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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
GHALPPDB_00001	1.95e-07	-	-	-	E	-	-	-	Preprotein translocase subunit SecB
GHALPPDB_00004	1.7e-82	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
GHALPPDB_00021	1.13e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GHALPPDB_00022	2.87e-141	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
GHALPPDB_00023	2.23e-150	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
GHALPPDB_00024	4.67e-163	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
GHALPPDB_00025	1.33e-40	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_00026	9.53e-23	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
GHALPPDB_00027	3.95e-41	-	-	-	S	-	-	-	HicB family
GHALPPDB_00028	1.61e-36	-	-	-	-	-	-	-	-
GHALPPDB_00029	1.76e-102	-	-	-	-	-	-	-	-
GHALPPDB_00030	3.27e-69	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
GHALPPDB_00031	4.63e-184	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
GHALPPDB_00032	1.6e-287	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GHALPPDB_00033	3.15e-99	-	-	-	-	-	-	-	-
GHALPPDB_00034	4.26e-128	-	-	-	-	-	-	-	-
GHALPPDB_00035	7.6e-139	-	-	-	L	-	-	-	Integrase
GHALPPDB_00037	8.48e-24	repA	-	-	S	-	-	-	Replication initiator protein A
GHALPPDB_00038	1.36e-267	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
GHALPPDB_00039	1.2e-87	-	-	-	S	-	-	-	GtrA-like protein
GHALPPDB_00040	1.47e-215	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
GHALPPDB_00041	4.99e-71	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GHALPPDB_00042	1.21e-106	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GHALPPDB_00043	1.92e-114	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
GHALPPDB_00044	1.19e-130	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
GHALPPDB_00045	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GHALPPDB_00046	1.25e-302	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
GHALPPDB_00047	4.33e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GHALPPDB_00048	3.32e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
GHALPPDB_00049	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
GHALPPDB_00050	3.36e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
GHALPPDB_00051	1.97e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
GHALPPDB_00052	1.09e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
GHALPPDB_00053	8.66e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
GHALPPDB_00054	8.25e-79	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
GHALPPDB_00055	6.2e-53	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
GHALPPDB_00056	4.52e-62	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
GHALPPDB_00057	8.99e-99	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
GHALPPDB_00058	3.29e-232	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GHALPPDB_00059	2.2e-70	ftsL	-	-	D	-	-	-	Cell division protein FtsL
GHALPPDB_00060	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GHALPPDB_00061	5.4e-225	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GHALPPDB_00062	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GHALPPDB_00063	9.95e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GHALPPDB_00064	2.83e-181	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GHALPPDB_00065	4.95e-305	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GHALPPDB_00066	5.53e-262	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GHALPPDB_00067	1.04e-94	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GHALPPDB_00068	5.07e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
GHALPPDB_00069	1.1e-189	ylmH	-	-	S	-	-	-	S4 domain protein
GHALPPDB_00070	4.81e-163	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
GHALPPDB_00071	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GHALPPDB_00072	1.15e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
GHALPPDB_00073	3.64e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
GHALPPDB_00074	2.13e-55	-	-	-	-	-	-	-	-
GHALPPDB_00075	1.69e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GHALPPDB_00076	1.28e-273	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GHALPPDB_00077	2.01e-74	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
GHALPPDB_00078	3.28e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GHALPPDB_00079	7.2e-158	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
GHALPPDB_00080	1.82e-144	-	-	-	S	-	-	-	repeat protein
GHALPPDB_00081	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GHALPPDB_00082	8.04e-228	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
GHALPPDB_00083	1.47e-206	-	-	-	L	-	-	-	Transposase
GHALPPDB_00084	2.7e-278	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
GHALPPDB_00086	1.55e-123	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
GHALPPDB_00087	3.84e-70	-	-	-	-	-	-	-	-
GHALPPDB_00088	1.78e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GHALPPDB_00089	1.62e-261	-	-	-	L	-	-	-	Probable transposase
GHALPPDB_00090	1.51e-57	-	-	-	-	-	-	-	-
GHALPPDB_00091	4.71e-32	-	-	-	-	-	-	-	-
GHALPPDB_00092	1e-106	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
GHALPPDB_00093	6.31e-29	-	-	-	-	-	-	-	-
GHALPPDB_00094	3.3e-171	-	-	-	S	-	-	-	Peptidase_C39 like family
GHALPPDB_00095	6.17e-95	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GHALPPDB_00096	8.03e-41	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GHALPPDB_00097	2.99e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
GHALPPDB_00098	1.61e-224	degV1	-	-	S	-	-	-	DegV family
GHALPPDB_00099	8.1e-209	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
GHALPPDB_00100	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
GHALPPDB_00101	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GHALPPDB_00102	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
GHALPPDB_00103	3.08e-41	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_00104	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GHALPPDB_00105	4.15e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GHALPPDB_00106	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
GHALPPDB_00107	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHALPPDB_00108	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GHALPPDB_00109	2.09e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GHALPPDB_00110	4.08e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
GHALPPDB_00111	5.01e-255	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GHALPPDB_00112	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GHALPPDB_00113	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
GHALPPDB_00114	1.31e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GHALPPDB_00115	4.38e-188	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHALPPDB_00116	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GHALPPDB_00117	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GHALPPDB_00118	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
GHALPPDB_00119	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GHALPPDB_00120	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GHALPPDB_00121	1.25e-264	-	-	-	-	-	-	-	-
GHALPPDB_00122	6.46e-27	-	-	-	-	-	-	-	-
GHALPPDB_00123	1.14e-90	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
GHALPPDB_00124	7.33e-151	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
GHALPPDB_00125	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
GHALPPDB_00126	2.57e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
GHALPPDB_00127	4.19e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
GHALPPDB_00128	8.25e-101	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
GHALPPDB_00129	4.82e-46	-	-	-	-	-	-	-	-
GHALPPDB_00130	2.46e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GHALPPDB_00131	4.48e-60	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_00132	3e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
GHALPPDB_00133	4.48e-60	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_00134	1.37e-239	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
GHALPPDB_00135	8.38e-109	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GHALPPDB_00136	1.65e-205	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00137	6.04e-189	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
GHALPPDB_00138	5.41e-143	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
GHALPPDB_00141	5.2e-188	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GHALPPDB_00142	2.02e-117	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
GHALPPDB_00143	3.83e-227	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
GHALPPDB_00144	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
GHALPPDB_00145	1.34e-233	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHALPPDB_00146	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GHALPPDB_00147	2.03e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
GHALPPDB_00148	3.86e-73	steT	-	-	E	ko:K03294	-	ko00000	amino acid
GHALPPDB_00149	5.25e-39	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
GHALPPDB_00150	3.9e-306	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
GHALPPDB_00151	6.01e-265	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
GHALPPDB_00152	4.77e-258	-	-	-	-	-	-	-	-
GHALPPDB_00153	1.29e-123	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GHALPPDB_00154	1.74e-36	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GHALPPDB_00155	2.85e-58	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
GHALPPDB_00156	5.45e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GHALPPDB_00157	4.99e-10	-	-	-	-	-	-	-	-
GHALPPDB_00158	5.43e-133	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
GHALPPDB_00159	8.9e-51	-	-	-	-	-	-	-	-
GHALPPDB_00160	2.18e-236	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
GHALPPDB_00161	8.26e-82	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_00162	3.23e-45	-	-	-	-	-	-	-	-
GHALPPDB_00163	7.5e-308	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
GHALPPDB_00164	3.88e-91	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
GHALPPDB_00165	3.52e-16	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
GHALPPDB_00166	7.23e-22	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GHALPPDB_00167	7.31e-75	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
GHALPPDB_00168	1.31e-78	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GHALPPDB_00170	1.89e-91	-	-	-	GK	-	-	-	ROK family
GHALPPDB_00171	7.47e-82	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
GHALPPDB_00172	2.17e-138	-	-	-	C	-	-	-	nitroreductase
GHALPPDB_00173	1.53e-162	-	-	-	S	-	-	-	KR domain
GHALPPDB_00174	3.75e-122	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
GHALPPDB_00175	2.75e-09	-	-	-	-	-	-	-	-
GHALPPDB_00176	6.8e-130	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
GHALPPDB_00177	1.59e-74	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
GHALPPDB_00178	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
GHALPPDB_00179	6.09e-240	flp	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_00180	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GHALPPDB_00181	1.75e-123	-	-	-	-	-	-	-	-
GHALPPDB_00182	4.54e-59	-	-	-	-	-	-	-	-
GHALPPDB_00183	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
GHALPPDB_00184	4.84e-11	-	-	-	-	-	-	-	-
GHALPPDB_00185	2.66e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
GHALPPDB_00186	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHALPPDB_00187	2.37e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
GHALPPDB_00188	1.05e-112	-	-	-	-	-	-	-	-
GHALPPDB_00189	2.6e-96	-	-	-	-	-	-	-	-
GHALPPDB_00190	4.02e-204	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
GHALPPDB_00191	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GHALPPDB_00192	8.18e-304	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_00193	3.43e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
GHALPPDB_00194	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
GHALPPDB_00195	3.55e-39	-	-	-	-	-	-	-	-
GHALPPDB_00196	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
GHALPPDB_00197	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GHALPPDB_00198	4.42e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GHALPPDB_00199	2.5e-176	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GHALPPDB_00200	1.08e-203	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
GHALPPDB_00201	5.3e-144	yjbH	-	-	Q	-	-	-	Thioredoxin
GHALPPDB_00202	6.91e-139	-	-	-	S	-	-	-	CYTH
GHALPPDB_00203	1.63e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
GHALPPDB_00204	2.52e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GHALPPDB_00205	6.77e-216	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GHALPPDB_00206	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GHALPPDB_00207	2.05e-88	-	-	-	S	-	-	-	SNARE associated Golgi protein
GHALPPDB_00208	4.12e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
GHALPPDB_00209	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
GHALPPDB_00210	2.72e-85	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
GHALPPDB_00211	1.16e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
GHALPPDB_00212	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GHALPPDB_00213	4.46e-90	WQ51_03320	-	-	S	-	-	-	Protein of unknown function (DUF1149)
GHALPPDB_00214	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
GHALPPDB_00215	4.05e-289	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
GHALPPDB_00216	1.85e-301	ymfH	-	-	S	-	-	-	Peptidase M16
GHALPPDB_00217	1.89e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
GHALPPDB_00218	1.33e-186	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
GHALPPDB_00219	3e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GHALPPDB_00220	8.51e-246	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GHALPPDB_00221	5.81e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
GHALPPDB_00223	5.01e-41	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
GHALPPDB_00224	7.94e-132	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00228	3.86e-27	-	-	-	K	-	-	-	DNA-binding transcription factor activity
GHALPPDB_00229	4.46e-60	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00230	1.77e-61	-	-	-	-	-	-	-	-
GHALPPDB_00231	7.2e-197	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
GHALPPDB_00232	7e-103	-	-	-	S	-	-	-	Putative adhesin
GHALPPDB_00233	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
GHALPPDB_00234	1.37e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
GHALPPDB_00235	9e-66	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
GHALPPDB_00236	1.06e-258	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
GHALPPDB_00237	0.0	cadA	-	-	P	-	-	-	P-type ATPase
GHALPPDB_00238	1.69e-107	ykuL	-	-	S	-	-	-	(CBS) domain
GHALPPDB_00239	3.66e-274	-	-	-	S	-	-	-	Membrane
GHALPPDB_00240	2.34e-66	-	-	-	-	-	-	-	-
GHALPPDB_00241	3.2e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
GHALPPDB_00242	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHALPPDB_00243	2.08e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
GHALPPDB_00244	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GHALPPDB_00245	1.05e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GHALPPDB_00246	2.66e-221	pbpX2	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_00248	1.87e-11	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GHALPPDB_00249	1.37e-56	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GHALPPDB_00250	7.99e-37	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GHALPPDB_00251	8.02e-38	-	-	-	-	-	-	-	-
GHALPPDB_00252	2.66e-64	-	-	-	-	-	-	-	-
GHALPPDB_00253	1.75e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
GHALPPDB_00254	6.7e-200	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GHALPPDB_00255	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GHALPPDB_00256	3.96e-49	-	-	-	-	-	-	-	-
GHALPPDB_00257	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GHALPPDB_00258	1.38e-73	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
GHALPPDB_00259	1.48e-159	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_00260	6.21e-270	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHALPPDB_00261	1.17e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GHALPPDB_00262	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
GHALPPDB_00263	9.86e-153	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GHALPPDB_00264	3.65e-156	-	-	-	-	-	-	-	-
GHALPPDB_00265	2.93e-299	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GHALPPDB_00266	8.72e-313	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GHALPPDB_00267	6.39e-177	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
GHALPPDB_00268	9.15e-302	-	-	-	E	-	-	-	amino acid
GHALPPDB_00269	2.16e-192	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
GHALPPDB_00270	5.67e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
GHALPPDB_00271	7.12e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
GHALPPDB_00272	1.24e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GHALPPDB_00273	5.15e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
GHALPPDB_00274	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GHALPPDB_00275	2.42e-74	-	-	-	-	-	-	-	-
GHALPPDB_00276	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
GHALPPDB_00277	1.68e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
GHALPPDB_00278	1.67e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GHALPPDB_00279	2.07e-65	-	-	-	-	-	-	-	-
GHALPPDB_00280	3.11e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GHALPPDB_00281	3.01e-191	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
GHALPPDB_00282	2.16e-148	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GHALPPDB_00283	5.66e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
GHALPPDB_00284	2.98e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
GHALPPDB_00285	8.79e-67	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GHALPPDB_00286	2.19e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
GHALPPDB_00287	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GHALPPDB_00288	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
GHALPPDB_00289	2.69e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GHALPPDB_00290	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
GHALPPDB_00291	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GHALPPDB_00292	3.15e-67	-	-	-	-	-	-	-	-
GHALPPDB_00293	2.03e-80	-	-	-	-	-	-	-	-
GHALPPDB_00294	5.24e-312	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GHALPPDB_00295	1.56e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
GHALPPDB_00296	9.26e-270	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GHALPPDB_00297	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GHALPPDB_00298	1.42e-76	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GHALPPDB_00299	4.17e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GHALPPDB_00300	1.47e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GHALPPDB_00301	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GHALPPDB_00302	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GHALPPDB_00303	5.78e-63	-	-	-	-	-	-	-	-
GHALPPDB_00304	4.31e-194	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
GHALPPDB_00305	6.95e-184	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
GHALPPDB_00306	9.97e-119	levB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GHALPPDB_00307	1.16e-87	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
GHALPPDB_00310	1.17e-29	repA	-	-	S	-	-	-	Replication initiator protein A
GHALPPDB_00311	5.04e-71	-	-	-	-	-	-	-	-
GHALPPDB_00312	1.56e-132	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
GHALPPDB_00313	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GHALPPDB_00314	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GHALPPDB_00315	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GHALPPDB_00316	7.88e-97	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GHALPPDB_00317	1.76e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHALPPDB_00318	4.1e-118	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
GHALPPDB_00319	2.41e-45	-	-	-	-	-	-	-	-
GHALPPDB_00320	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
GHALPPDB_00321	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GHALPPDB_00322	8.53e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GHALPPDB_00323	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
GHALPPDB_00324	3.82e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GHALPPDB_00325	3.02e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GHALPPDB_00326	1.1e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
GHALPPDB_00327	1.65e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
GHALPPDB_00328	1.82e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
GHALPPDB_00329	1.38e-182	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHALPPDB_00330	3.28e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GHALPPDB_00331	1.43e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
GHALPPDB_00332	5.28e-33	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GHALPPDB_00333	2.66e-29	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GHALPPDB_00334	4.39e-151	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
GHALPPDB_00335	6.16e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GHALPPDB_00336	2.28e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GHALPPDB_00337	2.3e-36	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
GHALPPDB_00338	1.36e-121	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
GHALPPDB_00339	1.02e-143	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
GHALPPDB_00340	1.53e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GHALPPDB_00341	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHALPPDB_00342	3.64e-58	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GHALPPDB_00343	5.33e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GHALPPDB_00344	1.13e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
GHALPPDB_00345	8.08e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GHALPPDB_00346	6.21e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
GHALPPDB_00347	1.9e-195	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GHALPPDB_00348	2.32e-79	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
GHALPPDB_00349	7.51e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GHALPPDB_00350	6.78e-164	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
GHALPPDB_00351	1.51e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
GHALPPDB_00352	1.33e-170	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
GHALPPDB_00353	6.27e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
GHALPPDB_00354	4.95e-246	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GHALPPDB_00355	1.09e-161	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GHALPPDB_00356	3.83e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
GHALPPDB_00357	5.83e-161	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
GHALPPDB_00358	8.44e-24	-	-	-	S	-	-	-	Toxin ToxN, type III toxin-antitoxin system
GHALPPDB_00359	4.69e-32	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00360	2.13e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
GHALPPDB_00361	4.53e-301	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
GHALPPDB_00362	6.39e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GHALPPDB_00363	1.07e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
GHALPPDB_00364	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
GHALPPDB_00365	1.51e-73	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GHALPPDB_00366	1.4e-74	-	-	-	S	-	-	-	Enterocin A Immunity
GHALPPDB_00367	6.48e-173	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
GHALPPDB_00368	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
GHALPPDB_00369	1.59e-206	-	-	-	S	-	-	-	Phospholipase, patatin family
GHALPPDB_00370	2.65e-18	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
GHALPPDB_00371	2.23e-110	-	-	-	S	-	-	-	hydrolase
GHALPPDB_00372	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GHALPPDB_00373	3.43e-184	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
GHALPPDB_00374	1.06e-94	-	-	-	-	-	-	-	-
GHALPPDB_00375	9.32e-112	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
GHALPPDB_00376	2.89e-52	-	-	-	-	-	-	-	-
GHALPPDB_00377	2.85e-23	-	-	-	C	-	-	-	nitroreductase
GHALPPDB_00378	3.57e-34	-	-	-	C	-	-	-	nitroreductase
GHALPPDB_00379	1.29e-312	yhdP	-	-	S	-	-	-	Transporter associated domain
GHALPPDB_00380	5.81e-131	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
GHALPPDB_00381	2.75e-287	-	-	-	E	ko:K03294	-	ko00000	amino acid
GHALPPDB_00382	6.35e-164	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GHALPPDB_00383	3.71e-265	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
GHALPPDB_00384	1.5e-310	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHALPPDB_00386	5.82e-35	-	-	-	-	-	-	-	-
GHALPPDB_00387	3.14e-276	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GHALPPDB_00388	2.04e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
GHALPPDB_00389	5.77e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
GHALPPDB_00390	4.23e-212	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
GHALPPDB_00391	3.93e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
GHALPPDB_00392	1.72e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GHALPPDB_00393	5.86e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
GHALPPDB_00394	1.27e-273	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
GHALPPDB_00395	4.46e-275	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
GHALPPDB_00396	1.62e-62	-	-	-	-	-	-	-	-
GHALPPDB_00397	2.57e-25	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
GHALPPDB_00398	4e-124	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00402	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
GHALPPDB_00403	2.56e-186	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GHALPPDB_00404	1.32e-34	-	-	-	-	-	-	-	-
GHALPPDB_00405	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
GHALPPDB_00406	6.29e-207	-	-	-	L	ko:K07496	-	ko00000	Transposase
GHALPPDB_00407	1.91e-233	-	-	-	S	-	-	-	AAA domain
GHALPPDB_00408	1.98e-163	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHALPPDB_00409	4.73e-31	-	-	-	-	-	-	-	-
GHALPPDB_00410	5.3e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
GHALPPDB_00411	6.64e-162	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
GHALPPDB_00412	3.13e-173	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
GHALPPDB_00413	1.63e-81	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
GHALPPDB_00414	1.22e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
GHALPPDB_00415	3.32e-93	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
GHALPPDB_00416	1.01e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
GHALPPDB_00417	1.87e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GHALPPDB_00418	3.02e-183	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GHALPPDB_00419	5.22e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHALPPDB_00420	1.45e-190	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHALPPDB_00421	2.69e-195	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GHALPPDB_00422	3.16e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
GHALPPDB_00423	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHALPPDB_00424	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GHALPPDB_00425	1.46e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GHALPPDB_00426	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
GHALPPDB_00427	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GHALPPDB_00428	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GHALPPDB_00429	7.24e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GHALPPDB_00430	1.73e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
GHALPPDB_00431	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
GHALPPDB_00432	2.63e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GHALPPDB_00433	1.05e-72	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GHALPPDB_00434	5.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GHALPPDB_00435	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GHALPPDB_00436	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GHALPPDB_00437	2.9e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GHALPPDB_00438	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GHALPPDB_00439	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GHALPPDB_00440	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GHALPPDB_00441	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
GHALPPDB_00442	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GHALPPDB_00443	3.03e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GHALPPDB_00444	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GHALPPDB_00445	2.94e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GHALPPDB_00446	1.91e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GHALPPDB_00447	3.16e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GHALPPDB_00448	2.23e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
GHALPPDB_00449	3.29e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GHALPPDB_00450	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
GHALPPDB_00451	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GHALPPDB_00452	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GHALPPDB_00453	7.28e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GHALPPDB_00454	1.56e-156	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
GHALPPDB_00455	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHALPPDB_00456	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GHALPPDB_00457	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
GHALPPDB_00458	7.84e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
GHALPPDB_00462	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
GHALPPDB_00463	9.65e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GHALPPDB_00464	5.97e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GHALPPDB_00465	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GHALPPDB_00466	2.32e-305	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GHALPPDB_00467	3.8e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
GHALPPDB_00468	6.18e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
GHALPPDB_00469	1.26e-46	yabO	-	-	J	-	-	-	S4 domain protein
GHALPPDB_00470	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GHALPPDB_00471	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GHALPPDB_00472	3.42e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GHALPPDB_00473	8.34e-165	-	-	-	S	-	-	-	(CBS) domain
GHALPPDB_00474	1.04e-119	-	-	-	K	-	-	-	transcriptional regulator
GHALPPDB_00475	7.68e-275	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GHALPPDB_00476	1.33e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GHALPPDB_00477	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GHALPPDB_00478	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GHALPPDB_00479	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
GHALPPDB_00480	4.49e-194	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GHALPPDB_00481	0.0	-	-	-	E	-	-	-	amino acid
GHALPPDB_00482	9.39e-85	-	-	-	-	-	-	-	-
GHALPPDB_00483	2.95e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
GHALPPDB_00484	5.21e-164	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GHALPPDB_00485	3.61e-178	-	-	-	K	-	-	-	Helix-turn-helix domain
GHALPPDB_00486	7.99e-294	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GHALPPDB_00487	8.68e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
GHALPPDB_00488	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GHALPPDB_00489	2.95e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GHALPPDB_00490	5.05e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
GHALPPDB_00491	6.53e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
GHALPPDB_00492	4.53e-55	-	-	-	-	-	-	-	-
GHALPPDB_00493	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
GHALPPDB_00494	6.85e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
GHALPPDB_00495	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
GHALPPDB_00496	4.39e-66	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
GHALPPDB_00497	7.96e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
GHALPPDB_00498	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
GHALPPDB_00499	4.95e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
GHALPPDB_00500	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GHALPPDB_00501	8.2e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GHALPPDB_00502	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GHALPPDB_00503	1.54e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHALPPDB_00504	4.97e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GHALPPDB_00505	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GHALPPDB_00506	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
GHALPPDB_00507	2.15e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GHALPPDB_00508	7.56e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GHALPPDB_00509	2.42e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GHALPPDB_00510	7.36e-234	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GHALPPDB_00511	4.94e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
GHALPPDB_00512	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
GHALPPDB_00515	2.36e-247	ampC	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_00516	4.84e-50	-	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_00517	5.35e-159	-	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_00518	1.89e-19	-	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_00519	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
GHALPPDB_00520	1.3e-139	vanZ	-	-	V	-	-	-	VanZ like family
GHALPPDB_00521	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GHALPPDB_00522	0.0	yclK	-	-	T	-	-	-	Histidine kinase
GHALPPDB_00523	4.46e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
GHALPPDB_00524	5.73e-80	-	-	-	S	-	-	-	SdpI/YhfL protein family
GHALPPDB_00525	9.25e-221	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
GHALPPDB_00526	3.87e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
GHALPPDB_00527	1.64e-40	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
GHALPPDB_00528	2.64e-50	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
GHALPPDB_00530	3.05e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHALPPDB_00531	4.89e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
GHALPPDB_00532	9.9e-105	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
GHALPPDB_00533	1.18e-55	-	-	-	-	-	-	-	-
GHALPPDB_00534	2.04e-95	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
GHALPPDB_00535	6.9e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
GHALPPDB_00536	1.86e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
GHALPPDB_00537	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
GHALPPDB_00538	2.3e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
GHALPPDB_00539	9.51e-119	-	-	-	S	-	-	-	VanZ like family
GHALPPDB_00541	0.0	-	-	-	E	-	-	-	Amino acid permease
GHALPPDB_00542	9.83e-235	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
GHALPPDB_00543	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GHALPPDB_00544	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GHALPPDB_00545	1.14e-175	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
GHALPPDB_00546	3.38e-273	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GHALPPDB_00547	2.06e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GHALPPDB_00548	3.74e-153	-	-	-	-	-	-	-	-
GHALPPDB_00549	8.04e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GHALPPDB_00550	2.4e-191	-	-	-	S	-	-	-	hydrolase
GHALPPDB_00551	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GHALPPDB_00552	2.51e-216	ybbR	-	-	S	-	-	-	YbbR-like protein
GHALPPDB_00553	5.87e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GHALPPDB_00554	3.71e-261	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GHALPPDB_00555	3.09e-178	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_00556	5.95e-176	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_00557	9.1e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GHALPPDB_00558	1.71e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
GHALPPDB_00559	7.47e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
GHALPPDB_00560	1.87e-118	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
GHALPPDB_00561	5.23e-231	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
GHALPPDB_00562	7.79e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GHALPPDB_00563	1.15e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
GHALPPDB_00564	3.58e-124	-	-	-	-	-	-	-	-
GHALPPDB_00565	2.71e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GHALPPDB_00566	6.01e-288	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
GHALPPDB_00567	1.16e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GHALPPDB_00568	6.71e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
GHALPPDB_00570	2.76e-68	-	-	-	-	-	-	-	-
GHALPPDB_00571	2.99e-82	-	-	-	-	-	-	-	-
GHALPPDB_00572	1.04e-150	-	-	-	-	-	-	-	-
GHALPPDB_00573	0.0	ycaM	-	-	E	-	-	-	amino acid
GHALPPDB_00574	8.38e-192	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GHALPPDB_00575	0.0	-	-	-	S	-	-	-	SH3-like domain
GHALPPDB_00576	4.53e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GHALPPDB_00577	8.23e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
GHALPPDB_00578	1.27e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
GHALPPDB_00579	2.09e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
GHALPPDB_00580	7.57e-109	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
GHALPPDB_00581	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GHALPPDB_00582	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GHALPPDB_00583	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
GHALPPDB_00584	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
GHALPPDB_00585	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GHALPPDB_00586	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
GHALPPDB_00587	1.28e-276	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
GHALPPDB_00588	6.74e-267	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GHALPPDB_00589	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GHALPPDB_00590	9.89e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GHALPPDB_00591	8.57e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GHALPPDB_00592	5.48e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
GHALPPDB_00593	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GHALPPDB_00594	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
GHALPPDB_00595	4.56e-138	-	-	-	S	ko:K06872	-	ko00000	TPM domain
GHALPPDB_00596	5.22e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
GHALPPDB_00597	3.34e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
GHALPPDB_00598	6.01e-147	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
GHALPPDB_00600	6.33e-148	-	-	-	-	-	-	-	-
GHALPPDB_00601	9.44e-99	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHALPPDB_00602	2.05e-94	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
GHALPPDB_00603	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
GHALPPDB_00604	5.37e-221	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GHALPPDB_00605	3.02e-253	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GHALPPDB_00606	1.07e-237	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GHALPPDB_00607	6.08e-188	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GHALPPDB_00608	1.21e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GHALPPDB_00609	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
GHALPPDB_00610	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
GHALPPDB_00611	7.92e-151	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GHALPPDB_00612	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
GHALPPDB_00614	3.32e-37	-	-	-	-	-	-	-	-
GHALPPDB_00615	6.27e-24	-	-	-	-	-	-	-	-
GHALPPDB_00616	1.04e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GHALPPDB_00617	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
GHALPPDB_00618	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
GHALPPDB_00619	2.52e-142	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GHALPPDB_00620	8.94e-252	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GHALPPDB_00621	3.8e-130	-	-	-	G	-	-	-	Aldose 1-epimerase
GHALPPDB_00622	2.12e-77	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
GHALPPDB_00623	9.69e-72	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
GHALPPDB_00624	1.61e-138	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
GHALPPDB_00625	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GHALPPDB_00626	2.48e-64	ydhF	-	-	S	-	-	-	Aldo keto reductase
GHALPPDB_00627	9.89e-35	ydhF	-	-	S	-	-	-	Aldo keto reductase
GHALPPDB_00628	3.48e-36	ydhF	-	-	S	-	-	-	Aldo keto reductase
GHALPPDB_00629	3.96e-74	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
GHALPPDB_00630	6.22e-127	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
GHALPPDB_00631	2.6e-107	-	-	-	-	-	-	-	-
GHALPPDB_00632	2.91e-47	-	-	-	C	-	-	-	FMN_bind
GHALPPDB_00633	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
GHALPPDB_00634	1.43e-134	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
GHALPPDB_00635	1.06e-260	pbpX1	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_00636	1.43e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GHALPPDB_00637	3.01e-272	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GHALPPDB_00638	3.67e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GHALPPDB_00639	3.65e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GHALPPDB_00640	2.32e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GHALPPDB_00641	2.94e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GHALPPDB_00642	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GHALPPDB_00643	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GHALPPDB_00644	5.52e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GHALPPDB_00645	0.0	potE	-	-	E	-	-	-	Amino Acid
GHALPPDB_00646	1.31e-135	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
GHALPPDB_00647	5.7e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GHALPPDB_00648	1.6e-278	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GHALPPDB_00649	6.72e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GHALPPDB_00650	1.98e-193	-	-	-	-	-	-	-	-
GHALPPDB_00651	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHALPPDB_00652	1.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GHALPPDB_00653	6.62e-163	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_00654	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
GHALPPDB_00655	1.17e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GHALPPDB_00656	4.67e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GHALPPDB_00657	2.36e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
GHALPPDB_00658	1.64e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GHALPPDB_00659	5.68e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
GHALPPDB_00660	1.32e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GHALPPDB_00661	1.56e-152	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
GHALPPDB_00662	5.3e-189	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
GHALPPDB_00663	1.15e-144	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GHALPPDB_00664	1.85e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
GHALPPDB_00665	6.43e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
GHALPPDB_00666	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GHALPPDB_00667	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GHALPPDB_00668	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GHALPPDB_00669	9.59e-289	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
GHALPPDB_00670	1.46e-145	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
GHALPPDB_00671	4.99e-252	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
GHALPPDB_00672	1.1e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
GHALPPDB_00673	2.15e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GHALPPDB_00674	2.38e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
GHALPPDB_00675	8.57e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GHALPPDB_00676	2.23e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GHALPPDB_00677	1.62e-189	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
GHALPPDB_00678	9.05e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
GHALPPDB_00679	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GHALPPDB_00680	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GHALPPDB_00682	1.52e-238	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
GHALPPDB_00683	2.99e-180	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
GHALPPDB_00684	3.37e-220	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
GHALPPDB_00685	9.25e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
GHALPPDB_00686	2.36e-93	-	-	-	K	-	-	-	Transcriptional regulator
GHALPPDB_00687	4.68e-110	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GHALPPDB_00688	1.11e-299	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
GHALPPDB_00689	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
GHALPPDB_00690	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GHALPPDB_00691	1.48e-21	-	-	-	-	-	-	-	-
GHALPPDB_00692	3.29e-127	-	-	-	E	-	-	-	amino acid
GHALPPDB_00693	3.3e-55	-	-	-	-	-	-	-	-
GHALPPDB_00694	1e-113	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GHALPPDB_00695	1.01e-102	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
GHALPPDB_00696	5.06e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHALPPDB_00697	1.75e-137	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
GHALPPDB_00698	1.85e-48	-	-	-	-	-	-	-	-
GHALPPDB_00699	1.77e-93	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
GHALPPDB_00700	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
GHALPPDB_00701	0.0	-	-	-	S	-	-	-	TerB-C domain
GHALPPDB_00702	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
GHALPPDB_00703	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
GHALPPDB_00704	4.75e-80	-	-	-	-	-	-	-	-
GHALPPDB_00705	6.62e-178	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
GHALPPDB_00706	4.49e-50	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GHALPPDB_00709	1.18e-165	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
GHALPPDB_00710	6.72e-289	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GHALPPDB_00711	3.55e-149	-	-	-	-	-	-	-	-
GHALPPDB_00712	2.91e-99	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
GHALPPDB_00713	2.15e-280	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
GHALPPDB_00714	1.45e-92	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
GHALPPDB_00715	1.01e-24	-	-	-	-	-	-	-	-
GHALPPDB_00716	4.46e-190	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
GHALPPDB_00717	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_00718	1.8e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
GHALPPDB_00719	2.72e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1828
GHALPPDB_00720	2.48e-69	-	-	-	-	-	-	-	-
GHALPPDB_00721	2.82e-214	citR	-	-	K	-	-	-	Putative sugar-binding domain
GHALPPDB_00722	1.38e-309	-	-	-	S	-	-	-	Putative threonine/serine exporter
GHALPPDB_00723	1.42e-123	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
GHALPPDB_00724	3.71e-34	-	-	-	-	ko:K14201	ko05150,map05150	ko00000,ko00001	-
GHALPPDB_00726	3.91e-26	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GHALPPDB_00728	1.52e-114	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GHALPPDB_00729	7.07e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
GHALPPDB_00730	8.96e-79	-	-	-	-	-	-	-	-
GHALPPDB_00731	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GHALPPDB_00732	1.43e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GHALPPDB_00733	4.28e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
GHALPPDB_00734	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GHALPPDB_00735	4.39e-281	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
GHALPPDB_00737	1.24e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GHALPPDB_00738	1.67e-105	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GHALPPDB_00739	6.3e-308	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
GHALPPDB_00740	5.71e-192	-	-	-	S	-	-	-	Putative ABC-transporter type IV
GHALPPDB_00741	3.65e-128	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
GHALPPDB_00742	6.12e-112	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
GHALPPDB_00743	4.63e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
GHALPPDB_00744	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
GHALPPDB_00745	3.31e-221	ydbI	-	-	K	-	-	-	AI-2E family transporter
GHALPPDB_00746	1.08e-131	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
GHALPPDB_00747	4.97e-24	-	-	-	-	-	-	-	-
GHALPPDB_00748	3.14e-53	-	-	-	-	-	-	-	-
GHALPPDB_00749	4.93e-166	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_00750	2.25e-166	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
GHALPPDB_00751	1.78e-218	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
GHALPPDB_00752	6.34e-172	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
GHALPPDB_00753	0.0	fusA1	-	-	J	-	-	-	elongation factor G
GHALPPDB_00754	2.03e-184	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
GHALPPDB_00755	5.85e-38	-	-	-	-	-	-	-	-
GHALPPDB_00756	6.49e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHALPPDB_00757	3.77e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
GHALPPDB_00758	1.03e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
GHALPPDB_00759	2.12e-43	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
GHALPPDB_00760	6.11e-262	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
GHALPPDB_00761	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
GHALPPDB_00762	2.55e-246	pbpX1	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_00763	8.45e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
GHALPPDB_00764	9.99e-12	-	-	-	-	-	-	-	-
GHALPPDB_00765	3.2e-201	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GHALPPDB_00766	7.77e-166	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
GHALPPDB_00767	2.22e-165	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
GHALPPDB_00768	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
GHALPPDB_00769	1.31e-295	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
GHALPPDB_00770	4.56e-120	-	-	-	-	-	-	-	-
GHALPPDB_00771	2.7e-154	-	-	-	-	-	-	-	-
GHALPPDB_00772	3.36e-137	-	-	-	-	-	-	-	-
GHALPPDB_00773	1.05e-162	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
GHALPPDB_00774	1.79e-92	-	-	-	O	-	-	-	OsmC-like protein
GHALPPDB_00775	1.07e-263	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GHALPPDB_00776	2.78e-71	sptS	-	-	T	-	-	-	Histidine kinase
GHALPPDB_00777	7.85e-156	sptS	-	-	T	-	-	-	Histidine kinase
GHALPPDB_00778	1.02e-103	dltr	-	-	K	-	-	-	response regulator
GHALPPDB_00779	3.81e-66	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00780	1.96e-23	-	-	-	-	-	-	-	-
GHALPPDB_00781	3.06e-74	-	-	-	-	-	-	-	-
GHALPPDB_00782	2.44e-183	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00783	3.61e-13	sagB	-	-	C	-	-	-	coenzyme F420-1:gamma-L-glutamate ligase activity
GHALPPDB_00789	3.68e-261	-	-	-	V	-	-	-	ABC transporter transmembrane region
GHALPPDB_00792	1.03e-49	-	-	-	-	-	-	-	-
GHALPPDB_00793	1.18e-140	-	-	-	K	-	-	-	WHG domain
GHALPPDB_00794	1.14e-123	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
GHALPPDB_00795	1.05e-125	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
GHALPPDB_00796	4.51e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GHALPPDB_00797	6.37e-231	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GHALPPDB_00798	2.12e-114	cvpA	-	-	S	-	-	-	Colicin V production protein
GHALPPDB_00799	9.37e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
GHALPPDB_00800	3.14e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GHALPPDB_00801	2.77e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
GHALPPDB_00802	2.29e-196	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
GHALPPDB_00803	1.83e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
GHALPPDB_00804	1.97e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GHALPPDB_00805	2.2e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
GHALPPDB_00806	4.53e-69	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_00807	2.51e-298	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_00808	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
GHALPPDB_00809	1.18e-156	vanR	-	-	K	-	-	-	response regulator
GHALPPDB_00810	2.09e-266	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
GHALPPDB_00811	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GHALPPDB_00812	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GHALPPDB_00813	8.82e-108	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_00814	1.16e-129	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
GHALPPDB_00815	1.95e-45	-	-	-	S	-	-	-	Enterocin A Immunity
GHALPPDB_00816	8.68e-46	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
GHALPPDB_00817	8.68e-44	-	-	-	-	-	-	-	-
GHALPPDB_00818	1.13e-21	-	-	-	-	-	-	-	-
GHALPPDB_00819	7.77e-36	-	-	-	-	-	-	-	-
GHALPPDB_00820	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
GHALPPDB_00821	3.33e-84	-	-	-	S	-	-	-	CAAX protease self-immunity
GHALPPDB_00822	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
GHALPPDB_00823	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GHALPPDB_00824	4.08e-47	-	-	-	-	-	-	-	-
GHALPPDB_00825	4.88e-131	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_00826	1.46e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GHALPPDB_00827	3.21e-208	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GHALPPDB_00828	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
GHALPPDB_00829	2.08e-21	ps301	-	-	K	-	-	-	sequence-specific DNA binding
GHALPPDB_00830	1.92e-123	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GHALPPDB_00831	1.3e-239	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GHALPPDB_00832	2.72e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
GHALPPDB_00834	5.43e-48	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GHALPPDB_00835	2.94e-117	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GHALPPDB_00836	1.26e-126	-	-	-	I	-	-	-	PAP2 superfamily
GHALPPDB_00837	3.59e-164	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
GHALPPDB_00838	1.23e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHALPPDB_00839	2.3e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
GHALPPDB_00840	3.93e-109	yfhC	-	-	C	-	-	-	nitroreductase
GHALPPDB_00841	3.61e-157	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
GHALPPDB_00842	9.89e-278	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GHALPPDB_00843	8.42e-85	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GHALPPDB_00844	1.88e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
GHALPPDB_00845	6.67e-40	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
GHALPPDB_00846	6.29e-307	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHALPPDB_00847	9.69e-100	-	-	-	-	-	-	-	-
GHALPPDB_00848	6.04e-200	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
GHALPPDB_00849	2.53e-195	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
GHALPPDB_00850	3.51e-12	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
GHALPPDB_00851	9.13e-283	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GHALPPDB_00852	5.18e-250	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GHALPPDB_00853	8.47e-188	epsB	-	-	M	-	-	-	biosynthesis protein
GHALPPDB_00854	1.47e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
GHALPPDB_00855	1.15e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
GHALPPDB_00856	2.32e-155	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
GHALPPDB_00857	1.21e-108	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
GHALPPDB_00858	5.09e-100	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
GHALPPDB_00859	1.92e-182	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GHALPPDB_00860	1.28e-61	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
GHALPPDB_00861	4.66e-101	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
GHALPPDB_00862	9.57e-86	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
GHALPPDB_00863	3.82e-44	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
GHALPPDB_00864	1.83e-47	-	-	-	-	-	-	-	-
GHALPPDB_00865	4.48e-161	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
GHALPPDB_00866	1.63e-27	-	-	-	E	-	-	-	Hexapeptide repeat of succinyl-transferase
GHALPPDB_00867	7.32e-307	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_00868	1.38e-20	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
GHALPPDB_00869	5.6e-19	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
GHALPPDB_00870	7.84e-302	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_00872	5.69e-195	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
GHALPPDB_00873	7.43e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
GHALPPDB_00874	2.03e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
GHALPPDB_00875	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
GHALPPDB_00876	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GHALPPDB_00877	4.52e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GHALPPDB_00879	5.13e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
GHALPPDB_00880	1.37e-306	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GHALPPDB_00881	1.17e-146	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_00882	2.71e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
GHALPPDB_00883	4.08e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_00884	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_00885	9.06e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GHALPPDB_00886	1.09e-170	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_00887	5.33e-288	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_00888	1.19e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
GHALPPDB_00889	7.47e-229	-	-	-	EGP	-	-	-	Major facilitator superfamily
GHALPPDB_00890	1.41e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
GHALPPDB_00891	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
GHALPPDB_00892	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_00893	1.25e-104	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
GHALPPDB_00894	1.23e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
GHALPPDB_00895	2.62e-166	-	-	-	F	-	-	-	glutamine amidotransferase
GHALPPDB_00896	6.54e-117	-	-	-	-	-	-	-	-
GHALPPDB_00897	3.97e-40	-	-	-	-	-	-	-	-
GHALPPDB_00898	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
GHALPPDB_00899	7.25e-265	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
GHALPPDB_00900	2.3e-275	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
GHALPPDB_00901	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_00902	5.44e-116	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GHALPPDB_00903	4.2e-301	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
GHALPPDB_00904	3.04e-180	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
GHALPPDB_00905	3.68e-270	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_00906	6.16e-243	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_00907	1.21e-179	-	-	-	S	-	-	-	Bacteriocin helveticin-J
GHALPPDB_00908	3.8e-21	-	-	-	S	-	-	-	Bacteriocin helveticin-J
GHALPPDB_00909	2.51e-203	-	-	-	-	-	-	-	-
GHALPPDB_00910	1.25e-97	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GHALPPDB_00911	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
GHALPPDB_00912	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GHALPPDB_00913	4.13e-313	qacA	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_00918	1.04e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GHALPPDB_00921	6.5e-38	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
GHALPPDB_00923	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GHALPPDB_00924	3.51e-308	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
GHALPPDB_00925	3.03e-60	-	-	-	-	-	-	-	-
GHALPPDB_00926	4.23e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
GHALPPDB_00927	5.08e-143	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
GHALPPDB_00928	2.65e-217	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
GHALPPDB_00929	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHALPPDB_00930	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GHALPPDB_00931	2.94e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GHALPPDB_00932	2e-264	camS	-	-	S	-	-	-	sex pheromone
GHALPPDB_00933	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GHALPPDB_00934	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
GHALPPDB_00935	2.18e-138	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
GHALPPDB_00937	1.06e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
GHALPPDB_00938	4.89e-176	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
GHALPPDB_00939	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GHALPPDB_00940	6.32e-288	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GHALPPDB_00941	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GHALPPDB_00942	3.85e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GHALPPDB_00943	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GHALPPDB_00944	5.87e-256	-	-	-	M	-	-	-	Glycosyl transferases group 1
GHALPPDB_00945	8.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GHALPPDB_00946	2.37e-242	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_00947	3.41e-80	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
GHALPPDB_00948	1.49e-157	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
GHALPPDB_00949	2.37e-271	-	-	-	-	-	-	-	-
GHALPPDB_00952	2.88e-119	-	-	-	-	-	-	-	-
GHALPPDB_00953	3.23e-138	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
GHALPPDB_00954	2.41e-31	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
GHALPPDB_00956	1.53e-102	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
GHALPPDB_00957	1.78e-218	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
GHALPPDB_00958	9.44e-169	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
GHALPPDB_00959	1.5e-150	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
GHALPPDB_00960	1.25e-128	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
GHALPPDB_00961	2.77e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
GHALPPDB_00962	1.13e-248	-	-	-	D	-	-	-	nuclear chromosome segregation
GHALPPDB_00963	8.58e-126	-	-	-	M	-	-	-	LysM domain protein
GHALPPDB_00964	5.26e-19	-	-	-	-	-	-	-	-
GHALPPDB_00965	3.17e-30	-	3.2.1.4	GH5,GH9	M	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	domain protein
GHALPPDB_00966	2.59e-86	-	-	-	L	-	-	-	Transposase
GHALPPDB_00967	2.87e-53	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
GHALPPDB_00968	4.43e-105	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
GHALPPDB_00969	4.92e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
GHALPPDB_00970	1.81e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
GHALPPDB_00971	6.74e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GHALPPDB_00972	1.3e-202	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_00973	9.06e-156	-	-	-	L	-	-	-	Transposase DDE domain
GHALPPDB_00974	3.96e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GHALPPDB_00975	3.37e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GHALPPDB_00976	5.94e-127	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
GHALPPDB_00977	2.18e-172	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
GHALPPDB_00978	5.89e-234	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GHALPPDB_00979	6.36e-26	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
GHALPPDB_00980	8.02e-129	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GHALPPDB_00981	7.9e-287	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
GHALPPDB_00982	6.39e-90	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GHALPPDB_00983	3.03e-277	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
GHALPPDB_00984	1.02e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, C-terminal domain
GHALPPDB_00985	5.74e-38	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_00986	7.02e-34	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_00987	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
GHALPPDB_00988	2.54e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GHALPPDB_00989	1.4e-179	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
GHALPPDB_00992	2.03e-279	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_00993	7.64e-62	-	-	-	-	-	-	-	-
GHALPPDB_00994	3.67e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
GHALPPDB_00995	1.63e-118	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
GHALPPDB_00996	1.5e-32	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
GHALPPDB_00997	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
GHALPPDB_00998	7.22e-262	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
GHALPPDB_00999	1.1e-276	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GHALPPDB_01000	3.65e-16	-	-	-	K	-	-	-	DNA-templated transcription, initiation
GHALPPDB_01001	8.72e-12	-	-	-	K	-	-	-	DNA-templated transcription, initiation
GHALPPDB_01003	5.71e-206	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01004	4.3e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
GHALPPDB_01005	7.02e-40	-	-	-	-	-	-	-	-
GHALPPDB_01006	8.86e-09	-	-	-	-	-	-	-	-
GHALPPDB_01008	1.63e-112	-	-	-	-	-	-	-	-
GHALPPDB_01009	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
GHALPPDB_01010	1.28e-50	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_01011	2.18e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GHALPPDB_01012	2.54e-286	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
GHALPPDB_01013	1.16e-204	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
GHALPPDB_01014	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GHALPPDB_01015	1.57e-97	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
GHALPPDB_01016	3e-309	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GHALPPDB_01017	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GHALPPDB_01018	4.53e-98	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GHALPPDB_01019	3.92e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
GHALPPDB_01020	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
GHALPPDB_01021	5.78e-57	-	-	-	-	-	-	-	-
GHALPPDB_01022	4.99e-189	-	-	-	GK	-	-	-	ROK family
GHALPPDB_01023	3.64e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHALPPDB_01024	6.43e-270	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01025	5.42e-293	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_01026	2.84e-33	-	-	-	-	-	-	-	-
GHALPPDB_01027	1.14e-123	-	-	-	-	-	-	-	-
GHALPPDB_01028	1.35e-135	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01029	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GHALPPDB_01030	8.69e-192	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
GHALPPDB_01031	2.02e-52	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
GHALPPDB_01032	2.59e-31	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_01033	3.23e-289	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
GHALPPDB_01034	8.23e-222	-	-	-	-	-	-	-	-
GHALPPDB_01035	2.79e-77	lysM	-	-	M	-	-	-	LysM domain
GHALPPDB_01037	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
GHALPPDB_01038	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
GHALPPDB_01039	1.58e-33	-	-	-	-	-	-	-	-
GHALPPDB_01040	3.64e-237	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GHALPPDB_01041	1.22e-256	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_01042	1.53e-108	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
GHALPPDB_01043	7.81e-155	-	-	-	-	-	-	-	-
GHALPPDB_01044	6.89e-182	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
GHALPPDB_01045	1.14e-179	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
GHALPPDB_01046	2.86e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
GHALPPDB_01047	9.84e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GHALPPDB_01048	3.36e-230	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
GHALPPDB_01049	3.81e-151	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01050	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GHALPPDB_01051	1.74e-87	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
GHALPPDB_01052	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
GHALPPDB_01053	1.26e-101	-	-	-	C	-	-	-	Flavodoxin
GHALPPDB_01054	9.85e-147	-	-	-	I	-	-	-	Acid phosphatase homologues
GHALPPDB_01055	8.48e-145	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
GHALPPDB_01056	2.52e-263	-	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_01057	3.04e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
GHALPPDB_01058	3.35e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
GHALPPDB_01059	1.18e-293	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
GHALPPDB_01060	3.35e-74	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
GHALPPDB_01061	1.58e-202	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
GHALPPDB_01062	0.0	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GHALPPDB_01063	9.66e-46	-	-	-	-	-	-	-	-
GHALPPDB_01064	5.03e-20	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GHALPPDB_01065	4.35e-31	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
GHALPPDB_01066	1.63e-79	-	-	-	-	-	-	-	-
GHALPPDB_01067	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
GHALPPDB_01068	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
GHALPPDB_01069	1.94e-125	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
GHALPPDB_01070	3.06e-77	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
GHALPPDB_01073	1.37e-214	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GHALPPDB_01076	5.04e-278	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GHALPPDB_01077	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_01078	4.22e-186	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GHALPPDB_01079	2.45e-151	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
GHALPPDB_01080	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
GHALPPDB_01081	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
GHALPPDB_01082	9.71e-228	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
GHALPPDB_01083	2.96e-30	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
GHALPPDB_01084	2.74e-81	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
GHALPPDB_01085	6.68e-29	-	-	-	-	-	-	-	-
GHALPPDB_01086	1.04e-76	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
GHALPPDB_01087	8.05e-149	-	-	-	K	-	-	-	Rhodanese Homology Domain
GHALPPDB_01088	4.43e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GHALPPDB_01089	4.81e-21	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
GHALPPDB_01090	2.26e-17	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
GHALPPDB_01091	1.94e-55	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
GHALPPDB_01092	6.11e-37	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GHALPPDB_01093	2.31e-79	-	-	-	M	-	-	-	the current gene model (or a revised gene model) may contain a
GHALPPDB_01094	0.0	-	-	-	L	-	-	-	Transposase
GHALPPDB_01095	2.44e-25	-	-	-	-	-	-	-	-
GHALPPDB_01096	2.02e-29	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
GHALPPDB_01097	2.9e-69	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01098	1.38e-121	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01100	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GHALPPDB_01101	2.77e-30	-	-	-	-	-	-	-	-
GHALPPDB_01102	5.7e-44	-	-	-	-	-	-	-	-
GHALPPDB_01103	4.13e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
GHALPPDB_01104	9.35e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
GHALPPDB_01105	9.75e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01106	2.63e-207	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
GHALPPDB_01107	2.27e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GHALPPDB_01108	3.15e-198	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
GHALPPDB_01109	3.41e-152	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
GHALPPDB_01110	3.36e-61	-	-	-	-	-	-	-	-
GHALPPDB_01111	3.66e-123	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
GHALPPDB_01112	9.89e-64	-	-	-	-	-	-	-	-
GHALPPDB_01113	5.11e-258	-	-	-	G	-	-	-	Major Facilitator Superfamily
GHALPPDB_01114	2.26e-68	-	-	-	-	-	-	-	-
GHALPPDB_01115	1.04e-61	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
GHALPPDB_01117	4.15e-179	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
GHALPPDB_01118	6.34e-201	-	-	-	-	-	-	-	-
GHALPPDB_01119	1.03e-207	-	-	-	-	-	-	-	-
GHALPPDB_01120	1.63e-173	-	-	-	-	-	-	-	-
GHALPPDB_01121	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
GHALPPDB_01122	7.4e-89	ynbB	-	-	P	-	-	-	aluminum resistance
GHALPPDB_01123	1.58e-109	ynbB	-	-	P	-	-	-	aluminum resistance
GHALPPDB_01124	4.76e-61	ynbB	-	-	P	-	-	-	aluminum resistance
GHALPPDB_01125	3.23e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GHALPPDB_01126	7.04e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
GHALPPDB_01127	2.45e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
GHALPPDB_01128	1.42e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
GHALPPDB_01129	3.12e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GHALPPDB_01130	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
GHALPPDB_01131	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
GHALPPDB_01132	2.32e-203	-	-	-	S	-	-	-	membrane
GHALPPDB_01133	0.0	-	-	-	S	-	-	-	membrane
GHALPPDB_01134	5.79e-217	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
GHALPPDB_01135	2.03e-170	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
GHALPPDB_01136	2.53e-31	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
GHALPPDB_01137	8.2e-102	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GHALPPDB_01138	2.06e-103	-	-	-	K	-	-	-	Transcriptional regulator
GHALPPDB_01139	3.02e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GHALPPDB_01140	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHALPPDB_01141	1.66e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
GHALPPDB_01142	1.8e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
GHALPPDB_01143	8.97e-293	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GHALPPDB_01144	5.23e-102	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GHALPPDB_01145	1.64e-94	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
GHALPPDB_01146	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
GHALPPDB_01147	5.09e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GHALPPDB_01148	7.44e-183	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
GHALPPDB_01149	8.96e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
GHALPPDB_01150	2.25e-241	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GHALPPDB_01151	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
GHALPPDB_01152	1.23e-237	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_01153	2.19e-124	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
GHALPPDB_01154	7.67e-234	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
GHALPPDB_01155	3.44e-57	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHALPPDB_01156	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
GHALPPDB_01157	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
GHALPPDB_01158	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
GHALPPDB_01159	2.04e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
GHALPPDB_01160	3.19e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GHALPPDB_01161	1.02e-277	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
GHALPPDB_01162	2.4e-312	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GHALPPDB_01163	3.99e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_01164	9.3e-56	ymdB	-	-	S	-	-	-	Macro domain protein
GHALPPDB_01165	7.07e-38	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
GHALPPDB_01167	6.51e-83	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GHALPPDB_01168	1.07e-294	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GHALPPDB_01169	2.79e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
GHALPPDB_01170	1.51e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GHALPPDB_01171	1.54e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
GHALPPDB_01172	3.58e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GHALPPDB_01173	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
GHALPPDB_01174	5.96e-146	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GHALPPDB_01175	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
GHALPPDB_01176	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
GHALPPDB_01177	6.04e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
GHALPPDB_01178	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
GHALPPDB_01179	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
GHALPPDB_01180	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
GHALPPDB_01181	5.73e-210	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
GHALPPDB_01182	1.18e-227	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
GHALPPDB_01183	1.1e-259	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
GHALPPDB_01184	2.7e-233	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GHALPPDB_01185	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
GHALPPDB_01186	3.38e-226	-	-	-	-	-	-	-	-
GHALPPDB_01187	9.13e-182	-	-	-	-	-	-	-	-
GHALPPDB_01188	2.67e-136	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
GHALPPDB_01189	7.83e-38	-	-	-	-	-	-	-	-
GHALPPDB_01190	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
GHALPPDB_01191	3.13e-173	-	-	-	-	-	-	-	-
GHALPPDB_01192	1.36e-179	-	-	-	-	-	-	-	-
GHALPPDB_01193	8.47e-181	-	-	-	-	-	-	-	-
GHALPPDB_01194	1.81e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
GHALPPDB_01195	7.06e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
GHALPPDB_01196	4.94e-308	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
GHALPPDB_01197	4.9e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GHALPPDB_01198	2.49e-158	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
GHALPPDB_01199	6.48e-89	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
GHALPPDB_01200	1.4e-159	-	-	-	S	-	-	-	Peptidase family M23
GHALPPDB_01201	7.08e-252	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GHALPPDB_01202	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GHALPPDB_01203	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
GHALPPDB_01204	5.4e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
GHALPPDB_01205	1.09e-172	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
GHALPPDB_01206	1.48e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GHALPPDB_01207	2.33e-125	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GHALPPDB_01208	2.03e-223	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
GHALPPDB_01209	1.21e-89	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
GHALPPDB_01210	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
GHALPPDB_01211	7.77e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GHALPPDB_01212	4.2e-115	-	-	-	S	-	-	-	Peptidase family M23
GHALPPDB_01213	6.96e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GHALPPDB_01214	6.82e-138	-	-	-	-	-	-	-	-
GHALPPDB_01215	1.11e-50	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GHALPPDB_01216	9.16e-80	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GHALPPDB_01217	5.13e-05	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GHALPPDB_01218	3.33e-30	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
GHALPPDB_01219	4.13e-154	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
GHALPPDB_01220	2.62e-307	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
GHALPPDB_01221	2.15e-72	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GHALPPDB_01222	2.22e-157	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
GHALPPDB_01223	6.4e-131	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
GHALPPDB_01224	1.55e-18	-	-	-	-	-	-	-	-
GHALPPDB_01225	2.13e-77	-	-	-	-	-	-	-	-
GHALPPDB_01226	5.96e-135	-	-	-	K	-	-	-	LysR substrate binding domain
GHALPPDB_01227	6.5e-26	-	-	-	-	-	-	-	-
GHALPPDB_01228	1.68e-275	-	-	-	S	-	-	-	Sterol carrier protein domain
GHALPPDB_01229	2.22e-125	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
GHALPPDB_01230	3.13e-208	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
GHALPPDB_01231	7.26e-242	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GHALPPDB_01232	8.99e-261	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
GHALPPDB_01233	9.46e-200	lysR5	-	-	K	-	-	-	LysR substrate binding domain
GHALPPDB_01234	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
GHALPPDB_01235	1.78e-107	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
GHALPPDB_01236	3.42e-73	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHALPPDB_01237	2.22e-116	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHALPPDB_01238	1.65e-77	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHALPPDB_01239	3.84e-189	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
GHALPPDB_01240	5.75e-40	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GHALPPDB_01241	1.32e-148	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
GHALPPDB_01242	8.09e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GHALPPDB_01243	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
GHALPPDB_01244	1.31e-149	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
GHALPPDB_01245	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GHALPPDB_01246	1.13e-30	-	-	-	-	-	-	-	-
GHALPPDB_01247	3.62e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GHALPPDB_01248	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
GHALPPDB_01249	2.79e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GHALPPDB_01250	1.19e-237	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GHALPPDB_01251	6.52e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
GHALPPDB_01252	6.73e-211	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GHALPPDB_01253	4.6e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GHALPPDB_01254	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GHALPPDB_01255	5.4e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
GHALPPDB_01256	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
GHALPPDB_01257	6.69e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
GHALPPDB_01258	8.01e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
GHALPPDB_01259	1.18e-168	-	-	-	-	-	-	-	-
GHALPPDB_01260	6.65e-216	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHALPPDB_01261	3.17e-60	-	-	-	-	-	-	-	-
GHALPPDB_01262	2.55e-61	-	-	-	-	-	-	-	-
GHALPPDB_01263	1.15e-21	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GHALPPDB_01264	3.17e-28	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
GHALPPDB_01265	1.1e-277	-	-	-	EGP	ko:K08196,ko:K08369	-	ko00000,ko02000	Major Facilitator
GHALPPDB_01266	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GHALPPDB_01267	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
GHALPPDB_01268	2.11e-271	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
GHALPPDB_01269	5.96e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
GHALPPDB_01271	4.02e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GHALPPDB_01272	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
GHALPPDB_01273	1.6e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
GHALPPDB_01274	1.36e-284	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
GHALPPDB_01275	6.89e-97	-	-	-	M	-	-	-	NlpC/P60 family
GHALPPDB_01276	7.78e-190	-	-	-	EG	-	-	-	EamA-like transporter family
GHALPPDB_01277	9.7e-140	-	-	-	-	-	-	-	-
GHALPPDB_01278	6.41e-101	-	-	-	-	-	-	-	-
GHALPPDB_01279	4.57e-75	-	-	-	S	-	-	-	DUF218 domain
GHALPPDB_01280	2.05e-130	-	-	-	S	-	-	-	DUF218 domain
GHALPPDB_01281	2.18e-168	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
GHALPPDB_01282	5.86e-39	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
GHALPPDB_01283	2.58e-108	-	-	-	-	-	-	-	-
GHALPPDB_01284	6.82e-74	-	-	-	-	-	-	-	-
GHALPPDB_01285	2.19e-307	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GHALPPDB_01286	1.38e-313	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GHALPPDB_01287	4.71e-233	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GHALPPDB_01290	1.75e-256	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
GHALPPDB_01291	3.5e-249	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
GHALPPDB_01292	6.47e-25	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
GHALPPDB_01293	2.98e-201	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
GHALPPDB_01294	9.45e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
GHALPPDB_01295	9.17e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
GHALPPDB_01296	1.34e-297	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GHALPPDB_01297	1.12e-87	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
GHALPPDB_01298	4.15e-60	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
GHALPPDB_01299	6.39e-26	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
GHALPPDB_01300	1.22e-53	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
GHALPPDB_01301	2.19e-56	-	-	-	S	-	-	-	Enterocin A Immunity
GHALPPDB_01302	1.12e-63	-	-	-	S	-	-	-	Fic/DOC family
GHALPPDB_01303	1.34e-34	-	-	-	S	-	-	-	Fic/DOC family
GHALPPDB_01304	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
GHALPPDB_01305	4.9e-283	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
GHALPPDB_01306	6.66e-68	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
GHALPPDB_01307	1.89e-127	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GHALPPDB_01308	2.34e-74	-	-	-	-	-	-	-	-
GHALPPDB_01309	0.0	-	-	-	S	-	-	-	ABC transporter
GHALPPDB_01310	1.14e-177	-	-	-	S	-	-	-	Putative threonine/serine exporter
GHALPPDB_01311	9.65e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
GHALPPDB_01312	3.04e-154	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
GHALPPDB_01313	1.79e-248	-	-	-	S	-	-	-	DUF218 domain
GHALPPDB_01314	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01315	1.33e-126	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
GHALPPDB_01316	2.08e-203	-	-	-	S	-	-	-	Aldo/keto reductase family
GHALPPDB_01317	7.74e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GHALPPDB_01318	3.09e-128	-	-	-	K	-	-	-	rpiR family
GHALPPDB_01319	6.62e-180	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
GHALPPDB_01320	5.12e-233	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase
GHALPPDB_01321	1.01e-161	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GHALPPDB_01322	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GHALPPDB_01323	4.4e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
GHALPPDB_01324	1.29e-208	-	-	-	M	-	-	-	Glycosyl transferase family 8
GHALPPDB_01325	5.08e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
GHALPPDB_01326	4.24e-184	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
GHALPPDB_01327	1.86e-165	-	-	-	I	-	-	-	Acyl-transferase
GHALPPDB_01328	3.27e-38	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
GHALPPDB_01329	1.34e-154	-	-	-	-	-	-	-	-
GHALPPDB_01331	9e-46	-	-	-	-	-	-	-	-
GHALPPDB_01333	2.3e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
GHALPPDB_01334	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GHALPPDB_01335	8.07e-314	yycH	-	-	S	-	-	-	YycH protein
GHALPPDB_01336	3.54e-190	yycI	-	-	S	-	-	-	YycH protein
GHALPPDB_01337	8.73e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
GHALPPDB_01338	1.18e-274	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
GHALPPDB_01339	2.23e-117	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GHALPPDB_01340	3.78e-64	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GHALPPDB_01341	4.41e-78	-	-	-	L	-	-	-	Helix-turn-helix domain
GHALPPDB_01342	7.24e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
GHALPPDB_01343	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01344	2.95e-139	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
GHALPPDB_01345	1.27e-142	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
GHALPPDB_01346	9.41e-32	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
GHALPPDB_01347	5.72e-12	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
GHALPPDB_01348	3.88e-140	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
GHALPPDB_01349	1.48e-127	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
GHALPPDB_01350	1.11e-87	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
GHALPPDB_01352	2.02e-80	-	-	-	S	-	-	-	Abi-like protein
GHALPPDB_01353	3.63e-80	kptA	-	-	H	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GHALPPDB_01354	4.58e-87	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
GHALPPDB_01355	7.55e-44	-	-	-	-	-	-	-	-
GHALPPDB_01356	1.22e-289	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
GHALPPDB_01357	1.12e-188	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
GHALPPDB_01358	8.01e-68	-	-	-	-	-	-	-	-
GHALPPDB_01359	1.44e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
GHALPPDB_01360	1.37e-152	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
GHALPPDB_01361	2.73e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
GHALPPDB_01362	1.31e-67	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
GHALPPDB_01365	2.17e-112	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GHALPPDB_01366	5.75e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GHALPPDB_01367	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
GHALPPDB_01368	5.17e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
GHALPPDB_01370	6.34e-136	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
GHALPPDB_01371	4.61e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
GHALPPDB_01372	1.14e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
GHALPPDB_01373	3.57e-136	-	-	-	L	-	-	-	Resolvase, N terminal domain
GHALPPDB_01374	0.0	-	-	-	L	-	-	-	Probable transposase
GHALPPDB_01375	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
GHALPPDB_01376	4.34e-100	-	-	-	KLT	-	-	-	serine threonine protein kinase
GHALPPDB_01377	1.51e-26	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
GHALPPDB_01378	1.24e-139	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
GHALPPDB_01379	2.23e-35	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
GHALPPDB_01380	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GHALPPDB_01381	9e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
GHALPPDB_01382	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GHALPPDB_01383	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
GHALPPDB_01384	3.86e-263	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
GHALPPDB_01385	1.72e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
GHALPPDB_01386	5e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
GHALPPDB_01387	6.77e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GHALPPDB_01388	3.91e-245	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
GHALPPDB_01389	9.86e-130	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
GHALPPDB_01390	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
GHALPPDB_01391	4.76e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
GHALPPDB_01392	4.42e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
GHALPPDB_01393	7.82e-69	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
GHALPPDB_01394	1.7e-314	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
GHALPPDB_01395	4.82e-55	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
GHALPPDB_01396	1.33e-99	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_01397	2.52e-166	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
GHALPPDB_01398	2.43e-56	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
GHALPPDB_01399	0.0	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
GHALPPDB_01400	5.91e-151	-	-	-	L	-	-	-	Resolvase, N terminal domain
GHALPPDB_01401	2.25e-51	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
GHALPPDB_01402	6.62e-285	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
GHALPPDB_01403	2.54e-38	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
GHALPPDB_01404	6.05e-121	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
GHALPPDB_01405	5.41e-123	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
GHALPPDB_01406	1.11e-51	-	-	-	-	-	-	-	-
GHALPPDB_01407	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
GHALPPDB_01408	4.69e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
GHALPPDB_01409	6.39e-73	-	-	-	K	-	-	-	Helix-turn-helix domain
GHALPPDB_01410	5.37e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GHALPPDB_01411	3.5e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
GHALPPDB_01412	1.42e-217	-	-	-	K	-	-	-	Transcriptional regulator
GHALPPDB_01413	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHALPPDB_01414	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GHALPPDB_01415	8.01e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GHALPPDB_01416	4.14e-214	snf	-	-	KL	-	-	-	domain protein
GHALPPDB_01417	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
GHALPPDB_01418	1.3e-121	-	-	-	K	-	-	-	acetyltransferase
GHALPPDB_01419	1.12e-42	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GHALPPDB_01420	9.16e-123	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GHALPPDB_01421	1.44e-188	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
GHALPPDB_01422	8.14e-73	-	-	-	-	-	-	-	-
GHALPPDB_01423	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
GHALPPDB_01424	8.82e-113	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
GHALPPDB_01425	3.89e-287	ptcC	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GHALPPDB_01426	4.31e-179	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
GHALPPDB_01427	2.22e-67	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
GHALPPDB_01428	4.77e-59	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
GHALPPDB_01429	3.87e-12	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
GHALPPDB_01430	7.82e-204	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
GHALPPDB_01431	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
GHALPPDB_01432	2.07e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
GHALPPDB_01433	5.59e-290	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
GHALPPDB_01434	0.0	yhaN	-	-	L	-	-	-	AAA domain
GHALPPDB_01435	1.16e-241	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
GHALPPDB_01436	1.19e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
GHALPPDB_01437	5.64e-200	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GHALPPDB_01438	3.49e-56	-	-	-	-	-	-	-	-
GHALPPDB_01439	3.94e-103	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
GHALPPDB_01440	6.86e-72	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
GHALPPDB_01441	9.02e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01442	5.32e-268	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
GHALPPDB_01443	7.82e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GHALPPDB_01444	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
GHALPPDB_01445	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHALPPDB_01446	0.0	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01447	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
GHALPPDB_01448	2.38e-225	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01449	2.61e-76	-	-	-	M	-	-	-	Peptidase family M1 domain
GHALPPDB_01450	2.69e-178	-	-	-	M	-	-	-	Peptidase family M1 domain
GHALPPDB_01451	1.05e-47	-	-	-	M	-	-	-	Peptidase family M1 domain
GHALPPDB_01452	1.53e-246	-	-	-	S	-	-	-	Bacteriocin helveticin-J
GHALPPDB_01453	3.05e-21	-	-	-	-	-	-	-	-
GHALPPDB_01454	1.87e-68	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
GHALPPDB_01455	9.65e-193	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
GHALPPDB_01456	3.72e-159	-	-	-	C	-	-	-	Flavodoxin
GHALPPDB_01457	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
GHALPPDB_01458	3.23e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GHALPPDB_01459	6.62e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GHALPPDB_01460	7.17e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
GHALPPDB_01461	1.55e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHALPPDB_01462	5.48e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHALPPDB_01463	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GHALPPDB_01464	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GHALPPDB_01465	8.29e-252	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
GHALPPDB_01466	1.78e-134	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GHALPPDB_01467	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
GHALPPDB_01468	1.31e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
GHALPPDB_01469	0.0	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
GHALPPDB_01470	1.11e-184	cas5	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
GHALPPDB_01471	0.0	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
GHALPPDB_01472	5.5e-203	csd2	-	-	L	ko:K19115,ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
GHALPPDB_01473	5.94e-161	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
GHALPPDB_01474	5.83e-251	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GHALPPDB_01475	2.86e-39	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GHALPPDB_01476	2.56e-19	-	-	-	-	-	-	-	-
GHALPPDB_01477	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GHALPPDB_01478	8.79e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GHALPPDB_01479	5.94e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GHALPPDB_01480	5.46e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GHALPPDB_01481	1.24e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
GHALPPDB_01482	1.79e-213	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
GHALPPDB_01483	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GHALPPDB_01484	3.9e-79	-	-	-	S	ko:K09707	-	ko00000	ACT domain
GHALPPDB_01485	4.33e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
GHALPPDB_01486	3.29e-52	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
GHALPPDB_01487	1.79e-242	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
GHALPPDB_01488	2.8e-72	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GHALPPDB_01489	4.77e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
GHALPPDB_01490	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GHALPPDB_01491	1.51e-121	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
GHALPPDB_01492	4.77e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
GHALPPDB_01493	2.14e-154	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GHALPPDB_01494	1.12e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
GHALPPDB_01495	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GHALPPDB_01496	2.57e-272	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
GHALPPDB_01497	8.27e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
GHALPPDB_01498	3.37e-161	csrR	-	-	K	-	-	-	response regulator
GHALPPDB_01499	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
GHALPPDB_01500	9.66e-110	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
GHALPPDB_01501	1.17e-202	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GHALPPDB_01502	9.28e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
GHALPPDB_01503	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GHALPPDB_01504	1.4e-80	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
GHALPPDB_01505	1.06e-256	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GHALPPDB_01506	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GHALPPDB_01507	2.74e-89	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GHALPPDB_01508	9.25e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
GHALPPDB_01509	1.18e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
GHALPPDB_01510	3.61e-224	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
GHALPPDB_01512	5.42e-42	-	-	-	-	-	-	-	-
GHALPPDB_01513	5.88e-47	-	-	-	-	-	-	-	-
GHALPPDB_01514	5.65e-75	-	-	-	L	-	-	-	NUDIX domain
GHALPPDB_01515	4.95e-216	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
GHALPPDB_01516	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
GHALPPDB_01517	5.02e-20	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GHALPPDB_01518	1.03e-140	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
GHALPPDB_01519	8.58e-139	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
GHALPPDB_01520	1.19e-118	-	-	-	K	-	-	-	Virulence activator alpha C-term
GHALPPDB_01521	7.45e-158	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
GHALPPDB_01522	1.75e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GHALPPDB_01523	1.86e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
GHALPPDB_01525	6.1e-64	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
GHALPPDB_01526	7.45e-120	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
GHALPPDB_01527	4.04e-112	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
GHALPPDB_01528	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
GHALPPDB_01529	0.0	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
GHALPPDB_01530	1.04e-20	-	-	-	V	-	-	-	Abi-like protein
GHALPPDB_01531	7.82e-10	-	-	-	V	-	-	-	Abi-like protein
GHALPPDB_01532	2.36e-22	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
GHALPPDB_01534	8.68e-41	-	-	-	V	-	-	-	Abi-like protein
GHALPPDB_01535	1.44e-21	-	-	-	V	-	-	-	Abi-like protein
GHALPPDB_01536	6.24e-18	-	-	-	K	-	-	-	LysR substrate binding domain
GHALPPDB_01537	6.28e-68	-	-	-	K	-	-	-	LysR substrate binding domain
GHALPPDB_01538	2.41e-263	-	-	-	C	-	-	-	FAD binding domain
GHALPPDB_01539	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
GHALPPDB_01540	1.36e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
GHALPPDB_01541	1.07e-245	ysdE	-	-	P	-	-	-	Citrate transporter
GHALPPDB_01542	2.37e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
GHALPPDB_01543	3.17e-205	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
GHALPPDB_01544	1e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
GHALPPDB_01545	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01546	7.55e-123	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
GHALPPDB_01547	6.55e-221	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GHALPPDB_01548	4.65e-100	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_01549	1.21e-124	-	-	-	S	-	-	-	Bacteriocin helveticin-J
GHALPPDB_01550	1.84e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
GHALPPDB_01553	7.07e-18	-	-	-	EP	-	-	-	Plasmid replication protein
GHALPPDB_01554	1.33e-55	-	-	-	O	-	-	-	RNA helicase
GHALPPDB_01556	4.38e-196	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GHALPPDB_01557	3.52e-311	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GHALPPDB_01559	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
GHALPPDB_01560	3.84e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01561	1.66e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
GHALPPDB_01562	7.86e-50	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GHALPPDB_01563	3.39e-58	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
GHALPPDB_01564	3.74e-175	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GHALPPDB_01565	0.0	-	-	-	V	-	-	-	Restriction endonuclease
GHALPPDB_01566	2.46e-184	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GHALPPDB_01567	3.59e-264	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
GHALPPDB_01568	1.14e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
GHALPPDB_01569	6.08e-312	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
GHALPPDB_01570	2.32e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
GHALPPDB_01571	6.59e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GHALPPDB_01572	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GHALPPDB_01573	8.41e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GHALPPDB_01574	5.54e-51	-	-	-	-	-	-	-	-
GHALPPDB_01575	2.39e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GHALPPDB_01576	1.35e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GHALPPDB_01577	3.46e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
GHALPPDB_01578	4.64e-53	-	-	-	S	-	-	-	Enterocin A Immunity
GHALPPDB_01579	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHALPPDB_01580	1.39e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
GHALPPDB_01581	2.11e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GHALPPDB_01582	2.06e-104	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
GHALPPDB_01583	1e-92	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
GHALPPDB_01584	3.72e-201	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_01585	5.55e-69	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_01586	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GHALPPDB_01587	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GHALPPDB_01588	6.1e-213	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
GHALPPDB_01589	6.12e-193	-	-	-	S	-	-	-	reductase
GHALPPDB_01590	2.01e-178	yxeH	-	-	S	-	-	-	hydrolase
GHALPPDB_01591	2.84e-21	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHALPPDB_01592	6.35e-173	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GHALPPDB_01593	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
GHALPPDB_01594	2.12e-80	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
GHALPPDB_01595	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GHALPPDB_01596	1.55e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GHALPPDB_01597	0.0	oatA	-	-	I	-	-	-	Acyltransferase
GHALPPDB_01598	3.02e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GHALPPDB_01599	2.31e-132	-	-	-	L	-	-	-	Integrase
GHALPPDB_01600	1.03e-61	-	-	-	-	-	-	-	-
GHALPPDB_01601	1.46e-110	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
GHALPPDB_01602	1.48e-72	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
GHALPPDB_01603	8.74e-142	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
GHALPPDB_01604	3.64e-24	-	-	-	-	-	-	-	-
GHALPPDB_01605	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
GHALPPDB_01606	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
GHALPPDB_01607	1.39e-36	-	-	-	-	-	-	-	-
GHALPPDB_01608	3.47e-54	-	-	-	-	-	-	-	-
GHALPPDB_01609	7.53e-110	-	-	-	-	-	-	-	-
GHALPPDB_01610	4.88e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
GHALPPDB_01611	7.76e-218	repA	-	-	S	-	-	-	Replication initiator protein A
GHALPPDB_01612	9.39e-184	-	-	-	D	-	-	-	AAA domain
GHALPPDB_01613	4.07e-39	-	-	-	-	-	-	-	-
GHALPPDB_01615	4.56e-33	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
GHALPPDB_01616	1.48e-49	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
GHALPPDB_01617	1.87e-158	terC	-	-	P	-	-	-	Integral membrane protein TerC family
GHALPPDB_01618	2.78e-82	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
GHALPPDB_01619	5.11e-158	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
GHALPPDB_01620	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_01621	2.38e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_01622	3.72e-201	-	-	-	L	-	-	-	HNH nucleases
GHALPPDB_01623	2.94e-155	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
GHALPPDB_01624	5.08e-190	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
GHALPPDB_01625	2.09e-286	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
GHALPPDB_01626	3.56e-180	-	-	-	-	-	-	-	-
GHALPPDB_01627	9.69e-25	-	-	-	-	-	-	-	-
GHALPPDB_01628	3.69e-50	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
GHALPPDB_01629	1.1e-206	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
GHALPPDB_01630	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GHALPPDB_01631	3.11e-141	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GHALPPDB_01632	2.5e-59	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GHALPPDB_01633	1.81e-29	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
GHALPPDB_01634	1.25e-241	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
GHALPPDB_01635	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
GHALPPDB_01636	4.53e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
GHALPPDB_01637	6.23e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
GHALPPDB_01638	2.07e-56	-	-	-	O	-	-	-	Matrixin
GHALPPDB_01640	5.43e-296	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GHALPPDB_01641	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
GHALPPDB_01642	2.95e-236	eriC	-	-	P	ko:K03281	-	ko00000	chloride
GHALPPDB_01643	2.51e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GHALPPDB_01644	2.78e-158	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GHALPPDB_01645	5.1e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GHALPPDB_01646	1.38e-120	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GHALPPDB_01647	1.56e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
GHALPPDB_01648	1.93e-302	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GHALPPDB_01649	1.3e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GHALPPDB_01650	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GHALPPDB_01651	3.46e-07	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
GHALPPDB_01652	8.27e-09	-	-	-	-	-	-	-	-
GHALPPDB_01653	1.29e-53	-	-	-	-	-	-	-	-
GHALPPDB_01655	1.78e-175	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
GHALPPDB_01656	1.06e-62	-	-	-	-	-	-	-	-
GHALPPDB_01657	2.21e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
GHALPPDB_01658	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GHALPPDB_01659	1.54e-74	-	-	-	S	-	-	-	Bacterial PH domain
GHALPPDB_01660	7.87e-37	-	-	-	-	-	-	-	-
GHALPPDB_01661	1.55e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
GHALPPDB_01662	7.13e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
GHALPPDB_01664	1.83e-264	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GHALPPDB_01665	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
GHALPPDB_01666	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
GHALPPDB_01667	1.01e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
GHALPPDB_01668	6.01e-306	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
GHALPPDB_01669	1.49e-252	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
GHALPPDB_01670	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
GHALPPDB_01671	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
GHALPPDB_01672	5.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
GHALPPDB_01673	1.64e-261	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
GHALPPDB_01674	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GHALPPDB_01675	9.01e-89	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
GHALPPDB_01676	5.2e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GHALPPDB_01677	5.03e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GHALPPDB_01678	5.59e-251	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHALPPDB_01679	6.25e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GHALPPDB_01680	2.06e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
GHALPPDB_01681	4.01e-194	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
GHALPPDB_01682	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
GHALPPDB_01683	2.46e-102	-	-	-	S	-	-	-	ASCH
GHALPPDB_01684	1.64e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
GHALPPDB_01685	5.6e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GHALPPDB_01686	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GHALPPDB_01687	1.6e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GHALPPDB_01688	2.87e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GHALPPDB_01689	9.08e-187	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
GHALPPDB_01690	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
GHALPPDB_01691	9.22e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GHALPPDB_01692	1.63e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
GHALPPDB_01693	1.06e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
GHALPPDB_01694	1.98e-64	-	-	-	-	-	-	-	-
GHALPPDB_01695	3.82e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
GHALPPDB_01696	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
GHALPPDB_01697	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
GHALPPDB_01698	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GHALPPDB_01699	4.31e-232	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GHALPPDB_01700	8.89e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GHALPPDB_01701	2.11e-249	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GHALPPDB_01702	3.41e-231	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
GHALPPDB_01703	7.39e-226	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
GHALPPDB_01704	1.56e-190	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GHALPPDB_01705	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GHALPPDB_01706	1.73e-218	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
GHALPPDB_01707	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
GHALPPDB_01708	2.29e-273	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
GHALPPDB_01710	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
GHALPPDB_01711	5.58e-91	-	-	-	S	-	-	-	Phage Mu protein F like protein
GHALPPDB_01712	6.56e-43	-	-	-	S	-	-	-	Phage Mu protein F like protein
GHALPPDB_01713	2.63e-130	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
GHALPPDB_01715	6.04e-203	-	-	-	V	-	-	-	ABC transporter transmembrane region
GHALPPDB_01716	1.17e-78	-	-	-	S	-	-	-	GIY-YIG catalytic domain
GHALPPDB_01718	1.48e-194	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type cobalt transport system permease component CbiQ and related transporters
GHALPPDB_01719	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
GHALPPDB_01720	1.23e-162	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
GHALPPDB_01721	1.54e-62	-	-	-	U	-	-	-	FFAT motif binding
GHALPPDB_01722	9.76e-104	-	-	-	U	-	-	-	FFAT motif binding
GHALPPDB_01723	4.2e-24	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
GHALPPDB_01724	1.33e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
GHALPPDB_01725	2.49e-234	-	-	-	U	-	-	-	FFAT motif binding
GHALPPDB_01726	0.0	-	-	-	S	ko:K21449	-	ko00000,ko02000	Domain of unknown function (DUF4430)
GHALPPDB_01727	2.2e-68	-	-	-	-	-	-	-	-
GHALPPDB_01728	1.62e-63	-	-	-	-	-	-	-	-
GHALPPDB_01729	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
GHALPPDB_01730	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
GHALPPDB_01731	4.19e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
GHALPPDB_01732	2.65e-246	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
GHALPPDB_01733	2.27e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
GHALPPDB_01734	5.13e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
GHALPPDB_01735	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
GHALPPDB_01736	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
GHALPPDB_01737	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
GHALPPDB_01738	8.34e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
GHALPPDB_01739	2.52e-209	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
GHALPPDB_01740	4.5e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GHALPPDB_01741	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
GHALPPDB_01742	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
GHALPPDB_01743	1.56e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GHALPPDB_01744	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
GHALPPDB_01745	3.13e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GHALPPDB_01746	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GHALPPDB_01747	1.63e-65	-	-	-	-	-	-	-	-
GHALPPDB_01748	1.24e-168	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
GHALPPDB_01749	2.83e-115	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
GHALPPDB_01751	3.89e-151	-	-	-	L	-	-	-	Integrase
GHALPPDB_01753	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
GHALPPDB_01754	1.25e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
GHALPPDB_01755	3.5e-77	-	-	-	S	-	-	-	Alpha beta hydrolase
GHALPPDB_01756	1.71e-26	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
GHALPPDB_01757	3.33e-49	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
GHALPPDB_01758	5.69e-185	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
GHALPPDB_01759	5.21e-41	-	1.1.1.3	-	T	ko:K00003,ko:K07166	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoserine phosphatase activity
GHALPPDB_01760	2.02e-09	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
GHALPPDB_01761	2.44e-134	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GHALPPDB_01769	1.14e-277	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
GHALPPDB_01770	1.28e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
GHALPPDB_01771	2.25e-222	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GHALPPDB_01772	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
GHALPPDB_01773	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
GHALPPDB_01774	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GHALPPDB_01775	1.3e-100	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GHALPPDB_01776	3.04e-119	-	-	-	L	-	-	-	transposase activity
GHALPPDB_01777	1.06e-37	-	-	-	S	-	-	-	Enterocin A Immunity
GHALPPDB_01778	1.73e-30	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GHALPPDB_01779	7.56e-157	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
GHALPPDB_01780	3.01e-153	-	-	-	S	-	-	-	PAS domain
GHALPPDB_01781	2.37e-175	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
GHALPPDB_01782	1.34e-261	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
GHALPPDB_01783	1.97e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
GHALPPDB_01784	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GHALPPDB_01785	2.58e-163	-	-	-	F	-	-	-	NUDIX domain
GHALPPDB_01786	1.37e-94	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
GHALPPDB_01787	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
GHALPPDB_01788	4.32e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GHALPPDB_01789	2.15e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
GHALPPDB_01790	4.89e-159	-	-	-	S	-	-	-	membrane
GHALPPDB_01791	1.39e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
GHALPPDB_01792	1.33e-289	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
GHALPPDB_01793	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GHALPPDB_01794	5.17e-30	-	-	-	-	-	-	-	-
GHALPPDB_01795	1.33e-30	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
GHALPPDB_01796	2.41e-27	-	-	-	-	-	-	-	-
GHALPPDB_01799	1.7e-106	-	-	-	V	-	-	-	COG4823 Abortive infection bacteriophage resistance protein
GHALPPDB_01800	1.34e-152	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GHALPPDB_01801	4.99e-123	-	-	-	L	-	-	-	reverse transcriptase
GHALPPDB_01803	7.9e-28	-	-	-	-	-	-	-	-
GHALPPDB_01804	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GHALPPDB_01805	3.96e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
GHALPPDB_01806	4.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
GHALPPDB_01807	2.33e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GHALPPDB_01808	9.35e-161	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
GHALPPDB_01809	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
GHALPPDB_01810	1.2e-207	-	-	-	-	-	-	-	-
GHALPPDB_01811	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
GHALPPDB_01812	3.9e-125	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GHALPPDB_01813	4.96e-202	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
GHALPPDB_01814	1.36e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
GHALPPDB_01815	7.08e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
GHALPPDB_01816	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
GHALPPDB_01817	6.84e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GHALPPDB_01818	1.15e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
GHALPPDB_01819	4.47e-255	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
GHALPPDB_01820	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
GHALPPDB_01821	5.95e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
GHALPPDB_01822	8.85e-217	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
GHALPPDB_01823	7.26e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GHALPPDB_01824	5.62e-138	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
GHALPPDB_01825	1.82e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
GHALPPDB_01826	1.91e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
GHALPPDB_01827	3.9e-181	-	-	-	-	-	-	-	-
GHALPPDB_01828	5.09e-160	-	-	-	S	-	-	-	PAS domain
GHALPPDB_01829	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
GHALPPDB_01830	2.91e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
GHALPPDB_01831	2.83e-237	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GHALPPDB_01832	2.65e-123	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
GHALPPDB_01834	6.39e-69	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
GHALPPDB_01835	1.9e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
GHALPPDB_01836	5.59e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GHALPPDB_01837	5.55e-219	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
GHALPPDB_01838	3.38e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
GHALPPDB_01839	4.94e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
GHALPPDB_01840	1.06e-192	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
GHALPPDB_01841	1.57e-141	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
GHALPPDB_01842	8.97e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GHALPPDB_01843	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
GHALPPDB_01844	5.02e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
GHALPPDB_01845	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
GHALPPDB_01846	5.48e-23	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
GHALPPDB_01847	2.44e-304	-	-	-	S	-	-	-	response to antibiotic
GHALPPDB_01848	1.76e-160	-	-	-	-	-	-	-	-
GHALPPDB_01849	1.46e-21	-	-	-	-	-	-	-	-
GHALPPDB_01850	1.52e-237	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
GHALPPDB_01851	6.25e-171	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
GHALPPDB_01852	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
GHALPPDB_01853	3.49e-48	-	-	-	-	-	-	-	-
GHALPPDB_01854	1.91e-124	-	-	-	-	-	-	-	-
GHALPPDB_01855	4.62e-136	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
GHALPPDB_01856	4.43e-143	-	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_01857	4.15e-131	-	-	-	S	-	-	-	AAA ATPase domain
GHALPPDB_01858	1.02e-232	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GHALPPDB_01859	9.2e-148	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GHALPPDB_01860	3.6e-209	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GHALPPDB_01861	6.96e-269	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GHALPPDB_01862	5.22e-276	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
GHALPPDB_01866	6.52e-34	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
GHALPPDB_01867	3.71e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
GHALPPDB_01869	8.76e-80	-	-	-	L	-	-	-	RelB antitoxin
GHALPPDB_01871	4.68e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
GHALPPDB_01872	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GHALPPDB_01873	4.7e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GHALPPDB_01874	1.23e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
GHALPPDB_01875	2.32e-142	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GHALPPDB_01876	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
GHALPPDB_01878	1.43e-84	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
GHALPPDB_01879	4.61e-118	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
GHALPPDB_01880	7.22e-133	-	-	-	L	-	-	-	HTH-like domain
GHALPPDB_01881	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
GHALPPDB_01882	3.58e-216	degS	2.7.13.3	-	F	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
GHALPPDB_01883	1.52e-43	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
GHALPPDB_01884	1.6e-41	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
GHALPPDB_01885	2.43e-234	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
GHALPPDB_01886	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GHALPPDB_01887	9.06e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GHALPPDB_01888	5.74e-142	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
GHALPPDB_01889	3.03e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
GHALPPDB_01890	1.13e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GHALPPDB_01891	1.09e-256	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
GHALPPDB_01892	1.09e-169	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
GHALPPDB_01893	3.66e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
GHALPPDB_01894	4.11e-52	-	-	-	S	-	-	-	ThiS family
GHALPPDB_01895	2.36e-164	moeB	2.7.7.80, 2.8.1.11	-	H	ko:K21029,ko:K21147	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
GHALPPDB_01896	4.8e-212	-	-	-	EGP	-	-	-	Major facilitator Superfamily
GHALPPDB_01899	2.45e-205	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GHALPPDB_01900	8.96e-122	-	-	-	-	-	-	-	-
GHALPPDB_01901	1.18e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
GHALPPDB_01902	5.22e-136	-	-	-	-	-	-	-	-
GHALPPDB_01903	5.05e-47	-	-	-	-	-	-	-	-
GHALPPDB_01904	6.56e-114	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
GHALPPDB_01905	1.26e-24	-	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_01906	2.3e-57	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GHALPPDB_01907	5.18e-109	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
GHALPPDB_01908	4.34e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
GHALPPDB_01909	7e-114	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
GHALPPDB_01910	3.85e-34	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
GHALPPDB_01911	1.64e-237	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
GHALPPDB_01912	8.74e-195	-	-	-	C	-	-	-	Nitroreductase
GHALPPDB_01915	4.65e-168	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
GHALPPDB_01916	8.78e-155	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
GHALPPDB_01917	5.26e-38	-	-	-	-	-	-	-	-
GHALPPDB_01918	2.15e-48	-	-	-	S	-	-	-	Transglycosylase associated protein
GHALPPDB_01919	1.13e-71	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GHALPPDB_01920	8.5e-35	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
GHALPPDB_01921	1.92e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
GHALPPDB_01922	2.73e-32	flaR	-	-	F	-	-	-	topology modulation protein
GHALPPDB_01923	3.71e-95	-	-	-	-	-	-	-	-
GHALPPDB_01924	4.67e-105	-	-	-	M	-	-	-	domain protein
GHALPPDB_01926	7.82e-211	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
GHALPPDB_01927	7.17e-43	-	-	-	M	-	-	-	Rib/alpha-like repeat
GHALPPDB_01928	1.26e-158	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
GHALPPDB_01929	7.74e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
GHALPPDB_01930	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
GHALPPDB_01931	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GHALPPDB_01932	2.72e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
GHALPPDB_01933	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
GHALPPDB_01934	6.65e-234	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GHALPPDB_01935	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
GHALPPDB_01936	2.98e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
GHALPPDB_01937	1.48e-216	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
GHALPPDB_01938	5.23e-77	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GHALPPDB_01939	3e-168	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GHALPPDB_01940	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GHALPPDB_01941	3.14e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
GHALPPDB_01942	2.09e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GHALPPDB_01943	1.09e-66	-	-	-	M	-	-	-	Lysin motif
GHALPPDB_01944	1.81e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
GHALPPDB_01945	8.97e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
GHALPPDB_01946	1.5e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
GHALPPDB_01947	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GHALPPDB_01948	1.87e-290	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
GHALPPDB_01949	7.21e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GHALPPDB_01950	1.26e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GHALPPDB_01951	5.77e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
GHALPPDB_01952	1.37e-189	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
GHALPPDB_01953	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
GHALPPDB_01954	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
GHALPPDB_01955	1.11e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GHALPPDB_01956	1.09e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHALPPDB_01957	3.85e-198	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
GHALPPDB_01958	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GHALPPDB_01959	1.14e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GHALPPDB_01960	3.76e-215	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
GHALPPDB_01961	1.15e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GHALPPDB_01962	1.49e-309	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GHALPPDB_01963	2.12e-224	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
GHALPPDB_01964	5e-32	-	-	-	-	-	-	-	-
GHALPPDB_01965	1.35e-39	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
GHALPPDB_01966	1.41e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives
GHALPPDB_01967	6.6e-28	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
GHALPPDB_01968	3.16e-36	-	-	-	L	-	-	-	Transposase and inactivated derivatives
GHALPPDB_01969	2.43e-75	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GHALPPDB_01970	1.06e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
GHALPPDB_01971	4.86e-84	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHALPPDB_01972	2.08e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GHALPPDB_01973	4.62e-37	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
GHALPPDB_01974	1.42e-60	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
GHALPPDB_01975	0.0	-	-	-	E	-	-	-	Amino acid permease
GHALPPDB_01976	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
GHALPPDB_01977	6.31e-314	ynbB	-	-	P	-	-	-	aluminum resistance
GHALPPDB_01978	8.62e-75	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
GHALPPDB_01979	1.43e-47	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
GHALPPDB_01980	1.59e-86	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
GHALPPDB_01981	2.89e-75	-	-	-	-	-	-	-	-
GHALPPDB_01982	3.29e-87	-	-	-	-	-	-	-	-
GHALPPDB_01983	6.21e-53	-	-	-	S	-	-	-	Fic/DOC family
GHALPPDB_01984	7.34e-72	-	-	-	S	-	-	-	Fic/DOC family
GHALPPDB_01985	4.75e-132	-	-	-	-	-	-	-	-
GHALPPDB_01986	4.04e-265	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
GHALPPDB_01987	5.26e-173	-	-	-	-	-	-	-	-
GHALPPDB_01988	9.73e-69	-	-	-	-	-	-	-	-
GHALPPDB_01989	5.83e-08	-	-	-	-	-	-	-	-
GHALPPDB_01991	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
GHALPPDB_01992	5.26e-63	-	-	-	K	-	-	-	Helix-turn-helix
GHALPPDB_01993	1.4e-108	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
GHALPPDB_01995	1.06e-136	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
GHALPPDB_01996	6.8e-39	-	-	-	-	-	-	-	-
GHALPPDB_01997	4.75e-167	-	-	-	-	-	-	-	-
GHALPPDB_01998	3.86e-108	-	-	-	-	-	-	-	-
GHALPPDB_01999	6.15e-68	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
GHALPPDB_02000	1.51e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
GHALPPDB_02001	3.74e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
GHALPPDB_02003	4.45e-83	-	-	-	-	-	-	-	-
GHALPPDB_02004	2.93e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
GHALPPDB_02005	1.9e-15	-	-	-	S	-	-	-	CsbD-like
GHALPPDB_02006	5.32e-35	-	-	-	S	-	-	-	Transglycosylase associated protein
GHALPPDB_02007	5.5e-303	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
GHALPPDB_02008	1.26e-154	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
GHALPPDB_02010	1.22e-37	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GHALPPDB_02011	2.93e-199	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GHALPPDB_02012	3.29e-132	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
GHALPPDB_02013	6.43e-82	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GHALPPDB_02014	1.77e-09	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
GHALPPDB_02015	2.28e-149	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
GHALPPDB_02016	6.32e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
GHALPPDB_02017	1.9e-11	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
GHALPPDB_02018	2.15e-35	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
GHALPPDB_02019	2.32e-85	-	-	-	-	-	-	-	-
GHALPPDB_02020	1.52e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
GHALPPDB_02021	5.71e-262	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
GHALPPDB_02022	1.76e-109	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
GHALPPDB_02023	6.88e-34	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
GHALPPDB_02025	1.16e-21	-	-	-	C	-	-	-	nitroreductase
GHALPPDB_02028	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
GHALPPDB_02029	1.6e-169	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
GHALPPDB_02030	0.0	-	-	-	-	-	-	-	-
GHALPPDB_02031	0.0	-	-	-	S	-	-	-	PglZ domain
GHALPPDB_02033	2.36e-68	-	-	-	LO	-	-	-	Belongs to the peptidase S16 family
GHALPPDB_02034	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
GHALPPDB_02035	4.02e-255	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
GHALPPDB_02036	8.2e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
GHALPPDB_02037	7.8e-135	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
GHALPPDB_02038	3.41e-294	-	-	-	S	-	-	-	Protein of unknown function DUF262
GHALPPDB_02039	1.56e-39	-	-	-	-	-	-	-	-
GHALPPDB_02040	1.55e-16	-	-	-	-	-	-	-	-
GHALPPDB_02041	1.72e-69	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
GHALPPDB_02042	1.39e-141	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
GHALPPDB_02043	5.57e-117	dpsB	-	-	P	-	-	-	Belongs to the Dps family
GHALPPDB_02044	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
GHALPPDB_02045	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
GHALPPDB_02046	7.15e-55	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
GHALPPDB_02047	2.43e-30	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
GHALPPDB_02048	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
GHALPPDB_02049	2.4e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
GHALPPDB_02050	5.36e-219	yobV3	-	-	K	-	-	-	WYL domain
GHALPPDB_02051	2.33e-103	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
GHALPPDB_02052	2.1e-44	-	-	-	-	-	-	-	-
GHALPPDB_02053	1.36e-71	-	-	-	-	-	-	-	-
GHALPPDB_02054	4.22e-71	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
GHALPPDB_02055	9.99e-86	-	-	-	S	-	-	-	ASCH domain
GHALPPDB_02056	1.05e-142	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GHALPPDB_02057	5.82e-105	-	-	-	-	-	-	-	-
GHALPPDB_02058	0.0	-	-	-	-	-	-	-	-
GHALPPDB_02059	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
GHALPPDB_02060	1.01e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
GHALPPDB_02061	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
GHALPPDB_02062	2.03e-100	-	-	-	-	-	-	-	-
GHALPPDB_02063	3.39e-116	-	-	-	-	-	-	-	-
GHALPPDB_02065	5.3e-184	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
GHALPPDB_02067	3.83e-277	-	-	-	S	-	-	-	SLAP domain
GHALPPDB_02068	1.43e-45	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
GHALPPDB_02069	2.37e-20	-	-	-	-	-	-	-	-
GHALPPDB_02070	1.6e-170	-	-	-	-	-	-	-	-
GHALPPDB_02071	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GHALPPDB_02072	2.01e-141	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GHALPPDB_02073	6.31e-65	-	-	-	V	-	-	-	Beta-lactamase
GHALPPDB_02074	9.54e-208	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
GHALPPDB_02075	1.83e-40	yebC	-	-	M	-	-	-	Membrane
GHALPPDB_02077	4.09e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
GHALPPDB_02078	1.52e-43	-	-	-	-	-	-	-	-
GHALPPDB_02079	7.69e-87	-	-	-	-	-	-	-	-
GHALPPDB_02080	3.85e-200	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
GHALPPDB_02081	2.76e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
GHALPPDB_02082	3.06e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
GHALPPDB_02083	1.27e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
GHALPPDB_02084	1.42e-57	-	-	-	-	-	-	-	-
GHALPPDB_02085	3.08e-37	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_02086	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
GHALPPDB_02087	4.04e-137	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
GHALPPDB_02088	7.59e-178	yxeH	-	-	S	-	-	-	hydrolase
GHALPPDB_02089	1.66e-15	-	-	-	S	-	-	-	Enterocin A Immunity
GHALPPDB_02090	1.09e-141	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
GHALPPDB_02091	7.53e-128	-	-	-	K	-	-	-	LysR substrate binding domain
GHALPPDB_02092	1.44e-52	-	-	-	K	-	-	-	LysR substrate binding domain
GHALPPDB_02094	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
GHALPPDB_02095	4.74e-286	yttB	-	-	EGP	-	-	-	Major Facilitator
GHALPPDB_02096	8.61e-294	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
GHALPPDB_02097	5.57e-129	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
GHALPPDB_02098	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GHALPPDB_02099	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
GHALPPDB_02101	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
GHALPPDB_02102	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
GHALPPDB_02103	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
GHALPPDB_02104	4.98e-107	-	-	-	-	-	-	-	-
GHALPPDB_02105	7.09e-77	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
GHALPPDB_02106	4.13e-187	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GHALPPDB_02107	2.04e-164	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
GHALPPDB_02108	2.82e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GHALPPDB_02109	4.39e-198	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
GHALPPDB_02111	3.78e-112	usp5	-	-	T	-	-	-	universal stress protein
GHALPPDB_02112	8.38e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
GHALPPDB_02113	1.26e-111	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GHALPPDB_02114	8.67e-111	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
GHALPPDB_02115	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
GHALPPDB_02116	3.08e-43	-	-	-	-	-	-	-	-
GHALPPDB_02117	5.96e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
GHALPPDB_02118	1.35e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
GHALPPDB_02119	3.81e-255	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
GHALPPDB_02120	6.11e-152	-	-	-	-	-	-	-	-
GHALPPDB_02121	1.46e-264	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
GHALPPDB_02122	2.12e-292	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
GHALPPDB_02123	5.22e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
GHALPPDB_02124	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
GHALPPDB_02125	3.27e-170	-	-	-	-	-	-	-	-
GHALPPDB_02126	2.58e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
GHALPPDB_02127	6.88e-231	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GHALPPDB_02128	1.49e-71	-	-	-	-	-	-	-	-
GHALPPDB_02129	3.43e-148	-	-	-	GM	-	-	-	NmrA-like family
GHALPPDB_02130	2.62e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
GHALPPDB_02131	1.07e-203	epsV	-	-	S	-	-	-	glycosyl transferase family 2
GHALPPDB_02132	1.56e-181	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
GHALPPDB_02133	2.82e-185	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GHALPPDB_02134	1.09e-226	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
GHALPPDB_02135	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GHALPPDB_02136	1.14e-111	-	-	-	-	-	-	-	-
GHALPPDB_02137	6.97e-85	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family