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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
KOIEMPIK_00003	4.22e-86	-	-	-	L	-	-	-	C-5 cytosine-specific DNA methylase
KOIEMPIK_00004	4.42e-42	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
KOIEMPIK_00005	2.71e-85	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
KOIEMPIK_00008	1.83e-21	-	-	-	-	-	-	-	-
KOIEMPIK_00009	3.19e-95	-	-	-	L	-	-	-	HNH nucleases
KOIEMPIK_00010	6.62e-59	-	-	-	L	-	-	-	Phage terminase, small subunit
KOIEMPIK_00011	2.6e-97	-	-	-	S	-	-	-	Phage Terminase
KOIEMPIK_00012	1.35e-124	-	-	-	S	-	-	-	Phage Terminase
KOIEMPIK_00013	1.26e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
KOIEMPIK_00014	1.57e-262	-	-	-	S	-	-	-	Phage portal protein
KOIEMPIK_00015	7.98e-163	-	-	-	S	-	-	-	Clp protease
KOIEMPIK_00016	4.52e-266	-	-	-	S	-	-	-	Phage capsid family
KOIEMPIK_00017	5.37e-74	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KOIEMPIK_00018	1.21e-32	-	-	-	S	-	-	-	Phage head-tail joining protein
KOIEMPIK_00019	2.3e-51	-	-	-	-	-	-	-	-
KOIEMPIK_00020	1.25e-33	-	-	-	-	-	-	-	-
KOIEMPIK_00021	1.73e-89	-	-	-	S	-	-	-	Phage tail tube protein
KOIEMPIK_00023	5.58e-06	-	-	-	-	-	-	-	-
KOIEMPIK_00024	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
KOIEMPIK_00025	0.0	-	-	-	S	-	-	-	Phage tail protein
KOIEMPIK_00026	0.0	-	-	-	S	-	-	-	Phage minor structural protein
KOIEMPIK_00027	2.27e-229	-	-	-	-	-	-	-	-
KOIEMPIK_00030	6.08e-73	-	-	-	-	-	-	-	-
KOIEMPIK_00031	2.94e-260	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KOIEMPIK_00032	3.19e-50	-	-	-	S	-	-	-	Haemolysin XhlA
KOIEMPIK_00035	2.38e-294	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
KOIEMPIK_00036	0.0	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KOIEMPIK_00037	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KOIEMPIK_00038	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
KOIEMPIK_00039	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
KOIEMPIK_00040	2.3e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
KOIEMPIK_00041	3.81e-87	-	-	-	-	-	-	-	-
KOIEMPIK_00042	1.01e-100	-	-	-	-	-	-	-	-
KOIEMPIK_00043	6.35e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
KOIEMPIK_00044	7.8e-123	-	-	-	-	-	-	-	-
KOIEMPIK_00045	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KOIEMPIK_00046	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
KOIEMPIK_00047	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
KOIEMPIK_00048	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
KOIEMPIK_00049	3.4e-177	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
KOIEMPIK_00050	1.02e-66	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
KOIEMPIK_00051	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOIEMPIK_00052	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
KOIEMPIK_00053	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
KOIEMPIK_00054	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KOIEMPIK_00055	8.63e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
KOIEMPIK_00056	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KOIEMPIK_00057	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KOIEMPIK_00058	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
KOIEMPIK_00059	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
KOIEMPIK_00060	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KOIEMPIK_00061	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOIEMPIK_00062	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
KOIEMPIK_00063	2.58e-274	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
KOIEMPIK_00064	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
KOIEMPIK_00065	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
KOIEMPIK_00066	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KOIEMPIK_00067	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KOIEMPIK_00068	0.0	-	-	-	G	-	-	-	Major Facilitator
KOIEMPIK_00069	9.01e-276	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KOIEMPIK_00070	1.63e-121	-	-	-	-	-	-	-	-
KOIEMPIK_00071	1.92e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KOIEMPIK_00072	2.44e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
KOIEMPIK_00073	9.8e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KOIEMPIK_00074	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KOIEMPIK_00075	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KOIEMPIK_00076	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
KOIEMPIK_00077	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KOIEMPIK_00078	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KOIEMPIK_00079	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
KOIEMPIK_00080	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KOIEMPIK_00081	3.46e-265	pbpX2	-	-	V	-	-	-	Beta-lactamase
KOIEMPIK_00082	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
KOIEMPIK_00083	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOIEMPIK_00084	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
KOIEMPIK_00085	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOIEMPIK_00086	1.38e-311	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KOIEMPIK_00087	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOIEMPIK_00088	1.17e-65	-	-	-	-	-	-	-	-
KOIEMPIK_00089	4.78e-65	-	-	-	-	-	-	-	-
KOIEMPIK_00090	1.11e-147	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
KOIEMPIK_00091	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
KOIEMPIK_00092	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KOIEMPIK_00093	2.56e-76	-	-	-	-	-	-	-	-
KOIEMPIK_00094	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KOIEMPIK_00095	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KOIEMPIK_00096	1.35e-147	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
KOIEMPIK_00097	3.23e-214	-	-	-	G	-	-	-	Fructosamine kinase
KOIEMPIK_00098	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
KOIEMPIK_00099	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
KOIEMPIK_00100	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KOIEMPIK_00101	2.15e-131	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOIEMPIK_00102	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KOIEMPIK_00103	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOIEMPIK_00104	7.36e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KOIEMPIK_00105	3.65e-166	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
KOIEMPIK_00106	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KOIEMPIK_00107	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
KOIEMPIK_00108	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
KOIEMPIK_00109	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
KOIEMPIK_00110	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KOIEMPIK_00111	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
KOIEMPIK_00112	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KOIEMPIK_00113	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
KOIEMPIK_00114	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
KOIEMPIK_00115	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
KOIEMPIK_00116	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KOIEMPIK_00117	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KOIEMPIK_00118	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KOIEMPIK_00119	2.45e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_00120	2.59e-256	-	-	-	-	-	-	-	-
KOIEMPIK_00121	2.03e-251	-	-	-	-	-	-	-	-
KOIEMPIK_00122	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KOIEMPIK_00123	4.36e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_00124	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
KOIEMPIK_00125	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KOIEMPIK_00126	5.9e-103	-	-	-	K	-	-	-	MarR family
KOIEMPIK_00127	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KOIEMPIK_00129	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_00130	8.22e-171	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KOIEMPIK_00131	4.7e-262	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KOIEMPIK_00132	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
KOIEMPIK_00133	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KOIEMPIK_00135	9.29e-222	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
KOIEMPIK_00136	3.86e-205	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00137	8.62e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
KOIEMPIK_00138	4.15e-145	-	-	-	GM	-	-	-	NmrA-like family
KOIEMPIK_00139	1.52e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
KOIEMPIK_00140	2.13e-168	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KOIEMPIK_00141	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
KOIEMPIK_00142	3.72e-147	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
KOIEMPIK_00143	6.03e-36	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_00144	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_00145	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
KOIEMPIK_00146	1.86e-272	-	-	-	S	-	-	-	membrane
KOIEMPIK_00147	6.13e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_00148	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
KOIEMPIK_00149	5.7e-146	-	-	-	GM	-	-	-	epimerase
KOIEMPIK_00150	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
KOIEMPIK_00151	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
KOIEMPIK_00152	9.89e-138	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
KOIEMPIK_00153	5.87e-177	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
KOIEMPIK_00154	3.35e-148	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KOIEMPIK_00155	1.23e-230	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KOIEMPIK_00156	6.03e-270	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KOIEMPIK_00157	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00158	9.28e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
KOIEMPIK_00159	3.49e-307	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOIEMPIK_00160	1.05e-89	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
KOIEMPIK_00161	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
KOIEMPIK_00162	8.65e-221	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KOIEMPIK_00163	1.49e-281	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
KOIEMPIK_00164	3.34e-267	-	-	-	-	-	-	-	-
KOIEMPIK_00165	1.75e-117	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KOIEMPIK_00166	2.65e-81	-	-	-	P	-	-	-	Rhodanese Homology Domain
KOIEMPIK_00167	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KOIEMPIK_00168	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KOIEMPIK_00169	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_00170	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
KOIEMPIK_00171	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
KOIEMPIK_00172	1.96e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
KOIEMPIK_00173	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KOIEMPIK_00174	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
KOIEMPIK_00175	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KOIEMPIK_00177	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
KOIEMPIK_00178	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
KOIEMPIK_00179	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KOIEMPIK_00180	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
KOIEMPIK_00181	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
KOIEMPIK_00182	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
KOIEMPIK_00183	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
KOIEMPIK_00184	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOIEMPIK_00185	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KOIEMPIK_00186	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KOIEMPIK_00187	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KOIEMPIK_00188	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KOIEMPIK_00189	5.15e-247	-	-	-	S	-	-	-	Helix-turn-helix domain
KOIEMPIK_00190	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KOIEMPIK_00191	1.25e-39	-	-	-	M	-	-	-	Lysin motif
KOIEMPIK_00192	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
KOIEMPIK_00193	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
KOIEMPIK_00194	2.06e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
KOIEMPIK_00195	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KOIEMPIK_00196	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
KOIEMPIK_00197	9.1e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KOIEMPIK_00198	5.66e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KOIEMPIK_00199	4.96e-289	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KOIEMPIK_00200	6.46e-109	-	-	-	-	-	-	-	-
KOIEMPIK_00201	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_00202	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KOIEMPIK_00203	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KOIEMPIK_00204	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
KOIEMPIK_00205	1.19e-208	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
KOIEMPIK_00206	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
KOIEMPIK_00207	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
KOIEMPIK_00208	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
KOIEMPIK_00209	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_00210	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
KOIEMPIK_00211	1.5e-161	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
KOIEMPIK_00212	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
KOIEMPIK_00213	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
KOIEMPIK_00215	1.85e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KOIEMPIK_00216	2.04e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOIEMPIK_00217	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
KOIEMPIK_00218	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOIEMPIK_00219	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KOIEMPIK_00220	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
KOIEMPIK_00221	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KOIEMPIK_00222	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KOIEMPIK_00223	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
KOIEMPIK_00224	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KOIEMPIK_00225	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOIEMPIK_00226	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOIEMPIK_00227	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00228	1.59e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
KOIEMPIK_00229	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
KOIEMPIK_00230	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOIEMPIK_00231	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
KOIEMPIK_00232	3.59e-204	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
KOIEMPIK_00233	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KOIEMPIK_00234	1.83e-314	-	-	-	M	-	-	-	Glycosyl transferase family group 2
KOIEMPIK_00235	1.86e-86	-	-	-	-	-	-	-	-
KOIEMPIK_00236	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KOIEMPIK_00237	1.73e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KOIEMPIK_00238	4.87e-123	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KOIEMPIK_00239	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOIEMPIK_00240	8.63e-275	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOIEMPIK_00241	6.51e-247	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KOIEMPIK_00242	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KOIEMPIK_00243	9.59e-290	-	-	-	-	-	-	-	-
KOIEMPIK_00244	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
KOIEMPIK_00245	4.51e-77	-	-	-	-	-	-	-	-
KOIEMPIK_00246	1.09e-178	-	-	-	-	-	-	-	-
KOIEMPIK_00247	7.13e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KOIEMPIK_00248	2.13e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
KOIEMPIK_00249	8.55e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
KOIEMPIK_00250	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
KOIEMPIK_00252	7.81e-264	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
KOIEMPIK_00253	6.64e-189	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
KOIEMPIK_00254	1.23e-63	-	-	-	-	-	-	-	-
KOIEMPIK_00255	3.15e-29	-	-	-	-	-	-	-	-
KOIEMPIK_00256	2.9e-170	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
KOIEMPIK_00257	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
KOIEMPIK_00258	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
KOIEMPIK_00259	1.97e-87	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00260	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
KOIEMPIK_00261	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KOIEMPIK_00262	5.3e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_00263	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
KOIEMPIK_00265	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
KOIEMPIK_00266	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
KOIEMPIK_00267	9.52e-25	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
KOIEMPIK_00268	7.13e-112	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
KOIEMPIK_00271	6.38e-92	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
KOIEMPIK_00272	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
KOIEMPIK_00273	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KOIEMPIK_00274	4.89e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
KOIEMPIK_00275	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KOIEMPIK_00276	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KOIEMPIK_00277	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KOIEMPIK_00278	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
KOIEMPIK_00279	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
KOIEMPIK_00280	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
KOIEMPIK_00281	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
KOIEMPIK_00282	1.99e-132	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
KOIEMPIK_00283	6.59e-28	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
KOIEMPIK_00284	1.86e-246	-	-	-	-	-	-	-	-
KOIEMPIK_00285	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KOIEMPIK_00286	5.46e-157	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KOIEMPIK_00287	8.41e-97	XK27_05710	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_00288	1.44e-234	-	-	-	V	-	-	-	LD-carboxypeptidase
KOIEMPIK_00289	1.75e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
KOIEMPIK_00290	1.64e-62	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_00291	3.32e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
KOIEMPIK_00292	9.18e-254	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
KOIEMPIK_00293	2.26e-95	-	-	-	S	-	-	-	SnoaL-like domain
KOIEMPIK_00294	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
KOIEMPIK_00295	3.65e-308	-	-	-	P	-	-	-	Major Facilitator Superfamily
KOIEMPIK_00296	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KOIEMPIK_00297	4.11e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
KOIEMPIK_00299	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KOIEMPIK_00300	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
KOIEMPIK_00301	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KOIEMPIK_00302	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
KOIEMPIK_00303	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KOIEMPIK_00304	1.34e-232	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KOIEMPIK_00305	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KOIEMPIK_00306	7.56e-109	-	-	-	T	-	-	-	Universal stress protein family
KOIEMPIK_00307	3.19e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KOIEMPIK_00308	1.41e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_00309	2.32e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOIEMPIK_00311	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
KOIEMPIK_00312	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
KOIEMPIK_00313	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
KOIEMPIK_00314	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
KOIEMPIK_00315	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
KOIEMPIK_00316	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
KOIEMPIK_00317	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
KOIEMPIK_00318	1.03e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
KOIEMPIK_00319	4.98e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KOIEMPIK_00320	9.62e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KOIEMPIK_00321	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KOIEMPIK_00322	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KOIEMPIK_00323	1.03e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KOIEMPIK_00324	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
KOIEMPIK_00325	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KOIEMPIK_00326	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
KOIEMPIK_00327	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KOIEMPIK_00328	6.53e-58	-	-	-	-	-	-	-	-
KOIEMPIK_00329	1.52e-67	-	-	-	-	-	-	-	-
KOIEMPIK_00330	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
KOIEMPIK_00331	1.04e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
KOIEMPIK_00332	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KOIEMPIK_00333	4.87e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
KOIEMPIK_00334	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KOIEMPIK_00335	1.06e-53	-	-	-	-	-	-	-	-
KOIEMPIK_00336	4e-40	-	-	-	S	-	-	-	CsbD-like
KOIEMPIK_00337	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
KOIEMPIK_00338	5.79e-21	-	-	-	-	-	-	-	-
KOIEMPIK_00339	1.51e-48	-	-	-	-	-	-	-	-
KOIEMPIK_00340	1.79e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
KOIEMPIK_00341	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
KOIEMPIK_00342	3.05e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KOIEMPIK_00343	4.98e-107	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
KOIEMPIK_00344	2.05e-55	-	-	-	-	-	-	-	-
KOIEMPIK_00345	3.16e-64	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
KOIEMPIK_00346	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
KOIEMPIK_00347	1.69e-276	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KOIEMPIK_00348	2.02e-39	-	-	-	-	-	-	-	-
KOIEMPIK_00349	1.48e-71	-	-	-	-	-	-	-	-
KOIEMPIK_00350	2.19e-07	-	-	-	K	-	-	-	transcriptional regulator
KOIEMPIK_00351	3.35e-111	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
KOIEMPIK_00352	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
KOIEMPIK_00353	0.0	-	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_00354	1.49e-121	-	-	-	K	-	-	-	transcriptional regulator
KOIEMPIK_00355	1.54e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KOIEMPIK_00356	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
KOIEMPIK_00357	1.46e-204	-	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_00358	2.1e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KOIEMPIK_00359	1.01e-128	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
KOIEMPIK_00360	3.13e-173	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
KOIEMPIK_00361	1.96e-178	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
KOIEMPIK_00362	6.17e-201	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KOIEMPIK_00363	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
KOIEMPIK_00364	7.23e-93	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
KOIEMPIK_00365	5.25e-96	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KOIEMPIK_00366	5.38e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KOIEMPIK_00367	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
KOIEMPIK_00368	8.89e-218	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
KOIEMPIK_00369	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOIEMPIK_00370	9.77e-231	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOIEMPIK_00371	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KOIEMPIK_00372	1.33e-228	yneE	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00373	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_00374	1.09e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
KOIEMPIK_00375	8.04e-254	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KOIEMPIK_00376	3.38e-274	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
KOIEMPIK_00377	4.84e-278	-	-	-	E	-	-	-	glutamate:sodium symporter activity
KOIEMPIK_00378	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KOIEMPIK_00379	3.53e-227	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
KOIEMPIK_00380	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
KOIEMPIK_00381	2.79e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KOIEMPIK_00382	7.29e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KOIEMPIK_00383	2.92e-138	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
KOIEMPIK_00384	8.61e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
KOIEMPIK_00385	7.03e-225	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KOIEMPIK_00386	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
KOIEMPIK_00387	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
KOIEMPIK_00389	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
KOIEMPIK_00390	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
KOIEMPIK_00391	9.06e-112	-	-	-	-	-	-	-	-
KOIEMPIK_00392	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KOIEMPIK_00393	3.2e-70	-	-	-	-	-	-	-	-
KOIEMPIK_00394	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KOIEMPIK_00395	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
KOIEMPIK_00396	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KOIEMPIK_00397	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
KOIEMPIK_00398	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
KOIEMPIK_00399	9.38e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KOIEMPIK_00400	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KOIEMPIK_00401	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KOIEMPIK_00402	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
KOIEMPIK_00403	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KOIEMPIK_00404	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOIEMPIK_00405	3.09e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KOIEMPIK_00406	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KOIEMPIK_00407	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
KOIEMPIK_00408	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KOIEMPIK_00409	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
KOIEMPIK_00410	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
KOIEMPIK_00411	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
KOIEMPIK_00412	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KOIEMPIK_00413	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
KOIEMPIK_00414	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
KOIEMPIK_00415	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KOIEMPIK_00416	1.49e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KOIEMPIK_00417	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOIEMPIK_00418	1.68e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KOIEMPIK_00419	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KOIEMPIK_00420	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
KOIEMPIK_00421	1.19e-73	-	-	-	-	-	-	-	-
KOIEMPIK_00422	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KOIEMPIK_00423	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KOIEMPIK_00424	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_00425	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_00426	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
KOIEMPIK_00427	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KOIEMPIK_00428	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
KOIEMPIK_00429	2.23e-204	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KOIEMPIK_00430	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOIEMPIK_00431	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOIEMPIK_00432	1.38e-193	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KOIEMPIK_00433	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KOIEMPIK_00434	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
KOIEMPIK_00435	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOIEMPIK_00436	1.41e-244	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KOIEMPIK_00437	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
KOIEMPIK_00438	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
KOIEMPIK_00439	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
KOIEMPIK_00440	8.15e-125	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00441	9.81e-27	-	-	-	-	-	-	-	-
KOIEMPIK_00445	2.97e-41	-	-	-	-	-	-	-	-
KOIEMPIK_00446	3.11e-73	-	-	-	-	-	-	-	-
KOIEMPIK_00447	3.55e-127	-	-	-	S	-	-	-	Protein conserved in bacteria
KOIEMPIK_00448	1.34e-232	-	-	-	-	-	-	-	-
KOIEMPIK_00449	1.77e-205	-	-	-	-	-	-	-	-
KOIEMPIK_00450	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
KOIEMPIK_00451	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
KOIEMPIK_00452	2.29e-225	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KOIEMPIK_00453	2.23e-178	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
KOIEMPIK_00454	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
KOIEMPIK_00455	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
KOIEMPIK_00456	1.56e-139	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
KOIEMPIK_00457	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
KOIEMPIK_00458	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
KOIEMPIK_00459	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
KOIEMPIK_00460	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KOIEMPIK_00461	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KOIEMPIK_00462	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KOIEMPIK_00463	0.0	-	-	-	S	-	-	-	membrane
KOIEMPIK_00464	8.38e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
KOIEMPIK_00465	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
KOIEMPIK_00466	9.3e-144	-	-	-	S	-	-	-	membrane
KOIEMPIK_00467	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOIEMPIK_00468	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
KOIEMPIK_00469	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KOIEMPIK_00470	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOIEMPIK_00471	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KOIEMPIK_00472	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KOIEMPIK_00473	3.46e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KOIEMPIK_00474	4.46e-179	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOIEMPIK_00475	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
KOIEMPIK_00476	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOIEMPIK_00477	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
KOIEMPIK_00478	2.36e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KOIEMPIK_00479	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
KOIEMPIK_00480	1.59e-217	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
KOIEMPIK_00481	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KOIEMPIK_00482	1.38e-155	csrR	-	-	K	-	-	-	response regulator
KOIEMPIK_00483	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KOIEMPIK_00484	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KOIEMPIK_00485	1.13e-225	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOIEMPIK_00486	3.21e-52	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KOIEMPIK_00487	9.55e-55	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KOIEMPIK_00488	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
KOIEMPIK_00489	1.09e-273	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
KOIEMPIK_00490	1.91e-179	yqeM	-	-	Q	-	-	-	Methyltransferase
KOIEMPIK_00491	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KOIEMPIK_00492	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
KOIEMPIK_00493	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KOIEMPIK_00494	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
KOIEMPIK_00495	2.1e-228	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
KOIEMPIK_00496	3.3e-126	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
KOIEMPIK_00497	6.32e-114	-	-	-	-	-	-	-	-
KOIEMPIK_00498	1.9e-315	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
KOIEMPIK_00499	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
KOIEMPIK_00500	1.35e-82	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KOIEMPIK_00501	7.09e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KOIEMPIK_00502	4.06e-306	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
KOIEMPIK_00503	4.59e-73	-	-	-	-	-	-	-	-
KOIEMPIK_00504	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KOIEMPIK_00505	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
KOIEMPIK_00506	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KOIEMPIK_00507	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOIEMPIK_00508	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
KOIEMPIK_00509	4.73e-315	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
KOIEMPIK_00510	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KOIEMPIK_00511	9.54e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KOIEMPIK_00512	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KOIEMPIK_00513	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KOIEMPIK_00514	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
KOIEMPIK_00515	8.54e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KOIEMPIK_00516	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KOIEMPIK_00517	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
KOIEMPIK_00518	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
KOIEMPIK_00519	1.11e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KOIEMPIK_00520	4.28e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
KOIEMPIK_00521	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
KOIEMPIK_00522	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
KOIEMPIK_00523	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
KOIEMPIK_00524	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
KOIEMPIK_00525	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
KOIEMPIK_00526	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KOIEMPIK_00527	1.45e-145	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOIEMPIK_00528	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
KOIEMPIK_00529	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KOIEMPIK_00530	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
KOIEMPIK_00531	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_00532	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_00533	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
KOIEMPIK_00534	7.9e-72	-	-	-	-	-	-	-	-
KOIEMPIK_00535	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KOIEMPIK_00536	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_00537	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_00538	3.36e-248	-	-	-	S	-	-	-	Fn3-like domain
KOIEMPIK_00539	4.75e-80	-	-	-	-	-	-	-	-
KOIEMPIK_00540	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_00541	3e-308	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
KOIEMPIK_00542	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_00543	2.71e-150	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
KOIEMPIK_00544	3.39e-138	-	-	-	-	-	-	-	-
KOIEMPIK_00545	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
KOIEMPIK_00546	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KOIEMPIK_00547	5.12e-285	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KOIEMPIK_00548	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
KOIEMPIK_00549	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KOIEMPIK_00550	0.0	-	-	-	S	-	-	-	membrane
KOIEMPIK_00551	5.72e-90	-	-	-	S	-	-	-	NUDIX domain
KOIEMPIK_00552	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KOIEMPIK_00553	3.3e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
KOIEMPIK_00554	1.18e-100	-	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
KOIEMPIK_00555	2.26e-167	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
KOIEMPIK_00556	1.13e-78	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	phosphatase
KOIEMPIK_00557	1.73e-134	llrE	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
KOIEMPIK_00558	5.27e-203	-	-	-	T	-	-	-	Histidine kinase
KOIEMPIK_00559	3.36e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
KOIEMPIK_00560	3e-127	-	-	-	-	-	-	-	-
KOIEMPIK_00561	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KOIEMPIK_00562	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KOIEMPIK_00563	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_00564	1.39e-232	-	-	-	M	-	-	-	Peptidase family S41
KOIEMPIK_00565	7.82e-278	-	-	-	-	-	-	-	-
KOIEMPIK_00566	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
KOIEMPIK_00567	0.0	yhaN	-	-	L	-	-	-	AAA domain
KOIEMPIK_00568	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
KOIEMPIK_00569	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
KOIEMPIK_00570	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
KOIEMPIK_00571	2.43e-18	-	-	-	-	-	-	-	-
KOIEMPIK_00572	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
KOIEMPIK_00573	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
KOIEMPIK_00574	3.29e-132	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
KOIEMPIK_00575	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
KOIEMPIK_00576	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOIEMPIK_00577	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
KOIEMPIK_00578	5.15e-252	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
KOIEMPIK_00579	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_00580	1.5e-310	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_00581	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KOIEMPIK_00582	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KOIEMPIK_00583	2.7e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
KOIEMPIK_00584	0.0	celR	-	-	K	-	-	-	PRD domain
KOIEMPIK_00585	6.25e-138	-	-	-	-	-	-	-	-
KOIEMPIK_00586	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
KOIEMPIK_00587	4.64e-106	-	-	-	-	-	-	-	-
KOIEMPIK_00588	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
KOIEMPIK_00589	3.48e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
KOIEMPIK_00592	1.79e-42	-	-	-	-	-	-	-	-
KOIEMPIK_00593	2.69e-316	dinF	-	-	V	-	-	-	MatE
KOIEMPIK_00594	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
KOIEMPIK_00595	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
KOIEMPIK_00596	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
KOIEMPIK_00597	9.14e-146	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
KOIEMPIK_00598	5.16e-292	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
KOIEMPIK_00599	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
KOIEMPIK_00600	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KOIEMPIK_00601	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KOIEMPIK_00602	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
KOIEMPIK_00603	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
KOIEMPIK_00604	3.89e-237	-	-	-	-	-	-	-	-
KOIEMPIK_00605	9.03e-16	-	-	-	-	-	-	-	-
KOIEMPIK_00606	4.29e-87	-	-	-	-	-	-	-	-
KOIEMPIK_00609	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
KOIEMPIK_00610	7.12e-62	-	-	-	-	-	-	-	-
KOIEMPIK_00611	8.82e-119	-	-	-	-	-	-	-	-
KOIEMPIK_00612	1.28e-110	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
KOIEMPIK_00613	1.06e-146	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_00614	4.56e-78	-	-	-	-	-	-	-	-
KOIEMPIK_00615	5.37e-74	-	-	-	-	-	-	-	-
KOIEMPIK_00616	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KOIEMPIK_00617	6.18e-274	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KOIEMPIK_00618	7.83e-140	-	-	-	-	-	-	-	-
KOIEMPIK_00619	3.27e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KOIEMPIK_00620	1.55e-203	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KOIEMPIK_00621	5.48e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_00622	2.12e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_00623	9.49e-196	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOIEMPIK_00625	6.05e-225	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
KOIEMPIK_00626	7.2e-200	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_00627	1.72e-162	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
KOIEMPIK_00629	1.48e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
KOIEMPIK_00630	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KOIEMPIK_00631	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
KOIEMPIK_00632	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
KOIEMPIK_00633	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KOIEMPIK_00634	3.05e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_00635	2.27e-221	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KOIEMPIK_00636	1.24e-259	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
KOIEMPIK_00637	2.16e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KOIEMPIK_00638	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
KOIEMPIK_00639	9.06e-195	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KOIEMPIK_00640	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
KOIEMPIK_00641	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KOIEMPIK_00642	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
KOIEMPIK_00643	1.78e-161	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
KOIEMPIK_00644	5.13e-138	mraW1	-	-	J	-	-	-	Putative rRNA methylase
KOIEMPIK_00645	9.32e-40	-	-	-	-	-	-	-	-
KOIEMPIK_00646	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KOIEMPIK_00647	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KOIEMPIK_00648	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
KOIEMPIK_00649	4.05e-309	-	-	-	N	-	-	-	Cell shape-determining protein MreB
KOIEMPIK_00650	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_00651	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KOIEMPIK_00652	5.79e-158	-	-	-	-	-	-	-	-
KOIEMPIK_00653	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_00654	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KOIEMPIK_00655	7.89e-216	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
KOIEMPIK_00656	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
KOIEMPIK_00657	2.53e-240	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
KOIEMPIK_00658	1.09e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KOIEMPIK_00660	2.07e-200	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
KOIEMPIK_00661	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_00662	1.25e-124	-	-	-	-	-	-	-	-
KOIEMPIK_00663	4.48e-237	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
KOIEMPIK_00664	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
KOIEMPIK_00676	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
KOIEMPIK_00679	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KOIEMPIK_00680	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
KOIEMPIK_00681	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KOIEMPIK_00682	6.56e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KOIEMPIK_00683	8.79e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KOIEMPIK_00684	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KOIEMPIK_00685	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
KOIEMPIK_00686	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KOIEMPIK_00687	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
KOIEMPIK_00688	5.6e-41	-	-	-	-	-	-	-	-
KOIEMPIK_00689	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
KOIEMPIK_00690	2.5e-132	-	-	-	L	-	-	-	Integrase
KOIEMPIK_00691	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KOIEMPIK_00692	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KOIEMPIK_00693	4.86e-258	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KOIEMPIK_00694	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOIEMPIK_00695	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOIEMPIK_00696	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KOIEMPIK_00697	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
KOIEMPIK_00698	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KOIEMPIK_00699	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_00700	1.74e-251	-	-	-	M	-	-	-	MucBP domain
KOIEMPIK_00701	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_00702	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KOIEMPIK_00703	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KOIEMPIK_00704	3.36e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
KOIEMPIK_00705	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
KOIEMPIK_00706	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
KOIEMPIK_00707	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
KOIEMPIK_00708	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
KOIEMPIK_00709	2.97e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KOIEMPIK_00710	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
KOIEMPIK_00711	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
KOIEMPIK_00712	5.23e-172	lytE	-	-	M	-	-	-	NlpC/P60 family
KOIEMPIK_00713	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
KOIEMPIK_00714	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
KOIEMPIK_00715	1.9e-168	-	-	-	-	-	-	-	-
KOIEMPIK_00716	6.87e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
KOIEMPIK_00717	1.64e-35	-	-	-	-	-	-	-	-
KOIEMPIK_00718	1.95e-41	-	-	-	-	-	-	-	-
KOIEMPIK_00719	1.04e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
KOIEMPIK_00720	1.06e-68	-	-	-	-	-	-	-	-
KOIEMPIK_00721	1.38e-155	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
KOIEMPIK_00722	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
KOIEMPIK_00723	5.36e-97	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KOIEMPIK_00724	0.0	-	-	-	M	-	-	-	domain protein
KOIEMPIK_00725	6.86e-175	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KOIEMPIK_00726	3.43e-189	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
KOIEMPIK_00727	5.06e-260	cps3I	-	-	G	-	-	-	Acyltransferase family
KOIEMPIK_00728	1.03e-264	cps3H	-	-	-	-	-	-	-
KOIEMPIK_00729	1.73e-207	cps3F	-	-	-	-	-	-	-
KOIEMPIK_00730	2.92e-145	cps3E	-	-	-	-	-	-	-
KOIEMPIK_00731	6.79e-261	cps3D	-	-	-	-	-	-	-
KOIEMPIK_00732	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
KOIEMPIK_00733	1.89e-228	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
KOIEMPIK_00734	1.41e-169	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
KOIEMPIK_00735	9.2e-24	cps2K	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
KOIEMPIK_00736	1.6e-240	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KOIEMPIK_00737	1.5e-105	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
KOIEMPIK_00739	3.06e-112	-	-	-	V	-	-	-	Glycosyl transferase, family 2
KOIEMPIK_00740	9.69e-175	-	-	-	M	-	-	-	Teichoic acid biosynthesis protein
KOIEMPIK_00741	1.1e-44	-	-	-	M	-	-	-	Pfam:DUF1792
KOIEMPIK_00742	6.72e-56	wcaA	-	-	M	-	-	-	Glycosyl transferase family 2
KOIEMPIK_00743	8.04e-158	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
KOIEMPIK_00744	1.14e-227	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
KOIEMPIK_00745	1.62e-182	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
KOIEMPIK_00746	7.38e-167	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
KOIEMPIK_00747	2.02e-171	epsB	-	-	M	-	-	-	biosynthesis protein
KOIEMPIK_00748	5.99e-130	-	-	-	L	-	-	-	Integrase
KOIEMPIK_00749	1.05e-188	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KOIEMPIK_00750	4.88e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KOIEMPIK_00751	1.39e-262	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOIEMPIK_00752	1.37e-140	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KOIEMPIK_00753	1.53e-187	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KOIEMPIK_00754	8.96e-49	-	-	-	G	-	-	-	PFAM glycoside hydrolase family 39
KOIEMPIK_00756	1.46e-68	-	-	-	-	-	-	-	-
KOIEMPIK_00757	6.32e-68	-	-	-	G	-	-	-	Glycosyltransferase Family 4
KOIEMPIK_00758	3.21e-168	-	-	GT4	M	ko:K12996	-	ko00000,ko01000,ko01003,ko01005	Domain of unknown function (DUF1972)
KOIEMPIK_00759	1.57e-53	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
KOIEMPIK_00760	1.09e-61	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOIEMPIK_00761	6.7e-25	-	-	-	S	-	-	-	Glycosyl transferase, family 2
KOIEMPIK_00762	3.59e-69	pbpX2	-	-	V	-	-	-	Beta-lactamase
KOIEMPIK_00764	1.6e-35	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KOIEMPIK_00765	7.7e-43	-	-	-	E	-	-	-	Zn peptidase
KOIEMPIK_00766	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_00767	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KOIEMPIK_00768	1.01e-199	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
KOIEMPIK_00769	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KOIEMPIK_00770	3.85e-280	pbpX	-	-	V	-	-	-	Beta-lactamase
KOIEMPIK_00771	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
KOIEMPIK_00772	2.9e-139	-	-	-	-	-	-	-	-
KOIEMPIK_00773	7.62e-97	-	-	-	-	-	-	-	-
KOIEMPIK_00775	1.12e-209	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_00776	5.73e-316	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_00777	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
KOIEMPIK_00779	3.08e-240	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KOIEMPIK_00780	2.36e-57	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
KOIEMPIK_00781	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
KOIEMPIK_00782	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
KOIEMPIK_00783	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
KOIEMPIK_00784	1.9e-186	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KOIEMPIK_00785	5.63e-196	gntR	-	-	K	-	-	-	rpiR family
KOIEMPIK_00786	2.87e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_00787	7.06e-307	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_00788	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
KOIEMPIK_00789	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_00790	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOIEMPIK_00791	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
KOIEMPIK_00792	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOIEMPIK_00793	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KOIEMPIK_00794	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOIEMPIK_00795	2.23e-261	camS	-	-	S	-	-	-	sex pheromone
KOIEMPIK_00796	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KOIEMPIK_00797	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
KOIEMPIK_00798	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KOIEMPIK_00799	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
KOIEMPIK_00800	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KOIEMPIK_00801	2.92e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
KOIEMPIK_00802	9.47e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KOIEMPIK_00803	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
KOIEMPIK_00804	2.11e-233	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KOIEMPIK_00805	1.27e-206	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
KOIEMPIK_00806	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KOIEMPIK_00807	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KOIEMPIK_00808	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
KOIEMPIK_00809	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
KOIEMPIK_00810	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
KOIEMPIK_00811	2.56e-34	-	-	-	-	-	-	-	-
KOIEMPIK_00812	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
KOIEMPIK_00813	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
KOIEMPIK_00814	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
KOIEMPIK_00815	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
KOIEMPIK_00816	6.5e-215	mleR	-	-	K	-	-	-	LysR family
KOIEMPIK_00817	4.35e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
KOIEMPIK_00818	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
KOIEMPIK_00819	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KOIEMPIK_00820	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KOIEMPIK_00822	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
KOIEMPIK_00823	3.32e-210	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
KOIEMPIK_00824	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
KOIEMPIK_00825	2.52e-240	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
KOIEMPIK_00826	5.51e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
KOIEMPIK_00827	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
KOIEMPIK_00828	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KOIEMPIK_00829	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KOIEMPIK_00830	1.18e-66	-	-	-	-	-	-	-	-
KOIEMPIK_00831	3e-222	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KOIEMPIK_00832	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
KOIEMPIK_00833	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KOIEMPIK_00834	9.07e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
KOIEMPIK_00835	6.33e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_00836	3.01e-225	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
KOIEMPIK_00837	2.01e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
KOIEMPIK_00838	1.51e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
KOIEMPIK_00839	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KOIEMPIK_00841	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KOIEMPIK_00842	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
KOIEMPIK_00843	2.35e-211	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOIEMPIK_00844	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KOIEMPIK_00845	2.61e-259	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
KOIEMPIK_00846	1e-234	-	-	-	S	-	-	-	Membrane
KOIEMPIK_00847	2.44e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KOIEMPIK_00848	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
KOIEMPIK_00849	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KOIEMPIK_00850	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KOIEMPIK_00851	9.72e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOIEMPIK_00852	2.85e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOIEMPIK_00853	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOIEMPIK_00854	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOIEMPIK_00855	3.19e-194	-	-	-	S	-	-	-	FMN_bind
KOIEMPIK_00856	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KOIEMPIK_00857	5.37e-112	-	-	-	S	-	-	-	NusG domain II
KOIEMPIK_00858	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
KOIEMPIK_00859	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
KOIEMPIK_00860	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
KOIEMPIK_00861	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOIEMPIK_00862	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KOIEMPIK_00863	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KOIEMPIK_00864	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KOIEMPIK_00865	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KOIEMPIK_00866	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KOIEMPIK_00867	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KOIEMPIK_00868	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
KOIEMPIK_00869	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KOIEMPIK_00870	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KOIEMPIK_00871	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KOIEMPIK_00872	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KOIEMPIK_00873	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KOIEMPIK_00874	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KOIEMPIK_00875	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KOIEMPIK_00876	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KOIEMPIK_00877	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
KOIEMPIK_00878	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KOIEMPIK_00879	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KOIEMPIK_00880	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KOIEMPIK_00881	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KOIEMPIK_00882	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KOIEMPIK_00883	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KOIEMPIK_00884	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
KOIEMPIK_00885	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KOIEMPIK_00886	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
KOIEMPIK_00887	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KOIEMPIK_00888	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KOIEMPIK_00889	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KOIEMPIK_00890	8.58e-149	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
KOIEMPIK_00891	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOIEMPIK_00892	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOIEMPIK_00893	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_00894	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KOIEMPIK_00895	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
KOIEMPIK_00903	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_00904	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOIEMPIK_00905	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
KOIEMPIK_00906	1.06e-152	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
KOIEMPIK_00907	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
KOIEMPIK_00908	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
KOIEMPIK_00909	1.7e-118	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00910	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KOIEMPIK_00911	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KOIEMPIK_00912	2.05e-153	-	-	-	I	-	-	-	phosphatase
KOIEMPIK_00913	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KOIEMPIK_00914	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KOIEMPIK_00915	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
KOIEMPIK_00916	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
KOIEMPIK_00917	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
KOIEMPIK_00918	1.36e-77	-	-	-	-	-	-	-	-
KOIEMPIK_00919	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
KOIEMPIK_00920	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KOIEMPIK_00921	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
KOIEMPIK_00922	5.73e-114	-	-	-	-	-	-	-	-
KOIEMPIK_00923	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
KOIEMPIK_00924	4.09e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
KOIEMPIK_00925	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
KOIEMPIK_00926	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KOIEMPIK_00927	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
KOIEMPIK_00928	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOIEMPIK_00929	0.0	xylP2	-	-	G	-	-	-	symporter
KOIEMPIK_00930	7.32e-247	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KOIEMPIK_00931	1.76e-155	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
KOIEMPIK_00932	1.31e-129	-	-	-	K	-	-	-	FR47-like protein
KOIEMPIK_00933	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
KOIEMPIK_00934	3.28e-278	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
KOIEMPIK_00935	1.12e-243	-	-	-	-	-	-	-	-
KOIEMPIK_00936	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KOIEMPIK_00937	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KOIEMPIK_00938	1.36e-208	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KOIEMPIK_00939	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
KOIEMPIK_00940	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
KOIEMPIK_00941	5.44e-56	-	-	-	-	-	-	-	-
KOIEMPIK_00942	1.08e-289	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KOIEMPIK_00943	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KOIEMPIK_00944	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
KOIEMPIK_00945	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
KOIEMPIK_00946	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KOIEMPIK_00947	3.54e-105	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00949	0.0	-	-	-	C	-	-	-	FMN_bind
KOIEMPIK_00950	1.6e-219	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_00951	1.09e-123	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_00952	7.45e-180	-	-	-	K	-	-	-	sequence-specific DNA binding
KOIEMPIK_00953	1.27e-115	-	-	-	S	-	-	-	AAA domain
KOIEMPIK_00954	1.42e-08	-	-	-	-	-	-	-	-
KOIEMPIK_00955	0.0	-	-	-	M	-	-	-	MucBP domain
KOIEMPIK_00956	2.31e-117	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
KOIEMPIK_00957	3.37e-60	-	-	-	S	-	-	-	MazG-like family
KOIEMPIK_00958	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
KOIEMPIK_00959	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
KOIEMPIK_00960	2.19e-131	-	-	-	G	-	-	-	Glycogen debranching enzyme
KOIEMPIK_00961	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
KOIEMPIK_00962	4.2e-208	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
KOIEMPIK_00963	1.59e-189	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
KOIEMPIK_00964	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KOIEMPIK_00965	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
KOIEMPIK_00966	5.74e-32	-	-	-	-	-	-	-	-
KOIEMPIK_00967	1.95e-116	-	-	-	-	-	-	-	-
KOIEMPIK_00968	7.38e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
KOIEMPIK_00969	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
KOIEMPIK_00970	3.61e-61	-	-	-	S	-	-	-	MORN repeat
KOIEMPIK_00971	3.5e-299	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
KOIEMPIK_00972	1.92e-301	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
KOIEMPIK_00973	3.08e-74	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KOIEMPIK_00974	1.16e-142	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_00975	1.37e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_00976	1.08e-71	-	-	-	-	-	-	-	-
KOIEMPIK_00977	1.38e-75	-	-	-	-	-	-	-	-
KOIEMPIK_00978	6.67e-30	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KOIEMPIK_00979	8.56e-38	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KOIEMPIK_00980	1.51e-22	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
KOIEMPIK_00981	4.77e-48	-	-	-	L	-	-	-	Helix-turn-helix domain
KOIEMPIK_00983	3.56e-171	spoVK	-	-	O	ko:K06413	-	ko00000	ATPase family associated with various cellular activities (AAA)
KOIEMPIK_00985	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
KOIEMPIK_00986	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
KOIEMPIK_00987	3.59e-212	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
KOIEMPIK_00988	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
KOIEMPIK_00989	2.84e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
KOIEMPIK_00990	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
KOIEMPIK_00991	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
KOIEMPIK_00992	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
KOIEMPIK_00993	2.23e-164	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
KOIEMPIK_00994	1.61e-36	-	-	-	-	-	-	-	-
KOIEMPIK_00995	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
KOIEMPIK_00996	1.88e-101	rppH3	-	-	F	-	-	-	NUDIX domain
KOIEMPIK_00997	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KOIEMPIK_00998	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_00999	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KOIEMPIK_01000	8.85e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KOIEMPIK_01001	3.08e-93	-	-	-	K	-	-	-	MarR family
KOIEMPIK_01002	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
KOIEMPIK_01003	2.55e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KOIEMPIK_01004	8.73e-315	steT	-	-	E	ko:K03294	-	ko00000	amino acid
KOIEMPIK_01005	1.24e-179	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
KOIEMPIK_01006	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KOIEMPIK_01007	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KOIEMPIK_01008	1e-107	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KOIEMPIK_01009	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_01010	1.81e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_01011	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
KOIEMPIK_01012	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_01014	1.28e-54	-	-	-	-	-	-	-	-
KOIEMPIK_01015	5.1e-218	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOIEMPIK_01016	1.86e-267	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KOIEMPIK_01017	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
KOIEMPIK_01018	1.01e-188	-	-	-	-	-	-	-	-
KOIEMPIK_01019	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
KOIEMPIK_01020	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
KOIEMPIK_01021	7.32e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
KOIEMPIK_01022	1.48e-27	-	-	-	-	-	-	-	-
KOIEMPIK_01023	3.05e-95	-	-	-	F	-	-	-	Nudix hydrolase
KOIEMPIK_01024	7.76e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
KOIEMPIK_01025	6.12e-115	-	-	-	-	-	-	-	-
KOIEMPIK_01026	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
KOIEMPIK_01027	1.09e-60	-	-	-	-	-	-	-	-
KOIEMPIK_01028	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
KOIEMPIK_01029	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KOIEMPIK_01030	0.0	oatA	-	-	I	-	-	-	Acyltransferase
KOIEMPIK_01031	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KOIEMPIK_01032	6.37e-232	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KOIEMPIK_01033	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KOIEMPIK_01034	5.47e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
KOIEMPIK_01035	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KOIEMPIK_01036	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
KOIEMPIK_01037	1.36e-27	-	-	-	-	-	-	-	-
KOIEMPIK_01038	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_01039	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
KOIEMPIK_01040	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KOIEMPIK_01041	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KOIEMPIK_01042	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KOIEMPIK_01043	1.06e-314	-	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_01044	2.08e-117	-	-	-	V	-	-	-	VanZ like family
KOIEMPIK_01045	3.88e-46	-	-	-	-	-	-	-	-
KOIEMPIK_01046	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
KOIEMPIK_01048	4.13e-182	-	-	-	-	-	-	-	-
KOIEMPIK_01049	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KOIEMPIK_01050	1.15e-41	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
KOIEMPIK_01051	7.34e-180	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KOIEMPIK_01052	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
KOIEMPIK_01053	2.49e-95	-	-	-	-	-	-	-	-
KOIEMPIK_01054	3.38e-70	-	-	-	-	-	-	-	-
KOIEMPIK_01055	1.7e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KOIEMPIK_01056	4.22e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_01057	9.79e-191	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
KOIEMPIK_01058	3.15e-158	-	-	-	T	-	-	-	EAL domain
KOIEMPIK_01059	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KOIEMPIK_01060	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KOIEMPIK_01061	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
KOIEMPIK_01062	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KOIEMPIK_01063	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
KOIEMPIK_01064	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
KOIEMPIK_01065	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KOIEMPIK_01066	6.24e-214	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
KOIEMPIK_01067	1.71e-210	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
KOIEMPIK_01068	8.47e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
KOIEMPIK_01069	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KOIEMPIK_01070	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_01071	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
KOIEMPIK_01072	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
KOIEMPIK_01073	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KOIEMPIK_01074	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KOIEMPIK_01075	6.57e-136	-	-	-	-	-	-	-	-
KOIEMPIK_01076	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_01077	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_01078	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
KOIEMPIK_01079	2.4e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KOIEMPIK_01080	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KOIEMPIK_01081	6.62e-180	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
KOIEMPIK_01082	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KOIEMPIK_01083	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
KOIEMPIK_01084	5.11e-171	-	-	-	-	-	-	-	-
KOIEMPIK_01085	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOIEMPIK_01086	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KOIEMPIK_01087	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
KOIEMPIK_01088	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOIEMPIK_01089	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
KOIEMPIK_01090	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
KOIEMPIK_01092	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOIEMPIK_01093	6.3e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOIEMPIK_01094	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KOIEMPIK_01095	7e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
KOIEMPIK_01096	4.56e-243	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
KOIEMPIK_01097	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
KOIEMPIK_01098	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
KOIEMPIK_01099	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
KOIEMPIK_01100	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
KOIEMPIK_01101	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KOIEMPIK_01102	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KOIEMPIK_01103	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOIEMPIK_01104	9.45e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
KOIEMPIK_01105	8.83e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
KOIEMPIK_01106	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KOIEMPIK_01107	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
KOIEMPIK_01108	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
KOIEMPIK_01109	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KOIEMPIK_01110	4.7e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
KOIEMPIK_01111	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
KOIEMPIK_01112	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KOIEMPIK_01113	7.91e-172	-	-	-	T	-	-	-	diguanylate cyclase activity
KOIEMPIK_01114	0.0	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
KOIEMPIK_01115	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
KOIEMPIK_01116	8.36e-257	-	-	-	S	-	-	-	Protein conserved in bacteria
KOIEMPIK_01117	2.45e-310	-	-	-	-	-	-	-	-
KOIEMPIK_01118	3.69e-206	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
KOIEMPIK_01119	0.0	nox	-	-	C	-	-	-	NADH oxidase
KOIEMPIK_01120	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
KOIEMPIK_01121	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
KOIEMPIK_01122	1.15e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
KOIEMPIK_01123	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KOIEMPIK_01124	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KOIEMPIK_01125	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
KOIEMPIK_01126	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
KOIEMPIK_01127	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
KOIEMPIK_01128	2.31e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOIEMPIK_01129	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOIEMPIK_01130	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
KOIEMPIK_01131	2.22e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
KOIEMPIK_01132	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KOIEMPIK_01133	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KOIEMPIK_01134	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KOIEMPIK_01135	1.28e-276	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
KOIEMPIK_01136	1.69e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KOIEMPIK_01137	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOIEMPIK_01138	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KOIEMPIK_01139	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
KOIEMPIK_01140	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
KOIEMPIK_01141	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
KOIEMPIK_01142	6.57e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
KOIEMPIK_01143	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
KOIEMPIK_01144	0.0	ydaO	-	-	E	-	-	-	amino acid
KOIEMPIK_01145	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KOIEMPIK_01146	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KOIEMPIK_01147	1.68e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01148	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KOIEMPIK_01149	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
KOIEMPIK_01150	7.63e-251	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KOIEMPIK_01151	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KOIEMPIK_01152	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
KOIEMPIK_01153	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
KOIEMPIK_01154	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
KOIEMPIK_01155	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KOIEMPIK_01156	2.65e-177	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
KOIEMPIK_01157	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_01158	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
KOIEMPIK_01159	8.87e-269	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
KOIEMPIK_01160	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KOIEMPIK_01161	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
KOIEMPIK_01162	1.53e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KOIEMPIK_01163	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
KOIEMPIK_01164	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
KOIEMPIK_01165	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
KOIEMPIK_01166	6.36e-153	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KOIEMPIK_01167	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
KOIEMPIK_01168	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KOIEMPIK_01169	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KOIEMPIK_01170	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOIEMPIK_01171	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KOIEMPIK_01172	1.11e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
KOIEMPIK_01173	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
KOIEMPIK_01174	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOIEMPIK_01175	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOIEMPIK_01176	2.37e-140	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
KOIEMPIK_01177	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KOIEMPIK_01178	1.46e-87	-	-	-	L	-	-	-	nuclease
KOIEMPIK_01179	5.22e-229	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
KOIEMPIK_01180	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KOIEMPIK_01181	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KOIEMPIK_01182	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KOIEMPIK_01183	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KOIEMPIK_01184	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_01185	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
KOIEMPIK_01186	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KOIEMPIK_01187	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
KOIEMPIK_01188	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
KOIEMPIK_01189	5.87e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
KOIEMPIK_01190	2.48e-176	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOIEMPIK_01191	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KOIEMPIK_01192	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KOIEMPIK_01193	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KOIEMPIK_01194	4.91e-265	yacL	-	-	S	-	-	-	domain protein
KOIEMPIK_01195	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KOIEMPIK_01196	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
KOIEMPIK_01197	8.47e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
KOIEMPIK_01198	1.33e-157	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KOIEMPIK_01199	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
KOIEMPIK_01200	1.12e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
KOIEMPIK_01201	1.11e-164	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOIEMPIK_01202	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
KOIEMPIK_01203	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
KOIEMPIK_01204	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KOIEMPIK_01205	4.1e-176	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
KOIEMPIK_01206	1.49e-183	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KOIEMPIK_01207	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
KOIEMPIK_01208	2.18e-83	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
KOIEMPIK_01209	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOIEMPIK_01210	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KOIEMPIK_01211	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KOIEMPIK_01212	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
KOIEMPIK_01213	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
KOIEMPIK_01214	1.87e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
KOIEMPIK_01215	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
KOIEMPIK_01216	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KOIEMPIK_01217	3.36e-199	-	-	-	G	-	-	-	Peptidase_C39 like family
KOIEMPIK_01219	1.19e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KOIEMPIK_01220	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
KOIEMPIK_01221	3.76e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
KOIEMPIK_01222	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
KOIEMPIK_01223	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
KOIEMPIK_01224	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KOIEMPIK_01225	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KOIEMPIK_01226	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOIEMPIK_01227	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KOIEMPIK_01228	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
KOIEMPIK_01229	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KOIEMPIK_01230	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOIEMPIK_01231	4.33e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KOIEMPIK_01232	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
KOIEMPIK_01233	1.31e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
KOIEMPIK_01234	1.38e-71	-	-	-	S	-	-	-	Cupin domain
KOIEMPIK_01235	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
KOIEMPIK_01239	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KOIEMPIK_01240	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
KOIEMPIK_01243	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
KOIEMPIK_01246	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
KOIEMPIK_01247	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOIEMPIK_01248	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KOIEMPIK_01249	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KOIEMPIK_01250	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
KOIEMPIK_01251	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KOIEMPIK_01252	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
KOIEMPIK_01253	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
KOIEMPIK_01255	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
KOIEMPIK_01256	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
KOIEMPIK_01257	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KOIEMPIK_01258	8.29e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KOIEMPIK_01259	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
KOIEMPIK_01260	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
KOIEMPIK_01261	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
KOIEMPIK_01262	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
KOIEMPIK_01263	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KOIEMPIK_01264	5.21e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
KOIEMPIK_01265	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
KOIEMPIK_01266	9.73e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KOIEMPIK_01267	1.79e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KOIEMPIK_01268	1.06e-259	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KOIEMPIK_01269	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KOIEMPIK_01270	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
KOIEMPIK_01271	3.03e-202	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KOIEMPIK_01272	1.37e-248	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
KOIEMPIK_01273	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KOIEMPIK_01274	4.28e-84	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
KOIEMPIK_01275	1.43e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOIEMPIK_01276	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KOIEMPIK_01277	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KOIEMPIK_01278	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KOIEMPIK_01279	1.84e-189	-	-	-	-	-	-	-	-
KOIEMPIK_01280	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
KOIEMPIK_01281	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
KOIEMPIK_01282	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
KOIEMPIK_01283	2.57e-274	-	-	-	J	-	-	-	translation release factor activity
KOIEMPIK_01284	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
KOIEMPIK_01285	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KOIEMPIK_01286	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOIEMPIK_01287	2.41e-37	-	-	-	-	-	-	-	-
KOIEMPIK_01288	2.3e-170	-	-	-	S	-	-	-	YheO-like PAS domain
KOIEMPIK_01289	2.81e-202	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KOIEMPIK_01290	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
KOIEMPIK_01291	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
KOIEMPIK_01292	5.84e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOIEMPIK_01293	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KOIEMPIK_01294	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KOIEMPIK_01295	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
KOIEMPIK_01296	2.68e-201	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
KOIEMPIK_01297	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
KOIEMPIK_01298	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
KOIEMPIK_01299	3.53e-178	-	-	-	-	-	-	-	-
KOIEMPIK_01300	1.82e-232	-	-	-	S	-	-	-	DUF218 domain
KOIEMPIK_01301	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOIEMPIK_01302	2.82e-196	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KOIEMPIK_01303	1.34e-297	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KOIEMPIK_01304	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
KOIEMPIK_01305	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
KOIEMPIK_01306	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KOIEMPIK_01307	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
KOIEMPIK_01308	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KOIEMPIK_01309	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
KOIEMPIK_01310	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOIEMPIK_01311	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KOIEMPIK_01312	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
KOIEMPIK_01313	2.48e-203	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
KOIEMPIK_01314	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KOIEMPIK_01315	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
KOIEMPIK_01316	3.74e-204	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
KOIEMPIK_01317	1.24e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
KOIEMPIK_01318	1.82e-226	-	-	-	-	-	-	-	-
KOIEMPIK_01319	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
KOIEMPIK_01320	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
KOIEMPIK_01321	3.43e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOIEMPIK_01322	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KOIEMPIK_01323	6.97e-209	-	-	-	GK	-	-	-	ROK family
KOIEMPIK_01324	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_01325	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_01326	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
KOIEMPIK_01327	9.68e-34	-	-	-	-	-	-	-	-
KOIEMPIK_01328	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_01329	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
KOIEMPIK_01330	1.36e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
KOIEMPIK_01331	5.87e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
KOIEMPIK_01332	0.0	-	-	-	L	-	-	-	DNA helicase
KOIEMPIK_01333	5.5e-42	-	-	-	-	-	-	-	-
KOIEMPIK_01334	6.46e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01335	1.46e-140	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01336	3.26e-151	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01337	1.57e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01338	6.78e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
KOIEMPIK_01339	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KOIEMPIK_01340	8.82e-32	-	-	-	-	-	-	-	-
KOIEMPIK_01341	1.93e-31	plnF	-	-	-	-	-	-	-
KOIEMPIK_01342	3.32e-166	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01343	5.61e-169	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KOIEMPIK_01344	1.32e-141	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KOIEMPIK_01346	3.81e-150	-	-	-	-	-	-	-	-
KOIEMPIK_01349	8.8e-265	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KOIEMPIK_01350	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KOIEMPIK_01351	8.38e-192	-	-	-	S	-	-	-	hydrolase
KOIEMPIK_01352	9.59e-212	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_01353	3.41e-187	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
KOIEMPIK_01354	7.81e-263	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
KOIEMPIK_01355	1.08e-152	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KOIEMPIK_01357	3.27e-81	-	-	-	-	-	-	-	-
KOIEMPIK_01358	8.72e-24	-	-	-	-	-	-	-	-
KOIEMPIK_01360	2e-44	-	-	-	-	-	-	-	-
KOIEMPIK_01362	1.12e-72	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
KOIEMPIK_01363	0.0	-	-	-	M	-	-	-	domain protein
KOIEMPIK_01364	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KOIEMPIK_01365	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
KOIEMPIK_01366	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KOIEMPIK_01367	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KOIEMPIK_01368	4.47e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_01369	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KOIEMPIK_01370	1.17e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
KOIEMPIK_01371	4.01e-206	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_01372	3.66e-224	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
KOIEMPIK_01373	9.88e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KOIEMPIK_01374	1.52e-103	-	-	-	-	-	-	-	-
KOIEMPIK_01375	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
KOIEMPIK_01376	3.79e-293	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
KOIEMPIK_01377	1.31e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
KOIEMPIK_01378	1.08e-71	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
KOIEMPIK_01379	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
KOIEMPIK_01380	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KOIEMPIK_01381	3.51e-131	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
KOIEMPIK_01382	8.95e-60	-	-	-	-	-	-	-	-
KOIEMPIK_01383	9e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KOIEMPIK_01384	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
KOIEMPIK_01385	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
KOIEMPIK_01386	9.1e-112	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KOIEMPIK_01387	3.93e-59	-	-	-	-	-	-	-	-
KOIEMPIK_01388	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KOIEMPIK_01389	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
KOIEMPIK_01390	1.06e-278	-	-	-	-	-	-	-	-
KOIEMPIK_01391	1.63e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KOIEMPIK_01392	6.71e-80	-	-	-	S	-	-	-	CHY zinc finger
KOIEMPIK_01393	2.48e-226	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KOIEMPIK_01394	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
KOIEMPIK_01395	6.4e-54	-	-	-	-	-	-	-	-
KOIEMPIK_01396	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KOIEMPIK_01397	7.28e-42	-	-	-	-	-	-	-	-
KOIEMPIK_01398	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
KOIEMPIK_01399	2.36e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
KOIEMPIK_01401	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
KOIEMPIK_01402	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
KOIEMPIK_01403	1.08e-243	-	-	-	-	-	-	-	-
KOIEMPIK_01404	1.85e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_01405	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
KOIEMPIK_01406	2.06e-30	-	-	-	-	-	-	-	-
KOIEMPIK_01407	2.14e-117	-	-	-	K	-	-	-	acetyltransferase
KOIEMPIK_01408	1.88e-111	-	-	-	K	-	-	-	GNAT family
KOIEMPIK_01409	8.08e-110	-	-	-	S	-	-	-	ASCH
KOIEMPIK_01410	4.3e-124	-	-	-	K	-	-	-	Cupin domain
KOIEMPIK_01411	5.09e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KOIEMPIK_01412	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_01413	5.58e-181	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_01414	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_01415	1.79e-52	-	-	-	-	-	-	-	-
KOIEMPIK_01416	1.17e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
KOIEMPIK_01417	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_01418	1.79e-100	-	-	-	S	ko:K02348	-	ko00000	GNAT family
KOIEMPIK_01419	3.74e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOIEMPIK_01420	2.04e-73	-	-	-	-	-	-	-	-
KOIEMPIK_01421	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
KOIEMPIK_01422	2.8e-169	-	-	-	-	-	-	-	-
KOIEMPIK_01423	5.01e-226	-	-	-	-	-	-	-	-
KOIEMPIK_01424	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
KOIEMPIK_01425	2.31e-95	-	-	-	M	-	-	-	LysM domain protein
KOIEMPIK_01426	3.42e-76	-	-	-	M	-	-	-	Lysin motif
KOIEMPIK_01427	4.75e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01428	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_01429	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_01430	1.84e-295	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
KOIEMPIK_01431	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
KOIEMPIK_01432	3.39e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
KOIEMPIK_01433	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
KOIEMPIK_01434	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
KOIEMPIK_01435	2.04e-158	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
KOIEMPIK_01436	1.49e-63	-	-	-	-	-	-	-	-
KOIEMPIK_01437	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
KOIEMPIK_01438	7.18e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
KOIEMPIK_01439	2.87e-56	-	-	-	-	-	-	-	-
KOIEMPIK_01440	3.35e-75	-	-	-	-	-	-	-	-
KOIEMPIK_01441	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_01442	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KOIEMPIK_01443	2.42e-65	-	-	-	-	-	-	-	-
KOIEMPIK_01444	1.1e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
KOIEMPIK_01445	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
KOIEMPIK_01446	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_01447	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_01448	1.55e-55	-	-	-	-	-	-	-	-
KOIEMPIK_01449	2.92e-57	-	-	-	-	-	-	-	-
KOIEMPIK_01450	1.15e-152	-	-	-	-	-	-	-	-
KOIEMPIK_01451	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KOIEMPIK_01452	5.2e-156	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_01453	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_01454	9.53e-93	-	-	-	-	-	-	-	-
KOIEMPIK_01455	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KOIEMPIK_01456	1.3e-203	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
KOIEMPIK_01457	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOIEMPIK_01458	4.5e-303	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
KOIEMPIK_01459	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
KOIEMPIK_01460	2.6e-185	-	-	-	-	-	-	-	-
KOIEMPIK_01461	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KOIEMPIK_01462	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_01463	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KOIEMPIK_01464	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
KOIEMPIK_01465	2.21e-56	-	-	-	-	-	-	-	-
KOIEMPIK_01466	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
KOIEMPIK_01467	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
KOIEMPIK_01468	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
KOIEMPIK_01469	1.3e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
KOIEMPIK_01470	1e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
KOIEMPIK_01471	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
KOIEMPIK_01472	1.17e-244	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
KOIEMPIK_01473	1.45e-93	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
KOIEMPIK_01474	1.75e-51	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
KOIEMPIK_01475	8.38e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
KOIEMPIK_01476	6.28e-272	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
KOIEMPIK_01477	2.18e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KOIEMPIK_01478	3.56e-52	-	-	-	-	-	-	-	-
KOIEMPIK_01479	4.99e-296	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_01480	2.8e-161	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
KOIEMPIK_01481	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
KOIEMPIK_01482	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
KOIEMPIK_01483	2.41e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
KOIEMPIK_01484	2.98e-90	-	-	-	-	-	-	-	-
KOIEMPIK_01485	1.22e-125	-	-	-	-	-	-	-	-
KOIEMPIK_01486	7.19e-68	-	-	-	-	-	-	-	-
KOIEMPIK_01487	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KOIEMPIK_01488	2.43e-111	-	-	-	-	-	-	-	-
KOIEMPIK_01489	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
KOIEMPIK_01490	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_01491	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
KOIEMPIK_01492	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KOIEMPIK_01493	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
KOIEMPIK_01494	2.46e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_01495	7.88e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
KOIEMPIK_01496	2.22e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
KOIEMPIK_01497	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOIEMPIK_01498	2.32e-43	ygzD	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
KOIEMPIK_01499	4.02e-90	-	-	-	-	-	-	-	-
KOIEMPIK_01500	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOIEMPIK_01501	5.3e-202	dkgB	-	-	S	-	-	-	reductase
KOIEMPIK_01502	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
KOIEMPIK_01503	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
KOIEMPIK_01504	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KOIEMPIK_01505	2.13e-150	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KOIEMPIK_01506	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
KOIEMPIK_01507	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOIEMPIK_01508	5.08e-74	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOIEMPIK_01509	3.81e-18	-	-	-	-	-	-	-	-
KOIEMPIK_01510	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOIEMPIK_01511	1.46e-206	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
KOIEMPIK_01512	1.81e-15	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
KOIEMPIK_01513	6.33e-46	-	-	-	-	-	-	-	-
KOIEMPIK_01514	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
KOIEMPIK_01515	6.7e-148	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
KOIEMPIK_01516	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KOIEMPIK_01517	1.69e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOIEMPIK_01518	9.25e-103	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
KOIEMPIK_01519	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KOIEMPIK_01520	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KOIEMPIK_01521	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
KOIEMPIK_01523	0.0	-	-	-	M	-	-	-	domain protein
KOIEMPIK_01524	1.41e-158	mleR	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_01525	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KOIEMPIK_01526	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
KOIEMPIK_01527	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
KOIEMPIK_01528	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KOIEMPIK_01529	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
KOIEMPIK_01530	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
KOIEMPIK_01531	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_01532	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
KOIEMPIK_01533	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
KOIEMPIK_01534	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
KOIEMPIK_01535	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
KOIEMPIK_01536	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KOIEMPIK_01537	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
KOIEMPIK_01538	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
KOIEMPIK_01539	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
KOIEMPIK_01540	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_01541	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
KOIEMPIK_01542	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
KOIEMPIK_01543	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
KOIEMPIK_01544	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
KOIEMPIK_01545	1.08e-244	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
KOIEMPIK_01546	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KOIEMPIK_01547	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
KOIEMPIK_01548	3.9e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
KOIEMPIK_01549	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
KOIEMPIK_01550	2.74e-242	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
KOIEMPIK_01551	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_01553	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
KOIEMPIK_01554	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
KOIEMPIK_01555	9.77e-152	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
KOIEMPIK_01556	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
KOIEMPIK_01557	4.07e-216	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_01558	7.14e-185	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
KOIEMPIK_01559	3.37e-115	-	-	-	-	-	-	-	-
KOIEMPIK_01560	3.16e-191	-	-	-	-	-	-	-	-
KOIEMPIK_01561	6.34e-182	-	-	-	-	-	-	-	-
KOIEMPIK_01562	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
KOIEMPIK_01563	3.08e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
KOIEMPIK_01565	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
KOIEMPIK_01566	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_01567	4.46e-191	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
KOIEMPIK_01568	4.2e-264	-	-	-	C	-	-	-	Oxidoreductase
KOIEMPIK_01569	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_01570	6.97e-126	-	-	-	-	-	-	-	-
KOIEMPIK_01571	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
KOIEMPIK_01572	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
KOIEMPIK_01573	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
KOIEMPIK_01574	2.16e-204	morA	-	-	S	-	-	-	reductase
KOIEMPIK_01576	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
KOIEMPIK_01577	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KOIEMPIK_01578	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KOIEMPIK_01579	4.46e-88	-	-	-	K	-	-	-	LytTr DNA-binding domain
KOIEMPIK_01580	1.11e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KOIEMPIK_01581	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KOIEMPIK_01582	9.35e-101	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_01583	1.47e-143	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
KOIEMPIK_01584	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
KOIEMPIK_01585	8.08e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
KOIEMPIK_01586	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
KOIEMPIK_01587	2.44e-127	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
KOIEMPIK_01588	2.81e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOIEMPIK_01589	2.48e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KOIEMPIK_01590	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KOIEMPIK_01591	4.17e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
KOIEMPIK_01592	1.73e-157	-	-	-	-	-	-	-	-
KOIEMPIK_01593	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
KOIEMPIK_01594	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
KOIEMPIK_01595	0.0	-	-	-	L	-	-	-	HIRAN domain
KOIEMPIK_01596	1.02e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
KOIEMPIK_01597	1.97e-259	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
KOIEMPIK_01598	2.68e-143	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KOIEMPIK_01599	3.03e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
KOIEMPIK_01600	1.79e-173	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KOIEMPIK_01601	3.94e-224	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KOIEMPIK_01602	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
KOIEMPIK_01603	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KOIEMPIK_01604	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
KOIEMPIK_01605	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
KOIEMPIK_01606	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
KOIEMPIK_01607	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
KOIEMPIK_01608	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
KOIEMPIK_01609	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
KOIEMPIK_01610	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
KOIEMPIK_01611	3.52e-165	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_01612	1.67e-54	-	-	-	-	-	-	-	-
KOIEMPIK_01613	3.67e-180	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
KOIEMPIK_01614	4.07e-05	-	-	-	-	-	-	-	-
KOIEMPIK_01615	3.42e-180	-	-	-	-	-	-	-	-
KOIEMPIK_01616	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
KOIEMPIK_01617	2.38e-99	-	-	-	-	-	-	-	-
KOIEMPIK_01618	9.06e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
KOIEMPIK_01619	2.58e-214	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KOIEMPIK_01620	1.71e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
KOIEMPIK_01621	3.49e-67	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KOIEMPIK_01622	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
KOIEMPIK_01623	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
KOIEMPIK_01624	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
KOIEMPIK_01625	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
KOIEMPIK_01626	1.9e-79	-	-	-	S	-	-	-	Protein of unknown function
KOIEMPIK_01627	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
KOIEMPIK_01628	0.0	fusA1	-	-	J	-	-	-	elongation factor G
KOIEMPIK_01629	1.34e-151	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KOIEMPIK_01630	1.67e-220	-	-	-	K	-	-	-	WYL domain
KOIEMPIK_01631	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
KOIEMPIK_01632	1.65e-106	-	-	-	S	-	-	-	ASCH
KOIEMPIK_01633	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
KOIEMPIK_01634	3.97e-174	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KOIEMPIK_01635	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
KOIEMPIK_01636	6.27e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KOIEMPIK_01637	3.83e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
KOIEMPIK_01638	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
KOIEMPIK_01639	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
KOIEMPIK_01640	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
KOIEMPIK_01641	4.06e-211	-	-	-	S	-	-	-	KR domain
KOIEMPIK_01642	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KOIEMPIK_01643	2.49e-95	-	-	-	C	-	-	-	FMN binding
KOIEMPIK_01644	4.28e-83	-	-	-	K	-	-	-	LysR family
KOIEMPIK_01645	8.51e-107	-	-	-	K	-	-	-	LysR family
KOIEMPIK_01646	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
KOIEMPIK_01647	0.0	-	-	-	C	-	-	-	FMN_bind
KOIEMPIK_01648	5.25e-149	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
KOIEMPIK_01649	2.02e-85	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
KOIEMPIK_01650	2.24e-155	pnb	-	-	C	-	-	-	nitroreductase
KOIEMPIK_01651	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
KOIEMPIK_01652	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
KOIEMPIK_01653	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_01654	1.74e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KOIEMPIK_01655	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
KOIEMPIK_01656	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
KOIEMPIK_01657	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
KOIEMPIK_01658	1.02e-312	yycH	-	-	S	-	-	-	YycH protein
KOIEMPIK_01659	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
KOIEMPIK_01660	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
KOIEMPIK_01662	2.54e-50	-	-	-	-	-	-	-	-
KOIEMPIK_01663	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
KOIEMPIK_01664	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
KOIEMPIK_01665	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
KOIEMPIK_01666	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
KOIEMPIK_01667	2.4e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KOIEMPIK_01669	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KOIEMPIK_01670	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOIEMPIK_01671	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
KOIEMPIK_01672	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
KOIEMPIK_01673	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KOIEMPIK_01674	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KOIEMPIK_01675	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
KOIEMPIK_01677	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KOIEMPIK_01678	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOIEMPIK_01679	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_01680	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
KOIEMPIK_01681	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
KOIEMPIK_01682	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
KOIEMPIK_01683	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KOIEMPIK_01684	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOIEMPIK_01685	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
KOIEMPIK_01686	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOIEMPIK_01687	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOIEMPIK_01688	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KOIEMPIK_01689	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
KOIEMPIK_01690	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KOIEMPIK_01691	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KOIEMPIK_01692	4.62e-20	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
KOIEMPIK_01693	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KOIEMPIK_01694	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOIEMPIK_01695	5.56e-172	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
KOIEMPIK_01696	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KOIEMPIK_01697	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KOIEMPIK_01698	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
KOIEMPIK_01699	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KOIEMPIK_01701	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_01702	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KOIEMPIK_01704	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
KOIEMPIK_01705	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
KOIEMPIK_01706	4.02e-203	degV1	-	-	S	-	-	-	DegV family
KOIEMPIK_01707	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_01708	1e-180	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
KOIEMPIK_01709	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
KOIEMPIK_01710	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
KOIEMPIK_01711	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
KOIEMPIK_01712	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
KOIEMPIK_01713	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
KOIEMPIK_01714	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOIEMPIK_01715	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KOIEMPIK_01716	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
KOIEMPIK_01717	2.21e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
KOIEMPIK_01718	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
KOIEMPIK_01719	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
KOIEMPIK_01720	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
KOIEMPIK_01721	5.04e-234	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
KOIEMPIK_01722	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KOIEMPIK_01723	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KOIEMPIK_01724	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_01725	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KOIEMPIK_01726	1.14e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KOIEMPIK_01728	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
KOIEMPIK_01729	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
KOIEMPIK_01730	9.62e-19	-	-	-	-	-	-	-	-
KOIEMPIK_01731	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KOIEMPIK_01732	4.29e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KOIEMPIK_01733	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
KOIEMPIK_01734	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
KOIEMPIK_01735	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
KOIEMPIK_01736	1.06e-16	-	-	-	-	-	-	-	-
KOIEMPIK_01737	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
KOIEMPIK_01738	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
KOIEMPIK_01739	1.13e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
KOIEMPIK_01740	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KOIEMPIK_01741	3.44e-262	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
KOIEMPIK_01742	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KOIEMPIK_01743	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
KOIEMPIK_01744	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KOIEMPIK_01745	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
KOIEMPIK_01746	6.83e-133	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
KOIEMPIK_01747	1.73e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KOIEMPIK_01748	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KOIEMPIK_01749	3.05e-161	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
KOIEMPIK_01750	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOIEMPIK_01751	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KOIEMPIK_01752	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KOIEMPIK_01753	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
KOIEMPIK_01754	4.53e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KOIEMPIK_01755	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOIEMPIK_01756	6.42e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOIEMPIK_01757	1.04e-60	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
KOIEMPIK_01758	1.43e-306	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KOIEMPIK_01759	1.68e-146	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KOIEMPIK_01760	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KOIEMPIK_01761	7.09e-184	yxeH	-	-	S	-	-	-	hydrolase
KOIEMPIK_01762	2.83e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KOIEMPIK_01764	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
KOIEMPIK_01765	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
KOIEMPIK_01766	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
KOIEMPIK_01767	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
KOIEMPIK_01768	1.85e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KOIEMPIK_01769	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_01770	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_01771	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_01772	8.75e-199	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KOIEMPIK_01773	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_01774	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_01775	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KOIEMPIK_01776	1.69e-202	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
KOIEMPIK_01777	6.89e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KOIEMPIK_01778	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_01779	5.44e-174	-	-	-	K	-	-	-	UTRA domain
KOIEMPIK_01780	2.53e-198	estA	-	-	S	-	-	-	Putative esterase
KOIEMPIK_01781	2.09e-83	-	-	-	-	-	-	-	-
KOIEMPIK_01782	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KOIEMPIK_01783	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
KOIEMPIK_01784	5.56e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
KOIEMPIK_01785	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
KOIEMPIK_01786	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOIEMPIK_01787	1.2e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOIEMPIK_01788	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KOIEMPIK_01789	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
KOIEMPIK_01790	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOIEMPIK_01791	2.11e-171	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KOIEMPIK_01792	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOIEMPIK_01793	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KOIEMPIK_01794	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
KOIEMPIK_01795	1.48e-247	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
KOIEMPIK_01796	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KOIEMPIK_01797	7.07e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
KOIEMPIK_01798	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KOIEMPIK_01799	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
KOIEMPIK_01800	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
KOIEMPIK_01801	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
KOIEMPIK_01802	3.32e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KOIEMPIK_01803	2.97e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
KOIEMPIK_01804	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
KOIEMPIK_01805	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KOIEMPIK_01806	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
KOIEMPIK_01807	3.9e-143	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
KOIEMPIK_01808	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
KOIEMPIK_01809	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
KOIEMPIK_01810	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KOIEMPIK_01811	5.63e-293	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
KOIEMPIK_01812	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KOIEMPIK_01813	1.11e-240	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
KOIEMPIK_01814	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
KOIEMPIK_01815	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
KOIEMPIK_01816	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KOIEMPIK_01817	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
KOIEMPIK_01818	1.6e-139	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KOIEMPIK_01819	4.03e-283	-	-	-	S	-	-	-	associated with various cellular activities
KOIEMPIK_01820	1.87e-316	-	-	-	S	-	-	-	Putative metallopeptidase domain
KOIEMPIK_01821	1.03e-65	-	-	-	-	-	-	-	-
KOIEMPIK_01822	1.72e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
KOIEMPIK_01823	7.83e-60	-	-	-	-	-	-	-	-
KOIEMPIK_01824	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_01825	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_01826	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
KOIEMPIK_01827	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
KOIEMPIK_01828	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
KOIEMPIK_01829	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KOIEMPIK_01830	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
KOIEMPIK_01831	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
KOIEMPIK_01832	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
KOIEMPIK_01833	2.03e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
KOIEMPIK_01834	1.01e-26	-	-	-	-	-	-	-	-
KOIEMPIK_01835	6.85e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
KOIEMPIK_01836	9.52e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
KOIEMPIK_01837	9.44e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
KOIEMPIK_01838	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
KOIEMPIK_01839	2.93e-234	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KOIEMPIK_01840	3.04e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
KOIEMPIK_01841	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KOIEMPIK_01842	1.24e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
KOIEMPIK_01843	8.52e-130	-	-	-	K	-	-	-	transcriptional regulator
KOIEMPIK_01844	7.98e-205	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
KOIEMPIK_01845	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
KOIEMPIK_01846	4.99e-52	-	-	-	-	-	-	-	-
KOIEMPIK_01847	6.97e-68	-	-	-	-	-	-	-	-
KOIEMPIK_01848	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_01850	9.96e-82	-	-	-	-	-	-	-	-
KOIEMPIK_01851	6.18e-71	-	-	-	-	-	-	-	-
KOIEMPIK_01852	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
KOIEMPIK_01853	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
KOIEMPIK_01854	4.45e-38	-	-	-	-	-	-	-	-
KOIEMPIK_01855	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
KOIEMPIK_01856	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_01857	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KOIEMPIK_01858	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
KOIEMPIK_01859	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_01860	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KOIEMPIK_01861	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_01862	2.41e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
KOIEMPIK_01863	1.58e-66	-	-	-	-	-	-	-	-
KOIEMPIK_01864	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
KOIEMPIK_01865	4.88e-117	ymdB	-	-	S	-	-	-	Macro domain protein
KOIEMPIK_01866	5.43e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KOIEMPIK_01867	1.21e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
KOIEMPIK_01868	2.93e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
KOIEMPIK_01869	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
KOIEMPIK_01870	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
KOIEMPIK_01871	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KOIEMPIK_01872	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KOIEMPIK_01873	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
KOIEMPIK_01874	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
KOIEMPIK_01875	1.18e-98	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
KOIEMPIK_01876	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KOIEMPIK_01877	2.52e-282	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
KOIEMPIK_01878	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
KOIEMPIK_01879	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
KOIEMPIK_01880	2.55e-65	-	-	-	-	-	-	-	-
KOIEMPIK_01881	7.21e-35	-	-	-	-	-	-	-	-
KOIEMPIK_01882	1.45e-313	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
KOIEMPIK_01883	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
KOIEMPIK_01884	4.26e-54	-	-	-	-	-	-	-	-
KOIEMPIK_01885	4.83e-98	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
KOIEMPIK_01886	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KOIEMPIK_01887	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
KOIEMPIK_01888	2.55e-145	-	-	-	S	-	-	-	VIT family
KOIEMPIK_01889	2.66e-155	-	-	-	S	-	-	-	membrane
KOIEMPIK_01890	1.63e-203	-	-	-	EG	-	-	-	EamA-like transporter family
KOIEMPIK_01891	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
KOIEMPIK_01892	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
KOIEMPIK_01893	4.79e-21	-	-	-	-	-	-	-	-
KOIEMPIK_01894	2.27e-74	-	-	-	-	-	-	-	-
KOIEMPIK_01895	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KOIEMPIK_01896	1.36e-112	-	-	-	-	-	-	-	-
KOIEMPIK_01897	2.11e-82	-	-	-	-	-	-	-	-
KOIEMPIK_01898	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
KOIEMPIK_01899	1.7e-70	-	-	-	-	-	-	-	-
KOIEMPIK_01900	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
KOIEMPIK_01901	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
KOIEMPIK_01902	4.31e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
KOIEMPIK_01903	1.36e-209	-	-	-	GM	-	-	-	NmrA-like family
KOIEMPIK_01904	1.65e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
KOIEMPIK_01905	2.65e-215	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_01906	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KOIEMPIK_01907	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
KOIEMPIK_01908	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
KOIEMPIK_01909	5.84e-255	glmS2	-	-	M	-	-	-	SIS domain
KOIEMPIK_01910	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KOIEMPIK_01911	3.19e-283	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
KOIEMPIK_01912	2.82e-161	-	-	-	S	-	-	-	YjbR
KOIEMPIK_01914	0.0	cadA	-	-	P	-	-	-	P-type ATPase
KOIEMPIK_01915	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
KOIEMPIK_01916	1.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
KOIEMPIK_01917	4.29e-101	-	-	-	-	-	-	-	-
KOIEMPIK_01918	5.09e-51	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
KOIEMPIK_01919	2.42e-127	-	-	-	FG	-	-	-	HIT domain
KOIEMPIK_01920	7.39e-224	ydhF	-	-	S	-	-	-	Aldo keto reductase
KOIEMPIK_01921	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
KOIEMPIK_01922	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOIEMPIK_01923	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
KOIEMPIK_01924	4.41e-248	-	-	-	V	-	-	-	Beta-lactamase
KOIEMPIK_01925	3.74e-125	-	-	-	V	-	-	-	VanZ like family
KOIEMPIK_01926	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
KOIEMPIK_01927	4.54e-54	-	-	-	-	-	-	-	-
KOIEMPIK_01929	4.41e-316	-	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_01930	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KOIEMPIK_01931	4.26e-109	cvpA	-	-	S	-	-	-	Colicin V production protein
KOIEMPIK_01932	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KOIEMPIK_01933	1.3e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KOIEMPIK_01934	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
KOIEMPIK_01935	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KOIEMPIK_01936	3.47e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
KOIEMPIK_01937	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
KOIEMPIK_01938	1.59e-123	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
KOIEMPIK_01939	8.03e-28	-	-	-	-	-	-	-	-
KOIEMPIK_01941	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KOIEMPIK_01942	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
KOIEMPIK_01943	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
KOIEMPIK_01944	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
KOIEMPIK_01945	2.8e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
KOIEMPIK_01946	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
KOIEMPIK_01947	5.85e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
KOIEMPIK_01948	2.19e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
KOIEMPIK_01949	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOIEMPIK_01950	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
KOIEMPIK_01952	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
KOIEMPIK_01953	7.97e-108	-	-	-	-	-	-	-	-
KOIEMPIK_01954	2.45e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KOIEMPIK_01955	1.12e-186	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
KOIEMPIK_01956	1.18e-82	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_01958	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KOIEMPIK_01959	2.5e-188	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KOIEMPIK_01960	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KOIEMPIK_01961	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KOIEMPIK_01962	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KOIEMPIK_01963	8.36e-72	-	-	-	S	-	-	-	Enterocin A Immunity
KOIEMPIK_01964	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
KOIEMPIK_01965	3.51e-252	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
KOIEMPIK_01966	3.85e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
KOIEMPIK_01967	2.85e-210	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
KOIEMPIK_01968	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
KOIEMPIK_01969	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
KOIEMPIK_01970	1.03e-34	-	-	-	-	-	-	-	-
KOIEMPIK_01971	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
KOIEMPIK_01972	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
KOIEMPIK_01973	4.14e-84	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
KOIEMPIK_01974	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_01975	4.59e-216	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
KOIEMPIK_01976	3.08e-47	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
KOIEMPIK_01977	7.43e-77	-	-	-	S	-	-	-	Enterocin A Immunity
KOIEMPIK_01978	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
KOIEMPIK_01979	1.16e-135	-	-	-	-	-	-	-	-
KOIEMPIK_01980	8.44e-304	-	-	-	S	-	-	-	module of peptide synthetase
KOIEMPIK_01981	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KOIEMPIK_01983	1.25e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
KOIEMPIK_01984	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_01985	1.43e-44	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_01986	1.25e-198	-	-	-	GM	-	-	-	NmrA-like family
KOIEMPIK_01987	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
KOIEMPIK_01988	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOIEMPIK_01989	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
KOIEMPIK_01990	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KOIEMPIK_01991	1.35e-154	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
KOIEMPIK_01992	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
KOIEMPIK_01993	1.29e-115	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
KOIEMPIK_01994	3.03e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
KOIEMPIK_01995	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
KOIEMPIK_01996	6.26e-101	-	-	-	-	-	-	-	-
KOIEMPIK_01997	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOIEMPIK_01998	5.06e-152	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_01999	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
KOIEMPIK_02000	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
KOIEMPIK_02001	6.39e-234	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
KOIEMPIK_02002	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
KOIEMPIK_02003	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_02004	9.68e-202	-	-	-	S	-	-	-	Putative adhesin
KOIEMPIK_02005	6.03e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
KOIEMPIK_02006	8.52e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
KOIEMPIK_02007	8.83e-127	-	-	-	KT	-	-	-	response to antibiotic
KOIEMPIK_02008	3.6e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KOIEMPIK_02009	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02010	8.59e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_02011	6.12e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
KOIEMPIK_02012	5.69e-300	-	-	-	EK	-	-	-	Aminotransferase, class I
KOIEMPIK_02013	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_02014	3.66e-189	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_02015	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KOIEMPIK_02016	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
KOIEMPIK_02017	4.27e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
KOIEMPIK_02018	7.39e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KOIEMPIK_02019	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
KOIEMPIK_02020	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
KOIEMPIK_02021	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
KOIEMPIK_02022	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KOIEMPIK_02023	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
KOIEMPIK_02024	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KOIEMPIK_02025	1.91e-207	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KOIEMPIK_02026	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
KOIEMPIK_02027	1.14e-159	vanR	-	-	K	-	-	-	response regulator
KOIEMPIK_02028	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
KOIEMPIK_02029	3.61e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
KOIEMPIK_02030	1.66e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
KOIEMPIK_02031	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
KOIEMPIK_02032	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
KOIEMPIK_02033	9.65e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KOIEMPIK_02034	5.01e-71	-	-	-	-	-	-	-	-
KOIEMPIK_02036	2.29e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KOIEMPIK_02037	1.01e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
KOIEMPIK_02038	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
KOIEMPIK_02039	2.27e-257	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
KOIEMPIK_02040	1.41e-211	-	-	-	-	-	-	-	-
KOIEMPIK_02041	4.45e-296	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
KOIEMPIK_02042	5.02e-151	-	-	-	-	-	-	-	-
KOIEMPIK_02043	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
KOIEMPIK_02044	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
KOIEMPIK_02045	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOIEMPIK_02046	1.94e-153	-	-	-	Q	-	-	-	Methyltransferase domain
KOIEMPIK_02047	5.02e-52	-	-	-	-	-	-	-	-
KOIEMPIK_02048	1.11e-81	-	-	-	S	-	-	-	PFAM Metallo-beta-lactamase superfamily
KOIEMPIK_02049	6.11e-09	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
KOIEMPIK_02050	1.67e-148	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
KOIEMPIK_02051	5.82e-46	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_02052	6.52e-69	yoaZ	-	-	S	-	-	-	intracellular protease amidase
KOIEMPIK_02053	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_02054	1.4e-199	is18	-	-	L	-	-	-	Integrase core domain
KOIEMPIK_02055	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
KOIEMPIK_02056	6.46e-79	-	-	-	L	ko:K19173	-	ko00000,ko02048	COG0433 Predicted ATPase
KOIEMPIK_02057	2.61e-66	-	-	-	-	ko:K19174	-	ko00000,ko02048	-
KOIEMPIK_02058	5.59e-293	-	-	-	S	ko:K19175	-	ko00000,ko02048	Domain of unknown function DUF87
KOIEMPIK_02059	2.67e-265	-	-	-	S	-	-	-	Membrane
KOIEMPIK_02060	2.35e-56	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
KOIEMPIK_02062	1.44e-16	-	-	-	S	-	-	-	Mor transcription activator family
KOIEMPIK_02063	1.78e-13	-	-	-	-	-	-	-	-
KOIEMPIK_02064	1.51e-30	-	-	-	S	-	-	-	Mor transcription activator family
KOIEMPIK_02065	9.76e-39	-	-	-	-	-	-	-	-
KOIEMPIK_02067	1.42e-100	-	-	-	-	-	-	-	-
KOIEMPIK_02068	8.82e-45	-	-	-	-	-	-	-	-
KOIEMPIK_02071	1.71e-170	int3	-	-	L	-	-	-	Phage integrase SAM-like domain
KOIEMPIK_02072	1.61e-12	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	Reverse transcriptase (RNA-dependent DNA polymerase)
KOIEMPIK_02074	4.13e-42	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KOIEMPIK_02075	6.79e-53	-	-	-	-	-	-	-	-
KOIEMPIK_02077	8.53e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KOIEMPIK_02078	1.34e-05	-	-	-	L	ko:K07483	-	ko00000	transposase activity
KOIEMPIK_02079	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_02080	2.52e-85	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
KOIEMPIK_02081	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
KOIEMPIK_02082	8.89e-101	-	-	-	GM	-	-	-	SnoaL-like domain
KOIEMPIK_02083	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_02084	4.01e-142	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KOIEMPIK_02085	3.29e-154	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
KOIEMPIK_02086	2.4e-112	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
KOIEMPIK_02087	5.49e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
KOIEMPIK_02088	6.14e-65	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_02089	2.06e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_02090	7.55e-76	-	-	-	-	-	-	-	-
KOIEMPIK_02091	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KOIEMPIK_02092	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
KOIEMPIK_02093	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
KOIEMPIK_02094	1.91e-280	-	-	-	S	-	-	-	Membrane
KOIEMPIK_02095	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KOIEMPIK_02096	2.61e-64	sgaB	2.7.1.194, 2.7.1.200	-	G	ko:K02774,ko:K02822,ko:K03475	ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KOIEMPIK_02097	8.26e-307	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
KOIEMPIK_02098	0.0	-	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KOIEMPIK_02099	1.53e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
KOIEMPIK_02100	0.0	-	-	-	G	ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757	ko00010,ko02060,map00010,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
KOIEMPIK_02101	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_02102	1.43e-186	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
KOIEMPIK_02104	1.85e-41	-	-	-	-	-	-	-	-
KOIEMPIK_02105	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
KOIEMPIK_02106	0.0	-	-	-	S	-	-	-	MucBP domain
KOIEMPIK_02107	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
KOIEMPIK_02108	4.71e-209	-	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_02109	7.53e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
KOIEMPIK_02110	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KOIEMPIK_02111	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOIEMPIK_02112	5.65e-151	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_02113	1.12e-253	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
KOIEMPIK_02114	4.49e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_02115	4.28e-233	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KOIEMPIK_02116	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
KOIEMPIK_02117	3.86e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_02118	1.83e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
KOIEMPIK_02119	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
KOIEMPIK_02120	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_02121	3.89e-210	-	-	-	GM	-	-	-	NmrA-like family
KOIEMPIK_02122	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_02123	1.58e-217	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOIEMPIK_02124	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOIEMPIK_02125	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
KOIEMPIK_02126	7.05e-219	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
KOIEMPIK_02127	2.64e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_02128	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
KOIEMPIK_02129	1.97e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
KOIEMPIK_02130	2.19e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KOIEMPIK_02131	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
KOIEMPIK_02132	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_02133	3.27e-170	-	-	-	S	-	-	-	KR domain
KOIEMPIK_02134	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KOIEMPIK_02135	2.7e-61	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
KOIEMPIK_02136	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
KOIEMPIK_02137	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
KOIEMPIK_02138	4.4e-215	-	-	-	GM	-	-	-	NmrA-like family
KOIEMPIK_02139	3.21e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
KOIEMPIK_02140	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KOIEMPIK_02141	4.63e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
KOIEMPIK_02142	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
KOIEMPIK_02143	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
KOIEMPIK_02144	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_02145	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
KOIEMPIK_02146	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
KOIEMPIK_02147	4.13e-157	-	-	-	-	-	-	-	-
KOIEMPIK_02148	8.15e-306	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
KOIEMPIK_02149	1.47e-83	-	-	-	-	-	-	-	-
KOIEMPIK_02150	4.48e-130	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_02151	2.63e-242	ynjC	-	-	S	-	-	-	Cell surface protein
KOIEMPIK_02152	1.36e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
KOIEMPIK_02153	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KOIEMPIK_02154	1.33e-225	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
KOIEMPIK_02155	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_02156	2.85e-243	-	-	-	S	-	-	-	Cell surface protein
KOIEMPIK_02157	2.69e-99	-	-	-	-	-	-	-	-
KOIEMPIK_02158	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_02159	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
KOIEMPIK_02160	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
KOIEMPIK_02161	3.28e-180	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_02162	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KOIEMPIK_02163	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
KOIEMPIK_02164	2.04e-56	-	-	-	S	-	-	-	Cupredoxin-like domain
KOIEMPIK_02165	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
KOIEMPIK_02166	1.31e-269	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
KOIEMPIK_02167	1.41e-199	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
KOIEMPIK_02168	1.16e-49	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
KOIEMPIK_02169	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
KOIEMPIK_02170	0.0	-	-	-	E	-	-	-	Amino Acid
KOIEMPIK_02171	1.01e-184	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KOIEMPIK_02172	3.27e-91	-	-	-	-	-	-	-	-
KOIEMPIK_02174	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
KOIEMPIK_02175	2.09e-286	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
KOIEMPIK_02176	1.65e-21	-	-	-	-	-	-	-	-
KOIEMPIK_02177	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02178	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_02179	2.31e-277	-	-	-	-	-	-	-	-
KOIEMPIK_02180	8.04e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_02181	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
KOIEMPIK_02182	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
KOIEMPIK_02183	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
KOIEMPIK_02184	1.17e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
KOIEMPIK_02185	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_02186	3.79e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
KOIEMPIK_02187	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_02188	4.33e-95	-	-	-	-	-	-	-	-
KOIEMPIK_02189	8.21e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
KOIEMPIK_02190	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
KOIEMPIK_02191	5.23e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KOIEMPIK_02192	6.14e-282	-	-	-	T	-	-	-	diguanylate cyclase
KOIEMPIK_02193	1.35e-155	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
KOIEMPIK_02194	3.57e-120	-	-	-	-	-	-	-	-
KOIEMPIK_02195	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
KOIEMPIK_02196	1.58e-72	nudA	-	-	S	-	-	-	ASCH
KOIEMPIK_02197	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
KOIEMPIK_02198	7.68e-45	-	-	-	M	-	-	-	Lysin motif
KOIEMPIK_02199	1.43e-56	-	-	-	M	-	-	-	Lysin motif
KOIEMPIK_02200	4.61e-101	-	-	-	M	-	-	-	LysM domain
KOIEMPIK_02201	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_02202	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
KOIEMPIK_02203	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_02204	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOIEMPIK_02205	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KOIEMPIK_02206	2.26e-99	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KOIEMPIK_02207	8.23e-41	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_02208	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_02209	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_02210	1.21e-73	-	-	-	-	-	-	-	-
KOIEMPIK_02211	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
KOIEMPIK_02212	4.8e-83	-	-	-	-	-	-	-	-
KOIEMPIK_02213	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
KOIEMPIK_02214	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02215	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
KOIEMPIK_02216	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
KOIEMPIK_02217	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
KOIEMPIK_02218	7.03e-62	-	-	-	-	-	-	-	-
KOIEMPIK_02219	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
KOIEMPIK_02220	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
KOIEMPIK_02221	4.08e-158	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KOIEMPIK_02222	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
KOIEMPIK_02223	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
KOIEMPIK_02224	1.15e-43	-	-	-	-	-	-	-	-
KOIEMPIK_02226	4.23e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
KOIEMPIK_02227	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
KOIEMPIK_02228	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
KOIEMPIK_02229	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
KOIEMPIK_02230	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_02231	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
KOIEMPIK_02232	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_02233	2.62e-240	-	-	-	S	-	-	-	Cell surface protein
KOIEMPIK_02234	1.4e-82	-	-	-	-	-	-	-	-
KOIEMPIK_02235	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_02236	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_02237	4.78e-197	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KOIEMPIK_02238	6.24e-152	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
KOIEMPIK_02239	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KOIEMPIK_02240	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
KOIEMPIK_02241	5.24e-124	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
KOIEMPIK_02242	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
KOIEMPIK_02243	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
KOIEMPIK_02244	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
KOIEMPIK_02245	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
KOIEMPIK_02246	3.53e-227	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
KOIEMPIK_02247	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
KOIEMPIK_02248	2.82e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
KOIEMPIK_02249	6.34e-301	-	-	-	M	-	-	-	Collagen binding domain
KOIEMPIK_02250	0.0	-	-	-	I	-	-	-	acetylesterase activity
KOIEMPIK_02251	4.07e-232	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
KOIEMPIK_02252	8.58e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
KOIEMPIK_02253	4.29e-50	-	-	-	-	-	-	-	-
KOIEMPIK_02255	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
KOIEMPIK_02256	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
KOIEMPIK_02257	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
KOIEMPIK_02258	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
KOIEMPIK_02259	5.12e-212	-	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_02260	1.84e-134	-	-	-	-	-	-	-	-
KOIEMPIK_02261	3.7e-30	-	-	-	-	-	-	-	-
KOIEMPIK_02262	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOIEMPIK_02263	1.59e-243	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KOIEMPIK_02264	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
KOIEMPIK_02265	2.59e-107	-	-	-	-	-	-	-	-
KOIEMPIK_02266	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
KOIEMPIK_02267	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KOIEMPIK_02268	2.82e-163	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
KOIEMPIK_02269	2.05e-279	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
KOIEMPIK_02270	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KOIEMPIK_02271	2e-52	-	-	-	S	-	-	-	Cytochrome B5
KOIEMPIK_02272	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_02273	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
KOIEMPIK_02274	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
KOIEMPIK_02275	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
KOIEMPIK_02276	4.03e-297	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
KOIEMPIK_02277	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
KOIEMPIK_02278	1.44e-226	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
KOIEMPIK_02279	2.78e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KOIEMPIK_02280	2e-266	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KOIEMPIK_02281	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
KOIEMPIK_02282	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
KOIEMPIK_02283	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
KOIEMPIK_02284	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
KOIEMPIK_02285	2.34e-284	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
KOIEMPIK_02286	6.3e-169	-	-	-	M	-	-	-	Phosphotransferase enzyme family
KOIEMPIK_02287	7.2e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KOIEMPIK_02288	9.05e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_02289	1.3e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
KOIEMPIK_02290	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KOIEMPIK_02291	3.09e-141	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
KOIEMPIK_02292	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
KOIEMPIK_02295	3.04e-312	-	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_02296	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_02297	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
KOIEMPIK_02299	1e-246	-	-	-	C	-	-	-	Aldo/keto reductase family
KOIEMPIK_02300	1.86e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
KOIEMPIK_02301	9.49e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
KOIEMPIK_02302	9.15e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
KOIEMPIK_02303	5.69e-80	-	-	-	-	-	-	-	-
KOIEMPIK_02304	7.47e-164	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KOIEMPIK_02305	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
KOIEMPIK_02306	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
KOIEMPIK_02307	2.21e-46	-	-	-	-	-	-	-	-
KOIEMPIK_02308	1.12e-117	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
KOIEMPIK_02309	1.81e-94	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
KOIEMPIK_02310	9.34e-30	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
KOIEMPIK_02311	5.55e-106	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_02312	2.35e-175	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
KOIEMPIK_02313	7.42e-177	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KOIEMPIK_02314	5.09e-167	-	-	-	C	-	-	-	Aldo keto reductase
KOIEMPIK_02315	2.11e-148	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_02316	2e-27	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_02317	5.16e-32	-	-	-	C	-	-	-	Flavodoxin
KOIEMPIK_02319	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_02320	3.9e-138	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KOIEMPIK_02321	3.52e-109	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_02322	1.96e-119	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
KOIEMPIK_02323	9.71e-161	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
KOIEMPIK_02324	1.64e-95	-	-	-	C	-	-	-	Flavodoxin
KOIEMPIK_02325	3.56e-107	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KOIEMPIK_02326	1.15e-179	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KOIEMPIK_02327	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
KOIEMPIK_02328	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
KOIEMPIK_02329	1.46e-133	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_02330	7.79e-203	-	-	-	K	-	-	-	LysR substrate binding domain
KOIEMPIK_02331	4.39e-88	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
KOIEMPIK_02332	2.22e-144	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
KOIEMPIK_02333	1.63e-63	-	-	-	-	-	-	-	-
KOIEMPIK_02334	9.76e-50	-	-	-	-	-	-	-	-
KOIEMPIK_02335	6.25e-112	yvbK	-	-	K	-	-	-	GNAT family
KOIEMPIK_02336	8.4e-112	-	-	-	-	-	-	-	-
KOIEMPIK_02337	2.15e-144	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KOIEMPIK_02338	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
KOIEMPIK_02339	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KOIEMPIK_02340	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KOIEMPIK_02342	4.97e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02343	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KOIEMPIK_02344	1.07e-301	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
KOIEMPIK_02345	1.27e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
KOIEMPIK_02346	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
KOIEMPIK_02347	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
KOIEMPIK_02348	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_02349	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
KOIEMPIK_02350	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02351	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
KOIEMPIK_02352	7.51e-77	-	-	-	M	-	-	-	LysM domain
KOIEMPIK_02354	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KOIEMPIK_02355	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
KOIEMPIK_02356	2.06e-194	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
KOIEMPIK_02357	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
KOIEMPIK_02358	5e-130	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KOIEMPIK_02359	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
KOIEMPIK_02360	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
KOIEMPIK_02361	1.46e-162	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
KOIEMPIK_02362	1.28e-75	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KOIEMPIK_02363	3.71e-168	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KOIEMPIK_02364	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
KOIEMPIK_02365	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
KOIEMPIK_02366	2.1e-114	-	-	-	S	-	-	-	Membrane
KOIEMPIK_02367	1.14e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KOIEMPIK_02368	1.02e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
KOIEMPIK_02369	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
KOIEMPIK_02370	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
KOIEMPIK_02371	1.18e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02372	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
KOIEMPIK_02373	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
KOIEMPIK_02374	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KOIEMPIK_02375	1.46e-49	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_02376	8.28e-127	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_02377	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
KOIEMPIK_02378	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KOIEMPIK_02379	3.84e-185	-	-	-	S	-	-	-	Peptidase_C39 like family
KOIEMPIK_02380	2.18e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KOIEMPIK_02381	1.27e-143	-	-	-	-	-	-	-	-
KOIEMPIK_02382	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOIEMPIK_02383	1.97e-110	-	-	-	S	-	-	-	Pfam:DUF3816
KOIEMPIK_02384	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
KOIEMPIK_02386	1.3e-209	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_02387	5.11e-208	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
KOIEMPIK_02388	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
KOIEMPIK_02389	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
KOIEMPIK_02390	0.0	ycaM	-	-	E	-	-	-	amino acid
KOIEMPIK_02391	2.1e-165	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
KOIEMPIK_02392	4.3e-44	-	-	-	-	-	-	-	-
KOIEMPIK_02393	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
KOIEMPIK_02394	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
KOIEMPIK_02395	2.35e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
KOIEMPIK_02396	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
KOIEMPIK_02397	1.99e-115	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
KOIEMPIK_02398	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KOIEMPIK_02399	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
KOIEMPIK_02400	1.51e-235	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KOIEMPIK_02401	5.06e-196	-	-	-	S	-	-	-	hydrolase
KOIEMPIK_02402	7.63e-107	-	-	-	-	-	-	-	-
KOIEMPIK_02403	1.44e-155	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
KOIEMPIK_02404	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
KOIEMPIK_02405	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
KOIEMPIK_02406	1.31e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
KOIEMPIK_02407	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
KOIEMPIK_02408	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_02409	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
KOIEMPIK_02410	2.48e-315	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
KOIEMPIK_02411	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
KOIEMPIK_02412	9.76e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_02413	2.13e-152	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_02414	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOIEMPIK_02415	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
KOIEMPIK_02416	6.73e-287	-	-	-	EGP	-	-	-	Transmembrane secretion effector
KOIEMPIK_02417	4.43e-294	-	-	-	S	-	-	-	Sterol carrier protein domain
KOIEMPIK_02418	9.97e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
KOIEMPIK_02419	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
KOIEMPIK_02420	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
KOIEMPIK_02421	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
KOIEMPIK_02422	2.28e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
KOIEMPIK_02423	2.05e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KOIEMPIK_02424	2.96e-41	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
KOIEMPIK_02425	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KOIEMPIK_02426	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
KOIEMPIK_02427	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
KOIEMPIK_02429	1.21e-69	-	-	-	-	-	-	-	-
KOIEMPIK_02430	1.52e-151	-	-	-	-	-	-	-	-
KOIEMPIK_02431	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
KOIEMPIK_02432	2.49e-298	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
KOIEMPIK_02433	4.79e-13	-	-	-	-	-	-	-	-
KOIEMPIK_02434	1.98e-65	-	-	-	-	-	-	-	-
KOIEMPIK_02435	1.02e-113	-	-	-	-	-	-	-	-
KOIEMPIK_02436	4.69e-94	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
KOIEMPIK_02437	1.08e-47	-	-	-	-	-	-	-	-
KOIEMPIK_02438	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
KOIEMPIK_02439	3.41e-190	-	-	-	-	-	-	-	-
KOIEMPIK_02440	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02441	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
KOIEMPIK_02442	4.76e-56	-	-	-	-	-	-	-	-
KOIEMPIK_02443	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
KOIEMPIK_02444	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02445	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
KOIEMPIK_02446	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_02447	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
KOIEMPIK_02448	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
KOIEMPIK_02449	1.16e-242	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
KOIEMPIK_02450	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
KOIEMPIK_02451	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
KOIEMPIK_02452	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KOIEMPIK_02453	6.77e-269	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KOIEMPIK_02454	3.95e-167	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
KOIEMPIK_02455	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOIEMPIK_02456	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOIEMPIK_02457	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOIEMPIK_02458	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KOIEMPIK_02459	4.04e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
KOIEMPIK_02460	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KOIEMPIK_02461	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
KOIEMPIK_02462	6.66e-281	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
KOIEMPIK_02463	3.16e-158	-	-	-	E	-	-	-	Methionine synthase
KOIEMPIK_02464	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
KOIEMPIK_02465	2.62e-121	-	-	-	-	-	-	-	-
KOIEMPIK_02466	1.25e-199	-	-	-	T	-	-	-	EAL domain
KOIEMPIK_02467	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
KOIEMPIK_02468	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
KOIEMPIK_02469	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
KOIEMPIK_02470	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
KOIEMPIK_02471	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KOIEMPIK_02472	3.5e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
KOIEMPIK_02473	1.38e-309	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KOIEMPIK_02474	4.77e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
KOIEMPIK_02475	1.81e-109	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KOIEMPIK_02476	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
KOIEMPIK_02477	2.99e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KOIEMPIK_02478	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KOIEMPIK_02479	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOIEMPIK_02480	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
KOIEMPIK_02481	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KOIEMPIK_02482	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
KOIEMPIK_02483	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
KOIEMPIK_02484	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
KOIEMPIK_02485	5.73e-208	mleR	-	-	K	-	-	-	LysR family
KOIEMPIK_02486	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
KOIEMPIK_02487	3.59e-26	-	-	-	-	-	-	-	-
KOIEMPIK_02488	4.34e-203	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOIEMPIK_02489	2.91e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
KOIEMPIK_02490	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
KOIEMPIK_02491	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KOIEMPIK_02492	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
KOIEMPIK_02493	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
KOIEMPIK_02494	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_02495	1.17e-270	yttB	-	-	EGP	-	-	-	Major Facilitator
KOIEMPIK_02496	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KOIEMPIK_02497	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
KOIEMPIK_02498	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
KOIEMPIK_02499	2.97e-76	-	-	-	-	-	-	-	-
KOIEMPIK_02500	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
KOIEMPIK_02501	5.4e-80	-	-	-	-	-	-	-	-
KOIEMPIK_02502	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
KOIEMPIK_02503	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
KOIEMPIK_02504	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
KOIEMPIK_02505	6.08e-179	-	-	-	-	-	-	-	-
KOIEMPIK_02506	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KOIEMPIK_02507	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_02508	1.79e-212	-	-	-	S	-	-	-	Putative esterase
KOIEMPIK_02509	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
KOIEMPIK_02510	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
KOIEMPIK_02511	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
KOIEMPIK_02512	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KOIEMPIK_02513	9.66e-97	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
KOIEMPIK_02514	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
KOIEMPIK_02515	2.73e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02516	8.36e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
KOIEMPIK_02517	8.42e-102	uspA3	-	-	T	-	-	-	universal stress protein
KOIEMPIK_02518	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
KOIEMPIK_02519	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
KOIEMPIK_02520	4.15e-78	-	-	-	-	-	-	-	-
KOIEMPIK_02521	4.05e-98	-	-	-	-	-	-	-	-
KOIEMPIK_02522	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
KOIEMPIK_02523	1.57e-71	-	-	-	-	-	-	-	-
KOIEMPIK_02524	3.89e-62	-	-	-	-	-	-	-	-
KOIEMPIK_02525	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
KOIEMPIK_02526	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
KOIEMPIK_02527	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
KOIEMPIK_02528	4.27e-89	-	-	-	-	-	-	-	-
KOIEMPIK_02529	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
KOIEMPIK_02530	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_02531	8.34e-65	-	-	-	-	-	-	-	-
KOIEMPIK_02532	8.36e-74	-	-	-	-	-	-	-	-
KOIEMPIK_02534	7.58e-210	-	-	-	-	-	-	-	-
KOIEMPIK_02535	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
KOIEMPIK_02536	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
KOIEMPIK_02537	3.25e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
KOIEMPIK_02538	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
KOIEMPIK_02539	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
KOIEMPIK_02540	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_02541	2.66e-172	-	-	-	-	-	-	-	-
KOIEMPIK_02542	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
KOIEMPIK_02543	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KOIEMPIK_02544	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
KOIEMPIK_02545	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
KOIEMPIK_02546	5e-227	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
KOIEMPIK_02547	3.24e-147	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
KOIEMPIK_02548	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
KOIEMPIK_02549	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
KOIEMPIK_02550	7.74e-205	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOIEMPIK_02551	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
KOIEMPIK_02552	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
KOIEMPIK_02553	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
KOIEMPIK_02554	1.44e-247	-	-	-	S	-	-	-	domain, Protein
KOIEMPIK_02555	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_02556	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
KOIEMPIK_02557	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
KOIEMPIK_02558	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KOIEMPIK_02559	7.35e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
KOIEMPIK_02560	0.0	-	-	-	M	-	-	-	domain protein
KOIEMPIK_02561	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
KOIEMPIK_02562	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
KOIEMPIK_02563	1.45e-46	-	-	-	-	-	-	-	-
KOIEMPIK_02564	3.17e-235	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KOIEMPIK_02565	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KOIEMPIK_02566	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
KOIEMPIK_02567	1.44e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_02568	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
KOIEMPIK_02569	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
KOIEMPIK_02570	2.09e-212	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KOIEMPIK_02571	3.72e-283	ysaA	-	-	V	-	-	-	RDD family
KOIEMPIK_02572	1.3e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
KOIEMPIK_02573	2.2e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KOIEMPIK_02574	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KOIEMPIK_02575	1.11e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KOIEMPIK_02576	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
KOIEMPIK_02577	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KOIEMPIK_02578	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KOIEMPIK_02579	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KOIEMPIK_02580	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KOIEMPIK_02581	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
KOIEMPIK_02582	3.68e-256	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KOIEMPIK_02583	7.09e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
KOIEMPIK_02584	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
KOIEMPIK_02585	1.11e-201	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
KOIEMPIK_02586	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
KOIEMPIK_02587	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02588	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
KOIEMPIK_02589	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
KOIEMPIK_02590	2.55e-212	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
KOIEMPIK_02591	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
KOIEMPIK_02592	2.04e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
KOIEMPIK_02593	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
KOIEMPIK_02594	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KOIEMPIK_02595	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
KOIEMPIK_02596	3.22e-42	-	-	-	-	-	-	-	-
KOIEMPIK_02597	9.95e-108	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOIEMPIK_02598	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
KOIEMPIK_02599	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
KOIEMPIK_02600	2.21e-275	-	-	-	T	-	-	-	diguanylate cyclase
KOIEMPIK_02601	1.11e-45	-	-	-	-	-	-	-	-
KOIEMPIK_02602	2.29e-48	-	-	-	-	-	-	-	-
KOIEMPIK_02603	4.17e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
KOIEMPIK_02604	1.37e-219	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
KOIEMPIK_02605	4.72e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
KOIEMPIK_02607	2.68e-32	-	-	-	-	-	-	-	-
KOIEMPIK_02608	1.1e-175	-	-	-	F	-	-	-	NUDIX domain
KOIEMPIK_02609	1.96e-273	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
KOIEMPIK_02610	1.53e-63	-	-	-	-	-	-	-	-
KOIEMPIK_02611	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
KOIEMPIK_02613	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
KOIEMPIK_02614	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
KOIEMPIK_02615	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
KOIEMPIK_02616	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
KOIEMPIK_02617	0.0	yclK	-	-	T	-	-	-	Histidine kinase
KOIEMPIK_02618	1.5e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
KOIEMPIK_02619	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
KOIEMPIK_02620	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
KOIEMPIK_02621	2.1e-33	-	-	-	-	-	-	-	-
KOIEMPIK_02622	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02623	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
KOIEMPIK_02624	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
KOIEMPIK_02625	4.63e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02626	2.16e-26	-	-	-	-	-	-	-	-
KOIEMPIK_02627	9.35e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02628	9.35e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02629	9.35e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02630	1.56e-22	-	-	-	-	-	-	-	-
KOIEMPIK_02631	3.26e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02632	6.58e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02633	0.0	inlJ	-	-	M	-	-	-	MucBP domain
KOIEMPIK_02634	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
KOIEMPIK_02635	1.27e-109	-	-	-	K	-	-	-	MarR family
KOIEMPIK_02636	9.28e-58	-	-	-	-	-	-	-	-
KOIEMPIK_02637	1.28e-51	-	-	-	-	-	-	-	-
KOIEMPIK_02638	2.54e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KOIEMPIK_02639	0.000204	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
KOIEMPIK_02641	2.3e-12	-	-	-	-	-	-	-	-
KOIEMPIK_02642	4.71e-47	-	-	-	-	-	-	-	-
KOIEMPIK_02643	2.13e-187	-	-	-	L	-	-	-	DNA replication protein
KOIEMPIK_02644	1.22e-280	-	-	-	S	-	-	-	Virulence-associated protein E
KOIEMPIK_02645	6.85e-113	-	-	-	-	-	-	-	-
KOIEMPIK_02646	6.46e-37	-	-	-	-	-	-	-	-
KOIEMPIK_02647	1.88e-70	-	-	-	S	-	-	-	Head-tail joining protein
KOIEMPIK_02648	3.14e-90	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
KOIEMPIK_02649	9.03e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
KOIEMPIK_02650	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
KOIEMPIK_02651	0.000349	-	-	-	-	-	-	-	-
KOIEMPIK_02652	9.13e-262	-	-	-	S	-	-	-	Phage portal protein
KOIEMPIK_02653	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
KOIEMPIK_02654	1.14e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KOIEMPIK_02655	4.65e-70	-	-	-	-	-	-	-	-
KOIEMPIK_02656	1.7e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF4065)
KOIEMPIK_02659	1.98e-40	-	-	-	-	-	-	-	-
KOIEMPIK_02661	1.89e-278	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KOIEMPIK_02662	8.09e-141	-	-	-	K	-	-	-	SIR2-like domain
KOIEMPIK_02667	1.57e-50	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
KOIEMPIK_02669	1.47e-22	-	-	-	K	ko:K22299	-	ko00000,ko03000	sequence-specific DNA binding
KOIEMPIK_02670	1.33e-06	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KOIEMPIK_02674	1.55e-12	-	-	-	S	-	-	-	Hypothetical protein (DUF2513)
KOIEMPIK_02675	1.19e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
KOIEMPIK_02676	5.24e-08	-	-	-	K	-	-	-	Transcriptional regulator, XRE family
KOIEMPIK_02679	6.59e-72	-	-	-	-	-	-	-	-
KOIEMPIK_02680	1.3e-111	-	-	-	-	-	-	-	-
KOIEMPIK_02682	8.32e-24	-	-	-	-	-	-	-	-
KOIEMPIK_02684	1.56e-94	-	-	-	-	-	-	-	-
KOIEMPIK_02685	2.09e-189	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
KOIEMPIK_02686	6.58e-174	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
KOIEMPIK_02687	2.18e-38	-	-	-	L	-	-	-	DnaD domain protein
KOIEMPIK_02688	2.49e-193	-	-	-	S	-	-	-	IstB-like ATP binding protein
KOIEMPIK_02690	5.23e-77	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
KOIEMPIK_02691	5.51e-82	-	-	-	-	-	-	-	-
KOIEMPIK_02692	3.3e-86	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KOIEMPIK_02693	4.26e-07	-	-	-	-	-	-	-	-
KOIEMPIK_02694	1.24e-105	-	-	-	S	-	-	-	Phage transcriptional regulator, ArpU family
KOIEMPIK_02697	1.96e-99	-	-	-	-	-	-	-	-
KOIEMPIK_02698	1.31e-11	-	-	-	-	-	-	-	-
KOIEMPIK_02699	1.38e-25	-	-	-	-	-	-	-	-
KOIEMPIK_02700	3e-39	-	-	-	-	-	-	-	-
KOIEMPIK_02702	7.99e-29	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
KOIEMPIK_02703	9.61e-85	-	-	-	S	-	-	-	Terminase small subunit
KOIEMPIK_02704	5.13e-167	-	-	-	S	-	-	-	Terminase-like family
KOIEMPIK_02705	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
KOIEMPIK_02706	2.82e-165	-	-	-	S	-	-	-	Phage Mu protein F like protein
KOIEMPIK_02707	8.28e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
KOIEMPIK_02708	1.35e-57	-	-	-	-	-	-	-	-
KOIEMPIK_02709	7.32e-221	-	-	-	S	-	-	-	Phage major capsid protein E
KOIEMPIK_02710	5.75e-67	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
KOIEMPIK_02711	2.78e-51	-	-	-	-	-	-	-	-
KOIEMPIK_02712	2.66e-82	-	-	-	-	-	-	-	-
KOIEMPIK_02713	2.39e-61	-	-	-	-	-	-	-	-
KOIEMPIK_02714	3.54e-125	-	-	-	-	-	-	-	-
KOIEMPIK_02715	5.4e-92	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
KOIEMPIK_02717	2e-311	-	-	-	D	-	-	-	domain protein
KOIEMPIK_02719	4.16e-176	-	-	-	S	-	-	-	Phage tail protein
KOIEMPIK_02720	1.05e-215	-	-	-	M	-	-	-	Prophage endopeptidase tail
KOIEMPIK_02723	5.92e-104	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KOIEMPIK_02725	4.78e-222	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
KOIEMPIK_02726	7.86e-65	-	-	-	-	-	-	-	-
KOIEMPIK_02727	3.72e-58	-	-	-	S	-	-	-	Bacteriophage holin
KOIEMPIK_02729	1.59e-79	-	-	-	K	-	-	-	IrrE N-terminal-like domain
KOIEMPIK_02731	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
KOIEMPIK_02732	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
KOIEMPIK_02733	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02734	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
KOIEMPIK_02735	5.54e-180	-	-	-	-	-	-	-	-
KOIEMPIK_02736	1.33e-77	-	-	-	-	-	-	-	-
KOIEMPIK_02737	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
KOIEMPIK_02738	2.1e-41	-	-	-	-	-	-	-	-
KOIEMPIK_02739	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
KOIEMPIK_02740	2.36e-248	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
KOIEMPIK_02741	2.5e-173	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
KOIEMPIK_02742	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
KOIEMPIK_02743	1.54e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
KOIEMPIK_02744	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KOIEMPIK_02745	1.99e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KOIEMPIK_02746	1.79e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KOIEMPIK_02747	1.24e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KOIEMPIK_02748	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KOIEMPIK_02749	1.44e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
KOIEMPIK_02750	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
KOIEMPIK_02751	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOIEMPIK_02752	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KOIEMPIK_02753	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOIEMPIK_02754	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KOIEMPIK_02755	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KOIEMPIK_02756	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KOIEMPIK_02757	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
KOIEMPIK_02758	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOIEMPIK_02759	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
KOIEMPIK_02760	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
KOIEMPIK_02761	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
KOIEMPIK_02762	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
KOIEMPIK_02763	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
KOIEMPIK_02764	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
KOIEMPIK_02765	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOIEMPIK_02766	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
KOIEMPIK_02767	1.23e-190	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
KOIEMPIK_02768	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
KOIEMPIK_02769	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
KOIEMPIK_02770	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
KOIEMPIK_02771	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
KOIEMPIK_02772	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
KOIEMPIK_02773	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
KOIEMPIK_02774	8.1e-261	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
KOIEMPIK_02775	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
KOIEMPIK_02776	1.34e-52	-	-	-	-	-	-	-	-
KOIEMPIK_02777	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
KOIEMPIK_02778	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
KOIEMPIK_02779	1.31e-119	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
KOIEMPIK_02780	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
KOIEMPIK_02781	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
KOIEMPIK_02782	5.82e-139	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
KOIEMPIK_02783	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
KOIEMPIK_02784	7.24e-291	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
KOIEMPIK_02785	2.63e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
KOIEMPIK_02786	6.4e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
KOIEMPIK_02787	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
KOIEMPIK_02788	1.15e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
KOIEMPIK_02789	4.35e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KOIEMPIK_02790	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
KOIEMPIK_02791	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KOIEMPIK_02792	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KOIEMPIK_02793	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KOIEMPIK_02794	3.3e-301	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
KOIEMPIK_02795	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KOIEMPIK_02796	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KOIEMPIK_02797	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
KOIEMPIK_02798	4.7e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
KOIEMPIK_02799	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
KOIEMPIK_02800	6.23e-183	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
KOIEMPIK_02801	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
KOIEMPIK_02802	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KOIEMPIK_02803	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
KOIEMPIK_02804	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KOIEMPIK_02805	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02806	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
KOIEMPIK_02807	0.0	-	-	-	L	ko:K07487	-	ko00000	Transposase
KOIEMPIK_02808	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
KOIEMPIK_02809	8.72e-297	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
KOIEMPIK_02810	3.84e-316	ymfH	-	-	S	-	-	-	Peptidase M16
KOIEMPIK_02811	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
KOIEMPIK_02812	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOIEMPIK_02813	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
KOIEMPIK_02814	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KOIEMPIK_02815	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
KOIEMPIK_02816	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
KOIEMPIK_02817	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KOIEMPIK_02818	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KOIEMPIK_02819	1.35e-93	-	-	-	-	-	-	-	-
KOIEMPIK_02820	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
KOIEMPIK_02821	2.07e-116	-	-	-	-	-	-	-	-
KOIEMPIK_02822	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KOIEMPIK_02823	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KOIEMPIK_02824	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KOIEMPIK_02825	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KOIEMPIK_02826	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
KOIEMPIK_02827	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOIEMPIK_02828	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
KOIEMPIK_02829	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KOIEMPIK_02830	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KOIEMPIK_02831	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
KOIEMPIK_02832	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KOIEMPIK_02833	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
KOIEMPIK_02834	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KOIEMPIK_02835	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KOIEMPIK_02836	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
KOIEMPIK_02837	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
KOIEMPIK_02838	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
KOIEMPIK_02839	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KOIEMPIK_02840	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
KOIEMPIK_02841	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
KOIEMPIK_02842	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KOIEMPIK_02843	2.74e-288	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KOIEMPIK_02844	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
KOIEMPIK_02845	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KOIEMPIK_02846	1.6e-96	-	-	-	-	-	-	-	-
KOIEMPIK_02847	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
KOIEMPIK_02848	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
KOIEMPIK_02849	4.47e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
KOIEMPIK_02850	5.32e-209	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
KOIEMPIK_02851	8.49e-66	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
KOIEMPIK_02852	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
KOIEMPIK_02853	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOIEMPIK_02854	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
KOIEMPIK_02855	2.52e-241	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
KOIEMPIK_02856	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
KOIEMPIK_02857	1.5e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
KOIEMPIK_02858	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
KOIEMPIK_02859	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
KOIEMPIK_02861	3.84e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
KOIEMPIK_02862	4.7e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOIEMPIK_02863	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
KOIEMPIK_02864	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
KOIEMPIK_02865	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
KOIEMPIK_02866	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
KOIEMPIK_02867	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KOIEMPIK_02868	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
KOIEMPIK_02869	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
KOIEMPIK_02870	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOIEMPIK_02871	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
KOIEMPIK_02872	5.28e-83	-	-	-	-	-	-	-	-
KOIEMPIK_02873	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
KOIEMPIK_02895	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
KOIEMPIK_02896	2.81e-178	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
KOIEMPIK_02897	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KOIEMPIK_02898	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KOIEMPIK_02899	2.62e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
KOIEMPIK_02900	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
KOIEMPIK_02901	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
KOIEMPIK_02902	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
KOIEMPIK_02903	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOIEMPIK_02904	1.27e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
KOIEMPIK_02905	2.51e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
KOIEMPIK_02906	5.57e-247	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
KOIEMPIK_02907	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
KOIEMPIK_02908	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
KOIEMPIK_02909	3.97e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOIEMPIK_02910	6.46e-207	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
KOIEMPIK_02912	2.17e-302	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
KOIEMPIK_02913	3.55e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
KOIEMPIK_02914	4.97e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KOIEMPIK_02915	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
KOIEMPIK_02916	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
KOIEMPIK_02917	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
KOIEMPIK_02918	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
KOIEMPIK_02919	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KOIEMPIK_02920	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
KOIEMPIK_02921	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
KOIEMPIK_02922	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KOIEMPIK_02923	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KOIEMPIK_02924	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KOIEMPIK_02925	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KOIEMPIK_02926	3.55e-312	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KOIEMPIK_02927	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KOIEMPIK_02928	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KOIEMPIK_02929	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
KOIEMPIK_02930	1.19e-186	ylmH	-	-	S	-	-	-	S4 domain protein
KOIEMPIK_02931	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
KOIEMPIK_02932	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KOIEMPIK_02933	5.47e-95	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
KOIEMPIK_02934	7.33e-101	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
KOIEMPIK_02935	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
KOIEMPIK_02936	2.05e-20	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
KOIEMPIK_02937	3.46e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KOIEMPIK_02938	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
KOIEMPIK_02939	7.74e-47	-	-	-	-	-	-	-	-
KOIEMPIK_02940	1.68e-157	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KOIEMPIK_02941	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
KOIEMPIK_02942	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
KOIEMPIK_02943	3.19e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KOIEMPIK_02944	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
KOIEMPIK_02945	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
KOIEMPIK_02946	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
KOIEMPIK_02947	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
KOIEMPIK_02948	0.0	-	-	-	N	-	-	-	domain, Protein
KOIEMPIK_02949	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
KOIEMPIK_02950	1.02e-155	-	-	-	S	-	-	-	repeat protein
KOIEMPIK_02951	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KOIEMPIK_02952	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOIEMPIK_02953	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
KOIEMPIK_02954	2.16e-39	-	-	-	-	-	-	-	-
KOIEMPIK_02955	5.96e-241	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
KOIEMPIK_02956	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOIEMPIK_02957	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
KOIEMPIK_02958	6.45e-111	-	-	-	-	-	-	-	-
KOIEMPIK_02959	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOIEMPIK_02960	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
KOIEMPIK_02961	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
KOIEMPIK_02962	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KOIEMPIK_02963	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
KOIEMPIK_02964	1.02e-207	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
KOIEMPIK_02965	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
KOIEMPIK_02966	4.1e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
KOIEMPIK_02967	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
KOIEMPIK_02968	7.38e-256	-	-	-	-	-	-	-	-
KOIEMPIK_02969	1.07e-37	-	-	-	-	-	-	-	-
KOIEMPIK_02970	2.12e-80	-	-	-	-	-	-	-	-
KOIEMPIK_02971	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
KOIEMPIK_02972	0.0	-	-	-	-	-	-	-	-
KOIEMPIK_02973	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
KOIEMPIK_02974	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KOIEMPIK_02975	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
KOIEMPIK_02976	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
KOIEMPIK_02977	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KOIEMPIK_02978	3.01e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
KOIEMPIK_02979	1.27e-162	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
KOIEMPIK_02980	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
KOIEMPIK_02981	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
KOIEMPIK_02982	2.07e-240	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
KOIEMPIK_02983	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
KOIEMPIK_02984	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KOIEMPIK_02985	2.22e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
KOIEMPIK_02986	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOIEMPIK_02987	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOIEMPIK_02988	9.34e-201	-	-	-	S	-	-	-	Tetratricopeptide repeat
KOIEMPIK_02989	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KOIEMPIK_02990	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KOIEMPIK_02991	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KOIEMPIK_02992	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
KOIEMPIK_02993	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
KOIEMPIK_02994	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
KOIEMPIK_02995	5.12e-31	-	-	-	-	-	-	-	-
KOIEMPIK_02996	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
KOIEMPIK_02997	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
KOIEMPIK_02998	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KOIEMPIK_02999	8.82e-164	epsB	-	-	M	-	-	-	biosynthesis protein
KOIEMPIK_03000	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
KOIEMPIK_03001	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
KOIEMPIK_03002	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
KOIEMPIK_03003	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
KOIEMPIK_03004	2.65e-248	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
KOIEMPIK_03005	4.8e-229	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
KOIEMPIK_03006	2.9e-292	-	-	-	-	-	-	-	-
KOIEMPIK_03007	1.61e-226	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
KOIEMPIK_03008	0.0	cps4J	-	-	S	-	-	-	MatE
KOIEMPIK_03009	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
KOIEMPIK_03010	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
KOIEMPIK_03011	7.34e-219	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KOIEMPIK_03012	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
KOIEMPIK_03013	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KOIEMPIK_03014	6.62e-62	-	-	-	-	-	-	-	-
KOIEMPIK_03015	2.05e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KOIEMPIK_03016	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
KOIEMPIK_03017	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
KOIEMPIK_03018	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
KOIEMPIK_03019	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KOIEMPIK_03020	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
KOIEMPIK_03021	5.79e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
KOIEMPIK_03022	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
KOIEMPIK_03023	4.15e-183	-	-	-	Q	-	-	-	Methyltransferase
KOIEMPIK_03024	1.75e-43	-	-	-	-	-	-	-	-
KOIEMPIK_03025	9.66e-74	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
KOIEMPIK_03032	3.05e-107	-	-	-	K	-	-	-	Peptidase S24-like
KOIEMPIK_03033	1.67e-16	-	-	-	-	-	-	-	-
KOIEMPIK_03034	3.89e-82	-	-	-	S	-	-	-	DNA binding
KOIEMPIK_03037	1.38e-07	-	-	-	-	-	-	-	-
KOIEMPIK_03043	1.53e-78	-	-	-	L	-	-	-	DnaD domain protein
KOIEMPIK_03044	1.69e-37	-	-	-	-	-	-	-	-
KOIEMPIK_03045	1.45e-54	-	-	-	-	-	-	-	-
KOIEMPIK_03046	1.63e-162	-	-	-	S	-	-	-	protein conserved in bacteria
KOIEMPIK_03047	1.35e-38	-	-	-	-	-	-	-	-
KOIEMPIK_03048	2.83e-58	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
KOIEMPIK_03049	4.66e-228	repA	-	-	S	-	-	-	Replication initiator protein A
KOIEMPIK_03050	3.57e-47	-	-	-	-	-	-	-	-
KOIEMPIK_03051	6.93e-194	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
KOIEMPIK_03052	1.65e-134	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KOIEMPIK_03054	5.69e-72	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
KOIEMPIK_03055	1.19e-177	-	-	-	L	-	-	-	Integrase core domain
KOIEMPIK_03056	1.9e-45	-	-	-	L	ko:K07483	-	ko00000	Transposase
KOIEMPIK_03057	0.0	cadA	-	-	P	-	-	-	P-type ATPase
KOIEMPIK_03058	6.96e-211	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
KOIEMPIK_03059	3.79e-26	-	-	-	-	-	-	-	-
KOIEMPIK_03060	2.14e-97	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KOIEMPIK_03061	2.47e-74	-	-	-	S	-	-	-	Arsenical resistance operon trans-acting repressor ArsD
KOIEMPIK_03062	3.29e-297	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KOIEMPIK_03063	0.0	arsA	3.6.3.16	-	D	ko:K01551	-	ko00000,ko01000,ko02000	Anion-transporting ATPase
KOIEMPIK_03064	1.57e-75	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	Helix-turn-helix domain
KOIEMPIK_03065	2.95e-72	-	-	-	L	-	-	-	Domain of unknown function (DUF4158)
KOIEMPIK_03066	4.23e-190	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KOIEMPIK_03067	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
KOIEMPIK_03068	8.36e-90	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
KOIEMPIK_03069	3.81e-66	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KOIEMPIK_03070	4.68e-71	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
KOIEMPIK_03074	3.64e-33	-	-	-	-	-	-	-	-
KOIEMPIK_03075	3.23e-104	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
KOIEMPIK_03076	8.43e-129	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
KOIEMPIK_03077	1.11e-45	-	-	-	-	-	-	-	-
KOIEMPIK_03078	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KOIEMPIK_03079	1.11e-239	-	-	-	L	-	-	-	MobA MobL family protein
KOIEMPIK_03080	8.87e-90	-	-	-	L	-	-	-	MobA MobL family protein
KOIEMPIK_03081	0.000378	mdt(A)	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector