ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MDLMDKEJ_00001 3.53e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MDLMDKEJ_00002 3.03e-187 - - - S - - - haloacid dehalogenase-like hydrolase
MDLMDKEJ_00003 6.91e-165 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MDLMDKEJ_00004 1.63e-152 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
MDLMDKEJ_00005 1.19e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDLMDKEJ_00006 1.25e-204 - - - S - - - Aldo/keto reductase family
MDLMDKEJ_00007 4.74e-217 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDLMDKEJ_00008 9.19e-266 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDLMDKEJ_00009 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MDLMDKEJ_00010 9.41e-257 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MDLMDKEJ_00011 1.21e-236 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
MDLMDKEJ_00012 4.51e-134 - - - S - - - ECF transporter, substrate-specific component
MDLMDKEJ_00013 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_00014 3.39e-253 - - - S - - - DUF218 domain
MDLMDKEJ_00015 2.41e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDLMDKEJ_00016 1.4e-88 - - - K - - - Helix-turn-helix XRE-family like proteins
MDLMDKEJ_00017 5.7e-125 - - - M - - - CHAP domain
MDLMDKEJ_00018 1.57e-197 mutR - - K - - - Helix-turn-helix XRE-family like proteins
MDLMDKEJ_00019 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MDLMDKEJ_00020 2.82e-105 - - - S - - - Putative adhesin
MDLMDKEJ_00021 4.69e-262 napA - - P - - - Sodium/hydrogen exchanger family
MDLMDKEJ_00022 0.0 cadA - - P - - - P-type ATPase
MDLMDKEJ_00023 1.97e-107 ykuL - - S - - - (CBS) domain
MDLMDKEJ_00024 8.03e-278 - - - S - - - Membrane
MDLMDKEJ_00025 2.18e-53 - - - - - - - -
MDLMDKEJ_00026 2.17e-25 - - - S - - - D-Ala-teichoic acid biosynthesis protein
MDLMDKEJ_00027 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDLMDKEJ_00028 3.35e-310 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MDLMDKEJ_00029 2.46e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDLMDKEJ_00030 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDLMDKEJ_00031 3.4e-228 pbpX2 - - V - - - Beta-lactamase
MDLMDKEJ_00032 2.86e-81 - - - - - - - -
MDLMDKEJ_00033 9.09e-164 - - - S - - - Protein of unknown function (DUF975)
MDLMDKEJ_00034 9.26e-222 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDLMDKEJ_00035 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MDLMDKEJ_00036 5.63e-49 - - - - - - - -
MDLMDKEJ_00037 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_00038 8.01e-162 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_00039 1e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_00040 4.24e-217 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MDLMDKEJ_00041 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
MDLMDKEJ_00042 1.07e-150 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MDLMDKEJ_00043 1.33e-75 - - - - - - - -
MDLMDKEJ_00044 1.02e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
MDLMDKEJ_00045 1.07e-163 - - - S - - - Alpha/beta hydrolase family
MDLMDKEJ_00046 2.63e-204 - - - M - - - Glycosyltransferase like family 2
MDLMDKEJ_00047 5.06e-182 - - - S - - - Protein of unknown function (DUF1002)
MDLMDKEJ_00048 2.82e-183 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDLMDKEJ_00049 1.45e-231 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MDLMDKEJ_00050 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDLMDKEJ_00051 9.36e-111 - - - - - - - -
MDLMDKEJ_00052 2.57e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
MDLMDKEJ_00053 9.33e-180 terC - - P - - - Integral membrane protein TerC family
MDLMDKEJ_00054 2.29e-85 yeaO - - S - - - Protein of unknown function, DUF488
MDLMDKEJ_00055 3.08e-159 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MDLMDKEJ_00056 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_00057 2.21e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_00058 1.63e-233 yhaH - - S - - - Protein of unknown function (DUF805)
MDLMDKEJ_00059 2.73e-206 - - - L - - - HNH nucleases
MDLMDKEJ_00060 1.07e-157 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MDLMDKEJ_00061 2.11e-271 - - - G - - - Glycosyl hydrolases family 8
MDLMDKEJ_00062 1.08e-288 ydaM - - M - - - Glycosyl transferase family group 2
MDLMDKEJ_00064 2.14e-197 - - - - - - - -
MDLMDKEJ_00065 9.69e-25 - - - - - - - -
MDLMDKEJ_00066 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
MDLMDKEJ_00067 7.83e-91 - - - S - - - Iron-sulphur cluster biosynthesis
MDLMDKEJ_00068 3.36e-249 ysdE - - P - - - Citrate transporter
MDLMDKEJ_00069 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
MDLMDKEJ_00070 9.9e-209 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
MDLMDKEJ_00071 2.11e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
MDLMDKEJ_00072 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_00073 6.92e-130 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
MDLMDKEJ_00074 8e-226 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MDLMDKEJ_00075 1.09e-157 - - - - - - - -
MDLMDKEJ_00076 1.98e-26 - - - - - - - -
MDLMDKEJ_00077 0.0 - - - S - - - CAAX protease self-immunity
MDLMDKEJ_00079 1.51e-194 - - - K - - - Helix-turn-helix XRE-family like proteins
MDLMDKEJ_00080 2.48e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDLMDKEJ_00081 2.7e-257 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MDLMDKEJ_00082 9.1e-193 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MDLMDKEJ_00083 2.91e-189 yycI - - S - - - YycH protein
MDLMDKEJ_00084 0.0 yycH - - S - - - YycH protein
MDLMDKEJ_00085 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDLMDKEJ_00086 9.77e-170 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MDLMDKEJ_00089 8.71e-157 - - - - - - - -
MDLMDKEJ_00090 4.27e-293 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MDLMDKEJ_00091 1.84e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
MDLMDKEJ_00092 1.4e-180 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MDLMDKEJ_00093 1e-305 - - - E - - - amino acid
MDLMDKEJ_00094 1.27e-70 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
MDLMDKEJ_00095 1.75e-10 - - - - - - - -
MDLMDKEJ_00096 6.09e-152 - - - K - - - Rhodanese Homology Domain
MDLMDKEJ_00097 1.23e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDLMDKEJ_00098 6.65e-153 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
MDLMDKEJ_00099 4.6e-249 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
MDLMDKEJ_00100 1.69e-259 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MDLMDKEJ_00103 2.84e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDLMDKEJ_00104 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDLMDKEJ_00105 1.14e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDLMDKEJ_00106 6.33e-74 - - - - - - - -
MDLMDKEJ_00107 7.08e-137 - - - - - - - -
MDLMDKEJ_00108 1.41e-209 yicL - - EG - - - EamA-like transporter family
MDLMDKEJ_00109 1.03e-211 - - - EG - - - EamA-like transporter family
MDLMDKEJ_00110 8.16e-212 - - - EG - - - EamA-like transporter family
MDLMDKEJ_00111 1.96e-108 - - - M - - - NlpC/P60 family
MDLMDKEJ_00112 1.91e-171 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MDLMDKEJ_00113 9.67e-220 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
MDLMDKEJ_00114 1.23e-83 - - - S - - - Protein conserved in bacteria
MDLMDKEJ_00115 6.65e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MDLMDKEJ_00116 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDLMDKEJ_00117 1.06e-20 - - - - - - - -
MDLMDKEJ_00118 4.8e-99 - - - - - - - -
MDLMDKEJ_00119 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MDLMDKEJ_00120 7.79e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MDLMDKEJ_00121 7.43e-229 yvdE - - K - - - helix_turn _helix lactose operon repressor
MDLMDKEJ_00122 1.82e-276 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDLMDKEJ_00123 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MDLMDKEJ_00124 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MDLMDKEJ_00125 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MDLMDKEJ_00126 1.23e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
MDLMDKEJ_00143 1.98e-96 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MDLMDKEJ_00144 0.0 - - - L - - - Helicase C-terminal domain protein
MDLMDKEJ_00145 3.83e-61 - - - L - - - Helicase C-terminal domain protein
MDLMDKEJ_00157 2.24e-284 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
MDLMDKEJ_00158 1.5e-255 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MDLMDKEJ_00159 5.18e-228 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDLMDKEJ_00160 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDLMDKEJ_00161 5.29e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MDLMDKEJ_00162 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDLMDKEJ_00163 1.99e-99 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDLMDKEJ_00164 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDLMDKEJ_00165 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
MDLMDKEJ_00166 8.36e-102 - - - - - - - -
MDLMDKEJ_00167 1.11e-191 - - - I - - - Acyl-transferase
MDLMDKEJ_00168 6.45e-204 arbx - - M - - - Glycosyl transferase family 8
MDLMDKEJ_00169 1.07e-238 - - - M - - - Glycosyl transferase family 8
MDLMDKEJ_00170 1.34e-235 - - - M - - - Glycosyl transferase family 8
MDLMDKEJ_00171 2.27e-214 arbZ - - I - - - Phosphate acyltransferases
MDLMDKEJ_00172 2.5e-51 - - - S - - - Cytochrome B5
MDLMDKEJ_00173 3.17e-149 - - - K - - - Transcriptional regulator, LysR family
MDLMDKEJ_00174 1.87e-292 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MDLMDKEJ_00175 4.38e-74 - - - S - - - FMN_bind
MDLMDKEJ_00176 3.73e-65 - - - K - - - LysR substrate binding domain
MDLMDKEJ_00178 1.46e-240 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MDLMDKEJ_00179 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
MDLMDKEJ_00180 8.15e-242 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
MDLMDKEJ_00181 1.79e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MDLMDKEJ_00182 0.0 - - - S - - - Domain of unknown function (DUF5060)
MDLMDKEJ_00183 1.05e-274 - - - EGP - - - Transporter, major facilitator family protein
MDLMDKEJ_00184 2.88e-223 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDLMDKEJ_00185 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain
MDLMDKEJ_00186 2e-79 - - - G - - - polysaccharide catabolic process
MDLMDKEJ_00187 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDLMDKEJ_00188 1.28e-131 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDLMDKEJ_00189 1.47e-144 - - - S - - - SNARE associated Golgi protein
MDLMDKEJ_00190 1.84e-196 - - - I - - - alpha/beta hydrolase fold
MDLMDKEJ_00191 4.92e-207 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
MDLMDKEJ_00192 3.62e-121 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MDLMDKEJ_00193 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MDLMDKEJ_00194 3.27e-294 - - - E ko:K03294 - ko00000 amino acid
MDLMDKEJ_00195 9.79e-168 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDLMDKEJ_00196 2.35e-269 yfmL - - L - - - DEAD DEAH box helicase
MDLMDKEJ_00197 5.88e-312 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_00200 4.67e-116 gtcA1 - - S - - - Teichoic acid glycosylation protein
MDLMDKEJ_00201 8.53e-104 ykuP - - C ko:K03839 - ko00000 Flavodoxin
MDLMDKEJ_00202 7.02e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MDLMDKEJ_00203 1.14e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MDLMDKEJ_00204 6.78e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MDLMDKEJ_00205 3.81e-275 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MDLMDKEJ_00206 3.42e-278 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MDLMDKEJ_00207 3.82e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MDLMDKEJ_00208 2.95e-61 - - - - - - - -
MDLMDKEJ_00209 2.13e-227 ybcH - - D ko:K06889 - ko00000 Alpha beta
MDLMDKEJ_00210 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDLMDKEJ_00211 4.13e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MDLMDKEJ_00212 7.42e-112 - - - - - - - -
MDLMDKEJ_00213 1.02e-93 - - - - - - - -
MDLMDKEJ_00214 1.24e-201 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MDLMDKEJ_00215 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDLMDKEJ_00216 3.43e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MDLMDKEJ_00217 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
MDLMDKEJ_00218 9.05e-55 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MDLMDKEJ_00219 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDLMDKEJ_00220 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDLMDKEJ_00221 2.91e-175 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDLMDKEJ_00222 2.56e-209 coiA - - S ko:K06198 - ko00000 Competence protein
MDLMDKEJ_00223 7.54e-149 yjbH - - Q - - - Thioredoxin
MDLMDKEJ_00224 1.46e-145 - - - S - - - CYTH
MDLMDKEJ_00225 1.15e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MDLMDKEJ_00226 5.49e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDLMDKEJ_00227 1.81e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MDLMDKEJ_00228 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MDLMDKEJ_00229 8.93e-153 - - - S - - - SNARE associated Golgi protein
MDLMDKEJ_00230 1.06e-257 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MDLMDKEJ_00231 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
MDLMDKEJ_00232 8.1e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MDLMDKEJ_00233 8.9e-270 XK27_05220 - - S - - - AI-2E family transporter
MDLMDKEJ_00234 1.75e-134 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDLMDKEJ_00235 1.28e-89 - - - S - - - Protein of unknown function (DUF1149)
MDLMDKEJ_00236 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MDLMDKEJ_00237 4.09e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
MDLMDKEJ_00238 2.26e-306 ymfH - - S - - - Peptidase M16
MDLMDKEJ_00239 8.02e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MDLMDKEJ_00240 1.43e-160 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MDLMDKEJ_00241 1.73e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDLMDKEJ_00242 6.24e-247 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDLMDKEJ_00243 1.29e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MDLMDKEJ_00244 3.37e-271 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
MDLMDKEJ_00245 2.05e-153 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MDLMDKEJ_00246 8.33e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MDLMDKEJ_00247 7.21e-173 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MDLMDKEJ_00248 1.75e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDLMDKEJ_00249 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDLMDKEJ_00250 6.43e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDLMDKEJ_00251 1.88e-21 - - - - - - - -
MDLMDKEJ_00252 6.85e-228 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDLMDKEJ_00253 4.36e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDLMDKEJ_00254 1.71e-241 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MDLMDKEJ_00255 9.38e-228 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDLMDKEJ_00256 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MDLMDKEJ_00257 4.02e-284 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MDLMDKEJ_00258 5.82e-272 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MDLMDKEJ_00259 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MDLMDKEJ_00260 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MDLMDKEJ_00261 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MDLMDKEJ_00262 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDLMDKEJ_00263 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDLMDKEJ_00264 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDLMDKEJ_00265 3.8e-118 - - - S - - - Short repeat of unknown function (DUF308)
MDLMDKEJ_00266 6e-212 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MDLMDKEJ_00267 3.24e-250 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MDLMDKEJ_00268 1.17e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MDLMDKEJ_00269 2.16e-129 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDLMDKEJ_00270 0.0 - - - S - - - SH3-like domain
MDLMDKEJ_00271 0.0 ycaM - - E - - - amino acid
MDLMDKEJ_00273 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MDLMDKEJ_00274 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDLMDKEJ_00275 9.96e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MDLMDKEJ_00276 2.71e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDLMDKEJ_00277 1.07e-125 - - - - - - - -
MDLMDKEJ_00278 1.02e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDLMDKEJ_00279 1.15e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDLMDKEJ_00280 3.84e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MDLMDKEJ_00281 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MDLMDKEJ_00282 5.26e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MDLMDKEJ_00283 7.27e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MDLMDKEJ_00284 2.94e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDLMDKEJ_00285 1.04e-180 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_00286 2.65e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_00287 9.5e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_00288 1.06e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDLMDKEJ_00289 3.38e-221 ybbR - - S - - - YbbR-like protein
MDLMDKEJ_00290 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDLMDKEJ_00291 4.85e-191 - - - S - - - hydrolase
MDLMDKEJ_00292 1.45e-187 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MDLMDKEJ_00293 7.3e-156 - - - - - - - -
MDLMDKEJ_00294 2.73e-111 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDLMDKEJ_00295 1.37e-269 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
MDLMDKEJ_00296 4.66e-196 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MDLMDKEJ_00297 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDLMDKEJ_00298 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_00299 6.14e-232 ybcH - - D ko:K06889 - ko00000 Alpha beta
MDLMDKEJ_00300 0.0 - - - E - - - Amino acid permease
MDLMDKEJ_00302 1.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDLMDKEJ_00303 2.34e-119 - - - S - - - VanZ like family
MDLMDKEJ_00304 1.97e-171 yebC - - K - - - Transcriptional regulatory protein
MDLMDKEJ_00305 1.38e-228 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MDLMDKEJ_00306 5.57e-224 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MDLMDKEJ_00307 1.55e-65 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
MDLMDKEJ_00308 9e-94 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
MDLMDKEJ_00309 1.33e-25 - - - - - - - -
MDLMDKEJ_00310 2.61e-120 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
MDLMDKEJ_00311 4.19e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MDLMDKEJ_00312 1.35e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDLMDKEJ_00314 1.05e-170 - - - M - - - Protein of unknown function (DUF3737)
MDLMDKEJ_00315 3.52e-224 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MDLMDKEJ_00316 4.53e-41 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MDLMDKEJ_00317 1.86e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MDLMDKEJ_00318 1.68e-81 - - - S - - - SdpI/YhfL protein family
MDLMDKEJ_00319 1.97e-170 - - - K - - - Transcriptional regulatory protein, C terminal
MDLMDKEJ_00320 0.0 yclK - - T - - - Histidine kinase
MDLMDKEJ_00321 4.37e-81 XK27_00915 - - C - - - Luciferase-like monooxygenase
MDLMDKEJ_00322 1.53e-159 XK27_00915 - - C - - - Luciferase-like monooxygenase
MDLMDKEJ_00323 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDLMDKEJ_00324 1.93e-139 vanZ - - V - - - VanZ like family
MDLMDKEJ_00325 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MDLMDKEJ_00326 5.4e-316 - - - EGP - - - Major Facilitator
MDLMDKEJ_00327 7.36e-251 ampC - - V - - - Beta-lactamase
MDLMDKEJ_00330 2.17e-85 - - - - - - - -
MDLMDKEJ_00331 0.0 - - - S ko:K06919 - ko00000 DNA primase
MDLMDKEJ_00332 1.18e-47 - - - - - - - -
MDLMDKEJ_00333 6.8e-46 - - - - - - - -
MDLMDKEJ_00334 3.84e-90 - - - - - - - -
MDLMDKEJ_00335 2.58e-49 - - - - - - - -
MDLMDKEJ_00337 3.5e-75 - - - K - - - Transcriptional
MDLMDKEJ_00338 1.58e-266 - - - L - - - Belongs to the 'phage' integrase family
MDLMDKEJ_00339 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MDLMDKEJ_00340 4.64e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MDLMDKEJ_00341 1.01e-235 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDLMDKEJ_00342 2.52e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDLMDKEJ_00343 4.93e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDLMDKEJ_00344 1.84e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDLMDKEJ_00345 4.13e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MDLMDKEJ_00346 4.36e-39 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDLMDKEJ_00347 4.97e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDLMDKEJ_00348 6.82e-122 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDLMDKEJ_00349 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDLMDKEJ_00350 1.22e-220 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDLMDKEJ_00351 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDLMDKEJ_00352 7.03e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MDLMDKEJ_00353 4.22e-41 - - - S - - - Protein of unknown function (DUF1146)
MDLMDKEJ_00354 2.04e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MDLMDKEJ_00355 7.58e-67 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MDLMDKEJ_00356 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
MDLMDKEJ_00357 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MDLMDKEJ_00358 6.39e-102 uspA - - T - - - universal stress protein
MDLMDKEJ_00359 1.41e-49 - - - - - - - -
MDLMDKEJ_00360 1.18e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MDLMDKEJ_00361 9.44e-109 - - - S - - - Protein of unknown function (DUF1694)
MDLMDKEJ_00362 1.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDLMDKEJ_00363 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDLMDKEJ_00364 1.29e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MDLMDKEJ_00365 4.62e-293 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDLMDKEJ_00366 1.56e-165 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MDLMDKEJ_00367 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDLMDKEJ_00368 2.55e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MDLMDKEJ_00369 1.83e-163 - - - S - - - Haloacid dehalogenase-like hydrolase
MDLMDKEJ_00370 2.34e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
MDLMDKEJ_00371 2.03e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MDLMDKEJ_00372 1.82e-192 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MDLMDKEJ_00373 6.61e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
MDLMDKEJ_00374 1.45e-14 - - - S - - - Protein of unknown function (DUF4044)
MDLMDKEJ_00375 4.84e-71 - - - S - - - Protein of unknown function (DUF3397)
MDLMDKEJ_00376 3.95e-93 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MDLMDKEJ_00377 5.41e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDLMDKEJ_00378 1.32e-71 ftsL - - D - - - Cell division protein FtsL
MDLMDKEJ_00379 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MDLMDKEJ_00380 8e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDLMDKEJ_00381 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDLMDKEJ_00382 4.93e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDLMDKEJ_00383 1.71e-182 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDLMDKEJ_00384 1.02e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDLMDKEJ_00385 5.9e-313 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDLMDKEJ_00386 4.09e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDLMDKEJ_00387 1.36e-39 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
MDLMDKEJ_00388 4.87e-193 ylmH - - S - - - S4 domain protein
MDLMDKEJ_00389 1.18e-141 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
MDLMDKEJ_00390 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDLMDKEJ_00391 8.09e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MDLMDKEJ_00392 6.29e-135 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MDLMDKEJ_00393 4.49e-42 - - - - - - - -
MDLMDKEJ_00394 1.02e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDLMDKEJ_00395 1.47e-76 XK27_04120 - - S - - - Putative amino acid metabolism
MDLMDKEJ_00396 1.62e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDLMDKEJ_00397 1.58e-161 pgm - - G - - - Phosphoglycerate mutase family
MDLMDKEJ_00398 2.93e-150 - - - S - - - repeat protein
MDLMDKEJ_00399 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDLMDKEJ_00400 0.0 - - - L - - - Nuclease-related domain
MDLMDKEJ_00401 1.29e-233 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MDLMDKEJ_00402 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDLMDKEJ_00403 3.13e-46 ykzG - - S - - - Belongs to the UPF0356 family
MDLMDKEJ_00404 2.52e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDLMDKEJ_00405 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MDLMDKEJ_00406 2.75e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MDLMDKEJ_00407 4.73e-69 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MDLMDKEJ_00408 5.62e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MDLMDKEJ_00409 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDLMDKEJ_00410 1.37e-246 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MDLMDKEJ_00411 2.19e-131 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MDLMDKEJ_00412 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MDLMDKEJ_00413 3.38e-227 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MDLMDKEJ_00414 3.78e-48 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MDLMDKEJ_00415 4.08e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDLMDKEJ_00416 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDLMDKEJ_00417 1.45e-195 - - - - - - - -
MDLMDKEJ_00418 8.19e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDLMDKEJ_00419 3.02e-294 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDLMDKEJ_00420 8.42e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDLMDKEJ_00421 1.17e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MDLMDKEJ_00422 7.3e-245 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDLMDKEJ_00423 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MDLMDKEJ_00424 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDLMDKEJ_00425 1.39e-106 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDLMDKEJ_00426 5.48e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDLMDKEJ_00427 1.14e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDLMDKEJ_00428 1.23e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDLMDKEJ_00429 2.42e-281 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MDLMDKEJ_00430 4.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDLMDKEJ_00431 8.12e-262 pbpX1 - - V - - - Beta-lactamase
MDLMDKEJ_00432 0.0 - - - I - - - Protein of unknown function (DUF2974)
MDLMDKEJ_00433 1.18e-55 - - - C - - - FMN_bind
MDLMDKEJ_00434 1.01e-104 - - - - - - - -
MDLMDKEJ_00435 0.0 - - - - - - - -
MDLMDKEJ_00436 4.65e-228 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
MDLMDKEJ_00437 8.04e-188 - - - - - - - -
MDLMDKEJ_00441 4.23e-93 alkD - - L - - - DNA alkylation repair enzyme
MDLMDKEJ_00442 3.08e-52 - - - S - - - Transglycosylase associated protein
MDLMDKEJ_00443 6.28e-10 - - - S - - - CsbD-like
MDLMDKEJ_00444 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_00445 1.62e-166 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
MDLMDKEJ_00446 4.98e-74 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MDLMDKEJ_00447 4.75e-80 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MDLMDKEJ_00448 4.68e-104 - - - - - - - -
MDLMDKEJ_00449 1.68e-179 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_00450 2.84e-94 - - - S - - - Domain of unknown function (DUF3284)
MDLMDKEJ_00451 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_00452 1.45e-172 - - - K ko:K03492 - ko00000,ko03000 UTRA
MDLMDKEJ_00453 1.91e-55 - - - - - - - -
MDLMDKEJ_00454 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_00455 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_00456 3.69e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MDLMDKEJ_00457 1.01e-111 yfhC - - C - - - Nitroreductase family
MDLMDKEJ_00458 4.93e-141 - - - S - - - Domain of unknown function (DUF4767)
MDLMDKEJ_00459 2.12e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDLMDKEJ_00460 1.19e-194 - - - S - - - Uncharacterised protein, DegV family COG1307
MDLMDKEJ_00461 2.64e-128 - - - I - - - PAP2 superfamily
MDLMDKEJ_00462 1.47e-244 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDLMDKEJ_00464 2.59e-229 int3 - - L - - - Belongs to the 'phage' integrase family
MDLMDKEJ_00465 1.09e-34 - - - - - - - -
MDLMDKEJ_00466 1.98e-129 - - - - - - - -
MDLMDKEJ_00467 0.000281 - - - - - - - -
MDLMDKEJ_00468 9.27e-75 - - - K - - - Cro/C1-type HTH DNA-binding domain
MDLMDKEJ_00469 2.16e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
MDLMDKEJ_00470 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
MDLMDKEJ_00471 1.21e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDLMDKEJ_00472 1.53e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDLMDKEJ_00473 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MDLMDKEJ_00474 1.03e-203 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MDLMDKEJ_00475 2.07e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDLMDKEJ_00476 4.45e-127 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_00477 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDLMDKEJ_00478 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
MDLMDKEJ_00479 0.0 - - - M - - - domain protein
MDLMDKEJ_00480 5.14e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MDLMDKEJ_00481 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MDLMDKEJ_00482 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
MDLMDKEJ_00483 7.54e-200 - - - I - - - Alpha/beta hydrolase family
MDLMDKEJ_00484 4.25e-248 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MDLMDKEJ_00485 2.76e-60 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MDLMDKEJ_00486 6.24e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MDLMDKEJ_00487 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MDLMDKEJ_00489 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
MDLMDKEJ_00490 6.03e-19 - - - - - - - -
MDLMDKEJ_00491 1.14e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MDLMDKEJ_00492 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_00493 4.42e-124 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MDLMDKEJ_00494 2.09e-83 - - - S - - - Domain of unknown function DUF1828
MDLMDKEJ_00495 5.21e-71 - - - - - - - -
MDLMDKEJ_00496 1.56e-228 citR - - K - - - Putative sugar-binding domain
MDLMDKEJ_00497 3.82e-312 - - - S - - - Putative threonine/serine exporter
MDLMDKEJ_00498 7.54e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDLMDKEJ_00499 1.32e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MDLMDKEJ_00500 1.17e-65 - - - - - - - -
MDLMDKEJ_00501 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDLMDKEJ_00502 2.56e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDLMDKEJ_00503 1.74e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MDLMDKEJ_00504 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDLMDKEJ_00505 9.94e-287 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MDLMDKEJ_00506 1.03e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDLMDKEJ_00507 2.72e-197 - - - S - - - reductase
MDLMDKEJ_00508 3.29e-193 yxeH - - S - - - hydrolase
MDLMDKEJ_00509 2.31e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDLMDKEJ_00510 5.04e-298 yhdG - - E ko:K03294 - ko00000 Amino Acid
MDLMDKEJ_00511 4.52e-140 yngC - - S - - - SNARE associated Golgi protein
MDLMDKEJ_00512 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDLMDKEJ_00513 3.01e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDLMDKEJ_00514 0.0 oatA - - I - - - Acyltransferase
MDLMDKEJ_00515 6.35e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDLMDKEJ_00516 1.5e-186 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
MDLMDKEJ_00517 2.25e-45 - - - S - - - Lipopolysaccharide assembly protein A domain
MDLMDKEJ_00518 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MDLMDKEJ_00519 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MDLMDKEJ_00520 3.9e-33 - - - S - - - Protein of unknown function (DUF2929)
MDLMDKEJ_00521 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MDLMDKEJ_00522 7.76e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MDLMDKEJ_00523 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MDLMDKEJ_00524 1e-216 yitL - - S ko:K00243 - ko00000 S1 domain
MDLMDKEJ_00525 2.19e-218 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MDLMDKEJ_00526 6.56e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDLMDKEJ_00527 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDLMDKEJ_00528 5.75e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDLMDKEJ_00529 3.66e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MDLMDKEJ_00530 6.79e-152 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDLMDKEJ_00531 7.33e-71 - - - M - - - Lysin motif
MDLMDKEJ_00532 1.28e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MDLMDKEJ_00533 4.07e-270 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MDLMDKEJ_00534 3.15e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MDLMDKEJ_00535 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDLMDKEJ_00536 2.22e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MDLMDKEJ_00537 1.3e-207 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDLMDKEJ_00538 8.15e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDLMDKEJ_00539 7.33e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MDLMDKEJ_00540 6.34e-193 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
MDLMDKEJ_00541 1.64e-47 yozE - - S - - - Belongs to the UPF0346 family
MDLMDKEJ_00542 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
MDLMDKEJ_00543 8.81e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDLMDKEJ_00544 8.96e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDLMDKEJ_00545 1.07e-201 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MDLMDKEJ_00546 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDLMDKEJ_00547 2.09e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MDLMDKEJ_00548 2.27e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
MDLMDKEJ_00549 3.29e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MDLMDKEJ_00550 4.61e-308 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MDLMDKEJ_00551 7.16e-232 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MDLMDKEJ_00552 1.72e-85 - - - - - - - -
MDLMDKEJ_00553 4.82e-296 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_00554 1.25e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MDLMDKEJ_00555 2.82e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
MDLMDKEJ_00556 7.42e-89 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDLMDKEJ_00557 9.18e-83 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDLMDKEJ_00558 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MDLMDKEJ_00559 0.0 - - - E - - - Amino acid permease
MDLMDKEJ_00560 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MDLMDKEJ_00561 1.13e-312 ynbB - - P - - - aluminum resistance
MDLMDKEJ_00562 6.35e-154 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
MDLMDKEJ_00563 7.3e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
MDLMDKEJ_00564 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MDLMDKEJ_00565 1.47e-105 - - - C - - - Flavodoxin
MDLMDKEJ_00566 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
MDLMDKEJ_00567 4.33e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
MDLMDKEJ_00568 8.43e-148 - - - I - - - Acid phosphatase homologues
MDLMDKEJ_00569 5.22e-89 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDLMDKEJ_00570 1.71e-265 - - - V - - - Beta-lactamase
MDLMDKEJ_00571 2.42e-201 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MDLMDKEJ_00572 2.46e-121 - - - S - - - ECF-type riboflavin transporter, S component
MDLMDKEJ_00573 1.84e-281 - - - S - - - Putative peptidoglycan binding domain
MDLMDKEJ_00574 5.05e-313 - - - - - - - -
MDLMDKEJ_00575 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDLMDKEJ_00576 2.78e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MDLMDKEJ_00577 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MDLMDKEJ_00578 5.68e-165 - - - M - - - Glycosyl transferases group 1
MDLMDKEJ_00579 5.84e-129 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDLMDKEJ_00580 7.57e-211 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MDLMDKEJ_00581 2.61e-19 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDLMDKEJ_00582 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDLMDKEJ_00583 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDLMDKEJ_00584 9.5e-39 - - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MDLMDKEJ_00585 1.72e-208 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
MDLMDKEJ_00586 5.93e-149 - - - GM - - - NAD dependent epimerase dehydratase family protein
MDLMDKEJ_00587 5.96e-205 - - - K - - - Transcriptional regulator
MDLMDKEJ_00588 6.27e-215 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
MDLMDKEJ_00589 1.08e-212 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MDLMDKEJ_00590 1.31e-211 yvgN - - C - - - Aldo keto reductase
MDLMDKEJ_00591 5.42e-275 - - - S - - - SLAP domain
MDLMDKEJ_00592 1.7e-133 - - - K - - - Acetyltransferase (GNAT) domain
MDLMDKEJ_00595 2.77e-134 - - - - - - - -
MDLMDKEJ_00596 2.07e-102 - - - K - - - Transcriptional regulator
MDLMDKEJ_00597 8.07e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MDLMDKEJ_00598 3.34e-211 - - - S - - - reductase
MDLMDKEJ_00599 2.77e-220 - - - - - - - -
MDLMDKEJ_00600 4.2e-42 lysR - - K - - - Transcriptional regulator
MDLMDKEJ_00601 3.25e-145 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
MDLMDKEJ_00602 2.48e-131 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_00603 6.13e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_00604 3.59e-205 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MDLMDKEJ_00605 2.66e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDLMDKEJ_00606 1.72e-142 - - - G - - - Phosphoglycerate mutase family
MDLMDKEJ_00607 1.81e-223 - - - S ko:K07045 - ko00000 Amidohydrolase
MDLMDKEJ_00608 5.1e-43 - - - - - - - -
MDLMDKEJ_00609 1.41e-141 - - - - - - - -
MDLMDKEJ_00610 3.18e-140 - - - - - - - -
MDLMDKEJ_00611 3.18e-167 - - - F - - - glutamine amidotransferase
MDLMDKEJ_00612 9.73e-275 - - - EGP - - - Major Facilitator Superfamily
MDLMDKEJ_00613 1.7e-199 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MDLMDKEJ_00614 2.53e-152 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MDLMDKEJ_00615 2.43e-100 - - - - - - - -
MDLMDKEJ_00616 1.24e-113 - - - FG - - - HIT domain
MDLMDKEJ_00617 5.21e-82 - - - - - - - -
MDLMDKEJ_00618 4.91e-121 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDLMDKEJ_00619 1.62e-135 - - - S - - - Alpha/beta hydrolase family
MDLMDKEJ_00620 6.2e-131 - - - - - - - -
MDLMDKEJ_00621 1.22e-103 - - - - - - - -
MDLMDKEJ_00622 2.72e-188 - - - F - - - Phosphorylase superfamily
MDLMDKEJ_00623 3.34e-139 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
MDLMDKEJ_00624 2.07e-189 - - - F - - - Phosphorylase superfamily
MDLMDKEJ_00625 1.06e-185 - - - F - - - Phosphorylase superfamily
MDLMDKEJ_00626 1.79e-144 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
MDLMDKEJ_00627 1.24e-47 - - - - - - - -
MDLMDKEJ_00628 2.58e-67 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MDLMDKEJ_00629 9.6e-137 - - - - - - - -
MDLMDKEJ_00630 8.78e-52 - - - - - - - -
MDLMDKEJ_00631 3.77e-216 mleR - - K - - - LysR family
MDLMDKEJ_00632 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MDLMDKEJ_00633 3.74e-130 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MDLMDKEJ_00634 2.2e-310 - - - L ko:K07478 - ko00000 AAA C-terminal domain
MDLMDKEJ_00635 2.27e-248 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDLMDKEJ_00636 5.33e-147 - - - S - - - L,D-transpeptidase catalytic domain
MDLMDKEJ_00637 1.23e-278 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MDLMDKEJ_00638 3.03e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDLMDKEJ_00639 2.55e-118 - - - L - - - nuclease
MDLMDKEJ_00640 2.51e-198 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MDLMDKEJ_00641 2.81e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MDLMDKEJ_00642 5.39e-308 steT - - E ko:K03294 - ko00000 amino acid
MDLMDKEJ_00643 4.4e-138 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MDLMDKEJ_00644 6.01e-54 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MDLMDKEJ_00645 3.16e-190 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MDLMDKEJ_00646 0.0 ppc 4.1.1.31 - C ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate carboxylase activity
MDLMDKEJ_00647 0.0 - - - - - - - -
MDLMDKEJ_00648 0.0 - - - - - - - -
MDLMDKEJ_00649 2.29e-224 yobV3 - - K - - - WYL domain
MDLMDKEJ_00650 4.35e-108 - - - S - - - Pyridoxamine 5'-phosphate oxidase
MDLMDKEJ_00651 1.57e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
MDLMDKEJ_00652 3.78e-72 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MDLMDKEJ_00653 1.16e-148 - - - C - - - Aldo/keto reductase family
MDLMDKEJ_00654 7.12e-80 - - - C - - - aldo keto reductase
MDLMDKEJ_00655 1.54e-187 - - - U ko:K05340 - ko00000,ko02000 ribose uptake protein RbsU
MDLMDKEJ_00656 1.51e-24 - - - C - - - Flavodoxin
MDLMDKEJ_00658 9.87e-139 - - - C - - - Flavodoxin
MDLMDKEJ_00659 2.88e-130 - - - P - - - esterase
MDLMDKEJ_00660 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MDLMDKEJ_00661 3.77e-32 - - - - - - - -
MDLMDKEJ_00662 1.29e-182 - - - C - - - Flavodoxin
MDLMDKEJ_00663 7.38e-127 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
MDLMDKEJ_00664 3.1e-30 - - - C - - - Flavodoxin
MDLMDKEJ_00665 1.39e-190 - - - P - - - FAD-binding domain
MDLMDKEJ_00666 2.54e-101 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MDLMDKEJ_00668 0.0 yagE - - E - - - amino acid
MDLMDKEJ_00669 1.37e-15 - - - S - - - Alpha beta hydrolase
MDLMDKEJ_00670 6e-59 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDLMDKEJ_00671 4.13e-18 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDLMDKEJ_00672 1.43e-24 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MDLMDKEJ_00673 8.53e-215 - - - S - - - Conserved hypothetical protein 698
MDLMDKEJ_00674 1.17e-130 - - - - - - - -
MDLMDKEJ_00675 1.9e-140 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDLMDKEJ_00676 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDLMDKEJ_00677 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDLMDKEJ_00678 3.72e-237 - - - K - - - Transcriptional regulator
MDLMDKEJ_00679 3.65e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MDLMDKEJ_00680 7.02e-146 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDLMDKEJ_00681 9.73e-55 - - - K - - - Helix-turn-helix domain
MDLMDKEJ_00682 4.78e-165 - - - S - - - Protein of unknown function (DUF1275)
MDLMDKEJ_00683 3.46e-87 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
MDLMDKEJ_00685 2.5e-156 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDLMDKEJ_00686 2.69e-93 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDLMDKEJ_00687 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDLMDKEJ_00688 1.74e-272 - - - EGP - - - Transmembrane secretion effector
MDLMDKEJ_00689 1.06e-110 rmaD - - K - - - transcriptional
MDLMDKEJ_00690 3.92e-76 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDLMDKEJ_00691 3.43e-07 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MDLMDKEJ_00692 2.71e-256 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDLMDKEJ_00693 2.62e-138 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
MDLMDKEJ_00694 1.27e-119 flaR - - F - - - topology modulation protein
MDLMDKEJ_00695 1.03e-100 - - - - - - - -
MDLMDKEJ_00696 5.95e-250 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
MDLMDKEJ_00697 6.18e-205 - - - S - - - EDD domain protein, DegV family
MDLMDKEJ_00698 2.95e-87 - - - - - - - -
MDLMDKEJ_00699 0.0 FbpA - - K - - - Fibronectin-binding protein
MDLMDKEJ_00700 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MDLMDKEJ_00701 2.05e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MDLMDKEJ_00702 2.88e-219 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MDLMDKEJ_00703 6.03e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDLMDKEJ_00704 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MDLMDKEJ_00705 2.01e-310 cpdA - - S - - - Calcineurin-like phosphoesterase
MDLMDKEJ_00706 2.39e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MDLMDKEJ_00707 2.83e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDLMDKEJ_00708 1.61e-136 ypsA - - S - - - Belongs to the UPF0398 family
MDLMDKEJ_00709 1.99e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDLMDKEJ_00710 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MDLMDKEJ_00711 4.71e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDLMDKEJ_00712 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MDLMDKEJ_00713 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MDLMDKEJ_00714 8.23e-117 ypmB - - S - - - Protein conserved in bacteria
MDLMDKEJ_00715 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MDLMDKEJ_00716 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MDLMDKEJ_00717 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDLMDKEJ_00718 6.78e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
MDLMDKEJ_00719 3.39e-227 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MDLMDKEJ_00720 1.64e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MDLMDKEJ_00721 2.09e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDLMDKEJ_00722 1.01e-187 - - - K - - - SIS domain
MDLMDKEJ_00723 1.18e-140 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDLMDKEJ_00724 2.04e-73 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDLMDKEJ_00725 1.14e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MDLMDKEJ_00726 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MDLMDKEJ_00727 1.05e-228 - - - - - - - -
MDLMDKEJ_00728 1.57e-181 - - - - - - - -
MDLMDKEJ_00729 1.72e-123 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MDLMDKEJ_00730 1.04e-37 - - - - - - - -
MDLMDKEJ_00731 3.64e-175 - - - - - - - -
MDLMDKEJ_00732 2.03e-186 - - - - - - - -
MDLMDKEJ_00733 1.51e-174 - - - - - - - -
MDLMDKEJ_00734 1.09e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDLMDKEJ_00735 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MDLMDKEJ_00736 7.64e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MDLMDKEJ_00737 3.45e-197 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDLMDKEJ_00738 4.48e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MDLMDKEJ_00739 1.87e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MDLMDKEJ_00740 2.24e-162 - - - S - - - Peptidase family M23
MDLMDKEJ_00741 3.01e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDLMDKEJ_00742 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDLMDKEJ_00743 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MDLMDKEJ_00744 1.05e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MDLMDKEJ_00745 5.41e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MDLMDKEJ_00746 6.28e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDLMDKEJ_00747 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDLMDKEJ_00748 1.82e-226 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MDLMDKEJ_00749 4.38e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MDLMDKEJ_00750 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MDLMDKEJ_00751 4.68e-197 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MDLMDKEJ_00752 3.22e-133 - - - S - - - Peptidase family M23
MDLMDKEJ_00753 6.31e-144 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDLMDKEJ_00754 2.17e-209 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDLMDKEJ_00755 1.4e-157 - - - - - - - -
MDLMDKEJ_00756 4.04e-207 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MDLMDKEJ_00757 1.58e-282 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MDLMDKEJ_00758 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MDLMDKEJ_00759 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MDLMDKEJ_00760 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MDLMDKEJ_00761 3.65e-28 - - - S - - - Bacterial protein of unknown function (DUF898)
MDLMDKEJ_00762 1.92e-141 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MDLMDKEJ_00763 0.0 - - - - ko:K14201 ko05150,map05150 ko00000,ko00001 -
MDLMDKEJ_00764 2.86e-05 - - - M - - - Leucine-rich repeat (LRR) protein
MDLMDKEJ_00765 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MDLMDKEJ_00766 5.4e-282 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MDLMDKEJ_00767 0.0 - - - - - - - -
MDLMDKEJ_00768 3.69e-157 - - - G - - - Antibiotic biosynthesis monooxygenase
MDLMDKEJ_00769 8.29e-129 - - - - - - - -
MDLMDKEJ_00770 1.82e-139 - - - K - - - LysR substrate binding domain
MDLMDKEJ_00771 8.62e-22 - - - - - - - -
MDLMDKEJ_00772 3.35e-291 - - - S - - - Sterol carrier protein domain
MDLMDKEJ_00773 3.83e-127 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MDLMDKEJ_00774 3.72e-201 lysR5 - - K - - - LysR substrate binding domain
MDLMDKEJ_00775 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
MDLMDKEJ_00776 1.19e-113 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
MDLMDKEJ_00777 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDLMDKEJ_00778 4.53e-196 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MDLMDKEJ_00779 1.73e-219 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MDLMDKEJ_00780 1.72e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MDLMDKEJ_00781 6.15e-194 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MDLMDKEJ_00783 7.02e-103 - - - K - - - Acetyltransferase (GNAT) domain
MDLMDKEJ_00784 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDLMDKEJ_00785 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MDLMDKEJ_00786 6.07e-155 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
MDLMDKEJ_00787 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDLMDKEJ_00788 5.85e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDLMDKEJ_00789 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MDLMDKEJ_00790 7.55e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDLMDKEJ_00791 2.1e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDLMDKEJ_00792 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MDLMDKEJ_00793 2.49e-228 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MDLMDKEJ_00794 8.54e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDLMDKEJ_00795 9.65e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDLMDKEJ_00796 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDLMDKEJ_00797 3.95e-65 ylxQ - - J - - - ribosomal protein
MDLMDKEJ_00798 6.47e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MDLMDKEJ_00799 3.76e-268 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MDLMDKEJ_00800 2.39e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MDLMDKEJ_00801 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDLMDKEJ_00802 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDLMDKEJ_00803 1.35e-255 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MDLMDKEJ_00804 1.89e-188 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MDLMDKEJ_00805 2.23e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDLMDKEJ_00806 2.53e-114 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDLMDKEJ_00807 7.13e-169 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MDLMDKEJ_00808 1.45e-234 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDLMDKEJ_00809 2.05e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MDLMDKEJ_00810 6.34e-255 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MDLMDKEJ_00811 1.59e-149 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MDLMDKEJ_00812 9.32e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MDLMDKEJ_00813 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MDLMDKEJ_00814 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_00815 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_00816 3.18e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
MDLMDKEJ_00817 2.97e-50 ynzC - - S - - - UPF0291 protein
MDLMDKEJ_00818 2.83e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDLMDKEJ_00819 1.4e-185 - - - E - - - GDSL-like Lipase/Acylhydrolase family
MDLMDKEJ_00820 1.19e-156 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
MDLMDKEJ_00821 2.58e-226 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MDLMDKEJ_00822 0.0 - - - S - - - Bacterial membrane protein, YfhO
MDLMDKEJ_00823 3.52e-91 - - - S - - - GtrA-like protein
MDLMDKEJ_00824 2.28e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDLMDKEJ_00825 5.01e-164 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MDLMDKEJ_00826 1.07e-124 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDLMDKEJ_00827 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MDLMDKEJ_00828 1.9e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDLMDKEJ_00829 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDLMDKEJ_00830 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
MDLMDKEJ_00831 1.16e-88 - - - - - - - -
MDLMDKEJ_00832 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDLMDKEJ_00833 1.12e-228 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDLMDKEJ_00834 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MDLMDKEJ_00835 4.48e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDLMDKEJ_00839 2.83e-62 - - - - - - - -
MDLMDKEJ_00840 1.3e-99 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
MDLMDKEJ_00841 1.51e-234 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDLMDKEJ_00842 1.19e-160 - - - K - - - Bacterial regulatory proteins, tetR family
MDLMDKEJ_00843 2.93e-173 - - - - - - - -
MDLMDKEJ_00844 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_00845 7.42e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_00846 1.96e-293 - - - S - - - Cysteine-rich secretory protein family
MDLMDKEJ_00847 7.25e-265 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MDLMDKEJ_00848 1.49e-136 - - - - - - - -
MDLMDKEJ_00849 9.78e-258 yibE - - S - - - overlaps another CDS with the same product name
MDLMDKEJ_00850 1.71e-170 yibF - - S - - - overlaps another CDS with the same product name
MDLMDKEJ_00851 7.56e-205 - - - I - - - alpha/beta hydrolase fold
MDLMDKEJ_00852 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MDLMDKEJ_00853 8.53e-292 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MDLMDKEJ_00854 2.9e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
MDLMDKEJ_00855 1.74e-112 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MDLMDKEJ_00856 8.74e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MDLMDKEJ_00857 3.95e-113 usp5 - - T - - - universal stress protein
MDLMDKEJ_00858 7.56e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MDLMDKEJ_00859 4.46e-180 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MDLMDKEJ_00860 2.84e-171 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_00861 6.38e-191 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_00862 7.66e-141 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MDLMDKEJ_00863 3.65e-109 - - - - - - - -
MDLMDKEJ_00864 0.0 - - - S - - - Calcineurin-like phosphoesterase
MDLMDKEJ_00865 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MDLMDKEJ_00866 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MDLMDKEJ_00867 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MDLMDKEJ_00868 1.29e-178 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDLMDKEJ_00869 1.6e-127 yitW - - S - - - Iron-sulfur cluster assembly protein
MDLMDKEJ_00870 4.3e-297 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
MDLMDKEJ_00871 1.88e-292 yttB - - EGP - - - Major Facilitator
MDLMDKEJ_00872 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MDLMDKEJ_00873 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MDLMDKEJ_00874 6.3e-91 - - - - - - - -
MDLMDKEJ_00875 2.15e-21 - - - - - - - -
MDLMDKEJ_00876 3.76e-289 - - - S - - - SLAP domain
MDLMDKEJ_00877 4.97e-81 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
MDLMDKEJ_00878 0.0 icaA - - M - - - Glycosyl transferase family group 2
MDLMDKEJ_00879 2.3e-229 - - - - - - - -
MDLMDKEJ_00880 8.52e-304 - - - S - - - SLAP domain
MDLMDKEJ_00881 2.53e-283 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDLMDKEJ_00882 7.59e-269 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
MDLMDKEJ_00883 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MDLMDKEJ_00884 6.61e-230 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDLMDKEJ_00885 4.62e-181 - - - - - - - -
MDLMDKEJ_00886 2.12e-176 - - - - - - - -
MDLMDKEJ_00887 1.84e-170 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDLMDKEJ_00888 8.51e-143 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MDLMDKEJ_00889 1.96e-132 - - - G - - - Aldose 1-epimerase
MDLMDKEJ_00890 1.34e-259 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MDLMDKEJ_00891 2.73e-146 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDLMDKEJ_00892 0.0 XK27_08315 - - M - - - Sulfatase
MDLMDKEJ_00893 0.0 - - - S - - - Fibronectin type III domain
MDLMDKEJ_00894 6.28e-310 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDLMDKEJ_00895 1.02e-74 - - - - - - - -
MDLMDKEJ_00897 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MDLMDKEJ_00898 1.16e-162 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDLMDKEJ_00899 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MDLMDKEJ_00900 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MDLMDKEJ_00901 8.86e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDLMDKEJ_00902 5.46e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDLMDKEJ_00903 1.92e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MDLMDKEJ_00904 1.9e-256 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDLMDKEJ_00905 1.87e-221 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDLMDKEJ_00906 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MDLMDKEJ_00907 1.5e-96 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MDLMDKEJ_00908 6.92e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDLMDKEJ_00909 1.09e-148 - - - - - - - -
MDLMDKEJ_00911 1.21e-146 - - - E - - - Belongs to the SOS response-associated peptidase family
MDLMDKEJ_00912 2.35e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDLMDKEJ_00913 2.69e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
MDLMDKEJ_00914 1.25e-142 - - - S ko:K06872 - ko00000 TPM domain
MDLMDKEJ_00915 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MDLMDKEJ_00916 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDLMDKEJ_00917 2.33e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MDLMDKEJ_00918 1.63e-124 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDLMDKEJ_00919 4.9e-207 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDLMDKEJ_00920 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
MDLMDKEJ_00921 4.31e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MDLMDKEJ_00922 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDLMDKEJ_00923 1.4e-116 - - - S - - - SLAP domain
MDLMDKEJ_00924 4.55e-117 - - - S - - - SLAP domain
MDLMDKEJ_00925 1.48e-114 - - - - - - - -
MDLMDKEJ_00926 0.0 - - - S - - - SLAP domain
MDLMDKEJ_00927 6.58e-227 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDLMDKEJ_00928 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_00929 3.82e-167 yecA - - K - - - Helix-turn-helix domain, rpiR family
MDLMDKEJ_00930 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_00931 4.58e-216 - - - GK - - - ROK family
MDLMDKEJ_00932 4.88e-59 - - - - - - - -
MDLMDKEJ_00933 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDLMDKEJ_00934 4.39e-88 - - - S - - - Domain of unknown function (DUF1934)
MDLMDKEJ_00935 1.11e-96 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDLMDKEJ_00936 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDLMDKEJ_00937 6.32e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDLMDKEJ_00938 4.42e-142 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDLMDKEJ_00939 1.59e-205 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDLMDKEJ_00940 7.87e-207 msmR - - K - - - AraC-like ligand binding domain
MDLMDKEJ_00941 1.87e-137 ybbB - - S - - - Protein of unknown function (DUF1211)
MDLMDKEJ_00942 1.21e-285 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MDLMDKEJ_00943 5.8e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDLMDKEJ_00944 1.04e-173 - - - K - - - DNA-binding helix-turn-helix protein
MDLMDKEJ_00945 3.77e-220 - - - K - - - Helix-turn-helix
MDLMDKEJ_00946 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MDLMDKEJ_00947 7.77e-199 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_00948 3.12e-191 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MDLMDKEJ_00949 1.03e-96 - - - K - - - LytTr DNA-binding domain
MDLMDKEJ_00950 1.16e-63 - - - S - - - Protein of unknown function (DUF3021)
MDLMDKEJ_00951 7.88e-116 - - - K - - - Acetyltransferase (GNAT) domain
MDLMDKEJ_00952 9.09e-173 XK27_07210 - - S - - - B3 4 domain
MDLMDKEJ_00953 2.07e-117 - - - P - - - Belongs to the major facilitator superfamily
MDLMDKEJ_00954 2.89e-44 - - - P - - - Belongs to the major facilitator superfamily
MDLMDKEJ_00955 5.49e-42 - - - - - - - -
MDLMDKEJ_00956 3.18e-106 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MDLMDKEJ_00957 6.74e-39 - - - K ko:K12410 - ko00000,ko01000 NAD+ binding
MDLMDKEJ_00958 4.62e-13 - - - P - - - Voltage gated chloride channel
MDLMDKEJ_00959 7.47e-126 - - - - - - - -
MDLMDKEJ_00960 8.2e-68 - - - - - - - -
MDLMDKEJ_00961 4.88e-59 - - - - - - - -
MDLMDKEJ_00962 9.39e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDLMDKEJ_00963 0.0 - - - E - - - amino acid
MDLMDKEJ_00964 9.8e-204 supH 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MDLMDKEJ_00965 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MDLMDKEJ_00966 5.28e-53 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MDLMDKEJ_00967 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDLMDKEJ_00968 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDLMDKEJ_00969 3.27e-80 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDLMDKEJ_00970 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDLMDKEJ_00971 1.23e-166 - - - S - - - (CBS) domain
MDLMDKEJ_00972 1.98e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MDLMDKEJ_00973 6.58e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDLMDKEJ_00974 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDLMDKEJ_00975 1.79e-46 yabO - - J - - - S4 domain protein
MDLMDKEJ_00976 1.03e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
MDLMDKEJ_00977 3.95e-82 - - - J ko:K07571 - ko00000 S1 RNA binding domain
MDLMDKEJ_00978 5.11e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDLMDKEJ_00979 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDLMDKEJ_00980 6.77e-215 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDLMDKEJ_00981 3.5e-249 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDLMDKEJ_00982 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MDLMDKEJ_00986 1.16e-107 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MDLMDKEJ_00987 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDLMDKEJ_00988 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDLMDKEJ_00989 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDLMDKEJ_00990 6.6e-159 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
MDLMDKEJ_00991 2.09e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDLMDKEJ_00992 6.89e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDLMDKEJ_00993 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDLMDKEJ_00994 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MDLMDKEJ_00995 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDLMDKEJ_00996 1.91e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MDLMDKEJ_00997 3.57e-62 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDLMDKEJ_00998 9.85e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDLMDKEJ_00999 1.34e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDLMDKEJ_01000 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDLMDKEJ_01001 7.15e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDLMDKEJ_01002 9.64e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDLMDKEJ_01003 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MDLMDKEJ_01004 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDLMDKEJ_01005 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDLMDKEJ_01006 6.92e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDLMDKEJ_01007 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDLMDKEJ_01008 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDLMDKEJ_01009 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDLMDKEJ_01010 2.5e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDLMDKEJ_01011 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDLMDKEJ_01012 5.3e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDLMDKEJ_01013 1.1e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MDLMDKEJ_01014 2.45e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MDLMDKEJ_01015 3.59e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDLMDKEJ_01016 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDLMDKEJ_01017 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDLMDKEJ_01018 4.63e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MDLMDKEJ_01019 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDLMDKEJ_01020 3.95e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDLMDKEJ_01021 2.55e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDLMDKEJ_01022 1.57e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MDLMDKEJ_01023 4.16e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDLMDKEJ_01024 4.04e-206 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDLMDKEJ_01025 1.74e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDLMDKEJ_01026 4.17e-192 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDLMDKEJ_01027 1.6e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MDLMDKEJ_01028 8.28e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MDLMDKEJ_01029 7.71e-255 - - - L - - - Phage integrase family
MDLMDKEJ_01030 4.24e-37 - - - - - - - -
MDLMDKEJ_01031 1.31e-270 - - - EP - - - Plasmid replication protein
MDLMDKEJ_01032 1.77e-61 - - - - - - - -
MDLMDKEJ_01033 2.52e-264 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDLMDKEJ_01034 1.48e-69 - - - - - - - -
MDLMDKEJ_01036 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
MDLMDKEJ_01037 1.53e-85 - - - S - - - YjcQ protein
MDLMDKEJ_01039 5.27e-16 - - - - - - - -
MDLMDKEJ_01040 3.63e-141 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
MDLMDKEJ_01041 4.67e-154 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDLMDKEJ_01042 8.09e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
MDLMDKEJ_01043 6.91e-164 - - - G - - - Belongs to the phosphoglycerate mutase family
MDLMDKEJ_01044 5.3e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MDLMDKEJ_01045 1.14e-27 - - - - - - - -
MDLMDKEJ_01046 1.27e-104 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDLMDKEJ_01047 9.84e-236 - - - S - - - AAA domain
MDLMDKEJ_01048 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MDLMDKEJ_01049 9.95e-70 - - - - - - - -
MDLMDKEJ_01050 1.82e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
MDLMDKEJ_01051 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDLMDKEJ_01052 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDLMDKEJ_01053 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MDLMDKEJ_01054 6.01e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDLMDKEJ_01055 4.31e-179 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDLMDKEJ_01056 2.91e-121 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
MDLMDKEJ_01057 2.41e-45 - - - - - - - -
MDLMDKEJ_01058 6.48e-148 - - - - - - - -
MDLMDKEJ_01059 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MDLMDKEJ_01060 1.22e-220 - - - K - - - helix_turn_helix, arabinose operon control protein
MDLMDKEJ_01061 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDLMDKEJ_01062 1.72e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDLMDKEJ_01063 3.66e-132 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MDLMDKEJ_01064 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDLMDKEJ_01065 1.5e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDLMDKEJ_01066 2.83e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MDLMDKEJ_01067 1.8e-223 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MDLMDKEJ_01068 4.47e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MDLMDKEJ_01069 4.47e-186 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDLMDKEJ_01070 5.67e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDLMDKEJ_01071 1.74e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MDLMDKEJ_01072 3.62e-268 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
MDLMDKEJ_01073 1.86e-38 - - - - - - - -
MDLMDKEJ_01074 2.15e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDLMDKEJ_01075 9.31e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDLMDKEJ_01076 3.83e-167 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
MDLMDKEJ_01077 1.25e-147 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MDLMDKEJ_01078 4.9e-33 - - - - - - - -
MDLMDKEJ_01079 9.21e-120 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDLMDKEJ_01080 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDLMDKEJ_01081 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDLMDKEJ_01082 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDLMDKEJ_01083 5.84e-202 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_01084 1.28e-226 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_01085 8.73e-234 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDLMDKEJ_01086 1.43e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDLMDKEJ_01087 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDLMDKEJ_01088 3.16e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDLMDKEJ_01089 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDLMDKEJ_01090 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MDLMDKEJ_01091 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
MDLMDKEJ_01092 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MDLMDKEJ_01093 1.5e-68 - - - - - - - -
MDLMDKEJ_01094 3.29e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MDLMDKEJ_01095 5.27e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MDLMDKEJ_01096 1.37e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDLMDKEJ_01097 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MDLMDKEJ_01098 9.79e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MDLMDKEJ_01099 4.61e-313 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDLMDKEJ_01100 1.08e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDLMDKEJ_01101 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDLMDKEJ_01102 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDLMDKEJ_01103 2.53e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MDLMDKEJ_01104 2.88e-105 - - - S - - - ASCH
MDLMDKEJ_01105 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MDLMDKEJ_01106 1.52e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MDLMDKEJ_01107 1.84e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MDLMDKEJ_01108 3.76e-48 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDLMDKEJ_01109 5.86e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDLMDKEJ_01110 5.91e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDLMDKEJ_01111 1.28e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDLMDKEJ_01112 2.57e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MDLMDKEJ_01113 6.05e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDLMDKEJ_01114 3.69e-258 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MDLMDKEJ_01115 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MDLMDKEJ_01116 4.8e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MDLMDKEJ_01117 3.54e-192 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MDLMDKEJ_01118 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MDLMDKEJ_01119 3.98e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MDLMDKEJ_01120 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MDLMDKEJ_01121 4.41e-137 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MDLMDKEJ_01122 9.64e-141 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MDLMDKEJ_01123 7.45e-09 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_01124 9.58e-80 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_01125 7.38e-127 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_01126 3.88e-196 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
MDLMDKEJ_01127 0.0 - - - S - - - Predicted membrane protein (DUF2207)
MDLMDKEJ_01128 3.04e-198 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
MDLMDKEJ_01129 1.16e-162 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDLMDKEJ_01130 1.75e-95 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MDLMDKEJ_01132 4.22e-211 - - - S - - - Membrane
MDLMDKEJ_01133 1.75e-227 lipA - - I - - - Carboxylesterase family
MDLMDKEJ_01134 4.8e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
MDLMDKEJ_01135 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDLMDKEJ_01136 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDLMDKEJ_01137 1.84e-195 supH - - S - - - haloacid dehalogenase-like hydrolase
MDLMDKEJ_01138 1.64e-262 - - - - - - - -
MDLMDKEJ_01139 1.71e-211 - - - - - - - -
MDLMDKEJ_01140 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MDLMDKEJ_01141 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
MDLMDKEJ_01142 0.0 - 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_01143 7.89e-213 - 2.7.1.85 - GK ko:K18673 - ko00000,ko01000 ROK family
MDLMDKEJ_01144 3.58e-262 xylR - - GK - - - ROK family
MDLMDKEJ_01145 4.19e-302 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_01146 9.35e-128 - - - S - - - Bacterial PH domain
MDLMDKEJ_01147 3.5e-22 - - - - - - - -
MDLMDKEJ_01148 1.02e-85 - - - K - - - sequence-specific DNA binding
MDLMDKEJ_01149 2.45e-63 - - - S - - - Motility quorum-sensing regulator, toxin of MqsA
MDLMDKEJ_01150 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDLMDKEJ_01151 1.67e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MDLMDKEJ_01152 2.43e-62 - - - - - - - -
MDLMDKEJ_01153 1.74e-192 - - - U ko:K05340 - ko00000,ko02000 sugar transport
MDLMDKEJ_01154 0.0 - - - - - - - -
MDLMDKEJ_01155 2.73e-07 - - - D - - - Domain of Unknown Function (DUF1542)
MDLMDKEJ_01156 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MDLMDKEJ_01157 2.85e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MDLMDKEJ_01158 5.02e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDLMDKEJ_01159 3.43e-235 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MDLMDKEJ_01160 1.75e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDLMDKEJ_01161 1.94e-215 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDLMDKEJ_01162 7.44e-168 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDLMDKEJ_01163 2.73e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDLMDKEJ_01164 3.3e-152 - - - GM - - - NmrA-like family
MDLMDKEJ_01165 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MDLMDKEJ_01166 9.28e-317 eriC - - P ko:K03281 - ko00000 chloride
MDLMDKEJ_01167 1.86e-141 - - - O - - - Matrixin
MDLMDKEJ_01168 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
MDLMDKEJ_01169 3.89e-122 - - - K - - - acetyltransferase
MDLMDKEJ_01170 1.65e-66 - - - - - - - -
MDLMDKEJ_01171 2.34e-204 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MDLMDKEJ_01172 2.87e-62 - - - - - - - -
MDLMDKEJ_01173 7.22e-161 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MDLMDKEJ_01174 1.15e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDLMDKEJ_01175 2.66e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
MDLMDKEJ_01176 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDLMDKEJ_01178 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MDLMDKEJ_01179 7.81e-82 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MDLMDKEJ_01180 3.88e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MDLMDKEJ_01181 1.45e-149 ylbE - - GM - - - NAD(P)H-binding
MDLMDKEJ_01182 2.97e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MDLMDKEJ_01183 1.08e-85 - - - S - - - ASCH domain
MDLMDKEJ_01184 6.71e-153 - - - S - - - GyrI-like small molecule binding domain
MDLMDKEJ_01186 1.3e-206 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
MDLMDKEJ_01187 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
MDLMDKEJ_01190 2.26e-267 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
MDLMDKEJ_01191 1.63e-169 - - - T - - - Putative diguanylate phosphodiesterase
MDLMDKEJ_01192 8.74e-192 - - - T - - - EAL domain
MDLMDKEJ_01193 8.31e-313 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
MDLMDKEJ_01194 3.07e-119 - - - - - - - -
MDLMDKEJ_01195 9.37e-227 - - - C - - - Oxidoreductase
MDLMDKEJ_01197 4.69e-271 - - - L ko:K07496 - ko00000 TIGRFAM transposase, IS605 OrfB family
MDLMDKEJ_01198 4.27e-37 - - - C - - - pentaerythritol trinitrate reductase activity
MDLMDKEJ_01199 4.83e-141 pncA - - Q - - - Isochorismatase family
MDLMDKEJ_01200 2.86e-19 - - - - - - - -
MDLMDKEJ_01201 0.0 potE - - E - - - Amino Acid
MDLMDKEJ_01202 2.05e-163 - - - S - - - Alpha beta hydrolase
MDLMDKEJ_01204 1.31e-165 - - - - - - - -
MDLMDKEJ_01205 5.44e-163 - - - S - - - L-ascorbic acid biosynthetic process
MDLMDKEJ_01206 8.84e-93 - - - O - - - OsmC-like protein
MDLMDKEJ_01207 3.65e-272 - - - EGP - - - Major Facilitator Superfamily
MDLMDKEJ_01208 9.45e-298 sptS - - T - - - Histidine kinase
MDLMDKEJ_01209 1.28e-152 dltr - - K - - - response regulator
MDLMDKEJ_01210 4.2e-147 - - - T - - - Region found in RelA / SpoT proteins
MDLMDKEJ_01211 7.55e-241 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MDLMDKEJ_01212 1.31e-134 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MDLMDKEJ_01213 8.2e-81 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MDLMDKEJ_01214 1.63e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MDLMDKEJ_01215 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MDLMDKEJ_01216 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MDLMDKEJ_01217 3.33e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDLMDKEJ_01218 3.56e-196 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_01219 1.98e-200 msmF - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_01220 6.26e-309 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDLMDKEJ_01221 7.27e-206 lacR - - K - - - helix_turn_helix, arabinose operon control protein
MDLMDKEJ_01222 2.78e-98 - - - K - - - MerR HTH family regulatory protein
MDLMDKEJ_01223 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MDLMDKEJ_01224 4.02e-124 - - - S - - - Domain of unknown function (DUF4811)
MDLMDKEJ_01225 9.46e-67 - - - S - - - Domain of unknown function (DUF4160)
MDLMDKEJ_01226 1.53e-61 - - - - - - - -
MDLMDKEJ_01228 3.46e-53 - - - C - - - FMN binding
MDLMDKEJ_01229 1.42e-215 - - - S - - - SLAP domain
MDLMDKEJ_01230 6.76e-247 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MDLMDKEJ_01231 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MDLMDKEJ_01232 7.5e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDLMDKEJ_01233 9.91e-241 - - - M - - - domain protein
MDLMDKEJ_01234 1.51e-145 - - - - - - - -
MDLMDKEJ_01235 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
MDLMDKEJ_01236 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
MDLMDKEJ_01241 5.35e-289 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDLMDKEJ_01242 0.0 mdr - - EGP - - - Major Facilitator
MDLMDKEJ_01243 1.37e-36 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MDLMDKEJ_01244 1.29e-150 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MDLMDKEJ_01245 7.6e-118 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MDLMDKEJ_01246 7.75e-153 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MDLMDKEJ_01247 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MDLMDKEJ_01248 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MDLMDKEJ_01250 3.3e-94 - - - K - - - transcriptional regulator
MDLMDKEJ_01251 1.39e-22 - - - K - - - transcriptional regulator
MDLMDKEJ_01252 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
MDLMDKEJ_01253 6.41e-105 - - - S - - - Cupin domain
MDLMDKEJ_01254 0.0 - - - S - - - domain, Protein
MDLMDKEJ_01255 4.95e-53 - - - S - - - Enterocin A Immunity
MDLMDKEJ_01256 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
MDLMDKEJ_01257 3.16e-72 - - - - - - - -
MDLMDKEJ_01258 4.1e-251 flp - - V - - - Beta-lactamase
MDLMDKEJ_01259 1.19e-71 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
MDLMDKEJ_01261 3.95e-310 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MDLMDKEJ_01262 3.16e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDLMDKEJ_01263 1.06e-164 - - - M - - - ErfK YbiS YcfS YnhG
MDLMDKEJ_01264 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MDLMDKEJ_01265 1.48e-217 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MDLMDKEJ_01266 2.45e-246 - - - C - - - FMN-dependent dehydrogenase
MDLMDKEJ_01267 2.79e-154 - - - - - - - -
MDLMDKEJ_01268 1.34e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MDLMDKEJ_01269 3.09e-208 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MDLMDKEJ_01270 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MDLMDKEJ_01271 6.93e-72 yheA - - S - - - Belongs to the UPF0342 family
MDLMDKEJ_01272 8.31e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
MDLMDKEJ_01273 0.0 yhaN - - L - - - AAA domain
MDLMDKEJ_01274 3.19e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MDLMDKEJ_01275 3.26e-199 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDLMDKEJ_01276 3.51e-74 - - - - - - - -
MDLMDKEJ_01277 1.38e-102 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MDLMDKEJ_01278 3.15e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01279 3.37e-273 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MDLMDKEJ_01280 9.15e-165 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDLMDKEJ_01281 5.52e-71 ytpP - - CO - - - Thioredoxin
MDLMDKEJ_01282 3.06e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDLMDKEJ_01283 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MDLMDKEJ_01284 0.0 - - - - - - - -
MDLMDKEJ_01285 2.69e-191 - - - K - - - Helix-turn-helix domain, rpiR family
MDLMDKEJ_01286 2.24e-41 - 2.7.1.208, 2.7.1.211 - G ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MDLMDKEJ_01287 0.0 - - - G ko:K02755,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDLMDKEJ_01288 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_01289 1.09e-135 - - - S - - - Membrane
MDLMDKEJ_01290 2.45e-214 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
MDLMDKEJ_01291 6.25e-304 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
MDLMDKEJ_01292 5.44e-127 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MDLMDKEJ_01293 2.86e-146 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MDLMDKEJ_01294 2.45e-227 - - - S - - - SLAP domain
MDLMDKEJ_01295 0.0 - - - M - - - Peptidase family M1 domain
MDLMDKEJ_01296 2.76e-249 - - - S - - - Bacteriocin helveticin-J
MDLMDKEJ_01297 2.68e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
MDLMDKEJ_01298 5.58e-192 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MDLMDKEJ_01299 1.9e-160 - - - C - - - Flavodoxin
MDLMDKEJ_01300 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MDLMDKEJ_01301 7.36e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDLMDKEJ_01302 1.85e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDLMDKEJ_01303 1.24e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MDLMDKEJ_01304 1.88e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDLMDKEJ_01305 1.15e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDLMDKEJ_01306 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDLMDKEJ_01307 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDLMDKEJ_01308 3.52e-253 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MDLMDKEJ_01309 3.61e-144 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDLMDKEJ_01310 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MDLMDKEJ_01311 0.0 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MDLMDKEJ_01312 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDLMDKEJ_01313 6.72e-205 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDLMDKEJ_01314 5.52e-139 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDLMDKEJ_01315 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDLMDKEJ_01316 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
MDLMDKEJ_01317 5.35e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MDLMDKEJ_01318 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDLMDKEJ_01319 2.67e-96 - - - K - - - LytTr DNA-binding domain
MDLMDKEJ_01320 1.39e-92 - - - S - - - Protein of unknown function (DUF3021)
MDLMDKEJ_01321 1.92e-118 - - - - - - - -
MDLMDKEJ_01322 9.48e-95 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDLMDKEJ_01323 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MDLMDKEJ_01324 4.31e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDLMDKEJ_01325 8.82e-241 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MDLMDKEJ_01326 4.78e-253 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MDLMDKEJ_01327 1.66e-120 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MDLMDKEJ_01328 4.26e-273 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MDLMDKEJ_01329 8.11e-159 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDLMDKEJ_01330 4.06e-145 yqeK - - H - - - Hydrolase, HD family
MDLMDKEJ_01331 3.58e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDLMDKEJ_01332 9.35e-275 ylbM - - S - - - Belongs to the UPF0348 family
MDLMDKEJ_01333 3.14e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MDLMDKEJ_01334 6.08e-164 csrR - - K - - - response regulator
MDLMDKEJ_01335 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MDLMDKEJ_01336 1.89e-209 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDLMDKEJ_01337 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MDLMDKEJ_01338 3.67e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDLMDKEJ_01339 1.24e-83 yodB - - K - - - Transcriptional regulator, HxlR family
MDLMDKEJ_01340 2.59e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDLMDKEJ_01341 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDLMDKEJ_01342 3.63e-94 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDLMDKEJ_01343 1.6e-217 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
MDLMDKEJ_01344 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MDLMDKEJ_01345 3.51e-17 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MDLMDKEJ_01346 1.06e-69 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
MDLMDKEJ_01347 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MDLMDKEJ_01348 2.46e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
MDLMDKEJ_01349 0.0 - - - S - - - membrane
MDLMDKEJ_01350 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MDLMDKEJ_01351 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MDLMDKEJ_01352 3.23e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDLMDKEJ_01353 4.62e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
MDLMDKEJ_01354 4.01e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MDLMDKEJ_01355 1.48e-90 yqhL - - P - - - Rhodanese-like protein
MDLMDKEJ_01356 8.27e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDLMDKEJ_01357 4.04e-304 ynbB - - P - - - aluminum resistance
MDLMDKEJ_01358 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MDLMDKEJ_01359 7.05e-171 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MDLMDKEJ_01360 7.72e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01361 5.77e-214 - - - - - - - -
MDLMDKEJ_01362 2.37e-210 - - - - - - - -
MDLMDKEJ_01365 8.07e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MDLMDKEJ_01366 1.12e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDLMDKEJ_01367 0.0 glpK3 2.7.1.30 - G ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 FGGY family of carbohydrate kinases, C-terminal domain
MDLMDKEJ_01368 2.68e-225 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
MDLMDKEJ_01369 5.73e-202 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, thiamine diphosphate binding domain
MDLMDKEJ_01370 9.9e-240 purR13 - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
MDLMDKEJ_01371 1.41e-286 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
MDLMDKEJ_01372 0.0 - - - G - - - isomerase
MDLMDKEJ_01373 1.11e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDLMDKEJ_01374 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDLMDKEJ_01375 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MDLMDKEJ_01376 2.7e-10 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDLMDKEJ_01377 8.27e-190 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDLMDKEJ_01378 1.05e-225 - - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
MDLMDKEJ_01379 0.0 - - - G - - - Protein of unknown function (DUF4038)
MDLMDKEJ_01380 5.47e-199 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MDLMDKEJ_01381 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDLMDKEJ_01382 4.63e-225 - - - I - - - alpha/beta hydrolase fold
MDLMDKEJ_01383 9.97e-103 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
MDLMDKEJ_01384 2.11e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MDLMDKEJ_01385 0.0 yhdP - - S - - - Transporter associated domain
MDLMDKEJ_01386 9.09e-156 - - - C - - - nitroreductase
MDLMDKEJ_01387 1.51e-53 - - - - - - - -
MDLMDKEJ_01388 5.61e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MDLMDKEJ_01389 2.25e-105 - - - - - - - -
MDLMDKEJ_01390 1.1e-191 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MDLMDKEJ_01391 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MDLMDKEJ_01392 1.35e-196 - - - S - - - hydrolase
MDLMDKEJ_01393 5.93e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDLMDKEJ_01394 8.04e-187 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MDLMDKEJ_01395 7.37e-293 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MDLMDKEJ_01396 2.25e-206 - - - S - - - Phospholipase, patatin family
MDLMDKEJ_01397 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MDLMDKEJ_01398 3.4e-178 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MDLMDKEJ_01399 7.73e-79 - - - S - - - Enterocin A Immunity
MDLMDKEJ_01400 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MDLMDKEJ_01401 1.21e-93 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MDLMDKEJ_01402 2.07e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MDLMDKEJ_01403 0.0 - - - V - - - ABC transporter transmembrane region
MDLMDKEJ_01404 5.7e-146 - - - - - - - -
MDLMDKEJ_01405 1.81e-28 - - - - - - - -
MDLMDKEJ_01406 1.98e-175 gntR - - K - - - UbiC transcription regulator-associated domain protein
MDLMDKEJ_01407 3.51e-223 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
MDLMDKEJ_01408 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MDLMDKEJ_01409 3.83e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDLMDKEJ_01410 9.2e-214 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDLMDKEJ_01411 5.34e-211 - - - C - - - Domain of unknown function (DUF4931)
MDLMDKEJ_01412 5.02e-313 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDLMDKEJ_01413 2.75e-95 - - - - - - - -
MDLMDKEJ_01414 3.66e-224 - - - S - - - Protein of unknown function (DUF2974)
MDLMDKEJ_01415 8.28e-143 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_01416 1.43e-136 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_01417 4.3e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MDLMDKEJ_01418 2.39e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01419 1.92e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
MDLMDKEJ_01420 8.88e-132 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MDLMDKEJ_01421 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
MDLMDKEJ_01422 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01423 6.57e-102 - - - K - - - Transcriptional regulator, MarR family
MDLMDKEJ_01424 2.22e-192 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MDLMDKEJ_01425 1.4e-188 - - - - - - - -
MDLMDKEJ_01426 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MDLMDKEJ_01427 7.56e-267 pepA - - E - - - M42 glutamyl aminopeptidase
MDLMDKEJ_01428 1.11e-212 - - - S ko:K07088 - ko00000 Membrane transport protein
MDLMDKEJ_01429 3.81e-274 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
MDLMDKEJ_01430 0.0 qacA - - EGP - - - Major Facilitator
MDLMDKEJ_01431 2.03e-67 - 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MDLMDKEJ_01432 3.27e-110 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MDLMDKEJ_01433 1.39e-118 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDLMDKEJ_01434 5.36e-305 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MDLMDKEJ_01435 5.81e-165 XK27_08575 - - V ko:K06148 - ko00000,ko02000 cysteine transport
MDLMDKEJ_01436 5.13e-141 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MDLMDKEJ_01437 4.73e-206 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
MDLMDKEJ_01438 3.79e-101 - - - K - - - acetyltransferase
MDLMDKEJ_01439 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MDLMDKEJ_01440 1.25e-118 - - - K - - - Bacterial regulatory proteins, tetR family
MDLMDKEJ_01441 1.88e-174 - - - S - - - CAAX protease self-immunity
MDLMDKEJ_01442 0.0 qacA - - EGP - - - Major Facilitator
MDLMDKEJ_01447 3.49e-123 - - - K - - - Acetyltransferase (GNAT) domain
MDLMDKEJ_01448 9.05e-231 - - - L - - - Recombinase zinc beta ribbon domain
MDLMDKEJ_01449 3.28e-122 - - - L - - - Resolvase, N terminal domain
MDLMDKEJ_01450 2.98e-246 - - - L ko:K06400 - ko00000 Recombinase
MDLMDKEJ_01451 2.43e-76 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
MDLMDKEJ_01452 3.15e-62 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
MDLMDKEJ_01453 5.16e-146 ung2 - - L - - - Uracil-DNA glycosylase
MDLMDKEJ_01454 9.1e-148 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
MDLMDKEJ_01455 1.05e-124 dpsB - - P - - - Belongs to the Dps family
MDLMDKEJ_01456 5.51e-46 - - - C - - - Heavy-metal-associated domain
MDLMDKEJ_01457 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
MDLMDKEJ_01458 1.48e-82 - - - - - - - -
MDLMDKEJ_01459 4.2e-30 - - - - - - - -
MDLMDKEJ_01460 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDLMDKEJ_01461 1.28e-310 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
MDLMDKEJ_01462 4.94e-75 - - - - - - - -
MDLMDKEJ_01463 8.38e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
MDLMDKEJ_01464 2.37e-220 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MDLMDKEJ_01465 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDLMDKEJ_01466 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDLMDKEJ_01467 4.46e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDLMDKEJ_01468 7.29e-267 camS - - S - - - sex pheromone
MDLMDKEJ_01469 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDLMDKEJ_01470 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MDLMDKEJ_01471 1.02e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MDLMDKEJ_01473 6.32e-83 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MDLMDKEJ_01474 8.44e-177 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MDLMDKEJ_01475 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MDLMDKEJ_01476 3.89e-288 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MDLMDKEJ_01477 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MDLMDKEJ_01478 5.7e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDLMDKEJ_01479 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDLMDKEJ_01480 1.85e-264 - - - M - - - Glycosyl transferases group 1
MDLMDKEJ_01481 1.39e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MDLMDKEJ_01482 2.13e-92 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
MDLMDKEJ_01483 1.33e-160 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
MDLMDKEJ_01484 5.81e-272 - - - - - - - -
MDLMDKEJ_01487 0.0 slpX - - S - - - SLAP domain
MDLMDKEJ_01488 6.76e-227 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MDLMDKEJ_01490 3.18e-92 - - - EGP - - - Major Facilitator
MDLMDKEJ_01491 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
MDLMDKEJ_01492 8.89e-270 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDLMDKEJ_01493 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
MDLMDKEJ_01494 2.93e-199 msmG - - G ko:K02026,ko:K10122 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_01495 1.78e-209 - - - P ko:K10121 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MDLMDKEJ_01496 0.0 - - - G ko:K02027,ko:K10120 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDLMDKEJ_01497 7.11e-236 lacI - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDLMDKEJ_01498 9.11e-69 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MDLMDKEJ_01499 9.82e-156 - - - G - - - Antibiotic biosynthesis monooxygenase
MDLMDKEJ_01500 2.57e-139 - - - G - - - Histidine phosphatase superfamily (branch 1)
MDLMDKEJ_01501 1e-142 - - - G - - - Phosphoglycerate mutase family
MDLMDKEJ_01502 3.81e-253 - - - D - - - nuclear chromosome segregation
MDLMDKEJ_01503 2.62e-111 - - - M - - - LysM domain protein
MDLMDKEJ_01504 4.35e-207 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MDLMDKEJ_01505 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDLMDKEJ_01506 2.6e-19 - - - - - - - -
MDLMDKEJ_01507 1.48e-219 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
MDLMDKEJ_01508 3.99e-88 - - - - - - - -
MDLMDKEJ_01509 3.99e-45 - - - - - - - -
MDLMDKEJ_01510 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
MDLMDKEJ_01511 2.79e-296 - - - L - - - Belongs to the 'phage' integrase family
MDLMDKEJ_01512 6.89e-06 - - - - - - - -
MDLMDKEJ_01513 3.69e-244 - - - EP - - - Plasmid replication protein
MDLMDKEJ_01515 2.66e-270 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDLMDKEJ_01516 8.66e-76 - - - - - - - -
MDLMDKEJ_01518 8.37e-161 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
MDLMDKEJ_01519 1.41e-208 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
MDLMDKEJ_01520 0.0 - - - S - - - AAA ATPase domain
MDLMDKEJ_01521 0.0 - - - L - - - Type III restriction enzyme, res subunit
MDLMDKEJ_01523 8.42e-187 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MDLMDKEJ_01524 1.14e-294 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MDLMDKEJ_01525 4.47e-81 - - - - - - - -
MDLMDKEJ_01526 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
MDLMDKEJ_01527 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
MDLMDKEJ_01528 0.0 - - - S - - - TerB-C domain
MDLMDKEJ_01529 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MDLMDKEJ_01530 8.15e-94 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
MDLMDKEJ_01531 1.63e-175 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MDLMDKEJ_01532 1.47e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDLMDKEJ_01533 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDLMDKEJ_01534 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MDLMDKEJ_01535 2.27e-315 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MDLMDKEJ_01536 3.62e-89 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
MDLMDKEJ_01537 7.93e-206 - - - K - - - Transcriptional regulator
MDLMDKEJ_01538 2.86e-85 - - - S - - - Domain of unknown function (DUF956)
MDLMDKEJ_01539 1.18e-225 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MDLMDKEJ_01540 1.67e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MDLMDKEJ_01541 1.36e-241 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MDLMDKEJ_01543 6e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MDLMDKEJ_01544 1.35e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDLMDKEJ_01545 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_01546 8.05e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_01547 2.56e-110 - - - - - - - -
MDLMDKEJ_01548 2.49e-189 - - - K - - - Helix-turn-helix XRE-family like proteins
MDLMDKEJ_01551 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
MDLMDKEJ_01552 1.53e-118 ymdB - - S - - - Macro domain protein
MDLMDKEJ_01553 1.97e-280 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
MDLMDKEJ_01555 8.59e-148 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MDLMDKEJ_01556 3e-133 - - - EGP - - - Major Facilitator Superfamily
MDLMDKEJ_01557 9.68e-226 - - - - - - - -
MDLMDKEJ_01558 7.67e-80 lysM - - M - - - LysM domain
MDLMDKEJ_01559 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MDLMDKEJ_01560 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MDLMDKEJ_01561 2.13e-36 - - - - - - - -
MDLMDKEJ_01562 1.71e-282 - - - S - - - Putative peptidoglycan binding domain
MDLMDKEJ_01563 3.08e-204 - - - C - - - Domain of unknown function (DUF4931)
MDLMDKEJ_01564 3.44e-153 - - - - - - - -
MDLMDKEJ_01565 4.33e-185 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MDLMDKEJ_01566 1.19e-179 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
MDLMDKEJ_01567 9.98e-146 - - - G - - - phosphoglycerate mutase
MDLMDKEJ_01568 5.93e-124 - - - K - - - Bacterial regulatory proteins, tetR family
MDLMDKEJ_01569 1.43e-231 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_01570 3.26e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01571 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDLMDKEJ_01572 2e-26 - - - - - - - -
MDLMDKEJ_01573 7.21e-143 - - - K - - - WHG domain
MDLMDKEJ_01574 4.14e-126 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MDLMDKEJ_01575 6.34e-127 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
MDLMDKEJ_01576 9.1e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MDLMDKEJ_01577 6.64e-233 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDLMDKEJ_01578 8.5e-105 cvpA - - S - - - Colicin V production protein
MDLMDKEJ_01579 3.14e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MDLMDKEJ_01580 2.79e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MDLMDKEJ_01581 4.1e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MDLMDKEJ_01582 2.05e-199 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MDLMDKEJ_01583 2.22e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MDLMDKEJ_01584 1.39e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDLMDKEJ_01585 1.55e-177 - - - S - - - Protein of unknown function (DUF1129)
MDLMDKEJ_01586 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01587 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
MDLMDKEJ_01588 1.44e-157 vanR - - K - - - response regulator
MDLMDKEJ_01589 9.58e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
MDLMDKEJ_01590 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDLMDKEJ_01591 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MDLMDKEJ_01592 5.63e-64 - - - S - - - Enterocin A Immunity
MDLMDKEJ_01593 1.4e-69 - - - S - - - Enterocin A Immunity
MDLMDKEJ_01594 1.47e-45 - - - - - - - -
MDLMDKEJ_01595 9.17e-37 - - - - - - - -
MDLMDKEJ_01596 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
MDLMDKEJ_01597 2.62e-50 - - - S - - - Enterocin A Immunity
MDLMDKEJ_01598 5.21e-275 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDLMDKEJ_01599 2.71e-136 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MDLMDKEJ_01601 2.6e-141 - - - - - - - -
MDLMDKEJ_01604 2e-06 - - - - - - - -
MDLMDKEJ_01605 8.09e-298 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
MDLMDKEJ_01606 7.63e-190 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MDLMDKEJ_01609 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDLMDKEJ_01610 3.21e-136 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MDLMDKEJ_01611 1.21e-275 blpT - - - - - - -
MDLMDKEJ_01616 2.26e-29 - - - - - - - -
MDLMDKEJ_01617 9.7e-116 - - - - - - - -
MDLMDKEJ_01618 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
MDLMDKEJ_01619 6.68e-35 - - - - - - - -
MDLMDKEJ_01620 4.14e-89 - - - - - - - -
MDLMDKEJ_01621 2.89e-12 - - - - - - - -
MDLMDKEJ_01622 1.6e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01623 7.39e-276 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MDLMDKEJ_01624 5.63e-253 - - - S - - - Fic/DOC family
MDLMDKEJ_01625 3.67e-176 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MDLMDKEJ_01626 1.31e-216 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MDLMDKEJ_01627 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MDLMDKEJ_01628 4.7e-64 - - - S - - - Protein of unknown function (DUF3021)
MDLMDKEJ_01629 3e-98 - - - K - - - LytTr DNA-binding domain
MDLMDKEJ_01630 7.83e-60 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MDLMDKEJ_01631 1.79e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MDLMDKEJ_01632 6.65e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MDLMDKEJ_01633 6.99e-174 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MDLMDKEJ_01634 1.04e-82 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MDLMDKEJ_01635 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
MDLMDKEJ_01636 9.86e-59 - - - P ko:K03449 - ko00000,ko02000 transmembrane transport
MDLMDKEJ_01637 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MDLMDKEJ_01638 5.01e-293 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MDLMDKEJ_01639 2.7e-59 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MDLMDKEJ_01640 3.08e-81 - - - - - - - -
MDLMDKEJ_01641 0.0 - - - S - - - ABC transporter
MDLMDKEJ_01642 3.8e-176 - - - S - - - Putative threonine/serine exporter
MDLMDKEJ_01643 4.44e-110 - - - S - - - Threonine/Serine exporter, ThrE
MDLMDKEJ_01644 1.64e-47 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MDLMDKEJ_01645 1.08e-62 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MDLMDKEJ_01646 1.47e-70 yitW - - S - - - Iron-sulfur cluster assembly protein
MDLMDKEJ_01647 3.7e-175 - - - S - - - Peptidase_C39 like family
MDLMDKEJ_01648 1.36e-105 - - - - - - - -
MDLMDKEJ_01649 2.71e-233 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDLMDKEJ_01650 7.02e-103 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
MDLMDKEJ_01651 4.7e-143 - - - - - - - -
MDLMDKEJ_01652 0.0 - - - S - - - O-antigen ligase like membrane protein
MDLMDKEJ_01653 2.96e-56 - - - - - - - -
MDLMDKEJ_01654 6.94e-110 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
MDLMDKEJ_01655 7.09e-125 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MDLMDKEJ_01656 2.99e-176 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MDLMDKEJ_01657 1.4e-204 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MDLMDKEJ_01658 0.0 - - - M - - - Mycoplasma protein of unknown function, DUF285
MDLMDKEJ_01659 5.52e-241 - - - S - - - Cysteine-rich secretory protein family
MDLMDKEJ_01660 1.42e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDLMDKEJ_01661 5.44e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MDLMDKEJ_01662 1.01e-193 epsB - - M - - - biosynthesis protein
MDLMDKEJ_01663 5.93e-166 ywqD - - D - - - Capsular exopolysaccharide family
MDLMDKEJ_01664 6.17e-191 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MDLMDKEJ_01665 1.77e-159 epsE2 - - M - - - Bacterial sugar transferase
MDLMDKEJ_01666 4.02e-192 cps3J - - M - - - Domain of unknown function (DUF4422)
MDLMDKEJ_01667 2.65e-215 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MDLMDKEJ_01669 4.69e-158 - - - M - - - transferase activity, transferring glycosyl groups
MDLMDKEJ_01670 7.58e-244 XK27_01805 - - M - - - Glycosyltransferase like family 2
MDLMDKEJ_01671 1.86e-287 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
MDLMDKEJ_01672 1.31e-93 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MDLMDKEJ_01673 7.05e-126 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
MDLMDKEJ_01674 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MDLMDKEJ_01675 1.34e-298 - - - L - - - COG3547 Transposase and inactivated derivatives
MDLMDKEJ_01676 1.63e-175 - - - L ko:K07483 - ko00000 transposase activity
MDLMDKEJ_01677 2.52e-84 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
MDLMDKEJ_01679 0.0 - - - M - - - Rib/alpha-like repeat
MDLMDKEJ_01680 6.9e-220 - - - - - - - -
MDLMDKEJ_01681 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MDLMDKEJ_01682 1.8e-124 yobS - - K - - - Bacterial regulatory proteins, tetR family
MDLMDKEJ_01683 2.62e-198 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MDLMDKEJ_01684 7.19e-202 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MDLMDKEJ_01685 2.47e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MDLMDKEJ_01686 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
MDLMDKEJ_01687 1.68e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MDLMDKEJ_01688 1.24e-197 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MDLMDKEJ_01689 9.81e-259 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MDLMDKEJ_01690 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDLMDKEJ_01691 4.53e-203 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MDLMDKEJ_01692 4e-234 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
MDLMDKEJ_01693 4.72e-200 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MDLMDKEJ_01694 7.21e-150 yviA - - S - - - Protein of unknown function (DUF421)
MDLMDKEJ_01695 9.54e-97 - - - S - - - Protein of unknown function (DUF3290)
MDLMDKEJ_01696 0.0 - - - M - - - domain protein
MDLMDKEJ_01697 3.05e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MDLMDKEJ_01698 0.0 - - - - - - - -
MDLMDKEJ_01699 7.95e-64 - - - - - - - -
MDLMDKEJ_01700 9.1e-184 - - - S - - - PAS domain
MDLMDKEJ_01701 0.0 - - - V - - - ABC transporter transmembrane region
MDLMDKEJ_01702 5.44e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MDLMDKEJ_01703 2.91e-164 - - - T - - - Transcriptional regulatory protein, C terminal
MDLMDKEJ_01704 4.14e-312 - - - T - - - GHKL domain
MDLMDKEJ_01705 2.36e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
MDLMDKEJ_01706 1.34e-131 - - - S - - - Peptidase propeptide and YPEB domain
MDLMDKEJ_01707 4.9e-100 yybA - - K - - - Transcriptional regulator
MDLMDKEJ_01708 3.59e-123 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MDLMDKEJ_01709 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MDLMDKEJ_01710 2.28e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MDLMDKEJ_01711 9.2e-130 - - - S - - - Peptidase propeptide and YPEB domain
MDLMDKEJ_01712 8.57e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDLMDKEJ_01713 3.51e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MDLMDKEJ_01714 1.68e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
MDLMDKEJ_01715 1.25e-106 yjcF - - S - - - Acetyltransferase (GNAT) domain
MDLMDKEJ_01716 2.71e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MDLMDKEJ_01717 1.29e-140 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MDLMDKEJ_01718 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MDLMDKEJ_01719 2.14e-31 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDLMDKEJ_01720 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MDLMDKEJ_01721 1.69e-160 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
MDLMDKEJ_01722 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
MDLMDKEJ_01723 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MDLMDKEJ_01724 3.02e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01725 7.62e-308 - - - S - - - response to antibiotic
MDLMDKEJ_01726 1.39e-164 - - - - - - - -
MDLMDKEJ_01727 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MDLMDKEJ_01728 3.66e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MDLMDKEJ_01729 3.45e-64 - - - - - - - -
MDLMDKEJ_01730 1.25e-22 - - - - - - - -
MDLMDKEJ_01731 1.35e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
MDLMDKEJ_01732 7.07e-178 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MDLMDKEJ_01733 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MDLMDKEJ_01734 8.44e-201 - - - - - - - -
MDLMDKEJ_01735 1.6e-119 - - - - - - - -
MDLMDKEJ_01736 3.39e-138 - - - K ko:K06977 - ko00000 acetyltransferase
MDLMDKEJ_01739 0.0 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
MDLMDKEJ_01740 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
MDLMDKEJ_01741 5.59e-250 - - - S - - - Domain of unknown function (DUF4767)
MDLMDKEJ_01742 1.56e-256 - - - S - - - Membrane
MDLMDKEJ_01743 1.71e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MDLMDKEJ_01744 7.86e-240 - - - K - - - helix_turn_helix, arabinose operon control protein
MDLMDKEJ_01745 3.86e-239 - - - K - - - helix_turn_helix, arabinose operon control protein
MDLMDKEJ_01746 1.96e-192 yleF - - K - - - Helix-turn-helix domain, rpiR family
MDLMDKEJ_01747 1.06e-258 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MDLMDKEJ_01748 1.24e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MDLMDKEJ_01749 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDLMDKEJ_01750 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MDLMDKEJ_01751 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDLMDKEJ_01752 4.37e-205 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MDLMDKEJ_01753 0.0 - - - M - - - Leucine-rich repeat (LRR) protein
MDLMDKEJ_01755 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
MDLMDKEJ_01756 4.05e-119 - - - - - - - -
MDLMDKEJ_01757 6.91e-235 - - - - - - - -
MDLMDKEJ_01758 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
MDLMDKEJ_01765 1.31e-211 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MDLMDKEJ_01766 2.29e-166 - - - K - - - helix_turn_helix, mercury resistance
MDLMDKEJ_01767 4.08e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MDLMDKEJ_01768 3.14e-226 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MDLMDKEJ_01769 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MDLMDKEJ_01770 8.03e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
MDLMDKEJ_01771 2.47e-32 - - - - - - - -
MDLMDKEJ_01772 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MDLMDKEJ_01773 6.78e-100 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
MDLMDKEJ_01774 1.77e-85 - - - S - - - Cupredoxin-like domain
MDLMDKEJ_01775 1.09e-65 - - - S - - - Cupredoxin-like domain
MDLMDKEJ_01776 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MDLMDKEJ_01777 2.91e-234 - - - S - - - DUF218 domain
MDLMDKEJ_01778 6.11e-168 - - - S - - - Mitochondrial biogenesis AIM24
MDLMDKEJ_01779 6.65e-153 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
MDLMDKEJ_01780 1.78e-26 - - - - - - - -
MDLMDKEJ_01781 5.17e-273 - - - - - - - -
MDLMDKEJ_01782 0.0 eriC - - P ko:K03281 - ko00000 chloride
MDLMDKEJ_01783 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDLMDKEJ_01784 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MDLMDKEJ_01785 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDLMDKEJ_01786 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDLMDKEJ_01787 2.31e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDLMDKEJ_01788 1.87e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDLMDKEJ_01789 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MDLMDKEJ_01790 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDLMDKEJ_01791 1.46e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDLMDKEJ_01792 6.15e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MDLMDKEJ_01793 3.1e-269 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDLMDKEJ_01794 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDLMDKEJ_01795 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDLMDKEJ_01796 9.55e-66 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MDLMDKEJ_01797 8.43e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDLMDKEJ_01798 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDLMDKEJ_01799 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MDLMDKEJ_01800 6.96e-100 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MDLMDKEJ_01801 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MDLMDKEJ_01802 1e-220 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
MDLMDKEJ_01803 1.38e-225 degV1 - - S - - - DegV family
MDLMDKEJ_01804 1.09e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
MDLMDKEJ_01805 1.38e-33 - - - S - - - CsbD-like
MDLMDKEJ_01806 1.47e-41 - - - S - - - Transglycosylase associated protein
MDLMDKEJ_01807 1.25e-303 - - - I - - - Protein of unknown function (DUF2974)
MDLMDKEJ_01809 7.47e-133 cadD - - P - - - Cadmium resistance transporter
MDLMDKEJ_01810 2.41e-77 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MDLMDKEJ_01811 2.93e-235 - - - - - - - -
MDLMDKEJ_01812 1.08e-71 - - - - - - - -
MDLMDKEJ_01813 7.23e-264 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MDLMDKEJ_01814 4.15e-120 - - - - - - - -
MDLMDKEJ_01815 1.16e-234 - - - EP - - - Plasmid replication protein
MDLMDKEJ_01816 1.45e-42 - - - - - - - -
MDLMDKEJ_01817 8.39e-299 - - - L - - - Belongs to the 'phage' integrase family
MDLMDKEJ_01818 4.37e-43 - - - - - - - -
MDLMDKEJ_01819 4.41e-92 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
MDLMDKEJ_01820 1.63e-27 - - - S - - - Protein of unknown function (DUF3923)
MDLMDKEJ_01823 2.01e-205 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
MDLMDKEJ_01824 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MDLMDKEJ_01825 1.5e-295 - - - S - - - LPXTG cell wall anchor motif
MDLMDKEJ_01826 1.4e-196 - - - S - - - Putative ABC-transporter type IV
MDLMDKEJ_01827 2.37e-129 - - - S - - - Cob(I)alamin adenosyltransferase
MDLMDKEJ_01828 6.12e-112 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
MDLMDKEJ_01829 9.95e-75 - - - S - - - Domain of unknown function (DUF4430)
MDLMDKEJ_01830 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
MDLMDKEJ_01831 2e-223 ydbI - - K - - - AI-2E family transporter
MDLMDKEJ_01832 2.37e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
MDLMDKEJ_01833 9.67e-22 - - - - - - - -
MDLMDKEJ_01834 2.79e-313 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
MDLMDKEJ_01835 6.35e-69 - - - - - - - -
MDLMDKEJ_01836 8.29e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MDLMDKEJ_01837 3.51e-170 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MDLMDKEJ_01838 3.82e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MDLMDKEJ_01839 1.29e-178 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MDLMDKEJ_01840 0.0 fusA1 - - J - - - elongation factor G
MDLMDKEJ_01841 1.99e-195 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MDLMDKEJ_01842 9.66e-41 - - - S - - - endonuclease exonuclease phosphatase family protein
MDLMDKEJ_01843 1.63e-172 - - - S - - - endonuclease exonuclease phosphatase family protein
MDLMDKEJ_01844 5.27e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDLMDKEJ_01845 3.08e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MDLMDKEJ_01846 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
MDLMDKEJ_01847 0.0 - - - L - - - Helicase C-terminal domain protein
MDLMDKEJ_01848 3.12e-273 pbpX1 - - V - - - Beta-lactamase
MDLMDKEJ_01849 6.19e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDLMDKEJ_01850 4.65e-193 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MDLMDKEJ_01851 1.45e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MDLMDKEJ_01852 3.19e-139 - - - S - - - Protein of unknown function (DUF1461)
MDLMDKEJ_01853 1.9e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDLMDKEJ_01854 6.99e-134 yutD - - S - - - Protein of unknown function (DUF1027)
MDLMDKEJ_01855 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MDLMDKEJ_01856 2.5e-74 - - - - - - - -
MDLMDKEJ_01857 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MDLMDKEJ_01858 4.5e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MDLMDKEJ_01859 4.1e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MDLMDKEJ_01860 1.37e-74 - - - - - - - -
MDLMDKEJ_01861 2.09e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDLMDKEJ_01862 3.18e-165 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MDLMDKEJ_01863 1.42e-143 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDLMDKEJ_01864 1.33e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MDLMDKEJ_01865 2.57e-91 yslB - - S - - - Protein of unknown function (DUF2507)
MDLMDKEJ_01866 1.46e-70 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDLMDKEJ_01867 1.54e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MDLMDKEJ_01868 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDLMDKEJ_01869 2.03e-67 yrzB - - S - - - Belongs to the UPF0473 family
MDLMDKEJ_01870 3.27e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDLMDKEJ_01871 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
MDLMDKEJ_01872 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDLMDKEJ_01873 8.26e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDLMDKEJ_01874 9.43e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MDLMDKEJ_01875 1.32e-255 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MDLMDKEJ_01876 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDLMDKEJ_01877 2.41e-83 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MDLMDKEJ_01878 1.61e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDLMDKEJ_01879 2.35e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDLMDKEJ_01880 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDLMDKEJ_01881 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDLMDKEJ_01882 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDLMDKEJ_01883 2.22e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDLMDKEJ_01884 2.29e-175 - - - S - - - membrane
MDLMDKEJ_01885 1.33e-100 - - - K - - - LytTr DNA-binding domain
MDLMDKEJ_01886 4.92e-107 - - - - - - - -
MDLMDKEJ_01887 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MDLMDKEJ_01888 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MDLMDKEJ_01889 6.41e-236 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
MDLMDKEJ_01890 1.24e-145 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDLMDKEJ_01891 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MDLMDKEJ_01892 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MDLMDKEJ_01893 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDLMDKEJ_01894 1.38e-298 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDLMDKEJ_01895 4.46e-165 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
MDLMDKEJ_01896 7.2e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MDLMDKEJ_01897 9.05e-170 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDLMDKEJ_01898 5.62e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDLMDKEJ_01899 1.49e-138 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MDLMDKEJ_01900 8.02e-172 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MDLMDKEJ_01901 6.76e-114 - - - S - - - ECF transporter, substrate-specific component
MDLMDKEJ_01902 1.29e-182 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MDLMDKEJ_01903 9.46e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDLMDKEJ_01904 2.65e-80 yabA - - L - - - Involved in initiation control of chromosome replication
MDLMDKEJ_01905 5.91e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MDLMDKEJ_01906 1.85e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
MDLMDKEJ_01907 1.69e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDLMDKEJ_01908 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
MDLMDKEJ_01909 4.56e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDLMDKEJ_01910 2.2e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)