37e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HLHFFEPM_01388	5.6e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HLHFFEPM_01389	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HLHFFEPM_01390	1.15e-25	-	-	-	-	-	-	-	-
HLHFFEPM_01391	6.43e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HLHFFEPM_01392	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HLHFFEPM_01393	2.26e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HLHFFEPM_01394	8.32e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HLHFFEPM_01395	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLHFFEPM_01396	4.69e-200	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HLHFFEPM_01397	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HLHFFEPM_01399	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLHFFEPM_01400	7.36e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLHFFEPM_01401	2.67e-154	-	-	-	S	-	-	-	SNARE associated Golgi protein
HLHFFEPM_01402	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HLHFFEPM_01403	2.56e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLHFFEPM_01404	4.18e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLHFFEPM_01405	2.79e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLHFFEPM_01406	3.01e-185	-	-	-	S	-	-	-	DUF218 domain
HLHFFEPM_01407	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HLHFFEPM_01408	1.84e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
HLHFFEPM_01409	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HLHFFEPM_01410	1.18e-308	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HLHFFEPM_01411	3.87e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
HLHFFEPM_01412	7.71e-102	-	-	-	S	-	-	-	Cupin domain
HLHFFEPM_01413	5.42e-105	-	-	-	C	-	-	-	Flavodoxin
HLHFFEPM_01414	7.79e-204	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HLHFFEPM_01415	5.56e-214	yvgN	-	-	C	-	-	-	Aldo keto reductase
HLHFFEPM_01416	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HLHFFEPM_01417	4.27e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HLHFFEPM_01418	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHFFEPM_01419	5.06e-198	-	-	-	S	-	-	-	Alpha beta hydrolase
HLHFFEPM_01420	3.16e-197	gspA	-	-	M	-	-	-	family 8
HLHFFEPM_01421	2.4e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HLHFFEPM_01422	1.18e-120	-	-	-	-	-	-	-	-
HLHFFEPM_01423	3.45e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HLHFFEPM_01424	5.23e-204	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HLHFFEPM_01425	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HLHFFEPM_01426	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLHFFEPM_01427	5.29e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HLHFFEPM_01428	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLHFFEPM_01429	1.26e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLHFFEPM_01430	7.39e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HLHFFEPM_01431	1.55e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HLHFFEPM_01432	5.93e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HLHFFEPM_01433	3.2e-185	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HLHFFEPM_01434	1.1e-91	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
HLHFFEPM_01435	4.47e-95	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HLHFFEPM_01436	2.56e-152	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HLHFFEPM_01437	1.41e-98	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
HLHFFEPM_01438	3.91e-305	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HLHFFEPM_01439	5.59e-223	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HLHFFEPM_01440	6.56e-174	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HLHFFEPM_01441	6.66e-246	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HLHFFEPM_01442	3.85e-75	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
HLHFFEPM_01443	3.39e-303	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HLHFFEPM_01444	7.19e-155	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
HLHFFEPM_01445	1.88e-131	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HLHFFEPM_01446	8.36e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HLHFFEPM_01447	1.64e-159	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HLHFFEPM_01448	5.52e-117	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HLHFFEPM_01449	1.39e-138	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
HLHFFEPM_01450	1.88e-220	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HLHFFEPM_01451	1.43e-123	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
HLHFFEPM_01452	2.29e-165	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HLHFFEPM_01453	3.13e-181	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
HLHFFEPM_01454	5.75e-165	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HLHFFEPM_01455	7.05e-100	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HLHFFEPM_01456	6.19e-102	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HLHFFEPM_01457	1.39e-244	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HLHFFEPM_01458	4.7e-140	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
HLHFFEPM_01459	4.35e-186	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HLHFFEPM_01460	6.68e-258	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HLHFFEPM_01461	6.95e-216	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
HLHFFEPM_01462	1.72e-102	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
HLHFFEPM_01463	3.3e-145	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HLHFFEPM_01464	4.54e-95	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HLHFFEPM_01465	1.44e-90	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
HLHFFEPM_01466	3.45e-87	-	-	-	P	-	-	-	Cadmium resistance transporter
HLHFFEPM_01467	1.06e-96	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HLHFFEPM_01468	1.08e-147	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
HLHFFEPM_01469	9.15e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
HLHFFEPM_01470	2.06e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLHFFEPM_01471	2.5e-258	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
HLHFFEPM_01472	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HLHFFEPM_01473	1.62e-101	pduO	-	-	S	-	-	-	Haem-degrading
HLHFFEPM_01474	9.96e-135	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HLHFFEPM_01475	5.63e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
HLHFFEPM_01476	1.25e-103	-	-	-	S	-	-	-	Putative propanediol utilisation
HLHFFEPM_01477	1.98e-148	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HLHFFEPM_01478	3.65e-53	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
HLHFFEPM_01479	2.67e-74	-	-	-	CQ	-	-	-	BMC
HLHFFEPM_01480	4.57e-60	pduH	-	-	S	-	-	-	Dehydratase medium subunit
HLHFFEPM_01481	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
HLHFFEPM_01482	8.85e-97	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
HLHFFEPM_01483	5e-162	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
HLHFFEPM_01484	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
HLHFFEPM_01485	3.41e-170	pduB	-	-	E	-	-	-	BMC
HLHFFEPM_01486	2.33e-50	-	-	-	CQ	-	-	-	BMC
HLHFFEPM_01487	1.69e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLHFFEPM_01488	4.02e-177	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
HLHFFEPM_01489	9.82e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HLHFFEPM_01490	6.77e-204	-	-	-	-	-	-	-	-
HLHFFEPM_01491	8.07e-199	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HLHFFEPM_01492	1.69e-227	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HLHFFEPM_01493	7.13e-169	XK27_07210	-	-	S	-	-	-	B3 4 domain
HLHFFEPM_01494	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_01495	5.04e-116	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HLHFFEPM_01496	9.43e-116	-	-	-	GM	-	-	-	epimerase
HLHFFEPM_01497	7.72e-196	-	-	-	V	-	-	-	(ABC) transporter
HLHFFEPM_01498	6.23e-303	yhdP	-	-	S	-	-	-	Transporter associated domain
HLHFFEPM_01499	1.57e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HLHFFEPM_01500	4.3e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HLHFFEPM_01501	7.93e-242	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HLHFFEPM_01502	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLHFFEPM_01503	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLHFFEPM_01504	1.02e-51	-	-	-	-	-	-	-	-
HLHFFEPM_01505	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HLHFFEPM_01506	1.11e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HLHFFEPM_01507	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HLHFFEPM_01508	1.69e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HLHFFEPM_01509	7.68e-151	-	-	-	I	-	-	-	phosphatase
HLHFFEPM_01510	8.68e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HLHFFEPM_01511	5.75e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLHFFEPM_01512	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HLHFFEPM_01513	3.16e-159	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HLHFFEPM_01514	1.58e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HLHFFEPM_01515	2.99e-151	-	-	-	S	-	-	-	membrane
HLHFFEPM_01516	7.81e-141	-	-	-	S	-	-	-	VIT family
HLHFFEPM_01517	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HLHFFEPM_01518	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01519	5.46e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHFFEPM_01520	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHFFEPM_01521	1.48e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHFFEPM_01522	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HLHFFEPM_01523	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLHFFEPM_01524	3.88e-73	-	-	-	-	-	-	-	-
HLHFFEPM_01525	3.09e-97	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HLHFFEPM_01526	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HLHFFEPM_01527	1.26e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HLHFFEPM_01528	1.84e-204	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLHFFEPM_01530	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLHFFEPM_01531	7.62e-132	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HLHFFEPM_01532	2.16e-238	-	-	-	I	-	-	-	Alpha beta
HLHFFEPM_01533	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_01534	1.91e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HLHFFEPM_01535	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HLHFFEPM_01536	2.81e-202	-	-	-	K	-	-	-	LysR family
HLHFFEPM_01537	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HLHFFEPM_01538	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HLHFFEPM_01539	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLHFFEPM_01540	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HLHFFEPM_01541	1.44e-202	mleR	-	-	K	-	-	-	LysR family
HLHFFEPM_01542	6.76e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLHFFEPM_01543	7.79e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HLHFFEPM_01544	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HLHFFEPM_01545	6.38e-215	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HLHFFEPM_01546	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HLHFFEPM_01547	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLHFFEPM_01548	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLHFFEPM_01549	1.53e-268	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLHFFEPM_01550	1.11e-102	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HLHFFEPM_01551	1.41e-38	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HLHFFEPM_01552	1.15e-40	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HLHFFEPM_01554	2.96e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HLHFFEPM_01555	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLHFFEPM_01556	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLHFFEPM_01557	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HLHFFEPM_01558	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLHFFEPM_01559	8.88e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HLHFFEPM_01560	7.41e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLHFFEPM_01561	2.95e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLHFFEPM_01562	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HLHFFEPM_01563	5.49e-262	yacL	-	-	S	-	-	-	domain protein
HLHFFEPM_01564	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLHFFEPM_01565	4.86e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HLHFFEPM_01566	4.73e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HLHFFEPM_01567	5.89e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HLHFFEPM_01568	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HLHFFEPM_01569	1.95e-177	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HLHFFEPM_01570	1.01e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01571	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHFFEPM_01572	1.74e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HLHFFEPM_01573	8.91e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HLHFFEPM_01574	2.92e-170	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLHFFEPM_01575	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HLHFFEPM_01576	1.57e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HLHFFEPM_01577	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HLHFFEPM_01579	6.46e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HLHFFEPM_01580	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HLHFFEPM_01581	1.02e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLHFFEPM_01582	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLHFFEPM_01583	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HLHFFEPM_01584	3.53e-168	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HLHFFEPM_01585	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HLHFFEPM_01586	3.57e-316	-	-	-	EGP	-	-	-	Major Facilitator
HLHFFEPM_01587	2.68e-144	-	-	-	-	-	-	-	-
HLHFFEPM_01590	1.76e-79	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLHFFEPM_01591	1.68e-100	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HLHFFEPM_01592	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HLHFFEPM_01596	5.51e-49	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLHFFEPM_01597	1.01e-207	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLHFFEPM_01598	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HLHFFEPM_01599	1.01e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHFFEPM_01600	4.43e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HLHFFEPM_01601	4.03e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHFFEPM_01602	3.93e-45	-	-	-	-	-	-	-	-
HLHFFEPM_01603	6.69e-77	-	-	-	-	-	-	-	-
HLHFFEPM_01604	1.51e-51	-	-	-	-	-	-	-	-
HLHFFEPM_01605	3.54e-179	-	-	-	L	-	-	-	Bacterial dnaA protein
HLHFFEPM_01606	9.7e-294	-	-	-	L	-	-	-	Integrase core domain
HLHFFEPM_01607	2.34e-78	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLHFFEPM_01608	4.08e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HLHFFEPM_01609	0.0	-	-	-	L	-	-	-	DNA helicase
HLHFFEPM_01610	2.23e-113	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLHFFEPM_01611	2.49e-123	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLHFFEPM_01612	7.57e-103	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLHFFEPM_01613	2.44e-266	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HLHFFEPM_01614	3.55e-313	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HLHFFEPM_01615	5.61e-108	yvbK	-	-	K	-	-	-	GNAT family
HLHFFEPM_01616	7.41e-120	-	-	-	-	-	-	-	-
HLHFFEPM_01617	7.82e-161	pnb	-	-	C	-	-	-	nitroreductase
HLHFFEPM_01618	1.52e-108	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HLHFFEPM_01619	3.35e-216	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HLHFFEPM_01620	2.62e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HLHFFEPM_01621	2.03e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
HLHFFEPM_01622	1.46e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HLHFFEPM_01623	1.21e-26	-	-	-	-	-	-	-	-
HLHFFEPM_01624	3.86e-95	-	-	-	P	-	-	-	Major Facilitator Superfamily
HLHFFEPM_01625	2.64e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HLHFFEPM_01626	4.36e-103	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HLHFFEPM_01627	1.6e-246	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HLHFFEPM_01628	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HLHFFEPM_01629	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLHFFEPM_01630	2.95e-135	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HLHFFEPM_01631	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HLHFFEPM_01632	1.08e-244	mocA	-	-	S	-	-	-	Oxidoreductase
HLHFFEPM_01633	4.69e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HLHFFEPM_01635	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLHFFEPM_01636	3.98e-15	-	-	-	-	-	-	-	-
HLHFFEPM_01637	2.45e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HLHFFEPM_01638	9.49e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HLHFFEPM_01639	4.08e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HLHFFEPM_01640	1.97e-280	arcT	-	-	E	-	-	-	Aminotransferase
HLHFFEPM_01641	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HLHFFEPM_01642	0.0	potE	-	-	E	-	-	-	Amino Acid
HLHFFEPM_01643	3.38e-195	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HLHFFEPM_01644	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HLHFFEPM_01645	8.83e-43	-	-	-	-	-	-	-	-
HLHFFEPM_01646	4.55e-172	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HLHFFEPM_01647	2.23e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HLHFFEPM_01648	5.18e-221	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HLHFFEPM_01649	4.01e-153	-	-	-	M	-	-	-	Bacterial sugar transferase
HLHFFEPM_01650	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HLHFFEPM_01651	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
HLHFFEPM_01652	3.83e-39	-	-	-	-	-	-	-	-
HLHFFEPM_01653	1.23e-278	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HLHFFEPM_01654	8.05e-264	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HLHFFEPM_01655	1.51e-95	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HLHFFEPM_01656	8.66e-108	-	-	-	-	-	-	-	-
HLHFFEPM_01657	2.42e-38	-	-	-	M	-	-	-	biosynthesis protein
HLHFFEPM_01658	3.13e-95	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HLHFFEPM_01659	1.1e-84	-	-	-	S	-	-	-	Glycosyltransferase like family
HLHFFEPM_01660	4.04e-97	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
HLHFFEPM_01661	1.14e-89	-	-	-	S	-	-	-	Acyltransferase family
HLHFFEPM_01662	2.96e-95	-	-	-	-	-	-	-	-
HLHFFEPM_01663	4.52e-184	-	-	-	M	-	-	-	Glycosyl transferase family 2
HLHFFEPM_01664	1.74e-173	-	-	-	-	-	-	-	-
HLHFFEPM_01665	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLHFFEPM_01666	1.58e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLHFFEPM_01667	7.93e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HLHFFEPM_01668	1.34e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLHFFEPM_01669	6.42e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLHFFEPM_01670	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HLHFFEPM_01671	3.74e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
HLHFFEPM_01672	6.84e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HLHFFEPM_01673	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HLHFFEPM_01674	0.0	-	-	-	M	-	-	-	NlpC/P60 family
HLHFFEPM_01675	0.0	-	-	-	S	-	-	-	Peptidase, M23
HLHFFEPM_01676	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HLHFFEPM_01677	3.55e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01678	7.04e-149	-	-	-	-	-	-	-	-
HLHFFEPM_01679	3.86e-182	-	-	-	G	-	-	-	MucBP domain
HLHFFEPM_01680	1.82e-129	-	-	-	S	-	-	-	Pfam:DUF3816
HLHFFEPM_01681	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HLHFFEPM_01682	5.62e-37	-	-	-	-	-	-	-	-
HLHFFEPM_01683	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HLHFFEPM_01684	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLHFFEPM_01685	1.8e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HLHFFEPM_01686	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HLHFFEPM_01687	9.33e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLHFFEPM_01688	5.67e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HLHFFEPM_01689	1.18e-173	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HLHFFEPM_01690	4.31e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLHFFEPM_01691	1.77e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HLHFFEPM_01692	7.16e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HLHFFEPM_01693	1.64e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HLHFFEPM_01694	1.97e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLHFFEPM_01695	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HLHFFEPM_01696	1.65e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLHFFEPM_01697	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLHFFEPM_01698	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLHFFEPM_01699	1.16e-114	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLHFFEPM_01700	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HLHFFEPM_01701	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLHFFEPM_01702	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLHFFEPM_01703	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HLHFFEPM_01704	1.13e-170	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HLHFFEPM_01705	6.31e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HLHFFEPM_01706	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HLHFFEPM_01707	3.29e-62	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLHFFEPM_01708	3.05e-49	-	-	-	-	-	-	-	-
HLHFFEPM_01710	8.73e-28	-	-	-	-	-	-	-	-
HLHFFEPM_01712	3.34e-96	-	-	-	L	-	-	-	Replication protein
HLHFFEPM_01715	8.85e-102	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HLHFFEPM_01716	6.01e-122	-	-	-	S	-	-	-	FRG
HLHFFEPM_01717	7.01e-78	-	-	-	S	-	-	-	FRG
HLHFFEPM_01718	4.84e-267	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HLHFFEPM_01719	4.05e-107	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLHFFEPM_01720	2.52e-68	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLHFFEPM_01721	1.63e-81	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLHFFEPM_01722	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLHFFEPM_01723	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HLHFFEPM_01724	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HLHFFEPM_01725	9.42e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HLHFFEPM_01726	9.5e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLHFFEPM_01727	3.96e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLHFFEPM_01728	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HLHFFEPM_01729	4.27e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HLHFFEPM_01730	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLHFFEPM_01731	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLHFFEPM_01732	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLHFFEPM_01733	2.24e-143	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HLHFFEPM_01734	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HLHFFEPM_01735	1.44e-139	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HLHFFEPM_01737	5.08e-226	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HLHFFEPM_01738	6.23e-35	-	-	-	-	-	-	-	-
HLHFFEPM_01739	1.09e-122	-	-	-	-	-	-	-	-
HLHFFEPM_01740	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLHFFEPM_01741	3.28e-232	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLHFFEPM_01742	1.89e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HLHFFEPM_01743	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HLHFFEPM_01744	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HLHFFEPM_01745	2.2e-62	-	-	-	-	-	-	-	-
HLHFFEPM_01746	1.81e-41	-	-	-	-	-	-	-	-
HLHFFEPM_01747	7.29e-60	-	-	-	-	-	-	-	-
HLHFFEPM_01748	5.53e-127	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HLHFFEPM_01749	0.0	-	-	-	L	-	-	-	PLD-like domain
HLHFFEPM_01752	2.6e-135	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_01753	5.61e-292	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLHFFEPM_01754	2.7e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HLHFFEPM_01755	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
HLHFFEPM_01756	2.65e-56	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLHFFEPM_01757	1.62e-81	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HLHFFEPM_01758	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HLHFFEPM_01759	2.87e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLHFFEPM_01760	2.13e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HLHFFEPM_01761	3.96e-254	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HLHFFEPM_01762	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HLHFFEPM_01763	8.08e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
HLHFFEPM_01764	5.87e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HLHFFEPM_01765	1.46e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLHFFEPM_01766	9.29e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HLHFFEPM_01767	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HLHFFEPM_01768	9.89e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HLHFFEPM_01769	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HLHFFEPM_01770	2.76e-183	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLHFFEPM_01771	3.83e-22	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HLHFFEPM_01772	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLHFFEPM_01773	2.01e-130	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HLHFFEPM_01774	1.27e-259	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HLHFFEPM_01775	1.39e-225	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HLHFFEPM_01776	1.28e-35	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HLHFFEPM_01777	1.67e-45	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HLHFFEPM_01778	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLHFFEPM_01779	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HLHFFEPM_01780	3.28e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01781	2.51e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HLHFFEPM_01782	2.4e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HLHFFEPM_01783	8.26e-219	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HLHFFEPM_01784	1.47e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HLHFFEPM_01785	1.36e-157	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HLHFFEPM_01786	3.79e-193	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLHFFEPM_01787	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HLHFFEPM_01788	1.38e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HLHFFEPM_01789	2.37e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HLHFFEPM_01790	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLHFFEPM_01791	4.25e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HLHFFEPM_01792	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLHFFEPM_01793	4.64e-298	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLHFFEPM_01794	6.43e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HLHFFEPM_01795	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HLHFFEPM_01796	6.79e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HLHFFEPM_01797	8.49e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLHFFEPM_01798	9.76e-161	vanR	-	-	K	-	-	-	response regulator
HLHFFEPM_01799	9.17e-265	hpk31	-	-	T	-	-	-	Histidine kinase
HLHFFEPM_01800	9.75e-186	-	-	-	E	-	-	-	AzlC protein
HLHFFEPM_01801	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HLHFFEPM_01802	1.92e-90	-	-	-	K	-	-	-	LysR substrate binding domain
HLHFFEPM_01803	1.29e-25	-	-	-	K	-	-	-	LysR substrate binding domain
HLHFFEPM_01804	2.57e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HLHFFEPM_01805	7.42e-314	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLHFFEPM_01806	7.94e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLHFFEPM_01807	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLHFFEPM_01808	1.51e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLHFFEPM_01809	7.47e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HLHFFEPM_01810	1.85e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLHFFEPM_01811	8.13e-292	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HLHFFEPM_01812	3.86e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
HLHFFEPM_01813	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HLHFFEPM_01814	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HLHFFEPM_01815	1.23e-163	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HLHFFEPM_01816	2.11e-24	mocA	-	-	S	-	-	-	Oxidoreductase
HLHFFEPM_01817	9.67e-31	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HLHFFEPM_01818	5.38e-234	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HLHFFEPM_01819	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HLHFFEPM_01820	1e-126	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLHFFEPM_01821	4.26e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLHFFEPM_01822	5.01e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLHFFEPM_01823	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLHFFEPM_01824	5.23e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HLHFFEPM_01825	4.5e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLHFFEPM_01826	1.98e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLHFFEPM_01827	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLHFFEPM_01828	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLHFFEPM_01829	4.6e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HLHFFEPM_01830	2.37e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLHFFEPM_01831	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HLHFFEPM_01832	1.66e-309	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HLHFFEPM_01833	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HLHFFEPM_01834	9.19e-226	-	-	-	-	-	-	-	-
HLHFFEPM_01835	6.7e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLHFFEPM_01836	2.21e-87	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HLHFFEPM_01838	5.69e-152	-	-	-	L	-	-	-	Integrase core domain
HLHFFEPM_01839	2.03e-141	-	-	-	L	-	-	-	Bacterial dnaA protein
HLHFFEPM_01847	1.12e-167	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HLHFFEPM_01848	3.64e-175	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HLHFFEPM_01849	1.45e-184	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLHFFEPM_01850	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HLHFFEPM_01851	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLHFFEPM_01852	4.19e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLHFFEPM_01853	5.28e-281	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLHFFEPM_01854	2.76e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HLHFFEPM_01855	4.93e-197	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HLHFFEPM_01856	1.99e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLHFFEPM_01857	1.12e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLHFFEPM_01858	1.94e-100	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HLHFFEPM_01859	1.39e-91	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLHFFEPM_01861	2.12e-254	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HLHFFEPM_01862	3.16e-111	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HLHFFEPM_01863	3.63e-120	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HLHFFEPM_01864	1.15e-200	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HLHFFEPM_01865	9.45e-152	-	-	-	L	-	-	-	Integrase
HLHFFEPM_01866	9.33e-197	-	-	-	EG	-	-	-	EamA-like transporter family
HLHFFEPM_01867	3.85e-167	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HLHFFEPM_01868	3.47e-129	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HLHFFEPM_01869	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HLHFFEPM_01870	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLHFFEPM_01871	4.32e-235	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HLHFFEPM_01872	1.65e-107	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HLHFFEPM_01873	3.34e-286	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HLHFFEPM_01874	2.25e-97	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HLHFFEPM_01875	4.55e-124	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HLHFFEPM_01876	5.25e-59	-	-	-	-	-	-	-	-
HLHFFEPM_01877	3.07e-241	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HLHFFEPM_01878	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HLHFFEPM_01879	1.54e-26	-	-	-	-	-	-	-	-
HLHFFEPM_01880	9.33e-226	-	-	-	-	-	-	-	-
HLHFFEPM_01881	1.9e-203	-	-	-	H	-	-	-	geranyltranstransferase activity
HLHFFEPM_01882	3.04e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HLHFFEPM_01883	5.33e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HLHFFEPM_01884	1.81e-81	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HLHFFEPM_01885	7.28e-101	-	-	-	S	-	-	-	Flavodoxin
HLHFFEPM_01886	1.77e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLHFFEPM_01887	2.02e-172	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLHFFEPM_01888	1.04e-226	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HLHFFEPM_01889	2.76e-221	-	-	-	-	-	-	-	-
HLHFFEPM_01890	1.75e-94	-	-	-	-	-	-	-	-
HLHFFEPM_01891	1.69e-33	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HLHFFEPM_01892	2.33e-29	-	-	-	-	-	-	-	-
HLHFFEPM_01893	1.23e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HLHFFEPM_01898	9.82e-69	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HLHFFEPM_01899	2e-181	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HLHFFEPM_01900	1.04e-248	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HLHFFEPM_01901	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HLHFFEPM_01902	4.35e-239	-	-	-	S	-	-	-	amidohydrolase
HLHFFEPM_01903	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
HLHFFEPM_01904	4.42e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HLHFFEPM_01905	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HLHFFEPM_01906	2.57e-141	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HLHFFEPM_01907	5.52e-116	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HLHFFEPM_01908	1.66e-235	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HLHFFEPM_01909	2.37e-162	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HLHFFEPM_01910	4.17e-69	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HLHFFEPM_01911	1.64e-84	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HLHFFEPM_01912	3.54e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HLHFFEPM_01913	1.66e-246	flp	-	-	V	-	-	-	Beta-lactamase
HLHFFEPM_01914	3.98e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HLHFFEPM_01915	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HLHFFEPM_01916	6.03e-183	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
HLHFFEPM_01917	1.61e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
HLHFFEPM_01918	2.6e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLHFFEPM_01919	4.77e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HLHFFEPM_01920	1.26e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLHFFEPM_01921	2.02e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HLHFFEPM_01922	1.61e-48	-	-	-	-	-	-	-	-
HLHFFEPM_01923	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01924	2.37e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HLHFFEPM_01925	7.46e-222	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HLHFFEPM_01926	1.46e-110	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HLHFFEPM_01927	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HLHFFEPM_01928	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HLHFFEPM_01929	2.94e-72	-	-	-	-	-	-	-	-
HLHFFEPM_01930	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLHFFEPM_01932	3.95e-07	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HLHFFEPM_01933	2.76e-256	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HLHFFEPM_01934	9.51e-127	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HLHFFEPM_01935	6.46e-73	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HLHFFEPM_01936	5.69e-314	-	-	-	E	ko:K03294	-	ko00000	amino acid
HLHFFEPM_01937	1.1e-152	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLHFFEPM_01939	1.02e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HLHFFEPM_01940	3.33e-39	-	-	-	S	-	-	-	Cytochrome B5
HLHFFEPM_01941	4.97e-97	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HLHFFEPM_01942	1.11e-156	-	-	-	GM	-	-	-	NmrA-like family
HLHFFEPM_01943	1.07e-66	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLHFFEPM_01944	6.45e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HLHFFEPM_01945	1.78e-106	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HLHFFEPM_01946	6.84e-293	-	-	-	-	-	-	-	-
HLHFFEPM_01947	2.65e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HLHFFEPM_01948	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HLHFFEPM_01949	8.37e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HLHFFEPM_01950	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HLHFFEPM_01951	1.08e-62	ywnA	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_01952	5.03e-34	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HLHFFEPM_01953	2.03e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HLHFFEPM_01954	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HLHFFEPM_01955	9.8e-156	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HLHFFEPM_01956	1.18e-245	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HLHFFEPM_01957	4.06e-108	-	-	-	-	-	-	-	-
HLHFFEPM_01958	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HLHFFEPM_01959	3.98e-176	-	-	-	T	-	-	-	EAL domain
HLHFFEPM_01960	4.69e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HLHFFEPM_01961	3.65e-78	-	-	-	-	-	-	-	-
HLHFFEPM_01962	9.48e-128	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HLHFFEPM_01963	6.67e-204	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HLHFFEPM_01964	4.06e-188	-	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_01965	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HLHFFEPM_01966	5.88e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HLHFFEPM_01967	1.67e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HLHFFEPM_01968	4.61e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HLHFFEPM_01969	4.88e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HLHFFEPM_01970	2.44e-114	-	-	-	S	-	-	-	Alpha beta hydrolase
HLHFFEPM_01971	3.49e-16	-	-	-	S	-	-	-	Alpha beta hydrolase
HLHFFEPM_01972	3.1e-170	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HLHFFEPM_01973	3.38e-110	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HLHFFEPM_01974	1.64e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
HLHFFEPM_01975	5.96e-32	-	-	-	-	-	-	-	-
HLHFFEPM_01976	5.39e-111	-	-	-	C	-	-	-	Flavodoxin
HLHFFEPM_01977	3.91e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HLHFFEPM_01978	4.31e-233	-	-	-	C	-	-	-	nadph quinone reductase
HLHFFEPM_01979	3.32e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HLHFFEPM_01980	4.64e-143	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HLHFFEPM_01981	6.46e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HLHFFEPM_01982	1.41e-117	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HLHFFEPM_01983	5.45e-282	-	-	-	T	-	-	-	GHKL domain
HLHFFEPM_01984	3.12e-151	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HLHFFEPM_01985	1.18e-201	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HLHFFEPM_01986	1.36e-117	-	-	-	L	-	-	-	PFAM Integrase catalytic region