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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HCBKGIIK_00001	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCBKGIIK_00002	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HCBKGIIK_00003	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HCBKGIIK_00004	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HCBKGIIK_00005	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCBKGIIK_00006	8.53e-95	-	-	-	-	-	-	-	-
HCBKGIIK_00007	4.05e-39	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HCBKGIIK_00008	2.53e-17	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HCBKGIIK_00009	1.11e-16	-	-	-	E	-	-	-	amino acid
HCBKGIIK_00011	1.82e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCBKGIIK_00012	1.56e-117	-	-	-	-	-	-	-	-
HCBKGIIK_00013	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCBKGIIK_00014	2.42e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCBKGIIK_00015	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HCBKGIIK_00016	3.77e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HCBKGIIK_00017	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HCBKGIIK_00018	1.48e-214	-	-	-	C	-	-	-	Aldo keto reductase
HCBKGIIK_00019	1.45e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HCBKGIIK_00020	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HCBKGIIK_00021	7.12e-275	-	-	-	P	-	-	-	Voltage gated chloride channel
HCBKGIIK_00022	1.32e-288	sptS	-	-	T	-	-	-	Histidine kinase
HCBKGIIK_00023	9.03e-153	dltr	-	-	K	-	-	-	response regulator
HCBKGIIK_00024	1.02e-111	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HCBKGIIK_00025	2.83e-90	-	-	-	-	-	-	-	-
HCBKGIIK_00026	1.02e-153	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HCBKGIIK_00027	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HCBKGIIK_00028	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCBKGIIK_00029	2.57e-272	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HCBKGIIK_00030	2.11e-221	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCBKGIIK_00031	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HCBKGIIK_00032	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCBKGIIK_00033	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBKGIIK_00034	9.22e-135	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HCBKGIIK_00036	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HCBKGIIK_00037	2.49e-43	-	-	-	-	-	-	-	-
HCBKGIIK_00038	1.13e-272	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCBKGIIK_00039	3.47e-221	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKGIIK_00040	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
HCBKGIIK_00041	1.79e-111	-	-	-	K	-	-	-	FR47-like protein
HCBKGIIK_00042	3.99e-68	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HCBKGIIK_00045	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HCBKGIIK_00046	4.34e-66	-	-	-	-	-	-	-	-
HCBKGIIK_00047	5.34e-270	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HCBKGIIK_00048	3.99e-166	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HCBKGIIK_00049	1.36e-198	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HCBKGIIK_00050	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HCBKGIIK_00051	2.13e-189	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBKGIIK_00052	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
HCBKGIIK_00053	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HCBKGIIK_00054	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HCBKGIIK_00055	6.12e-123	-	-	-	S	-	-	-	reductase
HCBKGIIK_00057	4.36e-114	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCBKGIIK_00058	1e-223	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HCBKGIIK_00059	1.47e-110	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HCBKGIIK_00061	7.56e-286	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HCBKGIIK_00062	1.46e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HCBKGIIK_00063	1.18e-191	yycI	-	-	S	-	-	-	YycH protein
HCBKGIIK_00064	1.09e-311	yycH	-	-	S	-	-	-	YycH protein
HCBKGIIK_00065	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCBKGIIK_00066	1.29e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HCBKGIIK_00068	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HCBKGIIK_00069	6.3e-95	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HCBKGIIK_00071	1.58e-157	-	-	-	S	-	-	-	Fic/DOC family
HCBKGIIK_00072	2.53e-208	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HCBKGIIK_00073	7.71e-81	-	-	-	-	-	-	-	-
HCBKGIIK_00074	9.25e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_00075	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HCBKGIIK_00076	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HCBKGIIK_00077	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HCBKGIIK_00078	1.73e-128	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HCBKGIIK_00079	2.33e-60	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCBKGIIK_00080	4.43e-41	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCBKGIIK_00081	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCBKGIIK_00082	1.34e-110	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCBKGIIK_00083	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HCBKGIIK_00084	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBKGIIK_00085	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBKGIIK_00086	2.7e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCBKGIIK_00087	1.09e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HCBKGIIK_00088	3.86e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCBKGIIK_00089	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCBKGIIK_00090	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HCBKGIIK_00091	1.39e-76	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCBKGIIK_00092	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBKGIIK_00093	8.89e-170	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HCBKGIIK_00094	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCBKGIIK_00095	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCBKGIIK_00096	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HCBKGIIK_00097	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCBKGIIK_00098	7.33e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HCBKGIIK_00099	3.47e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HCBKGIIK_00100	5.59e-20	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HCBKGIIK_00101	6.71e-61	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HCBKGIIK_00102	1.15e-93	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_00103	3.25e-43	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_00104	4.08e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HCBKGIIK_00105	0.0	-	-	-	L	-	-	-	DNA helicase
HCBKGIIK_00106	7.77e-261	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCBKGIIK_00108	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCBKGIIK_00109	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HCBKGIIK_00110	2.83e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCBKGIIK_00111	5.74e-54	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HCBKGIIK_00112	1.7e-280	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HCBKGIIK_00113	4.93e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCBKGIIK_00114	2.06e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCBKGIIK_00115	2e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCBKGIIK_00116	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCBKGIIK_00117	2.1e-270	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HCBKGIIK_00118	2.71e-71	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HCBKGIIK_00119	2.25e-55	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HCBKGIIK_00120	2.48e-274	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HCBKGIIK_00121	4.29e-82	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HCBKGIIK_00122	7.7e-104	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HCBKGIIK_00123	1.32e-136	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HCBKGIIK_00124	3.69e-183	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_00125	6.73e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCBKGIIK_00126	3.07e-208	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HCBKGIIK_00127	3.05e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_00128	7.59e-66	-	-	-	GM	-	-	-	NAD(P)H-binding
HCBKGIIK_00129	1.89e-45	-	-	-	GM	-	-	-	NAD(P)H-binding
HCBKGIIK_00130	4.44e-11	-	-	-	-	-	-	-	-
HCBKGIIK_00131	1.4e-280	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HCBKGIIK_00132	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HCBKGIIK_00133	1.12e-162	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HCBKGIIK_00134	4.29e-162	-	-	-	-	-	-	-	-
HCBKGIIK_00135	1.85e-69	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HCBKGIIK_00136	1.28e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HCBKGIIK_00138	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HCBKGIIK_00139	6.97e-105	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HCBKGIIK_00140	2.69e-227	ydhF	-	-	S	-	-	-	Aldo keto reductase
HCBKGIIK_00142	5.03e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCBKGIIK_00143	3.45e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HCBKGIIK_00144	1.34e-127	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HCBKGIIK_00146	1.09e-229	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCBKGIIK_00147	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HCBKGIIK_00148	5.43e-51	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HCBKGIIK_00149	9.4e-148	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HCBKGIIK_00150	4.54e-49	-	-	-	-	-	-	-	-
HCBKGIIK_00151	5.57e-164	-	-	-	IQ	-	-	-	dehydrogenase reductase
HCBKGIIK_00152	3.22e-304	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HCBKGIIK_00153	1.32e-16	-	-	-	M	-	-	-	Rib/alpha-like repeat
HCBKGIIK_00154	5.74e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HCBKGIIK_00155	3.2e-185	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HCBKGIIK_00156	1.1e-91	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
HCBKGIIK_00157	4.47e-95	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HCBKGIIK_00158	2.56e-152	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HCBKGIIK_00159	1.41e-98	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
HCBKGIIK_00160	3.91e-305	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HCBKGIIK_00161	5.59e-223	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HCBKGIIK_00162	6.56e-174	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HCBKGIIK_00163	6.66e-246	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HCBKGIIK_00164	3.85e-75	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
HCBKGIIK_00165	3.39e-303	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HCBKGIIK_00166	7.19e-155	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
HCBKGIIK_00167	1.88e-131	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCBKGIIK_00168	8.36e-59	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HCBKGIIK_00169	1.64e-159	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HCBKGIIK_00170	5.52e-117	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HCBKGIIK_00171	1.39e-138	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
HCBKGIIK_00172	1.88e-220	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HCBKGIIK_00173	1.43e-123	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
HCBKGIIK_00174	2.29e-165	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HCBKGIIK_00175	3.13e-181	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
HCBKGIIK_00176	5.75e-165	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HCBKGIIK_00177	7.05e-100	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HCBKGIIK_00178	6.19e-102	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HCBKGIIK_00179	1.39e-244	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HCBKGIIK_00180	4.7e-140	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
HCBKGIIK_00181	4.35e-186	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HCBKGIIK_00182	6.68e-258	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HCBKGIIK_00183	6.95e-216	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
HCBKGIIK_00184	1.72e-102	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
HCBKGIIK_00185	3.3e-145	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HCBKGIIK_00186	4.54e-95	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HCBKGIIK_00187	1.44e-90	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
HCBKGIIK_00188	3.45e-87	-	-	-	P	-	-	-	Cadmium resistance transporter
HCBKGIIK_00189	1.06e-96	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HCBKGIIK_00190	1.08e-147	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
HCBKGIIK_00191	9.15e-72	-	-	-	E	ko:K04031	-	ko00000	BMC
HCBKGIIK_00192	2.06e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBKGIIK_00193	2.5e-258	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
HCBKGIIK_00194	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HCBKGIIK_00195	1.62e-101	pduO	-	-	S	-	-	-	Haem-degrading
HCBKGIIK_00196	9.96e-135	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HCBKGIIK_00197	5.63e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
HCBKGIIK_00198	1.25e-103	-	-	-	S	-	-	-	Putative propanediol utilisation
HCBKGIIK_00199	1.98e-148	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HCBKGIIK_00200	3.65e-53	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
HCBKGIIK_00201	2.67e-74	-	-	-	CQ	-	-	-	BMC
HCBKGIIK_00202	4.57e-60	pduH	-	-	S	-	-	-	Dehydratase medium subunit
HCBKGIIK_00203	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
HCBKGIIK_00204	8.85e-97	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
HCBKGIIK_00205	5e-162	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
HCBKGIIK_00206	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
HCBKGIIK_00207	3.41e-170	pduB	-	-	E	-	-	-	BMC
HCBKGIIK_00208	2.33e-50	-	-	-	CQ	-	-	-	BMC
HCBKGIIK_00209	1.69e-202	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HCBKGIIK_00210	4.02e-177	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
HCBKGIIK_00211	9.82e-173	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HCBKGIIK_00212	6.77e-204	-	-	-	-	-	-	-	-
HCBKGIIK_00213	8.07e-199	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HCBKGIIK_00214	1.69e-227	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HCBKGIIK_00215	7.13e-169	XK27_07210	-	-	S	-	-	-	B3 4 domain
HCBKGIIK_00216	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_00217	5.04e-116	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HCBKGIIK_00218	9.43e-116	-	-	-	GM	-	-	-	epimerase
HCBKGIIK_00219	7.72e-196	-	-	-	V	-	-	-	(ABC) transporter
HCBKGIIK_00220	6.23e-303	yhdP	-	-	S	-	-	-	Transporter associated domain
HCBKGIIK_00221	1.57e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HCBKGIIK_00222	4.3e-96	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HCBKGIIK_00223	7.93e-242	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HCBKGIIK_00224	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCBKGIIK_00225	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCBKGIIK_00226	1.02e-51	-	-	-	-	-	-	-	-
HCBKGIIK_00227	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HCBKGIIK_00228	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCBKGIIK_00229	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HCBKGIIK_00230	1.07e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCBKGIIK_00231	8.6e-222	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HCBKGIIK_00232	3.85e-298	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HCBKGIIK_00233	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCBKGIIK_00234	1.62e-126	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCBKGIIK_00235	2.16e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCBKGIIK_00236	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCBKGIIK_00237	2.26e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HCBKGIIK_00238	6.48e-154	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HCBKGIIK_00239	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HCBKGIIK_00240	1.99e-153	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBKGIIK_00241	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
HCBKGIIK_00242	5.37e-74	-	-	-	S	-	-	-	Small secreted protein
HCBKGIIK_00243	1.59e-14	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HCBKGIIK_00244	8.08e-76	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HCBKGIIK_00245	6.19e-16	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HCBKGIIK_00246	1.79e-18	-	2.1.1.72, 3.1.21.3	AA10,CBM73	M	ko:K01154,ko:K02014,ko:K03933,ko:K07316	-	ko00000,ko01000,ko02000,ko02048	domain protein
HCBKGIIK_00247	4.37e-23	-	-	-	S	-	-	-	YSIRK type signal peptide
HCBKGIIK_00248	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCBKGIIK_00249	1.9e-278	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HCBKGIIK_00250	5.44e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_00251	8.29e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HCBKGIIK_00253	4.08e-176	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCBKGIIK_00254	0.0	yhaN	-	-	L	-	-	-	AAA domain
HCBKGIIK_00255	2.34e-285	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HCBKGIIK_00256	2.42e-64	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HCBKGIIK_00257	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HCBKGIIK_00258	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HCBKGIIK_00259	2.51e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCBKGIIK_00260	2.15e-210	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCBKGIIK_00262	2.47e-53	-	-	-	-	-	-	-	-
HCBKGIIK_00263	1.88e-60	-	-	-	-	-	-	-	-
HCBKGIIK_00264	1.53e-266	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HCBKGIIK_00265	1.12e-131	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HCBKGIIK_00266	2.14e-280	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HCBKGIIK_00267	7.92e-135	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HCBKGIIK_00268	1.25e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HCBKGIIK_00269	3.38e-72	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCBKGIIK_00270	4.27e-89	-	-	-	-	-	-	-	-
HCBKGIIK_00272	9.17e-59	-	-	-	-	-	-	-	-
HCBKGIIK_00273	1.48e-149	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCBKGIIK_00274	1.78e-42	-	-	-	-	-	-	-	-
HCBKGIIK_00275	4.68e-207	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCBKGIIK_00276	3.58e-238	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HCBKGIIK_00277	1.53e-146	-	-	-	-	-	-	-	-
HCBKGIIK_00278	2.52e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HCBKGIIK_00279	4.49e-222	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCBKGIIK_00280	2.18e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCBKGIIK_00281	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HCBKGIIK_00282	8.34e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCBKGIIK_00283	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HCBKGIIK_00284	1.77e-56	-	-	-	-	-	-	-	-
HCBKGIIK_00285	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HCBKGIIK_00286	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCBKGIIK_00287	7.72e-122	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HCBKGIIK_00288	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_00289	1.46e-110	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HCBKGIIK_00290	2.01e-302	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HCBKGIIK_00291	1.13e-132	-	-	-	V	-	-	-	VanZ like family
HCBKGIIK_00292	7.03e-33	-	-	-	-	-	-	-	-
HCBKGIIK_00293	1.36e-99	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HCBKGIIK_00294	4.4e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCBKGIIK_00295	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HCBKGIIK_00296	1.55e-99	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HCBKGIIK_00297	2.14e-195	yeaE	-	-	S	-	-	-	Aldo keto
HCBKGIIK_00298	5.38e-308	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HCBKGIIK_00299	6.91e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HCBKGIIK_00300	5.48e-188	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HCBKGIIK_00301	1.46e-134	-	-	-	M	-	-	-	LysM domain protein
HCBKGIIK_00302	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HCBKGIIK_00303	5.35e-86	-	-	-	M	-	-	-	LysM domain protein
HCBKGIIK_00304	7.16e-201	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HCBKGIIK_00305	2.19e-141	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCBKGIIK_00306	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HCBKGIIK_00307	2.02e-306	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HCBKGIIK_00308	5.19e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCBKGIIK_00310	5.48e-58	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HCBKGIIK_00311	4.08e-107	-	-	-	-	-	-	-	-
HCBKGIIK_00312	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HCBKGIIK_00313	6.21e-241	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCBKGIIK_00314	9.26e-218	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCBKGIIK_00315	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCBKGIIK_00316	8.67e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HCBKGIIK_00317	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCBKGIIK_00318	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HCBKGIIK_00319	4.14e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HCBKGIIK_00320	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
HCBKGIIK_00321	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCBKGIIK_00322	1.13e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCBKGIIK_00323	3.29e-146	-	-	-	S	-	-	-	(CBS) domain
HCBKGIIK_00324	3.27e-185	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HCBKGIIK_00325	1.59e-308	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HCBKGIIK_00326	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HCBKGIIK_00327	5.31e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HCBKGIIK_00328	8.16e-265	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCBKGIIK_00329	8.96e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCBKGIIK_00330	4.54e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HCBKGIIK_00331	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBKGIIK_00332	1.1e-300	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HCBKGIIK_00333	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBKGIIK_00334	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCBKGIIK_00335	2.36e-67	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HCBKGIIK_00336	8.59e-130	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HCBKGIIK_00337	9.06e-195	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCBKGIIK_00338	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCBKGIIK_00339	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCBKGIIK_00340	3.7e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HCBKGIIK_00341	9.94e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HCBKGIIK_00342	5.7e-114	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCBKGIIK_00343	1.84e-155	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HCBKGIIK_00344	5.32e-208	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HCBKGIIK_00345	8.28e-177	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCBKGIIK_00346	5.24e-192	-	-	-	G	-	-	-	Right handed beta helix region
HCBKGIIK_00347	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HCBKGIIK_00348	4.8e-159	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HCBKGIIK_00349	7.58e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCBKGIIK_00350	1.46e-299	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBKGIIK_00351	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HCBKGIIK_00352	1.11e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCBKGIIK_00353	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCBKGIIK_00354	2.44e-84	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCBKGIIK_00355	3.15e-71	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HCBKGIIK_00356	4.49e-193	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HCBKGIIK_00357	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HCBKGIIK_00358	7.71e-189	yidA	-	-	S	-	-	-	hydrolase
HCBKGIIK_00359	1.19e-98	-	-	-	-	-	-	-	-
HCBKGIIK_00360	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCBKGIIK_00361	2.14e-312	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCBKGIIK_00362	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HCBKGIIK_00363	1.75e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HCBKGIIK_00364	1.98e-157	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HCBKGIIK_00365	1.93e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HCBKGIIK_00366	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCBKGIIK_00367	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HCBKGIIK_00368	1.03e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCBKGIIK_00369	4.08e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCBKGIIK_00370	3.58e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HCBKGIIK_00371	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCBKGIIK_00372	2.25e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HCBKGIIK_00374	2.31e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HCBKGIIK_00375	1.05e-225	-	-	-	-	-	-	-	-
HCBKGIIK_00376	9.64e-289	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HCBKGIIK_00377	3.08e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCBKGIIK_00378	2.26e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCBKGIIK_00379	1.51e-232	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HCBKGIIK_00380	5.68e-12	-	-	-	IQ	-	-	-	KR domain
HCBKGIIK_00381	1.1e-144	-	-	-	IQ	-	-	-	KR domain
HCBKGIIK_00382	1.47e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HCBKGIIK_00383	4.26e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HCBKGIIK_00384	1.1e-312	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_00385	8.34e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HCBKGIIK_00386	6.5e-71	-	-	-	-	-	-	-	-
HCBKGIIK_00387	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCBKGIIK_00388	2.59e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HCBKGIIK_00389	4.14e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HCBKGIIK_00390	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_00391	4.53e-203	-	-	-	-	-	-	-	-
HCBKGIIK_00392	9.72e-167	idhA	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKGIIK_00393	6.43e-214	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCBKGIIK_00394	1.4e-109	-	-	-	K	-	-	-	FCD
HCBKGIIK_00395	1.37e-213	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HCBKGIIK_00396	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HCBKGIIK_00397	5.64e-267	-	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_00398	2.76e-176	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HCBKGIIK_00399	2.61e-148	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HCBKGIIK_00400	2.31e-11	-	-	-	-	-	-	-	-
HCBKGIIK_00401	1.78e-83	-	-	-	-	-	-	-	-
HCBKGIIK_00402	2.02e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HCBKGIIK_00403	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HCBKGIIK_00404	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HCBKGIIK_00405	2.96e-211	-	-	-	GK	-	-	-	ROK family
HCBKGIIK_00406	2.45e-304	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCBKGIIK_00407	2.91e-176	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HCBKGIIK_00408	9.91e-102	-	-	-	E	-	-	-	amino acid
HCBKGIIK_00409	6.26e-143	-	-	-	E	-	-	-	amino acid
HCBKGIIK_00410	7.66e-23	-	-	-	E	-	-	-	amino acid
HCBKGIIK_00411	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HCBKGIIK_00412	8.56e-162	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HCBKGIIK_00413	1.85e-110	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCBKGIIK_00414	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCBKGIIK_00415	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HCBKGIIK_00416	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HCBKGIIK_00417	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_00418	1.64e-23	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
HCBKGIIK_00419	1.86e-227	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKGIIK_00420	3.85e-24	-	-	-	S	-	-	-	PFAM Archaeal ATPase
HCBKGIIK_00421	4.06e-103	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HCBKGIIK_00422	4.28e-66	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HCBKGIIK_00423	1.94e-21	-	-	-	EG	-	-	-	PFAM EamA-like transporter family
HCBKGIIK_00424	4.7e-21	-	-	-	EG	-	-	-	EamA-like transporter family
HCBKGIIK_00425	2.9e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HCBKGIIK_00426	2.12e-145	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HCBKGIIK_00427	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HCBKGIIK_00428	8.19e-100	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HCBKGIIK_00429	6.65e-158	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HCBKGIIK_00430	5.37e-137	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HCBKGIIK_00431	9.92e-78	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HCBKGIIK_00432	1.16e-199	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HCBKGIIK_00433	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HCBKGIIK_00434	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HCBKGIIK_00435	2.84e-42	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HCBKGIIK_00436	1.56e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HCBKGIIK_00437	2.36e-305	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HCBKGIIK_00438	7.46e-298	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCBKGIIK_00439	1.24e-103	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HCBKGIIK_00440	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HCBKGIIK_00441	1.18e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HCBKGIIK_00442	6.4e-204	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HCBKGIIK_00443	7.15e-148	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HCBKGIIK_00444	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
HCBKGIIK_00445	3.3e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HCBKGIIK_00446	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HCBKGIIK_00447	6.29e-191	-	-	-	O	-	-	-	Band 7 protein
HCBKGIIK_00448	2.85e-61	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HCBKGIIK_00449	1.22e-136	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HCBKGIIK_00450	2.76e-151	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCBKGIIK_00451	1.73e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HCBKGIIK_00452	2.61e-236	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HCBKGIIK_00453	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HCBKGIIK_00454	8.71e-164	-	-	-	L	-	-	-	Transposase
HCBKGIIK_00455	1.42e-152	-	-	-	L	-	-	-	Transposase
HCBKGIIK_00456	2.78e-118	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HCBKGIIK_00457	3.63e-247	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCBKGIIK_00458	3.24e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HCBKGIIK_00459	8.5e-218	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HCBKGIIK_00460	2.86e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HCBKGIIK_00461	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HCBKGIIK_00462	1.57e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HCBKGIIK_00463	7.96e-158	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HCBKGIIK_00464	2.32e-206	-	-	-	EG	-	-	-	EamA-like transporter family
HCBKGIIK_00465	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HCBKGIIK_00466	2.01e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCBKGIIK_00467	4.8e-130	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HCBKGIIK_00468	3.25e-72	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCBKGIIK_00469	3.97e-107	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HCBKGIIK_00470	5.93e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HCBKGIIK_00471	1.55e-91	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HCBKGIIK_00472	7.39e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HCBKGIIK_00473	1.26e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCBKGIIK_00474	3.24e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCBKGIIK_00475	5.29e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HCBKGIIK_00476	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HCBKGIIK_00477	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HCBKGIIK_00478	5.23e-204	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCBKGIIK_00479	3.45e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HCBKGIIK_00480	1.18e-120	-	-	-	-	-	-	-	-
HCBKGIIK_00481	2.4e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBKGIIK_00482	3.16e-197	gspA	-	-	M	-	-	-	family 8
HCBKGIIK_00483	5.06e-198	-	-	-	S	-	-	-	Alpha beta hydrolase
HCBKGIIK_00484	7.5e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCBKGIIK_00485	4.27e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HCBKGIIK_00486	1.02e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HCBKGIIK_00487	5.56e-214	yvgN	-	-	C	-	-	-	Aldo keto reductase
HCBKGIIK_00488	7.79e-204	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HCBKGIIK_00489	5.42e-105	-	-	-	C	-	-	-	Flavodoxin
HCBKGIIK_00490	7.71e-102	-	-	-	S	-	-	-	Cupin domain
HCBKGIIK_00491	3.87e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
HCBKGIIK_00492	1.18e-308	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HCBKGIIK_00493	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HCBKGIIK_00494	1.84e-316	yhdP	-	-	S	-	-	-	Transporter associated domain
HCBKGIIK_00495	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HCBKGIIK_00496	3.01e-185	-	-	-	S	-	-	-	DUF218 domain
HCBKGIIK_00497	2.79e-89	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCBKGIIK_00498	4.18e-75	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBKGIIK_00499	2.56e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBKGIIK_00500	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HCBKGIIK_00501	2.67e-154	-	-	-	S	-	-	-	SNARE associated Golgi protein
HCBKGIIK_00502	7.36e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HCBKGIIK_00503	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCBKGIIK_00505	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HCBKGIIK_00506	4.69e-200	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HCBKGIIK_00507	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBKGIIK_00508	8.32e-56	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HCBKGIIK_00509	2.26e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HCBKGIIK_00510	5.93e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HCBKGIIK_00511	6.43e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HCBKGIIK_00512	1.15e-25	-	-	-	-	-	-	-	-
HCBKGIIK_00513	8e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HCBKGIIK_00514	5.6e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HCBKGIIK_00515	1.37e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HCBKGIIK_00517	4.22e-41	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HCBKGIIK_00518	2.05e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCBKGIIK_00519	2.06e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCBKGIIK_00520	1.02e-146	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HCBKGIIK_00525	4.27e-48	-	-	-	L	-	-	-	Helix-turn-helix domain
HCBKGIIK_00526	5.75e-52	-	-	-	S	-	-	-	Cytochrome B5
HCBKGIIK_00527	6.32e-161	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_00528	3.7e-19	-	-	-	-	-	-	-	-
HCBKGIIK_00529	1.2e-264	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HCBKGIIK_00530	1.22e-102	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HCBKGIIK_00531	8.46e-07	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HCBKGIIK_00532	9.81e-36	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HCBKGIIK_00533	3.29e-104	-	-	-	-	-	-	-	-
HCBKGIIK_00534	7.18e-173	-	-	-	M	-	-	-	Lysin motif
HCBKGIIK_00535	1.21e-251	-	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_00536	2.74e-50	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HCBKGIIK_00537	3.4e-66	-	-	-	S	-	-	-	ParE toxin of type II toxin-antitoxin system, parDE
HCBKGIIK_00538	5.18e-114	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HCBKGIIK_00539	1.2e-205	-	-	-	J	-	-	-	Methyltransferase
HCBKGIIK_00540	5.16e-289	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HCBKGIIK_00541	1.5e-81	-	-	-	V	-	-	-	DNA restriction-modification system
HCBKGIIK_00542	9.02e-27	-	-	-	LV	-	-	-	TaqI-like C-terminal specificity domain
HCBKGIIK_00543	7.28e-59	-	-	-	V	-	-	-	DNA restriction-modification system
HCBKGIIK_00544	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HCBKGIIK_00545	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HCBKGIIK_00546	1.15e-207	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HCBKGIIK_00547	1.64e-233	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HCBKGIIK_00548	0.0	ade	-	-	F	-	-	-	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HCBKGIIK_00549	3.1e-95	-	-	-	L	-	-	-	Helix-turn-helix domain
HCBKGIIK_00550	4.43e-172	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HCBKGIIK_00551	2.95e-106	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HCBKGIIK_00553	4.63e-183	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCBKGIIK_00554	1.32e-36	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HCBKGIIK_00555	3.75e-163	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HCBKGIIK_00556	9.19e-261	-	-	-	L	-	-	-	Integrase core domain
HCBKGIIK_00557	2.68e-65	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HCBKGIIK_00558	2.81e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HCBKGIIK_00559	1.04e-248	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HCBKGIIK_00560	2e-181	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HCBKGIIK_00561	9.82e-69	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_00567	1.11e-149	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HCBKGIIK_00568	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HCBKGIIK_00569	1.69e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HCBKGIIK_00570	7.68e-151	-	-	-	I	-	-	-	phosphatase
HCBKGIIK_00571	8.68e-106	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HCBKGIIK_00572	5.75e-164	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCBKGIIK_00573	2.54e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HCBKGIIK_00574	3.16e-159	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HCBKGIIK_00575	1.58e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HCBKGIIK_00576	2.99e-151	-	-	-	S	-	-	-	membrane
HCBKGIIK_00577	7.81e-141	-	-	-	S	-	-	-	VIT family
HCBKGIIK_00578	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HCBKGIIK_00579	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_00580	5.46e-195	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCBKGIIK_00581	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCBKGIIK_00582	1.48e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCBKGIIK_00583	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HCBKGIIK_00584	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBKGIIK_00585	3.88e-73	-	-	-	-	-	-	-	-
HCBKGIIK_00586	3.09e-97	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HCBKGIIK_00587	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HCBKGIIK_00588	1.26e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HCBKGIIK_00589	1.84e-204	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCBKGIIK_00591	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCBKGIIK_00592	3.07e-119	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HCBKGIIK_00593	2.16e-238	-	-	-	I	-	-	-	Alpha beta
HCBKGIIK_00594	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_00595	1.91e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HCBKGIIK_00596	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HCBKGIIK_00597	2.81e-202	-	-	-	K	-	-	-	LysR family
HCBKGIIK_00598	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HCBKGIIK_00599	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HCBKGIIK_00600	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCBKGIIK_00601	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HCBKGIIK_00602	1.44e-202	mleR	-	-	K	-	-	-	LysR family
HCBKGIIK_00603	6.76e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCBKGIIK_00604	7.79e-263	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HCBKGIIK_00605	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HCBKGIIK_00606	6.38e-215	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HCBKGIIK_00607	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HCBKGIIK_00608	8.39e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCBKGIIK_00609	8.5e-287	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCBKGIIK_00610	2.47e-179	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HCBKGIIK_00611	1.48e-176	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCBKGIIK_00612	1.42e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCBKGIIK_00613	4.92e-168	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBKGIIK_00614	2.18e-246	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCBKGIIK_00615	9.73e-132	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HCBKGIIK_00616	7.34e-162	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HCBKGIIK_00617	5.54e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HCBKGIIK_00618	2.44e-217	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCBKGIIK_00619	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCBKGIIK_00620	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HCBKGIIK_00621	3.18e-133	pncA	-	-	Q	-	-	-	Isochorismatase family
HCBKGIIK_00622	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCBKGIIK_00623	8.85e-164	-	-	-	F	-	-	-	NUDIX domain
HCBKGIIK_00624	1.27e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCBKGIIK_00625	8.27e-235	-	-	-	S	-	-	-	Phage capsid family
HCBKGIIK_00626	1.34e-52	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HCBKGIIK_00627	5.85e-73	-	-	-	S	-	-	-	Phage head-tail joining protein
HCBKGIIK_00628	8.57e-71	-	-	-	S	-	-	-	Bacteriophage holin family
HCBKGIIK_00629	1.13e-26	-	-	-	-	-	-	-	-
HCBKGIIK_00630	9.73e-85	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HCBKGIIK_00631	3.23e-149	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HCBKGIIK_00632	2e-184	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HCBKGIIK_00633	2.78e-30	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HCBKGIIK_00634	4e-79	-	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Asp/Glu/Hydantoin racemase
HCBKGIIK_00635	1.9e-107	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HCBKGIIK_00636	7.04e-22	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HCBKGIIK_00637	5.87e-147	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HCBKGIIK_00638	2.47e-119	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HCBKGIIK_00639	3.19e-45	-	-	-	C	-	-	-	Heavy-metal-associated domain
HCBKGIIK_00640	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HCBKGIIK_00641	7.09e-157	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HCBKGIIK_00642	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HCBKGIIK_00643	2.81e-174	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HCBKGIIK_00644	2.32e-55	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCBKGIIK_00651	2.46e-36	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
HCBKGIIK_00652	7.15e-38	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HCBKGIIK_00653	9.83e-36	-	-	-	-	-	-	-	-
HCBKGIIK_00656	9.31e-59	-	-	-	-	-	-	-	-
HCBKGIIK_00657	2.25e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCBKGIIK_00664	5.34e-108	lytE	-	-	M	-	-	-	Lysin motif
HCBKGIIK_00665	3.16e-190	-	-	-	S	-	-	-	Cof-like hydrolase
HCBKGIIK_00666	6.2e-103	-	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_00667	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HCBKGIIK_00668	3e-69	-	-	-	-	-	-	-	-
HCBKGIIK_00669	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCBKGIIK_00670	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCBKGIIK_00671	5.7e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HCBKGIIK_00672	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCBKGIIK_00673	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HCBKGIIK_00674	1.01e-87	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCBKGIIK_00675	1.25e-211	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCBKGIIK_00676	2.76e-215	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HCBKGIIK_00677	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCBKGIIK_00678	1.19e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HCBKGIIK_00679	2.63e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCBKGIIK_00680	3.44e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HCBKGIIK_00681	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HCBKGIIK_00682	4.35e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCBKGIIK_00683	6.49e-135	-	-	-	-	-	-	-	-
HCBKGIIK_00684	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCBKGIIK_00685	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCBKGIIK_00686	5.57e-167	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HCBKGIIK_00687	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HCBKGIIK_00688	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HCBKGIIK_00689	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HCBKGIIK_00690	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCBKGIIK_00691	1.45e-181	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCBKGIIK_00692	4.41e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HCBKGIIK_00693	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCBKGIIK_00695	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCBKGIIK_00696	4.97e-131	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_00697	1.83e-21	-	-	-	-	-	-	-	-
HCBKGIIK_00699	1.59e-217	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HCBKGIIK_00700	9.5e-238	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HCBKGIIK_00701	1.63e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HCBKGIIK_00702	4.5e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HCBKGIIK_00703	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCBKGIIK_00704	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCBKGIIK_00705	1.03e-19	-	-	-	-	-	-	-	-
HCBKGIIK_00706	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HCBKGIIK_00707	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCBKGIIK_00708	9.93e-115	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HCBKGIIK_00709	4.9e-207	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HCBKGIIK_00710	1.75e-257	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HCBKGIIK_00711	1.37e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCBKGIIK_00712	3.22e-214	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HCBKGIIK_00713	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HCBKGIIK_00714	8.71e-176	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HCBKGIIK_00715	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HCBKGIIK_00716	9.42e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HCBKGIIK_00717	9.5e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCBKGIIK_00718	3.96e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCBKGIIK_00719	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HCBKGIIK_00720	4.27e-66	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HCBKGIIK_00721	1.58e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCBKGIIK_00722	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCBKGIIK_00723	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCBKGIIK_00724	2.24e-143	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HCBKGIIK_00725	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HCBKGIIK_00726	1.44e-139	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HCBKGIIK_00727	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCBKGIIK_00728	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HCBKGIIK_00729	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HCBKGIIK_00730	1.19e-25	-	-	-	-	-	-	-	-
HCBKGIIK_00731	6.59e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCBKGIIK_00732	1.1e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HCBKGIIK_00733	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HCBKGIIK_00734	1.02e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCBKGIIK_00735	5.71e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HCBKGIIK_00736	5.21e-155	-	-	-	S	-	-	-	repeat protein
HCBKGIIK_00737	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCBKGIIK_00738	3.49e-222	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCBKGIIK_00739	2.6e-233	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCBKGIIK_00740	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HCBKGIIK_00741	9.35e-311	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCBKGIIK_00742	4.39e-110	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCBKGIIK_00743	2.32e-283	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCBKGIIK_00744	1.32e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCBKGIIK_00745	1.56e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCBKGIIK_00746	5.91e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCBKGIIK_00747	4.47e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCBKGIIK_00748	5.77e-104	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HCBKGIIK_00749	1.1e-279	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HCBKGIIK_00750	3.74e-265	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HCBKGIIK_00751	2.15e-75	-	-	-	-	-	-	-	-
HCBKGIIK_00753	2.51e-217	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HCBKGIIK_00754	4.37e-39	-	-	-	-	-	-	-	-
HCBKGIIK_00755	7.16e-231	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HCBKGIIK_00756	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HCBKGIIK_00757	3.66e-103	-	-	-	-	-	-	-	-
HCBKGIIK_00758	2.78e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCBKGIIK_00759	6.71e-265	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HCBKGIIK_00760	1.34e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HCBKGIIK_00761	1.23e-310	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCBKGIIK_00762	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HCBKGIIK_00763	1.32e-59	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HCBKGIIK_00764	4.59e-173	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HCBKGIIK_00765	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HCBKGIIK_00766	1.52e-283	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HCBKGIIK_00767	6.37e-60	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HCBKGIIK_00768	4.59e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HCBKGIIK_00769	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCBKGIIK_00770	2.03e-250	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HCBKGIIK_00771	4.83e-138	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HCBKGIIK_00772	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HCBKGIIK_00773	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HCBKGIIK_00774	2.27e-200	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HCBKGIIK_00775	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HCBKGIIK_00776	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCBKGIIK_00777	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBKGIIK_00778	3.07e-209	-	-	-	S	-	-	-	Tetratricopeptide repeat
HCBKGIIK_00779	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCBKGIIK_00780	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCBKGIIK_00781	4.15e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCBKGIIK_00782	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HCBKGIIK_00783	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HCBKGIIK_00784	2.44e-20	-	-	-	-	-	-	-	-
HCBKGIIK_00785	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCBKGIIK_00786	9.78e-314	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCBKGIIK_00787	2.79e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCBKGIIK_00788	2.9e-199	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBKGIIK_00789	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HCBKGIIK_00790	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCBKGIIK_00791	8.86e-122	-	-	-	-	-	-	-	-
HCBKGIIK_00792	1.6e-172	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCBKGIIK_00793	2.2e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HCBKGIIK_00794	9.62e-41	-	-	-	-	-	-	-	-
HCBKGIIK_00795	1.41e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HCBKGIIK_00796	4.38e-23	-	-	-	S	-	-	-	Helix-turn-helix domain
HCBKGIIK_00798	5.17e-57	-	-	-	K	-	-	-	COG3617 Prophage antirepressor
HCBKGIIK_00806	5.79e-88	-	-	-	-	-	-	-	-
HCBKGIIK_00807	8.58e-73	-	-	-	-	-	-	-	-
HCBKGIIK_00810	1.09e-26	-	-	-	S	-	-	-	exonuclease activity
HCBKGIIK_00811	8.76e-75	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
HCBKGIIK_00813	1.9e-21	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCBKGIIK_00814	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HCBKGIIK_00816	5.67e-278	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HCBKGIIK_00817	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HCBKGIIK_00818	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCBKGIIK_00819	3.42e-200	-	-	-	EG	-	-	-	EamA-like transporter family
HCBKGIIK_00820	3.89e-49	-	-	-	Q	-	-	-	pyridine nucleotide-disulphide oxidoreductase
HCBKGIIK_00821	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HCBKGIIK_00822	1.9e-147	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HCBKGIIK_00823	6.69e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HCBKGIIK_00824	7.69e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCBKGIIK_00825	3.69e-45	-	-	-	S	-	-	-	Transglycosylase associated protein
HCBKGIIK_00826	6.47e-10	-	-	-	S	-	-	-	CsbD-like
HCBKGIIK_00827	1.56e-229	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKGIIK_00828	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HCBKGIIK_00829	1.44e-121	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HCBKGIIK_00830	1.23e-52	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HCBKGIIK_00831	3.82e-192	-	-	-	-	-	-	-	-
HCBKGIIK_00832	1.01e-29	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HCBKGIIK_00833	2.03e-105	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HCBKGIIK_00834	1.26e-130	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HCBKGIIK_00835	3.46e-95	-	-	-	F	-	-	-	Nudix hydrolase
HCBKGIIK_00836	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HCBKGIIK_00837	1.69e-296	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HCBKGIIK_00838	4.51e-148	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_00839	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCBKGIIK_00840	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCBKGIIK_00841	7.1e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HCBKGIIK_00842	2.37e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCBKGIIK_00843	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCBKGIIK_00844	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HCBKGIIK_00845	5.45e-233	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HCBKGIIK_00846	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCBKGIIK_00847	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HCBKGIIK_00848	1.81e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HCBKGIIK_00849	9.28e-307	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HCBKGIIK_00850	4.2e-157	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HCBKGIIK_00851	8.33e-230	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HCBKGIIK_00852	3.82e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HCBKGIIK_00853	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HCBKGIIK_00854	4.45e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HCBKGIIK_00855	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_00856	3.32e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HCBKGIIK_00857	1.87e-288	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HCBKGIIK_00858	1.92e-316	ymfH	-	-	S	-	-	-	Peptidase M16
HCBKGIIK_00859	4.4e-192	-	-	-	S	-	-	-	Helix-turn-helix domain
HCBKGIIK_00860	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCBKGIIK_00861	1.08e-287	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HCBKGIIK_00862	2.2e-251	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCBKGIIK_00863	4.62e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HCBKGIIK_00864	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCBKGIIK_00865	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCBKGIIK_00866	4.34e-131	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCBKGIIK_00867	2.74e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCBKGIIK_00868	9.79e-239	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCBKGIIK_00869	1.44e-59	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HCBKGIIK_00870	3.56e-233	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HCBKGIIK_00871	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCBKGIIK_00872	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCBKGIIK_00873	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HCBKGIIK_00874	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCBKGIIK_00875	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HCBKGIIK_00876	1.44e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
HCBKGIIK_00877	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCBKGIIK_00878	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HCBKGIIK_00879	5.82e-124	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HCBKGIIK_00880	6.89e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HCBKGIIK_00881	4.22e-136	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCBKGIIK_00882	1.65e-120	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HCBKGIIK_00883	8.55e-99	ykuL	-	-	S	-	-	-	(CBS) domain
HCBKGIIK_00884	2.57e-72	isp	-	-	L	-	-	-	Transposase
HCBKGIIK_00885	5.67e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HCBKGIIK_00886	9.33e-229	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCBKGIIK_00887	1.13e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HCBKGIIK_00888	1.8e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HCBKGIIK_00889	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCBKGIIK_00890	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HCBKGIIK_00891	5.62e-37	-	-	-	-	-	-	-	-
HCBKGIIK_00892	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HCBKGIIK_00893	1.82e-129	-	-	-	S	-	-	-	Pfam:DUF3816
HCBKGIIK_00894	3.86e-182	-	-	-	G	-	-	-	MucBP domain
HCBKGIIK_00895	7.04e-149	-	-	-	-	-	-	-	-
HCBKGIIK_00896	3.55e-199	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_00897	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HCBKGIIK_00898	0.0	-	-	-	S	-	-	-	Peptidase, M23
HCBKGIIK_00899	0.0	-	-	-	M	-	-	-	NlpC/P60 family
HCBKGIIK_00900	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCBKGIIK_00901	6.84e-301	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HCBKGIIK_00902	3.74e-232	yueF	-	-	S	-	-	-	AI-2E family transporter
HCBKGIIK_00903	0.0	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HCBKGIIK_00904	6.42e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCBKGIIK_00905	1.34e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCBKGIIK_00906	7.93e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HCBKGIIK_00907	1.58e-205	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCBKGIIK_00908	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCBKGIIK_00909	1.74e-173	-	-	-	-	-	-	-	-
HCBKGIIK_00910	4.52e-184	-	-	-	M	-	-	-	Glycosyl transferase family 2
HCBKGIIK_00911	2.96e-95	-	-	-	-	-	-	-	-
HCBKGIIK_00912	1.14e-89	-	-	-	S	-	-	-	Acyltransferase family
HCBKGIIK_00913	4.04e-97	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
HCBKGIIK_00914	1.1e-84	-	-	-	S	-	-	-	Glycosyltransferase like family
HCBKGIIK_00915	3.13e-95	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HCBKGIIK_00916	2.42e-38	-	-	-	M	-	-	-	biosynthesis protein
HCBKGIIK_00917	8.66e-108	-	-	-	-	-	-	-	-
HCBKGIIK_00918	1.51e-95	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HCBKGIIK_00919	8.05e-264	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HCBKGIIK_00920	1.23e-278	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HCBKGIIK_00921	3.83e-39	-	-	-	-	-	-	-	-
HCBKGIIK_00922	0.0	-	-	-	G	-	-	-	Peptidase_C39 like family
HCBKGIIK_00923	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HCBKGIIK_00924	4.01e-153	-	-	-	M	-	-	-	Bacterial sugar transferase
HCBKGIIK_00925	5.18e-221	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HCBKGIIK_00926	2.23e-188	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HCBKGIIK_00927	4.55e-172	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HCBKGIIK_00928	8.83e-43	-	-	-	-	-	-	-	-
HCBKGIIK_00929	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HCBKGIIK_00930	3.38e-195	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HCBKGIIK_00931	0.0	potE	-	-	E	-	-	-	Amino Acid
HCBKGIIK_00932	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HCBKGIIK_00933	1.97e-280	arcT	-	-	E	-	-	-	Aminotransferase
HCBKGIIK_00934	4.08e-215	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HCBKGIIK_00935	9.49e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HCBKGIIK_00936	2.45e-88	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HCBKGIIK_00937	3.98e-15	-	-	-	-	-	-	-	-
HCBKGIIK_00938	2.09e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCBKGIIK_00940	4.69e-298	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HCBKGIIK_00941	1.08e-244	mocA	-	-	S	-	-	-	Oxidoreductase
HCBKGIIK_00942	4.62e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HCBKGIIK_00943	2.95e-135	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HCBKGIIK_00944	1.86e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCBKGIIK_00945	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HCBKGIIK_00946	1.6e-246	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HCBKGIIK_00947	4.36e-103	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HCBKGIIK_00948	2.64e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HCBKGIIK_00949	3.86e-95	-	-	-	P	-	-	-	Major Facilitator Superfamily
HCBKGIIK_00950	1.21e-26	-	-	-	-	-	-	-	-
HCBKGIIK_00951	1.46e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HCBKGIIK_00952	2.03e-100	-	-	-	K	-	-	-	LytTr DNA-binding domain
HCBKGIIK_00953	2.62e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HCBKGIIK_00954	3.35e-216	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HCBKGIIK_00955	1.52e-108	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HCBKGIIK_00956	7.82e-161	pnb	-	-	C	-	-	-	nitroreductase
HCBKGIIK_00957	7.41e-120	-	-	-	-	-	-	-	-
HCBKGIIK_00958	5.61e-108	yvbK	-	-	K	-	-	-	GNAT family
HCBKGIIK_00959	3.55e-313	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HCBKGIIK_00960	2.44e-266	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HCBKGIIK_00961	2.16e-80	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HCBKGIIK_00962	1.75e-94	-	-	-	-	-	-	-	-
HCBKGIIK_00963	2.76e-221	-	-	-	-	-	-	-	-
HCBKGIIK_00964	1.04e-226	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HCBKGIIK_00965	2.02e-172	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCBKGIIK_00966	1.77e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCBKGIIK_00967	7.28e-101	-	-	-	S	-	-	-	Flavodoxin
HCBKGIIK_00968	1.81e-81	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HCBKGIIK_00969	5.33e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HCBKGIIK_00970	3.04e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HCBKGIIK_00971	1.9e-203	-	-	-	H	-	-	-	geranyltranstransferase activity
HCBKGIIK_00972	9.33e-226	-	-	-	-	-	-	-	-
HCBKGIIK_00973	1.54e-26	-	-	-	-	-	-	-	-
HCBKGIIK_00974	2.22e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HCBKGIIK_00975	3.07e-241	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HCBKGIIK_00976	5.25e-59	-	-	-	-	-	-	-	-
HCBKGIIK_00977	4.55e-124	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HCBKGIIK_00978	2.25e-97	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HCBKGIIK_00979	3.34e-286	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HCBKGIIK_00980	1.65e-107	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HCBKGIIK_00981	4.32e-235	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HCBKGIIK_00982	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HCBKGIIK_00983	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HCBKGIIK_00984	3.47e-129	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HCBKGIIK_00985	3.85e-167	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HCBKGIIK_00986	9.33e-197	-	-	-	EG	-	-	-	EamA-like transporter family
HCBKGIIK_00987	9.45e-152	-	-	-	L	-	-	-	Integrase
HCBKGIIK_00988	1.15e-200	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HCBKGIIK_00989	3.63e-120	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HCBKGIIK_00990	3.16e-111	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
HCBKGIIK_00991	2.12e-254	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCBKGIIK_00993	1.39e-91	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCBKGIIK_00994	1.94e-100	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HCBKGIIK_00995	1.12e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCBKGIIK_00996	1.99e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCBKGIIK_00997	4.93e-197	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HCBKGIIK_00998	2.76e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HCBKGIIK_00999	5.28e-281	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCBKGIIK_01000	4.19e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCBKGIIK_01001	2.29e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCBKGIIK_01002	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HCBKGIIK_01003	1.45e-184	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCBKGIIK_01004	3.64e-175	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HCBKGIIK_01005	1.12e-167	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HCBKGIIK_01011	1.94e-147	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HCBKGIIK_01012	5.45e-31	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HCBKGIIK_01013	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HCBKGIIK_01014	3.78e-219	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HCBKGIIK_01015	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HCBKGIIK_01017	5.1e-89	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HCBKGIIK_01018	2.74e-50	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HCBKGIIK_01020	0.0	snf	-	-	KL	-	-	-	domain protein
HCBKGIIK_01021	1.97e-183	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HCBKGIIK_01022	3.9e-266	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCBKGIIK_01023	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HCBKGIIK_01024	4.61e-133	-	-	-	L	-	-	-	nuclease
HCBKGIIK_01025	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HCBKGIIK_01026	1.5e-91	-	-	-	-	-	-	-	-
HCBKGIIK_01027	1.95e-131	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HCBKGIIK_01028	9.68e-159	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCBKGIIK_01029	1.29e-194	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HCBKGIIK_01030	1.29e-37	-	-	-	-	-	-	-	-
HCBKGIIK_01031	3.47e-196	-	-	-	-	-	-	-	-
HCBKGIIK_01033	2.21e-87	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HCBKGIIK_01035	6.51e-132	-	-	-	L	-	-	-	Integrase core domain
HCBKGIIK_01036	2.03e-141	-	-	-	L	-	-	-	Bacterial dnaA protein
HCBKGIIK_01040	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HCBKGIIK_01041	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCBKGIIK_01042	1.63e-81	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCBKGIIK_01043	2.52e-68	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCBKGIIK_01044	4.05e-107	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCBKGIIK_01045	4.84e-267	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HCBKGIIK_01046	7.01e-78	-	-	-	S	-	-	-	FRG
HCBKGIIK_01047	6.01e-122	-	-	-	S	-	-	-	FRG
HCBKGIIK_01048	3.73e-81	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HCBKGIIK_01049	7.47e-123	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HCBKGIIK_01050	7.72e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HCBKGIIK_01051	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HCBKGIIK_01052	4.52e-154	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCBKGIIK_01053	4.71e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HCBKGIIK_01054	1.9e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCBKGIIK_01055	5.88e-175	yqeM	-	-	Q	-	-	-	Methyltransferase
HCBKGIIK_01056	8.54e-268	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HCBKGIIK_01057	8.29e-129	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HCBKGIIK_01058	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HCBKGIIK_01059	9.72e-156	csrR	-	-	K	-	-	-	response regulator
HCBKGIIK_01060	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HCBKGIIK_01061	0.0	potE	-	-	E	-	-	-	Amino Acid
HCBKGIIK_01062	1.24e-296	-	-	-	V	-	-	-	MatE
HCBKGIIK_01063	1.52e-89	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCBKGIIK_01064	6.44e-214	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBKGIIK_01065	2.36e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HCBKGIIK_01066	2.71e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBKGIIK_01067	7.57e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBKGIIK_01068	5.79e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCBKGIIK_01069	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCBKGIIK_01070	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBKGIIK_01071	3.43e-148	-	-	-	M	-	-	-	PFAM NLP P60 protein
HCBKGIIK_01072	2.8e-150	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HCBKGIIK_01073	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCBKGIIK_01074	2.49e-87	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HCBKGIIK_01075	0.0	-	-	-	S	-	-	-	membrane
HCBKGIIK_01076	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HCBKGIIK_01077	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HCBKGIIK_01078	1.38e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCBKGIIK_01079	6.64e-78	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HCBKGIIK_01080	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HCBKGIIK_01081	1.02e-234	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HCBKGIIK_01082	1.09e-87	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HCBKGIIK_01083	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HCBKGIIK_01084	5.62e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCBKGIIK_01085	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HCBKGIIK_01086	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCBKGIIK_01087	3.18e-122	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCBKGIIK_01088	2.07e-40	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCBKGIIK_01089	1.7e-50	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCBKGIIK_01090	1.28e-18	-	-	-	-	-	-	-	-
HCBKGIIK_01091	2.72e-129	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCBKGIIK_01092	1.08e-67	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HCBKGIIK_01093	1.39e-202	-	-	-	-	-	-	-	-
HCBKGIIK_01094	1.95e-228	-	-	-	-	-	-	-	-
HCBKGIIK_01095	4.54e-111	-	-	-	S	-	-	-	Protein conserved in bacteria
HCBKGIIK_01099	9.45e-145	-	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_01100	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HCBKGIIK_01101	8.44e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HCBKGIIK_01102	5.93e-60	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HCBKGIIK_01103	7.44e-168	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCBKGIIK_01104	4.3e-256	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HCBKGIIK_01105	1.22e-147	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HCBKGIIK_01106	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HCBKGIIK_01107	1.84e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCBKGIIK_01108	1.88e-191	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCBKGIIK_01109	3.95e-280	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBKGIIK_01110	1.15e-57	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBKGIIK_01111	2.49e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCBKGIIK_01112	2.81e-191	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HCBKGIIK_01113	1.07e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCBKGIIK_01114	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HCBKGIIK_01115	8.66e-70	-	-	-	-	-	-	-	-
HCBKGIIK_01116	2.08e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HCBKGIIK_01117	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCBKGIIK_01118	3.56e-263	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCBKGIIK_01119	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCBKGIIK_01120	7.08e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCBKGIIK_01121	1.85e-316	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCBKGIIK_01122	1.17e-165	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HCBKGIIK_01123	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HCBKGIIK_01124	4.03e-207	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCBKGIIK_01125	1.06e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HCBKGIIK_01126	4.7e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HCBKGIIK_01127	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HCBKGIIK_01128	2.03e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HCBKGIIK_01129	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HCBKGIIK_01130	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCBKGIIK_01131	4.72e-241	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCBKGIIK_01132	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCBKGIIK_01133	6.38e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCBKGIIK_01134	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HCBKGIIK_01135	3.16e-261	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCBKGIIK_01136	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCBKGIIK_01137	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCBKGIIK_01138	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HCBKGIIK_01139	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HCBKGIIK_01140	5.33e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCBKGIIK_01141	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HCBKGIIK_01142	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HCBKGIIK_01143	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCBKGIIK_01144	1.05e-45	-	-	-	-	-	-	-	-
HCBKGIIK_01145	8.66e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HCBKGIIK_01146	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HCBKGIIK_01147	6.28e-19	-	-	-	-	-	-	-	-
HCBKGIIK_01148	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HCBKGIIK_01149	1.66e-246	flp	-	-	V	-	-	-	Beta-lactamase
HCBKGIIK_01150	3.54e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HCBKGIIK_01151	1.64e-84	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HCBKGIIK_01152	4.17e-69	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HCBKGIIK_01153	2.37e-162	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HCBKGIIK_01154	1.66e-235	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HCBKGIIK_01155	5.52e-116	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCBKGIIK_01156	2.57e-141	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HCBKGIIK_01157	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HCBKGIIK_01158	4.42e-153	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HCBKGIIK_01159	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
HCBKGIIK_01160	4.35e-239	-	-	-	S	-	-	-	amidohydrolase
HCBKGIIK_01164	8.73e-28	-	-	-	-	-	-	-	-
HCBKGIIK_01167	5.6e-56	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HCBKGIIK_01168	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01169	1.24e-125	epsB	-	-	M	-	-	-	biosynthesis protein
HCBKGIIK_01170	1.73e-137	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HCBKGIIK_01171	1.17e-62	-	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HCBKGIIK_01172	1.22e-103	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
HCBKGIIK_01173	4.15e-82	wefC	-	-	M	-	-	-	Stealth protein CR2, conserved region 2
HCBKGIIK_01174	7.26e-51	-	-	-	M	-	-	-	Glycosyltransferase GT-D fold
HCBKGIIK_01176	2.17e-84	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HCBKGIIK_01177	4.27e-49	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HCBKGIIK_01178	1.84e-34	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCBKGIIK_01179	3.85e-33	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HCBKGIIK_01180	1e-59	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HCBKGIIK_01182	1.86e-34	-	-	-	S	-	-	-	Acyltransferase family
HCBKGIIK_01183	0.0	-	2.4.1.5	GH13	G	ko:K00689	ko00500,ko02020,map00500,map02020	ko00000,ko00001,ko01000	Glycosyl hydrolase family 70
HCBKGIIK_01184	2.1e-94	-	-	-	-	-	-	-	-
HCBKGIIK_01185	2.79e-294	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCBKGIIK_01186	2.77e-178	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HCBKGIIK_01187	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HCBKGIIK_01188	2.21e-275	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HCBKGIIK_01189	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HCBKGIIK_01190	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HCBKGIIK_01191	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HCBKGIIK_01192	7.42e-118	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HCBKGIIK_01193	8.09e-207	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HCBKGIIK_01194	1.02e-171	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCBKGIIK_01195	4.8e-229	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HCBKGIIK_01196	8.7e-123	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HCBKGIIK_01197	4.21e-213	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HCBKGIIK_01198	1.28e-226	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HCBKGIIK_01199	2.2e-292	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCBKGIIK_01200	3.1e-113	-	-	-	Q	-	-	-	Methyltransferase
HCBKGIIK_01201	4.64e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HCBKGIIK_01202	1.37e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HCBKGIIK_01203	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HCBKGIIK_01204	3.28e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HCBKGIIK_01205	2.94e-285	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HCBKGIIK_01206	3.81e-52	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HCBKGIIK_01207	1.2e-237	-	-	-	M	-	-	-	Glycosyl transferase
HCBKGIIK_01208	3.28e-197	-	-	-	-	-	-	-	-
HCBKGIIK_01209	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HCBKGIIK_01210	9.02e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCBKGIIK_01211	4.47e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HCBKGIIK_01212	1.26e-191	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HCBKGIIK_01213	1.99e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HCBKGIIK_01214	2.58e-164	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HCBKGIIK_01216	1.64e-238	-	-	-	-	-	-	-	-
HCBKGIIK_01217	1.91e-125	-	-	-	K	-	-	-	acetyltransferase
HCBKGIIK_01218	2.76e-67	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HCBKGIIK_01219	1.56e-41	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HCBKGIIK_01220	1.59e-87	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HCBKGIIK_01221	1.58e-79	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCBKGIIK_01222	3.57e-238	-	-	-	-	-	-	-	-
HCBKGIIK_01223	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCBKGIIK_01224	1.26e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HCBKGIIK_01225	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HCBKGIIK_01227	1.84e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HCBKGIIK_01228	9.38e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCBKGIIK_01229	5.86e-157	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HCBKGIIK_01230	9.42e-41	-	-	-	L	-	-	-	Helix-turn-helix domain
HCBKGIIK_01231	2.19e-134	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HCBKGIIK_01232	1.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCBKGIIK_01233	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HCBKGIIK_01234	4.92e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCBKGIIK_01235	1.89e-227	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HCBKGIIK_01236	4.49e-186	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HCBKGIIK_01237	9.21e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HCBKGIIK_01238	1.21e-48	-	-	-	-	-	-	-	-
HCBKGIIK_01239	1.76e-68	-	-	-	-	-	-	-	-
HCBKGIIK_01240	4.14e-257	-	-	-	-	-	-	-	-
HCBKGIIK_01241	1.59e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCBKGIIK_01242	2.68e-173	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HCBKGIIK_01243	3.44e-200	yvgN	-	-	S	-	-	-	Aldo keto reductase
HCBKGIIK_01244	2.51e-160	XK27_10500	-	-	K	-	-	-	response regulator
HCBKGIIK_01245	1.19e-230	kinG	-	-	T	-	-	-	Histidine kinase-like ATPases
HCBKGIIK_01246	1.38e-171	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01247	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HCBKGIIK_01248	3.31e-200	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HCBKGIIK_01249	7.55e-213	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HCBKGIIK_01250	7.86e-13	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HCBKGIIK_01251	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBKGIIK_01252	1.16e-249	-	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_01253	2.55e-114	ymdB	-	-	S	-	-	-	Macro domain protein
HCBKGIIK_01254	1.51e-137	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCBKGIIK_01255	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HCBKGIIK_01256	8.55e-64	-	-	-	-	-	-	-	-
HCBKGIIK_01257	2.5e-296	-	-	-	S	-	-	-	Putative metallopeptidase domain
HCBKGIIK_01258	1.2e-260	-	-	-	S	-	-	-	associated with various cellular activities
HCBKGIIK_01259	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HCBKGIIK_01260	2.01e-84	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HCBKGIIK_01262	1.43e-152	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HCBKGIIK_01263	9.17e-70	-	-	-	-	-	-	-	-
HCBKGIIK_01265	4.23e-41	-	2.1.1.72	-	D	ko:K03427	-	ko00000,ko01000,ko02048	peptidase
HCBKGIIK_01266	8.04e-63	-	-	-	-	-	-	-	-
HCBKGIIK_01267	1.07e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HCBKGIIK_01268	3.36e-289	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HCBKGIIK_01269	7.21e-316	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HCBKGIIK_01270	2.85e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HCBKGIIK_01271	3.82e-182	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HCBKGIIK_01272	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HCBKGIIK_01273	4.15e-23	-	-	-	K	-	-	-	Helix-turn-helix domain
HCBKGIIK_01274	1.17e-56	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HCBKGIIK_01275	1.47e-81	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCBKGIIK_01276	1.73e-56	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HCBKGIIK_01277	1.78e-232	arsB	-	-	P	ko:K03325	-	ko00000,ko02000	Sodium Bile acid symporter family
HCBKGIIK_01278	1.31e-93	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCBKGIIK_01279	3.57e-74	cadX	-	-	K	ko:K21903	-	ko00000,ko03000	Bacterial regulatory protein, arsR family
HCBKGIIK_01280	3.39e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HCBKGIIK_01281	2.7e-18	XK27_09155	-	-	K	-	-	-	Transcriptional
HCBKGIIK_01282	3.81e-32	-	-	-	L	-	-	-	Integrase
HCBKGIIK_01283	1.36e-205	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01284	5.51e-49	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01288	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HCBKGIIK_01289	1.68e-100	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCBKGIIK_01290	1.76e-79	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCBKGIIK_01293	2.68e-144	-	-	-	-	-	-	-	-
HCBKGIIK_01294	3.57e-316	-	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_01295	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HCBKGIIK_01296	3.53e-168	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HCBKGIIK_01297	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HCBKGIIK_01298	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCBKGIIK_01299	1.02e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCBKGIIK_01300	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HCBKGIIK_01301	6.46e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HCBKGIIK_01303	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HCBKGIIK_01304	1.57e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HCBKGIIK_01305	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HCBKGIIK_01306	2.92e-170	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCBKGIIK_01307	8.91e-216	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HCBKGIIK_01308	1.74e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HCBKGIIK_01309	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCBKGIIK_01310	1.01e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01311	1.95e-177	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HCBKGIIK_01312	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HCBKGIIK_01313	5.89e-161	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCBKGIIK_01314	4.73e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HCBKGIIK_01315	4.86e-129	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HCBKGIIK_01316	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCBKGIIK_01317	5.49e-262	yacL	-	-	S	-	-	-	domain protein
HCBKGIIK_01318	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HCBKGIIK_01319	2.95e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCBKGIIK_01320	7.41e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBKGIIK_01321	8.88e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HCBKGIIK_01322	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCBKGIIK_01323	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HCBKGIIK_01324	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCBKGIIK_01325	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCBKGIIK_01326	2.96e-285	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HCBKGIIK_01328	1.15e-40	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HCBKGIIK_01329	1.41e-38	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HCBKGIIK_01330	1.11e-102	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HCBKGIIK_01331	1.53e-268	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCBKGIIK_01332	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCBKGIIK_01333	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCBKGIIK_01334	3.05e-49	-	-	-	-	-	-	-	-
HCBKGIIK_01335	3.29e-62	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCBKGIIK_01336	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HCBKGIIK_01337	6.31e-126	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HCBKGIIK_01338	1.13e-170	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HCBKGIIK_01339	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HCBKGIIK_01340	7.68e-254	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBKGIIK_01341	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBKGIIK_01342	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HCBKGIIK_01343	1.16e-114	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCBKGIIK_01344	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBKGIIK_01345	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCBKGIIK_01346	1.65e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCBKGIIK_01347	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HCBKGIIK_01348	1.97e-143	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCBKGIIK_01349	1.64e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HCBKGIIK_01350	7.16e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HCBKGIIK_01351	1.77e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HCBKGIIK_01352	4.31e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCBKGIIK_01353	1.18e-173	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HCBKGIIK_01354	3.89e-121	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCBKGIIK_01355	1.44e-140	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01359	3.65e-255	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HCBKGIIK_01361	3.96e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HCBKGIIK_01362	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HCBKGIIK_01364	6.98e-137	-	-	-	L	-	-	-	Helix-turn-helix domain
HCBKGIIK_01365	5.09e-91	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCBKGIIK_01366	1.23e-253	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HCBKGIIK_01367	2.33e-29	-	-	-	-	-	-	-	-
HCBKGIIK_01368	4.16e-29	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HCBKGIIK_01369	1.07e-138	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HCBKGIIK_01370	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HCBKGIIK_01371	1.1e-35	-	-	-	-	-	-	-	-
HCBKGIIK_01373	3.42e-41	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HCBKGIIK_01374	1.06e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HCBKGIIK_01375	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCBKGIIK_01376	3.94e-221	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HCBKGIIK_01377	3.71e-205	-	-	-	EG	-	-	-	EamA-like transporter family
HCBKGIIK_01378	1.17e-132	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HCBKGIIK_01379	1.26e-79	-	-	-	S	-	-	-	Cupredoxin-like domain
HCBKGIIK_01380	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HCBKGIIK_01381	6.11e-111	-	-	-	-	-	-	-	-
HCBKGIIK_01383	1.5e-74	-	-	-	-	-	-	-	-
HCBKGIIK_01384	3.53e-49	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCBKGIIK_01385	2.33e-146	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCBKGIIK_01386	1.18e-57	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HCBKGIIK_01388	4.73e-137	-	-	-	-	-	-	-	-
HCBKGIIK_01389	6.45e-160	-	-	-	M	-	-	-	domain protein
HCBKGIIK_01390	8.79e-176	-	-	-	M	-	-	-	domain protein
HCBKGIIK_01391	5.51e-147	-	-	-	M	-	-	-	domain protein
HCBKGIIK_01392	1.28e-69	-	-	-	M	-	-	-	domain protein
HCBKGIIK_01393	4.96e-64	-	-	-	-	-	-	-	-
HCBKGIIK_01394	8.72e-235	ampC	-	-	V	-	-	-	Beta-lactamase
HCBKGIIK_01395	1.96e-292	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HCBKGIIK_01396	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HCBKGIIK_01397	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HCBKGIIK_01398	3.26e-296	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HCBKGIIK_01400	2.82e-172	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HCBKGIIK_01401	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HCBKGIIK_01402	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HCBKGIIK_01403	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCBKGIIK_01404	9.58e-211	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCBKGIIK_01405	1.09e-250	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCBKGIIK_01406	1.01e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCBKGIIK_01407	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCBKGIIK_01408	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCBKGIIK_01409	1.65e-246	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HCBKGIIK_01410	5.74e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HCBKGIIK_01411	1.39e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HCBKGIIK_01412	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HCBKGIIK_01413	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBKGIIK_01414	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCBKGIIK_01415	3.96e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBKGIIK_01416	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCBKGIIK_01417	7.51e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCBKGIIK_01418	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCBKGIIK_01419	7.36e-89	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HCBKGIIK_01420	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HCBKGIIK_01421	4.97e-307	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCBKGIIK_01422	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HCBKGIIK_01423	4.61e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HCBKGIIK_01424	9.49e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HCBKGIIK_01425	8.55e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HCBKGIIK_01426	7.38e-274	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HCBKGIIK_01427	1.23e-15	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCBKGIIK_01428	1.53e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HCBKGIIK_01429	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCBKGIIK_01430	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HCBKGIIK_01431	2.32e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HCBKGIIK_01432	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HCBKGIIK_01433	3.47e-123	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HCBKGIIK_01434	2.95e-201	yvgN	-	-	S	-	-	-	Aldo keto reductase
HCBKGIIK_01435	2.52e-263	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HCBKGIIK_01436	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HCBKGIIK_01437	5.13e-61	-	-	-	-	-	-	-	-
HCBKGIIK_01438	1.27e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HCBKGIIK_01439	8.27e-111	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HCBKGIIK_01440	1.36e-96	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HCBKGIIK_01441	8.05e-178	-	-	-	S	-	-	-	Membrane
HCBKGIIK_01442	9.4e-178	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HCBKGIIK_01443	2.68e-36	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCBKGIIK_01444	6.46e-250	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCBKGIIK_01445	6.17e-38	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCBKGIIK_01446	2.04e-39	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HCBKGIIK_01447	2.82e-216	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HCBKGIIK_01448	3.35e-59	-	-	-	S	-	-	-	Pfam:DUF59
HCBKGIIK_01449	4.48e-90	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HCBKGIIK_01450	2.02e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HCBKGIIK_01451	1.61e-48	-	-	-	-	-	-	-	-
HCBKGIIK_01452	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01453	2.37e-152	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01454	7.46e-222	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HCBKGIIK_01455	1.46e-110	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HCBKGIIK_01456	7.01e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HCBKGIIK_01457	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HCBKGIIK_01458	2.94e-72	-	-	-	-	-	-	-	-
HCBKGIIK_01459	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCBKGIIK_01461	3.95e-07	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HCBKGIIK_01462	2.76e-256	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HCBKGIIK_01463	9.51e-127	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HCBKGIIK_01464	6.46e-73	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HCBKGIIK_01465	5.69e-314	-	-	-	E	ko:K03294	-	ko00000	amino acid
HCBKGIIK_01466	1.1e-152	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCBKGIIK_01468	1.02e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HCBKGIIK_01469	3.33e-39	-	-	-	S	-	-	-	Cytochrome B5
HCBKGIIK_01470	4.97e-97	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HCBKGIIK_01471	1.11e-156	-	-	-	GM	-	-	-	NmrA-like family
HCBKGIIK_01472	1.07e-66	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCBKGIIK_01473	6.45e-138	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HCBKGIIK_01474	1.78e-106	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCBKGIIK_01475	6.84e-293	-	-	-	-	-	-	-	-
HCBKGIIK_01476	2.65e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HCBKGIIK_01477	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HCBKGIIK_01478	8.37e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HCBKGIIK_01479	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HCBKGIIK_01480	1.08e-62	ywnA	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_01481	5.03e-34	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HCBKGIIK_01482	2.03e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HCBKGIIK_01483	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HCBKGIIK_01484	9.8e-156	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HCBKGIIK_01485	1.18e-245	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HCBKGIIK_01486	4.06e-108	-	-	-	-	-	-	-	-
HCBKGIIK_01487	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HCBKGIIK_01488	3.98e-176	-	-	-	T	-	-	-	EAL domain
HCBKGIIK_01489	4.69e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HCBKGIIK_01490	3.65e-78	-	-	-	-	-	-	-	-
HCBKGIIK_01491	9.48e-128	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HCBKGIIK_01492	6.67e-204	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HCBKGIIK_01493	4.06e-188	-	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_01494	5.69e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HCBKGIIK_01495	5.88e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HCBKGIIK_01496	1.67e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HCBKGIIK_01497	4.61e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HCBKGIIK_01498	4.88e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HCBKGIIK_01499	2.44e-114	-	-	-	S	-	-	-	Alpha beta hydrolase
HCBKGIIK_01500	3.49e-16	-	-	-	S	-	-	-	Alpha beta hydrolase
HCBKGIIK_01501	3.1e-170	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HCBKGIIK_01502	3.38e-110	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HCBKGIIK_01503	1.64e-203	lysR	-	-	K	-	-	-	Transcriptional regulator
HCBKGIIK_01504	5.96e-32	-	-	-	-	-	-	-	-
HCBKGIIK_01505	5.39e-111	-	-	-	C	-	-	-	Flavodoxin
HCBKGIIK_01506	3.91e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HCBKGIIK_01507	4.31e-233	-	-	-	C	-	-	-	nadph quinone reductase
HCBKGIIK_01508	3.32e-72	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HCBKGIIK_01509	4.64e-143	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HCBKGIIK_01510	6.46e-288	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HCBKGIIK_01511	1.41e-117	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HCBKGIIK_01512	5.45e-282	-	-	-	T	-	-	-	GHKL domain
HCBKGIIK_01513	3.12e-151	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HCBKGIIK_01514	1.18e-201	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HCBKGIIK_01515	8.27e-110	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_01516	1.11e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HCBKGIIK_01517	6.95e-59	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HCBKGIIK_01518	7.44e-51	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCBKGIIK_01519	3.99e-143	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCBKGIIK_01520	4.89e-165	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HCBKGIIK_01521	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCBKGIIK_01522	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HCBKGIIK_01523	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HCBKGIIK_01524	4.16e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HCBKGIIK_01525	6.54e-28	yagE	-	-	E	-	-	-	amino acid
HCBKGIIK_01526	2.33e-224	yagE	-	-	E	-	-	-	amino acid
HCBKGIIK_01527	2.14e-148	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HCBKGIIK_01528	2.16e-121	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HCBKGIIK_01529	1.69e-44	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HCBKGIIK_01530	6.89e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HCBKGIIK_01531	5.46e-233	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HCBKGIIK_01532	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HCBKGIIK_01533	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCBKGIIK_01535	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCBKGIIK_01536	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCBKGIIK_01537	7.32e-105	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HCBKGIIK_01538	0.0	-	-	-	E	-	-	-	amino acid
HCBKGIIK_01539	0.0	ydaO	-	-	E	-	-	-	amino acid
HCBKGIIK_01540	1.53e-52	-	-	-	-	-	-	-	-
HCBKGIIK_01542	3.98e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
HCBKGIIK_01543	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HCBKGIIK_01544	6.03e-183	-	-	-	L	-	-	-	PFAM transposase IS116 IS110 IS902
HCBKGIIK_01545	1.61e-291	-	-	-	P	-	-	-	Chloride transporter, ClC family
HCBKGIIK_01546	2.6e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCBKGIIK_01547	4.77e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HCBKGIIK_01548	1.26e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCBKGIIK_01549	3.26e-89	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HCBKGIIK_01550	9.54e-78	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HCBKGIIK_01551	2.6e-135	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_01553	6.7e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCBKGIIK_01554	9.19e-226	-	-	-	-	-	-	-	-
HCBKGIIK_01555	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCBKGIIK_01556	1.66e-309	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HCBKGIIK_01557	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HCBKGIIK_01558	2.37e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCBKGIIK_01559	4.6e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HCBKGIIK_01560	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCBKGIIK_01561	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBKGIIK_01562	1.98e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBKGIIK_01563	4.5e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBKGIIK_01564	5.23e-170	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HCBKGIIK_01565	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCBKGIIK_01566	5.01e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCBKGIIK_01567	4.26e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCBKGIIK_01568	1e-126	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCBKGIIK_01569	3.61e-219	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HCBKGIIK_01570	5.38e-234	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HCBKGIIK_01571	9.67e-31	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HCBKGIIK_01572	2.11e-24	mocA	-	-	S	-	-	-	Oxidoreductase
HCBKGIIK_01573	1.23e-163	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HCBKGIIK_01574	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HCBKGIIK_01575	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HCBKGIIK_01576	3.86e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
HCBKGIIK_01577	8.13e-292	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HCBKGIIK_01578	1.85e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HCBKGIIK_01579	7.47e-148	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HCBKGIIK_01580	1.51e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCBKGIIK_01581	3.95e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCBKGIIK_01582	7.94e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCBKGIIK_01583	2.13e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCBKGIIK_01584	2.57e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HCBKGIIK_01585	1.29e-25	-	-	-	K	-	-	-	LysR substrate binding domain
HCBKGIIK_01586	1.92e-90	-	-	-	K	-	-	-	LysR substrate binding domain
HCBKGIIK_01587	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HCBKGIIK_01588	9.75e-186	-	-	-	E	-	-	-	AzlC protein
HCBKGIIK_01589	9.17e-265	hpk31	-	-	T	-	-	-	Histidine kinase
HCBKGIIK_01590	9.76e-161	vanR	-	-	K	-	-	-	response regulator
HCBKGIIK_01591	8.49e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCBKGIIK_01592	6.79e-218	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HCBKGIIK_01593	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HCBKGIIK_01594	6.43e-300	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HCBKGIIK_01595	4.64e-298	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HCBKGIIK_01596	9.74e-154	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCBKGIIK_01597	4.25e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HCBKGIIK_01598	1.75e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCBKGIIK_01599	2.37e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HCBKGIIK_01600	1.38e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCBKGIIK_01601	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HCBKGIIK_01602	3.79e-193	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HCBKGIIK_01603	1.36e-157	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HCBKGIIK_01604	1.47e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HCBKGIIK_01605	8.26e-219	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HCBKGIIK_01606	2.4e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HCBKGIIK_01607	2.51e-285	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HCBKGIIK_01608	3.28e-177	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01609	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCBKGIIK_01610	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCBKGIIK_01611	1.67e-45	-	-	-	L	-	-	-	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HCBKGIIK_01612	1.28e-35	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HCBKGIIK_01613	1.39e-225	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCBKGIIK_01614	1.27e-259	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HCBKGIIK_01615	2.01e-130	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HCBKGIIK_01616	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBKGIIK_01617	3.83e-22	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCBKGIIK_01618	2.76e-183	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCBKGIIK_01619	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HCBKGIIK_01620	9.89e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HCBKGIIK_01621	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HCBKGIIK_01622	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01624	4e-89	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_01625	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HCBKGIIK_01626	2.87e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCBKGIIK_01627	2.13e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCBKGIIK_01628	3.96e-254	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HCBKGIIK_01629	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCBKGIIK_01630	8.08e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
HCBKGIIK_01631	5.87e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HCBKGIIK_01632	1.46e-196	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCBKGIIK_01633	9.29e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HCBKGIIK_01634	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HCBKGIIK_01635	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HCBKGIIK_01636	2.67e-170	-	-	-	D	-	-	-	transport
HCBKGIIK_01637	3.13e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HCBKGIIK_01638	4.67e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HCBKGIIK_01639	3.86e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
HCBKGIIK_01640	3.58e-106	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HCBKGIIK_01641	1.76e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCBKGIIK_01642	4.44e-292	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HCBKGIIK_01643	1.73e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HCBKGIIK_01644	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBKGIIK_01645	1.95e-68	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HCBKGIIK_01646	2.32e-232	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HCBKGIIK_01649	3.55e-154	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HCBKGIIK_01650	3.37e-193	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCBKGIIK_01651	3.25e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HCBKGIIK_01652	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HCBKGIIK_01653	4.6e-173	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_01654	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCBKGIIK_01655	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HCBKGIIK_01656	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HCBKGIIK_01657	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCBKGIIK_01658	3.9e-116	-	-	-	-	-	-	-	-
HCBKGIIK_01659	8e-49	-	-	-	-	-	-	-	-
HCBKGIIK_01660	1.64e-13	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HCBKGIIK_01661	1.24e-217	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HCBKGIIK_01662	3.76e-175	epsB	-	-	M	-	-	-	biosynthesis protein
HCBKGIIK_01663	4.11e-152	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HCBKGIIK_01664	4.08e-138	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HCBKGIIK_01665	2.76e-164	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HCBKGIIK_01666	2.44e-56	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HCBKGIIK_01667	1.16e-103	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HCBKGIIK_01668	3.3e-197	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HCBKGIIK_01669	7.58e-189	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HCBKGIIK_01670	8.88e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCBKGIIK_01671	2.04e-72	-	-	-	-	-	-	-	-
HCBKGIIK_01672	1.21e-266	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HCBKGIIK_01673	6.62e-233	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HCBKGIIK_01674	6.09e-174	-	-	-	-	-	-	-	-
HCBKGIIK_01675	7.07e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HCBKGIIK_01676	5.68e-233	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HCBKGIIK_01677	2.04e-231	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HCBKGIIK_01678	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HCBKGIIK_01679	1.18e-99	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HCBKGIIK_01680	1.88e-53	-	-	-	-	-	-	-	-
HCBKGIIK_01681	6.3e-90	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HCBKGIIK_01683	4.01e-183	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HCBKGIIK_01684	4.36e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBKGIIK_01685	1.71e-143	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HCBKGIIK_01686	2.66e-120	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HCBKGIIK_01687	6.76e-170	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCBKGIIK_01688	6.92e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HCBKGIIK_01689	1.06e-148	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HCBKGIIK_01690	1.25e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCBKGIIK_01691	1.01e-186	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCBKGIIK_01692	4.43e-183	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HCBKGIIK_01693	4.03e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCBKGIIK_01694	3.93e-45	-	-	-	-	-	-	-	-
HCBKGIIK_01695	6.69e-77	-	-	-	-	-	-	-	-
HCBKGIIK_01696	1.51e-51	-	-	-	-	-	-	-	-
HCBKGIIK_01697	3.54e-179	-	-	-	L	-	-	-	Bacterial dnaA protein
HCBKGIIK_01698	3.38e-294	-	-	-	L	-	-	-	Integrase core domain
HCBKGIIK_01699	3.2e-76	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HCBKGIIK_01700	6.07e-315	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCBKGIIK_01701	6.54e-222	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCBKGIIK_01702	2.6e-33	-	-	-	-	-	-	-	-
HCBKGIIK_01703	8.12e-144	-	-	-	-	-	-	-	-
HCBKGIIK_01704	2.76e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
HCBKGIIK_01705	3.24e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HCBKGIIK_01706	1.42e-112	-	-	-	-	-	-	-	-
HCBKGIIK_01707	2.49e-141	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HCBKGIIK_01708	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HCBKGIIK_01709	4.02e-159	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HCBKGIIK_01711	1.46e-126	-	-	-	-	-	-	-	-
HCBKGIIK_01712	1.89e-275	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HCBKGIIK_01713	4.79e-87	-	-	-	S	-	-	-	Alpha beta hydrolase
HCBKGIIK_01714	6.21e-82	-	-	-	S	-	-	-	Alpha beta hydrolase
HCBKGIIK_01715	8.15e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HCBKGIIK_01716	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCBKGIIK_01717	1.7e-54	-	-	-	-	-	-	-	-
HCBKGIIK_01718	9.5e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HCBKGIIK_01719	5.37e-45	-	-	-	K	-	-	-	Bacterial transcriptional regulator
HCBKGIIK_01720	7.63e-90	-	1.1.1.100, 1.1.1.304, 1.1.1.76	-	IQ	ko:K00059,ko:K18009	ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HCBKGIIK_01721	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HCBKGIIK_01722	2.22e-312	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HCBKGIIK_01723	4.79e-307	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HCBKGIIK_01724	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCBKGIIK_01725	3.34e-215	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HCBKGIIK_01726	2.09e-214	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HCBKGIIK_01727	1.08e-168	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HCBKGIIK_01728	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HCBKGIIK_01729	1.15e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HCBKGIIK_01730	1.33e-73	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HCBKGIIK_01731	6.27e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
HCBKGIIK_01732	4.63e-176	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01733	3.37e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HCBKGIIK_01734	7.44e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HCBKGIIK_01735	4.41e-158	-	-	-	M	-	-	-	PFAM NLP P60 protein
HCBKGIIK_01736	5.85e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HCBKGIIK_01737	5.78e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HCBKGIIK_01757	3.87e-100	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01758	1.68e-187	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01760	3.12e-250	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HCBKGIIK_01761	8.76e-201	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HCBKGIIK_01762	3.75e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCBKGIIK_01763	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HCBKGIIK_01764	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HCBKGIIK_01765	6.9e-77	-	-	-	-	-	-	-	-
HCBKGIIK_01766	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HCBKGIIK_01767	2.1e-220	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCBKGIIK_01768	9.94e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HCBKGIIK_01769	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HCBKGIIK_01770	7.73e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCBKGIIK_01771	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCBKGIIK_01772	1.98e-258	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCBKGIIK_01773	2.35e-183	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCBKGIIK_01774	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCBKGIIK_01775	8.44e-284	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCBKGIIK_01776	1.11e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCBKGIIK_01777	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HCBKGIIK_01778	2.5e-188	ylmH	-	-	S	-	-	-	S4 domain protein
HCBKGIIK_01779	8.87e-101	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HCBKGIIK_01789	8.19e-202	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HCBKGIIK_01790	2.99e-66	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HCBKGIIK_01791	1.21e-53	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HCBKGIIK_01792	1.86e-32	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HCBKGIIK_01793	4.2e-163	-	-	-	F	-	-	-	helicase superfamily c-terminal domain
HCBKGIIK_01795	1.63e-94	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HCBKGIIK_01796	4.37e-39	-	-	-	-	-	-	-	-
HCBKGIIK_01797	1.69e-55	-	-	-	-	-	-	-	-
HCBKGIIK_01798	2.98e-269	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HCBKGIIK_01799	1.06e-125	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HCBKGIIK_01800	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HCBKGIIK_01801	1.06e-92	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCBKGIIK_01802	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HCBKGIIK_01803	7.47e-63	-	-	-	S	-	-	-	VRR_NUC
HCBKGIIK_01804	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HCBKGIIK_01805	1.76e-113	-	-	-	-	-	-	-	-
HCBKGIIK_01806	2.4e-130	-	-	-	-	-	-	-	-
HCBKGIIK_01807	9.68e-292	-	-	-	KL	-	-	-	DNA methylase
HCBKGIIK_01808	3.45e-145	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HCBKGIIK_01809	8.38e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
HCBKGIIK_01810	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HCBKGIIK_01811	2.37e-310	-	-	-	S	-	-	-	Phage portal protein
HCBKGIIK_01812	9.4e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HCBKGIIK_01813	1.29e-281	-	-	-	S	-	-	-	Phage capsid family
HCBKGIIK_01814	6.21e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HCBKGIIK_01815	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
HCBKGIIK_01816	5.95e-92	-	-	-	S	-	-	-	Bacteriophage holin family
HCBKGIIK_01817	8.75e-184	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HCBKGIIK_01818	1.03e-37	-	-	-	-	-	-	-	-
HCBKGIIK_01819	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HCBKGIIK_01820	0.0	-	-	-	L	-	-	-	Recombinase
HCBKGIIK_01821	9.37e-163	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HCBKGIIK_01822	2.68e-162	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HCBKGIIK_01823	8.37e-87	-	-	-	K	-	-	-	LytTr DNA-binding domain
HCBKGIIK_01824	1.87e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HCBKGIIK_01825	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBKGIIK_01826	4.7e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HCBKGIIK_01827	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBKGIIK_01828	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCBKGIIK_01829	9.59e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBKGIIK_01830	4.51e-260	camS	-	-	S	-	-	-	sex pheromone
HCBKGIIK_01831	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCBKGIIK_01832	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HCBKGIIK_01833	4.55e-267	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCBKGIIK_01834	2.75e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCBKGIIK_01835	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HCBKGIIK_01836	2.58e-179	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HCBKGIIK_01837	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HCBKGIIK_01838	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCBKGIIK_01839	3.54e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCBKGIIK_01840	2.89e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBKGIIK_01841	3.8e-194	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBKGIIK_01842	2.96e-178	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBKGIIK_01843	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HCBKGIIK_01844	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBKGIIK_01845	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCBKGIIK_01846	2.19e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCBKGIIK_01847	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HCBKGIIK_01848	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCBKGIIK_01849	6.16e-159	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCBKGIIK_01850	9.61e-305	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCBKGIIK_01851	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HCBKGIIK_01852	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HCBKGIIK_01853	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCBKGIIK_01854	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCBKGIIK_01855	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCBKGIIK_01856	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCBKGIIK_01857	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBKGIIK_01858	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCBKGIIK_01859	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCBKGIIK_01860	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCBKGIIK_01861	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCBKGIIK_01862	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HCBKGIIK_01863	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCBKGIIK_01864	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCBKGIIK_01865	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCBKGIIK_01866	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCBKGIIK_01867	1.16e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCBKGIIK_01868	4.22e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCBKGIIK_01869	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HCBKGIIK_01870	7.75e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCBKGIIK_01871	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HCBKGIIK_01872	1.92e-299	isp	-	-	L	-	-	-	Transposase
HCBKGIIK_01873	9.65e-175	-	-	-	L	ko:K07487	-	ko00000	Transposase
HCBKGIIK_01874	7.44e-82	-	-	-	L	ko:K07487	-	ko00000	Transposase
HCBKGIIK_01875	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCBKGIIK_01876	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCBKGIIK_01877	3.56e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCBKGIIK_01878	1.86e-142	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HCBKGIIK_01879	1.06e-259	-	-	-	-	-	-	-	-
HCBKGIIK_01880	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBKGIIK_01881	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBKGIIK_01882	8.51e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HCBKGIIK_01883	2.19e-306	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCBKGIIK_01884	5.61e-292	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCBKGIIK_01885	2.7e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HCBKGIIK_01886	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
HCBKGIIK_01887	2.65e-56	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HCBKGIIK_01888	1.62e-81	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HCBKGIIK_01890	1.2e-162	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBKGIIK_01891	1.94e-268	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HCBKGIIK_01892	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCBKGIIK_01893	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HCBKGIIK_01894	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HCBKGIIK_01895	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HCBKGIIK_01896	5.67e-180	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HCBKGIIK_01897	9.65e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HCBKGIIK_01898	4.65e-230	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBKGIIK_01899	2.91e-183	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HCBKGIIK_01900	1.82e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCBKGIIK_01901	1.72e-166	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HCBKGIIK_01902	3.48e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCBKGIIK_01903	1.29e-182	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCBKGIIK_01904	5.83e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HCBKGIIK_01905	8.1e-299	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HCBKGIIK_01906	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCBKGIIK_01907	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBKGIIK_01908	6.36e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HCBKGIIK_01909	1.18e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HCBKGIIK_01910	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HCBKGIIK_01911	7.97e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HCBKGIIK_01912	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCBKGIIK_01913	2.79e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCBKGIIK_01914	1.85e-210	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCBKGIIK_01915	3.13e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HCBKGIIK_01916	1.04e-83	-	-	-	-	-	-	-	-
HCBKGIIK_01917	7.6e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCBKGIIK_01918	3.69e-114	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCBKGIIK_01919	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HCBKGIIK_01920	1.81e-272	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCBKGIIK_01921	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCBKGIIK_01922	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HCBKGIIK_01923	2.49e-255	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HCBKGIIK_01925	1.31e-219	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HCBKGIIK_01926	3.36e-77	-	-	-	-	-	-	-	-
HCBKGIIK_01927	1.89e-228	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HCBKGIIK_01928	1.08e-161	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCBKGIIK_01929	1.94e-68	-	-	-	-	-	-	-	-
HCBKGIIK_01930	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCBKGIIK_01931	7.65e-101	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCBKGIIK_01932	3.62e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HCBKGIIK_01933	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCBKGIIK_01934	1.05e-168	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01935	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HCBKGIIK_01936	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HCBKGIIK_01937	1.35e-91	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HCBKGIIK_01938	5.92e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCBKGIIK_01939	2.07e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCBKGIIK_01940	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HCBKGIIK_01941	3.65e-111	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HCBKGIIK_01942	2.54e-219	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCBKGIIK_01943	2.22e-231	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HCBKGIIK_01944	2.21e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCBKGIIK_01945	1.66e-77	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HCBKGIIK_01946	1.08e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCBKGIIK_01947	1.02e-187	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HCBKGIIK_01948	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HCBKGIIK_01949	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HCBKGIIK_01950	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCBKGIIK_01951	1.03e-265	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCBKGIIK_01952	7.19e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HCBKGIIK_01953	1.27e-159	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HCBKGIIK_01954	1.1e-193	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCBKGIIK_01955	2.61e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HCBKGIIK_01956	3.79e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HCBKGIIK_01957	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HCBKGIIK_01958	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HCBKGIIK_01959	1.47e-212	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HCBKGIIK_01960	5.3e-208	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HCBKGIIK_01961	1.01e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBKGIIK_01962	9.25e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCBKGIIK_01963	5.49e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCBKGIIK_01964	3.01e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HCBKGIIK_01965	8.52e-130	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCBKGIIK_01966	1.43e-250	-	-	-	S	-	-	-	Helix-turn-helix domain
HCBKGIIK_01967	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HCBKGIIK_01968	1.04e-69	-	-	-	M	-	-	-	Lysin motif
HCBKGIIK_01969	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HCBKGIIK_01970	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HCBKGIIK_01971	9.51e-317	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HCBKGIIK_01972	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCBKGIIK_01973	7.47e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HCBKGIIK_01974	5.76e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCBKGIIK_01975	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HCBKGIIK_01976	1.41e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCBKGIIK_01977	1.95e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCBKGIIK_01978	5.85e-141	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HCBKGIIK_01979	1.83e-195	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HCBKGIIK_01980	7.3e-216	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HCBKGIIK_01981	4.73e-140	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HCBKGIIK_01982	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HCBKGIIK_01983	2.08e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCBKGIIK_01984	5.03e-181	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBKGIIK_01985	1.07e-204	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HCBKGIIK_01986	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCBKGIIK_01987	5.11e-208	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HCBKGIIK_01988	1.23e-135	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCBKGIIK_01989	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBKGIIK_01990	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBKGIIK_01991	1.02e-103	-	-	-	F	-	-	-	NUDIX domain
HCBKGIIK_01992	7.36e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HCBKGIIK_01993	2.49e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HCBKGIIK_01994	1.96e-35	-	-	-	-	-	-	-	-
HCBKGIIK_01996	8.23e-112	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HCBKGIIK_01997	1.57e-80	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HCBKGIIK_01998	6.23e-35	-	-	-	-	-	-	-	-
HCBKGIIK_01999	1.09e-122	-	-	-	-	-	-	-	-
HCBKGIIK_02000	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HCBKGIIK_02001	3.28e-232	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HCBKGIIK_02002	1.89e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HCBKGIIK_02003	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HCBKGIIK_02004	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HCBKGIIK_02005	2.2e-62	-	-	-	-	-	-	-	-
HCBKGIIK_02006	1.81e-41	-	-	-	-	-	-	-	-
HCBKGIIK_02007	7.29e-60	-	-	-	-	-	-	-	-
HCBKGIIK_02008	5.53e-127	-	-	-	L	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HCBKGIIK_02009	0.0	-	-	-	L	-	-	-	PLD-like domain
HCBKGIIK_02013	5.6e-46	-	-	-	S	-	-	-	Acyltransferase family
HCBKGIIK_02014	7.55e-120	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HCBKGIIK_02015	4.17e-53	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HCBKGIIK_02016	5.27e-38	-	2.3.1.79	-	M	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
HCBKGIIK_02017	1.61e-40	-	-	-	-	-	-	-	-