ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HJKBDKNK_00001 6.61e-80 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HJKBDKNK_00002 8.63e-56 - - - L ko:K07484 - ko00000 Transposase IS66 family
HJKBDKNK_00004 1.36e-264 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HJKBDKNK_00005 1.02e-312 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HJKBDKNK_00006 7.97e-108 yvbK - - K - - - GNAT family
HJKBDKNK_00007 3.53e-61 - - - - - - - -
HJKBDKNK_00008 2.55e-51 - - - - - - - -
HJKBDKNK_00009 2.88e-61 pnb - - C - - - nitroreductase
HJKBDKNK_00010 1.32e-67 pnb - - C - - - nitroreductase
HJKBDKNK_00012 3.03e-36 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HJKBDKNK_00013 2.87e-217 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HJKBDKNK_00014 1.07e-88 - - - S - - - Protein of unknown function (DUF3021)
HJKBDKNK_00015 2.03e-100 - - - K - - - LytTr DNA-binding domain
HJKBDKNK_00016 4.9e-118 - - - K - - - Acetyltransferase (GNAT) family
HJKBDKNK_00017 1.21e-26 - - - - - - - -
HJKBDKNK_00018 3.86e-95 - - - P - - - Major Facilitator Superfamily
HJKBDKNK_00019 3.08e-151 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HJKBDKNK_00020 4.36e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HJKBDKNK_00021 3.91e-248 - - - S - - - Protein of unknown function (DUF3114)
HJKBDKNK_00022 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HJKBDKNK_00023 1.07e-212 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HJKBDKNK_00024 2.43e-134 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HJKBDKNK_00025 4.62e-81 - - - S - - - Domain of unknown function (DUF4828)
HJKBDKNK_00026 3.09e-244 mocA - - S - - - Oxidoreductase
HJKBDKNK_00027 4.69e-298 yfmL - - L - - - DEAD DEAH box helicase
HJKBDKNK_00029 4.92e-265 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HJKBDKNK_00030 7.85e-42 - - - - - - - -
HJKBDKNK_00031 7.03e-23 - - - - - - - -
HJKBDKNK_00032 2.45e-88 gtcA - - S - - - Teichoic acid glycosylation protein
HJKBDKNK_00033 4.7e-103 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HJKBDKNK_00034 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HJKBDKNK_00035 8.03e-280 arcT - - E - - - Aminotransferase
HJKBDKNK_00036 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HJKBDKNK_00037 0.0 potE - - E - - - Amino Acid
HJKBDKNK_00038 3.38e-195 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HJKBDKNK_00039 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
HJKBDKNK_00040 2.53e-42 - - - - - - - -
HJKBDKNK_00041 1.27e-178 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HJKBDKNK_00042 8.11e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
HJKBDKNK_00043 1.48e-220 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HJKBDKNK_00044 5.7e-153 - - - M - - - Bacterial sugar transferase
HJKBDKNK_00045 0.0 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
HJKBDKNK_00046 0.0 - - - G - - - Peptidase_C39 like family
HJKBDKNK_00047 4.46e-46 - - - - - - - -
HJKBDKNK_00048 4.12e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HJKBDKNK_00049 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HJKBDKNK_00050 2.59e-277 cps3F - - - - - - -
HJKBDKNK_00051 2.37e-127 - - - M - - - biosynthesis protein
HJKBDKNK_00052 1.16e-184 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HJKBDKNK_00053 1.85e-152 - - - M - - - Domain of unknown function (DUF4422)
HJKBDKNK_00054 3.06e-173 - - - S - - - Glycosyltransferase like family
HJKBDKNK_00055 4.77e-83 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HJKBDKNK_00056 1.65e-216 ykoT - - M - - - Glycosyl transferase family 2
HJKBDKNK_00057 0.0 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HJKBDKNK_00058 2.34e-207 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HJKBDKNK_00059 2.27e-139 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HJKBDKNK_00060 6.66e-263 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HJKBDKNK_00061 2.73e-201 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HJKBDKNK_00062 0.0 csd1 3.5.1.28 - M ko:K01447,ko:K17733,ko:K19117 - ko00000,ko01000,ko01002,ko01011,ko02048 N-Acetylmuramoyl-L-alanine amidase
HJKBDKNK_00063 9.19e-233 yueF - - S - - - AI-2E family transporter
HJKBDKNK_00064 5.61e-300 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HJKBDKNK_00065 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HJKBDKNK_00066 0.0 - - - M - - - NlpC/P60 family
HJKBDKNK_00067 8.85e-166 - - - M - - - NlpC/P60 family
HJKBDKNK_00068 0.0 - - - S - - - Peptidase, M23
HJKBDKNK_00069 7.18e-86 - - - K - - - Transcriptional regulator, GntR family
HJKBDKNK_00070 4.31e-198 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00071 5.54e-146 - - - - - - - -
HJKBDKNK_00072 1.57e-181 - - - G - - - MucBP domain
HJKBDKNK_00073 3.02e-128 - - - S - - - Pfam:DUF3816
HJKBDKNK_00074 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HJKBDKNK_00075 5.62e-37 - - - - - - - -
HJKBDKNK_00076 2.8e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HJKBDKNK_00077 1.23e-288 - - - L ko:K07484 - ko00000 Transposase IS66 family
HJKBDKNK_00079 2.67e-251 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HJKBDKNK_00080 6.7e-205 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HJKBDKNK_00081 1.08e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HJKBDKNK_00082 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HJKBDKNK_00083 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
HJKBDKNK_00084 6.9e-77 - - - - - - - -
HJKBDKNK_00085 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HJKBDKNK_00086 9.98e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HJKBDKNK_00087 9.94e-73 ftsL - - D - - - Cell division protein FtsL
HJKBDKNK_00088 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HJKBDKNK_00089 9.02e-229 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HJKBDKNK_00090 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HJKBDKNK_00091 9.81e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HJKBDKNK_00092 9.55e-183 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HJKBDKNK_00093 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HJKBDKNK_00094 8.44e-284 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HJKBDKNK_00095 1.11e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HJKBDKNK_00096 3.2e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HJKBDKNK_00097 1.76e-188 ylmH - - S - - - S4 domain protein
HJKBDKNK_00098 8.87e-101 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HJKBDKNK_00099 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HJKBDKNK_00100 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HJKBDKNK_00101 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HJKBDKNK_00102 8.37e-26 - - - - - - - -
HJKBDKNK_00103 6.59e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HJKBDKNK_00104 4.48e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HJKBDKNK_00105 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
HJKBDKNK_00106 8.77e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HJKBDKNK_00107 5.71e-159 pgm6 - - G - - - phosphoglycerate mutase
HJKBDKNK_00108 5.21e-155 - - - S - - - repeat protein
HJKBDKNK_00109 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HJKBDKNK_00110 3.49e-222 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HJKBDKNK_00111 2.6e-233 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HJKBDKNK_00112 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HJKBDKNK_00113 6.31e-309 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HJKBDKNK_00114 4.39e-110 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HJKBDKNK_00115 2.32e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HJKBDKNK_00116 1.09e-221 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HJKBDKNK_00117 1.56e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HJKBDKNK_00118 5.91e-279 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_00119 4.47e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HJKBDKNK_00120 5.77e-104 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
HJKBDKNK_00121 6.34e-279 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HJKBDKNK_00122 3.74e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HJKBDKNK_00123 2.15e-75 - - - - - - - -
HJKBDKNK_00125 2.51e-217 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HJKBDKNK_00126 4.37e-39 - - - - - - - -
HJKBDKNK_00127 2.05e-230 - - - I - - - Diacylglycerol kinase catalytic
HJKBDKNK_00128 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
HJKBDKNK_00129 3.66e-103 - - - - - - - -
HJKBDKNK_00130 2.78e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HJKBDKNK_00131 6.71e-265 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HJKBDKNK_00132 1.34e-231 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HJKBDKNK_00133 1.23e-310 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HJKBDKNK_00134 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HJKBDKNK_00135 7.63e-59 yktA - - S - - - Belongs to the UPF0223 family
HJKBDKNK_00136 4.59e-173 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HJKBDKNK_00137 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HJKBDKNK_00138 6.19e-283 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HJKBDKNK_00139 6.37e-60 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HJKBDKNK_00140 2.66e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HJKBDKNK_00141 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HJKBDKNK_00142 9.65e-249 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HJKBDKNK_00143 3.4e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HJKBDKNK_00144 2.47e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HJKBDKNK_00145 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HJKBDKNK_00146 2.27e-200 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HJKBDKNK_00149 1.16e-114 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HJKBDKNK_00150 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HJKBDKNK_00151 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HJKBDKNK_00152 7.68e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HJKBDKNK_00153 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HJKBDKNK_00154 9.28e-170 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HJKBDKNK_00155 1.04e-124 - - - S - - - Protein of unknown function (DUF1700)
HJKBDKNK_00156 4.63e-74 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HJKBDKNK_00157 3.29e-62 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HJKBDKNK_00158 1.32e-64 - - - - - - - -
HJKBDKNK_00159 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HJKBDKNK_00160 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HJKBDKNK_00161 8.87e-268 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HJKBDKNK_00162 1.19e-195 - - - M - - - Glycosyl transferase family group 2
HJKBDKNK_00163 7.72e-42 - - - M - - - Glycosyl transferase family group 2
HJKBDKNK_00165 1.21e-284 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HJKBDKNK_00166 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HJKBDKNK_00167 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HJKBDKNK_00168 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HJKBDKNK_00169 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HJKBDKNK_00170 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HJKBDKNK_00171 1.82e-175 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJKBDKNK_00172 3.58e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HJKBDKNK_00173 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HJKBDKNK_00174 5.49e-262 yacL - - S - - - domain protein
HJKBDKNK_00175 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HJKBDKNK_00176 1.02e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HJKBDKNK_00177 4.73e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HJKBDKNK_00178 6.88e-160 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HJKBDKNK_00179 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HJKBDKNK_00180 3.37e-178 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HJKBDKNK_00181 1.01e-172 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00182 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HJKBDKNK_00183 1.74e-273 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HJKBDKNK_00184 1.48e-214 - - - I - - - alpha/beta hydrolase fold
HJKBDKNK_00185 1.02e-170 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HJKBDKNK_00186 0.0 - - - S - - - Bacterial membrane protein, YfhO
HJKBDKNK_00187 3.71e-235 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HJKBDKNK_00188 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HJKBDKNK_00189 3.71e-67 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HJKBDKNK_00190 4.35e-92 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HJKBDKNK_00191 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HJKBDKNK_00192 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 DEAD/DEAH box helicase
HJKBDKNK_00194 3.08e-107 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HJKBDKNK_00195 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HJKBDKNK_00196 8.74e-196 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HJKBDKNK_00197 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HJKBDKNK_00198 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HJKBDKNK_00199 3.53e-168 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HJKBDKNK_00200 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HJKBDKNK_00201 3.57e-316 - - - EGP - - - Major Facilitator
HJKBDKNK_00202 1.14e-145 - - - - - - - -
HJKBDKNK_00205 5.86e-190 - - - S - - - Calcineurin-like phosphoesterase
HJKBDKNK_00206 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HJKBDKNK_00209 1.31e-216 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HJKBDKNK_00210 1.15e-41 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HJKBDKNK_00211 1.21e-76 - - - IQ - - - dehydrogenase reductase
HJKBDKNK_00212 1.3e-48 - - - - - - - -
HJKBDKNK_00213 9.4e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HJKBDKNK_00214 4.47e-50 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
HJKBDKNK_00215 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HJKBDKNK_00216 1.62e-231 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HJKBDKNK_00218 1.56e-126 - - - S ko:K07002 - ko00000 Serine hydrolase
HJKBDKNK_00219 4.48e-37 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HJKBDKNK_00220 5.03e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HJKBDKNK_00222 2.3e-228 ydhF - - S - - - Aldo keto reductase
HJKBDKNK_00223 2.43e-105 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
HJKBDKNK_00224 0.0 - - - L - - - Helicase C-terminal domain protein
HJKBDKNK_00226 2.48e-309 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HJKBDKNK_00227 1.85e-69 - - - S - - - Sugar efflux transporter for intercellular exchange
HJKBDKNK_00228 2.12e-162 - - - - - - - -
HJKBDKNK_00229 4.58e-162 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HJKBDKNK_00230 0.0 cadA - - P - - - P-type ATPase
HJKBDKNK_00231 5.95e-282 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
HJKBDKNK_00232 4.44e-11 - - - - - - - -
HJKBDKNK_00233 2.68e-45 - - - GM - - - NAD(P)H-binding
HJKBDKNK_00234 7.59e-66 - - - GM - - - NAD(P)H-binding
HJKBDKNK_00235 1.06e-94 ywnA - - K - - - Transcriptional regulator
HJKBDKNK_00236 3.07e-208 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HJKBDKNK_00237 7.85e-138 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HJKBDKNK_00238 3.69e-183 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00239 1.32e-136 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HJKBDKNK_00240 7.7e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HJKBDKNK_00241 3.02e-82 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HJKBDKNK_00242 2.48e-274 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HJKBDKNK_00243 1.45e-56 eriC - - P ko:K03281 - ko00000 chloride
HJKBDKNK_00244 2.71e-71 eriC - - P ko:K03281 - ko00000 chloride
HJKBDKNK_00245 2.1e-270 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HJKBDKNK_00246 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HJKBDKNK_00247 1.41e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HJKBDKNK_00248 2.06e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HJKBDKNK_00249 7e-215 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HJKBDKNK_00250 1.7e-280 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HJKBDKNK_00251 5.74e-54 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
HJKBDKNK_00252 2.83e-152 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HJKBDKNK_00253 3.44e-237 - - - L - - - PFAM Integrase catalytic region
HJKBDKNK_00254 1.45e-49 dpnM 2.1.1.72 - H ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 Site-specific DNA-methyltransferase (adenine-specific)
HJKBDKNK_00255 1.85e-127 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HJKBDKNK_00256 2.32e-146 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HJKBDKNK_00257 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HJKBDKNK_00258 2.35e-215 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HJKBDKNK_00260 6.57e-121 - - - J - - - Aminoglycoside-2''-adenylyltransferase
HJKBDKNK_00261 1.99e-38 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HJKBDKNK_00262 1.02e-77 - - - - - - - -
HJKBDKNK_00263 7.54e-286 - - - - - - - -
HJKBDKNK_00265 7.42e-59 - - - - - - - -
HJKBDKNK_00266 4.34e-45 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
HJKBDKNK_00267 1.21e-135 - - - L - - - Integrase
HJKBDKNK_00269 5.71e-71 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HJKBDKNK_00270 7.48e-56 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HJKBDKNK_00271 2.71e-103 usp5 - - T - - - universal stress protein
HJKBDKNK_00272 2.7e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HJKBDKNK_00273 5.61e-292 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HJKBDKNK_00274 2.19e-134 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HJKBDKNK_00275 1.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HJKBDKNK_00276 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HJKBDKNK_00277 4.92e-286 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HJKBDKNK_00278 7.7e-227 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
HJKBDKNK_00279 9.06e-186 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HJKBDKNK_00280 9.21e-120 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HJKBDKNK_00281 1.21e-48 - - - - - - - -
HJKBDKNK_00282 1.45e-67 - - - - - - - -
HJKBDKNK_00283 6.14e-259 - - - - - - - -
HJKBDKNK_00284 4.74e-107 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HJKBDKNK_00285 3.4e-176 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HJKBDKNK_00286 5.94e-201 yvgN - - S - - - Aldo keto reductase
HJKBDKNK_00287 1.84e-162 XK27_10500 - - K - - - response regulator
HJKBDKNK_00288 7.47e-234 kinG - - T - - - Histidine kinase-like ATPases
HJKBDKNK_00289 6.81e-172 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00290 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HJKBDKNK_00291 1.64e-200 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HJKBDKNK_00292 1.07e-212 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HJKBDKNK_00293 7.86e-13 - - - K - - - helix_turn_helix, mercury resistance
HJKBDKNK_00294 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJKBDKNK_00295 2.73e-248 - - - EGP - - - Major Facilitator
HJKBDKNK_00296 2.45e-112 ymdB - - S - - - Macro domain protein
HJKBDKNK_00297 9.15e-129 - - - K - - - Helix-turn-helix XRE-family like proteins
HJKBDKNK_00298 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HJKBDKNK_00299 2.02e-62 - - - - - - - -
HJKBDKNK_00300 8.96e-292 - - - S - - - Putative metallopeptidase domain
HJKBDKNK_00301 1.2e-260 - - - S - - - associated with various cellular activities
HJKBDKNK_00302 8.15e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HJKBDKNK_00303 2.01e-84 yeaO - - S - - - Protein of unknown function, DUF488
HJKBDKNK_00305 1.43e-152 yrkL - - S - - - Flavodoxin-like fold
HJKBDKNK_00306 9.17e-70 - - - - - - - -
HJKBDKNK_00308 4.78e-39 - - - S - - - PD-(D/E)XK nuclease family transposase
HJKBDKNK_00309 1.68e-64 - - - - - - - -
HJKBDKNK_00310 4.53e-263 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HJKBDKNK_00311 2.88e-290 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HJKBDKNK_00312 5.41e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HJKBDKNK_00313 2.85e-135 - - - NU - - - mannosyl-glycoprotein
HJKBDKNK_00314 8.04e-184 - - - S - - - Putative ABC-transporter type IV
HJKBDKNK_00315 0.0 - - - S - - - ABC transporter, ATP-binding protein
HJKBDKNK_00317 1.12e-46 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HJKBDKNK_00318 1.78e-232 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HJKBDKNK_00319 1.31e-93 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HJKBDKNK_00320 2.94e-73 cadX - - K ko:K21903 - ko00000,ko03000 Bacterial regulatory protein, arsR family
HJKBDKNK_00321 4.82e-131 cadD - - P - - - Cadmium resistance transporter
HJKBDKNK_00323 1.38e-116 - - - L - - - Integrase
HJKBDKNK_00324 3.37e-27 - - - - - - - -
HJKBDKNK_00325 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HJKBDKNK_00326 1.02e-51 - - - - - - - -
HJKBDKNK_00327 4.71e-112 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HJKBDKNK_00328 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HJKBDKNK_00329 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HJKBDKNK_00330 7.93e-242 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HJKBDKNK_00331 4.3e-96 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HJKBDKNK_00332 3.16e-107 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HJKBDKNK_00333 5.12e-302 yhdP - - S - - - Transporter associated domain
HJKBDKNK_00334 8.05e-198 - - - V - - - (ABC) transporter
HJKBDKNK_00335 9.43e-116 - - - GM - - - epimerase
HJKBDKNK_00336 5.04e-116 - - - K - - - Domain of unknown function (DUF1836)
HJKBDKNK_00337 8.16e-103 yybA - - K - - - Transcriptional regulator
HJKBDKNK_00338 3.53e-169 XK27_07210 - - S - - - B3 4 domain
HJKBDKNK_00339 4.09e-235 XK27_12525 - - S - - - AI-2E family transporter
HJKBDKNK_00340 8.07e-199 - - - G - - - Xylose isomerase domain protein TIM barrel
HJKBDKNK_00341 3.47e-161 - - - - - - - -
HJKBDKNK_00342 2.22e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HJKBDKNK_00343 2.43e-189 - - - K - - - helix_turn_helix, arabinose operon control protein
HJKBDKNK_00344 1.78e-129 pgm1 - - G - - - phosphoglycerate mutase
HJKBDKNK_00345 1.15e-14 - - - P - - - Cadmium resistance transporter
HJKBDKNK_00346 8.82e-71 - - - P - - - Cadmium resistance transporter
HJKBDKNK_00347 1.16e-91 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HJKBDKNK_00348 1.15e-116 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
HJKBDKNK_00349 3.78e-220 cobD 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Aminotransferase class I and II
HJKBDKNK_00350 8.57e-280 cbiA 6.3.5.11, 6.3.5.9 - F ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HJKBDKNK_00351 8.87e-202 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HJKBDKNK_00352 1.06e-138 cbiC 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-8X methylmutase
HJKBDKNK_00353 4.24e-251 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HJKBDKNK_00354 4.23e-118 cbiE 2.1.1.289 - H ko:K03399 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HJKBDKNK_00355 1.45e-108 cbiT 2.1.1.196 - H ko:K02191 ko00860,map00860 ko00000,ko00001,ko01000 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HJKBDKNK_00356 2.55e-168 cbiF 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HJKBDKNK_00357 1.32e-196 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
HJKBDKNK_00358 2.78e-166 cbiH 2.1.1.131 - H ko:K05934 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HJKBDKNK_00359 4.87e-145 cobK 1.3.1.106, 1.3.1.54 - H ko:K05895 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6x reductase CbiJ/CobK
HJKBDKNK_00360 1.94e-248 cobA 2.1.1.107, 4.2.1.75 - H ko:K02303,ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HJKBDKNK_00361 2e-152 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalt chelatase (CbiK)
HJKBDKNK_00362 8.8e-136 cbiL 2.1.1.130, 2.1.1.151 - H ko:K03394 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Tetrapyrrole (Corrin/Porphyrin) Methylases
HJKBDKNK_00363 1.27e-170 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HJKBDKNK_00364 1.04e-64 cbiN - - P ko:K02009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HJKBDKNK_00365 1.72e-143 cbiQ - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HJKBDKNK_00366 5.78e-175 cbiO - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 part of an ABC transporter complex. Responsible for energy coupling to the transport system
HJKBDKNK_00367 0.0 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HJKBDKNK_00368 3.95e-86 cysG 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Putative NAD(P)-binding
HJKBDKNK_00369 7.92e-261 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HJKBDKNK_00370 3.01e-186 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HJKBDKNK_00371 2.03e-225 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Delta-aminolevulinic acid dehydratase
HJKBDKNK_00372 2.88e-309 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-III
HJKBDKNK_00373 6.75e-113 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
HJKBDKNK_00374 1.14e-155 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HJKBDKNK_00375 1.27e-117 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HJKBDKNK_00376 2.19e-140 - - - H - - - Uroporphyrinogen-III synthase
HJKBDKNK_00377 1.14e-208 cobT 2.4.2.21 - F ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HJKBDKNK_00378 7.88e-141 - - - L - - - Transposase and inactivated derivatives IS30 family
HJKBDKNK_00379 6.1e-277 - - - L - - - Integrase core domain
HJKBDKNK_00380 2.25e-39 - - - O - - - Bacterial dnaA protein
HJKBDKNK_00381 3.27e-294 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HJKBDKNK_00382 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HJKBDKNK_00383 1.78e-97 - - - F - - - Nudix hydrolase
HJKBDKNK_00384 8.55e-129 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HJKBDKNK_00385 4.26e-107 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HJKBDKNK_00386 5.45e-35 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HJKBDKNK_00387 5.2e-190 - - - - - - - -
HJKBDKNK_00388 2.91e-51 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HJKBDKNK_00389 7.15e-122 - - - K - - - Transcriptional regulator (TetR family)
HJKBDKNK_00390 4.29e-278 yhgE - - V ko:K01421 - ko00000 domain protein
HJKBDKNK_00391 1.14e-230 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJKBDKNK_00392 6.47e-10 - - - S - - - CsbD-like
HJKBDKNK_00393 5.25e-45 - - - S - - - Transglycosylase associated protein
HJKBDKNK_00394 8.39e-297 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HJKBDKNK_00395 6.69e-162 pgm3 - - G - - - phosphoglycerate mutase
HJKBDKNK_00396 2.31e-148 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HJKBDKNK_00397 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HJKBDKNK_00398 3.89e-49 - - - Q - - - pyridine nucleotide-disulphide oxidoreductase
HJKBDKNK_00399 6.17e-203 - - - EG - - - EamA-like transporter family
HJKBDKNK_00400 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HJKBDKNK_00401 8.32e-226 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HJKBDKNK_00402 1.98e-278 - - - S ko:K07133 - ko00000 cog cog1373
HJKBDKNK_00404 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HJKBDKNK_00409 9.9e-39 - - - L ko:K07484 - ko00000 Transposase IS66 family
HJKBDKNK_00410 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HJKBDKNK_00411 1.55e-95 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HJKBDKNK_00413 1.82e-156 - - - S - - - Fic/DOC family
HJKBDKNK_00414 1.78e-208 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HJKBDKNK_00415 7.71e-81 - - - - - - - -
HJKBDKNK_00416 9.25e-270 yttB - - EGP - - - Major Facilitator
HJKBDKNK_00417 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HJKBDKNK_00418 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HJKBDKNK_00419 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HJKBDKNK_00420 1.73e-128 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HJKBDKNK_00421 3.82e-59 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HJKBDKNK_00422 4.43e-41 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HJKBDKNK_00423 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HJKBDKNK_00424 1.7e-113 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HJKBDKNK_00425 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HJKBDKNK_00426 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HJKBDKNK_00427 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HJKBDKNK_00428 3.29e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HJKBDKNK_00429 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HJKBDKNK_00430 1.29e-259 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HJKBDKNK_00431 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HJKBDKNK_00432 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HJKBDKNK_00433 1.39e-76 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HJKBDKNK_00434 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HJKBDKNK_00435 1.72e-167 jag - - S ko:K06346 - ko00000 R3H domain protein
HJKBDKNK_00436 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HJKBDKNK_00437 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HJKBDKNK_00438 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HJKBDKNK_00439 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HJKBDKNK_00440 4.26e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HJKBDKNK_00441 4.93e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HJKBDKNK_00442 1.58e-19 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
HJKBDKNK_00443 2.99e-64 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
HJKBDKNK_00445 1.37e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
HJKBDKNK_00446 5.84e-194 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HJKBDKNK_00447 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HJKBDKNK_00448 1.15e-25 - - - - - - - -
HJKBDKNK_00449 1.54e-146 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HJKBDKNK_00450 5.69e-147 - - - S - - - Protein of unknown function (DUF421)
HJKBDKNK_00451 3.91e-95 - - - S - - - Protein of unknown function (DUF3290)
HJKBDKNK_00452 8.32e-56 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
HJKBDKNK_00453 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJKBDKNK_00454 1.99e-201 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HJKBDKNK_00455 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HJKBDKNK_00457 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HJKBDKNK_00458 7.36e-291 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HJKBDKNK_00459 3.25e-155 - - - S - - - SNARE associated Golgi protein
HJKBDKNK_00460 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HJKBDKNK_00461 5.16e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HJKBDKNK_00462 4.18e-75 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HJKBDKNK_00463 2.79e-89 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HJKBDKNK_00464 1.82e-186 - - - S - - - DUF218 domain
HJKBDKNK_00465 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HJKBDKNK_00466 2.2e-315 yhdP - - S - - - Transporter associated domain
HJKBDKNK_00467 3.97e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HJKBDKNK_00468 3.23e-306 - - - U - - - Belongs to the major facilitator superfamily
HJKBDKNK_00469 2.24e-96 - - - S - - - UPF0756 membrane protein
HJKBDKNK_00470 9.01e-101 - - - S - - - Cupin domain
HJKBDKNK_00471 1.89e-105 - - - C - - - Flavodoxin
HJKBDKNK_00472 5.26e-202 rlrB - - K - - - LysR substrate binding domain protein
HJKBDKNK_00473 3.75e-212 yvgN - - C - - - Aldo keto reductase
HJKBDKNK_00474 4.3e-52 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HJKBDKNK_00475 9.84e-91 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HJKBDKNK_00476 2.28e-84 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HJKBDKNK_00477 2.15e-121 - - - K - - - Acetyltransferase (GNAT) domain
HJKBDKNK_00478 3.05e-199 - - - S - - - Alpha beta hydrolase
HJKBDKNK_00479 3.44e-201 gspA - - M - - - family 8
HJKBDKNK_00480 9.78e-151 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HJKBDKNK_00481 4.82e-120 - - - - - - - -
HJKBDKNK_00482 3.45e-206 - - - S - - - EDD domain protein, DegV family
HJKBDKNK_00483 5.95e-46 - - - EGP - - - Major Facilitator
HJKBDKNK_00484 2.35e-193 - - - EGP - - - Major Facilitator
HJKBDKNK_00485 2.53e-88 - - - K - - - Transcriptional regulator
HJKBDKNK_00486 1.53e-52 - - - - - - - -
HJKBDKNK_00487 0.0 ydaO - - E - - - amino acid
HJKBDKNK_00488 0.0 - - - E - - - amino acid
HJKBDKNK_00489 7.03e-103 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HJKBDKNK_00490 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HJKBDKNK_00491 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HJKBDKNK_00493 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HJKBDKNK_00494 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HJKBDKNK_00495 4.85e-232 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HJKBDKNK_00496 5.13e-288 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_00497 7.09e-179 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HJKBDKNK_00498 1.48e-176 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HJKBDKNK_00499 8.21e-287 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HJKBDKNK_00500 8.51e-169 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HJKBDKNK_00501 2.77e-249 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HJKBDKNK_00502 1.96e-131 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HJKBDKNK_00503 1.04e-161 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HJKBDKNK_00504 2.35e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HJKBDKNK_00505 4.21e-218 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HJKBDKNK_00506 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HJKBDKNK_00507 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HJKBDKNK_00508 6.81e-173 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HJKBDKNK_00509 1.24e-197 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HJKBDKNK_00510 1.77e-74 yabA - - L - - - Involved in initiation control of chromosome replication
HJKBDKNK_00511 9.74e-231 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HJKBDKNK_00512 1.64e-68 yaaQ - - S - - - Cyclic-di-AMP receptor
HJKBDKNK_00513 3.41e-144 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HJKBDKNK_00514 2.71e-51 - - - S - - - Protein of unknown function (DUF2508)
HJKBDKNK_00515 1.65e-140 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HJKBDKNK_00516 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HJKBDKNK_00517 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HJKBDKNK_00518 9.18e-242 - - - L - - - PFAM Integrase catalytic region
HJKBDKNK_00519 2.33e-165 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HJKBDKNK_00520 3.31e-135 pncA - - Q - - - Isochorismatase family
HJKBDKNK_00521 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HJKBDKNK_00522 8.85e-164 - - - F - - - NUDIX domain
HJKBDKNK_00523 1.27e-115 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HJKBDKNK_00524 8.12e-202 - - - S - - - Phage capsid family
HJKBDKNK_00525 1.29e-50 - - - S - - - Phage gp6-like head-tail connector protein
HJKBDKNK_00526 5.85e-73 - - - S - - - Phage head-tail joining protein
HJKBDKNK_00527 5.17e-72 - - - S - - - Bacteriophage holin family
HJKBDKNK_00528 1.95e-27 - - - - - - - -
HJKBDKNK_00529 4.38e-86 - - - L - - - Recombinase zinc beta ribbon domain
HJKBDKNK_00530 1.86e-148 - - - L - - - Recombinase zinc beta ribbon domain
HJKBDKNK_00531 1.39e-138 - - - L ko:K06400 - ko00000 Recombinase
HJKBDKNK_00532 9.27e-29 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
HJKBDKNK_00533 1.14e-78 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
HJKBDKNK_00534 9.08e-85 ung2 - - L - - - Uracil-DNA glycosylase
HJKBDKNK_00535 2.3e-29 ung2 - - L - - - Uracil-DNA glycosylase
HJKBDKNK_00536 1.68e-146 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HJKBDKNK_00537 3.02e-122 dpsB - - P - - - Belongs to the Dps family
HJKBDKNK_00538 1.35e-46 - - - C - - - Heavy-metal-associated domain
HJKBDKNK_00539 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HJKBDKNK_00540 1.2e-102 - - - - - - - -
HJKBDKNK_00541 6.31e-231 - - - S - - - Domain of unknown function (DUF389)
HJKBDKNK_00542 9.85e-104 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HJKBDKNK_00543 6.77e-80 - - - S - - - Bacteriophage abortive infection AbiH
HJKBDKNK_00544 5.24e-41 - - - S - - - LlaJI restriction endonuclease
HJKBDKNK_00545 3.08e-95 - - - V - - - AAA domain (dynein-related subfamily)
HJKBDKNK_00546 1.27e-150 dcm 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
HJKBDKNK_00547 9.87e-116 - 2.1.1.72 - L ko:K00571,ko:K07319 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HJKBDKNK_00548 3.69e-32 - - - K - - - Cro/C1-type HTH DNA-binding domain
HJKBDKNK_00549 4.02e-147 - - - L - - - Dead deah box helicase domain protein
HJKBDKNK_00550 2.73e-31 - - - S - - - Domain of unknown function (DUF1837)
HJKBDKNK_00552 1.72e-36 - - - - - - - -
HJKBDKNK_00553 6.48e-58 - - - - - - - -
HJKBDKNK_00554 3.06e-262 - - - L - - - Protein of unknown function (DUF2800)
HJKBDKNK_00555 3.85e-128 - - - S - - - Protein of unknown function (DUF2815)
HJKBDKNK_00556 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase
HJKBDKNK_00557 3.43e-88 - - - S - - - Psort location Cytoplasmic, score
HJKBDKNK_00558 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
HJKBDKNK_00559 6.15e-62 - - - S - - - VRR_NUC
HJKBDKNK_00560 0.0 - - - L - - - SNF2 family N-terminal domain
HJKBDKNK_00561 1.45e-112 - - - - - - - -
HJKBDKNK_00562 1.39e-129 - - - - - - - -
HJKBDKNK_00563 9.68e-292 - - - KL - - - DNA methylase
HJKBDKNK_00564 7.91e-126 - - - S - - - Psort location Cytoplasmic, score
HJKBDKNK_00565 8.08e-40 - - - S - - - Domain of unknown function (DUF5049)
HJKBDKNK_00566 0.0 - - - S - - - overlaps another CDS with the same product name
HJKBDKNK_00567 3.61e-305 - - - S - - - Phage portal protein
HJKBDKNK_00568 2.59e-153 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HJKBDKNK_00569 2.02e-269 - - - S - - - Phage capsid family
HJKBDKNK_00570 2.53e-56 - - - S - - - Phage gp6-like head-tail connector protein
HJKBDKNK_00571 8.73e-87 - - - S - - - Phage head-tail joining protein
HJKBDKNK_00572 2.26e-88 - - - S - - - Bacteriophage holin family
HJKBDKNK_00573 1.48e-175 - - - M - - - Glycosyl hydrolases family 25
HJKBDKNK_00574 8.41e-46 - - - - - - - -
HJKBDKNK_00575 0.0 - - - L - - - Recombinase zinc beta ribbon domain
HJKBDKNK_00576 0.0 - - - L - - - Recombinase
HJKBDKNK_00578 5.19e-159 - - - L ko:K07448 - ko00000,ko02048 Mrr N-terminal domain
HJKBDKNK_00579 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HJKBDKNK_00580 1.91e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HJKBDKNK_00581 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HJKBDKNK_00582 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HJKBDKNK_00583 9.59e-67 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HJKBDKNK_00584 1.57e-260 camS - - S - - - sex pheromone
HJKBDKNK_00585 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HJKBDKNK_00586 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HJKBDKNK_00587 4.55e-267 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HJKBDKNK_00588 7.9e-130 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HJKBDKNK_00589 4.18e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HJKBDKNK_00590 2.58e-179 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HJKBDKNK_00591 1.61e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HJKBDKNK_00592 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HJKBDKNK_00593 1.75e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HJKBDKNK_00594 2.89e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HJKBDKNK_00595 2.2e-193 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HJKBDKNK_00596 7.27e-179 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HJKBDKNK_00597 1.15e-82 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HJKBDKNK_00598 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HJKBDKNK_00599 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HJKBDKNK_00600 2.19e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HJKBDKNK_00601 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HJKBDKNK_00602 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HJKBDKNK_00603 6.16e-159 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HJKBDKNK_00604 8.24e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HJKBDKNK_00605 8.6e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HJKBDKNK_00606 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HJKBDKNK_00607 3.45e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HJKBDKNK_00608 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HJKBDKNK_00609 2.14e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HJKBDKNK_00610 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HJKBDKNK_00611 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HJKBDKNK_00612 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HJKBDKNK_00613 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HJKBDKNK_00614 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HJKBDKNK_00615 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HJKBDKNK_00616 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HJKBDKNK_00617 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HJKBDKNK_00618 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HJKBDKNK_00619 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HJKBDKNK_00620 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HJKBDKNK_00621 1.35e-202 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HJKBDKNK_00622 4.22e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HJKBDKNK_00623 6.64e-139 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HJKBDKNK_00624 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HJKBDKNK_00625 1.75e-63 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HJKBDKNK_00626 1.82e-295 - - - L - - - transposase IS116 IS110 IS902 family protein
HJKBDKNK_00627 1.05e-171 - - - L ko:K07487 - ko00000 Transposase
HJKBDKNK_00628 7.44e-82 - - - L ko:K07487 - ko00000 Transposase
HJKBDKNK_00629 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HJKBDKNK_00630 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HJKBDKNK_00631 2.51e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HJKBDKNK_00632 7.25e-140 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HJKBDKNK_00633 1.29e-260 - - - - - - - -
HJKBDKNK_00634 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HJKBDKNK_00635 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HJKBDKNK_00636 8.51e-143 - - - K - - - Bacterial regulatory proteins, tetR family
HJKBDKNK_00637 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HJKBDKNK_00638 2.81e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HJKBDKNK_00639 2.56e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HJKBDKNK_00640 4.55e-197 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HJKBDKNK_00641 0.0 - - - L - - - PLD-like domain
HJKBDKNK_00643 7.12e-228 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HJKBDKNK_00644 2.12e-145 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
HJKBDKNK_00645 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HJKBDKNK_00646 8.99e-258 - - - G - - - Transporter, major facilitator family protein
HJKBDKNK_00647 1.08e-136 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
HJKBDKNK_00648 2.08e-79 yuxO - - Q - - - Thioesterase superfamily
HJKBDKNK_00649 1.16e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HJKBDKNK_00650 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HJKBDKNK_00651 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HJKBDKNK_00652 2.84e-42 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
HJKBDKNK_00653 1.56e-184 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HJKBDKNK_00654 6.75e-305 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HJKBDKNK_00655 1.02e-295 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HJKBDKNK_00656 1.24e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HJKBDKNK_00657 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HJKBDKNK_00658 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
HJKBDKNK_00659 6.4e-204 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HJKBDKNK_00660 7.15e-148 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HJKBDKNK_00661 1.43e-51 - - - S - - - Cytochrome B5
HJKBDKNK_00662 3.3e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HJKBDKNK_00663 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HJKBDKNK_00664 1.54e-191 - - - O - - - Band 7 protein
HJKBDKNK_00665 7.5e-56 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
HJKBDKNK_00666 1.73e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HJKBDKNK_00667 1.73e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HJKBDKNK_00668 4.51e-237 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
HJKBDKNK_00669 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HJKBDKNK_00670 1.83e-21 - - - - - - - -
HJKBDKNK_00672 1.59e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HJKBDKNK_00673 9.5e-238 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HJKBDKNK_00674 7.72e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HJKBDKNK_00675 4.5e-315 steT - - E ko:K03294 - ko00000 amino acid
HJKBDKNK_00676 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HJKBDKNK_00677 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HJKBDKNK_00678 1.03e-19 - - - - - - - -
HJKBDKNK_00679 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HJKBDKNK_00680 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HJKBDKNK_00681 9.93e-115 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HJKBDKNK_00682 4.9e-207 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
HJKBDKNK_00683 1.06e-258 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HJKBDKNK_00684 1.67e-222 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HJKBDKNK_00685 2.76e-215 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HJKBDKNK_00686 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HJKBDKNK_00687 4.31e-176 lutC - - S ko:K00782 - ko00000 LUD domain
HJKBDKNK_00688 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HJKBDKNK_00689 9.42e-234 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HJKBDKNK_00690 9.5e-200 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HJKBDKNK_00691 3.96e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HJKBDKNK_00692 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HJKBDKNK_00693 4.27e-66 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HJKBDKNK_00694 9.13e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HJKBDKNK_00695 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HJKBDKNK_00696 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HJKBDKNK_00697 2.37e-120 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HJKBDKNK_00698 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HJKBDKNK_00699 1.44e-139 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HJKBDKNK_00700 1.18e-308 ctrA - - E ko:K03294 - ko00000 amino acid
HJKBDKNK_00701 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HJKBDKNK_00703 1.1e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HJKBDKNK_00704 0.0 - - - L - - - DNA helicase
HJKBDKNK_00705 4.08e-106 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HJKBDKNK_00706 2.5e-233 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HJKBDKNK_00707 2.26e-242 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HJKBDKNK_00708 3.08e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HJKBDKNK_00709 7.91e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HJKBDKNK_00710 1.05e-225 - - - - - - - -
HJKBDKNK_00711 4.85e-167 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HJKBDKNK_00713 2.25e-206 yunF - - F - - - Protein of unknown function DUF72
HJKBDKNK_00714 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HJKBDKNK_00715 3.58e-198 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HJKBDKNK_00716 8.57e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HJKBDKNK_00717 4.17e-205 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HJKBDKNK_00718 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
HJKBDKNK_00719 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HJKBDKNK_00720 2.75e-213 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HJKBDKNK_00721 1.98e-157 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HJKBDKNK_00722 1.75e-165 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HJKBDKNK_00723 6e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HJKBDKNK_00724 2.14e-312 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HJKBDKNK_00725 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HJKBDKNK_00726 1.19e-98 - - - - - - - -
HJKBDKNK_00727 7.71e-189 yidA - - S - - - hydrolase
HJKBDKNK_00728 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HJKBDKNK_00729 5.02e-190 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HJKBDKNK_00730 3.33e-78 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HJKBDKNK_00731 1.86e-63 ywnA - - K - - - Transcriptional regulator
HJKBDKNK_00732 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HJKBDKNK_00733 2.04e-56 - - - GM - - - NAD dependent epimerase dehydratase family protein
HJKBDKNK_00734 4.75e-78 - - - GM - - - NAD dependent epimerase dehydratase family protein
HJKBDKNK_00735 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HJKBDKNK_00736 2.65e-269 - - - EGP - - - Major Facilitator Superfamily
HJKBDKNK_00737 1.44e-294 - - - - - - - -
HJKBDKNK_00738 1.25e-106 - - - K - - - Transcriptional regulator, HxlR family
HJKBDKNK_00739 2.63e-137 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HJKBDKNK_00740 1.07e-66 ydeP - - K - - - Transcriptional regulator, HxlR family
HJKBDKNK_00741 6.4e-156 - - - GM - - - NmrA-like family
HJKBDKNK_00742 4.78e-95 - - - S ko:K02348 - ko00000 Gnat family
HJKBDKNK_00743 3.33e-39 - - - S - - - Cytochrome B5
HJKBDKNK_00744 1.19e-279 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HJKBDKNK_00746 8.95e-20 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HJKBDKNK_00747 9.04e-152 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HJKBDKNK_00748 4.67e-313 - - - E ko:K03294 - ko00000 amino acid
HJKBDKNK_00749 6.99e-165 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HJKBDKNK_00750 1.09e-63 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HJKBDKNK_00751 3.47e-271 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HJKBDKNK_00753 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HJKBDKNK_00754 1.36e-67 - - - - - - - -
HJKBDKNK_00755 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HJKBDKNK_00756 7.01e-244 - - - E - - - Zinc-binding dehydrogenase
HJKBDKNK_00757 2.52e-111 - - - K - - - transcriptional regulator (TetR family)
HJKBDKNK_00758 9.09e-223 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HJKBDKNK_00759 2.37e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00760 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00761 1.61e-48 - - - - - - - -
HJKBDKNK_00766 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HJKBDKNK_00767 2.49e-43 - - - - - - - -
HJKBDKNK_00768 1.13e-272 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_00769 3.47e-221 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJKBDKNK_00770 6.86e-98 - - - O - - - OsmC-like protein
HJKBDKNK_00771 1.79e-111 - - - K - - - FR47-like protein
HJKBDKNK_00772 3.99e-68 - - - L - - - An automated process has identified a potential problem with this gene model
HJKBDKNK_00775 0.0 - - - S - - - Putative peptidoglycan binding domain
HJKBDKNK_00776 1.82e-44 - - - - - - - -
HJKBDKNK_00777 1.31e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HJKBDKNK_00778 1.14e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HJKBDKNK_00779 1.36e-198 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HJKBDKNK_00780 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HJKBDKNK_00781 2.13e-189 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HJKBDKNK_00782 1.52e-192 - - - E - - - Glyoxalase-like domain
HJKBDKNK_00783 8.4e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HJKBDKNK_00784 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HJKBDKNK_00785 1.76e-122 - - - S - - - reductase
HJKBDKNK_00787 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HJKBDKNK_00788 2.2e-227 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HJKBDKNK_00789 1.08e-112 pgpA - - I - - - Phosphatidylglycerophosphatase A
HJKBDKNK_00791 7.23e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HJKBDKNK_00792 2.52e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HJKBDKNK_00793 1.18e-191 yycI - - S - - - YycH protein
HJKBDKNK_00794 1.89e-312 yycH - - S - - - YycH protein
HJKBDKNK_00795 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HJKBDKNK_00796 1.29e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HJKBDKNK_00799 1.35e-45 - - - - - - - -
HJKBDKNK_00800 2.79e-51 - - - - - - - -
HJKBDKNK_00801 1.65e-37 - - - - - - - -
HJKBDKNK_00802 2.6e-194 - - - G - - - Belongs to the phosphoglycerate mutase family
HJKBDKNK_00803 4.6e-157 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HJKBDKNK_00804 8.28e-135 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HJKBDKNK_00805 2.14e-91 - - - - - - - -
HJKBDKNK_00806 0.0 XK27_00340 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HJKBDKNK_00807 4.61e-133 - - - L - - - nuclease
HJKBDKNK_00808 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HJKBDKNK_00809 1.59e-265 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HJKBDKNK_00810 2.39e-184 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HJKBDKNK_00811 0.0 snf - - KL - - - domain protein
HJKBDKNK_00813 2.74e-50 - - - - ko:K18829 - ko00000,ko02048 -
HJKBDKNK_00814 7.25e-89 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxin-antitoxin system, toxin component, MazF family
HJKBDKNK_00816 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HJKBDKNK_00817 4.41e-218 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HJKBDKNK_00818 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HJKBDKNK_00819 0.0 XK27_08510 - - L - - - Type III restriction protein res subunit
HJKBDKNK_00820 5.47e-102 lacR - - K - - - helix_turn_helix, arabinose operon control protein
HJKBDKNK_00821 3.27e-301 lacP - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HJKBDKNK_00822 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HJKBDKNK_00823 7.21e-20 - - - S - - - NADPH-dependent FMN reductase
HJKBDKNK_00824 8.71e-172 - - - L ko:K07484 - ko00000 Transposase IS66 family
HJKBDKNK_00825 9.71e-64 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HJKBDKNK_00827 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Type I restriction enzyme R protein N terminus (HSDR_N)
HJKBDKNK_00828 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HJKBDKNK_00829 2.02e-145 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HJKBDKNK_00830 3.78e-85 - - - K - - - Putative DNA-binding domain
HJKBDKNK_00835 3.65e-75 - - - L - - - Resolvase, N terminal domain
HJKBDKNK_00838 6.66e-161 - - - L - - - Belongs to the 'phage' integrase family
HJKBDKNK_00841 6.04e-109 - - - - - - - -
HJKBDKNK_00842 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HJKBDKNK_00843 6.21e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HJKBDKNK_00844 3.77e-217 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HJKBDKNK_00845 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HJKBDKNK_00846 1.44e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HJKBDKNK_00847 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HJKBDKNK_00848 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HJKBDKNK_00849 2.4e-73 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HJKBDKNK_00850 4.11e-52 yabO - - J - - - S4 domain protein
HJKBDKNK_00851 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HJKBDKNK_00852 3.25e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HJKBDKNK_00853 2.7e-145 - - - S - - - (CBS) domain
HJKBDKNK_00854 8.04e-186 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HJKBDKNK_00855 1.59e-308 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HJKBDKNK_00856 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HJKBDKNK_00857 1.3e-82 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HJKBDKNK_00858 9.94e-266 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HJKBDKNK_00859 8.96e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HJKBDKNK_00860 4.54e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HJKBDKNK_00861 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HJKBDKNK_00862 9.07e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HJKBDKNK_00863 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HJKBDKNK_00864 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HJKBDKNK_00865 2.73e-70 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HJKBDKNK_00866 1.71e-127 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HJKBDKNK_00867 1.64e-263 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HJKBDKNK_00868 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HJKBDKNK_00869 1.7e-54 - - - - - - - -
HJKBDKNK_00870 3.87e-161 pgm3 - - G - - - phosphoglycerate mutase family
HJKBDKNK_00871 8.49e-44 - - - K - - - Bacterial transcriptional regulator
HJKBDKNK_00872 4.54e-89 - 1.1.1.100, 1.1.1.304, 1.1.1.76 - IQ ko:K00059,ko:K18009 ko00061,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00650,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HJKBDKNK_00873 1.52e-81 - - - S - - - C4-dicarboxylate anaerobic carrier
HJKBDKNK_00874 7.48e-234 - - - S - - - C4-dicarboxylate anaerobic carrier
HJKBDKNK_00875 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HJKBDKNK_00876 5.58e-306 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HJKBDKNK_00877 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HJKBDKNK_00878 3.34e-215 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HJKBDKNK_00879 8.51e-214 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HJKBDKNK_00880 1.08e-168 yceF - - P ko:K05794 - ko00000 membrane
HJKBDKNK_00881 6.46e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HJKBDKNK_00882 1.7e-299 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HJKBDKNK_00883 1.33e-73 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HJKBDKNK_00884 2.98e-123 - - - P - - - Cadmium resistance transporter
HJKBDKNK_00885 5.63e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00886 1.18e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HJKBDKNK_00887 7.44e-232 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HJKBDKNK_00888 1.46e-156 - - - M - - - PFAM NLP P60 protein
HJKBDKNK_00889 2.96e-125 - - - S - - - Protein of unknown function (DUF3278)
HJKBDKNK_00890 5.78e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
HJKBDKNK_00891 2.53e-65 - - - L - - - Integrase
HJKBDKNK_00892 3.36e-18 XK27_09155 - - K - - - Transcriptional
HJKBDKNK_00893 2.78e-118 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HJKBDKNK_00894 3.63e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HJKBDKNK_00895 1.13e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HJKBDKNK_00896 8.5e-218 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HJKBDKNK_00897 2.86e-217 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HJKBDKNK_00898 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HJKBDKNK_00899 1.57e-113 ypmB - - S - - - Protein conserved in bacteria
HJKBDKNK_00900 7.96e-158 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HJKBDKNK_00901 2.32e-206 - - - EG - - - EamA-like transporter family
HJKBDKNK_00902 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HJKBDKNK_00903 2.01e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HJKBDKNK_00904 4.8e-130 ypsA - - S - - - Belongs to the UPF0398 family
HJKBDKNK_00905 3.25e-72 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HJKBDKNK_00906 1.62e-106 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
HJKBDKNK_00907 5.93e-283 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HJKBDKNK_00908 1.55e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HJKBDKNK_00909 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
HJKBDKNK_00910 1.79e-96 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HJKBDKNK_00911 7.97e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HJKBDKNK_00912 2.15e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HJKBDKNK_00913 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HJKBDKNK_00914 0.0 FbpA - - K - - - Fibronectin-binding protein
HJKBDKNK_00915 1.71e-23 - - - - - - - -
HJKBDKNK_00916 1.52e-81 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HJKBDKNK_00917 7.5e-53 - - - S - - - Phage head-tail joining protein
HJKBDKNK_00918 1.64e-89 - - - S - - - Phage gp6-like head-tail connector protein
HJKBDKNK_00919 7.28e-266 - - - S - - - Phage capsid family
HJKBDKNK_00920 3.54e-148 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
HJKBDKNK_00921 2.64e-306 - - - S - - - Phage portal protein
HJKBDKNK_00923 0.0 terL - - S - - - overlaps another CDS with the same product name
HJKBDKNK_00924 1.62e-100 - - - L - - - Phage terminase, small subunit
HJKBDKNK_00925 8.04e-189 - - - L - - - HNH nucleases
HJKBDKNK_00928 1.96e-06 - - - - - - - -
HJKBDKNK_00932 4.82e-103 - - - S - - - Phage transcriptional regulator, ArpU family
HJKBDKNK_00938 1.78e-161 - - - - - - - -
HJKBDKNK_00939 8.03e-92 - - - - - - - -
HJKBDKNK_00941 2.18e-54 - - - S - - - HNH endonuclease
HJKBDKNK_00944 1.23e-175 - - - L - - - Belongs to the 'phage' integrase family
HJKBDKNK_00945 5.46e-111 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HJKBDKNK_00946 1.09e-170 - - - L - - - DnaD domain protein
HJKBDKNK_00951 6.69e-24 - - - - - - - -
HJKBDKNK_00952 3.08e-34 - - - K - - - Helix-turn-helix XRE-family like proteins
HJKBDKNK_00954 3.73e-39 - - - S - - - Short C-terminal domain
HJKBDKNK_00955 1.08e-78 - - - - - - - -
HJKBDKNK_00958 2.6e-29 - - - S - - - Protein of unknown function (DUF4231)
HJKBDKNK_00959 6.75e-91 - - - S - - - MTH538 TIR-like domain (DUF1863)
HJKBDKNK_00960 4.01e-35 - - - - - - - -
HJKBDKNK_00961 2.93e-116 - - - L - - - Belongs to the 'phage' integrase family
HJKBDKNK_00962 2.61e-300 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HJKBDKNK_00963 1.1e-193 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HJKBDKNK_00964 1.27e-159 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HJKBDKNK_00965 7.19e-280 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_00966 1.03e-265 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HJKBDKNK_00967 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HJKBDKNK_00968 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HJKBDKNK_00969 2.14e-234 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HJKBDKNK_00970 1.02e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HJKBDKNK_00971 1.08e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HJKBDKNK_00972 1.66e-77 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HJKBDKNK_00973 2.21e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HJKBDKNK_00974 7.42e-230 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HJKBDKNK_00975 2.54e-219 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HJKBDKNK_00976 3.65e-111 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HJKBDKNK_00977 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HJKBDKNK_00978 1.7e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HJKBDKNK_00979 2.62e-238 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HJKBDKNK_00980 6.71e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HJKBDKNK_00981 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HJKBDKNK_00982 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HJKBDKNK_00983 2.57e-169 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_00984 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HJKBDKNK_00985 3.62e-212 - - - G - - - Phosphotransferase enzyme family
HJKBDKNK_00986 7.65e-101 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HJKBDKNK_00987 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HJKBDKNK_00988 1.94e-68 - - - - - - - -
HJKBDKNK_00989 1.08e-161 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HJKBDKNK_00990 1.89e-228 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HJKBDKNK_00991 3.36e-77 - - - - - - - -
HJKBDKNK_00993 7.92e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HJKBDKNK_00995 2.49e-255 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HJKBDKNK_00996 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HJKBDKNK_00997 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HJKBDKNK_00998 1.81e-272 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HJKBDKNK_00999 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HJKBDKNK_01000 3.69e-114 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HJKBDKNK_01001 7.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HJKBDKNK_01002 1.04e-83 - - - - - - - -
HJKBDKNK_01003 3.13e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HJKBDKNK_01004 1.85e-210 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HJKBDKNK_01005 2.79e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HJKBDKNK_01006 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HJKBDKNK_01007 7.97e-65 ylxQ - - J - - - ribosomal protein
HJKBDKNK_01008 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HJKBDKNK_01009 1.18e-274 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HJKBDKNK_01010 6.36e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HJKBDKNK_01011 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HJKBDKNK_01012 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HJKBDKNK_01013 3.85e-297 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HJKBDKNK_01014 5.83e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HJKBDKNK_01015 1.29e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HJKBDKNK_01016 3.48e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HJKBDKNK_01017 1.72e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HJKBDKNK_01018 1.82e-196 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HJKBDKNK_01019 2.91e-183 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HJKBDKNK_01020 1.62e-230 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJKBDKNK_01021 9.65e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HJKBDKNK_01022 1.62e-179 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HJKBDKNK_01023 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HJKBDKNK_01024 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HJKBDKNK_01025 2.7e-47 ynzC - - S - - - UPF0291 protein
HJKBDKNK_01026 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HJKBDKNK_01027 1.94e-268 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HJKBDKNK_01028 7.21e-164 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HJKBDKNK_01029 7.82e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HJKBDKNK_01030 1.59e-226 - - - - - - - -
HJKBDKNK_01031 2.15e-168 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HJKBDKNK_01032 1.94e-308 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HJKBDKNK_01033 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HJKBDKNK_01034 2.37e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HJKBDKNK_01035 1.08e-247 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HJKBDKNK_01036 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HJKBDKNK_01037 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HJKBDKNK_01038 1.98e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HJKBDKNK_01039 4.5e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HJKBDKNK_01040 4.3e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HJKBDKNK_01041 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HJKBDKNK_01042 2.04e-274 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HJKBDKNK_01043 8.95e-110 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HJKBDKNK_01044 1.22e-127 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HJKBDKNK_01045 2.08e-218 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HJKBDKNK_01046 1.68e-230 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HJKBDKNK_01047 1.36e-30 rhaS4 - - K - - - helix_turn_helix, arabinose operon control protein
HJKBDKNK_01049 2.64e-134 - - - K - - - PFAM GCN5-related N-acetyltransferase
HJKBDKNK_01050 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HJKBDKNK_01051 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HJKBDKNK_01052 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HJKBDKNK_01053 5.18e-222 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HJKBDKNK_01054 3.13e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HJKBDKNK_01055 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HJKBDKNK_01056 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HJKBDKNK_01057 1.76e-154 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HJKBDKNK_01058 5.97e-92 - - - - - - - -
HJKBDKNK_01059 0.0 - 2.4.1.5 GH13 G ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 Glycosyl hydrolase family 70
HJKBDKNK_01060 3.54e-35 - - - S - - - Acyltransferase family
HJKBDKNK_01062 1.42e-59 - - - S - - - Glycosyltransferase like family 2
HJKBDKNK_01063 3.62e-34 - - - S - - - Glycosyltransferase like family 2
HJKBDKNK_01064 1.88e-35 - - - M - - - PFAM Glycosyl transferase family 2
HJKBDKNK_01065 3.36e-35 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HJKBDKNK_01066 1.1e-84 cps2I - - S - - - Psort location CytoplasmicMembrane, score
HJKBDKNK_01068 7.29e-50 - - - M - - - Glycosyltransferase GT-D fold
HJKBDKNK_01069 3.33e-81 wefC - - M - - - Stealth protein CR2, conserved region 2
HJKBDKNK_01070 4.29e-104 - - GT4 G ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like domain
HJKBDKNK_01071 3.33e-62 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
HJKBDKNK_01072 2.12e-140 ywqD - - D - - - Capsular exopolysaccharide family
HJKBDKNK_01073 1.44e-124 epsB - - M - - - biosynthesis protein
HJKBDKNK_01074 5e-136 isp - - L - - - Transposase
HJKBDKNK_01075 1.97e-140 - - - L - - - Transposase
HJKBDKNK_01077 3.78e-109 - - - L - - - Transposase
HJKBDKNK_01078 1.22e-15 - - - L - - - Transposase
HJKBDKNK_01079 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HJKBDKNK_01080 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_01081 3.65e-85 nqo1 - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
HJKBDKNK_01082 3.79e-42 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
HJKBDKNK_01083 4.93e-33 pduN - - CQ ko:K04028 - ko00000 Ethanolamine utilisation protein EutN/carboxysome
HJKBDKNK_01084 9.72e-51 eutP - - E ko:K04029 - ko00000 Ethanolamine utilisation - propanediol utilisation
HJKBDKNK_01085 3.3e-113 eutJ - - E ko:K04024 - ko00000 Hsp70 protein
HJKBDKNK_01086 5.32e-52 pduU - - E ko:K04031 - ko00000 BMC
HJKBDKNK_01087 1.61e-63 - - - E - - - Ethanolamine utilisation protein EutQ
HJKBDKNK_01088 1.17e-194 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HJKBDKNK_01090 0.000241 - 2.5.1.17 - E ko:K04032 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score 8.96
HJKBDKNK_01091 1.23e-43 pduA_2 - - CQ ko:K04027 - ko00000 BMC domain
HJKBDKNK_01092 8.31e-180 eutE 1.2.1.10, 1.2.1.76, 1.2.1.81, 1.2.1.87 - C ko:K00132,ko:K13922,ko:K15515,ko:K18119 ko00620,ko00640,ko00650,ko01100,ko01120,ko01200,map00620,map00640,map00650,map01100,map01120,map01200 ko00000,ko00001,ko01000 acetaldehyde dehydrogenase (acetylating)
HJKBDKNK_01093 3.76e-44 - - - CQ ko:K16927 - ko00000,ko00002,ko02000 Carbon dioxide concentrating mechanism carboxysome shell protein
HJKBDKNK_01094 1.29e-118 eutL - - E ko:K04026 - ko00000 BMC
HJKBDKNK_01095 2.23e-155 eutC 4.3.1.7 - E ko:K03736 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Ethanolamine ammonia-lyase light chain (EutC)
HJKBDKNK_01096 1.66e-279 eutB 4.3.1.7 - E ko:K03735,ko:K16785 ko00564,ko01100,ko02010,map00564,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Ethanolamine ammonia lyase large subunit (EutB)
HJKBDKNK_01097 3.86e-219 eutA - - E ko:K04019 ko00564,ko01100,map00564,map01100 ko00000,ko00001 Ethanolamine utilisation protein EutA
HJKBDKNK_01098 2.25e-177 pduQ - - C - - - Iron-containing alcohol dehydrogenase
HJKBDKNK_01099 1.02e-64 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
HJKBDKNK_01101 6.59e-90 ywiB - - S - - - Domain of unknown function (DUF1934)
HJKBDKNK_01102 2.44e-84 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HJKBDKNK_01103 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HJKBDKNK_01104 1.11e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HJKBDKNK_01105 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HJKBDKNK_01106 2.42e-298 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HJKBDKNK_01107 1.78e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HJKBDKNK_01108 1.18e-159 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HJKBDKNK_01109 0.0 pps 2.7.9.2 - H ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HJKBDKNK_01110 1.05e-191 - - - G - - - Right handed beta helix region
HJKBDKNK_01111 8.28e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HJKBDKNK_01112 5.32e-208 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HJKBDKNK_01113 1.84e-155 - - - G - - - Belongs to the phosphoglycerate mutase family
HJKBDKNK_01114 5.7e-114 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HJKBDKNK_01115 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
HJKBDKNK_01116 3.7e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HJKBDKNK_01117 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HJKBDKNK_01118 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HJKBDKNK_01119 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HJKBDKNK_01120 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HJKBDKNK_01121 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HJKBDKNK_01122 5.09e-208 - - - S - - - Tetratricopeptide repeat
HJKBDKNK_01123 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HJKBDKNK_01124 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HJKBDKNK_01125 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HJKBDKNK_01126 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HJKBDKNK_01127 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
HJKBDKNK_01128 2.44e-20 - - - - - - - -
HJKBDKNK_01129 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HJKBDKNK_01130 8.35e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HJKBDKNK_01131 2.79e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HJKBDKNK_01132 2.9e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HJKBDKNK_01133 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HJKBDKNK_01134 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HJKBDKNK_01135 2.18e-122 - - - - - - - -
HJKBDKNK_01137 5.43e-179 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HJKBDKNK_01138 2.94e-285 - - - G - - - Glycosyl hydrolases family 8
HJKBDKNK_01139 1.17e-204 ydaM - - M - - - Glycosyl transferase family group 2
HJKBDKNK_01141 1.46e-184 - - - - - - - -
HJKBDKNK_01142 6.09e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HJKBDKNK_01143 9.02e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HJKBDKNK_01144 3.83e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HJKBDKNK_01145 3.23e-194 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HJKBDKNK_01146 6.95e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HJKBDKNK_01147 3.98e-168 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
HJKBDKNK_01148 1.51e-21 - - - K - - - Transcriptional regulator, HxlR family
HJKBDKNK_01149 6.97e-240 - - - - - - - -
HJKBDKNK_01150 5.26e-123 - - - K - - - acetyltransferase
HJKBDKNK_01151 0.0 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HJKBDKNK_01152 5.29e-240 - - - - - - - -
HJKBDKNK_01153 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HJKBDKNK_01154 1.54e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HJKBDKNK_01155 3.81e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HJKBDKNK_01156 3.69e-196 yeaE - - S - - - Aldo keto
HJKBDKNK_01157 3.25e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HJKBDKNK_01158 6.91e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HJKBDKNK_01159 7.79e-188 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HJKBDKNK_01160 6.6e-131 - - - M - - - LysM domain protein
HJKBDKNK_01161 0.0 - - - EP - - - Psort location Cytoplasmic, score
HJKBDKNK_01162 1.08e-85 - - - M - - - LysM domain protein
HJKBDKNK_01163 2.05e-200 - - - O - - - Uncharacterized protein family (UPF0051)
HJKBDKNK_01164 1.61e-143 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HJKBDKNK_01165 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HJKBDKNK_01166 1.13e-77 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HJKBDKNK_01167 4.03e-165 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HJKBDKNK_01168 1.59e-30 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HJKBDKNK_01169 2.28e-121 - - - K - - - Acetyltransferase (GNAT) domain
HJKBDKNK_01183 6.48e-167 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HJKBDKNK_01184 1.48e-174 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HJKBDKNK_01185 8.4e-184 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HJKBDKNK_01186 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HJKBDKNK_01187 2.29e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HJKBDKNK_01188 2.08e-96 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HJKBDKNK_01189 6.15e-280 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HJKBDKNK_01190 1.26e-159 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HJKBDKNK_01191 2.72e-194 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HJKBDKNK_01192 1.99e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HJKBDKNK_01193 2.52e-215 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HJKBDKNK_01194 1.94e-100 - - - K - - - Transcriptional regulator, MarR family
HJKBDKNK_01195 1.39e-91 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HJKBDKNK_01197 2.31e-256 xerS - - L - - - Belongs to the 'phage' integrase family
HJKBDKNK_01198 3.1e-116 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
HJKBDKNK_01199 3.63e-120 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
HJKBDKNK_01200 4.69e-200 rssA - - S - - - Phospholipase, patatin family
HJKBDKNK_01201 9.45e-152 - - - L - - - Integrase
HJKBDKNK_01202 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HJKBDKNK_01203 5.75e-114 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HJKBDKNK_01204 3.02e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
HJKBDKNK_01205 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HJKBDKNK_01206 3.29e-298 - - - E - - - amino acid
HJKBDKNK_01207 1.1e-154 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HJKBDKNK_01208 6.02e-305 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HJKBDKNK_01209 2.96e-211 - - - GK - - - ROK family
HJKBDKNK_01210 0.0 fusA1 - - J - - - elongation factor G
HJKBDKNK_01211 7.46e-106 uspA3 - - T - - - universal stress protein
HJKBDKNK_01212 2.02e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HJKBDKNK_01213 1.78e-83 - - - - - - - -
HJKBDKNK_01214 2.31e-11 - - - - - - - -
HJKBDKNK_01215 4.7e-76 - - - - - - - -
HJKBDKNK_01216 1.21e-68 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HJKBDKNK_01217 6.23e-188 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HJKBDKNK_01218 1.34e-196 - - - S - - - haloacid dehalogenase-like hydrolase
HJKBDKNK_01219 8.55e-99 ykuL - - S - - - (CBS) domain
HJKBDKNK_01220 1.65e-120 - - - S ko:K07095 - ko00000 Phosphoesterase
HJKBDKNK_01221 1.72e-135 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HJKBDKNK_01222 3.41e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HJKBDKNK_01223 5.82e-124 yslB - - S - - - Protein of unknown function (DUF2507)
HJKBDKNK_01224 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HJKBDKNK_01225 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HJKBDKNK_01226 7.15e-122 cvpA - - S - - - Colicin V production protein
HJKBDKNK_01227 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
HJKBDKNK_01228 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HJKBDKNK_01229 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
HJKBDKNK_01230 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HJKBDKNK_01231 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HJKBDKNK_01232 2.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HJKBDKNK_01233 1.94e-57 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HJKBDKNK_01234 2.41e-239 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HJKBDKNK_01235 1.36e-242 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HJKBDKNK_01236 5.07e-130 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HJKBDKNK_01237 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HJKBDKNK_01238 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HJKBDKNK_01239 2.29e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HJKBDKNK_01240 2.2e-251 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HJKBDKNK_01241 1.32e-288 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HJKBDKNK_01242 6.73e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HJKBDKNK_01243 3.1e-192 - - - S - - - Helix-turn-helix domain
HJKBDKNK_01244 4.81e-316 ymfH - - S - - - Peptidase M16
HJKBDKNK_01245 7.61e-288 ymfF - - S - - - Peptidase M16 inactive domain protein
HJKBDKNK_01246 7.82e-203 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HJKBDKNK_01247 1.45e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_01248 4.45e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HJKBDKNK_01249 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HJKBDKNK_01250 9e-194 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HJKBDKNK_01251 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HJKBDKNK_01252 4.2e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
HJKBDKNK_01253 9.28e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HJKBDKNK_01254 1.81e-294 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HJKBDKNK_01255 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HJKBDKNK_01256 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HJKBDKNK_01257 5.45e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HJKBDKNK_01258 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HJKBDKNK_01259 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HJKBDKNK_01260 2.37e-291 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HJKBDKNK_01261 7.1e-274 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HJKBDKNK_01262 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HJKBDKNK_01263 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HJKBDKNK_01264 2.92e-80 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HJKBDKNK_01265 2.93e-196 gadC - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HJKBDKNK_01266 0.0 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
HJKBDKNK_01267 1.85e-299 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HJKBDKNK_01268 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HJKBDKNK_01269 4.52e-39 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HJKBDKNK_01270 1.23e-41 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HJKBDKNK_01271 2.14e-234 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HJKBDKNK_01272 9.79e-180 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HJKBDKNK_01273 4.16e-180 - - - S - - - Membrane
HJKBDKNK_01274 2e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HJKBDKNK_01275 9.79e-29 - - - - - - - -
HJKBDKNK_01276 4.1e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HJKBDKNK_01277 1.88e-309 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HJKBDKNK_01278 1.04e-60 - - - - - - - -
HJKBDKNK_01279 1.95e-109 uspA - - T - - - universal stress protein
HJKBDKNK_01280 5.7e-260 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HJKBDKNK_01281 4.45e-81 yvgN - - S - - - Aldo keto reductase
HJKBDKNK_01282 1.67e-106 yvgN - - S - - - Aldo keto reductase
HJKBDKNK_01283 9.78e-119 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HJKBDKNK_01284 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HJKBDKNK_01285 6.65e-179 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HJKBDKNK_01286 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HJKBDKNK_01287 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HJKBDKNK_01288 8.63e-190 - - - K - - - Helix-turn-helix XRE-family like proteins
HJKBDKNK_01289 7.38e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HJKBDKNK_01290 8.55e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HJKBDKNK_01291 9.49e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HJKBDKNK_01292 4.61e-44 - - - S - - - Protein of unknown function (DUF2969)
HJKBDKNK_01293 2.57e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HJKBDKNK_01294 1.66e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HJKBDKNK_01295 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
HJKBDKNK_01296 2.25e-47 - - - T - - - EAL domain
HJKBDKNK_01297 4.69e-165 - - - F - - - glutamine amidotransferase
HJKBDKNK_01298 3.65e-78 - - - - - - - -
HJKBDKNK_01299 4.71e-128 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HJKBDKNK_01300 2.97e-145 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HJKBDKNK_01301 6.02e-190 - - - K - - - Transcriptional regulator
HJKBDKNK_01302 1.99e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HJKBDKNK_01303 3.55e-215 ypuA - - S - - - Protein of unknown function (DUF1002)
HJKBDKNK_01304 1.65e-219 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HJKBDKNK_01305 6.93e-195 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HJKBDKNK_01306 5.78e-153 - - - S - - - Alpha beta hydrolase
HJKBDKNK_01307 1.02e-82 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HJKBDKNK_01308 2.69e-98 - - - S - - - Peptidase propeptide and YPEB domain
HJKBDKNK_01309 1.9e-270 - - - T - - - GHKL domain
HJKBDKNK_01310 3.28e-140 - - - T - - - Transcriptional regulatory protein, C terminal
HJKBDKNK_01311 1.76e-24 - - - H - - - RibD C-terminal domain
HJKBDKNK_01312 8.54e-96 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HJKBDKNK_01313 5.78e-96 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HJKBDKNK_01314 2.58e-56 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HJKBDKNK_01315 7.93e-270 - - - EGP - - - Major Facilitator
HJKBDKNK_01316 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HJKBDKNK_01317 6.96e-29 - - - C - - - Zinc-binding dehydrogenase
HJKBDKNK_01318 1.71e-109 - - - C - - - Zinc-binding dehydrogenase
HJKBDKNK_01319 6.7e-205 - - - - - - - -
HJKBDKNK_01320 1.3e-95 - - - K - - - Transcriptional regulator
HJKBDKNK_01321 5.04e-232 ybcH - - D ko:K06889 - ko00000 Alpha beta
HJKBDKNK_01322 2.59e-68 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HJKBDKNK_01323 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HJKBDKNK_01324 5.35e-70 - - - - - - - -
HJKBDKNK_01325 4.83e-146 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HJKBDKNK_01326 1.15e-314 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_01327 4.26e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HJKBDKNK_01328 1.47e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
HJKBDKNK_01329 1.1e-144 - - - IQ - - - KR domain
HJKBDKNK_01330 5.68e-12 - - - IQ - - - KR domain
HJKBDKNK_01332 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HJKBDKNK_01333 1.04e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HJKBDKNK_01334 1.45e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HJKBDKNK_01335 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HJKBDKNK_01336 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HJKBDKNK_01337 0.0 eriC - - P ko:K03281 - ko00000 chloride
HJKBDKNK_01338 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HJKBDKNK_01339 1.5e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HJKBDKNK_01340 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HJKBDKNK_01341 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HJKBDKNK_01342 9.61e-137 - - - - - - - -
HJKBDKNK_01343 4.35e-173 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HJKBDKNK_01344 2.79e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HJKBDKNK_01345 1.48e-150 - - - S - - - KAP family P-loop domain
HJKBDKNK_01346 0.0 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
HJKBDKNK_01347 1.05e-225 - 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 Adenine specific DNA methylase Mod
HJKBDKNK_01348 2.06e-05 - - - L - - - Resolvase, N terminal domain
HJKBDKNK_01350 2.38e-100 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HJKBDKNK_01354 7.15e-145 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HJKBDKNK_01355 9.7e-162 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HJKBDKNK_01356 1.75e-78 - - - L ko:K07482 - ko00000 transposase and inactivated derivatives, IS30 family
HJKBDKNK_01357 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HJKBDKNK_01358 3.78e-221 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HJKBDKNK_01359 5.24e-33 - - - - - - - -
HJKBDKNK_01360 1.03e-146 - - - - - - - -
HJKBDKNK_01361 3.01e-274 yttB - - EGP - - - Major Facilitator
HJKBDKNK_01362 7.97e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HJKBDKNK_01363 1.41e-88 - - - - - - - -
HJKBDKNK_01364 2.05e-140 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HJKBDKNK_01365 0.0 - - - S - - - Putative peptidoglycan binding domain
HJKBDKNK_01366 8.11e-159 - - - M - - - ErfK YbiS YcfS YnhG
HJKBDKNK_01368 3.45e-125 - - - - - - - -
HJKBDKNK_01369 2.68e-275 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HJKBDKNK_01370 2.45e-105 - - - S - - - Alpha beta hydrolase
HJKBDKNK_01371 2.5e-46 - - - S - - - Alpha beta hydrolase
HJKBDKNK_01372 1.06e-148 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HJKBDKNK_01373 6.92e-130 - - - S - - - Protein of unknown function (DUF1461)
HJKBDKNK_01374 6.76e-170 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HJKBDKNK_01375 2.66e-120 yutD - - S - - - Protein of unknown function (DUF1027)
HJKBDKNK_01376 1.21e-143 - - - S - - - Calcineurin-like phosphoesterase
HJKBDKNK_01377 4.36e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HJKBDKNK_01378 1.15e-182 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HJKBDKNK_01380 3.12e-90 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
HJKBDKNK_01381 1.96e-55 - - - - - - - -
HJKBDKNK_01382 2.12e-102 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HJKBDKNK_01383 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HJKBDKNK_01384 6.11e-233 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HJKBDKNK_01385 1.56e-230 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HJKBDKNK_01386 7.07e-168 yebC - - K - - - Transcriptional regulatory protein
HJKBDKNK_01387 1.23e-173 - - - - - - - -
HJKBDKNK_01388 1.15e-233 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HJKBDKNK_01389 2.97e-267 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HJKBDKNK_01390 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HJKBDKNK_01391 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HJKBDKNK_01392 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HJKBDKNK_01393 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HJKBDKNK_01394 4.56e-219 yagE - - E - - - amino acid
HJKBDKNK_01395 2.14e-148 - - - S - - - HAD hydrolase, family IA, variant
HJKBDKNK_01396 7.54e-122 - - - S - - - PD-(D/E)XK nuclease family transposase
HJKBDKNK_01397 9.55e-44 - - - S - - - PD-(D/E)XK nuclease family transposase
HJKBDKNK_01398 2.41e-233 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HJKBDKNK_01399 5.46e-233 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HJKBDKNK_01400 3.34e-53 - - - K - - - Transcriptional regulator, HxlR family
HJKBDKNK_01401 1.33e-214 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HJKBDKNK_01402 1.01e-179 epsB - - M - - - biosynthesis protein
HJKBDKNK_01403 1.09e-151 ywqD - - D - - - Capsular exopolysaccharide family
HJKBDKNK_01404 2.03e-124 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HJKBDKNK_01405 2.21e-140 - - - M - - - Domain of unknown function (DUF1972)
HJKBDKNK_01407 1.88e-105 - - - S - - - Glycosyltransferase like family 2
HJKBDKNK_01408 3.24e-34 - - - S - - - Glycosyltransferase like family 2
HJKBDKNK_01409 1.75e-69 - - - S - - - Core-2/I-Branching enzyme
HJKBDKNK_01410 1.98e-86 - - - S - - - Bacterial transferase hexapeptide (six repeats)
HJKBDKNK_01411 6.49e-65 - - - - - - - -
HJKBDKNK_01412 2.45e-152 - - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HJKBDKNK_01413 4.65e-39 - - - - - - - -
HJKBDKNK_01414 8.85e-127 - - - K - - - DNA-templated transcription, initiation
HJKBDKNK_01415 3.82e-47 - - - - - - - -
HJKBDKNK_01416 7.27e-112 - - - - - - - -
HJKBDKNK_01417 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HJKBDKNK_01418 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HJKBDKNK_01419 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HJKBDKNK_01420 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HJKBDKNK_01421 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HJKBDKNK_01422 3.25e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HJKBDKNK_01423 5.58e-192 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HJKBDKNK_01424 5.89e-153 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HJKBDKNK_01427 4.73e-170 - - - D - - - transport
HJKBDKNK_01428 5.64e-229 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HJKBDKNK_01429 8.07e-204 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HJKBDKNK_01430 2.23e-184 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Putative cyclase
HJKBDKNK_01431 8.09e-283 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HJKBDKNK_01432 3.03e-166 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HJKBDKNK_01433 3.65e-291 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HJKBDKNK_01434 1.94e-212 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HJKBDKNK_01435 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HJKBDKNK_01436 6.36e-45 - - - S - - - Uncharacterised protein family (UPF0236)
HJKBDKNK_01437 6.34e-166 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HJKBDKNK_01438 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HJKBDKNK_01439 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HJKBDKNK_01440 3.86e-223 ydbI - - K - - - AI-2E family transporter
HJKBDKNK_01441 1.64e-291 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HJKBDKNK_01442 1.3e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HJKBDKNK_01443 7.47e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
HJKBDKNK_01444 1.51e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HJKBDKNK_01445 3.95e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HJKBDKNK_01446 3.93e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HJKBDKNK_01447 4.47e-313 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HJKBDKNK_01448 2.57e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HJKBDKNK_01449 3.6e-130 - - - K - - - LysR substrate binding domain
HJKBDKNK_01450 7.24e-33 - - - K - - - LysR substrate binding domain
HJKBDKNK_01451 4.05e-70 - - - S - - - branched-chain amino acid
HJKBDKNK_01452 9.75e-186 - - - E - - - AzlC protein
HJKBDKNK_01453 3.73e-264 hpk31 - - T - - - Histidine kinase
HJKBDKNK_01454 9.76e-161 vanR - - K - - - response regulator
HJKBDKNK_01455 5.98e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HJKBDKNK_01456 4.58e-216 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HJKBDKNK_01457 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HJKBDKNK_01458 6.43e-300 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HJKBDKNK_01459 4.64e-298 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HJKBDKNK_01460 3.97e-153 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HJKBDKNK_01461 6.3e-175 - - - S - - - Protein of unknown function (DUF1129)
HJKBDKNK_01462 1.75e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HJKBDKNK_01463 2.37e-42 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HJKBDKNK_01464 1.38e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HJKBDKNK_01465 1.38e-178 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HJKBDKNK_01466 3.79e-193 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HJKBDKNK_01467 1.36e-157 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HJKBDKNK_01468 6.22e-210 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HJKBDKNK_01469 8.26e-219 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HJKBDKNK_01470 2.4e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
HJKBDKNK_01471 1.02e-284 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HJKBDKNK_01472 8.05e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_01473 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HJKBDKNK_01474 9.56e-317 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HJKBDKNK_01475 1.67e-45 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HJKBDKNK_01476 1.28e-35 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HJKBDKNK_01477 5.64e-225 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HJKBDKNK_01478 1.27e-259 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HJKBDKNK_01479 4.73e-129 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HJKBDKNK_01481 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HJKBDKNK_01482 1.65e-223 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HJKBDKNK_01483 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HJKBDKNK_01484 1.15e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HJKBDKNK_01485 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HJKBDKNK_01486 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HJKBDKNK_01487 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HJKBDKNK_01488 0.0 sdrF - - M ko:K14194 ko05150,map05150 ko00000,ko00001 protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HJKBDKNK_01489 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HJKBDKNK_01490 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HJKBDKNK_01491 3.48e-94 - - - - - - - -
HJKBDKNK_01492 2.18e-94 - - - K - - - Transcriptional regulator, TetR family
HJKBDKNK_01493 2.53e-17 - - - K - - - Transcriptional regulator, TetR family
HJKBDKNK_01494 8.95e-18 - - - E - - - amino acid
HJKBDKNK_01496 4.65e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HJKBDKNK_01497 5.46e-118 - - - - - - - -
HJKBDKNK_01498 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HJKBDKNK_01499 2.95e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HJKBDKNK_01500 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HJKBDKNK_01501 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
HJKBDKNK_01502 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HJKBDKNK_01503 1.8e-215 - - - C - - - Aldo keto reductase
HJKBDKNK_01504 6.13e-175 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HJKBDKNK_01505 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HJKBDKNK_01506 1.44e-274 - - - P - - - Voltage gated chloride channel
HJKBDKNK_01507 7.94e-290 sptS - - T - - - Histidine kinase
HJKBDKNK_01508 3.15e-153 dltr - - K - - - response regulator
HJKBDKNK_01509 1.02e-111 - - - T - - - Region found in RelA / SpoT proteins
HJKBDKNK_01510 3.6e-135 - - - L ko:K07497 - ko00000 hmm pf00665
HJKBDKNK_01511 1.66e-277 - - - S - - - amidohydrolase
HJKBDKNK_01512 0.0 - - - K - - - Aminotransferase class I and II
HJKBDKNK_01513 4.42e-153 azlC - - E - - - azaleucine resistance protein AzlC
HJKBDKNK_01514 1.58e-66 azlD - - E - - - Branched-chain amino acid transport
HJKBDKNK_01515 1.62e-139 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HJKBDKNK_01517 1.52e-150 - - - S - - - GyrI-like small molecule binding domain
HJKBDKNK_01518 1.23e-133 - - - S ko:K07507 - ko00000,ko02000 MgtC family
HJKBDKNK_01519 8.7e-123 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HJKBDKNK_01520 6.75e-246 flp - - V - - - Beta-lactamase
HJKBDKNK_01521 9.29e-220 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HJKBDKNK_01522 2.07e-196 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HJKBDKNK_01523 7.45e-150 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HJKBDKNK_01524 3.29e-146 yjbH - - Q - - - Thioredoxin
HJKBDKNK_01525 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HJKBDKNK_01526 2.68e-252 coiA - - S ko:K06198 - ko00000 Competence protein
HJKBDKNK_01527 3.67e-153 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HJKBDKNK_01528 2.87e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HJKBDKNK_01529 5.33e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HJKBDKNK_01530 5.75e-52 - - - S - - - Cytochrome B5
HJKBDKNK_01531 1.52e-178 - - - L - - - PFAM Integrase catalytic region
HJKBDKNK_01532 3.7e-19 - - - - - - - -
HJKBDKNK_01533 1.15e-262 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HJKBDKNK_01534 2.1e-117 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HJKBDKNK_01535 1.28e-37 - - - K - - - PFAM GCN5-related N-acetyltransferase
HJKBDKNK_01536 5.69e-105 - - - - - - - -
HJKBDKNK_01537 1.57e-161 - - - M - - - Lysin motif
HJKBDKNK_01538 3.41e-144 - - - I - - - Acid phosphatase homologues
HJKBDKNK_01539 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HJKBDKNK_01540 6.03e-183 - - - L - - - PFAM transposase IS116 IS110 IS902
HJKBDKNK_01541 1.61e-291 - - - P - - - Chloride transporter, ClC family
HJKBDKNK_01542 5.67e-53 - - - S - - - Protein of unknown function (DUF1797)
HJKBDKNK_01543 5.39e-228 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HJKBDKNK_01544 7.98e-253 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HJKBDKNK_01545 5.39e-292 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HJKBDKNK_01546 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HJKBDKNK_01547 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HJKBDKNK_01548 6.77e-28 - - - S - - - Phage derived protein Gp49-like (DUF891)
HJKBDKNK_01549 2.05e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
HJKBDKNK_01550 1.77e-209 - - - I - - - alpha/beta hydrolase fold
HJKBDKNK_01551 4.14e-146 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HJKBDKNK_01552 2.14e-71 - - - - - - - -
HJKBDKNK_01553 5.03e-71 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HJKBDKNK_01554 2.71e-62 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HJKBDKNK_01555 3.33e-140 - - - F ko:K10974 - ko00000,ko02000 cytosine purines uracil thiamine allantoin
HJKBDKNK_01556 2.79e-146 - - - S ko:K09703 - ko00000 Protein of unknown function (DUF917)
HJKBDKNK_01557 2.6e-217 apc3 - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
HJKBDKNK_01558 3.37e-71 - - - L - - - Helix-turn-helix domain
HJKBDKNK_01559 1.44e-157 - - - O - - - Zinc-dependent metalloprotease
HJKBDKNK_01560 3.82e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HJKBDKNK_01561 1.84e-203 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HJKBDKNK_01563 1.2e-205 - - - J - - - Methyltransferase
HJKBDKNK_01564 1.03e-121 ywlG - - S - - - Belongs to the UPF0340 family
HJKBDKNK_01565 1.14e-64 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
HJKBDKNK_01566 2.74e-50 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
HJKBDKNK_01567 1.21e-251 - - - EGP - - - Major Facilitator
HJKBDKNK_01568 2.76e-221 - - - - - - - -
HJKBDKNK_01569 9.01e-95 - - - - - - - -
HJKBDKNK_01570 1.26e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HJKBDKNK_01571 3.22e-189 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HJKBDKNK_01572 1.85e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HJKBDKNK_01573 7.03e-33 - - - - - - - -
HJKBDKNK_01574 7.96e-133 - - - V - - - VanZ like family
HJKBDKNK_01575 2.01e-302 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HJKBDKNK_01576 1.46e-110 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HJKBDKNK_01577 0.0 - - - EGP - - - Major Facilitator
HJKBDKNK_01578 1.82e-120 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HJKBDKNK_01579 6.66e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HJKBDKNK_01580 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HJKBDKNK_01581 2.94e-55 - - - - - - - -
HJKBDKNK_01582 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HJKBDKNK_01583 1.38e-193 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HJKBDKNK_01584 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HJKBDKNK_01585 2.18e-112 - - - T - - - Belongs to the universal stress protein A family
HJKBDKNK_01586 2.33e-224 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HJKBDKNK_01587 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
HJKBDKNK_01588 3.6e-145 - - - - - - - -
HJKBDKNK_01589 1.25e-238 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HJKBDKNK_01590 4.88e-209 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJKBDKNK_01591 1.78e-42 - - - - - - - -
HJKBDKNK_01592 8.99e-141 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HJKBDKNK_01593 9.17e-59 - - - - - - - -
HJKBDKNK_01595 5.19e-90 - - - - - - - -
HJKBDKNK_01596 8.28e-73 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HJKBDKNK_01597 1.78e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HJKBDKNK_01598 1.94e-135 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HJKBDKNK_01599 5.27e-281 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HJKBDKNK_01600 2.85e-134 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HJKBDKNK_01601 6.78e-270 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HJKBDKNK_01602 1.88e-60 - - - - - - - -
HJKBDKNK_01603 2.47e-53 - - - - - - - -
HJKBDKNK_01605 1.51e-210 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HJKBDKNK_01606 6.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HJKBDKNK_01607 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HJKBDKNK_01608 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HJKBDKNK_01609 2.42e-64 yheA - - S - - - Belongs to the UPF0342 family
HJKBDKNK_01610 3.88e-284 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HJKBDKNK_01611 0.0 yhaN - - L - - - AAA domain
HJKBDKNK_01612 4.08e-176 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HJKBDKNK_01614 4.99e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HJKBDKNK_01615 3.83e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_01616 3.29e-279 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HJKBDKNK_01617 1.85e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HJKBDKNK_01618 4.37e-23 - - - S - - - YSIRK type signal peptide
HJKBDKNK_01619 1.79e-18 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
HJKBDKNK_01620 5.11e-17 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
HJKBDKNK_01621 4.35e-76 - 2.1.1.72, 3.1.21.3 AA10,CBM73 M ko:K01154,ko:K02014,ko:K03933,ko:K07316 - ko00000,ko01000,ko02000,ko02048 domain protein
HJKBDKNK_01622 1.59e-14 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HJKBDKNK_01623 5.37e-74 - - - S - - - Small secreted protein
HJKBDKNK_01624 1.64e-72 ytpP - - CO - - - Thioredoxin
HJKBDKNK_01625 3.43e-154 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HJKBDKNK_01626 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HJKBDKNK_01627 6.48e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HJKBDKNK_01628 7.09e-119 - - - S - - - Protein of unknown function (DUF1275)
HJKBDKNK_01629 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HJKBDKNK_01630 1.77e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HJKBDKNK_01631 1.9e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HJKBDKNK_01632 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HJKBDKNK_01633 1.57e-297 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HJKBDKNK_01634 8.6e-222 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HJKBDKNK_01635 1.07e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HJKBDKNK_01636 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HJKBDKNK_01637 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HJKBDKNK_01638 6.39e-124 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HJKBDKNK_01639 7.72e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HJKBDKNK_01640 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HJKBDKNK_01641 2.72e-155 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HJKBDKNK_01642 1.92e-141 yqeK - - H - - - Hydrolase, HD family
HJKBDKNK_01643 2.22e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HJKBDKNK_01644 5.88e-175 yqeM - - Q - - - Methyltransferase
HJKBDKNK_01645 1.48e-268 ylbM - - S - - - Belongs to the UPF0348 family
HJKBDKNK_01646 2.89e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HJKBDKNK_01647 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HJKBDKNK_01648 9.72e-156 csrR - - K - - - response regulator
HJKBDKNK_01649 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HJKBDKNK_01650 0.0 potE - - E - - - Amino Acid
HJKBDKNK_01651 1.51e-297 - - - V - - - MatE
HJKBDKNK_01652 2.53e-88 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HJKBDKNK_01653 3.89e-215 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HJKBDKNK_01654 4.22e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HJKBDKNK_01655 1.57e-185 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HJKBDKNK_01656 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HJKBDKNK_01657 5.79e-78 yodB - - K - - - Transcriptional regulator, HxlR family
HJKBDKNK_01658 6.06e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HJKBDKNK_01659 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HJKBDKNK_01660 3.29e-146 - - - M - - - PFAM NLP P60 protein
HJKBDKNK_01661 2.8e-150 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HJKBDKNK_01662 3.52e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HJKBDKNK_01663 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HJKBDKNK_01664 4.13e-186 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HJKBDKNK_01665 7.65e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HJKBDKNK_01666 2.33e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HJKBDKNK_01667 1.52e-24 - - - S - - - ECF transporter, substrate-specific component
HJKBDKNK_01668 2.03e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HJKBDKNK_01669 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HJKBDKNK_01670 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HJKBDKNK_01671 2.65e-102 - - - S - - - Psort location Cytoplasmic, score
HJKBDKNK_01672 2.91e-110 - - - S - - - Short repeat of unknown function (DUF308)
HJKBDKNK_01673 1e-109 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
HJKBDKNK_01674 1.01e-231 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HJKBDKNK_01675 1.32e-56 - - - K - - - helix_turn_helix, arabinose operon control protein
HJKBDKNK_01695 0.0 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HJKBDKNK_01696 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HJKBDKNK_01697 8e-39 - - - - - - - -
HJKBDKNK_01698 4.81e-22 - - - - - - - -
HJKBDKNK_01699 1.52e-66 - - - - - - - -
HJKBDKNK_01700 4.88e-42 - - - - - - - -
HJKBDKNK_01701 2.13e-88 yneR - - S - - - Belongs to the HesB IscA family
HJKBDKNK_01702 0.0 - - - S - - - membrane
HJKBDKNK_01703 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HJKBDKNK_01704 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HJKBDKNK_01705 8e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HJKBDKNK_01706 7.32e-99 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HJKBDKNK_01707 1.76e-26 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HJKBDKNK_01708 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HJKBDKNK_01709 1.02e-234 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HJKBDKNK_01710 7.66e-88 yqhL - - P - - - Rhodanese-like protein
HJKBDKNK_01711 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
HJKBDKNK_01712 1.96e-224 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HJKBDKNK_01713 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HJKBDKNK_01714 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HJKBDKNK_01715 4.61e-23 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_01716 5.94e-70 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_01717 5.74e-40 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_01718 5.49e-52 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HJKBDKNK_01719 1.28e-18 - - - - - - - -
HJKBDKNK_01720 5.49e-129 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HJKBDKNK_01721 1.08e-67 yitW - - S - - - Iron-sulfur cluster assembly protein
HJKBDKNK_01722 8.07e-202 - - - - - - - -
HJKBDKNK_01723 3.38e-229 - - - - - - - -
HJKBDKNK_01724 1.85e-110 - - - S - - - Protein conserved in bacteria
HJKBDKNK_01728 3.3e-145 - - - K - - - Transcriptional regulator
HJKBDKNK_01729 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HJKBDKNK_01730 8.44e-71 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HJKBDKNK_01731 5.93e-60 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HJKBDKNK_01732 2.05e-165 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HJKBDKNK_01733 1.44e-254 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HJKBDKNK_01734 2.87e-146 - - - J - - - 2'-5' RNA ligase superfamily
HJKBDKNK_01735 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HJKBDKNK_01736 4.34e-90 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HJKBDKNK_01737 1.09e-190 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HJKBDKNK_01738 3.95e-280 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HJKBDKNK_01739 1.15e-57 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HJKBDKNK_01740 5.03e-198 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HJKBDKNK_01741 6.61e-190 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HJKBDKNK_01742 1.11e-100 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HJKBDKNK_01743 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HJKBDKNK_01744 8.66e-70 - - - - - - - -
HJKBDKNK_01745 3.59e-147 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HJKBDKNK_01746 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HJKBDKNK_01747 8.76e-264 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HJKBDKNK_01748 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HJKBDKNK_01749 1.43e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HJKBDKNK_01750 1.98e-314 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HJKBDKNK_01751 1.17e-165 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HJKBDKNK_01752 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HJKBDKNK_01753 1.15e-206 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HJKBDKNK_01754 1.06e-149 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HJKBDKNK_01755 4.7e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HJKBDKNK_01756 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HJKBDKNK_01757 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
HJKBDKNK_01758 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HJKBDKNK_01759 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HJKBDKNK_01760 7.82e-240 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HJKBDKNK_01761 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HJKBDKNK_01762 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HJKBDKNK_01763 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HJKBDKNK_01764 4.05e-258 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HJKBDKNK_01765 4.23e-76 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HJKBDKNK_01766 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HJKBDKNK_01767 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HJKBDKNK_01768 5.32e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HJKBDKNK_01769 1.79e-117 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HJKBDKNK_01770 2.22e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HJKBDKNK_01771 0.0 - - - E ko:K03294 - ko00000 amino acid
HJKBDKNK_01772 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HJKBDKNK_01773 8.66e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
HJKBDKNK_01774 5.32e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HJKBDKNK_01775 3.56e-18 - - - - - - - -
HJKBDKNK_01776 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HJKBDKNK_01777 3.99e-143 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HJKBDKNK_01778 7.44e-51 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HJKBDKNK_01779 6.95e-59 - - - S - - - CRISPR-associated protein (Cas_Csn2)
HJKBDKNK_01780 3.18e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HJKBDKNK_01781 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HJKBDKNK_01782 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HJKBDKNK_01783 4.04e-46 - - - L ko:K07484 - ko00000 Transposase IS66 family
HJKBDKNK_01785 3.75e-45 - - - L ko:K07491 - ko00000 Transposase IS200 like
HJKBDKNK_01786 1.61e-231 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HJKBDKNK_01787 1.22e-50 - - - M - - - LPXTG-motif cell wall anchor domain protein
HJKBDKNK_01788 3.07e-303 - - - L - - - Transposase
HJKBDKNK_01789 8.21e-223 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HJKBDKNK_01790 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HJKBDKNK_01791 1.37e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HJKBDKNK_01792 4.64e-151 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HJKBDKNK_01793 3.1e-113 - - - Q - - - Methyltransferase
HJKBDKNK_01794 2.2e-292 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HJKBDKNK_01795 1.56e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HJKBDKNK_01796 4.58e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HJKBDKNK_01797 1.44e-121 - - - S - - - NADPH-dependent FMN reductase
HJKBDKNK_01798 2.77e-228 - - - S - - - Conserved hypothetical protein 698
HJKBDKNK_01799 1.02e-171 - - - I - - - alpha/beta hydrolase fold
HJKBDKNK_01800 6.14e-39 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HJKBDKNK_01801 7.42e-118 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HJKBDKNK_01802 1.56e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HJKBDKNK_01803 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HJKBDKNK_01804 0.0 arcT - - E - - - Dipeptidase
HJKBDKNK_01805 1.09e-275 - - - EGP - - - Transporter, major facilitator family protein
HJKBDKNK_01806 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
HJKBDKNK_01807 1.37e-178 - - - V - - - Beta-lactamase enzyme family
HJKBDKNK_01808 2.68e-292 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HJKBDKNK_01809 1.42e-92 - - - - - - - -
HJKBDKNK_01810 1.18e-251 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HJKBDKNK_01811 2.33e-29 - - - - - - - -
HJKBDKNK_01812 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HJKBDKNK_01813 5.79e-211 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HJKBDKNK_01814 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
HJKBDKNK_01815 7.79e-263 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
HJKBDKNK_01816 6.76e-143 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HJKBDKNK_01817 1.44e-202 mleR - - K - - - LysR family
HJKBDKNK_01818 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HJKBDKNK_01819 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HJKBDKNK_01820 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HJKBDKNK_01821 1.52e-164 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HJKBDKNK_01822 1.77e-281 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HJKBDKNK_01823 9.08e-158 citR - - K - - - sugar-binding domain protein
HJKBDKNK_01824 8.11e-224 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HJKBDKNK_01825 2.31e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HJKBDKNK_01826 2.56e-56 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HJKBDKNK_01827 3.29e-204 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HJKBDKNK_01828 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HJKBDKNK_01829 8.96e-193 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HJKBDKNK_01830 1.87e-145 - - - I - - - Alpha/beta hydrolase family
HJKBDKNK_01831 3.43e-203 - - - K - - - LysR family
HJKBDKNK_01832 0.0 - - - S - - - Putative threonine/serine exporter
HJKBDKNK_01833 1.1e-151 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HJKBDKNK_01834 0.0 qacA - - EGP - - - Major Facilitator
HJKBDKNK_01835 6.45e-240 - - - I - - - Alpha beta
HJKBDKNK_01836 4.41e-131 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HJKBDKNK_01837 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HJKBDKNK_01839 3.21e-210 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HJKBDKNK_01840 1.08e-159 - - - S - - - Domain of unknown function (DUF4811)
HJKBDKNK_01841 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HJKBDKNK_01842 4.39e-97 - - - K - - - MerR HTH family regulatory protein
HJKBDKNK_01843 8.46e-77 - - - - - - - -
HJKBDKNK_01844 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HJKBDKNK_01845 8.11e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HJKBDKNK_01846 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HJKBDKNK_01847 5.24e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HJKBDKNK_01848 3.85e-195 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HJKBDKNK_01849 1.39e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_01850 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
HJKBDKNK_01851 4.51e-140 - - - S - - - VIT family
HJKBDKNK_01852 2.99e-151 - - - S - - - membrane
HJKBDKNK_01853 3.18e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HJKBDKNK_01854 3.16e-159 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HJKBDKNK_01855 2.54e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HJKBDKNK_01856 1.16e-163 - - - S - - - Putative threonine/serine exporter
HJKBDKNK_01857 8.68e-106 - - - S - - - Threonine/Serine exporter, ThrE
HJKBDKNK_01858 7.68e-151 - - - I - - - phosphatase
HJKBDKNK_01859 1.69e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HJKBDKNK_01860 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HJKBDKNK_01861 3.04e-147 dgk2 - - F - - - deoxynucleoside kinase
HJKBDKNK_01867 2.11e-192 - - - L - - - PFAM Integrase catalytic region
HJKBDKNK_01868 1.32e-121 - - - L ko:K07484 - ko00000 Transposase IS66 family
HJKBDKNK_01873 1.49e-129 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HJKBDKNK_01874 9.26e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HJKBDKNK_01875 1.46e-112 - - - K - - - Acetyltransferase (GNAT) domain
HJKBDKNK_01876 1.45e-98 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HJKBDKNK_01877 3.7e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HJKBDKNK_01878 5.56e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HJKBDKNK_01879 1.78e-211 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HJKBDKNK_01880 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HJKBDKNK_01881 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HJKBDKNK_01882 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HJKBDKNK_01883 5.7e-165 ybbR - - S - - - YbbR-like protein
HJKBDKNK_01884 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HJKBDKNK_01885 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HJKBDKNK_01886 3e-69 - - - - - - - -
HJKBDKNK_01887 0.0 oatA - - I - - - Acyltransferase
HJKBDKNK_01888 6.2e-103 - - - K - - - Transcriptional regulator
HJKBDKNK_01889 5.46e-191 - - - S - - - Cof-like hydrolase
HJKBDKNK_01890 6.22e-107 lytE - - M - - - Lysin motif
HJKBDKNK_01892 4e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HJKBDKNK_01893 0.0 yclK - - T - - - Histidine kinase
HJKBDKNK_01894 2.14e-197 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HJKBDKNK_01895 1.16e-142 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HJKBDKNK_01896 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HJKBDKNK_01897 1.56e-35 - - - - - - - -
HJKBDKNK_01898 1.19e-41 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
HJKBDKNK_01899 2.61e-199 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HJKBDKNK_01900 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HJKBDKNK_01901 9.27e-220 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HJKBDKNK_01902 1.51e-206 - - - EG - - - EamA-like transporter family
HJKBDKNK_01903 4.95e-134 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HJKBDKNK_01904 6.24e-71 - - - S - - - Cupredoxin-like domain
HJKBDKNK_01905 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HJKBDKNK_01906 7.13e-110 - - - - - - - -
HJKBDKNK_01908 3.54e-73 - - - - - - - -
HJKBDKNK_01909 3.72e-48 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HJKBDKNK_01910 2.91e-98 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HJKBDKNK_01911 5.75e-124 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HJKBDKNK_01913 1.22e-72 - - - - - - - -
HJKBDKNK_01923 1.08e-06 - - - S - - - Helix-turn-helix domain
HJKBDKNK_01924 1.5e-56 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HJKBDKNK_01925 3.19e-36 - - - - - - - -
HJKBDKNK_01928 1.75e-169 int2 - - L - - - Belongs to the 'phage' integrase family
HJKBDKNK_01929 1.15e-135 - - - - - - - -
HJKBDKNK_01930 6.45e-160 - - - M - - - domain protein
HJKBDKNK_01931 4.41e-176 - - - M - - - domain protein
HJKBDKNK_01932 7.71e-267 - - - M - - - domain protein
HJKBDKNK_01933 2.14e-65 - - - - - - - -
HJKBDKNK_01934 1.02e-233 ampC - - V - - - Beta-lactamase
HJKBDKNK_01935 4.88e-302 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HJKBDKNK_01936 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HJKBDKNK_01937 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HJKBDKNK_01938 1.32e-295 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
HJKBDKNK_01939 4e-172 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HJKBDKNK_01940 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
HJKBDKNK_01941 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HJKBDKNK_01942 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HJKBDKNK_01943 1.73e-213 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HJKBDKNK_01944 6.29e-250 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HJKBDKNK_01945 3.36e-289 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HJKBDKNK_01946 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HJKBDKNK_01947 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HJKBDKNK_01948 6.71e-246 yibE - - S - - - overlaps another CDS with the same product name
HJKBDKNK_01949 1.41e-167 yibF - - S - - - overlaps another CDS with the same product name
HJKBDKNK_01950 9.76e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HJKBDKNK_01951 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HJKBDKNK_01952 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HJKBDKNK_01953 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HJKBDKNK_01954 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HJKBDKNK_01955 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HJKBDKNK_01956 7.51e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HJKBDKNK_01957 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HJKBDKNK_01958 2.11e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HJKBDKNK_01960 2.21e-87 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HJKBDKNK_01962 7.96e-65 - - - L - - - PFAM Integrase catalytic region
HJKBDKNK_01963 9.12e-147 - - - - - - - -
HJKBDKNK_01965 8.23e-28 - - - - - - - -
HJKBDKNK_01966 0.0 - - - L - - - Phage tail tape measure protein TP901
HJKBDKNK_01967 1.22e-173 - - - S - - - Phage tail protein
HJKBDKNK_01968 8.11e-276 spoIIQ - - M ko:K06386 - ko00000 Peptidase family M23
HJKBDKNK_01970 8.29e-82 - - - S - - - Calcineurin-like phosphoesterase
HJKBDKNK_01972 1.6e-39 - - - S - - - COG5546 Small integral membrane protein
HJKBDKNK_01973 5.47e-178 - - - M - - - Glycosyl hydrolases family 25
HJKBDKNK_01975 3.79e-40 - - - S - - - Protein of unknown function (DUF2929)
HJKBDKNK_01976 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HJKBDKNK_01977 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HJKBDKNK_01978 1.47e-212 yitL - - S ko:K00243 - ko00000 S1 domain
HJKBDKNK_01979 9.16e-209 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HJKBDKNK_01980 5.87e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HJKBDKNK_01981 9.25e-176 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HJKBDKNK_01982 5.49e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HJKBDKNK_01983 3.01e-164 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HJKBDKNK_01984 8.52e-130 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HJKBDKNK_01985 1.43e-250 - - - S - - - Helix-turn-helix domain
HJKBDKNK_01986 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HJKBDKNK_01987 1.04e-69 - - - M - - - Lysin motif
HJKBDKNK_01988 1.27e-151 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HJKBDKNK_01989 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HJKBDKNK_01990 9.51e-317 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HJKBDKNK_01991 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HJKBDKNK_01992 2.61e-298 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HJKBDKNK_01993 7.84e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HJKBDKNK_01994 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HJKBDKNK_01995 1.41e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HJKBDKNK_01996 2.78e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HJKBDKNK_01997 1.23e-142 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HJKBDKNK_01998 3.69e-195 WQ51_01275 - - S - - - EDD domain protein, DegV family
HJKBDKNK_01999 7.3e-216 - - - E - - - lipolytic protein G-D-S-L family
HJKBDKNK_02000 3.33e-140 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HJKBDKNK_02001 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
HJKBDKNK_02002 1.71e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HJKBDKNK_02003 5.03e-181 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HJKBDKNK_02004 1.07e-204 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HJKBDKNK_02005 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HJKBDKNK_02006 3.08e-209 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HJKBDKNK_02007 1.23e-135 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HJKBDKNK_02008 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HJKBDKNK_02009 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HJKBDKNK_02010 1.02e-103 - - - F - - - NUDIX domain
HJKBDKNK_02011 7.36e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HJKBDKNK_02012 2.49e-87 - - - S - - - Belongs to the HesB IscA family
HJKBDKNK_02013 2.16e-64 - - - - - - - -
HJKBDKNK_02015 8.23e-112 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HJKBDKNK_02016 3.7e-79 asp1 - - S - - - Asp23 family, cell envelope-related function
HJKBDKNK_02017 6.23e-35 - - - - - - - -
HJKBDKNK_02018 2.58e-121 - - - - - - - -
HJKBDKNK_02019 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HJKBDKNK_02020 3.78e-230 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HJKBDKNK_02021 1.55e-294 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HJKBDKNK_02022 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HJKBDKNK_02023 2.93e-125 - - - K - - - Acetyltransferase (GNAT) domain
HJKBDKNK_02024 3.8e-63 - - - - - - - -
HJKBDKNK_02025 1.81e-41 - - - - - - - -
HJKBDKNK_02026 7.29e-60 - - - - - - - -
HJKBDKNK_02027 4.03e-98 - - - S - - - Protein of unknown function (DUF805)
HJKBDKNK_02029 1.57e-19 - - - IQ - - - KR domain
HJKBDKNK_02030 2.19e-70 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
HJKBDKNK_02031 2.35e-215 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HJKBDKNK_02032 4.5e-18 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HJKBDKNK_02033 4.07e-118 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)