Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HFBFALPA_00001	2.08e-11	-	-	-	-	-	-	-	-
HFBFALPA_00002	3.55e-149	-	-	-	-	-	-	-	-
HFBFALPA_00003	2.91e-99	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
HFBFALPA_00004	9.81e-225	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HFBFALPA_00005	2.93e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HFBFALPA_00006	4.45e-83	-	-	-	-	-	-	-	-
HFBFALPA_00008	3.74e-154	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HFBFALPA_00009	1.51e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
HFBFALPA_00010	6.15e-68	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
HFBFALPA_00012	1.26e-154	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HFBFALPA_00013	5.5e-303	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HFBFALPA_00014	5.32e-35	-	-	-	S	-	-	-	Transglycosylase associated protein
HFBFALPA_00015	1.9e-15	-	-	-	S	-	-	-	CsbD-like
HFBFALPA_00016	1.77e-09	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFBFALPA_00017	6.43e-82	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFBFALPA_00018	3.29e-132	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFBFALPA_00019	2.93e-199	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFBFALPA_00020	1.22e-37	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFBFALPA_00021	2.15e-35	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFBFALPA_00022	1.9e-11	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
HFBFALPA_00023	6.32e-264	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HFBFALPA_00024	2.28e-149	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
HFBFALPA_00025	1.38e-20	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HFBFALPA_00026	5.6e-19	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HFBFALPA_00027	6.47e-144	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_00028	2.32e-85	-	-	-	-	-	-	-	-
HFBFALPA_00029	1.52e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HFBFALPA_00030	5.71e-262	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HFBFALPA_00031	7.82e-69	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HFBFALPA_00032	1.7e-314	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HFBFALPA_00033	4.82e-55	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HFBFALPA_00034	3.39e-116	-	-	-	-	-	-	-	-
HFBFALPA_00035	2.03e-100	-	-	-	-	-	-	-	-
HFBFALPA_00037	5.3e-184	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HFBFALPA_00039	3.83e-277	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_00040	4.48e-60	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_00041	2.46e-289	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFBFALPA_00042	4.82e-46	-	-	-	-	-	-	-	-
HFBFALPA_00043	8.25e-101	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
HFBFALPA_00044	4.19e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HFBFALPA_00045	2.57e-64	-	-	-	S	-	-	-	Cupredoxin-like domain
HFBFALPA_00046	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFBFALPA_00047	7.33e-151	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HFBFALPA_00048	1.14e-90	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HFBFALPA_00049	6.46e-27	-	-	-	-	-	-	-	-
HFBFALPA_00050	1.25e-264	-	-	-	-	-	-	-	-
HFBFALPA_00051	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFBFALPA_00052	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFBFALPA_00053	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFBFALPA_00054	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFBFALPA_00055	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFBFALPA_00056	4.38e-188	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFBFALPA_00057	1.31e-81	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFBFALPA_00058	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HFBFALPA_00059	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFBFALPA_00060	5.01e-255	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFBFALPA_00061	4.08e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HFBFALPA_00062	2.09e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFBFALPA_00063	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFBFALPA_00064	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFBFALPA_00065	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HFBFALPA_00066	4.15e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFBFALPA_00067	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFBFALPA_00068	3.08e-41	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_00069	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HFBFALPA_00070	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFBFALPA_00071	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HFBFALPA_00072	8.1e-209	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
HFBFALPA_00073	1.61e-224	degV1	-	-	S	-	-	-	DegV family
HFBFALPA_00074	2.99e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HFBFALPA_00075	8.03e-41	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFBFALPA_00076	6.17e-95	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFBFALPA_00077	1.6e-170	-	-	-	-	-	-	-	-
HFBFALPA_00078	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFBFALPA_00079	2.01e-141	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFBFALPA_00080	2.19e-124	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HFBFALPA_00081	7.67e-234	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HFBFALPA_00083	1.83e-40	yebC	-	-	M	-	-	-	Membrane
HFBFALPA_00084	9.54e-208	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFBFALPA_00085	6.31e-65	-	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_00086	1.42e-57	-	-	-	-	-	-	-	-
HFBFALPA_00087	1.27e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFBFALPA_00088	3.06e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HFBFALPA_00089	2.76e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFBFALPA_00090	4.09e-92	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFBFALPA_00091	1.52e-43	-	-	-	-	-	-	-	-
HFBFALPA_00092	7.69e-87	-	-	-	-	-	-	-	-
HFBFALPA_00093	3.85e-200	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HFBFALPA_00094	0.0	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative DNA-binding domain
HFBFALPA_00095	3.08e-37	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_00096	9.74e-52	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFBFALPA_00097	1.66e-15	-	-	-	S	-	-	-	Enterocin A Immunity
HFBFALPA_00098	7.59e-178	yxeH	-	-	S	-	-	-	hydrolase
HFBFALPA_00099	4.04e-137	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_00104	1.44e-52	-	-	-	K	-	-	-	LysR substrate binding domain
HFBFALPA_00105	7.53e-128	-	-	-	K	-	-	-	LysR substrate binding domain
HFBFALPA_00106	1.09e-141	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HFBFALPA_00107	1.95e-07	-	-	-	E	-	-	-	Preprotein translocase subunit SecB
HFBFALPA_00110	2.98e-83	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HFBFALPA_00111	1.77e-61	-	-	-	-	-	-	-	-
HFBFALPA_00112	7.2e-197	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFBFALPA_00113	7e-103	-	-	-	S	-	-	-	Putative adhesin
HFBFALPA_00114	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
HFBFALPA_00115	1.37e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HFBFALPA_00116	9e-66	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HFBFALPA_00117	1.06e-258	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HFBFALPA_00118	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HFBFALPA_00119	1.69e-107	ykuL	-	-	S	-	-	-	(CBS) domain
HFBFALPA_00120	3.66e-274	-	-	-	S	-	-	-	Membrane
HFBFALPA_00121	2.34e-66	-	-	-	-	-	-	-	-
HFBFALPA_00122	3.2e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HFBFALPA_00123	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBFALPA_00124	2.08e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HFBFALPA_00125	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFBFALPA_00126	1.05e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFBFALPA_00127	2.66e-221	pbpX2	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_00129	1.87e-11	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFBFALPA_00130	1.37e-56	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFBFALPA_00131	7.99e-37	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFBFALPA_00132	8.02e-38	-	-	-	-	-	-	-	-
HFBFALPA_00133	2.66e-64	-	-	-	-	-	-	-	-
HFBFALPA_00134	1.75e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HFBFALPA_00135	6.7e-200	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFBFALPA_00136	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFBFALPA_00137	3.96e-49	-	-	-	-	-	-	-	-
HFBFALPA_00138	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFBFALPA_00139	1.38e-73	-	-	-	M	ko:K02004	-	ko00000,ko00002,ko02000	Membrane
HFBFALPA_00140	1.48e-159	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_00141	6.21e-270	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFBFALPA_00142	1.17e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFBFALPA_00143	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
HFBFALPA_00144	9.86e-153	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFBFALPA_00145	3.65e-156	-	-	-	-	-	-	-	-
HFBFALPA_00146	2.93e-299	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFBFALPA_00147	8.72e-313	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HFBFALPA_00148	6.39e-177	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HFBFALPA_00149	9.15e-302	-	-	-	E	-	-	-	amino acid
HFBFALPA_00150	3e-308	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HFBFALPA_00152	2.87e-141	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFBFALPA_00153	1.13e-182	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFBFALPA_00154	9.53e-23	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HFBFALPA_00155	3.95e-41	-	-	-	S	-	-	-	HicB family
HFBFALPA_00156	1.61e-36	-	-	-	-	-	-	-	-
HFBFALPA_00157	3.27e-69	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HFBFALPA_00158	4.63e-184	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HFBFALPA_00159	2.23e-150	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HFBFALPA_00160	4.67e-163	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
HFBFALPA_00161	1.6e-287	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFBFALPA_00162	6.16e-243	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_00163	3.15e-99	-	-	-	-	-	-	-	-
HFBFALPA_00164	4.26e-128	-	-	-	-	-	-	-	-
HFBFALPA_00165	8.04e-228	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HFBFALPA_00166	1.02e-26	-	-	-	S	-	-	-	Enterocin A Immunity
HFBFALPA_00167	5.69e-195	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HFBFALPA_00168	7.43e-171	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HFBFALPA_00169	2.03e-222	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HFBFALPA_00170	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFBFALPA_00171	3.83e-163	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFBFALPA_00172	4.52e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFBFALPA_00174	5.13e-209	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HFBFALPA_00175	1.37e-306	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBFALPA_00176	1.17e-146	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_00177	2.71e-192	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
HFBFALPA_00178	4.08e-138	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_00179	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_00180	9.06e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFBFALPA_00181	1.09e-170	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_00182	5.33e-288	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFBFALPA_00183	1.19e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
HFBFALPA_00184	7.47e-229	-	-	-	EGP	-	-	-	Major facilitator superfamily
HFBFALPA_00185	1.41e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HFBFALPA_00186	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
HFBFALPA_00187	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_00188	1.25e-104	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HFBFALPA_00189	1.23e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBFALPA_00190	2.62e-166	-	-	-	F	-	-	-	glutamine amidotransferase
HFBFALPA_00191	6.54e-117	-	-	-	-	-	-	-	-
HFBFALPA_00192	3.97e-40	-	-	-	-	-	-	-	-
HFBFALPA_00193	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HFBFALPA_00194	7.25e-265	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
HFBFALPA_00195	2.3e-275	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
HFBFALPA_00196	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_00197	5.44e-116	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFBFALPA_00198	4.2e-301	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HFBFALPA_00199	3.04e-180	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HFBFALPA_00200	3.27e-211	-	-	-	L	ko:K07496	-	ko00000	Transposase
HFBFALPA_00201	1.47e-206	-	-	-	L	-	-	-	Transposase
HFBFALPA_00202	2.7e-278	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HFBFALPA_00203	3.06e-74	-	-	-	-	-	-	-	-
HFBFALPA_00204	1.96e-23	-	-	-	-	-	-	-	-
HFBFALPA_00205	1.55e-123	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HFBFALPA_00207	3.84e-70	-	-	-	-	-	-	-	-
HFBFALPA_00208	1.78e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFBFALPA_00209	1.33e-260	-	-	-	L	-	-	-	Probable transposase
HFBFALPA_00210	2.66e-57	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HFBFALPA_00211	1.51e-57	-	-	-	-	-	-	-	-
HFBFALPA_00212	4.71e-32	-	-	-	-	-	-	-	-
HFBFALPA_00213	1e-106	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
HFBFALPA_00214	6.31e-29	-	-	-	-	-	-	-	-
HFBFALPA_00215	3.3e-171	-	-	-	S	-	-	-	Peptidase_C39 like family
HFBFALPA_00216	2.16e-192	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HFBFALPA_00217	5.67e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HFBFALPA_00218	7.12e-111	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HFBFALPA_00219	1.24e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFBFALPA_00220	5.15e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HFBFALPA_00221	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFBFALPA_00222	2.42e-74	-	-	-	-	-	-	-	-
HFBFALPA_00223	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFBFALPA_00224	1.68e-229	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HFBFALPA_00225	1.67e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFBFALPA_00226	2.07e-65	-	-	-	-	-	-	-	-
HFBFALPA_00227	3.11e-28	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFBFALPA_00228	3.01e-191	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HFBFALPA_00229	2.16e-148	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFBFALPA_00230	5.66e-188	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFBFALPA_00231	2.98e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HFBFALPA_00232	8.79e-67	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFBFALPA_00233	2.19e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFBFALPA_00234	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFBFALPA_00235	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HFBFALPA_00236	2.69e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFBFALPA_00237	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HFBFALPA_00238	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFBFALPA_00239	3.15e-67	-	-	-	-	-	-	-	-
HFBFALPA_00240	2.03e-80	-	-	-	-	-	-	-	-
HFBFALPA_00241	5.24e-312	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFBFALPA_00242	1.56e-231	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HFBFALPA_00243	9.26e-270	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFBFALPA_00244	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFBFALPA_00245	1.42e-76	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFBFALPA_00246	4.17e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFBFALPA_00247	1.47e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFBFALPA_00248	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFBFALPA_00249	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFBFALPA_00250	5.78e-63	-	-	-	-	-	-	-	-
HFBFALPA_00251	4.31e-194	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HFBFALPA_00252	6.95e-184	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HFBFALPA_00253	9.97e-119	levB	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFBFALPA_00254	1.16e-87	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HFBFALPA_00270	1.84e-242	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_00271	1.37e-239	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HFBFALPA_00272	8.38e-109	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFBFALPA_00273	1.65e-205	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFBFALPA_00275	6.04e-189	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
HFBFALPA_00276	8.44e-24	-	-	-	S	-	-	-	Toxin ToxN, type III toxin-antitoxin system
HFBFALPA_00277	5.83e-161	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HFBFALPA_00278	3.83e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HFBFALPA_00279	1.09e-161	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFBFALPA_00280	4.95e-246	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFBFALPA_00281	6.27e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HFBFALPA_00282	1.33e-170	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HFBFALPA_00283	1.51e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFBFALPA_00284	6.78e-164	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HFBFALPA_00285	7.51e-198	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFBFALPA_00286	2.32e-79	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HFBFALPA_00287	1.9e-195	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFBFALPA_00288	6.21e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HFBFALPA_00289	8.08e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFBFALPA_00290	1.13e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HFBFALPA_00291	5.33e-141	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFBFALPA_00292	3.64e-58	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFBFALPA_00293	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFBFALPA_00294	1.53e-118	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFBFALPA_00295	1.02e-143	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HFBFALPA_00296	1.36e-121	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
HFBFALPA_00297	2.3e-36	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
HFBFALPA_00298	2.28e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFBFALPA_00299	6.16e-110	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFBFALPA_00300	4.39e-151	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFBFALPA_00301	2.66e-29	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFBFALPA_00302	5.28e-33	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFBFALPA_00303	1.43e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HFBFALPA_00304	3.28e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFBFALPA_00305	1.38e-182	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFBFALPA_00306	1.82e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HFBFALPA_00307	1.65e-219	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HFBFALPA_00308	1.1e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFBFALPA_00309	3.02e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFBFALPA_00310	3.82e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFBFALPA_00311	5e-130	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HFBFALPA_00312	8.53e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFBFALPA_00313	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFBFALPA_00314	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HFBFALPA_00315	2.41e-45	-	-	-	-	-	-	-	-
HFBFALPA_00316	4.1e-118	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HFBFALPA_00317	1.76e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFBFALPA_00318	7.88e-97	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFBFALPA_00319	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFBFALPA_00320	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFBFALPA_00321	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFBFALPA_00322	1.56e-132	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HFBFALPA_00323	5.04e-71	-	-	-	-	-	-	-	-
HFBFALPA_00327	4.54e-59	-	-	-	-	-	-	-	-
HFBFALPA_00328	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HFBFALPA_00329	4.84e-11	-	-	-	-	-	-	-	-
HFBFALPA_00330	1.33e-143	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HFBFALPA_00331	4.81e-62	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFBFALPA_00332	2.21e-99	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_00333	1.49e-252	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFBFALPA_00334	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HFBFALPA_00335	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HFBFALPA_00336	5.95e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HFBFALPA_00337	1.64e-261	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HFBFALPA_00338	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFBFALPA_00339	9.01e-89	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HFBFALPA_00340	5.2e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFBFALPA_00341	5.03e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFBFALPA_00342	5.59e-251	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFBFALPA_00343	6.25e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFBFALPA_00344	2.06e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFBFALPA_00345	4.01e-194	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HFBFALPA_00346	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HFBFALPA_00347	2.46e-102	-	-	-	S	-	-	-	ASCH
HFBFALPA_00348	1.64e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HFBFALPA_00349	5.6e-45	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFBFALPA_00350	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFBFALPA_00351	1.6e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFBFALPA_00352	2.87e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFBFALPA_00353	9.08e-187	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HFBFALPA_00354	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFBFALPA_00355	9.22e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFBFALPA_00356	1.63e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HFBFALPA_00357	1.06e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HFBFALPA_00358	1.98e-64	-	-	-	-	-	-	-	-
HFBFALPA_00359	3.82e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HFBFALPA_00360	1.67e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HFBFALPA_00361	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HFBFALPA_00362	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFBFALPA_00363	4.31e-232	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFBFALPA_00364	8.89e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFBFALPA_00365	2.11e-249	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBFALPA_00366	3.41e-231	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBFALPA_00367	7.39e-226	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_00368	1.56e-190	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBFALPA_00369	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFBFALPA_00370	5.01e-41	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HFBFALPA_00372	2.91e-91	-	-	-	L	-	-	-	transposase activity
HFBFALPA_00373	3.86e-27	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HFBFALPA_00374	4.46e-60	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFBFALPA_00375	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFBFALPA_00376	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFBFALPA_00377	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFBFALPA_00378	7.84e-106	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HFBFALPA_00382	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HFBFALPA_00383	9.65e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFBFALPA_00384	5.97e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFBFALPA_00385	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFBFALPA_00386	2.32e-305	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFBFALPA_00387	3.8e-80	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
HFBFALPA_00388	6.18e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HFBFALPA_00389	1.26e-46	yabO	-	-	J	-	-	-	S4 domain protein
HFBFALPA_00390	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFBFALPA_00391	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFBFALPA_00392	3.42e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFBFALPA_00393	8.34e-165	-	-	-	S	-	-	-	(CBS) domain
HFBFALPA_00394	1.04e-119	-	-	-	K	-	-	-	transcriptional regulator
HFBFALPA_00395	7.68e-275	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFBFALPA_00396	1.33e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFBFALPA_00397	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFBFALPA_00398	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFBFALPA_00399	5.28e-53	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HFBFALPA_00400	4.49e-194	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFBFALPA_00401	0.0	-	-	-	E	-	-	-	amino acid
HFBFALPA_00404	1.17e-29	repA	-	-	S	-	-	-	Replication initiator protein A
HFBFALPA_00405	3.8e-130	-	-	-	G	-	-	-	Aldose 1-epimerase
HFBFALPA_00406	8.94e-252	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFBFALPA_00407	2.52e-142	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFBFALPA_00408	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HFBFALPA_00409	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
HFBFALPA_00410	1.04e-308	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFBFALPA_00411	6.27e-24	-	-	-	-	-	-	-	-
HFBFALPA_00412	3.32e-37	-	-	-	-	-	-	-	-
HFBFALPA_00414	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HFBFALPA_00415	7.92e-151	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFBFALPA_00416	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFBFALPA_00417	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HFBFALPA_00418	1.21e-264	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFBFALPA_00419	6.08e-188	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBFALPA_00420	1.07e-237	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFBFALPA_00421	3.02e-253	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBFALPA_00422	5.37e-221	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBFALPA_00423	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HFBFALPA_00424	2.05e-94	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFBFALPA_00425	9.44e-99	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFBFALPA_00426	6.33e-148	-	-	-	-	-	-	-	-
HFBFALPA_00428	6.01e-147	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
HFBFALPA_00429	3.34e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFBFALPA_00430	5.22e-117	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
HFBFALPA_00431	4.56e-138	-	-	-	S	ko:K06872	-	ko00000	TPM domain
HFBFALPA_00432	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HFBFALPA_00433	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFBFALPA_00434	5.48e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HFBFALPA_00435	8.57e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFBFALPA_00436	9.89e-207	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFBFALPA_00437	4.69e-32	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFBFALPA_00438	2.57e-25	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFBFALPA_00439	1.62e-62	-	-	-	-	-	-	-	-
HFBFALPA_00440	4.46e-275	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HFBFALPA_00441	1.27e-273	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HFBFALPA_00442	5.86e-275	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HFBFALPA_00443	1.72e-214	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFBFALPA_00444	3.93e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HFBFALPA_00445	4.23e-212	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HFBFALPA_00446	5.77e-102	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HFBFALPA_00447	2.04e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HFBFALPA_00448	3.14e-276	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFBFALPA_00449	5.82e-35	-	-	-	-	-	-	-	-
HFBFALPA_00451	1.5e-310	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFBFALPA_00452	3.71e-265	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HFBFALPA_00453	6.35e-164	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFBFALPA_00454	2.75e-287	-	-	-	E	ko:K03294	-	ko00000	amino acid
HFBFALPA_00455	5.81e-131	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFBFALPA_00456	1.29e-312	yhdP	-	-	S	-	-	-	Transporter associated domain
HFBFALPA_00457	3.57e-34	-	-	-	C	-	-	-	nitroreductase
HFBFALPA_00458	2.85e-23	-	-	-	C	-	-	-	nitroreductase
HFBFALPA_00459	2.89e-52	-	-	-	-	-	-	-	-
HFBFALPA_00460	9.32e-112	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HFBFALPA_00461	1.06e-94	-	-	-	-	-	-	-	-
HFBFALPA_00462	3.43e-184	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HFBFALPA_00463	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFBFALPA_00464	2.23e-110	-	-	-	S	-	-	-	hydrolase
HFBFALPA_00465	2.65e-18	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFBFALPA_00466	1.59e-206	-	-	-	S	-	-	-	Phospholipase, patatin family
HFBFALPA_00467	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HFBFALPA_00468	6.48e-173	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HFBFALPA_00469	1.4e-74	-	-	-	S	-	-	-	Enterocin A Immunity
HFBFALPA_00470	1.51e-73	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFBFALPA_00471	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HFBFALPA_00472	1.07e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HFBFALPA_00473	6.39e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFBFALPA_00474	4.53e-301	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HFBFALPA_00475	2.13e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HFBFALPA_00476	4.69e-32	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFBFALPA_00477	3.44e-57	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFBFALPA_00478	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HFBFALPA_00479	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFBFALPA_00480	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HFBFALPA_00481	2.04e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HFBFALPA_00482	3.19e-263	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFBFALPA_00483	1.02e-277	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBFALPA_00484	2.4e-312	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBFALPA_00485	3.99e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_00486	9.3e-56	ymdB	-	-	S	-	-	-	Macro domain protein
HFBFALPA_00487	7.07e-38	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HFBFALPA_00489	6.51e-83	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFBFALPA_00490	2.11e-191	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFBFALPA_00491	2.59e-86	-	-	-	L	-	-	-	Transposase
HFBFALPA_00492	2.87e-53	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFBFALPA_00493	4.43e-105	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFBFALPA_00494	4.92e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HFBFALPA_00495	1.81e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFBFALPA_00496	6.74e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFBFALPA_00497	1.3e-202	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFBFALPA_00498	9.06e-156	-	-	-	L	-	-	-	Transposase DDE domain
HFBFALPA_00499	3.96e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFBFALPA_00500	3.37e-291	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFBFALPA_00501	5.94e-127	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HFBFALPA_00502	2.18e-172	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HFBFALPA_00503	5.89e-234	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFBFALPA_00504	6.36e-26	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HFBFALPA_00505	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFBFALPA_00506	6.74e-267	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFBFALPA_00507	1.28e-276	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HFBFALPA_00508	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HFBFALPA_00509	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFBFALPA_00510	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFBFALPA_00511	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFBFALPA_00512	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFBFALPA_00513	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFBFALPA_00514	7.57e-109	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HFBFALPA_00515	2.09e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HFBFALPA_00516	1.27e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HFBFALPA_00517	8.23e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HFBFALPA_00518	4.53e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFBFALPA_00519	0.0	-	-	-	S	-	-	-	SH3-like domain
HFBFALPA_00520	8.38e-192	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFBFALPA_00521	0.0	ycaM	-	-	E	-	-	-	amino acid
HFBFALPA_00522	1.04e-150	-	-	-	-	-	-	-	-
HFBFALPA_00523	2.99e-82	-	-	-	-	-	-	-	-
HFBFALPA_00524	2.76e-68	-	-	-	-	-	-	-	-
HFBFALPA_00526	6.71e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HFBFALPA_00527	1.16e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFBFALPA_00528	6.01e-288	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HFBFALPA_00529	2.71e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFBFALPA_00530	3.58e-124	-	-	-	-	-	-	-	-
HFBFALPA_00531	1.15e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFBFALPA_00532	7.79e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFBFALPA_00533	5.23e-231	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HFBFALPA_00534	1.87e-118	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HFBFALPA_00535	7.47e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFBFALPA_00536	1.71e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HFBFALPA_00537	9.1e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFBFALPA_00538	5.95e-176	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_00539	3.09e-178	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_00540	3.71e-261	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBFALPA_00541	5.87e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFBFALPA_00542	2.51e-216	ybbR	-	-	S	-	-	-	YbbR-like protein
HFBFALPA_00543	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFBFALPA_00544	2.4e-191	-	-	-	S	-	-	-	hydrolase
HFBFALPA_00545	8.04e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HFBFALPA_00546	3.74e-153	-	-	-	-	-	-	-	-
HFBFALPA_00547	2.06e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFBFALPA_00548	3.38e-273	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFBFALPA_00549	1.14e-175	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HFBFALPA_00550	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBFALPA_00551	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBFALPA_00552	9.83e-235	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HFBFALPA_00553	0.0	-	-	-	E	-	-	-	Amino acid permease
HFBFALPA_00555	9.51e-119	-	-	-	S	-	-	-	VanZ like family
HFBFALPA_00556	2.3e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HFBFALPA_00557	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HFBFALPA_00558	1.86e-222	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HFBFALPA_00559	6.9e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HFBFALPA_00560	2.04e-95	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
HFBFALPA_00561	1.18e-55	-	-	-	-	-	-	-	-
HFBFALPA_00562	9.9e-105	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HFBFALPA_00563	4.89e-238	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HFBFALPA_00564	3.05e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFBFALPA_00566	2.64e-50	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HFBFALPA_00567	1.64e-40	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HFBFALPA_00568	3.87e-284	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HFBFALPA_00569	9.25e-221	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFBFALPA_00570	5.73e-80	-	-	-	S	-	-	-	SdpI/YhfL protein family
HFBFALPA_00571	4.46e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HFBFALPA_00572	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HFBFALPA_00573	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFBFALPA_00574	1.3e-139	vanZ	-	-	V	-	-	-	VanZ like family
HFBFALPA_00575	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HFBFALPA_00576	1.89e-19	-	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_00577	5.35e-159	-	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_00578	4.84e-50	-	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_00579	2.36e-247	ampC	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_00582	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HFBFALPA_00583	4.94e-146	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HFBFALPA_00584	7.36e-234	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFBFALPA_00585	2.42e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFBFALPA_00586	7.56e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFBFALPA_00587	2.15e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFBFALPA_00588	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HFBFALPA_00589	4.83e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFBFALPA_00590	4.97e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFBFALPA_00591	1.54e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFBFALPA_00592	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFBFALPA_00593	8.2e-219	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFBFALPA_00594	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFBFALPA_00595	4.95e-93	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFBFALPA_00596	4.22e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HFBFALPA_00597	7.96e-226	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HFBFALPA_00598	4.39e-66	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HFBFALPA_00599	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HFBFALPA_00600	6.85e-275	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HFBFALPA_00601	9.45e-104	uspA	-	-	T	-	-	-	universal stress protein
HFBFALPA_00602	4.53e-55	-	-	-	-	-	-	-	-
HFBFALPA_00603	6.53e-307	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFBFALPA_00604	5.05e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFBFALPA_00605	2.95e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFBFALPA_00606	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFBFALPA_00607	8.68e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFBFALPA_00608	7.99e-294	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFBFALPA_00609	3.61e-178	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBFALPA_00610	5.21e-164	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFBFALPA_00611	2.95e-21	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBFALPA_00612	9.39e-85	-	-	-	-	-	-	-	-
HFBFALPA_00613	3.43e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
HFBFALPA_00614	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFBFALPA_00615	3.55e-39	-	-	-	-	-	-	-	-
HFBFALPA_00616	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HFBFALPA_00617	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFBFALPA_00618	4.42e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFBFALPA_00619	2.5e-176	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFBFALPA_00620	1.08e-203	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFBFALPA_00621	5.3e-144	yjbH	-	-	Q	-	-	-	Thioredoxin
HFBFALPA_00622	6.91e-139	-	-	-	S	-	-	-	CYTH
HFBFALPA_00623	1.63e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HFBFALPA_00624	2.52e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFBFALPA_00625	6.77e-216	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFBFALPA_00626	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HFBFALPA_00627	2.05e-88	-	-	-	S	-	-	-	SNARE associated Golgi protein
HFBFALPA_00628	4.12e-255	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HFBFALPA_00629	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HFBFALPA_00630	2.72e-85	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HFBFALPA_00631	1.16e-267	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HFBFALPA_00632	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFBFALPA_00633	4.46e-90	WQ51_03320	-	-	S	-	-	-	Protein of unknown function (DUF1149)
HFBFALPA_00634	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFBFALPA_00635	4.05e-289	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HFBFALPA_00636	1.85e-301	ymfH	-	-	S	-	-	-	Peptidase M16
HFBFALPA_00637	1.89e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HFBFALPA_00638	1.33e-186	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HFBFALPA_00639	3e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFBFALPA_00640	8.51e-246	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFBFALPA_00641	5.81e-284	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HFBFALPA_00642	1.01e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HFBFALPA_00643	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HFBFALPA_00644	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HFBFALPA_00645	1.83e-264	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFBFALPA_00647	7.13e-227	lipA	-	-	I	-	-	-	Carboxylesterase family
HFBFALPA_00648	1.55e-87	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HFBFALPA_00649	7.87e-37	-	-	-	-	-	-	-	-
HFBFALPA_00650	1.54e-74	-	-	-	S	-	-	-	Bacterial PH domain
HFBFALPA_00651	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFBFALPA_00652	2.21e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HFBFALPA_00653	1.06e-62	-	-	-	-	-	-	-	-
HFBFALPA_00654	1.78e-175	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HFBFALPA_00656	1.29e-53	-	-	-	-	-	-	-	-
HFBFALPA_00657	8.27e-09	-	-	-	-	-	-	-	-
HFBFALPA_00658	3.46e-07	-	-	-	M	-	-	-	Mycoplasma protein of unknown function, DUF285
HFBFALPA_00659	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFBFALPA_00660	1.3e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFBFALPA_00661	1.93e-302	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFBFALPA_00662	1.56e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFBFALPA_00663	1.38e-120	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFBFALPA_00664	5.1e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFBFALPA_00665	2.78e-158	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFBFALPA_00666	2.51e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFBFALPA_00667	2.95e-236	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFBFALPA_00668	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFBFALPA_00669	5.43e-296	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HFBFALPA_00671	2.07e-56	-	-	-	O	-	-	-	Matrixin
HFBFALPA_00672	5.02e-69	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
HFBFALPA_00673	6.62e-163	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_00674	1.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFBFALPA_00675	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFBFALPA_00676	1.98e-193	-	-	-	-	-	-	-	-
HFBFALPA_00677	6.72e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFBFALPA_00678	1.6e-278	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFBFALPA_00679	5.7e-299	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFBFALPA_00680	1.31e-135	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HFBFALPA_00681	0.0	potE	-	-	E	-	-	-	Amino Acid
HFBFALPA_00682	5.52e-240	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFBFALPA_00683	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFBFALPA_00684	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFBFALPA_00685	2.94e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFBFALPA_00686	2.32e-280	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFBFALPA_00687	3.65e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFBFALPA_00688	3.67e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFBFALPA_00689	3.01e-272	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFBFALPA_00690	1.43e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFBFALPA_00691	1.06e-260	pbpX1	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_00692	1.43e-134	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HFBFALPA_00693	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
HFBFALPA_00694	2.91e-47	-	-	-	C	-	-	-	FMN_bind
HFBFALPA_00695	2.6e-107	-	-	-	-	-	-	-	-
HFBFALPA_00696	6.22e-127	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HFBFALPA_00697	3.96e-74	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
HFBFALPA_00698	3.48e-36	ydhF	-	-	S	-	-	-	Aldo keto reductase
HFBFALPA_00699	9.89e-35	ydhF	-	-	S	-	-	-	Aldo keto reductase
HFBFALPA_00700	2.48e-64	ydhF	-	-	S	-	-	-	Aldo keto reductase
HFBFALPA_00701	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBFALPA_00702	1.61e-138	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
HFBFALPA_00703	9.69e-72	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HFBFALPA_00704	2.12e-77	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HFBFALPA_00705	5.74e-38	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_00706	2.59e-31	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_00707	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFBFALPA_00708	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFBFALPA_00709	9.05e-254	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HFBFALPA_00710	1.62e-189	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HFBFALPA_00711	2.23e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFBFALPA_00712	8.57e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFBFALPA_00713	2.38e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HFBFALPA_00714	2.15e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFBFALPA_00715	1.1e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HFBFALPA_00716	4.99e-252	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HFBFALPA_00717	1.46e-145	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HFBFALPA_00718	9.59e-289	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HFBFALPA_00719	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFBFALPA_00720	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBFALPA_00721	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBFALPA_00722	6.43e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HFBFALPA_00723	1.85e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
HFBFALPA_00724	1.15e-144	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFBFALPA_00725	5.3e-189	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HFBFALPA_00726	1.56e-152	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HFBFALPA_00727	1.32e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFBFALPA_00728	5.68e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HFBFALPA_00729	1.64e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFBFALPA_00730	2.36e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HFBFALPA_00731	4.67e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFBFALPA_00732	1.17e-73	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFBFALPA_00733	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HFBFALPA_00734	1.28e-50	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFBFALPA_00735	6.72e-289	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFBFALPA_00736	1.18e-165	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HFBFALPA_00739	4.49e-50	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFBFALPA_00740	6.62e-178	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
HFBFALPA_00741	4.75e-80	-	-	-	-	-	-	-	-
HFBFALPA_00742	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
HFBFALPA_00743	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
HFBFALPA_00744	0.0	-	-	-	S	-	-	-	TerB-C domain
HFBFALPA_00745	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HFBFALPA_00746	1.77e-93	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
HFBFALPA_00747	1.85e-48	-	-	-	-	-	-	-	-
HFBFALPA_00748	1.75e-137	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HFBFALPA_00749	5.06e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFBFALPA_00750	1.01e-102	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
HFBFALPA_00751	1e-113	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFBFALPA_00752	3.3e-55	-	-	-	-	-	-	-	-
HFBFALPA_00753	3.29e-127	-	-	-	E	-	-	-	amino acid
HFBFALPA_00754	1.48e-21	-	-	-	-	-	-	-	-
HFBFALPA_00755	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFBFALPA_00756	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HFBFALPA_00757	1.11e-299	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HFBFALPA_00758	4.68e-110	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HFBFALPA_00759	2.36e-93	-	-	-	K	-	-	-	Transcriptional regulator
HFBFALPA_00760	9.25e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
HFBFALPA_00761	3.37e-220	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HFBFALPA_00762	2.99e-180	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HFBFALPA_00763	1.52e-238	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HFBFALPA_00765	1.56e-156	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HFBFALPA_00766	7.28e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFBFALPA_00767	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFBFALPA_00768	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFBFALPA_00769	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HFBFALPA_00770	3.29e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFBFALPA_00771	2.23e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HFBFALPA_00772	3.16e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFBFALPA_00773	1.91e-196	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFBFALPA_00774	2.94e-60	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFBFALPA_00775	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFBFALPA_00776	3.03e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFBFALPA_00777	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFBFALPA_00778	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HFBFALPA_00779	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFBFALPA_00780	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFBFALPA_00781	6.92e-45	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFBFALPA_00782	2.9e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFBFALPA_00783	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFBFALPA_00784	2.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFBFALPA_00785	5.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFBFALPA_00786	1.05e-72	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFBFALPA_00787	2.63e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFBFALPA_00788	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HFBFALPA_00789	1.73e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HFBFALPA_00790	7.24e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFBFALPA_00791	2.61e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFBFALPA_00792	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFBFALPA_00793	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HFBFALPA_00794	1.46e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFBFALPA_00795	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFBFALPA_00796	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFBFALPA_00797	3.16e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HFBFALPA_00798	2.69e-195	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFBFALPA_00799	1.45e-190	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFBFALPA_00800	5.22e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFBFALPA_00801	3.02e-183	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFBFALPA_00802	1.87e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFBFALPA_00803	1.01e-87	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HFBFALPA_00804	3.32e-93	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
HFBFALPA_00805	1.22e-139	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HFBFALPA_00806	1.63e-81	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFBFALPA_00807	3.13e-173	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFBFALPA_00808	6.64e-162	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HFBFALPA_00809	5.3e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HFBFALPA_00810	4.73e-31	-	-	-	-	-	-	-	-
HFBFALPA_00811	1.98e-163	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFBFALPA_00812	1.91e-233	-	-	-	S	-	-	-	AAA domain
HFBFALPA_00813	1.67e-105	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFBFALPA_00814	6.3e-308	-	-	-	S	-	-	-	LPXTG cell wall anchor motif
HFBFALPA_00815	5.71e-192	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HFBFALPA_00816	3.65e-128	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
HFBFALPA_00817	6.12e-112	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HFBFALPA_00818	4.63e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HFBFALPA_00819	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HFBFALPA_00820	3.31e-221	ydbI	-	-	K	-	-	-	AI-2E family transporter
HFBFALPA_00821	1.08e-131	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFBFALPA_00822	4.97e-24	-	-	-	-	-	-	-	-
HFBFALPA_00823	3.14e-53	-	-	-	-	-	-	-	-
HFBFALPA_00824	4.93e-166	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_00825	2.25e-166	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFBFALPA_00826	1.78e-218	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HFBFALPA_00827	6.34e-172	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFBFALPA_00828	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HFBFALPA_00829	2.03e-184	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
HFBFALPA_00830	5.85e-38	-	-	-	-	-	-	-	-
HFBFALPA_00831	6.49e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFBFALPA_00832	3.77e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HFBFALPA_00833	1.03e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFBFALPA_00834	2.12e-43	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HFBFALPA_00835	6.11e-262	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HFBFALPA_00836	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HFBFALPA_00837	2.55e-246	pbpX1	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_00838	8.45e-92	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFBFALPA_00839	3.09e-52	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFBFALPA_00840	6.2e-53	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFBFALPA_00841	4.52e-62	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFBFALPA_00842	8.99e-99	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HFBFALPA_00843	3.29e-232	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFBFALPA_00844	2.2e-70	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HFBFALPA_00845	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFBFALPA_00846	5.4e-225	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFBFALPA_00847	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFBFALPA_00848	9.95e-267	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFBFALPA_00849	2.83e-181	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFBFALPA_00850	4.95e-305	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFBFALPA_00851	5.53e-262	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFBFALPA_00852	1.04e-94	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFBFALPA_00853	5.07e-62	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HFBFALPA_00854	1.1e-189	ylmH	-	-	S	-	-	-	S4 domain protein
HFBFALPA_00855	4.81e-163	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HFBFALPA_00856	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFBFALPA_00857	1.15e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HFBFALPA_00858	3.64e-134	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HFBFALPA_00859	2.13e-55	-	-	-	-	-	-	-	-
HFBFALPA_00860	1.69e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFBFALPA_00861	1.28e-273	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HFBFALPA_00862	2.01e-74	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HFBFALPA_00863	3.28e-280	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFBFALPA_00864	7.2e-158	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
HFBFALPA_00865	1.82e-144	-	-	-	S	-	-	-	repeat protein
HFBFALPA_00866	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFBFALPA_00870	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HFBFALPA_00871	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFBFALPA_00872	4.08e-47	-	-	-	-	-	-	-	-
HFBFALPA_00873	4.88e-131	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_00874	1.46e-240	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFBFALPA_00875	3.21e-208	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFBFALPA_00876	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HFBFALPA_00877	2.08e-21	ps301	-	-	K	-	-	-	sequence-specific DNA binding
HFBFALPA_00878	1.92e-123	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFBFALPA_00879	1.3e-239	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFBFALPA_00880	2.72e-314	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HFBFALPA_00882	5.43e-48	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFBFALPA_00883	2.94e-117	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFBFALPA_00884	1.26e-126	-	-	-	I	-	-	-	PAP2 superfamily
HFBFALPA_00885	3.59e-164	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFBFALPA_00886	1.23e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFBFALPA_00887	2.3e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HFBFALPA_00888	3.93e-109	yfhC	-	-	C	-	-	-	nitroreductase
HFBFALPA_00889	3.61e-157	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HFBFALPA_00890	9.89e-278	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBFALPA_00891	8.42e-85	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBFALPA_00892	1.88e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HFBFALPA_00893	6.67e-40	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
HFBFALPA_00894	6.29e-307	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFBFALPA_00895	9.69e-100	-	-	-	-	-	-	-	-
HFBFALPA_00896	1.45e-92	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HFBFALPA_00897	1.01e-24	-	-	-	-	-	-	-	-
HFBFALPA_00898	4.46e-190	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HFBFALPA_00899	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_00900	1.8e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HFBFALPA_00901	2.72e-85	-	-	-	S	-	-	-	Domain of unknown function DUF1828
HFBFALPA_00902	2.48e-69	-	-	-	-	-	-	-	-
HFBFALPA_00903	2.82e-214	citR	-	-	K	-	-	-	Putative sugar-binding domain
HFBFALPA_00904	1.38e-309	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFBFALPA_00905	1.42e-123	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HFBFALPA_00906	3.71e-34	-	-	-	-	ko:K14201	ko05150,map05150	ko00000,ko00001	-
HFBFALPA_00908	3.91e-26	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFBFALPA_00910	1.52e-114	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFBFALPA_00911	7.07e-222	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HFBFALPA_00912	8.96e-79	-	-	-	-	-	-	-	-
HFBFALPA_00913	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFBFALPA_00914	1.43e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFBFALPA_00915	4.28e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HFBFALPA_00916	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFBFALPA_00917	4.39e-281	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFBFALPA_00919	1.24e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFBFALPA_00920	1.26e-76	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_00921	8.01e-107	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HFBFALPA_00922	6.69e-264	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HFBFALPA_00923	9.2e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HFBFALPA_00924	5.4e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HFBFALPA_00925	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFBFALPA_00926	4.6e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFBFALPA_00927	6.73e-211	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFBFALPA_00928	6.52e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFBFALPA_00929	1.19e-237	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFBFALPA_00930	2.79e-115	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFBFALPA_00931	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HFBFALPA_00932	3.62e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFBFALPA_00933	1.13e-30	-	-	-	-	-	-	-	-
HFBFALPA_00934	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFBFALPA_00935	1.31e-149	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HFBFALPA_00936	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HFBFALPA_00937	8.09e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFBFALPA_00938	1.32e-148	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFBFALPA_00939	5.75e-40	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFBFALPA_00940	3.84e-189	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HFBFALPA_00941	1.65e-77	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFBFALPA_00942	2.22e-116	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFBFALPA_00943	3.42e-73	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFBFALPA_00944	1.78e-107	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
HFBFALPA_00945	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HFBFALPA_00946	9.46e-200	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HFBFALPA_00947	8.99e-261	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HFBFALPA_00948	7.26e-242	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFBFALPA_00949	3.13e-208	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HFBFALPA_00950	2.22e-125	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HFBFALPA_00951	1.68e-275	-	-	-	S	-	-	-	Sterol carrier protein domain
HFBFALPA_00952	6.5e-26	-	-	-	-	-	-	-	-
HFBFALPA_00953	5.96e-135	-	-	-	K	-	-	-	LysR substrate binding domain
HFBFALPA_00954	2.13e-77	-	-	-	-	-	-	-	-
HFBFALPA_00955	1.55e-18	-	-	-	-	-	-	-	-
HFBFALPA_00956	6.4e-131	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HFBFALPA_00957	2.22e-157	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFBFALPA_00958	2.15e-72	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFBFALPA_00959	2.62e-307	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HFBFALPA_00960	4.13e-154	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HFBFALPA_00961	3.33e-30	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HFBFALPA_00962	5.13e-05	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFBFALPA_00963	9.16e-80	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFBFALPA_00964	1.11e-50	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFBFALPA_00965	6.82e-138	-	-	-	-	-	-	-	-
HFBFALPA_00966	6.96e-206	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFBFALPA_00967	4.2e-115	-	-	-	S	-	-	-	Peptidase family M23
HFBFALPA_00968	7.77e-196	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFBFALPA_00969	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HFBFALPA_00970	1.21e-89	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HFBFALPA_00971	2.03e-223	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HFBFALPA_00972	2.33e-125	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFBFALPA_00973	1.48e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFBFALPA_00974	1.09e-172	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HFBFALPA_00975	5.4e-227	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HFBFALPA_00976	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HFBFALPA_00977	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFBFALPA_00978	7.08e-252	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFBFALPA_00979	1.4e-159	-	-	-	S	-	-	-	Peptidase family M23
HFBFALPA_00980	6.48e-89	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HFBFALPA_00981	2.49e-158	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HFBFALPA_00982	4.9e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFBFALPA_00983	4.94e-308	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFBFALPA_00984	7.06e-81	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HFBFALPA_00985	1.81e-159	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFBFALPA_00986	8.47e-181	-	-	-	-	-	-	-	-
HFBFALPA_00987	1.36e-179	-	-	-	-	-	-	-	-
HFBFALPA_00988	3.13e-173	-	-	-	-	-	-	-	-
HFBFALPA_00989	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HFBFALPA_00990	7.83e-38	-	-	-	-	-	-	-	-
HFBFALPA_00991	2.67e-136	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFBFALPA_00992	9.13e-182	-	-	-	-	-	-	-	-
HFBFALPA_00993	3.38e-226	-	-	-	-	-	-	-	-
HFBFALPA_00994	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HFBFALPA_00995	2.7e-233	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFBFALPA_00996	1.1e-259	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HFBFALPA_00997	1.18e-227	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HFBFALPA_00998	5.73e-210	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
HFBFALPA_00999	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFBFALPA_01000	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HFBFALPA_01001	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HFBFALPA_01002	6.04e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HFBFALPA_01003	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HFBFALPA_01004	1.39e-148	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HFBFALPA_01005	5.96e-146	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFBFALPA_01006	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HFBFALPA_01007	3.58e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFBFALPA_01008	1.54e-135	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HFBFALPA_01009	1.51e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFBFALPA_01010	2.79e-276	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HFBFALPA_01011	1.07e-294	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFBFALPA_01012	1.04e-61	-	-	-	S	-	-	-	Domain of unknown function (DUF4160)
HFBFALPA_01013	2.26e-68	-	-	-	-	-	-	-	-
HFBFALPA_01014	5.11e-258	-	-	-	G	-	-	-	Major Facilitator Superfamily
HFBFALPA_01015	9.89e-64	-	-	-	-	-	-	-	-
HFBFALPA_01016	3.66e-123	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HFBFALPA_01017	3.36e-61	-	-	-	-	-	-	-	-
HFBFALPA_01018	3.41e-152	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HFBFALPA_01019	3.15e-198	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFBFALPA_01020	2.27e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFBFALPA_01021	2.63e-207	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFBFALPA_01022	9.75e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01023	9.35e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HFBFALPA_01024	4.13e-148	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HFBFALPA_01025	5.7e-44	-	-	-	-	-	-	-	-
HFBFALPA_01026	2.77e-30	-	-	-	-	-	-	-	-
HFBFALPA_01027	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFBFALPA_01029	1.38e-121	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01030	2.9e-69	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01031	2.02e-29	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
HFBFALPA_01032	2.44e-25	-	-	-	-	-	-	-	-
HFBFALPA_01033	0.0	-	-	-	L	-	-	-	Transposase
HFBFALPA_01034	1.16e-210	-	-	-	M	-	-	-	domain, Protein
HFBFALPA_01035	2.37e-20	-	-	-	-	-	-	-	-
HFBFALPA_01036	1.43e-45	-	2.1.1.113	-	L	ko:K00590	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HFBFALPA_01037	8.82e-108	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFBFALPA_01038	3.86e-186	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFBFALPA_01039	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFBFALPA_01040	2.09e-266	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HFBFALPA_01041	1.18e-156	vanR	-	-	K	-	-	-	response regulator
HFBFALPA_01042	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFBFALPA_01043	2.51e-298	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01044	4.53e-69	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01045	2.2e-177	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HFBFALPA_01046	1.97e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFBFALPA_01047	1.83e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HFBFALPA_01048	2.29e-196	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFBFALPA_01049	2.77e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HFBFALPA_01050	3.14e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFBFALPA_01051	9.37e-169	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HFBFALPA_01052	2.12e-114	cvpA	-	-	S	-	-	-	Colicin V production protein
HFBFALPA_01053	6.37e-231	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFBFALPA_01054	4.51e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFBFALPA_01055	1.05e-125	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HFBFALPA_01056	1.14e-123	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HFBFALPA_01057	1.18e-140	-	-	-	K	-	-	-	WHG domain
HFBFALPA_01058	1.03e-49	-	-	-	-	-	-	-	-
HFBFALPA_01059	4.51e-42	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_01060	1.63e-27	-	-	-	E	-	-	-	Hexapeptide repeat of succinyl-transferase
HFBFALPA_01061	4.48e-161	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HFBFALPA_01062	1.83e-47	-	-	-	-	-	-	-	-
HFBFALPA_01063	3.82e-44	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HFBFALPA_01064	9.57e-86	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HFBFALPA_01065	4.66e-101	-	2.7.8.12	GT2	S	ko:K09809,ko:K19427	-	ko00000,ko01000	Glycosyltransferase like family 2
HFBFALPA_01066	1.28e-61	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HFBFALPA_01067	1.92e-182	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFBFALPA_01068	5.09e-100	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HFBFALPA_01069	1.21e-108	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HFBFALPA_01070	2.32e-155	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
HFBFALPA_01071	1.15e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HFBFALPA_01072	1.47e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HFBFALPA_01073	8.47e-188	epsB	-	-	M	-	-	-	biosynthesis protein
HFBFALPA_01074	5.18e-250	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFBFALPA_01075	9.13e-283	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFBFALPA_01076	3.51e-12	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HFBFALPA_01077	2.53e-195	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HFBFALPA_01078	6.04e-200	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HFBFALPA_01079	3.06e-77	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HFBFALPA_01080	1.94e-125	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HFBFALPA_01081	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
HFBFALPA_01082	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
HFBFALPA_01083	1.63e-79	-	-	-	-	-	-	-	-
HFBFALPA_01084	4.35e-31	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HFBFALPA_01085	5.03e-20	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HFBFALPA_01086	9.66e-46	-	-	-	-	-	-	-	-
HFBFALPA_01087	0.0	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFBFALPA_01088	1.58e-202	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HFBFALPA_01089	3.35e-74	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HFBFALPA_01090	1.18e-293	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFBFALPA_01091	3.35e-119	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HFBFALPA_01092	3.04e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HFBFALPA_01093	2.52e-263	-	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_01094	8.48e-145	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HFBFALPA_01095	9.85e-147	-	-	-	I	-	-	-	Acid phosphatase homologues
HFBFALPA_01096	1.26e-101	-	-	-	C	-	-	-	Flavodoxin
HFBFALPA_01097	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HFBFALPA_01098	1.74e-87	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HFBFALPA_01101	1.37e-214	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFBFALPA_01104	5.04e-278	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFBFALPA_01105	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_01106	4.22e-186	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFBFALPA_01107	2.45e-151	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HFBFALPA_01108	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HFBFALPA_01109	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFBFALPA_01110	9.71e-228	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HFBFALPA_01111	2.96e-30	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HFBFALPA_01112	2.74e-81	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HFBFALPA_01113	6.68e-29	-	-	-	-	-	-	-	-
HFBFALPA_01114	1.04e-76	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
HFBFALPA_01115	8.05e-149	-	-	-	K	-	-	-	Rhodanese Homology Domain
HFBFALPA_01116	4.43e-221	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFBFALPA_01117	4.81e-21	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HFBFALPA_01118	2.26e-17	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HFBFALPA_01119	1.94e-55	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HFBFALPA_01120	6.11e-37	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFBFALPA_01121	1.02e-196	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Quinolinate phosphoribosyl transferase, C-terminal domain
HFBFALPA_01122	3.03e-277	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HFBFALPA_01123	2.03e-170	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HFBFALPA_01124	2.53e-31	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HFBFALPA_01125	8.2e-102	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFBFALPA_01126	2.06e-103	-	-	-	K	-	-	-	Transcriptional regulator
HFBFALPA_01127	3.02e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFBFALPA_01128	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFBFALPA_01129	1.66e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HFBFALPA_01130	1.8e-163	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HFBFALPA_01131	8.97e-293	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFBFALPA_01132	5.23e-102	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFBFALPA_01133	1.64e-94	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HFBFALPA_01134	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HFBFALPA_01135	5.09e-202	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFBFALPA_01136	7.44e-183	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HFBFALPA_01137	8.96e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HFBFALPA_01138	2.25e-241	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFBFALPA_01139	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HFBFALPA_01140	6.1e-113	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_01141	1.02e-103	dltr	-	-	K	-	-	-	response regulator
HFBFALPA_01142	7.85e-156	sptS	-	-	T	-	-	-	Histidine kinase
HFBFALPA_01143	2.78e-71	sptS	-	-	T	-	-	-	Histidine kinase
HFBFALPA_01144	1.07e-263	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFBFALPA_01145	1.79e-92	-	-	-	O	-	-	-	OsmC-like protein
HFBFALPA_01146	1.05e-162	-	-	-	S	-	-	-	L-ascorbic acid biosynthetic process
HFBFALPA_01147	3.36e-137	-	-	-	-	-	-	-	-
HFBFALPA_01148	2.7e-154	-	-	-	-	-	-	-	-
HFBFALPA_01149	4.56e-120	-	-	-	-	-	-	-	-
HFBFALPA_01150	1.31e-295	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HFBFALPA_01151	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
HFBFALPA_01152	2.22e-165	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFBFALPA_01153	7.77e-166	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HFBFALPA_01154	3.2e-201	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFBFALPA_01155	9.99e-12	-	-	-	-	-	-	-	-
HFBFALPA_01156	1.18e-168	-	-	-	-	-	-	-	-
HFBFALPA_01157	6.65e-216	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFBFALPA_01158	3.17e-60	-	-	-	-	-	-	-	-
HFBFALPA_01159	2.55e-61	-	-	-	-	-	-	-	-
HFBFALPA_01160	1.15e-21	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFBFALPA_01161	3.17e-28	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HFBFALPA_01162	1.1e-277	-	-	-	EGP	ko:K08196,ko:K08369	-	ko00000,ko02000	Major Facilitator
HFBFALPA_01163	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFBFALPA_01164	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFBFALPA_01165	2.11e-271	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HFBFALPA_01166	5.96e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HFBFALPA_01168	4.02e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFBFALPA_01169	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HFBFALPA_01170	1.6e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HFBFALPA_01171	5.79e-217	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HFBFALPA_01172	0.0	-	-	-	S	-	-	-	membrane
HFBFALPA_01173	2.32e-203	-	-	-	S	-	-	-	membrane
HFBFALPA_01174	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFBFALPA_01175	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFBFALPA_01176	3.12e-129	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFBFALPA_01177	1.42e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
HFBFALPA_01178	2.45e-44	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HFBFALPA_01179	7.04e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HFBFALPA_01180	3.23e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFBFALPA_01181	4.76e-61	ynbB	-	-	P	-	-	-	aluminum resistance
HFBFALPA_01182	1.58e-109	ynbB	-	-	P	-	-	-	aluminum resistance
HFBFALPA_01183	7.4e-89	ynbB	-	-	P	-	-	-	aluminum resistance
HFBFALPA_01184	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HFBFALPA_01185	1.63e-173	-	-	-	-	-	-	-	-
HFBFALPA_01186	1.03e-207	-	-	-	-	-	-	-	-
HFBFALPA_01187	6.34e-201	-	-	-	-	-	-	-	-
HFBFALPA_01188	6.47e-25	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HFBFALPA_01189	3.5e-249	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HFBFALPA_01190	1.75e-256	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
HFBFALPA_01193	4.71e-233	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFBFALPA_01194	1.38e-313	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFBFALPA_01195	2.19e-307	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFBFALPA_01196	6.82e-74	-	-	-	-	-	-	-	-
HFBFALPA_01197	2.58e-108	-	-	-	-	-	-	-	-
HFBFALPA_01198	5.86e-39	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HFBFALPA_01199	2.18e-168	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HFBFALPA_01200	2.05e-130	-	-	-	S	-	-	-	DUF218 domain
HFBFALPA_01201	4.57e-75	-	-	-	S	-	-	-	DUF218 domain
HFBFALPA_01202	6.41e-101	-	-	-	-	-	-	-	-
HFBFALPA_01203	9.7e-140	-	-	-	-	-	-	-	-
HFBFALPA_01204	7.78e-190	-	-	-	EG	-	-	-	EamA-like transporter family
HFBFALPA_01205	6.89e-97	-	-	-	M	-	-	-	NlpC/P60 family
HFBFALPA_01206	1.36e-284	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
HFBFALPA_01207	2.23e-105	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HFBFALPA_01208	1.44e-188	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HFBFALPA_01209	8.14e-73	-	-	-	-	-	-	-	-
HFBFALPA_01210	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFBFALPA_01211	8.82e-113	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HFBFALPA_01212	3.89e-287	ptcC	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFBFALPA_01213	4.31e-179	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFBFALPA_01214	2.22e-67	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HFBFALPA_01215	4.77e-59	mgtC3	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HFBFALPA_01216	3.87e-12	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
HFBFALPA_01217	7.82e-204	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFBFALPA_01218	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFBFALPA_01219	2.07e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HFBFALPA_01220	5.59e-290	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HFBFALPA_01221	0.0	yhaN	-	-	L	-	-	-	AAA domain
HFBFALPA_01222	1.16e-241	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFBFALPA_01223	1.19e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HFBFALPA_01224	5.64e-200	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFBFALPA_01225	3.49e-56	-	-	-	-	-	-	-	-
HFBFALPA_01226	3.94e-103	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
HFBFALPA_01227	6.86e-72	-	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HFBFALPA_01228	9.02e-175	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01229	5.32e-268	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFBFALPA_01230	7.82e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFBFALPA_01231	1.64e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
HFBFALPA_01232	3.06e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFBFALPA_01233	0.0	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01234	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HFBFALPA_01235	2.38e-225	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01236	2.61e-76	-	-	-	M	-	-	-	Peptidase family M1 domain
HFBFALPA_01237	2.69e-178	-	-	-	M	-	-	-	Peptidase family M1 domain
HFBFALPA_01238	1.05e-47	-	-	-	M	-	-	-	Peptidase family M1 domain
HFBFALPA_01239	1.53e-246	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HFBFALPA_01240	3.05e-21	-	-	-	-	-	-	-	-
HFBFALPA_01241	1.87e-68	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HFBFALPA_01242	9.65e-193	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HFBFALPA_01243	3.72e-159	-	-	-	C	-	-	-	Flavodoxin
HFBFALPA_01244	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HFBFALPA_01245	3.23e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFBFALPA_01246	6.62e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFBFALPA_01247	7.17e-172	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HFBFALPA_01248	1.55e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFBFALPA_01249	5.48e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFBFALPA_01250	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFBFALPA_01251	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFBFALPA_01252	8.29e-252	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HFBFALPA_01253	1.78e-134	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFBFALPA_01254	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HFBFALPA_01255	1.31e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HFBFALPA_01256	0.0	-	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
HFBFALPA_01257	1.11e-184	cas5	-	-	S	ko:K19119	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HFBFALPA_01258	0.0	csd1	-	-	M	ko:K19117	-	ko00000,ko02048	CRISPR-associated protein (Cas_Csd1)
HFBFALPA_01259	5.5e-203	csd2	-	-	L	ko:K19115,ko:K19118	-	ko00000,ko02048	CRISPR-associated protein Cas7
HFBFALPA_01260	5.94e-161	cas4	3.1.12.1	-	L	ko:K07464	-	ko00000,ko01000,ko02048	Domain of unknown function DUF83
HFBFALPA_01261	5.83e-251	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFBFALPA_01262	2.86e-39	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFBFALPA_01263	2.56e-19	-	-	-	-	-	-	-	-
HFBFALPA_01264	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFBFALPA_01265	8.79e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFBFALPA_01266	5.94e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFBFALPA_01267	5.46e-108	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFBFALPA_01268	1.24e-314	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
HFBFALPA_01269	1.79e-213	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HFBFALPA_01270	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFBFALPA_01271	3.9e-79	-	-	-	S	ko:K09707	-	ko00000	ACT domain
HFBFALPA_01272	4.33e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
HFBFALPA_01273	3.29e-52	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HFBFALPA_01274	1.79e-242	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HFBFALPA_01275	2.8e-72	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFBFALPA_01276	4.77e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HFBFALPA_01277	1.23e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFBFALPA_01278	1.51e-121	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HFBFALPA_01279	4.77e-270	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HFBFALPA_01280	2.14e-154	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFBFALPA_01281	1.12e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HFBFALPA_01282	3.58e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFBFALPA_01283	2.57e-272	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HFBFALPA_01284	8.27e-124	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HFBFALPA_01285	3.37e-161	csrR	-	-	K	-	-	-	response regulator
HFBFALPA_01286	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBFALPA_01287	9.66e-110	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HFBFALPA_01288	1.17e-202	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFBFALPA_01289	9.28e-58	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HFBFALPA_01290	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFBFALPA_01291	1.4e-80	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HFBFALPA_01292	1.06e-256	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFBFALPA_01293	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFBFALPA_01294	2.74e-89	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFBFALPA_01295	9.25e-217	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
HFBFALPA_01296	1.18e-51	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBFALPA_01297	9.65e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HFBFALPA_01298	1.14e-177	-	-	-	S	-	-	-	Putative threonine/serine exporter
HFBFALPA_01299	0.0	-	-	-	S	-	-	-	ABC transporter
HFBFALPA_01300	2.34e-74	-	-	-	-	-	-	-	-
HFBFALPA_01301	1.89e-127	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFBFALPA_01302	6.66e-68	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFBFALPA_01303	4.9e-283	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HFBFALPA_01304	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HFBFALPA_01305	1.34e-34	-	-	-	S	-	-	-	Fic/DOC family
HFBFALPA_01306	1.12e-63	-	-	-	S	-	-	-	Fic/DOC family
HFBFALPA_01307	2.19e-56	-	-	-	S	-	-	-	Enterocin A Immunity
HFBFALPA_01308	1.22e-53	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFBFALPA_01309	6.39e-26	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFBFALPA_01310	4.15e-60	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFBFALPA_01311	1.12e-87	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFBFALPA_01312	1.34e-297	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFBFALPA_01313	9.17e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HFBFALPA_01314	9.45e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFBFALPA_01315	2.98e-201	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFBFALPA_01316	1.99e-39	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_01317	3.04e-154	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFBFALPA_01318	1.79e-248	-	-	-	S	-	-	-	DUF218 domain
HFBFALPA_01319	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01320	1.33e-126	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HFBFALPA_01321	2.08e-203	-	-	-	S	-	-	-	Aldo/keto reductase family
HFBFALPA_01322	7.74e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFBFALPA_01323	3.09e-128	-	-	-	K	-	-	-	rpiR family
HFBFALPA_01324	6.62e-180	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HFBFALPA_01325	5.12e-233	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Beta-lactamase
HFBFALPA_01326	1.01e-161	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFBFALPA_01327	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBFALPA_01328	6.43e-270	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01329	3.64e-224	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFBFALPA_01330	4.99e-189	-	-	-	GK	-	-	-	ROK family
HFBFALPA_01331	5.78e-57	-	-	-	-	-	-	-	-
HFBFALPA_01332	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFBFALPA_01333	3.92e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HFBFALPA_01334	4.53e-98	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFBFALPA_01335	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFBFALPA_01336	3e-309	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFBFALPA_01337	1.57e-97	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFBFALPA_01338	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFBFALPA_01339	1.16e-204	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
HFBFALPA_01340	2.54e-286	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HFBFALPA_01341	2.18e-132	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFBFALPA_01342	4.4e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
HFBFALPA_01343	1.29e-208	-	-	-	M	-	-	-	Glycosyl transferase family 8
HFBFALPA_01344	5.08e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
HFBFALPA_01345	4.24e-184	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
HFBFALPA_01346	1.86e-165	-	-	-	I	-	-	-	Acyl-transferase
HFBFALPA_01347	3.27e-38	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HFBFALPA_01348	1.34e-154	-	-	-	-	-	-	-	-
HFBFALPA_01350	9e-46	-	-	-	-	-	-	-	-
HFBFALPA_01352	2.3e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFBFALPA_01353	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFBFALPA_01354	8.07e-314	yycH	-	-	S	-	-	-	YycH protein
HFBFALPA_01355	3.54e-190	yycI	-	-	S	-	-	-	YycH protein
HFBFALPA_01356	8.73e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HFBFALPA_01357	1.18e-274	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HFBFALPA_01358	2.23e-117	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFBFALPA_01359	7.64e-62	-	-	-	-	-	-	-	-
HFBFALPA_01360	3.67e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HFBFALPA_01361	1.63e-118	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
HFBFALPA_01362	1.5e-32	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
HFBFALPA_01363	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HFBFALPA_01364	7.22e-262	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HFBFALPA_01365	1.1e-276	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFBFALPA_01366	3.65e-16	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HFBFALPA_01367	8.72e-12	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HFBFALPA_01369	5.71e-206	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01370	4.3e-49	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HFBFALPA_01371	7.02e-40	-	-	-	-	-	-	-	-
HFBFALPA_01372	8.86e-09	-	-	-	-	-	-	-	-
HFBFALPA_01374	1.63e-112	-	-	-	-	-	-	-	-
HFBFALPA_01375	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HFBFALPA_01376	1.24e-139	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFBFALPA_01377	2.23e-35	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFBFALPA_01378	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFBFALPA_01379	9e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HFBFALPA_01380	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFBFALPA_01381	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HFBFALPA_01382	3.86e-263	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFBFALPA_01383	1.72e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HFBFALPA_01384	5e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HFBFALPA_01385	6.77e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFBFALPA_01386	3.91e-245	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HFBFALPA_01387	9.86e-130	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HFBFALPA_01388	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFBFALPA_01389	4.76e-222	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HFBFALPA_01390	4.42e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HFBFALPA_01391	1.36e-267	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
HFBFALPA_01392	1.2e-87	-	-	-	S	-	-	-	GtrA-like protein
HFBFALPA_01393	1.47e-215	yfdH	-	GT2	M	ko:K12999,ko:K20534	-	ko00000,ko01000,ko01003,ko01005,ko02000	Glycosyltransferase like family 2
HFBFALPA_01394	4.99e-71	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HFBFALPA_01395	1.21e-106	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HFBFALPA_01396	1.92e-114	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HFBFALPA_01397	1.19e-130	-	-	-	-	ko:K19167	-	ko00000,ko02048	-
HFBFALPA_01398	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFBFALPA_01399	1.25e-302	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFBFALPA_01400	4.33e-162	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HFBFALPA_01401	3.32e-148	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HFBFALPA_01402	8.26e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HFBFALPA_01403	3.36e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HFBFALPA_01404	1.97e-124	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
HFBFALPA_01405	1.09e-18	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HFBFALPA_01406	8.66e-70	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HFBFALPA_01407	1.37e-152	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HFBFALPA_01408	1.44e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HFBFALPA_01409	8.01e-68	-	-	-	-	-	-	-	-
HFBFALPA_01410	1.12e-188	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HFBFALPA_01411	1.22e-289	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HFBFALPA_01412	7.55e-44	-	-	-	-	-	-	-	-
HFBFALPA_01413	4.58e-87	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HFBFALPA_01414	3.63e-80	kptA	-	-	H	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HFBFALPA_01415	2.02e-80	-	-	-	S	-	-	-	Abi-like protein
HFBFALPA_01417	1.11e-87	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HFBFALPA_01418	1.48e-127	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HFBFALPA_01419	3.88e-140	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HFBFALPA_01420	5.72e-12	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HFBFALPA_01421	9.41e-32	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HFBFALPA_01422	1.27e-142	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HFBFALPA_01423	2.95e-139	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HFBFALPA_01424	1.39e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01425	7.24e-205	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFBFALPA_01426	4.41e-78	-	-	-	L	-	-	-	Helix-turn-helix domain
HFBFALPA_01427	3.78e-64	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFBFALPA_01428	4.34e-100	-	-	-	KLT	-	-	-	serine threonine protein kinase
HFBFALPA_01429	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HFBFALPA_01430	0.0	-	-	-	L	-	-	-	Probable transposase
HFBFALPA_01431	3.57e-136	-	-	-	L	-	-	-	Resolvase, N terminal domain
HFBFALPA_01432	1.14e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HFBFALPA_01433	4.61e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFBFALPA_01434	6.34e-136	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HFBFALPA_01436	5.17e-08	-	-	-	S	-	-	-	Protein of unknown function (DUF3923)
HFBFALPA_01437	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HFBFALPA_01438	5.75e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFBFALPA_01439	2.17e-112	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFBFALPA_01442	1.31e-67	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HFBFALPA_01443	2.73e-60	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HFBFALPA_01444	4.69e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HFBFALPA_01445	6.39e-73	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBFALPA_01446	5.37e-143	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFBFALPA_01447	3.5e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HFBFALPA_01448	1.42e-217	-	-	-	K	-	-	-	Transcriptional regulator
HFBFALPA_01449	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFBFALPA_01450	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFBFALPA_01451	8.01e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFBFALPA_01452	4.14e-214	snf	-	-	KL	-	-	-	domain protein
HFBFALPA_01453	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HFBFALPA_01454	1.3e-121	-	-	-	K	-	-	-	acetyltransferase
HFBFALPA_01455	1.12e-42	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFBFALPA_01456	9.16e-123	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFBFALPA_01457	1.59e-86	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HFBFALPA_01458	1.43e-47	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HFBFALPA_01459	8.62e-75	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HFBFALPA_01460	6.31e-314	ynbB	-	-	P	-	-	-	aluminum resistance
HFBFALPA_01461	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
HFBFALPA_01462	0.0	-	-	-	E	-	-	-	Amino acid permease
HFBFALPA_01463	1.42e-60	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
HFBFALPA_01464	4.62e-37	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
HFBFALPA_01465	2.08e-84	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFBFALPA_01466	4.86e-84	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFBFALPA_01467	1.06e-194	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HFBFALPA_01468	2.43e-75	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFBFALPA_01469	3.16e-36	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HFBFALPA_01470	6.6e-28	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HFBFALPA_01471	1.41e-28	-	-	-	L	-	-	-	Transposase and inactivated derivatives
HFBFALPA_01472	1.35e-39	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HFBFALPA_01473	5e-32	-	-	-	-	-	-	-	-
HFBFALPA_01474	2.12e-224	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HFBFALPA_01475	1.49e-309	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFBFALPA_01476	1.15e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFBFALPA_01477	3.76e-215	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
HFBFALPA_01478	1.14e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFBFALPA_01479	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFBFALPA_01480	3.85e-198	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HFBFALPA_01481	1.09e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFBFALPA_01482	1.11e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFBFALPA_01483	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HFBFALPA_01484	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HFBFALPA_01485	1.37e-189	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HFBFALPA_01486	5.77e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HFBFALPA_01487	1.26e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFBFALPA_01488	7.21e-205	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFBFALPA_01489	1.87e-290	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HFBFALPA_01490	1.17e-56	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFBFALPA_01491	1.5e-311	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HFBFALPA_01492	8.97e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HFBFALPA_01493	1.81e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HFBFALPA_01494	1.09e-66	-	-	-	M	-	-	-	Lysin motif
HFBFALPA_01495	2.09e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFBFALPA_01496	3.14e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFBFALPA_01497	2.73e-133	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFBFALPA_01498	3e-168	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFBFALPA_01499	5.23e-77	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFBFALPA_01500	1.48e-216	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HFBFALPA_01501	2.98e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HFBFALPA_01502	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HFBFALPA_01503	6.65e-234	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFBFALPA_01504	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HFBFALPA_01505	2.72e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFBFALPA_01506	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFBFALPA_01507	3.62e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HFBFALPA_01508	7.74e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HFBFALPA_01509	1.13e-181	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFBFALPA_01510	3.02e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFBFALPA_01511	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HFBFALPA_01512	1.55e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFBFALPA_01513	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFBFALPA_01514	2.12e-80	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HFBFALPA_01515	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HFBFALPA_01516	6.35e-173	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFBFALPA_01517	2.84e-21	gyaR	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFBFALPA_01518	2.01e-178	yxeH	-	-	S	-	-	-	hydrolase
HFBFALPA_01519	6.12e-193	-	-	-	S	-	-	-	reductase
HFBFALPA_01520	4.04e-112	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HFBFALPA_01521	7.45e-120	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
HFBFALPA_01522	6.1e-64	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HFBFALPA_01524	1.86e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFBFALPA_01525	1.75e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFBFALPA_01526	7.45e-158	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFBFALPA_01527	1.19e-118	-	-	-	K	-	-	-	Virulence activator alpha C-term
HFBFALPA_01528	8.58e-139	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HFBFALPA_01529	1.03e-140	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFBFALPA_01530	5.02e-20	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HFBFALPA_01531	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HFBFALPA_01532	4.95e-216	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HFBFALPA_01533	5.65e-75	-	-	-	L	-	-	-	NUDIX domain
HFBFALPA_01534	5.88e-47	-	-	-	-	-	-	-	-
HFBFALPA_01535	5.42e-42	-	-	-	-	-	-	-	-
HFBFALPA_01537	3.61e-224	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFBFALPA_01538	2.41e-263	-	-	-	C	-	-	-	FAD binding domain
HFBFALPA_01539	6.28e-68	-	-	-	K	-	-	-	LysR substrate binding domain
HFBFALPA_01540	6.24e-18	-	-	-	K	-	-	-	LysR substrate binding domain
HFBFALPA_01541	1.44e-21	-	-	-	V	-	-	-	Abi-like protein
HFBFALPA_01542	8.68e-41	-	-	-	V	-	-	-	Abi-like protein
HFBFALPA_01544	2.36e-22	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HFBFALPA_01545	7.82e-10	-	-	-	V	-	-	-	Abi-like protein
HFBFALPA_01546	1.04e-20	-	-	-	V	-	-	-	Abi-like protein
HFBFALPA_01547	0.0	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HFBFALPA_01548	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFBFALPA_01549	1.84e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
HFBFALPA_01550	1.21e-124	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HFBFALPA_01551	4.65e-100	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01552	6.55e-221	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFBFALPA_01553	7.55e-123	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFBFALPA_01554	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01555	1e-220	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HFBFALPA_01556	3.17e-205	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HFBFALPA_01557	2.37e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HFBFALPA_01558	1.07e-245	ysdE	-	-	P	-	-	-	Citrate transporter
HFBFALPA_01559	1.36e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFBFALPA_01560	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HFBFALPA_01561	2.46e-184	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFBFALPA_01562	0.0	-	-	-	V	-	-	-	Restriction endonuclease
HFBFALPA_01563	3.74e-175	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFBFALPA_01564	3.39e-58	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFBFALPA_01565	7.86e-50	-	-	-	K	-	-	-	COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFBFALPA_01566	1.66e-168	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HFBFALPA_01567	3.84e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01568	1.21e-40	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HFBFALPA_01570	3.52e-311	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFBFALPA_01571	4.38e-196	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFBFALPA_01573	1.33e-55	-	-	-	O	-	-	-	RNA helicase
HFBFALPA_01574	7.07e-18	-	-	-	EP	-	-	-	Plasmid replication protein
HFBFALPA_01577	3.59e-264	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HFBFALPA_01578	1.14e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HFBFALPA_01579	6.08e-312	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HFBFALPA_01580	2.32e-169	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HFBFALPA_01581	6.59e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFBFALPA_01582	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFBFALPA_01583	8.41e-236	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFBFALPA_01584	5.54e-51	-	-	-	-	-	-	-	-
HFBFALPA_01585	2.39e-228	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFBFALPA_01586	1.35e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFBFALPA_01587	3.46e-241	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HFBFALPA_01588	2.31e-132	-	-	-	L	-	-	-	Integrase
HFBFALPA_01589	1.03e-61	-	-	-	-	-	-	-	-
HFBFALPA_01590	1.46e-110	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
HFBFALPA_01591	1.48e-72	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HFBFALPA_01592	8.74e-142	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HFBFALPA_01593	3.64e-24	-	-	-	-	-	-	-	-
HFBFALPA_01594	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFBFALPA_01595	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HFBFALPA_01596	1.39e-36	-	-	-	-	-	-	-	-
HFBFALPA_01597	3.47e-54	-	-	-	-	-	-	-	-
HFBFALPA_01598	7.53e-110	-	-	-	-	-	-	-	-
HFBFALPA_01599	4.88e-59	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HFBFALPA_01600	7.76e-218	repA	-	-	S	-	-	-	Replication initiator protein A
HFBFALPA_01601	9.39e-184	-	-	-	D	-	-	-	AAA domain
HFBFALPA_01602	4.07e-39	-	-	-	-	-	-	-	-
HFBFALPA_01604	4.56e-33	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HFBFALPA_01605	1.48e-49	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HFBFALPA_01606	1.87e-158	terC	-	-	P	-	-	-	Integral membrane protein TerC family
HFBFALPA_01607	2.78e-82	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HFBFALPA_01608	5.11e-158	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HFBFALPA_01609	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HFBFALPA_01610	2.38e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01611	3.72e-201	-	-	-	L	-	-	-	HNH nucleases
HFBFALPA_01612	2.94e-155	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HFBFALPA_01613	5.08e-190	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HFBFALPA_01614	2.09e-286	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HFBFALPA_01615	3.56e-180	-	-	-	-	-	-	-	-
HFBFALPA_01616	9.69e-25	-	-	-	-	-	-	-	-
HFBFALPA_01617	6.23e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFBFALPA_01618	4.53e-240	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HFBFALPA_01619	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HFBFALPA_01620	1.25e-241	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFBFALPA_01621	1.81e-29	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFBFALPA_01622	2.5e-59	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFBFALPA_01623	3.11e-141	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFBFALPA_01624	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HFBFALPA_01625	1.1e-206	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HFBFALPA_01626	3.69e-50	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HFBFALPA_01627	2.2e-68	-	-	-	-	-	-	-	-
HFBFALPA_01628	1.62e-63	-	-	-	-	-	-	-	-
HFBFALPA_01629	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HFBFALPA_01630	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFBFALPA_01631	4.19e-197	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HFBFALPA_01632	2.65e-246	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFBFALPA_01633	2.27e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HFBFALPA_01634	5.13e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HFBFALPA_01635	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HFBFALPA_01636	1.17e-78	-	-	-	S	-	-	-	GIY-YIG catalytic domain
HFBFALPA_01637	6.04e-203	-	-	-	V	-	-	-	ABC transporter transmembrane region
HFBFALPA_01639	2.63e-130	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HFBFALPA_01640	6.56e-43	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFBFALPA_01641	5.58e-91	-	-	-	S	-	-	-	Phage Mu protein F like protein
HFBFALPA_01642	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HFBFALPA_01644	2.29e-273	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFBFALPA_01645	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFBFALPA_01646	1.73e-218	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HFBFALPA_01647	4.43e-143	-	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_01648	4.62e-136	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HFBFALPA_01649	1.91e-124	-	-	-	-	-	-	-	-
HFBFALPA_01650	3.49e-48	-	-	-	-	-	-	-	-
HFBFALPA_01651	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
HFBFALPA_01652	6.25e-171	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HFBFALPA_01653	1.52e-237	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HFBFALPA_01654	1.46e-21	-	-	-	-	-	-	-	-
HFBFALPA_01655	1.76e-160	-	-	-	-	-	-	-	-
HFBFALPA_01656	2.44e-304	-	-	-	S	-	-	-	response to antibiotic
HFBFALPA_01657	5.48e-23	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFBFALPA_01658	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HFBFALPA_01659	5.02e-158	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HFBFALPA_01660	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFBFALPA_01661	8.97e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFBFALPA_01662	1.57e-141	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HFBFALPA_01663	1.06e-192	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HFBFALPA_01664	4.94e-103	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFBFALPA_01665	3.38e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFBFALPA_01666	5.55e-219	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HFBFALPA_01667	5.59e-134	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFBFALPA_01668	1.9e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBFALPA_01669	6.39e-69	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFBFALPA_01671	2.65e-123	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HFBFALPA_01672	2.83e-237	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HFBFALPA_01673	2.91e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HFBFALPA_01674	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
HFBFALPA_01675	5.09e-160	-	-	-	S	-	-	-	PAS domain
HFBFALPA_01676	3.9e-181	-	-	-	-	-	-	-	-
HFBFALPA_01677	1.91e-180	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HFBFALPA_01678	1.82e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HFBFALPA_01679	5.62e-138	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFBFALPA_01680	7.26e-203	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFBFALPA_01681	8.85e-217	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HFBFALPA_01682	5.95e-203	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HFBFALPA_01683	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFBFALPA_01684	4.47e-255	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFBFALPA_01685	1.15e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
HFBFALPA_01686	6.84e-188	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBFALPA_01687	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
HFBFALPA_01688	7.08e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBFALPA_01689	1.36e-214	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HFBFALPA_01690	4.96e-202	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HFBFALPA_01691	3.9e-125	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFBFALPA_01692	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HFBFALPA_01693	1.2e-207	-	-	-	-	-	-	-	-
HFBFALPA_01694	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFBFALPA_01695	9.35e-161	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HFBFALPA_01696	2.33e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFBFALPA_01697	4.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
HFBFALPA_01698	3.96e-126	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFBFALPA_01699	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFBFALPA_01700	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HFBFALPA_01701	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HFBFALPA_01702	8.34e-255	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFBFALPA_01703	2.52e-209	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFBFALPA_01704	4.5e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFBFALPA_01705	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HFBFALPA_01706	3.64e-237	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HFBFALPA_01707	1.58e-33	-	-	-	-	-	-	-	-
HFBFALPA_01708	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HFBFALPA_01709	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HFBFALPA_01711	2.79e-77	lysM	-	-	M	-	-	-	LysM domain
HFBFALPA_01712	8.23e-222	-	-	-	-	-	-	-	-
HFBFALPA_01713	3.23e-289	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HFBFALPA_01714	1.95e-69	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFBFALPA_01715	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFBFALPA_01716	1.56e-161	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFBFALPA_01717	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HFBFALPA_01718	3.13e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFBFALPA_01719	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFBFALPA_01720	1.63e-65	-	-	-	-	-	-	-	-
HFBFALPA_01721	1.24e-168	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HFBFALPA_01722	2.83e-115	dpnM	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	Site-specific DNA-methyltransferase (adenine-specific)
HFBFALPA_01724	3.89e-151	-	-	-	L	-	-	-	Integrase
HFBFALPA_01726	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HFBFALPA_01727	1.25e-119	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFBFALPA_01728	3.5e-77	-	-	-	S	-	-	-	Alpha beta hydrolase
HFBFALPA_01729	1.71e-26	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HFBFALPA_01730	3.33e-49	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HFBFALPA_01731	5.69e-185	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HFBFALPA_01732	5.21e-41	-	1.1.1.3	-	T	ko:K00003,ko:K07166	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoserine phosphatase activity
HFBFALPA_01733	2.02e-09	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HFBFALPA_01734	2.44e-134	-	-	-	K	ko:K09705	-	ko00000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFBFALPA_01735	1.3e-100	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFBFALPA_01736	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFBFALPA_01737	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HFBFALPA_01738	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFBFALPA_01739	2.25e-222	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFBFALPA_01740	1.28e-256	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HFBFALPA_01741	1.14e-277	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
HFBFALPA_01749	5.17e-30	-	-	-	-	-	-	-	-
HFBFALPA_01750	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFBFALPA_01751	1.33e-289	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HFBFALPA_01752	1.39e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HFBFALPA_01753	4.89e-159	-	-	-	S	-	-	-	membrane
HFBFALPA_01754	2.15e-101	-	-	-	K	-	-	-	LytTr DNA-binding domain
HFBFALPA_01755	4.32e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFBFALPA_01756	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HFBFALPA_01757	1.06e-37	-	-	-	S	-	-	-	Enterocin A Immunity
HFBFALPA_01758	1.73e-30	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFBFALPA_01759	7.56e-157	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFBFALPA_01760	3.01e-153	-	-	-	S	-	-	-	PAS domain
HFBFALPA_01761	2.37e-175	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HFBFALPA_01762	1.34e-261	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFBFALPA_01763	1.97e-140	pncA	-	-	Q	-	-	-	Isochorismatase family
HFBFALPA_01764	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFBFALPA_01765	2.58e-163	-	-	-	F	-	-	-	NUDIX domain
HFBFALPA_01766	1.37e-94	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HFBFALPA_01767	7.9e-28	-	-	-	-	-	-	-	-
HFBFALPA_01769	4.99e-123	-	-	-	L	-	-	-	reverse transcriptase
HFBFALPA_01770	1.34e-152	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFBFALPA_01771	1.7e-106	-	-	-	V	-	-	-	COG4823 Abortive infection bacteriophage resistance protein
HFBFALPA_01774	2.41e-27	-	-	-	-	-	-	-	-
HFBFALPA_01775	1.33e-30	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
HFBFALPA_01776	3.23e-138	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HFBFALPA_01777	2.41e-31	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HFBFALPA_01779	1.53e-102	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HFBFALPA_01780	1.78e-218	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HFBFALPA_01781	9.44e-169	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFBFALPA_01782	1.5e-150	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
HFBFALPA_01783	1.25e-128	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HFBFALPA_01784	2.77e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HFBFALPA_01785	1.13e-248	-	-	-	D	-	-	-	nuclear chromosome segregation
HFBFALPA_01786	8.58e-126	-	-	-	M	-	-	-	LysM domain protein
HFBFALPA_01787	5.26e-19	-	-	-	-	-	-	-	-
HFBFALPA_01788	4.15e-131	-	-	-	S	-	-	-	AAA ATPase domain
HFBFALPA_01789	1.02e-232	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFBFALPA_01790	9.2e-148	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HFBFALPA_01791	3.6e-209	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFBFALPA_01792	6.96e-269	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFBFALPA_01793	5.22e-276	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
HFBFALPA_01797	6.52e-34	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HFBFALPA_01798	6.97e-85	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HFBFALPA_01799	1.14e-111	-	-	-	-	-	-	-	-
HFBFALPA_01800	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFBFALPA_01801	1.09e-226	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HFBFALPA_01802	2.82e-185	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFBFALPA_01803	1.56e-181	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HFBFALPA_01804	1.07e-203	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HFBFALPA_01805	2.62e-164	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HFBFALPA_01806	3.43e-148	-	-	-	GM	-	-	-	NmrA-like family
HFBFALPA_01807	1.49e-71	-	-	-	-	-	-	-	-
HFBFALPA_01808	6.88e-231	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFBFALPA_01809	2.58e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFBFALPA_01810	3.27e-170	-	-	-	-	-	-	-	-
HFBFALPA_01811	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HFBFALPA_01812	5.22e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01813	2.12e-292	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HFBFALPA_01814	1.46e-264	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HFBFALPA_01815	6.11e-152	-	-	-	-	-	-	-	-
HFBFALPA_01816	3.81e-255	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HFBFALPA_01817	1.35e-167	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HFBFALPA_01818	5.96e-202	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HFBFALPA_01819	3.08e-43	-	-	-	-	-	-	-	-
HFBFALPA_01820	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HFBFALPA_01821	8.67e-111	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HFBFALPA_01822	1.26e-111	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HFBFALPA_01823	8.38e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFBFALPA_01824	3.78e-112	usp5	-	-	T	-	-	-	universal stress protein
HFBFALPA_01826	4.39e-198	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HFBFALPA_01827	2.82e-178	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HFBFALPA_01828	2.04e-164	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBFALPA_01829	4.13e-187	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFBFALPA_01830	7.09e-77	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HFBFALPA_01831	4.98e-107	-	-	-	-	-	-	-	-
HFBFALPA_01832	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HFBFALPA_01833	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFBFALPA_01834	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HFBFALPA_01836	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HFBFALPA_01837	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFBFALPA_01838	5.57e-129	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HFBFALPA_01839	8.61e-294	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HFBFALPA_01840	4.74e-286	yttB	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_01841	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFBFALPA_01844	3.68e-261	-	-	-	V	-	-	-	ABC transporter transmembrane region
HFBFALPA_01850	3.61e-13	sagB	-	-	C	-	-	-	coenzyme F420-1:gamma-L-glutamate ligase activity
HFBFALPA_01851	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HFBFALPA_01852	3.81e-151	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFBFALPA_01853	3.36e-230	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HFBFALPA_01854	9.84e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFBFALPA_01855	2.86e-143	-	-	-	G	-	-	-	phosphoglycerate mutase
HFBFALPA_01856	1.14e-179	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HFBFALPA_01857	6.89e-182	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HFBFALPA_01858	7.81e-155	-	-	-	-	-	-	-	-
HFBFALPA_01859	3.33e-63	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HFBFALPA_01860	4.65e-112	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HFBFALPA_01861	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFBFALPA_01864	1.16e-21	-	-	-	C	-	-	-	nitroreductase
HFBFALPA_01866	6.88e-34	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HFBFALPA_01867	2.32e-142	ackA	2.7.2.1	-	H	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFBFALPA_01868	1.23e-227	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HFBFALPA_01869	4.7e-191	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HFBFALPA_01870	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFBFALPA_01871	4.68e-193	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFBFALPA_01873	8.76e-80	-	-	-	L	-	-	-	RelB antitoxin
HFBFALPA_01875	3.71e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HFBFALPA_01876	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HFBFALPA_01878	1.43e-84	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HFBFALPA_01879	4.61e-118	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
HFBFALPA_01880	7.22e-133	-	-	-	L	-	-	-	HTH-like domain
HFBFALPA_01881	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HFBFALPA_01882	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFBFALPA_01883	2.37e-184	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HFBFALPA_01884	1.05e-112	-	-	-	-	-	-	-	-
HFBFALPA_01885	2.6e-96	-	-	-	-	-	-	-	-
HFBFALPA_01886	4.02e-204	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
HFBFALPA_01887	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFBFALPA_01888	2.46e-41	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_01889	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
HFBFALPA_01890	1.32e-34	-	-	-	-	-	-	-	-
HFBFALPA_01891	2.56e-186	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HFBFALPA_01892	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HFBFALPA_01893	1e-92	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFBFALPA_01894	2.06e-104	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HFBFALPA_01895	2.11e-249	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFBFALPA_01896	1.39e-96	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HFBFALPA_01897	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFBFALPA_01898	4.64e-53	-	-	-	S	-	-	-	Enterocin A Immunity
HFBFALPA_01899	3.58e-216	degS	2.7.13.3	-	F	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HFBFALPA_01900	1.52e-43	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HFBFALPA_01901	1.6e-41	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HFBFALPA_01902	2.43e-234	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFBFALPA_01903	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFBFALPA_01904	9.06e-60	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFBFALPA_01905	5.74e-142	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFBFALPA_01906	3.03e-187	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFBFALPA_01907	1.13e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFBFALPA_01908	1.09e-256	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HFBFALPA_01909	1.09e-169	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFBFALPA_01910	3.66e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFBFALPA_01911	1.75e-123	-	-	-	-	-	-	-	-
HFBFALPA_01912	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HFBFALPA_01913	6.09e-240	flp	-	-	V	-	-	-	Beta-lactamase
HFBFALPA_01914	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HFBFALPA_01915	1.59e-74	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFBFALPA_01916	6.8e-130	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HFBFALPA_01917	2.75e-09	-	-	-	-	-	-	-	-
HFBFALPA_01918	3.75e-122	tdh	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HFBFALPA_01919	1.53e-162	-	-	-	S	-	-	-	KR domain
HFBFALPA_01920	2.17e-138	-	-	-	C	-	-	-	nitroreductase
HFBFALPA_01921	7.47e-82	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HFBFALPA_01922	1.89e-91	-	-	-	GK	-	-	-	ROK family
HFBFALPA_01924	1.31e-78	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HFBFALPA_01925	7.31e-75	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HFBFALPA_01926	7.23e-22	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HFBFALPA_01927	3.52e-16	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFBFALPA_01928	3.88e-91	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFBFALPA_01929	7.5e-308	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFBFALPA_01930	3.23e-45	-	-	-	-	-	-	-	-
HFBFALPA_01931	8.26e-82	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01932	2.18e-236	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HFBFALPA_01933	8.9e-51	-	-	-	-	-	-	-	-
HFBFALPA_01934	5.43e-133	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HFBFALPA_01935	4.99e-10	-	-	-	-	-	-	-	-
HFBFALPA_01936	5.45e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFBFALPA_01937	2.85e-58	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFBFALPA_01938	1.74e-36	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFBFALPA_01939	1.29e-123	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HFBFALPA_01940	4.77e-258	-	-	-	-	-	-	-	-
HFBFALPA_01941	6.01e-265	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HFBFALPA_01942	3.9e-306	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HFBFALPA_01943	5.25e-39	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFBFALPA_01944	3.86e-73	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HFBFALPA_01945	2.03e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HFBFALPA_01946	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HFBFALPA_01947	1.34e-233	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFBFALPA_01948	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFBFALPA_01949	3.83e-227	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HFBFALPA_01950	2.02e-117	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
HFBFALPA_01951	5.2e-188	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFBFALPA_01954	4.11e-52	-	-	-	S	-	-	-	ThiS family
HFBFALPA_01955	2.36e-164	moeB	2.7.7.80, 2.8.1.11	-	H	ko:K21029,ko:K21147	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HFBFALPA_01956	4.8e-212	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HFBFALPA_01959	2.45e-205	-	-	-	D	-	-	-	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HFBFALPA_01961	5.83e-08	-	-	-	-	-	-	-	-
HFBFALPA_01962	9.73e-69	-	-	-	-	-	-	-	-
HFBFALPA_01963	8.48e-24	repA	-	-	S	-	-	-	Replication initiator protein A
HFBFALPA_01965	7.6e-139	-	-	-	L	-	-	-	Integrase
HFBFALPA_01966	8.96e-122	-	-	-	-	-	-	-	-
HFBFALPA_01967	1.18e-147	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HFBFALPA_01968	5.22e-136	-	-	-	-	-	-	-	-
HFBFALPA_01969	5.05e-47	-	-	-	-	-	-	-	-
HFBFALPA_01970	6.56e-114	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HFBFALPA_01971	1.26e-24	-	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_01972	2.3e-57	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFBFALPA_01973	5.18e-109	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HFBFALPA_01974	4.34e-198	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HFBFALPA_01975	2.15e-48	-	-	-	S	-	-	-	Transglycosylase associated protein
HFBFALPA_01976	1.13e-71	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFBFALPA_01977	8.5e-35	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HFBFALPA_01978	1.92e-140	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
HFBFALPA_01979	2.73e-32	flaR	-	-	F	-	-	-	topology modulation protein
HFBFALPA_01980	3.71e-95	-	-	-	-	-	-	-	-
HFBFALPA_01981	2.25e-51	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HFBFALPA_01982	5.91e-151	-	-	-	L	-	-	-	Resolvase, N terminal domain
HFBFALPA_01983	0.0	-	-	-	L	-	-	-	Putative transposase DNA-binding domain
HFBFALPA_01984	2.43e-56	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HFBFALPA_01985	2.52e-166	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HFBFALPA_01986	1.33e-99	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_01987	5.43e-138	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFBFALPA_01988	2.84e-33	-	-	-	-	-	-	-	-
HFBFALPA_01989	1.14e-123	-	-	-	-	-	-	-	-
HFBFALPA_01990	1.35e-135	-	-	-	S	-	-	-	SLAP domain
HFBFALPA_01991	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFBFALPA_01992	3.54e-191	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HFBFALPA_01993	2.02e-52	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HFBFALPA_01994	5.26e-38	-	-	-	-	-	-	-	-
HFBFALPA_01995	8.78e-155	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HFBFALPA_01996	4.65e-168	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system ATPase component
HFBFALPA_01999	8.74e-195	-	-	-	C	-	-	-	Nitroreductase
HFBFALPA_02000	1.64e-237	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HFBFALPA_02001	3.85e-34	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HFBFALPA_02002	7e-114	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
HFBFALPA_02004	1.48e-194	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type cobalt transport system permease component CbiQ and related transporters
HFBFALPA_02005	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFBFALPA_02006	1.23e-162	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF-type riboflavin transporter, S component
HFBFALPA_02007	1.54e-62	-	-	-	U	-	-	-	FFAT motif binding
HFBFALPA_02008	9.76e-104	-	-	-	U	-	-	-	FFAT motif binding
HFBFALPA_02009	7.17e-43	-	-	-	M	-	-	-	Rib/alpha-like repeat
HFBFALPA_02010	7.82e-211	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFBFALPA_02012	4.67e-105	-	-	-	M	-	-	-	domain protein
HFBFALPA_02013	0.0	-	-	-	S	ko:K21449	-	ko00000,ko02000	Domain of unknown function (DUF4430)
HFBFALPA_02014	2.49e-234	-	-	-	U	-	-	-	FFAT motif binding
HFBFALPA_02015	1.33e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HFBFALPA_02016	4.2e-24	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HFBFALPA_02017	1.21e-179	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HFBFALPA_02018	3.8e-21	-	-	-	S	-	-	-	Bacteriocin helveticin-J
HFBFALPA_02019	2.51e-203	-	-	-	-	-	-	-	-
HFBFALPA_02020	1.25e-97	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFBFALPA_02021	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HFBFALPA_02022	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFBFALPA_02023	4.13e-313	qacA	-	-	EGP	-	-	-	Major Facilitator
HFBFALPA_02028	1.04e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFBFALPA_02031	6.5e-38	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HFBFALPA_02033	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFBFALPA_02034	3.51e-308	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HFBFALPA_02035	3.03e-60	-	-	-	-	-	-	-	-
HFBFALPA_02036	4.23e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFBFALPA_02037	5.08e-143	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HFBFALPA_02038	2.65e-217	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HFBFALPA_02039	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFBFALPA_02040	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFBFALPA_02041	2.94e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFBFALPA_02042	2e-264	camS	-	-	S	-	-	-	sex pheromone
HFBFALPA_02043	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFBFALPA_02044	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HFBFALPA_02045	2.18e-138	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HFBFALPA_02047	1.06e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HFBFALPA_02048	4.89e-176	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HFBFALPA_02049	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HFBFALPA_02050	6.32e-288	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFBFALPA_02051	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HFBFALPA_02052	3.85e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFBFALPA_02053	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFBFALPA_02054	5.87e-256	-	-	-	M	-	-	-	Glycosyl transferases group 1
HFBFALPA_02055	8.02e-171	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFBFALPA_02056	3.33e-84	-	-	-	S	-	-	-	CAAX protease self-immunity
HFBFALPA_02057	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HFBFALPA_02058	7.77e-36	-	-	-	-	-	-	-	-
HFBFALPA_02059	1.13e-21	-	-	-	-	-	-	-	-
HFBFALPA_02060	8.68e-44	-	-	-	-	-	-	-	-
HFBFALPA_02061	8.68e-46	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HFBFALPA_02062	1.95e-45	-	-	-	S	-	-	-	Enterocin A Immunity
HFBFALPA_02063	1.76e-102	-	-	-	-	-	-	-	-
HFBFALPA_02064	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HFBFALPA_02065	2.54e-214	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HFBFALPA_02066	1.4e-179	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HFBFALPA_02069	5.26e-173	-	-	-	-	-	-	-	-
HFBFALPA_02070	4.04e-265	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFBFALPA_02071	4.75e-132	-	-	-	-	-	-	-	-
HFBFALPA_02072	7.34e-72	-	-	-	S	-	-	-	Fic/DOC family
HFBFALPA_02073	6.21e-53	-	-	-	S	-	-	-	Fic/DOC family
HFBFALPA_02074	3.29e-87	-	-	-	-	-	-	-	-
HFBFALPA_02075	2.89e-75	-	-	-	-	-	-	-	-
HFBFALPA_02076	5.55e-69	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HFBFALPA_02077	2.49e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFBFALPA_02078	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFBFALPA_02079	6.1e-213	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HFBFALPA_02080	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HFBFALPA_02081	1.11e-51	-	-	-	-	-	-	-	-
HFBFALPA_02082	5.41e-123	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
HFBFALPA_02083	6.05e-121	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
HFBFALPA_02084	2.54e-38	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
HFBFALPA_02085	1.4e-108	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HFBFALPA_02086	5.26e-63	-	-	-	K	-	-	-	Helix-turn-helix
HFBFALPA_02087	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HFBFALPA_02088	3.41e-80	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HFBFALPA_02089	1.49e-157	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
HFBFALPA_02090	2.37e-271	-	-	-	-	-	-	-	-
HFBFALPA_02093	2.88e-119	-	-	-	-	-	-	-	-
HFBFALPA_02094	6.39e-90	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HFBFALPA_02095	7.9e-287	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HFBFALPA_02097	1.06e-136	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
HFBFALPA_02098	6.8e-39	-	-	-	-	-	-	-	-
HFBFALPA_02099	4.75e-167	-	-	-	-	-	-	-	-
HFBFALPA_02100	3.86e-108	-	-	-	-	-	-	-	-
HFBFALPA_02101	0.0	-	-	-	-	-	-	-	-
HFBFALPA_02102	0.0	-	-	-	S	-	-	-	PglZ domain
HFBFALPA_02104	2.36e-68	-	-	-	LO	-	-	-	Belongs to the peptidase S16 family
HFBFALPA_02105	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
HFBFALPA_02106	4.02e-255	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HFBFALPA_02107	8.2e-145	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HFBFALPA_02108	7.8e-135	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HFBFALPA_02109	3.41e-294	-	-	-	S	-	-	-	Protein of unknown function DUF262
HFBFALPA_02110	1.56e-39	-	-	-	-	-	-	-	-
HFBFALPA_02111	1.55e-16	-	-	-	-	-	-	-	-
HFBFALPA_02112	1.72e-69	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFBFALPA_02113	1.39e-141	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HFBFALPA_02114	5.57e-117	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HFBFALPA_02115	1.35e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
HFBFALPA_02116	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
HFBFALPA_02117	7.15e-55	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HFBFALPA_02118	2.43e-30	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HFBFALPA_02119	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HFBFALPA_02120	2.4e-89	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HFBFALPA_02121	5.36e-219	yobV3	-	-	K	-	-	-	WYL domain
HFBFALPA_02122	2.33e-103	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HFBFALPA_02123	2.1e-44	-	-	-	-	-	-	-	-
HFBFALPA_02124	1.36e-71	-	-	-	-	-	-	-	-
HFBFALPA_02125	4.22e-71	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
HFBFALPA_02126	9.99e-86	-	-	-	S	-	-	-	ASCH domain
HFBFALPA_02127	1.05e-142	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFBFALPA_02128	5.82e-105	-	-	-	-	-	-	-	-
HFBFALPA_02129	0.0	-	-	-	-	-	-	-	-
HFBFALPA_02130	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HFBFALPA_02131	1.01e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HFBFALPA_02132	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system