ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
IEKKCDLC_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IEKKCDLC_00002 8.12e-262 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IEKKCDLC_00003 3.19e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
IEKKCDLC_00004 1.3e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IEKKCDLC_00005 6.18e-52 yaaB - - S - - - Domain of unknown function (DUF370)
IEKKCDLC_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEKKCDLC_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEKKCDLC_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00011 8.24e-234 yaaC - - S - - - YaaC-like Protein
IEKKCDLC_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IEKKCDLC_00013 0.0 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IEKKCDLC_00014 1.29e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IEKKCDLC_00015 2.86e-139 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IEKKCDLC_00016 1.59e-285 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IEKKCDLC_00017 8.42e-261 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
IEKKCDLC_00019 7.51e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
IEKKCDLC_00020 4.04e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
IEKKCDLC_00021 5.01e-278 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
IEKKCDLC_00022 5.85e-128 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
IEKKCDLC_00023 2.89e-110 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IEKKCDLC_00024 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEKKCDLC_00025 2.41e-52 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IEKKCDLC_00026 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEKKCDLC_00027 5.4e-43 yaaL - - S - - - Protein of unknown function (DUF2508)
IEKKCDLC_00028 6.44e-50 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
IEKKCDLC_00029 9.3e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00032 4.46e-42 csfB - - S - - - Inhibitor of sigma-G Gin
IEKKCDLC_00033 9.8e-135 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IEKKCDLC_00034 7.58e-248 yaaN - - P - - - Belongs to the TelA family
IEKKCDLC_00035 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
IEKKCDLC_00036 7.75e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IEKKCDLC_00037 5.03e-73 yaaQ - - S - - - protein conserved in bacteria
IEKKCDLC_00038 2.98e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
IEKKCDLC_00039 6.53e-230 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
IEKKCDLC_00040 9e-189 yaaT - - S - - - stage 0 sporulation protein
IEKKCDLC_00041 3.08e-56 yabA - - L - - - Involved in initiation control of chromosome replication
IEKKCDLC_00042 3.99e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
IEKKCDLC_00043 6.96e-64 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
IEKKCDLC_00044 1.41e-210 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IEKKCDLC_00045 6.14e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
IEKKCDLC_00046 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEKKCDLC_00047 5.03e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
IEKKCDLC_00048 5.02e-310 yabE - - T - - - protein conserved in bacteria
IEKKCDLC_00049 7.62e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IEKKCDLC_00050 8.41e-203 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IEKKCDLC_00051 1.41e-209 yabG - - S ko:K06436 - ko00000 peptidase
IEKKCDLC_00052 5.32e-53 veg - - S - - - protein conserved in bacteria
IEKKCDLC_00053 7.31e-38 sspF - - S ko:K06423 - ko00000 DNA topological change
IEKKCDLC_00054 7.83e-206 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IEKKCDLC_00055 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
IEKKCDLC_00056 7.5e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
IEKKCDLC_00057 4.23e-64 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IEKKCDLC_00058 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IEKKCDLC_00059 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEKKCDLC_00060 6.18e-137 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IEKKCDLC_00061 1.74e-136 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IEKKCDLC_00062 1.1e-54 yabK - - S - - - Peptide ABC transporter permease
IEKKCDLC_00063 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEKKCDLC_00064 8.02e-119 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
IEKKCDLC_00065 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEKKCDLC_00066 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IEKKCDLC_00067 8.51e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IEKKCDLC_00068 5.47e-66 yabP - - S - - - Sporulation protein YabP
IEKKCDLC_00069 1.18e-134 yabQ - - S - - - spore cortex biosynthesis protein
IEKKCDLC_00070 1.2e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
IEKKCDLC_00071 3.54e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IEKKCDLC_00074 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
IEKKCDLC_00075 3.79e-166 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IEKKCDLC_00076 1.91e-235 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
IEKKCDLC_00077 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IEKKCDLC_00078 1.05e-119 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
IEKKCDLC_00079 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEKKCDLC_00080 8.14e-178 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IEKKCDLC_00081 3.19e-206 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IEKKCDLC_00082 3.55e-201 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
IEKKCDLC_00083 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IEKKCDLC_00084 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IEKKCDLC_00085 5.35e-139 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
IEKKCDLC_00086 1.71e-207 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
IEKKCDLC_00087 2.24e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IEKKCDLC_00088 1.13e-81 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IEKKCDLC_00089 8.2e-118 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IEKKCDLC_00090 6.1e-40 yazB - - K - - - transcriptional
IEKKCDLC_00091 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEKKCDLC_00092 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
IEKKCDLC_00093 1.95e-54 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00103 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00104 2.14e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
IEKKCDLC_00105 6.61e-83 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
IEKKCDLC_00106 1.63e-258 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IEKKCDLC_00107 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
IEKKCDLC_00108 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEKKCDLC_00109 3.12e-250 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IEKKCDLC_00110 8.6e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
IEKKCDLC_00111 1.23e-160 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IEKKCDLC_00112 3.02e-111 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IEKKCDLC_00113 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEKKCDLC_00114 3.16e-151 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
IEKKCDLC_00115 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
IEKKCDLC_00116 4.11e-95 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IEKKCDLC_00117 2.04e-172 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEKKCDLC_00118 4.03e-115 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
IEKKCDLC_00119 1.39e-150 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
IEKKCDLC_00120 3.77e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IEKKCDLC_00121 1.28e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IEKKCDLC_00122 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IEKKCDLC_00123 8.66e-161 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IEKKCDLC_00124 2.33e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IEKKCDLC_00125 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IEKKCDLC_00126 7.25e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
IEKKCDLC_00127 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEKKCDLC_00128 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEKKCDLC_00129 5.94e-46 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
IEKKCDLC_00130 9.47e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEKKCDLC_00131 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IEKKCDLC_00132 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEKKCDLC_00133 2.35e-286 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEKKCDLC_00134 8.14e-240 ybaC - - S - - - Alpha/beta hydrolase family
IEKKCDLC_00135 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
IEKKCDLC_00136 1.77e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEKKCDLC_00137 3.68e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
IEKKCDLC_00138 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IEKKCDLC_00139 9.5e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IEKKCDLC_00140 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IEKKCDLC_00141 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IEKKCDLC_00142 1.69e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IEKKCDLC_00143 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IEKKCDLC_00144 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
IEKKCDLC_00145 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IEKKCDLC_00146 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IEKKCDLC_00147 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IEKKCDLC_00148 5.43e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IEKKCDLC_00149 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEKKCDLC_00150 1.08e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IEKKCDLC_00151 3.14e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IEKKCDLC_00152 8.29e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IEKKCDLC_00153 4.54e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IEKKCDLC_00154 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
IEKKCDLC_00155 5.15e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IEKKCDLC_00156 7.75e-296 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IEKKCDLC_00157 4.34e-158 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IEKKCDLC_00158 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IEKKCDLC_00159 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IEKKCDLC_00160 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
IEKKCDLC_00161 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IEKKCDLC_00162 2.28e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IEKKCDLC_00163 4.94e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEKKCDLC_00164 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
IEKKCDLC_00165 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEKKCDLC_00166 4.91e-190 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEKKCDLC_00167 1.13e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEKKCDLC_00168 8.74e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IEKKCDLC_00169 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEKKCDLC_00170 1.49e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
IEKKCDLC_00171 4.15e-184 ybaJ - - Q - - - Methyltransferase domain
IEKKCDLC_00172 4.47e-108 yizA - - S - - - Damage-inducible protein DinB
IEKKCDLC_00173 1.31e-102 ybaK - - S - - - Protein of unknown function (DUF2521)
IEKKCDLC_00174 1.98e-173 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IEKKCDLC_00175 2.12e-252 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IEKKCDLC_00176 6.81e-103 gerD - - - ko:K06294 - ko00000 -
IEKKCDLC_00177 1.25e-134 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
IEKKCDLC_00178 9.06e-183 pdaB - - G - - - Polysaccharide deacetylase
IEKKCDLC_00179 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00186 2.45e-271 glcP1 - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
IEKKCDLC_00187 3.65e-313 gabT 2.6.1.19 - E ko:K00823 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEKKCDLC_00188 1.1e-230 suhB 3.1.3.25, 3.1.3.7 - G ko:K01082,ko:K01092 ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070 ko00000,ko00001,ko00002,ko01000,ko03016 inositol monophosphate 1-phosphatase activity
IEKKCDLC_00189 9.77e-257 - 1.1.1.14, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00008 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IEKKCDLC_00190 9.57e-289 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IEKKCDLC_00191 1.54e-222 ybaS - - S - - - Na -dependent transporter
IEKKCDLC_00192 1.26e-148 ybbA - - S ko:K07017 - ko00000 Putative esterase
IEKKCDLC_00193 5.83e-229 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_00194 3.63e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_00195 2.1e-220 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
IEKKCDLC_00196 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
IEKKCDLC_00197 2.24e-300 ybbC - - S - - - protein conserved in bacteria
IEKKCDLC_00198 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
IEKKCDLC_00199 3.39e-313 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
IEKKCDLC_00200 1.75e-311 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_00201 3.44e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IEKKCDLC_00202 3.68e-112 ybbJ - - J - - - acetyltransferase
IEKKCDLC_00203 1.85e-99 ybbK - - S - - - Protein of unknown function (DUF523)
IEKKCDLC_00209 4.59e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IEKKCDLC_00210 1.11e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IEKKCDLC_00211 9e-188 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEKKCDLC_00212 8.36e-290 ybbR - - S - - - protein conserved in bacteria
IEKKCDLC_00213 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEKKCDLC_00214 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IEKKCDLC_00215 2.05e-197 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
IEKKCDLC_00216 2.02e-138 - - - S - - - ABC-2 family transporter protein
IEKKCDLC_00217 1.07e-124 ybdN - - - - - - -
IEKKCDLC_00218 2.61e-166 ybdO - - S - - - Domain of unknown function (DUF4885)
IEKKCDLC_00219 7.27e-207 dkgB - - S - - - Aldo/keto reductase family
IEKKCDLC_00220 3.49e-134 yxaC - - M - - - effector of murein hydrolase
IEKKCDLC_00221 1.41e-67 - - - S ko:K06518 - ko00000,ko02000 LrgA family
IEKKCDLC_00222 9.32e-92 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_00223 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IEKKCDLC_00224 7.81e-118 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
IEKKCDLC_00225 7.09e-132 - - - T - - - Histidine kinase
IEKKCDLC_00226 1.24e-104 - - - KT - - - helix_turn_helix, Lux Regulon
IEKKCDLC_00227 9.14e-172 yfiL - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_00228 6.11e-184 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IEKKCDLC_00229 2.18e-153 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IEKKCDLC_00230 1.62e-19 - - - - - - - -
IEKKCDLC_00231 1.97e-73 - - - Q - - - Thioesterase domain
IEKKCDLC_00232 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
IEKKCDLC_00233 0.0 - - - Q - - - Non-ribosomal peptide synthetase modules and related proteins
IEKKCDLC_00234 6.29e-149 - 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 PFAM Acyl transferase
IEKKCDLC_00235 0.0 - - - Q ko:K13614 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
IEKKCDLC_00236 0.0 - - - Q - - - Polyketide synthase modules and related proteins
IEKKCDLC_00237 7.24e-121 - - - Q - - - Flavin containing amine oxidoreductase
IEKKCDLC_00238 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
IEKKCDLC_00239 6.02e-51 - - - Q - - - Dimerisation domain
IEKKCDLC_00240 4.28e-102 - - - S - - - Domain of unknown function (DUF4879)
IEKKCDLC_00241 7.13e-52 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
IEKKCDLC_00242 1.3e-146 yqeB - - - - - - -
IEKKCDLC_00243 7.84e-55 ybyB - - - - - - -
IEKKCDLC_00244 0.0 ybeC - - E - - - amino acid
IEKKCDLC_00245 7.53e-54 - - - M - - - PFAM Glycosyl transferase family 2
IEKKCDLC_00246 9.16e-208 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
IEKKCDLC_00247 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
IEKKCDLC_00248 5.8e-23 - - - S - - - Protein of unknown function (DUF2651)
IEKKCDLC_00249 8.21e-267 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
IEKKCDLC_00251 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
IEKKCDLC_00252 2.44e-45 - - - - - - - -
IEKKCDLC_00253 1.69e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
IEKKCDLC_00254 3.53e-254 ypjH - - C ko:K08317 - ko00000,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IEKKCDLC_00255 5.6e-272 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IEKKCDLC_00256 1.56e-120 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEKKCDLC_00257 8.6e-113 ybfM - - S - - - SNARE associated Golgi protein
IEKKCDLC_00258 3.05e-194 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IEKKCDLC_00259 7.41e-56 ybfN - - - - - - -
IEKKCDLC_00260 5.76e-245 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
IEKKCDLC_00261 8.22e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEKKCDLC_00262 8.33e-255 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IEKKCDLC_00263 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IEKKCDLC_00264 2.92e-230 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
IEKKCDLC_00265 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IEKKCDLC_00266 1.11e-240 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IEKKCDLC_00267 8.86e-279 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_00268 2.36e-220 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
IEKKCDLC_00269 1.44e-44 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
IEKKCDLC_00270 5.89e-36 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
IEKKCDLC_00271 2.59e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEKKCDLC_00272 6.68e-143 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
IEKKCDLC_00273 8.74e-235 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IEKKCDLC_00274 3.82e-82 ydfP - - S ko:K15977 - ko00000 DoxX
IEKKCDLC_00275 6.28e-73 ydfQ - - CO - - - Thioredoxin
IEKKCDLC_00276 1.63e-82 ycbP - - S - - - Protein of unknown function (DUF2512)
IEKKCDLC_00277 1.05e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
IEKKCDLC_00278 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
IEKKCDLC_00279 8.68e-36 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IEKKCDLC_00280 2.74e-157 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IEKKCDLC_00281 5.93e-155 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IEKKCDLC_00282 6.71e-264 ycbU - - E - - - Selenocysteine lyase
IEKKCDLC_00283 1.61e-309 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
IEKKCDLC_00284 2.19e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IEKKCDLC_00285 2.05e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IEKKCDLC_00286 5.23e-144 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
IEKKCDLC_00287 1.68e-252 yccF - - K ko:K07039 - ko00000 SEC-C motif
IEKKCDLC_00288 1.08e-218 yccK - - C - - - Aldo keto reductase
IEKKCDLC_00289 1.38e-227 ycdA - - S - - - Domain of unknown function (DUF5105)
IEKKCDLC_00290 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IEKKCDLC_00291 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IEKKCDLC_00292 8.88e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IEKKCDLC_00293 2.86e-248 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
IEKKCDLC_00294 4.28e-179 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
IEKKCDLC_00295 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IEKKCDLC_00296 1.22e-212 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
IEKKCDLC_00297 1.4e-170 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IEKKCDLC_00298 1.19e-174 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IEKKCDLC_00299 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEKKCDLC_00300 1.16e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
IEKKCDLC_00301 3.63e-136 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IEKKCDLC_00302 2.46e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
IEKKCDLC_00303 2.12e-178 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
IEKKCDLC_00304 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
IEKKCDLC_00305 1.17e-246 yceH - - P - - - Belongs to the TelA family
IEKKCDLC_00306 5.22e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
IEKKCDLC_00307 1.28e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
IEKKCDLC_00308 2.45e-185 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IEKKCDLC_00309 7e-211 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
IEKKCDLC_00310 2.77e-271 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
IEKKCDLC_00311 3.27e-293 ycgA - - S - - - Membrane
IEKKCDLC_00312 4.41e-106 ycgB - - - - - - -
IEKKCDLC_00313 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
IEKKCDLC_00314 3.27e-228 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
IEKKCDLC_00315 0.0 mdr - - EGP - - - the major facilitator superfamily
IEKKCDLC_00316 6.92e-101 ycgE - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_00317 1.11e-147 ycgF - - E - - - Lysine exporter protein LysE YggA
IEKKCDLC_00318 6.95e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
IEKKCDLC_00319 9.42e-314 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IEKKCDLC_00320 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
IEKKCDLC_00321 1.29e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IEKKCDLC_00322 6.96e-07 - - - S - - - Bacillus cereus group antimicrobial protein
IEKKCDLC_00323 3.2e-139 tmrB - - S - - - AAA domain
IEKKCDLC_00324 7.76e-188 - 4.2.1.118 - G ko:K15652 ko00400,ko01110,ko01130,map00400,map01110,map01130 ko00000,ko00001,ko01000 Xylose isomerase-like TIM barrel
IEKKCDLC_00325 6.75e-304 - - - G ko:K08191,ko:K08194 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_00326 8.64e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IEKKCDLC_00327 1.98e-234 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
IEKKCDLC_00328 7.18e-188 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
IEKKCDLC_00329 9.61e-217 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IEKKCDLC_00330 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IEKKCDLC_00331 1.81e-310 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEKKCDLC_00332 8.26e-290 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
IEKKCDLC_00333 1.85e-239 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
IEKKCDLC_00334 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IEKKCDLC_00335 5.95e-75 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
IEKKCDLC_00336 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IEKKCDLC_00337 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEKKCDLC_00338 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
IEKKCDLC_00339 8.52e-287 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IEKKCDLC_00340 7.05e-290 yciC - - S - - - GTPases (G3E family)
IEKKCDLC_00341 1.29e-283 fdh 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IEKKCDLC_00342 9.31e-97 yckC - - S - - - membrane
IEKKCDLC_00343 3.31e-68 - - - S - - - Protein of unknown function (DUF2680)
IEKKCDLC_00344 0.0 yckE 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IEKKCDLC_00345 6.79e-91 nin - - S - - - Competence protein J (ComJ)
IEKKCDLC_00346 1.88e-101 nucA - - M - - - Deoxyribonuclease NucA/NucB
IEKKCDLC_00347 1.54e-124 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
IEKKCDLC_00348 1.05e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
IEKKCDLC_00349 4.1e-84 hxlR - - K - - - transcriptional
IEKKCDLC_00350 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_00351 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_00352 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
IEKKCDLC_00353 3.56e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
IEKKCDLC_00354 1.91e-316 - - - E - - - Aminotransferase class I and II
IEKKCDLC_00355 1.3e-167 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
IEKKCDLC_00356 3.11e-144 yczE - - S ko:K07149 - ko00000 membrane
IEKKCDLC_00357 1.18e-170 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IEKKCDLC_00358 2.9e-152 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IEKKCDLC_00359 1.89e-185 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
IEKKCDLC_00360 3.45e-205 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
IEKKCDLC_00361 3.44e-130 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IEKKCDLC_00362 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IEKKCDLC_00363 2.83e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
IEKKCDLC_00364 3.51e-102 yclD - - - - - - -
IEKKCDLC_00365 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
IEKKCDLC_00366 0.0 yclG - - M - - - Pectate lyase superfamily protein
IEKKCDLC_00368 0.0 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IEKKCDLC_00369 5.93e-302 gerKC - - S ko:K06297 - ko00000 spore germination
IEKKCDLC_00370 7.92e-250 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
IEKKCDLC_00371 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEKKCDLC_00372 2.56e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEKKCDLC_00373 1.56e-183 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IEKKCDLC_00374 1.49e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IEKKCDLC_00375 9.29e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_00376 5.04e-279 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
IEKKCDLC_00377 0.0 yxeQ - - S - - - MmgE/PrpD family
IEKKCDLC_00378 1.23e-153 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
IEKKCDLC_00379 9.02e-312 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
IEKKCDLC_00380 9.08e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_00381 0.0 yclK - - T - - - COG0642 Signal transduction histidine kinase
IEKKCDLC_00382 1.2e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IEKKCDLC_00384 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IEKKCDLC_00385 7.78e-211 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_00386 1.64e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_00387 3.8e-174 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_00388 6.82e-224 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
IEKKCDLC_00389 2.63e-316 ycnB - - EGP - - - the major facilitator superfamily
IEKKCDLC_00390 1.05e-195 ycnC - - K - - - Transcriptional regulator
IEKKCDLC_00391 1.38e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Nitroreductase family
IEKKCDLC_00392 1.97e-59 ycnE - - S - - - Monooxygenase
IEKKCDLC_00393 1.37e-70 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IEKKCDLC_00394 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEKKCDLC_00395 1.53e-287 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEKKCDLC_00396 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEKKCDLC_00397 8.27e-191 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
IEKKCDLC_00398 2.4e-186 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_00399 2.05e-131 ycnI - - S - - - protein conserved in bacteria
IEKKCDLC_00400 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
IEKKCDLC_00401 4.26e-138 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IEKKCDLC_00402 9.6e-73 - - - - - - - -
IEKKCDLC_00403 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
IEKKCDLC_00404 4.11e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IEKKCDLC_00405 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
IEKKCDLC_00406 8.28e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
IEKKCDLC_00408 4.66e-178 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IEKKCDLC_00409 6.12e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
IEKKCDLC_00410 3.78e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
IEKKCDLC_00411 2.07e-193 ycsI - - S - - - Belongs to the D-glutamate cyclase family
IEKKCDLC_00412 1.98e-176 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
IEKKCDLC_00413 2e-239 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
IEKKCDLC_00414 2.81e-168 kipR - - K - - - Transcriptional regulator
IEKKCDLC_00415 9.09e-149 ycsK - - E - - - anatomical structure formation involved in morphogenesis
IEKKCDLC_00417 8.14e-73 yczJ - - S - - - biosynthesis
IEKKCDLC_00418 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
IEKKCDLC_00419 1.05e-220 ycsN - - S - - - Oxidoreductase
IEKKCDLC_00420 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
IEKKCDLC_00421 0.0 ydaB - - IQ - - - acyl-CoA ligase
IEKKCDLC_00422 1.05e-204 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_00423 1.31e-123 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
IEKKCDLC_00424 2.34e-148 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IEKKCDLC_00425 1.83e-101 ydaG - - S - - - general stress protein
IEKKCDLC_00426 4.39e-177 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IEKKCDLC_00427 5.59e-64 ydzA - - EGP - - - Domain of unknown function (DUF3817)
IEKKCDLC_00428 7.97e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IEKKCDLC_00429 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEKKCDLC_00430 1.19e-259 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
IEKKCDLC_00431 5.39e-189 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
IEKKCDLC_00432 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
IEKKCDLC_00433 6.45e-303 ydaM - - M - - - Glycosyl transferase family group 2
IEKKCDLC_00434 0.0 ydaN - - S - - - Bacterial cellulose synthase subunit
IEKKCDLC_00435 0.0 ydaO - - E - - - amino acid
IEKKCDLC_00436 6.61e-25 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IEKKCDLC_00437 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
IEKKCDLC_00438 1.21e-62 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IEKKCDLC_00439 2.17e-99 - - - - - - - -
IEKKCDLC_00441 1.31e-152 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IEKKCDLC_00442 2.61e-53 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IEKKCDLC_00446 1.53e-115 - - - - - - - -
IEKKCDLC_00447 1.59e-55 - - - - - - - -
IEKKCDLC_00448 2.14e-53 - - - - - - - -
IEKKCDLC_00449 3.77e-288 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
IEKKCDLC_00451 2.37e-30 ydaT - - - - - - -
IEKKCDLC_00452 1.53e-93 yvaD - - S - - - Family of unknown function (DUF5360)
IEKKCDLC_00453 1.66e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
IEKKCDLC_00454 1.8e-180 ydbA - - P - - - EcsC protein family
IEKKCDLC_00455 2.34e-10 gsiB - - S ko:K06884 - ko00000 general stress protein
IEKKCDLC_00456 9.34e-85 ydbB - - G - - - Cupin domain
IEKKCDLC_00457 2.48e-80 ydbC - - S - - - Domain of unknown function (DUF4937
IEKKCDLC_00458 1.64e-199 ydbD - - P ko:K07217 - ko00000 Catalase
IEKKCDLC_00459 1.56e-254 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IEKKCDLC_00460 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IEKKCDLC_00461 3.67e-153 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IEKKCDLC_00462 3.91e-287 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEKKCDLC_00463 1.43e-229 ydbI - - S - - - AI-2E family transporter
IEKKCDLC_00464 9.66e-221 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_00465 2.44e-167 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IEKKCDLC_00466 6.56e-70 ydbL - - - - - - -
IEKKCDLC_00467 2.62e-262 ydbM - - I - - - acyl-CoA dehydrogenase
IEKKCDLC_00468 1.13e-15 - - - S - - - Fur-regulated basic protein B
IEKKCDLC_00469 3.81e-13 - - - S - - - Fur-regulated basic protein A
IEKKCDLC_00470 9.92e-161 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEKKCDLC_00471 2.25e-74 ydbP - - CO - - - Thioredoxin
IEKKCDLC_00472 2.16e-258 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
IEKKCDLC_00473 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IEKKCDLC_00474 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IEKKCDLC_00475 6.83e-109 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
IEKKCDLC_00476 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
IEKKCDLC_00477 4.21e-138 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
IEKKCDLC_00478 9.65e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IEKKCDLC_00479 1.57e-235 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
IEKKCDLC_00480 1.39e-279 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEKKCDLC_00481 6.68e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IEKKCDLC_00482 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
IEKKCDLC_00483 4.1e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
IEKKCDLC_00484 1.09e-75 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
IEKKCDLC_00485 1.73e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IEKKCDLC_00486 8.83e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
IEKKCDLC_00487 2.8e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
IEKKCDLC_00488 7.1e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IEKKCDLC_00489 1.14e-180 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEKKCDLC_00490 5.75e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
IEKKCDLC_00491 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
IEKKCDLC_00492 1.78e-21 - - - - - - - -
IEKKCDLC_00493 1.22e-75 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
IEKKCDLC_00502 2.28e-05 - - - I - - - phosphoesterase, PA-phosphatase related
IEKKCDLC_00503 1e-09 - - - S - - - Doxx family
IEKKCDLC_00504 1.76e-101 - - - K - - - Transcriptional regulator
IEKKCDLC_00505 6.52e-125 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEKKCDLC_00506 3.9e-86 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IEKKCDLC_00507 1.26e-74 - - - LO - - - Belongs to the peptidase S16 family
IEKKCDLC_00508 0.0 - - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Transporter
IEKKCDLC_00509 1.61e-107 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
IEKKCDLC_00510 5.23e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
IEKKCDLC_00511 3.46e-84 - - - S - - - YjbR
IEKKCDLC_00512 5.6e-87 ywnA - - K - - - Transcriptional regulator
IEKKCDLC_00513 1.34e-145 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
IEKKCDLC_00514 3.87e-42 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
IEKKCDLC_00515 3.43e-101 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
IEKKCDLC_00516 1.53e-52 yrkD - - S - - - protein conserved in bacteria
IEKKCDLC_00517 5.61e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
IEKKCDLC_00518 1.42e-76 - - - P - - - Rhodanese Homology Domain
IEKKCDLC_00519 1.08e-121 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
IEKKCDLC_00520 2.27e-251 yrkH - - P - - - Rhodanese Homology Domain
IEKKCDLC_00521 6.46e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
IEKKCDLC_00522 1.25e-166 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
IEKKCDLC_00523 2.49e-157 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IEKKCDLC_00524 7.92e-129 - - - S - - - Protein of unknown function (DUF2812)
IEKKCDLC_00525 6.75e-67 - - - K - - - Transcriptional regulator PadR-like family
IEKKCDLC_00526 3.42e-232 - - - S - - - Patatin-like phospholipase
IEKKCDLC_00527 2.47e-101 - - - S - - - DinB superfamily
IEKKCDLC_00528 1.49e-84 - - - G - - - Cupin domain
IEKKCDLC_00530 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
IEKKCDLC_00531 3.87e-213 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
IEKKCDLC_00532 1.5e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
IEKKCDLC_00534 7.47e-128 yrkC - - G - - - Cupin domain
IEKKCDLC_00535 4.57e-111 ykkA - - S - - - Protein of unknown function (DUF664)
IEKKCDLC_00536 7.85e-187 dapA7 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Dihydrodipicolinate synthetase family
IEKKCDLC_00538 1.01e-254 cfr 2.1.1.224 - J ko:K15632 - ko00000,ko01000,ko01504,ko03009 Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
IEKKCDLC_00539 9.09e-75 ydeH - - - - - - -
IEKKCDLC_00540 5.27e-110 - - - F - - - nucleoside 2-deoxyribosyltransferase
IEKKCDLC_00541 6.53e-249 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEKKCDLC_00542 4.34e-189 - - - Q - - - ubiE/COQ5 methyltransferase family
IEKKCDLC_00543 3.03e-190 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7 - H ko:K00941,ko:K14153 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IEKKCDLC_00544 6.9e-298 - - - G - - - Haloacid dehalogenase-like hydrolase
IEKKCDLC_00545 4.17e-212 - - - S - - - Sodium Bile acid symporter family
IEKKCDLC_00546 5.46e-259 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
IEKKCDLC_00547 7.29e-87 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
IEKKCDLC_00548 7.9e-288 nhaC_1 - - C - - - antiporter
IEKKCDLC_00549 0.0 - - - K ko:K00375 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
IEKKCDLC_00550 1.03e-146 paiB - - K ko:K07734 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_00552 3.97e-246 ydeR - - EGP - - - Uncharacterised MFS-type transporter YbfB
IEKKCDLC_00553 4.89e-132 ydeS - - K - - - Transcriptional regulator
IEKKCDLC_00554 5.04e-200 ydeK - - EG - - - -transporter
IEKKCDLC_00555 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEKKCDLC_00556 2.84e-63 yraD - - M ko:K06439 - ko00000 Spore coat protein
IEKKCDLC_00557 9.81e-33 yraE - - - ko:K06440 - ko00000 -
IEKKCDLC_00558 3.41e-279 adhB 1.1.1.1, 1.1.1.284 - E ko:K00121 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IEKKCDLC_00559 4.76e-84 yraF - - M - - - Spore coat protein
IEKKCDLC_00560 1.41e-48 yraG - - - ko:K06440 - ko00000 -
IEKKCDLC_00561 8.51e-276 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_00562 1.39e-142 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEKKCDLC_00563 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
IEKKCDLC_00564 5.65e-170 puuD - - S ko:K07010 - ko00000,ko01002 Peptidase C26
IEKKCDLC_00566 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
IEKKCDLC_00567 6.42e-128 ynaD - - J - - - Acetyltransferase (GNAT) domain
IEKKCDLC_00568 1.6e-189 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IEKKCDLC_00569 6.59e-249 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 COG0371 Glycerol dehydrogenase and related enzymes
IEKKCDLC_00570 3.34e-269 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IEKKCDLC_00571 6.78e-289 fabF_1 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IEKKCDLC_00572 2.24e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
IEKKCDLC_00573 7.39e-157 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
IEKKCDLC_00574 1.46e-106 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
IEKKCDLC_00575 1.5e-15 bltR - - K - - - helix_turn_helix, mercury resistance
IEKKCDLC_00576 1.65e-147 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
IEKKCDLC_00577 1.63e-188 - - - Q - - - ubiE/COQ5 methyltransferase family
IEKKCDLC_00578 8.45e-212 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
IEKKCDLC_00579 1.88e-153 ydhC - - K - - - FCD
IEKKCDLC_00580 3.92e-290 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IEKKCDLC_00583 0.0 pbpE - - V - - - Beta-lactamase
IEKKCDLC_00585 2.49e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
IEKKCDLC_00586 1.58e-247 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
IEKKCDLC_00587 7.17e-172 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
IEKKCDLC_00588 3.25e-154 - - - K ko:K05799 - ko00000,ko03000 FCD
IEKKCDLC_00589 1.23e-276 yycB1 - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
IEKKCDLC_00590 1.48e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
IEKKCDLC_00591 4.48e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IEKKCDLC_00592 3.63e-136 yvdT_1 - - K - - - Transcriptional regulator
IEKKCDLC_00593 0.0 ybeC - - E - - - amino acid
IEKKCDLC_00594 5.15e-213 ydhU - - P ko:K07217 - ko00000 Catalase
IEKKCDLC_00595 2.7e-110 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
IEKKCDLC_00596 7.45e-233 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
IEKKCDLC_00597 0.0 iolT - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IEKKCDLC_00600 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00603 1.7e-234 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IEKKCDLC_00604 9.02e-113 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
IEKKCDLC_00605 3.41e-161 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
IEKKCDLC_00606 1.41e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IEKKCDLC_00607 7.58e-244 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IEKKCDLC_00608 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
IEKKCDLC_00609 2.95e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IEKKCDLC_00610 1.51e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IEKKCDLC_00611 1.72e-29 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IEKKCDLC_00612 2.73e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IEKKCDLC_00613 1.11e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
IEKKCDLC_00614 3.36e-164 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
IEKKCDLC_00615 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IEKKCDLC_00616 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IEKKCDLC_00617 7.07e-51 - - - S - - - Protein of unknown function (DUF4064)
IEKKCDLC_00618 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
IEKKCDLC_00619 2.91e-256 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
IEKKCDLC_00620 2.45e-315 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
IEKKCDLC_00621 1.73e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
IEKKCDLC_00622 3.45e-39 yjdJ - - S - - - Domain of unknown function (DUF4306)
IEKKCDLC_00623 1.17e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
IEKKCDLC_00624 5.18e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEKKCDLC_00625 1.35e-163 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
IEKKCDLC_00626 5.57e-224 ydjI - - S - - - virion core protein (lumpy skin disease virus)
IEKKCDLC_00627 0.0 oatA - - I - - - Acyltransferase family
IEKKCDLC_00628 7.99e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
IEKKCDLC_00629 1.87e-113 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IEKKCDLC_00630 1e-248 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
IEKKCDLC_00631 7.91e-83 ydjM - - M - - - Lytic transglycolase
IEKKCDLC_00632 1.23e-195 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
IEKKCDLC_00634 2.02e-47 ydjO - - S - - - Cold-inducible protein YdjO
IEKKCDLC_00635 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
IEKKCDLC_00636 4.33e-315 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IEKKCDLC_00637 1.68e-196 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEKKCDLC_00638 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
IEKKCDLC_00639 1.89e-275 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IEKKCDLC_00640 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
IEKKCDLC_00641 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
IEKKCDLC_00642 4.04e-166 - - - K - - - Acetyltransferase (GNAT) domain
IEKKCDLC_00643 1.15e-122 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IEKKCDLC_00644 1.29e-314 - - - S - - - Domain of unknown function (DUF4179)
IEKKCDLC_00645 1.23e-269 pbuG - - S ko:K06901 - ko00000,ko02000 permease
IEKKCDLC_00646 5.08e-167 yebC - - M - - - Membrane
IEKKCDLC_00648 1.48e-119 yebE - - S - - - UPF0316 protein
IEKKCDLC_00649 2.21e-38 yebG - - S - - - NETI protein
IEKKCDLC_00650 1.13e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IEKKCDLC_00651 1.31e-286 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IEKKCDLC_00652 6.38e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEKKCDLC_00653 7.13e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
IEKKCDLC_00654 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEKKCDLC_00655 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEKKCDLC_00656 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IEKKCDLC_00657 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IEKKCDLC_00658 5.33e-244 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
IEKKCDLC_00659 7.3e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IEKKCDLC_00660 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
IEKKCDLC_00661 3.43e-299 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
IEKKCDLC_00662 1.2e-33 - - - S - - - Protein of unknown function (DUF2892)
IEKKCDLC_00663 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
IEKKCDLC_00664 7.32e-248 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
IEKKCDLC_00665 2.03e-67 yerC - - S - - - protein conserved in bacteria
IEKKCDLC_00666 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
IEKKCDLC_00667 8.71e-164 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IEKKCDLC_00668 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
IEKKCDLC_00669 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IEKKCDLC_00670 2.74e-286 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
IEKKCDLC_00671 1.8e-248 yerI - - S - - - homoserine kinase type II (protein kinase fold)
IEKKCDLC_00672 1.68e-157 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IEKKCDLC_00673 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEKKCDLC_00674 1.81e-60 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEKKCDLC_00675 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IEKKCDLC_00676 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEKKCDLC_00677 3.85e-198 yerO - - K - - - Transcriptional regulator
IEKKCDLC_00678 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IEKKCDLC_00679 5.78e-215 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IEKKCDLC_00680 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEKKCDLC_00682 9.62e-203 cylA - - V ko:K01990,ko:K09695,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IEKKCDLC_00683 1.17e-26 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
IEKKCDLC_00684 4.21e-131 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
IEKKCDLC_00685 6.87e-35 - - - S - - - Protein of unknown function, DUF600
IEKKCDLC_00686 7.24e-102 - - - S - - - Protein of unknown function, DUF600
IEKKCDLC_00687 3.33e-73 - - - S - - - Protein of unknown function, DUF600
IEKKCDLC_00688 5.47e-70 - - - S - - - Protein of unknown function, DUF600
IEKKCDLC_00689 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
IEKKCDLC_00690 1.05e-24 - - - - - - - -
IEKKCDLC_00691 3.12e-162 yeeN - - K - - - transcriptional regulatory protein
IEKKCDLC_00693 4.61e-61 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
IEKKCDLC_00694 1.62e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
IEKKCDLC_00695 1.48e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
IEKKCDLC_00696 3.56e-126 yesJ - - K - - - Acetyltransferase (GNAT) family
IEKKCDLC_00697 5.92e-05 - - - - - - - -
IEKKCDLC_00698 3.01e-155 yetF - - S - - - membrane
IEKKCDLC_00699 6.42e-72 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
IEKKCDLC_00700 1.8e-83 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEKKCDLC_00701 4.42e-197 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEKKCDLC_00702 1.34e-31 - - - S - - - Uncharacterized small protein (DUF2292)
IEKKCDLC_00703 1.06e-72 - - - H - - - riboflavin kinase activity
IEKKCDLC_00704 2.19e-136 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
IEKKCDLC_00706 2.08e-117 yetL - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_00707 2.34e-262 yetM - - CH - - - FAD binding domain
IEKKCDLC_00708 1.38e-251 yetN - - S - - - Protein of unknown function (DUF3900)
IEKKCDLC_00709 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IEKKCDLC_00711 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IEKKCDLC_00712 1.02e-188 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
IEKKCDLC_00713 6.8e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
IEKKCDLC_00714 2.31e-230 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
IEKKCDLC_00715 3.59e-285 yfnE - - S - - - Glycosyltransferase like family 2
IEKKCDLC_00716 1.99e-238 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
IEKKCDLC_00717 2.7e-278 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_00718 8.39e-313 yfnA - - E ko:K03294 - ko00000 amino acid
IEKKCDLC_00719 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEKKCDLC_00720 2.85e-169 yfmS - - NT - - - chemotaxis protein
IEKKCDLC_00721 8.54e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IEKKCDLC_00722 3.45e-265 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
IEKKCDLC_00723 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IEKKCDLC_00724 8.7e-91 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
IEKKCDLC_00725 1.25e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
IEKKCDLC_00726 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IEKKCDLC_00727 1.53e-265 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
IEKKCDLC_00728 4.87e-85 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
IEKKCDLC_00729 4.91e-241 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
IEKKCDLC_00730 4.9e-76 yflT - - S - - - Heat induced stress protein YflT
IEKKCDLC_00731 1.03e-304 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IEKKCDLC_00732 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
IEKKCDLC_00737 7.54e-07 - - - S - - - domain, Protein
IEKKCDLC_00739 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IEKKCDLC_00740 2.39e-155 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
IEKKCDLC_00741 8.33e-228 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
IEKKCDLC_00742 5.77e-287 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IEKKCDLC_00743 5.69e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IEKKCDLC_00744 8.63e-279 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IEKKCDLC_00745 9.63e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
IEKKCDLC_00746 2.51e-158 yflK - - S - - - protein conserved in bacteria
IEKKCDLC_00747 5.84e-21 yflJ - - S - - - Protein of unknown function (DUF2639)
IEKKCDLC_00748 1.98e-26 yflI - - - - - - -
IEKKCDLC_00749 2.78e-65 yflH - - S - - - Protein of unknown function (DUF3243)
IEKKCDLC_00750 6.62e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
IEKKCDLC_00751 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IEKKCDLC_00752 6.75e-96 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
IEKKCDLC_00753 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
IEKKCDLC_00754 8.46e-84 ydhN1 - - S - - - Domain of unknown function (DUF1992)
IEKKCDLC_00755 1.43e-104 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IEKKCDLC_00756 8.17e-52 ydgA - - S - - - Spore germination protein gerPA/gerPF
IEKKCDLC_00757 7.28e-51 ydgB - - S - - - Spore germination protein gerPA/gerPF
IEKKCDLC_00758 7.43e-312 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_00759 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
IEKKCDLC_00760 9.69e-165 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
IEKKCDLC_00761 1.45e-158 frp - - C - - - nitroreductase
IEKKCDLC_00762 6e-167 yibF - - S - - - YibE/F-like protein
IEKKCDLC_00763 6.6e-257 yibE - - S - - - YibE/F-like protein
IEKKCDLC_00764 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IEKKCDLC_00765 1.58e-117 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IEKKCDLC_00766 2.15e-237 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
IEKKCDLC_00767 3.54e-209 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IEKKCDLC_00768 4.11e-174 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IEKKCDLC_00769 2e-251 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_00770 2.97e-41 yfkK - - S - - - Belongs to the UPF0435 family
IEKKCDLC_00771 2.8e-111 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEKKCDLC_00772 1.76e-68 yfkI - - S - - - gas vesicle protein
IEKKCDLC_00773 1.37e-185 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
IEKKCDLC_00774 6.71e-12 - - - - - - - -
IEKKCDLC_00775 1.45e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_00776 8.42e-239 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
IEKKCDLC_00777 5.66e-186 yfkD - - S - - - YfkD-like protein
IEKKCDLC_00778 5.2e-189 yfkC - - M - - - Mechanosensitive ion channel
IEKKCDLC_00779 2.4e-281 yfkA - - S - - - YfkB-like domain
IEKKCDLC_00780 7.99e-37 yfjT - - - - - - -
IEKKCDLC_00781 4.36e-199 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
IEKKCDLC_00782 6.85e-194 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IEKKCDLC_00784 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
IEKKCDLC_00785 1.72e-208 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IEKKCDLC_00786 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEKKCDLC_00789 2.97e-245 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEKKCDLC_00790 2.71e-116 yfjM - - S - - - Psort location Cytoplasmic, score
IEKKCDLC_00791 5.55e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IEKKCDLC_00792 1.52e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IEKKCDLC_00793 4.62e-273 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IEKKCDLC_00794 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IEKKCDLC_00795 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
IEKKCDLC_00796 6.64e-22 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
IEKKCDLC_00797 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IEKKCDLC_00798 1.56e-178 glvR - - F ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
IEKKCDLC_00799 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_00800 0.0 - - - M - - - Peptidase_G2, IMC autoproteolytic cleavage domain
IEKKCDLC_00801 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
IEKKCDLC_00802 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IEKKCDLC_00803 5.54e-82 yfiD3 - - S - - - DoxX
IEKKCDLC_00804 4.72e-205 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
IEKKCDLC_00805 2.08e-214 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IEKKCDLC_00806 5.62e-126 padR - - K - - - transcriptional
IEKKCDLC_00807 4.22e-143 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IEKKCDLC_00808 1.55e-235 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IEKKCDLC_00810 0.0 - 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IEKKCDLC_00811 2.87e-61 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IEKKCDLC_00812 6.62e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
IEKKCDLC_00813 0.0 yfiU - - EGP - - - the major facilitator superfamily
IEKKCDLC_00814 1.38e-108 yfiV - - K - - - transcriptional
IEKKCDLC_00815 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IEKKCDLC_00816 1.31e-211 yfhB - - S - - - PhzF family
IEKKCDLC_00817 4.76e-137 yfhC - - C - - - nitroreductase
IEKKCDLC_00818 3.61e-34 yfhD - - S - - - YfhD-like protein
IEKKCDLC_00820 1.72e-214 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
IEKKCDLC_00821 9e-183 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
IEKKCDLC_00822 1.12e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
IEKKCDLC_00823 8.19e-268 yfhI - - EGP - - - -transporter
IEKKCDLC_00825 2.86e-215 mpr - - M - - - Belongs to the peptidase S1B family
IEKKCDLC_00826 2.57e-59 yfhJ - - S - - - WVELL protein
IEKKCDLC_00827 9.84e-123 yfhK - - T - - - Bacterial SH3 domain homologues
IEKKCDLC_00828 1.48e-57 yfhL - - S - - - SdpI/YhfL protein family
IEKKCDLC_00829 9.66e-219 - - - S - - - Alpha/beta hydrolase family
IEKKCDLC_00830 1.35e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IEKKCDLC_00831 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
IEKKCDLC_00832 1.2e-235 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
IEKKCDLC_00833 9.18e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
IEKKCDLC_00834 2.54e-50 yfhS - - - - - - -
IEKKCDLC_00835 3.81e-173 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_00836 4.77e-06 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
IEKKCDLC_00837 1.4e-49 ygaB - - S - - - YgaB-like protein
IEKKCDLC_00838 2.32e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
IEKKCDLC_00839 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
IEKKCDLC_00840 5.48e-239 ygaE - - S - - - Membrane
IEKKCDLC_00841 6.86e-314 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IEKKCDLC_00842 1.39e-111 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
IEKKCDLC_00843 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
IEKKCDLC_00844 4.67e-75 ygzB - - S - - - UPF0295 protein
IEKKCDLC_00845 7.89e-213 ygxA - - S - - - Nucleotidyltransferase-like
IEKKCDLC_00846 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_00863 5.4e-120 - - - C - - - Na+/H+ antiporter family
IEKKCDLC_00864 5.76e-220 - - - C - - - Na+/H+ antiporter family
IEKKCDLC_00865 3.56e-169 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
IEKKCDLC_00866 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IEKKCDLC_00867 0.0 ygaK - - C - - - Berberine and berberine like
IEKKCDLC_00869 9e-291 oppA5 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 PFAM extracellular solute-binding protein family 5
IEKKCDLC_00870 4.08e-179 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IEKKCDLC_00871 6.2e-162 - - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEKKCDLC_00872 7.73e-170 oppD3 - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_00873 3.29e-168 oppF9 - - E ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_00874 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IEKKCDLC_00875 2.32e-234 - - - S ko:K07045 - ko00000 Amidohydrolase
IEKKCDLC_00876 4.5e-180 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IEKKCDLC_00877 7.12e-229 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
IEKKCDLC_00878 8.27e-186 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IEKKCDLC_00879 8.61e-273 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
IEKKCDLC_00880 5.64e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEKKCDLC_00881 5.25e-106 ygaO - - - - - - -
IEKKCDLC_00882 9.41e-32 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_00884 1.58e-146 yhzB - - S - - - B3/4 domain
IEKKCDLC_00885 2.42e-286 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IEKKCDLC_00886 2.13e-226 yhbB - - S - - - Putative amidase domain
IEKKCDLC_00887 2.8e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IEKKCDLC_00888 1.39e-140 yhbD - - K - - - Protein of unknown function (DUF4004)
IEKKCDLC_00889 2.44e-86 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IEKKCDLC_00890 6.68e-93 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
IEKKCDLC_00891 1.23e-07 - - - - - - - -
IEKKCDLC_00892 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
IEKKCDLC_00893 5.91e-279 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
IEKKCDLC_00894 1.19e-97 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
IEKKCDLC_00895 1.54e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
IEKKCDLC_00896 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
IEKKCDLC_00897 9.09e-129 wrbA 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
IEKKCDLC_00898 1.41e-72 yhcC - - - - - - -
IEKKCDLC_00899 2.33e-66 - - - - - - - -
IEKKCDLC_00900 4.71e-81 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_00901 1.46e-161 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_00902 1.93e-214 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_00903 1.29e-208 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IEKKCDLC_00904 7.28e-42 cspB - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
IEKKCDLC_00905 3.54e-191 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
IEKKCDLC_00906 6.79e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
IEKKCDLC_00907 1.29e-293 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEKKCDLC_00908 1.11e-79 yhcM - - - - - - -
IEKKCDLC_00909 2.69e-122 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IEKKCDLC_00910 3.2e-205 yhcP - - - - - - -
IEKKCDLC_00911 1.81e-150 yhcQ - - M - - - Spore coat protein
IEKKCDLC_00912 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IEKKCDLC_00913 4.55e-137 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
IEKKCDLC_00914 9.64e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IEKKCDLC_00915 1.88e-92 yhcU - - S - - - Family of unknown function (DUF5365)
IEKKCDLC_00916 6.12e-91 yhcV - - S - - - COG0517 FOG CBS domain
IEKKCDLC_00917 3.41e-161 yhcW - - S ko:K07025 - ko00000 hydrolase
IEKKCDLC_00918 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IEKKCDLC_00919 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEKKCDLC_00920 5.16e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IEKKCDLC_00921 9.46e-198 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
IEKKCDLC_00922 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IEKKCDLC_00923 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IEKKCDLC_00924 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
IEKKCDLC_00925 3.84e-28 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_00926 7.46e-141 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEKKCDLC_00927 1.19e-116 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
IEKKCDLC_00928 5.75e-52 yhdB - - S - - - YhdB-like protein
IEKKCDLC_00929 6.94e-70 yhdC - - S - - - Protein of unknown function (DUF3889)
IEKKCDLC_00930 2.56e-298 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IEKKCDLC_00931 1.32e-96 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
IEKKCDLC_00932 0.0 ygxB - - M - - - Conserved TM helix
IEKKCDLC_00933 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
IEKKCDLC_00934 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
IEKKCDLC_00935 2.62e-176 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IEKKCDLC_00936 7e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_00937 4.9e-263 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IEKKCDLC_00938 7.51e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_00939 8.9e-317 yhdG - - E ko:K03294 - ko00000 amino acid
IEKKCDLC_00940 1.78e-268 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IEKKCDLC_00941 8.62e-59 yhdK - - S - - - Sigma-M inhibitor protein
IEKKCDLC_00942 6.88e-257 yhdL - - S - - - Sigma factor regulator N-terminal
IEKKCDLC_00943 4.6e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IEKKCDLC_00944 3.75e-141 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IEKKCDLC_00945 3.94e-307 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IEKKCDLC_00946 1.19e-93 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
IEKKCDLC_00947 8.17e-286 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IEKKCDLC_00948 2.24e-300 - 2.3.1.179 - I ko:K00646,ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IEKKCDLC_00949 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
IEKKCDLC_00950 2.12e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEKKCDLC_00951 1.43e-78 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEKKCDLC_00952 1.28e-165 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IEKKCDLC_00953 1.45e-08 yhdX - - S - - - Uncharacterized protein YhdX
IEKKCDLC_00954 6.68e-262 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
IEKKCDLC_00955 5.67e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IEKKCDLC_00956 1.7e-201 nodB1 - - G - - - deacetylase
IEKKCDLC_00957 1.19e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IEKKCDLC_00958 1.22e-114 pksA - - K - - - Transcriptional regulator
IEKKCDLC_00959 6.57e-125 ymcC - - S - - - Membrane
IEKKCDLC_00960 2.91e-109 - - - T - - - universal stress protein
IEKKCDLC_00962 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IEKKCDLC_00963 0.0 yheH - - V ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
IEKKCDLC_00964 6.68e-143 yheG - - GM - - - NAD(P)H-binding
IEKKCDLC_00966 3.3e-39 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IEKKCDLC_00967 2.12e-49 yheE - - S - - - Family of unknown function (DUF5342)
IEKKCDLC_00968 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
IEKKCDLC_00969 9.28e-274 yheC - - HJ - - - YheC/D like ATP-grasp
IEKKCDLC_00970 2.73e-264 yheB - - S - - - Belongs to the UPF0754 family
IEKKCDLC_00971 2.32e-70 yheA - - S - - - Belongs to the UPF0342 family
IEKKCDLC_00972 5.83e-257 yhaZ - - L - - - DNA alkylation repair enzyme
IEKKCDLC_00973 1.03e-205 yhaX - - S - - - haloacid dehalogenase-like hydrolase
IEKKCDLC_00974 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
IEKKCDLC_00975 0.0 - 1.14.13.59 - Q ko:K03897 ko00310,ko01120,map00310,map01120 ko00000,ko00001,ko01000 L-lysine 6-monooxygenase (NADPH-requiring)
IEKKCDLC_00976 1.41e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
IEKKCDLC_00977 1.87e-113 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IEKKCDLC_00979 4.11e-175 yhaR - - I - - - enoyl-CoA hydratase
IEKKCDLC_00980 7.01e-20 - - - S - - - YhzD-like protein
IEKKCDLC_00981 3.92e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_00982 9.73e-277 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
IEKKCDLC_00983 5.04e-298 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
IEKKCDLC_00984 0.0 yhaN - - L - - - AAA domain
IEKKCDLC_00985 2.48e-226 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
IEKKCDLC_00986 3.48e-44 yhaL - - S - - - Sporulation protein YhaL
IEKKCDLC_00987 7.58e-185 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IEKKCDLC_00988 1.29e-123 yhaK - - S - - - Putative zincin peptidase
IEKKCDLC_00989 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
IEKKCDLC_00990 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
IEKKCDLC_00991 2.74e-54 yhaH - - S - - - YtxH-like protein
IEKKCDLC_00992 2.55e-24 - - - - - - - -
IEKKCDLC_00993 1.43e-100 trpP - - S - - - Tryptophan transporter TrpP
IEKKCDLC_00994 2.81e-257 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IEKKCDLC_00995 5.82e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IEKKCDLC_00996 1.82e-174 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
IEKKCDLC_00997 2.24e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
IEKKCDLC_00998 8.65e-162 ecsC - - S - - - EcsC protein family
IEKKCDLC_00999 1.03e-284 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IEKKCDLC_01000 2.3e-310 yhfA - - C - - - membrane
IEKKCDLC_01001 3.1e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
IEKKCDLC_01002 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IEKKCDLC_01003 1.04e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IEKKCDLC_01004 5.24e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
IEKKCDLC_01005 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IEKKCDLC_01006 3.63e-130 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_01007 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
IEKKCDLC_01008 3.43e-234 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEKKCDLC_01010 3.65e-251 yhfE - - G - - - peptidase M42
IEKKCDLC_01011 3.43e-282 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IEKKCDLC_01013 1.7e-182 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IEKKCDLC_01014 6.47e-242 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
IEKKCDLC_01015 2.21e-143 yhfK - - GM - - - NmrA-like family
IEKKCDLC_01016 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IEKKCDLC_01017 2.38e-86 yhfM - - - - - - -
IEKKCDLC_01018 1.11e-301 yhfN - - O - - - Peptidase M48
IEKKCDLC_01019 3.46e-265 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IEKKCDLC_01020 1.51e-200 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IEKKCDLC_01021 7.04e-133 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
IEKKCDLC_01022 6.09e-254 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IEKKCDLC_01023 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
IEKKCDLC_01024 1.86e-116 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
IEKKCDLC_01025 1.13e-276 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
IEKKCDLC_01026 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
IEKKCDLC_01027 1.35e-204 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_01028 5.7e-44 yhzC - - S - - - IDEAL
IEKKCDLC_01029 8.93e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
IEKKCDLC_01030 1.79e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IEKKCDLC_01031 2.26e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
IEKKCDLC_01032 1.41e-119 - - - S - - - MepB protein
IEKKCDLC_01033 6.31e-163 yrpD - - S - - - Domain of unknown function, YrpD
IEKKCDLC_01034 1.23e-57 yhjA - - S - - - Excalibur calcium-binding domain
IEKKCDLC_01035 2.64e-63 - - - S - - - Belongs to the UPF0145 family
IEKKCDLC_01036 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEKKCDLC_01037 1.37e-37 yhjC - - S - - - Protein of unknown function (DUF3311)
IEKKCDLC_01038 4.12e-79 yhjD - - - - - - -
IEKKCDLC_01039 1.64e-144 yhjE - - S - - - SNARE associated Golgi protein
IEKKCDLC_01040 9.51e-119 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IEKKCDLC_01041 0.0 yhjG - - CH - - - FAD binding domain
IEKKCDLC_01042 1.7e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_01043 1.7e-262 yhjN - - S ko:K07120 - ko00000 membrane
IEKKCDLC_01044 2.27e-269 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_01045 2.72e-142 - - - K - - - QacR-like protein, C-terminal region
IEKKCDLC_01046 7.28e-122 yhjR - - S - - - Rubrerythrin
IEKKCDLC_01047 2.17e-96 ydfS - - S - - - Protein of unknown function (DUF421)
IEKKCDLC_01048 2.22e-52 ydfS - - S - - - Protein of unknown function (DUF421)
IEKKCDLC_01049 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
IEKKCDLC_01050 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
IEKKCDLC_01051 8.13e-284 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IEKKCDLC_01052 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
IEKKCDLC_01053 7.31e-65 yisB - - V - - - COG1403 Restriction endonuclease
IEKKCDLC_01054 6.66e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
IEKKCDLC_01055 1.09e-82 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
IEKKCDLC_01056 3e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
IEKKCDLC_01057 9.91e-108 gerPC - - S ko:K06301 - ko00000 Spore germination protein
IEKKCDLC_01058 6.59e-48 gerPB - - S ko:K06300 - ko00000 cell differentiation
IEKKCDLC_01059 1.28e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
IEKKCDLC_01060 2.25e-11 yisI - - S - - - Spo0E like sporulation regulatory protein
IEKKCDLC_01061 8.91e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IEKKCDLC_01062 6.36e-78 yisL - - S - - - UPF0344 protein
IEKKCDLC_01063 9.2e-125 yisN - - S - - - Protein of unknown function (DUF2777)
IEKKCDLC_01064 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IEKKCDLC_01065 2.2e-170 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
IEKKCDLC_01066 3.19e-312 yisQ - - V - - - Mate efflux family protein
IEKKCDLC_01067 5.51e-205 yisR - - K - - - Transcriptional regulator
IEKKCDLC_01068 3.11e-116 yisT - - S - - - DinB family
IEKKCDLC_01069 8.48e-96 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
IEKKCDLC_01070 5.57e-238 yisV - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEKKCDLC_01071 6.14e-108 yisX - - S - - - Pentapeptide repeats (9 copies)
IEKKCDLC_01072 3.78e-106 - - - S - - - Acetyltransferase (GNAT) domain
IEKKCDLC_01073 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IEKKCDLC_01074 6.39e-79 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
IEKKCDLC_01075 1.59e-206 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
IEKKCDLC_01076 7.61e-222 - - - S ko:K07335 - ko00000 ABC transporter substrate-binding protein PnrA-like
IEKKCDLC_01077 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IEKKCDLC_01078 5.74e-304 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
IEKKCDLC_01080 9.13e-202 yitS - - S - - - protein conserved in bacteria
IEKKCDLC_01081 1.61e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IEKKCDLC_01082 1.07e-104 ipi - - S - - - Intracellular proteinase inhibitor
IEKKCDLC_01083 1.5e-36 - - - S - - - Protein of unknown function (DUF3813)
IEKKCDLC_01084 1.49e-11 - - - - - - - -
IEKKCDLC_01085 1.52e-198 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
IEKKCDLC_01086 1.06e-186 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IEKKCDLC_01087 3.26e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
IEKKCDLC_01088 3.22e-103 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IEKKCDLC_01089 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
IEKKCDLC_01090 1.18e-121 yitZ - - G - - - Major Facilitator Superfamily
IEKKCDLC_01091 1.01e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IEKKCDLC_01092 5.39e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IEKKCDLC_01093 8.95e-176 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
IEKKCDLC_01094 3.98e-277 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
IEKKCDLC_01095 2.41e-259 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IEKKCDLC_01096 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
IEKKCDLC_01097 1.74e-226 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IEKKCDLC_01098 7.21e-39 yjzC - - S - - - YjzC-like protein
IEKKCDLC_01099 1.06e-32 yjzD - - S - - - Protein of unknown function (DUF2929)
IEKKCDLC_01100 2.14e-176 yjaU - - I - - - carboxylic ester hydrolase activity
IEKKCDLC_01101 9.68e-134 yjaV - - - - - - -
IEKKCDLC_01102 1.9e-212 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
IEKKCDLC_01103 6.46e-37 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
IEKKCDLC_01104 2.82e-44 yjzB - - - - - - -
IEKKCDLC_01105 3.78e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEKKCDLC_01106 5.48e-300 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IEKKCDLC_01107 1.84e-190 yjaZ - - O - - - Zn-dependent protease
IEKKCDLC_01108 4.15e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_01109 7.23e-238 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_01110 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
IEKKCDLC_01111 4.24e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEKKCDLC_01112 3.87e-209 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEKKCDLC_01113 5.28e-189 yjbA - - S - - - Belongs to the UPF0736 family
IEKKCDLC_01114 2.51e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
IEKKCDLC_01115 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IEKKCDLC_01116 1.46e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEKKCDLC_01117 3.59e-210 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEKKCDLC_01118 8.69e-256 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_01119 2.19e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_01120 4.26e-296 - - - S - - - Putative glycosyl hydrolase domain
IEKKCDLC_01121 4.4e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEKKCDLC_01122 2.47e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IEKKCDLC_01123 2.77e-141 yjbE - - P - - - Integral membrane protein TerC family
IEKKCDLC_01124 9.78e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IEKKCDLC_01125 2.82e-282 coiA - - S ko:K06198 - ko00000 Competence protein
IEKKCDLC_01126 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
IEKKCDLC_01127 3.14e-27 - - - - - - - -
IEKKCDLC_01128 6.05e-220 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IEKKCDLC_01129 1.22e-93 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
IEKKCDLC_01130 1.22e-149 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IEKKCDLC_01131 4.23e-129 yjbK - - S - - - protein conserved in bacteria
IEKKCDLC_01132 3.5e-81 yjbL - - S - - - Belongs to the UPF0738 family
IEKKCDLC_01133 9.01e-139 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
IEKKCDLC_01134 2.07e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEKKCDLC_01135 2.35e-211 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
IEKKCDLC_01136 2.15e-183 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IEKKCDLC_01137 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IEKKCDLC_01138 2.71e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IEKKCDLC_01139 1.63e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
IEKKCDLC_01140 4.08e-271 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
IEKKCDLC_01141 5.5e-42 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 Thiamine biosynthesis
IEKKCDLC_01142 8.58e-172 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IEKKCDLC_01143 2.25e-240 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IEKKCDLC_01144 5.24e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IEKKCDLC_01145 6.85e-180 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
IEKKCDLC_01146 2.9e-126 yjbX - - S - - - Spore coat protein
IEKKCDLC_01147 1.12e-103 cotZ - - S ko:K06344 - ko00000 Spore coat protein
IEKKCDLC_01148 1.61e-116 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
IEKKCDLC_01149 3.71e-100 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
IEKKCDLC_01150 1.37e-41 cotW - - - ko:K06341 - ko00000 -
IEKKCDLC_01151 2.67e-68 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
IEKKCDLC_01152 2.05e-73 yjcA - - S - - - Protein of unknown function (DUF1360)
IEKKCDLC_01155 5.69e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IEKKCDLC_01156 2.57e-51 spoVIF - - S - - - Stage VI sporulation protein F
IEKKCDLC_01157 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IEKKCDLC_01158 6.07e-49 - - - - - - - -
IEKKCDLC_01159 2.56e-163 blm 3.5.2.6 - S ko:K17837 ko01501,map01501 ko00000,ko00001,ko01000 Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IEKKCDLC_01160 3.77e-159 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IEKKCDLC_01161 7.12e-171 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
IEKKCDLC_01162 4.32e-48 - - - K - - - SpoVT / AbrB like domain
IEKKCDLC_01164 1.05e-97 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEKKCDLC_01165 5.73e-120 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
IEKKCDLC_01166 1.23e-164 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
IEKKCDLC_01167 1.6e-270 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IEKKCDLC_01168 3.29e-279 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IEKKCDLC_01170 0.000108 - - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
IEKKCDLC_01171 1.22e-74 - - - - - - - -
IEKKCDLC_01172 1.49e-42 - - - S - - - Bacterial EndoU nuclease
IEKKCDLC_01173 1.68e-66 - - - S - - - Bacterial EndoU nuclease
IEKKCDLC_01174 1.23e-30 - - - - - - - -
IEKKCDLC_01175 1.21e-224 - - - S - - - Bacterial EndoU nuclease
IEKKCDLC_01176 1.14e-70 - - - L ko:K21487 - ko00000,ko01000,ko02048 Belongs to the WXG100 family
IEKKCDLC_01179 9.8e-167 - - - - - - - -
IEKKCDLC_01180 9.19e-16 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IEKKCDLC_01182 7.44e-66 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
IEKKCDLC_01183 1.09e-94 - - - E - - - phosphoribosylanthranilate isomerase activity
IEKKCDLC_01185 8.5e-213 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
IEKKCDLC_01186 4.44e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
IEKKCDLC_01187 0.0 yfjF - - EGP - - - Belongs to the major facilitator superfamily
IEKKCDLC_01188 3.68e-107 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_01189 1.34e-281 yvfO 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
IEKKCDLC_01190 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IEKKCDLC_01191 5.12e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IEKKCDLC_01192 2.21e-276 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IEKKCDLC_01193 0.0 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEKKCDLC_01194 8.91e-67 celC 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_01195 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IEKKCDLC_01196 2.21e-178 yulB - - K ko:K02530 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IEKKCDLC_01197 3.55e-162 - - - S - - - Haloacid dehalogenase-like hydrolase
IEKKCDLC_01200 1.23e-136 - - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
IEKKCDLC_01202 9.12e-30 yjfB - - S - - - Putative motility protein
IEKKCDLC_01203 1.08e-92 yjgA - - T - - - Protein of unknown function (DUF2809)
IEKKCDLC_01204 4.97e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
IEKKCDLC_01205 0.0 - 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IEKKCDLC_01206 2.2e-117 yjgD - - S - - - Protein of unknown function (DUF1641)
IEKKCDLC_01207 1.54e-291 yjiB 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IEKKCDLC_01208 4.38e-286 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IEKKCDLC_01209 1e-39 - - - - - - - -
IEKKCDLC_01210 5.35e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IEKKCDLC_01211 5.95e-157 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
IEKKCDLC_01212 1.08e-166 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_01213 8.66e-229 yjlA - - EG - - - Putative multidrug resistance efflux transporter
IEKKCDLC_01214 2.1e-119 yjlB - - S - - - Cupin domain
IEKKCDLC_01215 1.7e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
IEKKCDLC_01216 7.49e-281 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IEKKCDLC_01217 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
IEKKCDLC_01218 0.0 - - - G ko:K03292 - ko00000 symporter YjmB
IEKKCDLC_01219 1.24e-235 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
IEKKCDLC_01220 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
IEKKCDLC_01221 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
IEKKCDLC_01222 3.21e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
IEKKCDLC_01223 1.02e-103 yjoA - - S - - - DinB family
IEKKCDLC_01224 2.68e-275 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IEKKCDLC_01226 2.37e-221 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
IEKKCDLC_01227 9.51e-81 yjqA - - S - - - Bacterial PH domain
IEKKCDLC_01228 6.96e-140 yjqB - - S - - - phage-related replication protein
IEKKCDLC_01229 7.99e-189 yjqC - - P ko:K07217 - ko00000 Catalase
IEKKCDLC_01230 1.87e-144 xkdA - - E - - - IrrE N-terminal-like domain
IEKKCDLC_01231 6.52e-75 xre - - K - - - Helix-turn-helix XRE-family like proteins
IEKKCDLC_01233 7.52e-197 xkdC - - L - - - Bacterial dnaA protein
IEKKCDLC_01237 1.07e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IEKKCDLC_01238 6.81e-140 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
IEKKCDLC_01239 2.75e-262 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
IEKKCDLC_01240 7.34e-304 xkdE3 - - S - - - portal protein
IEKKCDLC_01241 2.52e-118 xkdF3 - - L - - - Putative phage serine protease XkdF
IEKKCDLC_01242 8.3e-203 xkdG - - S - - - Phage capsid family
IEKKCDLC_01243 1.78e-60 yqbG - - S - - - Protein of unknown function (DUF3199)
IEKKCDLC_01244 1.66e-55 - - - S - - - Domain of unknown function (DUF3599)
IEKKCDLC_01245 1.2e-77 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
IEKKCDLC_01246 4.28e-74 xkdJ - - - - - - -
IEKKCDLC_01247 1.57e-20 - - - - - - - -
IEKKCDLC_01248 2.31e-287 xkdK - - S - - - Phage tail sheath C-terminal domain
IEKKCDLC_01249 8.21e-97 xkdM - - S - - - Phage tail tube protein
IEKKCDLC_01250 7.28e-96 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
IEKKCDLC_01251 4.33e-27 - - - - - - - -
IEKKCDLC_01252 4.06e-280 xkdO - - L - - - Transglycosylase SLT domain
IEKKCDLC_01253 6.56e-145 xkdP - - S - - - Lysin motif
IEKKCDLC_01254 1.87e-206 xkdQ - - G - - - NLP P60 protein
IEKKCDLC_01255 2.51e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
IEKKCDLC_01256 2.86e-76 xkdS - - S - - - Protein of unknown function (DUF2634)
IEKKCDLC_01257 7.58e-213 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IEKKCDLC_01258 2.48e-113 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
IEKKCDLC_01259 2.98e-36 - - - - - - - -
IEKKCDLC_01260 2.43e-229 - - - - - - - -
IEKKCDLC_01262 5.6e-41 xkdX - - - - - - -
IEKKCDLC_01263 2.48e-175 xepA - - - - - - -
IEKKCDLC_01264 3.87e-51 xhlA - - S - - - Haemolysin XhlA
IEKKCDLC_01265 4.7e-52 xhlB - - S - - - SPP1 phage holin
IEKKCDLC_01266 5.16e-217 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
IEKKCDLC_01267 2.53e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
IEKKCDLC_01268 1.89e-172 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
IEKKCDLC_01269 7.07e-226 pit - - P ko:K03306 - ko00000 phosphate transporter
IEKKCDLC_01270 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
IEKKCDLC_01271 2.3e-312 steT - - E ko:K03294 - ko00000 amino acid
IEKKCDLC_01272 2.31e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IEKKCDLC_01273 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEKKCDLC_01274 1.56e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IEKKCDLC_01276 3.91e-278 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEKKCDLC_01277 0.0 yubD - - P - - - Major Facilitator Superfamily
IEKKCDLC_01279 4.36e-200 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
IEKKCDLC_01280 1.14e-203 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEKKCDLC_01281 6.59e-227 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEKKCDLC_01282 2.26e-243 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_01283 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IEKKCDLC_01284 1.14e-225 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
IEKKCDLC_01285 5.01e-254 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
IEKKCDLC_01286 3.24e-219 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IEKKCDLC_01287 2.31e-231 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_01288 1.46e-263 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
IEKKCDLC_01289 1.71e-203 ykgA - - E - - - Amidinotransferase
IEKKCDLC_01290 8.79e-120 ykhA - - I - - - Acyl-CoA hydrolase
IEKKCDLC_01291 1.34e-132 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IEKKCDLC_01292 3.41e-69 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
IEKKCDLC_01293 1.04e-65 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
IEKKCDLC_01294 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IEKKCDLC_01295 1.07e-262 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEKKCDLC_01296 7.94e-290 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IEKKCDLC_01297 6.87e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
IEKKCDLC_01298 1.2e-111 ohrR - - K - - - COG1846 Transcriptional regulators
IEKKCDLC_01299 5.52e-92 ohrB - - O - - - Organic hydroperoxide resistance protein
IEKKCDLC_01300 3.86e-81 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IEKKCDLC_01302 5e-275 - - - M - - - Glycosyl transferase family 2
IEKKCDLC_01303 1.31e-179 - - - M - - - PFAM Collagen triple helix repeat (20 copies)
IEKKCDLC_01304 5.66e-277 - - - EGP ko:K05820 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_01305 5.8e-117 nsr - - T - - - COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IEKKCDLC_01306 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IEKKCDLC_01307 1.43e-223 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IEKKCDLC_01308 1.82e-189 yojH - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEKKCDLC_01309 1.87e-170 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
IEKKCDLC_01310 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_01311 2.31e-126 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
IEKKCDLC_01312 3.11e-310 ydhD - - M - - - Glycosyl hydrolase
IEKKCDLC_01314 5e-309 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
IEKKCDLC_01315 1.23e-69 tnrA - - K - - - transcriptional
IEKKCDLC_01316 1.11e-23 - - - - - - - -
IEKKCDLC_01317 5.25e-37 ykoL - - - - - - -
IEKKCDLC_01318 5.46e-105 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
IEKKCDLC_01319 5.41e-129 ykoP - - G - - - polysaccharide deacetylase
IEKKCDLC_01320 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
IEKKCDLC_01321 3.42e-202 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IEKKCDLC_01322 1.43e-131 ykoX - - S - - - membrane-associated protein
IEKKCDLC_01323 2.39e-172 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IEKKCDLC_01324 6.02e-163 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEKKCDLC_01325 1.03e-249 ykrI - - S - - - Anti-sigma factor N-terminus
IEKKCDLC_01326 5.7e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
IEKKCDLC_01327 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
IEKKCDLC_01328 6.35e-200 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
IEKKCDLC_01329 7.33e-306 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
IEKKCDLC_01330 3.5e-147 - - - S - - - Protein of unknown function (DUF421)
IEKKCDLC_01331 3.07e-32 ykzE - - - - - - -
IEKKCDLC_01332 2.35e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
IEKKCDLC_01333 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_01334 1.87e-113 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEKKCDLC_01336 9.34e-253 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IEKKCDLC_01337 8.52e-288 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IEKKCDLC_01338 6.67e-192 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IEKKCDLC_01339 4.42e-292 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IEKKCDLC_01340 2.73e-289 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IEKKCDLC_01341 2.71e-174 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IEKKCDLC_01342 3.05e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IEKKCDLC_01343 2.6e-124 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IEKKCDLC_01345 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IEKKCDLC_01346 1.36e-100 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
IEKKCDLC_01347 4.04e-169 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IEKKCDLC_01348 1.17e-176 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IEKKCDLC_01349 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
IEKKCDLC_01350 2.69e-232 ykvI - - S - - - membrane
IEKKCDLC_01351 1.97e-255 - - - - - - - -
IEKKCDLC_01352 2.72e-162 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IEKKCDLC_01353 8.23e-106 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
IEKKCDLC_01354 2.06e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IEKKCDLC_01355 2.56e-124 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IEKKCDLC_01356 3.36e-78 - - - K - - - HxlR-like helix-turn-helix
IEKKCDLC_01357 1.81e-170 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IEKKCDLC_01358 5.33e-25 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IEKKCDLC_01359 6.78e-269 - - - M - - - Glycosyl transferases group 1
IEKKCDLC_01360 3.08e-47 - 3.5.1.104 - M ko:K22278 - ko00000,ko01000 LysM domain
IEKKCDLC_01361 5.01e-204 - - - G - - - Glycosyl hydrolases family 18
IEKKCDLC_01363 7.02e-58 ykvR - - S - - - Protein of unknown function (DUF3219)
IEKKCDLC_01364 5.43e-35 ykvS - - S - - - protein conserved in bacteria
IEKKCDLC_01365 4.16e-38 - - - - - - - -
IEKKCDLC_01366 1.45e-142 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
IEKKCDLC_01367 2.66e-306 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEKKCDLC_01368 2.1e-114 stoA - - CO - - - thiol-disulfide
IEKKCDLC_01369 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IEKKCDLC_01370 4.04e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IEKKCDLC_01372 1.18e-223 ykvZ - - K - - - Transcriptional regulator
IEKKCDLC_01373 2.78e-199 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
IEKKCDLC_01374 0.0 ptsG 2.7.1.199 - G ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_01375 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
IEKKCDLC_01376 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEKKCDLC_01377 3.63e-50 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_01378 4.12e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
IEKKCDLC_01379 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IEKKCDLC_01380 8.11e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IEKKCDLC_01381 8.79e-170 ykwD - - J - - - protein with SCP PR1 domains
IEKKCDLC_01382 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IEKKCDLC_01383 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_01384 4.65e-275 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
IEKKCDLC_01385 6.38e-15 - - - - - - - -
IEKKCDLC_01386 1.93e-213 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
IEKKCDLC_01387 2.93e-107 ykyB - - S - - - YkyB-like protein
IEKKCDLC_01388 7.96e-309 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_01389 5.14e-116 ykuD - - S - - - protein conserved in bacteria
IEKKCDLC_01390 2.69e-199 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
IEKKCDLC_01391 4.31e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_01393 2.21e-296 ykuI - - T - - - Diguanylate phosphodiesterase
IEKKCDLC_01394 3.63e-50 ykuJ - - S - - - protein conserved in bacteria
IEKKCDLC_01395 4.35e-120 ykuK - - S ko:K09776 - ko00000 Ribonuclease H-like
IEKKCDLC_01396 3.09e-35 ykzF - - S - - - Antirepressor AbbA
IEKKCDLC_01397 8.55e-99 ykuL - - S - - - CBS domain
IEKKCDLC_01398 1.32e-215 ccpC - - K - - - Transcriptional regulator
IEKKCDLC_01399 1.28e-116 ykuN - - C ko:K03839 - ko00000 Flavodoxin
IEKKCDLC_01400 2.98e-214 ykuO - - - - - - -
IEKKCDLC_01401 5.1e-102 fld - - C ko:K03839 - ko00000 Flavodoxin
IEKKCDLC_01402 2.89e-129 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IEKKCDLC_01403 2.39e-277 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IEKKCDLC_01404 2.15e-52 ykuS - - S - - - Belongs to the UPF0180 family
IEKKCDLC_01405 2.1e-179 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
IEKKCDLC_01406 6.68e-103 ykuV - - CO - - - thiol-disulfide
IEKKCDLC_01407 7.46e-127 rok - - K - - - Repressor of ComK
IEKKCDLC_01408 2.53e-218 yknT - - - ko:K06437 - ko00000 -
IEKKCDLC_01409 4.05e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IEKKCDLC_01410 1.71e-241 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IEKKCDLC_01411 5.6e-309 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
IEKKCDLC_01412 2.64e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
IEKKCDLC_01413 2.92e-108 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
IEKKCDLC_01414 1.7e-45 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IEKKCDLC_01415 4.64e-140 yknW - - S - - - Yip1 domain
IEKKCDLC_01416 2e-246 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IEKKCDLC_01417 2.9e-158 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_01418 8.92e-271 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
IEKKCDLC_01419 2.77e-171 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_01420 4.75e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
IEKKCDLC_01421 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IEKKCDLC_01422 3.77e-138 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IEKKCDLC_01423 1.82e-50 ykoA - - - - - - -
IEKKCDLC_01424 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IEKKCDLC_01425 1.71e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEKKCDLC_01426 1.2e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
IEKKCDLC_01427 4.47e-18 - - - S - - - Uncharacterized protein YkpC
IEKKCDLC_01428 3.72e-235 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
IEKKCDLC_01429 6.37e-60 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
IEKKCDLC_01430 5.87e-313 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IEKKCDLC_01431 2.15e-196 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
IEKKCDLC_01432 9.71e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IEKKCDLC_01433 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IEKKCDLC_01434 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEKKCDLC_01435 4.45e-42 ykzG - - S - - - Belongs to the UPF0356 family
IEKKCDLC_01436 1.24e-186 ykrA - - S - - - hydrolases of the HAD superfamily
IEKKCDLC_01437 2.29e-130 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEKKCDLC_01438 7.91e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IEKKCDLC_01439 5.6e-134 ykyA - - L - - - Putative cell-wall binding lipoprotein
IEKKCDLC_01440 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IEKKCDLC_01441 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_01442 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 polyketide synthase
IEKKCDLC_01443 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_01444 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_01445 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_01446 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_01447 0.0 - - - IQ - - - Phosphopantetheine attachment site
IEKKCDLC_01448 6.73e-267 - - - V - - - Beta-lactamase
IEKKCDLC_01449 7.79e-261 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IEKKCDLC_01450 1.01e-226 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IEKKCDLC_01451 7.27e-302 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IEKKCDLC_01452 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IEKKCDLC_01453 7.97e-59 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
IEKKCDLC_01454 1.57e-189 pdaA_2 3.5.1.104 - G ko:K01567,ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IEKKCDLC_01455 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
IEKKCDLC_01456 9.4e-57 yktA - - S - - - Belongs to the UPF0223 family
IEKKCDLC_01457 7.83e-153 yktB - - S - - - Belongs to the UPF0637 family
IEKKCDLC_01458 7.89e-32 ykzI - - - - - - -
IEKKCDLC_01459 8.12e-196 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
IEKKCDLC_01460 1.3e-108 ykzC - - S - - - Acetyltransferase (GNAT) family
IEKKCDLC_01461 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
IEKKCDLC_01463 6.54e-61 ylaE - - - - - - -
IEKKCDLC_01464 5.62e-33 - - - S - - - Family of unknown function (DUF5325)
IEKKCDLC_01465 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
IEKKCDLC_01466 6.99e-65 - - - S - - - YlaH-like protein
IEKKCDLC_01467 6.78e-46 ylaI - - S - - - protein conserved in bacteria
IEKKCDLC_01468 3.84e-138 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IEKKCDLC_01469 9.42e-314 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
IEKKCDLC_01470 4.13e-109 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IEKKCDLC_01471 2.67e-223 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
IEKKCDLC_01472 1.99e-58 ylaN - - S - - - Belongs to the UPF0358 family
IEKKCDLC_01473 1.42e-270 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IEKKCDLC_01474 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IEKKCDLC_01475 1.16e-212 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IEKKCDLC_01476 2.95e-209 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IEKKCDLC_01477 3.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IEKKCDLC_01478 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEKKCDLC_01479 5.92e-142 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IEKKCDLC_01480 3.53e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IEKKCDLC_01481 8.82e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
IEKKCDLC_01482 4.12e-79 ylbA - - S - - - YugN-like family
IEKKCDLC_01483 9.59e-96 ylbB - - T - - - COG0517 FOG CBS domain
IEKKCDLC_01484 5.41e-253 ylbC - - S - - - protein with SCP PR1 domains
IEKKCDLC_01485 3.45e-86 ylbD - - S - - - Putative coat protein
IEKKCDLC_01486 1.73e-48 ylbE - - S - - - YlbE-like protein
IEKKCDLC_01487 3.33e-97 ylbF - - S - - - Belongs to the UPF0342 family
IEKKCDLC_01488 3.94e-57 ylbG - - S - - - UPF0298 protein
IEKKCDLC_01490 7.68e-116 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
IEKKCDLC_01491 8.3e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IEKKCDLC_01492 5.88e-277 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
IEKKCDLC_01493 2.48e-178 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IEKKCDLC_01494 5.31e-241 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
IEKKCDLC_01495 7.42e-295 ylbM - - S - - - Belongs to the UPF0348 family
IEKKCDLC_01496 3.3e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
IEKKCDLC_01497 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
IEKKCDLC_01498 8.95e-111 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IEKKCDLC_01499 1.14e-116 ylbP - - K - - - n-acetyltransferase
IEKKCDLC_01500 2.79e-209 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEKKCDLC_01501 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IEKKCDLC_01502 3.7e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
IEKKCDLC_01503 4.08e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IEKKCDLC_01504 1.98e-67 ftsL - - D - - - Essential cell division protein
IEKKCDLC_01505 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
IEKKCDLC_01506 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
IEKKCDLC_01507 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEKKCDLC_01508 7.04e-222 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IEKKCDLC_01509 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IEKKCDLC_01510 2.7e-236 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IEKKCDLC_01511 1.15e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IEKKCDLC_01512 9.58e-214 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
IEKKCDLC_01513 3.8e-179 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IEKKCDLC_01514 1.57e-298 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IEKKCDLC_01515 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEKKCDLC_01516 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
IEKKCDLC_01517 7.89e-216 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IEKKCDLC_01518 7.35e-161 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEKKCDLC_01519 9.33e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEKKCDLC_01520 1.97e-187 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IEKKCDLC_01521 1.67e-240 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IEKKCDLC_01522 6.11e-66 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
IEKKCDLC_01523 7.13e-52 ylmC - - S - - - sporulation protein
IEKKCDLC_01524 9.55e-206 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
IEKKCDLC_01525 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IEKKCDLC_01526 1.54e-83 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IEKKCDLC_01527 5.12e-56 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
IEKKCDLC_01528 6.12e-182 ylmH - - S - - - conserved protein, contains S4-like domain
IEKKCDLC_01529 1.85e-99 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
IEKKCDLC_01530 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEKKCDLC_01531 1.79e-84 ylyA - - T - - - COG1734 DnaK suppressor protein
IEKKCDLC_01532 3.57e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IEKKCDLC_01533 2.18e-215 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
IEKKCDLC_01534 6.32e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEKKCDLC_01535 1.39e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
IEKKCDLC_01536 1.47e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
IEKKCDLC_01537 6.34e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IEKKCDLC_01538 3.09e-268 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
IEKKCDLC_01539 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
IEKKCDLC_01540 1.01e-180 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IEKKCDLC_01541 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IEKKCDLC_01542 5.2e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IEKKCDLC_01543 4.44e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEKKCDLC_01545 9.88e-181 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
IEKKCDLC_01546 4.93e-228 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
IEKKCDLC_01547 3.72e-285 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
IEKKCDLC_01548 6.76e-143 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
IEKKCDLC_01549 3.41e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
IEKKCDLC_01550 1.02e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
IEKKCDLC_01551 2.01e-102 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
IEKKCDLC_01552 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
IEKKCDLC_01553 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
IEKKCDLC_01554 1.24e-197 yloC - - S - - - stress-induced protein
IEKKCDLC_01555 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
IEKKCDLC_01556 4.91e-144 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
IEKKCDLC_01557 2.53e-38 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IEKKCDLC_01558 4.4e-287 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEKKCDLC_01559 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEKKCDLC_01560 2.04e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEKKCDLC_01561 4.56e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IEKKCDLC_01562 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IEKKCDLC_01563 1.25e-262 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IEKKCDLC_01564 3.51e-178 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
IEKKCDLC_01565 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
IEKKCDLC_01566 1.78e-210 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IEKKCDLC_01567 1.19e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
IEKKCDLC_01568 6.42e-154 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
IEKKCDLC_01569 3.49e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
IEKKCDLC_01570 3.65e-78 yloU - - S - - - protein conserved in bacteria
IEKKCDLC_01571 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
IEKKCDLC_01572 4.15e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IEKKCDLC_01573 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
IEKKCDLC_01574 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEKKCDLC_01575 4.38e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IEKKCDLC_01576 1.81e-228 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IEKKCDLC_01577 1.31e-218 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IEKKCDLC_01578 8.61e-168 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IEKKCDLC_01579 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEKKCDLC_01580 6.09e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IEKKCDLC_01581 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
IEKKCDLC_01582 1.87e-224 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IEKKCDLC_01583 7.14e-181 - - - S - - - Phosphotransferase enzyme family
IEKKCDLC_01584 1.97e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IEKKCDLC_01585 3.46e-302 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEKKCDLC_01586 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
IEKKCDLC_01587 4.9e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
IEKKCDLC_01588 1.39e-79 ylqD - - S - - - YlqD protein
IEKKCDLC_01589 1.51e-121 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEKKCDLC_01590 8.4e-178 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
IEKKCDLC_01591 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IEKKCDLC_01592 7.24e-203 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IEKKCDLC_01593 8.29e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEKKCDLC_01594 0.0 ylqG - - - - - - -
IEKKCDLC_01595 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
IEKKCDLC_01596 2.02e-270 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IEKKCDLC_01597 7.59e-214 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IEKKCDLC_01598 5.15e-216 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
IEKKCDLC_01599 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEKKCDLC_01600 1.1e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IEKKCDLC_01601 6.29e-220 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
IEKKCDLC_01602 7.38e-121 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IEKKCDLC_01603 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IEKKCDLC_01604 2.77e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IEKKCDLC_01605 2.8e-84 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IEKKCDLC_01606 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
IEKKCDLC_01607 1.51e-50 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
IEKKCDLC_01608 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
IEKKCDLC_01609 2.48e-229 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IEKKCDLC_01610 5.36e-120 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
IEKKCDLC_01611 1.74e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IEKKCDLC_01612 2.17e-92 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
IEKKCDLC_01613 3.43e-89 ylxF - - S - - - MgtE intracellular N domain
IEKKCDLC_01614 3e-260 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
IEKKCDLC_01615 8.9e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
IEKKCDLC_01616 2.79e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
IEKKCDLC_01617 7.7e-80 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
IEKKCDLC_01618 5.43e-230 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IEKKCDLC_01619 1.21e-247 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IEKKCDLC_01620 2.12e-77 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
IEKKCDLC_01621 9.34e-144 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
IEKKCDLC_01622 6.02e-142 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
IEKKCDLC_01623 3.15e-51 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
IEKKCDLC_01624 2.84e-168 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
IEKKCDLC_01625 2.53e-242 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IEKKCDLC_01626 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IEKKCDLC_01627 6.52e-249 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
IEKKCDLC_01628 3.15e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
IEKKCDLC_01629 2.02e-248 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IEKKCDLC_01630 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
IEKKCDLC_01631 2.49e-105 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
IEKKCDLC_01632 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IEKKCDLC_01633 8.2e-113 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IEKKCDLC_01634 3.96e-177 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEKKCDLC_01635 7.41e-97 ylxL - - - - - - -
IEKKCDLC_01636 1.74e-167 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
IEKKCDLC_01637 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IEKKCDLC_01638 7.09e-164 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
IEKKCDLC_01639 1.94e-118 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IEKKCDLC_01640 2.22e-186 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEKKCDLC_01641 3.8e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
IEKKCDLC_01642 1.55e-273 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IEKKCDLC_01643 1.15e-296 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
IEKKCDLC_01644 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IEKKCDLC_01645 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEKKCDLC_01646 5.66e-106 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
IEKKCDLC_01647 4.04e-264 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
IEKKCDLC_01648 6.76e-56 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
IEKKCDLC_01649 6.16e-63 ylxQ - - J - - - ribosomal protein
IEKKCDLC_01650 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IEKKCDLC_01651 3.88e-60 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
IEKKCDLC_01652 1.03e-73 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEKKCDLC_01653 1.42e-218 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEKKCDLC_01654 3.69e-232 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
IEKKCDLC_01655 4.12e-56 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IEKKCDLC_01656 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IEKKCDLC_01657 2.06e-232 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
IEKKCDLC_01658 2.51e-300 mlpA - - S - - - Belongs to the peptidase M16 family
IEKKCDLC_01659 2.17e-56 ymxH - - S - - - YlmC YmxH family
IEKKCDLC_01660 1.91e-205 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
IEKKCDLC_01661 4.75e-138 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IEKKCDLC_01662 2.03e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IEKKCDLC_01663 2e-282 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IEKKCDLC_01664 7.2e-202 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEKKCDLC_01665 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEKKCDLC_01666 1.08e-164 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
IEKKCDLC_01667 6.32e-42 - - - S - - - YlzJ-like protein
IEKKCDLC_01668 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IEKKCDLC_01669 4.48e-172 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_01670 9.04e-296 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_01671 9.88e-100 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_01672 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
IEKKCDLC_01673 3.22e-306 albE - - S - - - Peptidase M16
IEKKCDLC_01674 2.37e-309 ymfH - - S - - - zinc protease
IEKKCDLC_01675 1.43e-164 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IEKKCDLC_01676 6.23e-56 ymfJ - - S - - - Protein of unknown function (DUF3243)
IEKKCDLC_01677 3.82e-184 ymfK - - S - - - Protein of unknown function (DUF3388)
IEKKCDLC_01678 1.17e-178 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
IEKKCDLC_01679 1.17e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEKKCDLC_01680 3.27e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
IEKKCDLC_01681 3.42e-236 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IEKKCDLC_01682 5.46e-279 pbpX - - V - - - Beta-lactamase
IEKKCDLC_01683 2.91e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
IEKKCDLC_01684 3.72e-196 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
IEKKCDLC_01685 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
IEKKCDLC_01686 6.82e-250 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IEKKCDLC_01687 4.29e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IEKKCDLC_01688 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IEKKCDLC_01689 2.11e-88 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
IEKKCDLC_01690 7.09e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
IEKKCDLC_01691 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IEKKCDLC_01692 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IEKKCDLC_01693 4.34e-64 - - - L - - - Belongs to the 'phage' integrase family
IEKKCDLC_01694 3.97e-49 - - - - - - - -
IEKKCDLC_01697 4.05e-166 pksB 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 Polyketide biosynthesis
IEKKCDLC_01698 4.05e-208 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IEKKCDLC_01699 4.5e-234 pksD - - Q ko:K15328 - ko00000,ko01008 Acyl transferase domain
IEKKCDLC_01700 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IEKKCDLC_01701 2.51e-47 acpK - - IQ ko:K15337 - ko00000,ko01008 Phosphopantetheine attachment site
IEKKCDLC_01702 3.63e-309 pksG 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IEKKCDLC_01703 4.33e-187 - - - I ko:K15312 - ko00000,ko01008 enoyl-CoA hydratase
IEKKCDLC_01704 3.42e-180 pksI - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IEKKCDLC_01705 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IEKKCDLC_01706 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_01707 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_01708 0.0 - - - IQ ko:K13611,ko:K13614 - ko00000,ko01004,ko01008 polyketide synthase
IEKKCDLC_01709 0.0 - - - HQ ko:K13615 - ko00000,ko01004,ko01008 Beta-ketoacyl synthase
IEKKCDLC_01710 1.13e-292 cypA 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IEKKCDLC_01711 2.57e-103 nucB - - M - - - Deoxyribonuclease NucA/NucB
IEKKCDLC_01712 1.28e-152 yoaK - - S - - - Membrane
IEKKCDLC_01713 5.4e-80 ymzB - - - - - - -
IEKKCDLC_01714 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
IEKKCDLC_01715 3.03e-06 - - - - - - - -
IEKKCDLC_01716 6.85e-164 ymaC - - S - - - Replication protein
IEKKCDLC_01717 1.71e-104 ymaD - - O - - - redox protein, regulator of disulfide bond formation
IEKKCDLC_01718 7.46e-72 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IEKKCDLC_01719 1.82e-63 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
IEKKCDLC_01721 5.96e-77 ymaF - - S - - - YmaF family
IEKKCDLC_01722 7.63e-221 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IEKKCDLC_01723 9e-46 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IEKKCDLC_01724 9.98e-58 - - - - - - - -
IEKKCDLC_01725 9.42e-29 ymzA - - - - - - -
IEKKCDLC_01726 9.34e-88 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
IEKKCDLC_01727 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEKKCDLC_01728 5.77e-244 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEKKCDLC_01729 3.18e-141 ymaB - - S - - - MutT family
IEKKCDLC_01730 1.07e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IEKKCDLC_01731 1.55e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
IEKKCDLC_01732 2.21e-294 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEKKCDLC_01733 4.1e-311 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IEKKCDLC_01734 5.34e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
IEKKCDLC_01735 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
IEKKCDLC_01737 8.75e-42 - - - - - - - -
IEKKCDLC_01738 5.15e-117 yokH - - G - - - SMI1 / KNR4 family
IEKKCDLC_01739 1.55e-282 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IEKKCDLC_01740 2.13e-65 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IEKKCDLC_01741 3.78e-84 yokK - - S - - - SMI1 / KNR4 family
IEKKCDLC_01742 3.09e-268 mrjp - - G - - - Major royal jelly protein
IEKKCDLC_01743 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
IEKKCDLC_01744 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IEKKCDLC_01745 7.75e-279 xylR - - GK - - - ROK family
IEKKCDLC_01746 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
IEKKCDLC_01747 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
IEKKCDLC_01748 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
IEKKCDLC_01751 2.21e-27 - - - - - - - -
IEKKCDLC_01752 1.2e-72 dinB - - S - - - DinB family
IEKKCDLC_01753 5.08e-238 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
IEKKCDLC_01754 1.14e-10 - - - S - - - Bacterial transferase hexapeptide (six repeats)
IEKKCDLC_01755 6.73e-23 - - - - - - - -
IEKKCDLC_01756 2.86e-26 yoaW - - - - - - -
IEKKCDLC_01757 4.33e-05 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IEKKCDLC_01758 6.56e-181 yoaP - - K - - - YoaP-like
IEKKCDLC_01759 3.94e-103 - - - J - - - Acetyltransferase (GNAT) domain
IEKKCDLC_01760 2.01e-153 - - - S - - - Domain of unknown function (DUF3885)
IEKKCDLC_01761 4.85e-257 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEKKCDLC_01762 1.65e-152 - - AA10,CBM73 S ko:K03933 - ko00000 Pfam:Chitin_bind_3
IEKKCDLC_01763 9.28e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
IEKKCDLC_01764 7.48e-85 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
IEKKCDLC_01765 4.49e-125 yvgO - - - - - - -
IEKKCDLC_01767 0.0 yobO - - M - - - Pectate lyase superfamily protein
IEKKCDLC_01768 1.49e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
IEKKCDLC_01769 2.12e-186 yndL - - S - - - Replication protein
IEKKCDLC_01770 1.74e-11 - - - - - - - -
IEKKCDLC_01771 4.43e-185 - - - O - - - COG0330 Membrane protease subunits, stomatin prohibitin homologs
IEKKCDLC_01772 3.2e-95 yndM - - S - - - Protein of unknown function (DUF2512)
IEKKCDLC_01774 3.18e-141 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEKKCDLC_01775 1.01e-67 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IEKKCDLC_01776 5.22e-145 yneB - - L - - - resolvase
IEKKCDLC_01777 2.33e-43 ynzC - - S - - - UPF0291 protein
IEKKCDLC_01778 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IEKKCDLC_01779 1.08e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
IEKKCDLC_01780 6.2e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
IEKKCDLC_01781 1.97e-33 ynzD - - S - - - Spo0E like sporulation regulatory protein
IEKKCDLC_01782 4.47e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
IEKKCDLC_01783 7.09e-76 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
IEKKCDLC_01784 2.27e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
IEKKCDLC_01785 1.18e-98 yneK - - S - - - Protein of unknown function (DUF2621)
IEKKCDLC_01786 7.01e-82 cotM - - O ko:K06335 - ko00000 Spore coat protein
IEKKCDLC_01787 1.97e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
IEKKCDLC_01788 6.2e-22 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
IEKKCDLC_01789 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IEKKCDLC_01790 3.46e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IEKKCDLC_01792 1e-43 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
IEKKCDLC_01793 2.94e-97 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
IEKKCDLC_01794 1.34e-70 yneQ - - - - - - -
IEKKCDLC_01795 2.67e-66 yneR - - S - - - Belongs to the HesB IscA family
IEKKCDLC_01796 9.09e-121 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IEKKCDLC_01797 9.94e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
IEKKCDLC_01798 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEKKCDLC_01799 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEKKCDLC_01800 3.14e-19 - - - - - - - -
IEKKCDLC_01801 1.82e-63 ynfC - - - - - - -
IEKKCDLC_01802 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
IEKKCDLC_01803 2.49e-228 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
IEKKCDLC_01804 8.49e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
IEKKCDLC_01805 1.84e-147 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
IEKKCDLC_01806 1.55e-268 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
IEKKCDLC_01807 1.06e-193 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_01808 1.5e-232 regR - - K ko:K02525 - ko00000,ko03000 transcriptional
IEKKCDLC_01809 3.21e-286 exuT - - G ko:K08191,ko:K08194 - ko00000,ko02000 Sugar (and other) transporter
IEKKCDLC_01810 2e-199 yndG - - S - - - DoxX-like family
IEKKCDLC_01811 1.83e-98 - - - S - - - Domain of unknown function (DUF4166)
IEKKCDLC_01812 0.0 yndJ - - S - - - YndJ-like protein
IEKKCDLC_01813 3.68e-273 - - - S - - - Platelet-activating factor acetylhydrolase, isoform II
IEKKCDLC_01814 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
IEKKCDLC_01815 4.26e-69 yvlA - - S - - - Domain of unknown function (DUF4870)
IEKKCDLC_01816 3.27e-310 - - - T - - - Histidine kinase
IEKKCDLC_01817 1.88e-164 - - - T - - - Transcriptional regulatory protein, C terminal
IEKKCDLC_01818 1.77e-315 ynfF 3.2.1.136 GH5 G ko:K15924 - ko00000,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IEKKCDLC_01819 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
IEKKCDLC_01820 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_01821 0.0 - - - Q ko:K15662,ko:K15663 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_01822 0.0 nrsA - - Q ko:K15661 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_01823 1.34e-278 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IEKKCDLC_01824 9.66e-177 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IEKKCDLC_01825 4.5e-157 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IEKKCDLC_01826 2.98e-160 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEKKCDLC_01827 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
IEKKCDLC_01828 2.25e-285 bioI 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IEKKCDLC_01829 3.22e-246 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IEKKCDLC_01830 1.5e-166 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IEKKCDLC_01831 3.39e-274 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IEKKCDLC_01832 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IEKKCDLC_01833 1.34e-185 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IEKKCDLC_01834 2.26e-95 yngA - - S - - - membrane
IEKKCDLC_01835 1.25e-206 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IEKKCDLC_01836 5.33e-135 yngC - - S - - - SNARE associated Golgi protein
IEKKCDLC_01837 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IEKKCDLC_01838 2.48e-178 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
IEKKCDLC_01839 6.01e-215 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
IEKKCDLC_01840 2.77e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
IEKKCDLC_01841 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
IEKKCDLC_01842 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IEKKCDLC_01843 5.35e-268 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IEKKCDLC_01844 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
IEKKCDLC_01845 1.67e-85 yngL - - S - - - Protein of unknown function (DUF1360)
IEKKCDLC_01846 0.0 - - - Q ko:K15656,ko:K15668 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 D-alanine [D-alanyl carrier protein] ligase activity
IEKKCDLC_01847 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_01848 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_01849 0.0 - - - Q ko:K15665 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_01850 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_01851 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
IEKKCDLC_01852 2.25e-238 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
IEKKCDLC_01853 7.44e-312 yoeA - - V - - - MATE efflux family protein
IEKKCDLC_01854 2.13e-124 yoeB - - S - - - IseA DL-endopeptidase inhibitor
IEKKCDLC_01856 3.97e-125 - - - L - - - Integrase
IEKKCDLC_01857 6.69e-47 yoeD - - G - - - Helix-turn-helix domain
IEKKCDLC_01858 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IEKKCDLC_01859 1.38e-255 - - - EGP ko:K08164 - ko00000,ko02000 -transporter
IEKKCDLC_01860 3.29e-67 - - - K - - - Helix-turn-helix domain
IEKKCDLC_01861 1.23e-17 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEKKCDLC_01862 1.97e-196 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_01863 1.7e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IEKKCDLC_01864 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IEKKCDLC_01865 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
IEKKCDLC_01866 3.04e-204 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_01867 8.07e-259 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IEKKCDLC_01868 2.81e-180 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEKKCDLC_01869 8.13e-82 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IEKKCDLC_01870 3.49e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_01871 1.15e-54 - - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEKKCDLC_01872 1.56e-178 yoxB - - - - - - -
IEKKCDLC_01873 7.72e-262 yoaB - - EGP - - - the major facilitator superfamily
IEKKCDLC_01874 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
IEKKCDLC_01875 6.27e-248 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEKKCDLC_01876 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEKKCDLC_01877 8.56e-34 yoaF - - - - - - -
IEKKCDLC_01879 7.75e-127 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_01880 9.86e-59 - - - - - - - -
IEKKCDLC_01881 3.86e-112 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
IEKKCDLC_01882 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IEKKCDLC_01883 2.12e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
IEKKCDLC_01884 3.17e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
IEKKCDLC_01885 1.86e-122 yobS - - K - - - Transcriptional regulator
IEKKCDLC_01886 1.82e-170 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IEKKCDLC_01887 2.72e-119 yobW - - - - - - -
IEKKCDLC_01888 7.69e-73 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
IEKKCDLC_01889 1.19e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IEKKCDLC_01890 1.33e-117 yozB - - S ko:K08976 - ko00000 membrane
IEKKCDLC_01891 1.1e-182 - - - J - - - Protein required for attachment to host cells
IEKKCDLC_01892 1.87e-122 yocC - - - - - - -
IEKKCDLC_01893 1.35e-240 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
IEKKCDLC_01895 9.79e-168 yocH - - M - - - COG1388 FOG LysM repeat
IEKKCDLC_01896 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IEKKCDLC_01897 2.32e-144 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEKKCDLC_01899 4.5e-79 yocK - - T - - - general stress protein
IEKKCDLC_01900 2.71e-13 yocL - - - - - - -
IEKKCDLC_01901 3.51e-13 yocN - - - - - - -
IEKKCDLC_01902 2.29e-116 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IEKKCDLC_01903 5.58e-59 yozN - - - - - - -
IEKKCDLC_01904 6.36e-50 yocN - - - - - - -
IEKKCDLC_01905 5.32e-75 yozO - - S - - - Bacterial PH domain
IEKKCDLC_01907 4.69e-43 yozC - - - - - - -
IEKKCDLC_01908 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IEKKCDLC_01909 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
IEKKCDLC_01910 4.76e-212 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
IEKKCDLC_01911 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IEKKCDLC_01912 9.85e-215 yocS - - S ko:K03453 - ko00000 -transporter
IEKKCDLC_01913 6.38e-180 - - - S - - - Metallo-beta-lactamase superfamily
IEKKCDLC_01914 4.28e-262 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IEKKCDLC_01915 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IEKKCDLC_01916 0.0 yojO - - P - - - Von Willebrand factor
IEKKCDLC_01917 1.2e-208 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
IEKKCDLC_01918 1.08e-143 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IEKKCDLC_01919 2.48e-292 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
IEKKCDLC_01920 7.02e-287 - - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
IEKKCDLC_01921 9.47e-144 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEKKCDLC_01923 2.29e-308 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
IEKKCDLC_01924 1.44e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEKKCDLC_01925 1.57e-162 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
IEKKCDLC_01926 8.09e-80 yojF - - S - - - Protein of unknown function (DUF1806)
IEKKCDLC_01927 1.05e-30 - - - - - - - -
IEKKCDLC_01928 2.43e-209 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
IEKKCDLC_01929 1.1e-102 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
IEKKCDLC_01931 2.59e-89 iolK - - S - - - tautomerase
IEKKCDLC_01932 3.21e-91 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
IEKKCDLC_01933 2.42e-74 yodB - - K - - - transcriptional
IEKKCDLC_01934 1.11e-137 yodC - - C - - - nitroreductase
IEKKCDLC_01935 2.43e-140 yahD - - S ko:K06999 - ko00000 Carboxylesterase
IEKKCDLC_01936 8.94e-221 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
IEKKCDLC_01937 1.97e-28 - - - S - - - Protein of unknown function (DUF3311)
IEKKCDLC_01938 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEKKCDLC_01939 0.0 - 3.2.1.45 GH30 M ko:K01201 ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142 ko00000,ko00001,ko01000 Glycosyl hydrolase family 30 beta sandwich domain
IEKKCDLC_01940 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IEKKCDLC_01941 2.49e-169 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_01942 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IEKKCDLC_01943 1.76e-165 yodH - - Q - - - Methyltransferase
IEKKCDLC_01944 6.87e-50 yodI - - - - - - -
IEKKCDLC_01945 7.76e-193 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
IEKKCDLC_01946 1.05e-161 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
IEKKCDLC_01948 1.16e-72 yodL - - S - - - YodL-like
IEKKCDLC_01949 9.08e-135 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
IEKKCDLC_01950 9.77e-34 yozD - - S - - - YozD-like protein
IEKKCDLC_01952 7.75e-161 yodN - - - - - - -
IEKKCDLC_01953 2.45e-48 yozE - - S - - - Belongs to the UPF0346 family
IEKKCDLC_01954 4.89e-63 yokU - - S - - - YokU-like protein, putative antitoxin
IEKKCDLC_01955 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
IEKKCDLC_01956 2.95e-205 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
IEKKCDLC_01957 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
IEKKCDLC_01958 1.28e-157 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IEKKCDLC_01959 6.87e-161 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IEKKCDLC_01960 9.76e-312 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IEKKCDLC_01961 5.88e-84 - - - L - - - Bacterial transcription activator, effector binding domain
IEKKCDLC_01963 4.02e-185 yiiD - - K ko:K06323 - ko00000 acetyltransferase
IEKKCDLC_01964 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
IEKKCDLC_01965 3.32e-62 cgeC - - - ko:K06321 - ko00000 -
IEKKCDLC_01966 1.55e-90 cgeA - - - ko:K06319 - ko00000 -
IEKKCDLC_01967 2.22e-231 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
IEKKCDLC_01968 6.14e-280 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
IEKKCDLC_01969 3.54e-95 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IEKKCDLC_01975 3.1e-100 - - - - - - - -
IEKKCDLC_01979 2.25e-100 yoqH - - M - - - LysM domain
IEKKCDLC_01980 1.8e-250 - - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IEKKCDLC_01982 1.19e-51 - - - H - - - Acetyltransferase (GNAT) domain
IEKKCDLC_01983 2.89e-109 yokK - - S - - - SMI1 / KNR4 family
IEKKCDLC_01984 2.11e-126 - - - S - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
IEKKCDLC_01985 6.71e-83 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IEKKCDLC_01986 1.73e-108 - - - G - - - SMI1-KNR4 cell-wall
IEKKCDLC_01987 3.94e-22 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
IEKKCDLC_01988 0.0 yokA - - L - - - Recombinase
IEKKCDLC_01989 1.02e-135 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IEKKCDLC_01990 4.61e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
IEKKCDLC_01991 1.2e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEKKCDLC_01992 3.35e-89 ypoP - - K - - - transcriptional
IEKKCDLC_01993 9.66e-127 ypmS - - S - - - protein conserved in bacteria
IEKKCDLC_01994 4.29e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
IEKKCDLC_01995 1.84e-145 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IEKKCDLC_01996 8.98e-55 ypmP - - S - - - Protein of unknown function (DUF2535)
IEKKCDLC_01997 4.25e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IEKKCDLC_01998 2.57e-227 yplP - - K - - - Transcriptional regulator
IEKKCDLC_01999 7.44e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
IEKKCDLC_02000 1.41e-149 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IEKKCDLC_02001 3.01e-117 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEKKCDLC_02002 1.78e-203 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEKKCDLC_02003 6.48e-148 ypjP - - S - - - YpjP-like protein
IEKKCDLC_02004 1e-171 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
IEKKCDLC_02005 1.96e-98 yphP - - S - - - Belongs to the UPF0403 family
IEKKCDLC_02006 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
IEKKCDLC_02007 4.02e-204 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
IEKKCDLC_02008 1.61e-128 yagB - - S ko:K06950 - ko00000 phosphohydrolase
IEKKCDLC_02009 3.93e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
IEKKCDLC_02010 2.3e-227 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IEKKCDLC_02011 1.56e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IEKKCDLC_02012 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
IEKKCDLC_02013 1.27e-17 degR - - - - - - -
IEKKCDLC_02014 1.13e-49 - - - S - - - Protein of unknown function (DUF2564)
IEKKCDLC_02015 3.82e-39 ypeQ - - S - - - Zinc-finger
IEKKCDLC_02016 5.91e-159 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
IEKKCDLC_02017 9.33e-153 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IEKKCDLC_02018 2.11e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
IEKKCDLC_02020 3.33e-210 ypcP - - L - - - 5'3' exonuclease
IEKKCDLC_02021 2.44e-10 - - - - - - - -
IEKKCDLC_02022 4.07e-52 ypbS - - S - - - Protein of unknown function (DUF2533)
IEKKCDLC_02023 0.0 ypbR - - S - - - Dynamin family
IEKKCDLC_02024 1.26e-117 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
IEKKCDLC_02025 1.41e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
IEKKCDLC_02026 8.77e-137 - - - J - - - Acetyltransferase (GNAT) domain
IEKKCDLC_02027 6.34e-66 MGMT - - L ko:K07443 - ko00000 6-O-methylguanine DNA methyltransferase, DNA binding domain
IEKKCDLC_02028 1.21e-08 - - - S - - - Bacillus cereus group antimicrobial protein
IEKKCDLC_02029 3.74e-44 ydfR - - S - - - Protein of unknown function (DUF421)
IEKKCDLC_02030 1.89e-44 ydfR - - S - - - Protein of unknown function (DUF421)
IEKKCDLC_02031 1.04e-128 yrdC - - Q - - - Isochorismatase family
IEKKCDLC_02032 2.23e-07 - - - S - - - Bacillus cereus group antimicrobial protein
IEKKCDLC_02033 2.06e-297 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine
IEKKCDLC_02034 1.16e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IEKKCDLC_02035 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IEKKCDLC_02036 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
IEKKCDLC_02038 6.91e-31 - - - S - - - YpzG-like protein
IEKKCDLC_02039 4.68e-276 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
IEKKCDLC_02040 5.52e-61 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IEKKCDLC_02041 7.71e-128 ypsA - - S - - - Belongs to the UPF0398 family
IEKKCDLC_02042 9.36e-48 cotD - - S ko:K06327 - ko00000 Inner spore coat protein D
IEKKCDLC_02043 6.67e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
IEKKCDLC_02044 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IEKKCDLC_02045 1.21e-115 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
IEKKCDLC_02046 4.19e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
IEKKCDLC_02047 3.33e-81 yppG - - S - - - YppG-like protein
IEKKCDLC_02051 0.000542 - - - - ko:K06430 - ko00000 -
IEKKCDLC_02052 4.04e-239 yppC - - S - - - Protein of unknown function (DUF2515)
IEKKCDLC_02053 8.84e-146 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IEKKCDLC_02054 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IEKKCDLC_02055 1.43e-116 ypoC - - - - - - -
IEKKCDLC_02056 1.7e-156 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEKKCDLC_02057 3.42e-167 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
IEKKCDLC_02058 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
IEKKCDLC_02059 1.2e-282 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
IEKKCDLC_02060 9.65e-105 ypmB - - S - - - protein conserved in bacteria
IEKKCDLC_02061 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
IEKKCDLC_02062 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
IEKKCDLC_02063 2.41e-84 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IEKKCDLC_02064 3.44e-203 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IEKKCDLC_02065 9.39e-192 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IEKKCDLC_02066 3.67e-229 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IEKKCDLC_02067 6.9e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IEKKCDLC_02068 3.63e-269 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
IEKKCDLC_02069 2.59e-169 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
IEKKCDLC_02070 6.19e-94 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
IEKKCDLC_02071 9.78e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IEKKCDLC_02072 2.47e-74 ypjD - - S - - - Nucleotide pyrophosphohydrolase
IEKKCDLC_02073 4.31e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IEKKCDLC_02074 1.16e-288 - 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IEKKCDLC_02075 2.05e-182 ypjB - - S - - - sporulation protein
IEKKCDLC_02076 9.19e-137 ypjA - - S - - - membrane
IEKKCDLC_02077 4.02e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
IEKKCDLC_02078 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
IEKKCDLC_02079 2.86e-127 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
IEKKCDLC_02080 2.35e-101 ypiF - - S - - - Protein of unknown function (DUF2487)
IEKKCDLC_02081 1.06e-128 ypiB - - S - - - Belongs to the UPF0302 family
IEKKCDLC_02082 4.33e-298 ypiA - - S - - - COG0457 FOG TPR repeat
IEKKCDLC_02083 1.31e-134 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
IEKKCDLC_02084 2.12e-70 - - - L - - - COG2963 Transposase and inactivated derivatives
IEKKCDLC_02085 4.91e-302 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IEKKCDLC_02086 1.24e-260 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
IEKKCDLC_02087 4.31e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IEKKCDLC_02088 4.65e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IEKKCDLC_02089 6.04e-291 trpB 4.2.1.20 - E ko:K01696 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IEKKCDLC_02090 9.06e-151 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
IEKKCDLC_02091 4.97e-169 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
IEKKCDLC_02092 8.27e-212 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IEKKCDLC_02093 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IEKKCDLC_02094 2.93e-79 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IEKKCDLC_02095 7.79e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IEKKCDLC_02096 9.75e-276 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IEKKCDLC_02097 3.54e-181 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
IEKKCDLC_02098 2.35e-101 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IEKKCDLC_02099 2.29e-251 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IEKKCDLC_02100 7.76e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IEKKCDLC_02101 3.96e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IEKKCDLC_02102 6.23e-47 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IEKKCDLC_02103 6.27e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
IEKKCDLC_02104 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IEKKCDLC_02105 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IEKKCDLC_02106 5.64e-172 yphF - - - - - - -
IEKKCDLC_02107 3.25e-23 yphE - - S - - - Protein of unknown function (DUF2768)
IEKKCDLC_02108 4.93e-244 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
IEKKCDLC_02109 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
IEKKCDLC_02110 3.58e-135 yphA - - - - - - -
IEKKCDLC_02111 1.87e-12 - - - S - - - YpzI-like protein
IEKKCDLC_02112 1.33e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IEKKCDLC_02113 8.14e-264 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
IEKKCDLC_02114 2.02e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
IEKKCDLC_02115 7.86e-18 - - - S - - - Family of unknown function (DUF5359)
IEKKCDLC_02116 4.07e-78 ypfA - - M - - - Flagellar protein YcgR
IEKKCDLC_02117 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
IEKKCDLC_02118 3.77e-213 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
IEKKCDLC_02119 6.4e-156 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
IEKKCDLC_02120 1.07e-238 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
IEKKCDLC_02121 1.81e-311 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IEKKCDLC_02122 3.35e-137 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IEKKCDLC_02123 4.68e-189 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
IEKKCDLC_02124 1.92e-111 ypbF - - S - - - Protein of unknown function (DUF2663)
IEKKCDLC_02125 2.5e-133 ypbE - - M - - - Lysin motif
IEKKCDLC_02126 1.09e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
IEKKCDLC_02127 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
IEKKCDLC_02128 3.02e-253 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
IEKKCDLC_02129 5.88e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
IEKKCDLC_02130 6.2e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IEKKCDLC_02131 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEKKCDLC_02132 2.02e-249 rsiX - - - - - - -
IEKKCDLC_02133 3.22e-135 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
IEKKCDLC_02134 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_02135 9.77e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_02136 4.39e-252 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IEKKCDLC_02137 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
IEKKCDLC_02138 4.31e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IEKKCDLC_02139 1.49e-167 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IEKKCDLC_02140 3.66e-115 spmB - - S ko:K06374 - ko00000 Spore maturation protein
IEKKCDLC_02141 3.75e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
IEKKCDLC_02142 7.36e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IEKKCDLC_02143 6.14e-122 ypuI - - S - - - Protein of unknown function (DUF3907)
IEKKCDLC_02144 2.73e-133 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEKKCDLC_02145 2.09e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEKKCDLC_02147 2.33e-120 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
IEKKCDLC_02148 2.74e-84 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEKKCDLC_02149 6.92e-106 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IEKKCDLC_02150 7.34e-291 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IEKKCDLC_02151 1.55e-141 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
IEKKCDLC_02152 1.53e-267 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEKKCDLC_02153 4.92e-71 ypuD - - - - - - -
IEKKCDLC_02154 3.8e-130 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
IEKKCDLC_02155 1.36e-105 ccdC1 - - O - - - Protein of unknown function (DUF1453)
IEKKCDLC_02156 4.12e-104 ppiB 5.2.1.8 - O ko:K01802,ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IEKKCDLC_02157 6.31e-199 ypuA - - S - - - Secreted protein
IEKKCDLC_02158 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IEKKCDLC_02159 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
IEKKCDLC_02160 1.31e-142 - - - S ko:K06407 - ko00000 stage V sporulation protein
IEKKCDLC_02161 1.51e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
IEKKCDLC_02162 8.19e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
IEKKCDLC_02163 9.92e-104 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
IEKKCDLC_02164 1.43e-78 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
IEKKCDLC_02165 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
IEKKCDLC_02166 6.81e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEKKCDLC_02167 4.77e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IEKKCDLC_02168 4.86e-77 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
IEKKCDLC_02169 1.67e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
IEKKCDLC_02170 1.1e-192 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IEKKCDLC_02171 4.97e-294 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
IEKKCDLC_02172 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
IEKKCDLC_02173 9.51e-51 - - - S - - - Protein of unknown function (DUF4227)
IEKKCDLC_02174 4.56e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
IEKKCDLC_02175 8.31e-141 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IEKKCDLC_02176 1.79e-46 yqkK - - - - - - -
IEKKCDLC_02177 6.84e-31 - - - - - - - -
IEKKCDLC_02178 8.31e-310 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IEKKCDLC_02179 2.15e-314 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IEKKCDLC_02180 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
IEKKCDLC_02181 5.31e-240 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
IEKKCDLC_02182 1.15e-75 ansR - - K - - - Transcriptional regulator
IEKKCDLC_02183 1.45e-280 yqxK - - L - - - DNA helicase
IEKKCDLC_02184 1.04e-122 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
IEKKCDLC_02185 2.01e-10 - - - S - - - Protein of unknown function (DUF3936)
IEKKCDLC_02186 5.13e-215 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IEKKCDLC_02187 1.45e-11 yqkE - - S - - - Protein of unknown function (DUF3886)
IEKKCDLC_02188 6.77e-225 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
IEKKCDLC_02189 7.88e-54 yqkC - - S - - - Protein of unknown function (DUF2552)
IEKKCDLC_02190 5.4e-80 yqkB - - S - - - Belongs to the HesB IscA family
IEKKCDLC_02191 1.44e-223 yqkA - - K - - - GrpB protein
IEKKCDLC_02192 1.71e-80 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
IEKKCDLC_02193 2.81e-115 yqjY - - K ko:K06977 - ko00000 acetyltransferase
IEKKCDLC_02194 4.67e-299 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEKKCDLC_02195 1.12e-76 - - - S - - - YolD-like protein
IEKKCDLC_02197 4.13e-238 yueF - - S - - - transporter activity
IEKKCDLC_02199 7.67e-96 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEKKCDLC_02200 4.46e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
IEKKCDLC_02201 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
IEKKCDLC_02202 3.39e-180 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_02203 6.83e-224 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IEKKCDLC_02204 8.27e-187 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEKKCDLC_02205 4.14e-176 - - - I ko:K15313 - ko00000,ko01008 Belongs to the enoyl-CoA hydratase isomerase family
IEKKCDLC_02206 3.9e-306 - 2.3.3.10 - I ko:K01641,ko:K15311 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01008 synthase
IEKKCDLC_02207 4.87e-282 - 1.14.14.46 - C ko:K15468,ko:K16593 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
IEKKCDLC_02208 0.0 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IEKKCDLC_02209 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_02210 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_02211 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_02212 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_02213 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_02214 0.0 - - - Q ko:K13612,ko:K13613 - ko00000,ko01004,ko01008 Polyketide synthase of type I
IEKKCDLC_02215 2.78e-168 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
IEKKCDLC_02216 1.36e-314 - 6.1.3.1, 6.2.1.3, 6.2.1.34 - IQ ko:K00666,ko:K01897,ko:K12508,ko:K22319 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IEKKCDLC_02219 0.0 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
IEKKCDLC_02220 5.26e-123 nusG1 - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
IEKKCDLC_02221 4.95e-42 - - - S - - - GlpM protein
IEKKCDLC_02222 1.27e-247 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IEKKCDLC_02223 1.11e-189 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IEKKCDLC_02224 3.23e-219 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IEKKCDLC_02225 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IEKKCDLC_02226 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEKKCDLC_02227 1.35e-301 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEKKCDLC_02228 1.3e-34 yqzJ - - - - - - -
IEKKCDLC_02229 1.68e-190 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEKKCDLC_02230 1.06e-258 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
IEKKCDLC_02231 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IEKKCDLC_02232 7.7e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
IEKKCDLC_02234 2.61e-123 yqjB - - S - - - protein conserved in bacteria
IEKKCDLC_02235 1.6e-219 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
IEKKCDLC_02236 2.58e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IEKKCDLC_02237 1.04e-141 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
IEKKCDLC_02238 5.83e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IEKKCDLC_02239 2.04e-66 - - - L - - - transposase activity
IEKKCDLC_02240 1.23e-151 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
IEKKCDLC_02241 4.83e-99 yqiW - - S - - - Belongs to the UPF0403 family
IEKKCDLC_02242 4.08e-217 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IEKKCDLC_02243 2.08e-283 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IEKKCDLC_02244 1.7e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IEKKCDLC_02245 7.89e-222 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IEKKCDLC_02246 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IEKKCDLC_02247 6.96e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
IEKKCDLC_02248 6.41e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IEKKCDLC_02249 1.67e-195 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
IEKKCDLC_02250 0.0 bkdR - - KT - - - Transcriptional regulator
IEKKCDLC_02251 7.32e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
IEKKCDLC_02252 4e-205 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IEKKCDLC_02253 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
IEKKCDLC_02254 1.03e-262 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IEKKCDLC_02255 3.56e-260 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
IEKKCDLC_02256 4.16e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
IEKKCDLC_02257 1.08e-269 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
IEKKCDLC_02258 1.56e-174 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
IEKKCDLC_02259 1.39e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
IEKKCDLC_02261 3.25e-130 - - - P - - - Probably functions as a manganese efflux pump
IEKKCDLC_02262 6.93e-147 - - - K - - - Protein of unknown function (DUF1232)
IEKKCDLC_02264 2.77e-273 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IEKKCDLC_02267 4.3e-276 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEKKCDLC_02268 1.23e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IEKKCDLC_02269 3.6e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
IEKKCDLC_02270 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
IEKKCDLC_02271 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
IEKKCDLC_02272 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
IEKKCDLC_02273 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IEKKCDLC_02274 9.49e-206 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
IEKKCDLC_02275 2.67e-52 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEKKCDLC_02276 5.6e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEKKCDLC_02277 3.05e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IEKKCDLC_02278 2.2e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IEKKCDLC_02279 1.36e-87 yqhY - - S - - - protein conserved in bacteria
IEKKCDLC_02280 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IEKKCDLC_02281 2.32e-86 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IEKKCDLC_02282 2.74e-94 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
IEKKCDLC_02283 1.16e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
IEKKCDLC_02284 1.05e-130 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
IEKKCDLC_02285 5.23e-261 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
IEKKCDLC_02286 3.72e-55 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
IEKKCDLC_02287 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
IEKKCDLC_02288 1.4e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
IEKKCDLC_02289 2.99e-219 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
IEKKCDLC_02290 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
IEKKCDLC_02291 6.82e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEKKCDLC_02292 6.04e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
IEKKCDLC_02293 3.99e-118 yqhR - - S - - - Conserved membrane protein YqhR
IEKKCDLC_02294 2.01e-218 yqhQ - - S - - - Protein of unknown function (DUF1385)
IEKKCDLC_02295 7.65e-83 yqhP - - - - - - -
IEKKCDLC_02296 9.94e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
IEKKCDLC_02297 5.64e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IEKKCDLC_02298 1.58e-204 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IEKKCDLC_02299 3.18e-84 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
IEKKCDLC_02300 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IEKKCDLC_02301 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IEKKCDLC_02302 5.51e-263 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
IEKKCDLC_02303 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IEKKCDLC_02304 3.06e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
IEKKCDLC_02305 2.31e-32 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
IEKKCDLC_02306 2.75e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
IEKKCDLC_02307 1.82e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
IEKKCDLC_02308 1.89e-102 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
IEKKCDLC_02309 6.62e-156 yqxM - - - ko:K19433 - ko00000 -
IEKKCDLC_02310 5.66e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
IEKKCDLC_02311 2e-36 yqzE - - S - - - YqzE-like protein
IEKKCDLC_02312 4.9e-83 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
IEKKCDLC_02313 1.56e-85 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
IEKKCDLC_02314 6.31e-26 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
IEKKCDLC_02315 2.37e-95 - - - NU ko:K02246,ko:K08084 - ko00000,ko00002,ko02044 Tfp pilus assembly protein FimT
IEKKCDLC_02316 4.29e-64 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
IEKKCDLC_02317 7.69e-232 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
IEKKCDLC_02318 2.22e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IEKKCDLC_02319 6.43e-239 yqxL - - P - - - Mg2 transporter protein
IEKKCDLC_02320 6.5e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IEKKCDLC_02321 1.68e-189 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IEKKCDLC_02323 1.15e-86 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
IEKKCDLC_02324 4.19e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
IEKKCDLC_02325 3.45e-157 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
IEKKCDLC_02326 1.07e-28 yqgW - - S - - - Protein of unknown function (DUF2759)
IEKKCDLC_02327 2.99e-65 dglA - - S - - - Thiamine-binding protein
IEKKCDLC_02328 6.3e-255 yqgU - - - - - - -
IEKKCDLC_02329 5.28e-286 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
IEKKCDLC_02330 2.05e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
IEKKCDLC_02331 1.21e-274 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
IEKKCDLC_02332 5.38e-11 yqgO - - - - - - -
IEKKCDLC_02333 8.62e-126 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEKKCDLC_02334 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
IEKKCDLC_02335 3.42e-68 yqzD - - - - - - -
IEKKCDLC_02336 2.5e-99 yqzC - - S - - - Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEKKCDLC_02337 6.64e-188 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEKKCDLC_02338 1.75e-187 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEKKCDLC_02339 5.88e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
IEKKCDLC_02340 6.1e-204 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
IEKKCDLC_02341 2.24e-206 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
IEKKCDLC_02342 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
IEKKCDLC_02343 2.37e-289 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
IEKKCDLC_02344 4.22e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
IEKKCDLC_02345 4.77e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
IEKKCDLC_02346 1.08e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
IEKKCDLC_02347 3.57e-62 yqfZ - - M ko:K06417 - ko00000 LysM domain
IEKKCDLC_02348 3.97e-256 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IEKKCDLC_02349 3.34e-80 yqfX - - S - - - membrane
IEKKCDLC_02350 7.06e-143 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
IEKKCDLC_02351 9.16e-100 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
IEKKCDLC_02352 5.44e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IEKKCDLC_02353 8.63e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
IEKKCDLC_02354 1.21e-213 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IEKKCDLC_02355 6.06e-308 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IEKKCDLC_02356 3.93e-87 yqfQ - - S - - - YqfQ-like protein
IEKKCDLC_02357 8.66e-227 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IEKKCDLC_02358 3.1e-268 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEKKCDLC_02359 8.52e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
IEKKCDLC_02360 9.68e-83 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IEKKCDLC_02361 3.97e-255 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IEKKCDLC_02362 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IEKKCDLC_02363 1.36e-112 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
IEKKCDLC_02364 5.46e-192 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IEKKCDLC_02365 5.89e-145 ccpN - - K - - - CBS domain
IEKKCDLC_02366 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
IEKKCDLC_02367 5.19e-223 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
IEKKCDLC_02368 8.73e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
IEKKCDLC_02369 6e-24 - - - S - - - YqzL-like protein
IEKKCDLC_02370 1.42e-214 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEKKCDLC_02371 1.92e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IEKKCDLC_02372 5.28e-83 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
IEKKCDLC_02373 7.14e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IEKKCDLC_02374 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
IEKKCDLC_02375 2.47e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
IEKKCDLC_02376 1.84e-282 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
IEKKCDLC_02377 3.57e-61 yqfC - - S - - - sporulation protein YqfC
IEKKCDLC_02378 1.47e-84 yqfB - - - - - - -
IEKKCDLC_02379 4.48e-189 yqfA - - S - - - UPF0365 protein
IEKKCDLC_02380 5.44e-295 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
IEKKCDLC_02381 7.84e-91 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
IEKKCDLC_02382 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
IEKKCDLC_02383 5.59e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
IEKKCDLC_02384 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
IEKKCDLC_02385 2.91e-180 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IEKKCDLC_02386 3.8e-224 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
IEKKCDLC_02387 4.93e-266 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IEKKCDLC_02388 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
IEKKCDLC_02389 5.18e-110 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IEKKCDLC_02390 2.73e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IEKKCDLC_02391 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
IEKKCDLC_02392 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEKKCDLC_02393 2.1e-71 yqxA - - S - - - Protein of unknown function (DUF3679)
IEKKCDLC_02394 7.46e-279 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
IEKKCDLC_02395 4.16e-259 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IEKKCDLC_02396 1.91e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
IEKKCDLC_02397 2.13e-231 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
IEKKCDLC_02398 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
IEKKCDLC_02399 3.79e-136 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
IEKKCDLC_02400 5.06e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
IEKKCDLC_02401 6.61e-190 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IEKKCDLC_02402 8.39e-179 yqeM - - Q - - - Methyltransferase
IEKKCDLC_02403 4.65e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IEKKCDLC_02404 2.38e-133 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
IEKKCDLC_02405 2.89e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IEKKCDLC_02406 1.81e-60 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
IEKKCDLC_02407 2.32e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IEKKCDLC_02408 7.93e-272 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IEKKCDLC_02409 5.51e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
IEKKCDLC_02411 3.07e-179 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
IEKKCDLC_02412 1.34e-179 pdaC 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
IEKKCDLC_02413 8.36e-138 yqeD - - S - - - SNARE associated Golgi protein
IEKKCDLC_02414 6.18e-268 - - - EGP - - - Transmembrane secretion effector
IEKKCDLC_02415 1.67e-160 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IEKKCDLC_02416 2.74e-33 xkdS - - S - - - Protein of unknown function (DUF2634)
IEKKCDLC_02417 1.14e-140 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
IEKKCDLC_02418 3.94e-27 xkdR - - S - - - Protein of unknown function (DUF2577)
IEKKCDLC_02420 2.03e-173 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Reductase
IEKKCDLC_02421 2.72e-91 - - - K - - - MerR family transcriptional regulator
IEKKCDLC_02422 2.4e-20 xkdG - - S - - - Phage capsid family
IEKKCDLC_02423 3.89e-206 - - - S - - - Carbohydrate esterase, sialic acid-specific acetylesterase
IEKKCDLC_02424 9.84e-123 - - - K - - - Transcriptional regulator PadR-like family
IEKKCDLC_02425 1.84e-91 psiE - - S ko:K13256 - ko00000 Belongs to the PsiE family
IEKKCDLC_02426 3.79e-308 yrkQ - - T - - - Histidine kinase
IEKKCDLC_02427 7.69e-159 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
IEKKCDLC_02428 2.11e-273 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
IEKKCDLC_02429 4.24e-128 yrkN - - K - - - Acetyltransferase (GNAT) family
IEKKCDLC_02430 6.4e-129 yqaC - - F - - - adenylate kinase activity
IEKKCDLC_02431 5.25e-41 - - - K - - - acetyltransferase
IEKKCDLC_02432 7.59e-280 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_02433 2.48e-104 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
IEKKCDLC_02434 4.07e-122 - - - S - - - DinB family
IEKKCDLC_02435 4.46e-185 supH - - S - - - hydrolase
IEKKCDLC_02436 5.02e-188 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
IEKKCDLC_02437 1.18e-167 - - - K - - - Helix-turn-helix domain, rpiR family
IEKKCDLC_02438 5.48e-235 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IEKKCDLC_02439 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_02440 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
IEKKCDLC_02441 5.91e-234 romA - - S - - - Beta-lactamase superfamily domain
IEKKCDLC_02442 1.96e-108 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEKKCDLC_02443 7.57e-211 yybE - - K - - - Transcriptional regulator
IEKKCDLC_02444 3.77e-270 yybF1 - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_02445 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
IEKKCDLC_02446 3.92e-129 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
IEKKCDLC_02447 9.01e-121 yrhH - - Q - - - methyltransferase
IEKKCDLC_02448 2.37e-07 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
IEKKCDLC_02449 3.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
IEKKCDLC_02450 1.54e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
IEKKCDLC_02451 0.0 yrhE 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase, alpha subunit
IEKKCDLC_02452 4.76e-106 yrhD - - S - - - Protein of unknown function (DUF1641)
IEKKCDLC_02453 9.51e-47 yrhC - - S - - - YrhC-like protein
IEKKCDLC_02454 1.31e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
IEKKCDLC_02455 2.28e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
IEKKCDLC_02456 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEKKCDLC_02457 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
IEKKCDLC_02458 1.78e-38 yrzA - - S - - - Protein of unknown function (DUF2536)
IEKKCDLC_02459 3.56e-124 yrrS - - S - - - Protein of unknown function (DUF1510)
IEKKCDLC_02460 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
IEKKCDLC_02461 1.62e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEKKCDLC_02462 2.61e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
IEKKCDLC_02463 1.09e-311 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
IEKKCDLC_02464 2.2e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
IEKKCDLC_02465 2.22e-151 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
IEKKCDLC_02466 1.15e-258 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IEKKCDLC_02467 7.2e-61 yrzB - - S - - - Belongs to the UPF0473 family
IEKKCDLC_02468 2.72e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEKKCDLC_02469 1.29e-54 yrzL - - S - - - Belongs to the UPF0297 family
IEKKCDLC_02470 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IEKKCDLC_02471 6.63e-237 yrrI - - S - - - AI-2E family transporter
IEKKCDLC_02472 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IEKKCDLC_02473 7.39e-188 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
IEKKCDLC_02474 1.38e-140 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IEKKCDLC_02475 1.87e-139 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IEKKCDLC_02476 6.52e-13 - - - S - - - Protein of unknown function (DUF3918)
IEKKCDLC_02477 8.4e-42 yrzR - - - - - - -
IEKKCDLC_02478 2.92e-106 yrrD - - S - - - protein conserved in bacteria
IEKKCDLC_02479 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IEKKCDLC_02480 1.12e-23 yrrB - - S - - - COG0457 FOG TPR repeat
IEKKCDLC_02481 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IEKKCDLC_02482 1.48e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IEKKCDLC_02483 9.19e-84 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_02484 9.19e-304 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IEKKCDLC_02485 2.39e-178 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IEKKCDLC_02486 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IEKKCDLC_02487 6.05e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
IEKKCDLC_02490 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
IEKKCDLC_02491 4.95e-98 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IEKKCDLC_02492 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEKKCDLC_02493 5.1e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IEKKCDLC_02494 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
IEKKCDLC_02495 2.14e-60 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
IEKKCDLC_02496 3.1e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
IEKKCDLC_02497 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IEKKCDLC_02498 3.45e-68 yrzD - - S - - - Post-transcriptional regulator
IEKKCDLC_02499 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEKKCDLC_02500 6.8e-142 yrbG - - S - - - membrane
IEKKCDLC_02501 9.08e-81 yrzE - - S - - - Protein of unknown function (DUF3792)
IEKKCDLC_02502 1.03e-50 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
IEKKCDLC_02503 2.01e-293 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IEKKCDLC_02504 2.36e-245 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IEKKCDLC_02505 9.76e-29 yrzS - - S - - - Protein of unknown function (DUF2905)
IEKKCDLC_02506 6.17e-237 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IEKKCDLC_02507 8.13e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IEKKCDLC_02508 1.03e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
IEKKCDLC_02510 8.92e-61 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IEKKCDLC_02511 5.42e-251 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
IEKKCDLC_02512 6.48e-267 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IEKKCDLC_02513 1.83e-196 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
IEKKCDLC_02514 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
IEKKCDLC_02515 1.51e-280 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IEKKCDLC_02516 2.49e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
IEKKCDLC_02517 8.16e-206 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
IEKKCDLC_02518 5.94e-95 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
IEKKCDLC_02519 7.1e-311 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IEKKCDLC_02520 6.04e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
IEKKCDLC_02521 7.74e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
IEKKCDLC_02522 1.42e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
IEKKCDLC_02523 1.28e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
IEKKCDLC_02524 7.25e-206 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
IEKKCDLC_02525 4.65e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IEKKCDLC_02526 1.61e-183 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
IEKKCDLC_02527 6.85e-155 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IEKKCDLC_02528 1.76e-110 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
IEKKCDLC_02529 4.34e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
IEKKCDLC_02530 1.06e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
IEKKCDLC_02531 2.5e-164 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
IEKKCDLC_02532 2.36e-130 maf - - D ko:K06287 - ko00000 septum formation protein Maf
IEKKCDLC_02533 1.27e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
IEKKCDLC_02534 1.81e-171 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IEKKCDLC_02535 4.41e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
IEKKCDLC_02536 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IEKKCDLC_02537 3.09e-35 - - - - - - - -
IEKKCDLC_02538 1.55e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IEKKCDLC_02539 8.11e-290 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
IEKKCDLC_02540 1.62e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
IEKKCDLC_02541 9.83e-236 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
IEKKCDLC_02542 3.27e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
IEKKCDLC_02543 4.44e-224 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IEKKCDLC_02544 1.88e-186 hemX - - O ko:K02497 - ko00000 cytochrome C
IEKKCDLC_02545 4.36e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IEKKCDLC_02546 3.93e-114 ysxD - - - - - - -
IEKKCDLC_02547 1.79e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
IEKKCDLC_02548 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IEKKCDLC_02549 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
IEKKCDLC_02550 3.83e-295 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IEKKCDLC_02551 2.18e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IEKKCDLC_02552 1.92e-240 ysoA - - H - - - Tetratricopeptide repeat
IEKKCDLC_02553 3.77e-150 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IEKKCDLC_02554 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IEKKCDLC_02555 2.9e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IEKKCDLC_02556 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IEKKCDLC_02557 2.75e-244 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IEKKCDLC_02558 1.45e-109 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IEKKCDLC_02559 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
IEKKCDLC_02562 7e-55 res - - L - - - Resolvase, N terminal domain
IEKKCDLC_02563 9.82e-16 res - - L - - - Resolvase, N terminal domain
IEKKCDLC_02564 1.67e-101 hsdS 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 COG0732 Restriction endonuclease S subunits
IEKKCDLC_02565 2.45e-315 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
IEKKCDLC_02566 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
IEKKCDLC_02570 2.85e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
IEKKCDLC_02571 3.2e-131 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEKKCDLC_02572 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IEKKCDLC_02573 3.67e-254 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
IEKKCDLC_02574 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
IEKKCDLC_02575 3.77e-97 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
IEKKCDLC_02576 6.32e-42 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_02577 2.19e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
IEKKCDLC_02578 4.34e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IEKKCDLC_02579 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
IEKKCDLC_02580 2.73e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
IEKKCDLC_02581 2.45e-103 yslB - - S - - - Protein of unknown function (DUF2507)
IEKKCDLC_02582 1.01e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
IEKKCDLC_02583 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IEKKCDLC_02584 1.6e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
IEKKCDLC_02585 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
IEKKCDLC_02586 3.02e-228 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
IEKKCDLC_02587 8.64e-178 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
IEKKCDLC_02588 1.01e-177 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
IEKKCDLC_02589 6.22e-134 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_02590 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IEKKCDLC_02591 3.03e-157 ywbB - - S - - - Protein of unknown function (DUF2711)
IEKKCDLC_02592 3.09e-88 yshE - - S ko:K08989 - ko00000 membrane
IEKKCDLC_02593 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IEKKCDLC_02594 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
IEKKCDLC_02595 2.87e-107 yshB - - S - - - membrane protein, required for colicin V production
IEKKCDLC_02596 1.47e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IEKKCDLC_02597 1.53e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEKKCDLC_02598 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEKKCDLC_02599 2.19e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IEKKCDLC_02600 4.63e-173 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEKKCDLC_02601 1.07e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
IEKKCDLC_02602 7.21e-261 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
IEKKCDLC_02603 0.0 - 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD binding domain
IEKKCDLC_02604 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
IEKKCDLC_02605 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
IEKKCDLC_02606 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
IEKKCDLC_02607 6.84e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
IEKKCDLC_02608 3.6e-214 araP - - P ko:K10189,ko:K10241,ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PFAM binding-protein-dependent transport systems inner membrane component
IEKKCDLC_02609 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
IEKKCDLC_02610 3.88e-284 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IEKKCDLC_02611 3.06e-181 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
IEKKCDLC_02612 3.43e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IEKKCDLC_02613 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
IEKKCDLC_02614 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
IEKKCDLC_02615 4.03e-240 abnA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IEKKCDLC_02616 1.85e-263 ysdC - - G - - - COG1363 Cellulase M and related proteins
IEKKCDLC_02617 9.71e-90 ysdB - - S - - - Sigma-w pathway protein YsdB
IEKKCDLC_02618 7.74e-56 ysdA - - S - - - Membrane
IEKKCDLC_02619 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEKKCDLC_02620 1.95e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
IEKKCDLC_02621 1.79e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IEKKCDLC_02622 1.26e-146 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IEKKCDLC_02623 7.89e-69 - - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 effector of murein hydrolase LrgA
IEKKCDLC_02624 3e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
IEKKCDLC_02625 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_02626 7.21e-194 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
IEKKCDLC_02627 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEKKCDLC_02628 1.99e-197 ytxC - - S - - - YtxC-like family
IEKKCDLC_02629 7.7e-141 ytxB - - S - - - SNARE associated Golgi protein
IEKKCDLC_02630 1.42e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
IEKKCDLC_02631 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
IEKKCDLC_02632 5.95e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IEKKCDLC_02633 1.82e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IEKKCDLC_02634 1.8e-248 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEKKCDLC_02635 1.69e-89 ytcD - - K - - - Transcriptional regulator
IEKKCDLC_02636 3.96e-259 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
IEKKCDLC_02637 1.59e-205 ytbE - - S - - - reductase
IEKKCDLC_02638 2.41e-127 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEKKCDLC_02639 5.73e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
IEKKCDLC_02640 9.87e-203 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IEKKCDLC_02641 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEKKCDLC_02642 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
IEKKCDLC_02643 4.82e-166 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_02644 3.62e-218 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
IEKKCDLC_02645 1.32e-308 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
IEKKCDLC_02646 2.02e-268 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
IEKKCDLC_02647 5.5e-83 yjdF3 - - S - - - Protein of unknown function (DUF2992)
IEKKCDLC_02648 2.3e-95 ytwI - - S - - - membrane
IEKKCDLC_02649 4.73e-246 ytvI - - S - - - sporulation integral membrane protein YtvI
IEKKCDLC_02650 4.86e-84 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
IEKKCDLC_02651 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
IEKKCDLC_02652 3.98e-230 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IEKKCDLC_02653 3.83e-231 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IEKKCDLC_02654 3.59e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IEKKCDLC_02655 4.93e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IEKKCDLC_02656 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
IEKKCDLC_02657 4.94e-75 ytrH - - S - - - Sporulation protein YtrH
IEKKCDLC_02658 1.53e-113 ytrI - - - - - - -
IEKKCDLC_02659 1e-31 - - - - - - - -
IEKKCDLC_02660 3.04e-231 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
IEKKCDLC_02661 3.05e-63 ytpI - - S - - - YtpI-like protein
IEKKCDLC_02662 6.77e-305 ytoI - - K - - - transcriptional regulator containing CBS domains
IEKKCDLC_02663 4.86e-165 ytkL - - S - - - Belongs to the UPF0173 family
IEKKCDLC_02664 8.38e-184 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_02666 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
IEKKCDLC_02667 3.03e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
IEKKCDLC_02668 4.03e-115 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
IEKKCDLC_02669 2.33e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEKKCDLC_02670 3.18e-236 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
IEKKCDLC_02671 1.36e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IEKKCDLC_02672 4.77e-100 ytfJ - - S - - - Sporulation protein YtfJ
IEKKCDLC_02673 3.66e-156 ytfI - - S - - - Protein of unknown function (DUF2953)
IEKKCDLC_02674 2.77e-114 yteJ - - S - - - RDD family
IEKKCDLC_02675 6.39e-235 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
IEKKCDLC_02676 2.32e-196 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEKKCDLC_02677 0.0 ytcJ - - S - - - amidohydrolase
IEKKCDLC_02678 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IEKKCDLC_02679 2.05e-42 sspB - - S ko:K06418,ko:K06419 - ko00000 spore protein
IEKKCDLC_02680 6e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEKKCDLC_02681 6.74e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
IEKKCDLC_02682 1.96e-308 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
IEKKCDLC_02683 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IEKKCDLC_02684 1.46e-196 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IEKKCDLC_02685 6.92e-141 yttP - - K - - - Transcriptional regulator
IEKKCDLC_02686 5.2e-113 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
IEKKCDLC_02687 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
IEKKCDLC_02688 5.75e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IEKKCDLC_02689 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IEKKCDLC_02690 7.39e-132 yokH - - G - - - SMI1 / KNR4 family
IEKKCDLC_02691 7.52e-283 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEKKCDLC_02693 1.65e-118 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
IEKKCDLC_02695 2.14e-179 - - - E - - - GDSL-like Lipase/Acylhydrolase family
IEKKCDLC_02696 1.74e-193 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IEKKCDLC_02697 2.22e-190 - - - K - - - Transcriptional regulator
IEKKCDLC_02698 5.77e-160 ygaZ - - E - - - AzlC protein
IEKKCDLC_02699 2.07e-62 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
IEKKCDLC_02700 5.98e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEKKCDLC_02701 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IEKKCDLC_02702 2.84e-155 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IEKKCDLC_02703 7.2e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
IEKKCDLC_02704 1e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
IEKKCDLC_02705 6.07e-155 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
IEKKCDLC_02706 5.2e-186 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
IEKKCDLC_02707 4.86e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
IEKKCDLC_02708 1.54e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IEKKCDLC_02709 8.39e-58 ytxJ - - O - - - Protein of unknown function (DUF2847)
IEKKCDLC_02710 1.83e-30 ytxH - - S - - - COG4980 Gas vesicle protein
IEKKCDLC_02711 5.38e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEKKCDLC_02712 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
IEKKCDLC_02713 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
IEKKCDLC_02714 2.43e-138 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEKKCDLC_02715 1.69e-190 ytpQ - - S - - - Belongs to the UPF0354 family
IEKKCDLC_02716 1.84e-74 ytpP - - CO - - - Thioredoxin
IEKKCDLC_02717 1.42e-102 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
IEKKCDLC_02718 4.33e-260 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
IEKKCDLC_02719 9.96e-69 ytzB - - S - - - small secreted protein
IEKKCDLC_02720 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
IEKKCDLC_02721 1.94e-211 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
IEKKCDLC_02722 6.43e-160 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IEKKCDLC_02723 3.88e-60 ytzH - - S - - - YtzH-like protein
IEKKCDLC_02724 2.93e-199 ytmP - - M - - - Phosphotransferase
IEKKCDLC_02725 8.33e-227 ytlR - - I - - - Diacylglycerol kinase catalytic domain
IEKKCDLC_02726 6e-216 ytlQ - - - - - - -
IEKKCDLC_02727 1.1e-132 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IEKKCDLC_02728 4.79e-222 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
IEKKCDLC_02729 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
IEKKCDLC_02730 2.99e-290 pbuO - - S ko:K06901 - ko00000,ko02000 permease
IEKKCDLC_02731 1.5e-277 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
IEKKCDLC_02732 2.69e-165 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IEKKCDLC_02733 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
IEKKCDLC_02734 8.68e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
IEKKCDLC_02735 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEKKCDLC_02736 3.73e-299 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
IEKKCDLC_02737 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
IEKKCDLC_02738 2.14e-36 yteV - - S - - - Sporulation protein Cse60
IEKKCDLC_02739 1.58e-238 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_02740 6.83e-312 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
IEKKCDLC_02741 4.4e-215 - - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IEKKCDLC_02742 4.1e-184 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IEKKCDLC_02743 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
IEKKCDLC_02744 5.91e-112 - - - M - - - Acetyltransferase (GNAT) domain
IEKKCDLC_02745 6.05e-69 ytwF - - P - - - Sulfurtransferase
IEKKCDLC_02746 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
IEKKCDLC_02747 7.19e-69 ytvB - - S - - - Protein of unknown function (DUF4257)
IEKKCDLC_02748 1.45e-175 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IEKKCDLC_02749 1.66e-269 yttB - - EGP - - - Major facilitator superfamily
IEKKCDLC_02750 1.79e-158 ywaF - - S - - - Integral membrane protein
IEKKCDLC_02751 0.0 bceB - - V ko:K02004,ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
IEKKCDLC_02752 6.58e-174 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_02753 2.78e-218 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
IEKKCDLC_02754 2.6e-166 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_02755 1.93e-287 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
IEKKCDLC_02756 2.12e-161 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_02757 9e-210 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
IEKKCDLC_02758 2.8e-230 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IEKKCDLC_02759 1.66e-222 ytrC - - S ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IEKKCDLC_02760 1.46e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_02761 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
IEKKCDLC_02763 7.09e-53 ytzC - - S - - - Protein of unknown function (DUF2524)
IEKKCDLC_02764 2.79e-250 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IEKKCDLC_02765 0.0 - - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_02766 5.76e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
IEKKCDLC_02767 1.08e-137 ytqB - - J - - - Putative rRNA methylase
IEKKCDLC_02769 2.47e-183 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
IEKKCDLC_02770 2.35e-270 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
IEKKCDLC_02771 6.95e-194 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
IEKKCDLC_02772 4.06e-84 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IEKKCDLC_02773 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IEKKCDLC_02774 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
IEKKCDLC_02775 7.88e-287 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IEKKCDLC_02776 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IEKKCDLC_02777 2.85e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
IEKKCDLC_02778 1.57e-189 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IEKKCDLC_02779 5.29e-238 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IEKKCDLC_02780 6.12e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IEKKCDLC_02781 2.16e-173 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IEKKCDLC_02782 4.13e-114 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
IEKKCDLC_02783 1.23e-79 ytkC - - S - - - Bacteriophage holin family
IEKKCDLC_02784 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IEKKCDLC_02786 1.04e-99 ytkA - - S - - - YtkA-like
IEKKCDLC_02787 7.16e-114 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IEKKCDLC_02788 6.93e-53 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
IEKKCDLC_02789 9.31e-137 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IEKKCDLC_02790 8.35e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
IEKKCDLC_02791 1.82e-312 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IEKKCDLC_02792 4.3e-234 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IEKKCDLC_02793 1.92e-34 - - - S - - - Domain of Unknown Function (DUF1540)
IEKKCDLC_02794 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IEKKCDLC_02795 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IEKKCDLC_02796 2.16e-199 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IEKKCDLC_02797 4.18e-198 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IEKKCDLC_02798 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IEKKCDLC_02799 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IEKKCDLC_02800 3.03e-169 yteA - - T - - - COG1734 DnaK suppressor protein
IEKKCDLC_02801 9.03e-103 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
IEKKCDLC_02823 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
IEKKCDLC_02824 5.96e-126 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
IEKKCDLC_02825 3.58e-276 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
IEKKCDLC_02826 1.96e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
IEKKCDLC_02827 1.08e-106 yuaE - - S - - - DinB superfamily
IEKKCDLC_02828 6.79e-141 - - - S - - - MOSC domain
IEKKCDLC_02829 5.82e-289 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
IEKKCDLC_02830 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IEKKCDLC_02831 2.89e-124 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
IEKKCDLC_02832 2.89e-122 yuaB - - - - - - -
IEKKCDLC_02833 5.04e-155 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
IEKKCDLC_02834 1.82e-191 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IEKKCDLC_02835 2.16e-284 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IEKKCDLC_02836 6.7e-160 - - - G - - - Cupin
IEKKCDLC_02837 2.63e-69 yjcN - - - - - - -
IEKKCDLC_02839 3.79e-186 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IEKKCDLC_02840 9.96e-251 yubA - - S - - - transporter activity
IEKKCDLC_02841 1.35e-237 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IEKKCDLC_02842 6.95e-127 yraA 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 DJ-1/PfpI family
IEKKCDLC_02843 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IEKKCDLC_02844 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IEKKCDLC_02845 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IEKKCDLC_02846 1.32e-315 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
IEKKCDLC_02847 9.03e-179 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IEKKCDLC_02848 1.61e-55 - - - - - - - -
IEKKCDLC_02849 6e-244 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IEKKCDLC_02850 6.13e-100 yugU - - S - - - Uncharacterised protein family UPF0047
IEKKCDLC_02851 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
IEKKCDLC_02852 1.63e-296 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
IEKKCDLC_02853 1.67e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
IEKKCDLC_02854 4.35e-23 - - - - - - - -
IEKKCDLC_02855 2.44e-35 mstX - - S - - - Membrane-integrating protein Mistic
IEKKCDLC_02856 4.84e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
IEKKCDLC_02857 8.53e-95 yugN - - S - - - YugN-like family
IEKKCDLC_02859 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
IEKKCDLC_02860 1.95e-133 - - - S ko:K19784 - ko00000 NADPH-dependent FMN reductase
IEKKCDLC_02861 4.34e-152 ycaC - - Q - - - Isochorismatase family
IEKKCDLC_02862 1.86e-289 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
IEKKCDLC_02863 1.65e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
IEKKCDLC_02864 3.14e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
IEKKCDLC_02865 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
IEKKCDLC_02866 1.38e-265 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
IEKKCDLC_02867 3.75e-109 alaR - - K - - - Transcriptional regulator
IEKKCDLC_02868 4.03e-200 yugF - - I - - - Hydrolase
IEKKCDLC_02869 1.22e-54 yugE - - S - - - Domain of unknown function (DUF1871)
IEKKCDLC_02870 1.35e-285 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IEKKCDLC_02871 1.81e-292 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_02872 6.88e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
IEKKCDLC_02873 3.22e-152 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
IEKKCDLC_02874 2.48e-245 yuxJ - - EGP - - - Major facilitator superfamily
IEKKCDLC_02875 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
IEKKCDLC_02876 2.62e-95 yuxK - - S - - - protein conserved in bacteria
IEKKCDLC_02877 1.6e-101 yufK - - S - - - Family of unknown function (DUF5366)
IEKKCDLC_02878 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
IEKKCDLC_02879 5.63e-163 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
IEKKCDLC_02880 4.98e-250 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
IEKKCDLC_02881 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_02882 2.72e-238 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IEKKCDLC_02883 4.39e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IEKKCDLC_02885 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IEKKCDLC_02886 5.39e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEKKCDLC_02887 1.47e-67 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEKKCDLC_02888 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEKKCDLC_02889 1.23e-101 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEKKCDLC_02890 1.91e-52 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IEKKCDLC_02891 4.2e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
IEKKCDLC_02892 3.42e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
IEKKCDLC_02893 8.07e-148 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEKKCDLC_02894 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_02896 1.7e-111 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Polyprenyl synthetase
IEKKCDLC_02897 2.66e-11 - - - S - - - DegQ (SacQ) family
IEKKCDLC_02898 6.01e-67 yuzC - - - - - - -
IEKKCDLC_02899 6.86e-296 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
IEKKCDLC_02900 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEKKCDLC_02901 8.02e-135 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
IEKKCDLC_02902 7.94e-90 yueI - - S - - - Protein of unknown function (DUF1694)
IEKKCDLC_02903 5.46e-51 yueH - - S - - - YueH-like protein
IEKKCDLC_02904 6.33e-46 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
IEKKCDLC_02905 1.88e-238 yueF - - S - - - transporter activity
IEKKCDLC_02906 1.98e-31 - - - S - - - Protein of unknown function (DUF2642)
IEKKCDLC_02907 1.57e-124 yueE - - S ko:K06950 - ko00000 phosphohydrolase
IEKKCDLC_02908 1.32e-165 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_02909 8.01e-102 yueC - - S - - - Family of unknown function (DUF5383)
IEKKCDLC_02910 0.0 yueB - - S - - - type VII secretion protein EsaA
IEKKCDLC_02911 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IEKKCDLC_02912 4.59e-275 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
IEKKCDLC_02913 5.28e-53 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
IEKKCDLC_02914 1.94e-60 yukE - - S - - - Belongs to the WXG100 family
IEKKCDLC_02915 5.19e-292 yukF - - QT - - - Transcriptional regulator
IEKKCDLC_02916 5.7e-261 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
IEKKCDLC_02917 1.77e-170 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
IEKKCDLC_02918 1.91e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
IEKKCDLC_02919 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_02920 5.59e-220 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
IEKKCDLC_02921 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
IEKKCDLC_02922 4.55e-285 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
IEKKCDLC_02923 7.08e-171 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_02924 5.13e-211 eSD - - S ko:K07017 - ko00000 Putative esterase
IEKKCDLC_02925 1.13e-155 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
IEKKCDLC_02926 3.73e-131 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
IEKKCDLC_02927 2.01e-276 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
IEKKCDLC_02928 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IEKKCDLC_02929 1.01e-100 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
IEKKCDLC_02930 4.18e-154 yuiC - - S - - - protein conserved in bacteria
IEKKCDLC_02931 8.54e-46 yuiB - - S - - - Putative membrane protein
IEKKCDLC_02932 2.69e-297 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IEKKCDLC_02933 1.03e-238 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
IEKKCDLC_02935 1.15e-237 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEKKCDLC_02936 5.68e-40 - - - - - - - -
IEKKCDLC_02937 1.19e-92 - - - CP - - - Membrane
IEKKCDLC_02938 1.18e-159 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
IEKKCDLC_02940 5.3e-44 - - - S - - - Bacteriocin class IId cyclical uberolysin-like
IEKKCDLC_02942 1.76e-123 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
IEKKCDLC_02943 1.67e-173 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_02944 1.38e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
IEKKCDLC_02945 2.25e-207 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IEKKCDLC_02946 6.06e-273 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEKKCDLC_02947 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
IEKKCDLC_02948 1.71e-265 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
IEKKCDLC_02949 4.5e-71 yuzD - - S - - - protein conserved in bacteria
IEKKCDLC_02950 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
IEKKCDLC_02951 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
IEKKCDLC_02952 4.76e-217 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IEKKCDLC_02953 2.8e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IEKKCDLC_02954 1.43e-308 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
IEKKCDLC_02955 6.3e-250 yutH - - S - - - Spore coat protein
IEKKCDLC_02956 1.5e-109 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
IEKKCDLC_02957 4.31e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IEKKCDLC_02958 1.55e-95 yutE - - S - - - Protein of unknown function DUF86
IEKKCDLC_02959 3.71e-62 yutD - - S - - - protein conserved in bacteria
IEKKCDLC_02960 3.92e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IEKKCDLC_02961 1.66e-250 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
IEKKCDLC_02962 3.21e-166 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
IEKKCDLC_02963 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
IEKKCDLC_02964 3.01e-186 yunE - - S ko:K07090 - ko00000 membrane transporter protein
IEKKCDLC_02965 2.02e-214 yunF - - S - - - Protein of unknown function DUF72
IEKKCDLC_02966 6.14e-80 - - - S - - - phosphoglycolate phosphatase activity
IEKKCDLC_02967 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IEKKCDLC_02968 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
IEKKCDLC_02969 8.78e-18 yqbD - - L - - - Putative phage serine protease XkdF
IEKKCDLC_02971 9.82e-20 - - - - - - - -
IEKKCDLC_02974 5.21e-275 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_02975 9.87e-301 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IEKKCDLC_02976 4.87e-299 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IEKKCDLC_02977 4.09e-217 bsn - - L - - - Ribonuclease
IEKKCDLC_02978 1.3e-262 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_02979 3.41e-172 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
IEKKCDLC_02980 4.37e-205 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
IEKKCDLC_02981 3.6e-209 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
IEKKCDLC_02982 1.06e-202 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IEKKCDLC_02983 2.12e-312 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
IEKKCDLC_02984 9.5e-238 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IEKKCDLC_02985 6.7e-212 - - - K - - - helix_turn_helix, mercury resistance
IEKKCDLC_02988 5.74e-86 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
IEKKCDLC_02989 8.71e-258 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
IEKKCDLC_02990 8.53e-163 - - - Q - - - ubiE/COQ5 methyltransferase family
IEKKCDLC_02991 4.34e-104 yncE - - S - - - Protein of unknown function (DUF2691)
IEKKCDLC_02992 5.94e-200 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IEKKCDLC_02993 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
IEKKCDLC_02994 8.89e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
IEKKCDLC_02995 2.31e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEKKCDLC_02996 8.67e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
IEKKCDLC_02997 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IEKKCDLC_02998 8.85e-85 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IEKKCDLC_02999 1.82e-186 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
IEKKCDLC_03000 1.46e-138 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
IEKKCDLC_03001 3.71e-237 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEKKCDLC_03002 1.29e-76 yusD - - S - - - SCP-2 sterol transfer family
IEKKCDLC_03003 1.64e-72 yusE - - CO - - - Thioredoxin
IEKKCDLC_03004 1.08e-82 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
IEKKCDLC_03005 5.16e-54 yusG - - S - - - Protein of unknown function (DUF2553)
IEKKCDLC_03006 2.41e-84 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IEKKCDLC_03007 7.13e-84 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
IEKKCDLC_03008 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
IEKKCDLC_03009 9.03e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
IEKKCDLC_03010 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
IEKKCDLC_03011 3.09e-214 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
IEKKCDLC_03012 1.48e-263 yusP - - P - - - Major facilitator superfamily
IEKKCDLC_03013 3.2e-58 - - - - - - - -
IEKKCDLC_03014 1.82e-71 yusN - - M - - - Coat F domain
IEKKCDLC_03015 9.65e-92 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
IEKKCDLC_03016 0.0 yusP - - P - - - Major facilitator superfamily
IEKKCDLC_03017 1.69e-86 yusQ - - S - - - Tautomerase enzyme
IEKKCDLC_03018 1.27e-169 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_03019 2.44e-206 yusT - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
IEKKCDLC_03020 1.52e-206 - - - K - - - Transcriptional regulator
IEKKCDLC_03021 1.24e-177 - 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
IEKKCDLC_03022 5.96e-241 apbA 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IEKKCDLC_03023 2.15e-52 yusU - - S - - - Protein of unknown function (DUF2573)
IEKKCDLC_03024 9.06e-193 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IEKKCDLC_03025 7.61e-60 - - - S - - - YusW-like protein
IEKKCDLC_03026 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
IEKKCDLC_03027 5.04e-195 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_03028 4.12e-103 dps2 - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
IEKKCDLC_03029 2.7e-299 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEKKCDLC_03030 3.17e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_03031 0.0 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_03032 4.63e-33 - - - - - - - -
IEKKCDLC_03033 3.11e-201 yuxN - - K - - - Transcriptional regulator
IEKKCDLC_03034 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IEKKCDLC_03035 1.83e-33 - - - S - - - Protein of unknown function (DUF3970)
IEKKCDLC_03036 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IEKKCDLC_03037 2.16e-244 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IEKKCDLC_03038 2.74e-265 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
IEKKCDLC_03039 1.02e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEKKCDLC_03040 9.98e-247 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_03041 8.92e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
IEKKCDLC_03042 9.24e-189 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
IEKKCDLC_03043 3.96e-133 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IEKKCDLC_03044 1.62e-68 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
IEKKCDLC_03045 5.58e-289 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_03046 3.1e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
IEKKCDLC_03047 4.22e-286 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IEKKCDLC_03048 1.96e-231 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_03049 3.33e-215 yvrC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
IEKKCDLC_03050 4.1e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_03051 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
IEKKCDLC_03052 0.0 yvrG - - T - - - Histidine kinase
IEKKCDLC_03053 2.7e-172 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_03054 1.67e-50 - - - - - - - -
IEKKCDLC_03055 3.23e-134 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
IEKKCDLC_03056 3.78e-21 - - - S - - - YvrJ protein family
IEKKCDLC_03057 3.11e-295 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
IEKKCDLC_03058 1.97e-87 yvrL - - S - - - Regulatory protein YrvL
IEKKCDLC_03059 1.97e-188 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
IEKKCDLC_03060 2.76e-225 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_03061 1.56e-236 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_03062 1.28e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
IEKKCDLC_03063 3.57e-159 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IEKKCDLC_03064 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
IEKKCDLC_03065 1.29e-20 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
IEKKCDLC_03066 1.01e-110 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
IEKKCDLC_03067 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
IEKKCDLC_03068 1.65e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
IEKKCDLC_03069 1.95e-178 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
IEKKCDLC_03070 1.29e-121 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
IEKKCDLC_03071 2.05e-146 yfiK - - K - - - Regulator
IEKKCDLC_03072 1.49e-253 - - - T - - - Histidine kinase
IEKKCDLC_03073 1.42e-219 sagG - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
IEKKCDLC_03074 8.58e-250 sagH - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
IEKKCDLC_03075 4.17e-261 sagI - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
IEKKCDLC_03076 1.77e-200 yvgN - - S - - - reductase
IEKKCDLC_03077 1.38e-113 yvgO - - - - - - -
IEKKCDLC_03078 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
IEKKCDLC_03079 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IEKKCDLC_03080 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IEKKCDLC_03081 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
IEKKCDLC_03082 6.36e-130 yvgT - - S - - - membrane
IEKKCDLC_03083 1.57e-189 - - - S - - - Metallo-peptidase family M12
IEKKCDLC_03084 1.83e-96 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
IEKKCDLC_03085 3.05e-136 bdbD - - O - - - Thioredoxin
IEKKCDLC_03086 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
IEKKCDLC_03087 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
IEKKCDLC_03088 3.24e-40 - - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Heavy-metal-associated domain
IEKKCDLC_03089 8.06e-64 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
IEKKCDLC_03090 1.31e-244 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
IEKKCDLC_03091 1.71e-152 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IEKKCDLC_03092 4.21e-207 - - - K - - - Helix-turn-helix XRE-family like proteins
IEKKCDLC_03093 6.18e-282 - - - EGP - - - Major Facilitator Superfamily
IEKKCDLC_03094 2.61e-91 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IEKKCDLC_03095 1.19e-186 - - - S ko:K07045 - ko00000 Amidohydrolase
IEKKCDLC_03096 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEKKCDLC_03097 4.82e-60 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
IEKKCDLC_03098 8.42e-234 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEKKCDLC_03099 3.67e-180 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
IEKKCDLC_03100 5.8e-156 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IEKKCDLC_03101 7.29e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
IEKKCDLC_03102 3.69e-190 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IEKKCDLC_03103 3.41e-167 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
IEKKCDLC_03104 3.16e-130 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
IEKKCDLC_03105 9.38e-205 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
IEKKCDLC_03106 3.94e-180 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
IEKKCDLC_03107 7.35e-59 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
IEKKCDLC_03109 4.85e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IEKKCDLC_03110 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IEKKCDLC_03111 1.7e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
IEKKCDLC_03112 4.58e-36 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
IEKKCDLC_03113 1.64e-47 yvzC - - K - - - transcriptional
IEKKCDLC_03114 9.53e-93 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
IEKKCDLC_03115 3.52e-96 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
IEKKCDLC_03116 8.55e-68 yvaP - - K - - - transcriptional
IEKKCDLC_03117 1.86e-202 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
IEKKCDLC_03118 4.5e-132 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
IEKKCDLC_03119 7.69e-109 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IEKKCDLC_03120 5.83e-111 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IEKKCDLC_03121 4.78e-129 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_03126 1.9e-118 - - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 PFAM Lanthionine synthetase
IEKKCDLC_03127 1.96e-191 - - - V ko:K06147,ko:K06148,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
IEKKCDLC_03128 1.67e-233 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
IEKKCDLC_03129 7.38e-133 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IEKKCDLC_03130 1.27e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IEKKCDLC_03131 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IEKKCDLC_03132 5.78e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IEKKCDLC_03133 3.42e-124 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IEKKCDLC_03134 6.21e-141 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IEKKCDLC_03135 4.43e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IEKKCDLC_03136 1.61e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
IEKKCDLC_03137 5.16e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IEKKCDLC_03138 4.11e-129 - - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
IEKKCDLC_03139 3.8e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
IEKKCDLC_03140 2.66e-157 yvbI - - M - - - Membrane
IEKKCDLC_03141 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
IEKKCDLC_03142 1.11e-106 yvbK - - K - - - acetyltransferase
IEKKCDLC_03143 2.68e-270 - - - EGP - - - Major facilitator Superfamily
IEKKCDLC_03144 2.3e-227 - - - - - - - -
IEKKCDLC_03145 6.37e-162 - - - S - - - GlcNAc-PI de-N-acetylase
IEKKCDLC_03146 2.89e-185 - - - C - - - WbqC-like protein family
IEKKCDLC_03147 1.86e-190 - - - M - - - Protein involved in cellulose biosynthesis
IEKKCDLC_03148 2.15e-300 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IEKKCDLC_03149 2.99e-220 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
IEKKCDLC_03150 4.83e-278 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IEKKCDLC_03151 0.0 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEKKCDLC_03152 1.78e-305 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
IEKKCDLC_03153 9.69e-310 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEKKCDLC_03154 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
IEKKCDLC_03155 2.58e-177 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IEKKCDLC_03156 6.6e-276 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
IEKKCDLC_03157 2.83e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEKKCDLC_03158 2.95e-240 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IEKKCDLC_03160 0.0 araE - - U ko:K02100,ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IEKKCDLC_03161 9.49e-262 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
IEKKCDLC_03163 1.71e-241 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEKKCDLC_03164 3.72e-161 yvbU - - K - - - Transcriptional regulator
IEKKCDLC_03165 5.22e-203 yvbV - - EG - - - EamA-like transporter family
IEKKCDLC_03166 4.71e-275 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
IEKKCDLC_03167 0.0 - - - - - - - -
IEKKCDLC_03168 3.55e-231 yhjM - - K - - - Transcriptional regulator
IEKKCDLC_03169 5.19e-148 - - - S ko:K07149 - ko00000 Membrane
IEKKCDLC_03170 2.09e-213 - 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IEKKCDLC_03171 1.56e-194 gntR - - K - - - RpiR family transcriptional regulator
IEKKCDLC_03172 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
IEKKCDLC_03173 1.37e-290 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
IEKKCDLC_03174 2.91e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IEKKCDLC_03175 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IEKKCDLC_03176 6.14e-173 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IEKKCDLC_03177 2.62e-283 - - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEKKCDLC_03178 3.1e-156 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
IEKKCDLC_03179 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
IEKKCDLC_03180 1.32e-308 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IEKKCDLC_03181 4.01e-44 yvfG - - S - - - YvfG protein
IEKKCDLC_03182 8.14e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
IEKKCDLC_03183 3.31e-283 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
IEKKCDLC_03184 5.73e-79 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IEKKCDLC_03185 1.92e-140 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IEKKCDLC_03186 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEKKCDLC_03187 6.3e-251 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
IEKKCDLC_03188 2.23e-258 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
IEKKCDLC_03189 3.24e-249 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IEKKCDLC_03190 4.89e-262 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
IEKKCDLC_03191 2.88e-271 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
IEKKCDLC_03192 2.74e-206 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
IEKKCDLC_03193 1.01e-276 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
IEKKCDLC_03194 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
IEKKCDLC_03195 7.67e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IEKKCDLC_03196 4.08e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
IEKKCDLC_03197 6.96e-100 - - - K ko:K19417 - ko00000,ko03000 transcriptional
IEKKCDLC_03198 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
IEKKCDLC_03199 3.85e-125 ywjB - - H - - - RibD C-terminal domain
IEKKCDLC_03200 2.51e-144 yyaS - - S ko:K07149 - ko00000 Membrane
IEKKCDLC_03201 5.46e-119 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEKKCDLC_03202 2.47e-121 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
IEKKCDLC_03203 1.16e-17 - - - S - - - Protein of unknown function (DUF1433)
IEKKCDLC_03204 2.64e-54 - - - S - - - Protein of unknown function (DUF1433)
IEKKCDLC_03205 2.94e-302 - - - I - - - Pfam Lipase (class 3)
IEKKCDLC_03206 1.94e-47 - - - - - - - -
IEKKCDLC_03208 0.0 cscA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IEKKCDLC_03209 3.19e-282 rafB - - P ko:K02532 - ko00000,ko02000 LacY proton/sugar symporter
IEKKCDLC_03210 2.23e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IEKKCDLC_03211 3.74e-136 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IEKKCDLC_03212 3.34e-210 yraN - - K - - - Transcriptional regulator
IEKKCDLC_03213 1.09e-274 yraM - - S - - - PrpF protein
IEKKCDLC_03214 0.0 - - - EGP - - - Sugar (and other) transporter
IEKKCDLC_03216 3.78e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
IEKKCDLC_03217 1.3e-69 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
IEKKCDLC_03218 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
IEKKCDLC_03219 4.41e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
IEKKCDLC_03220 1.02e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEKKCDLC_03221 9.2e-104 - - - M - - - Ribonuclease
IEKKCDLC_03222 6.92e-184 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
IEKKCDLC_03223 2.76e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
IEKKCDLC_03224 5.16e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
IEKKCDLC_03225 8.99e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
IEKKCDLC_03226 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
IEKKCDLC_03227 5.15e-113 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IEKKCDLC_03228 8.99e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IEKKCDLC_03229 7.1e-202 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
IEKKCDLC_03230 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
IEKKCDLC_03231 5.55e-245 sasA - - T - - - Histidine kinase
IEKKCDLC_03232 3.99e-158 mprA3 - - T - - - COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_03233 5.51e-73 - - - - - - - -
IEKKCDLC_03234 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
IEKKCDLC_03235 4.7e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
IEKKCDLC_03236 3.4e-177 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IEKKCDLC_03237 9.3e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IEKKCDLC_03238 4.87e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IEKKCDLC_03239 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
IEKKCDLC_03240 4.51e-298 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IEKKCDLC_03241 1.83e-148 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IEKKCDLC_03242 6.03e-270 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IEKKCDLC_03243 1.19e-176 yvpB - - NU - - - protein conserved in bacteria
IEKKCDLC_03244 4.65e-95 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
IEKKCDLC_03245 8.12e-158 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IEKKCDLC_03246 1.19e-191 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IEKKCDLC_03247 6e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IEKKCDLC_03248 3.19e-284 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEKKCDLC_03249 9.04e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IEKKCDLC_03250 1.75e-170 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
IEKKCDLC_03251 1.27e-135 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
IEKKCDLC_03252 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
IEKKCDLC_03253 7.66e-66 yvlD - - S ko:K08972 - ko00000 Membrane
IEKKCDLC_03254 8.1e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
IEKKCDLC_03255 3.2e-218 yvlB - - S - - - Putative adhesin
IEKKCDLC_03256 4.87e-66 yvlA - - - - - - -
IEKKCDLC_03257 1.78e-51 yvkN - - - - - - -
IEKKCDLC_03258 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IEKKCDLC_03259 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IEKKCDLC_03260 2.59e-45 csbA - - S - - - protein conserved in bacteria
IEKKCDLC_03261 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
IEKKCDLC_03262 3.7e-143 yvkB - - K - - - Transcriptional regulator
IEKKCDLC_03263 5.92e-298 yvkA - - P - - - -transporter
IEKKCDLC_03264 2.2e-62 - - - Q - - - Thioesterase domain
IEKKCDLC_03265 6.39e-233 - - - S - - - Psort location CytoplasmicMembrane, score
IEKKCDLC_03266 1.23e-58 - - - E - - - Saccharopine dehydrogenase
IEKKCDLC_03267 1.47e-116 - - - V - - - ABC transporter transmembrane region
IEKKCDLC_03268 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
IEKKCDLC_03269 0.0 - - - Q - - - TIGRFAM amino acid adenylation domain
IEKKCDLC_03270 2.94e-42 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IEKKCDLC_03272 6.18e-282 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEKKCDLC_03273 2.47e-73 swrA - - S - - - Swarming motility protein
IEKKCDLC_03274 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
IEKKCDLC_03275 8.15e-303 ywoF - - P - - - Right handed beta helix region
IEKKCDLC_03276 7.34e-197 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IEKKCDLC_03277 8.68e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
IEKKCDLC_03278 5.11e-59 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
IEKKCDLC_03279 6.85e-192 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IEKKCDLC_03280 6.64e-233 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IEKKCDLC_03281 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IEKKCDLC_03282 3.94e-133 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IEKKCDLC_03283 1.35e-89 - - - - - - - -
IEKKCDLC_03284 6.13e-10 fliT - - N ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
IEKKCDLC_03285 3.35e-87 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
IEKKCDLC_03286 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IEKKCDLC_03287 1.97e-139 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IEKKCDLC_03288 2.67e-43 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IEKKCDLC_03289 5.2e-98 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IEKKCDLC_03290 2.8e-108 yviE - - - - - - -
IEKKCDLC_03291 1.2e-208 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
IEKKCDLC_03292 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
IEKKCDLC_03293 2.57e-104 yvyG - - NOU - - - FlgN protein
IEKKCDLC_03294 6.14e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
IEKKCDLC_03295 5.47e-98 yvyF - - S - - - flagellar protein
IEKKCDLC_03296 1.41e-85 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
IEKKCDLC_03297 3.56e-57 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
IEKKCDLC_03298 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IEKKCDLC_03299 1.7e-201 degV - - S - - - protein conserved in bacteria
IEKKCDLC_03300 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEKKCDLC_03301 3.44e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IEKKCDLC_03302 3.43e-154 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
IEKKCDLC_03303 3.83e-230 yvhJ - - K - - - Transcriptional regulator
IEKKCDLC_03304 3.12e-233 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IEKKCDLC_03305 1.28e-300 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
IEKKCDLC_03306 6.92e-186 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
IEKKCDLC_03307 7.05e-148 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
IEKKCDLC_03308 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
IEKKCDLC_03309 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEKKCDLC_03310 3.2e-285 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
IEKKCDLC_03311 0.0 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IEKKCDLC_03312 4.22e-151 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IEKKCDLC_03313 1.99e-264 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
IEKKCDLC_03314 0.0 lytB - - D - - - Stage II sporulation protein
IEKKCDLC_03315 3.45e-40 - - - - - - - -
IEKKCDLC_03316 1.07e-179 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IEKKCDLC_03317 2.43e-234 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IEKKCDLC_03318 3.04e-200 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
IEKKCDLC_03319 1.19e-238 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IEKKCDLC_03320 5.47e-174 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
IEKKCDLC_03321 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IEKKCDLC_03322 7.22e-305 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
IEKKCDLC_03323 2.21e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
IEKKCDLC_03324 3.69e-183 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IEKKCDLC_03325 8.53e-267 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IEKKCDLC_03326 9.45e-180 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IEKKCDLC_03327 1.16e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IEKKCDLC_03328 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
IEKKCDLC_03329 4.46e-254 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
IEKKCDLC_03330 7.36e-273 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
IEKKCDLC_03331 0.0 - - - J ko:K07011 - ko00000 Glycosyl transferase family 2
IEKKCDLC_03332 2.45e-315 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IEKKCDLC_03333 1.89e-228 ywtF_2 - - K - - - Transcriptional regulator
IEKKCDLC_03334 1.07e-201 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IEKKCDLC_03335 9.04e-77 yttA - - S - - - Pfam Transposase IS66
IEKKCDLC_03336 7.83e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IEKKCDLC_03337 6.73e-28 ywtC - - - - - - -
IEKKCDLC_03338 1.39e-280 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IEKKCDLC_03339 2.95e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
IEKKCDLC_03340 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
IEKKCDLC_03341 2.54e-241 gerKA - - EG ko:K06295 - ko00000 Spore germination protein
IEKKCDLC_03342 7.28e-246 - - - E - - - Spore germination protein
IEKKCDLC_03343 2.62e-262 gerKC - - S - - - Spore germination B3/ GerAC like, C-terminal
IEKKCDLC_03344 4.28e-228 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 transcriptional
IEKKCDLC_03345 6.91e-202 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEKKCDLC_03346 4.8e-86 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IEKKCDLC_03347 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IEKKCDLC_03348 5.37e-205 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
IEKKCDLC_03349 6.93e-208 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
IEKKCDLC_03350 1.01e-116 batE - - T - - - Sh3 type 3 domain protein
IEKKCDLC_03351 2.49e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
IEKKCDLC_03352 5.71e-191 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
IEKKCDLC_03353 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
IEKKCDLC_03354 7.59e-215 alsR - - K - - - LysR substrate binding domain
IEKKCDLC_03355 1.27e-307 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IEKKCDLC_03356 3.43e-163 ywrJ - - - - - - -
IEKKCDLC_03357 1.24e-183 cotB - - - ko:K06325 - ko00000 -
IEKKCDLC_03358 6.5e-270 cotH - - M ko:K06330 - ko00000 Spore Coat
IEKKCDLC_03359 5.24e-21 - - - - - - - -
IEKKCDLC_03360 9.88e-145 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IEKKCDLC_03362 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
IEKKCDLC_03363 3.53e-110 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
IEKKCDLC_03364 2.96e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
IEKKCDLC_03365 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
IEKKCDLC_03366 1.51e-173 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IEKKCDLC_03367 3.92e-120 - - - - - - - -
IEKKCDLC_03368 4.24e-94 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
IEKKCDLC_03369 1.36e-85 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
IEKKCDLC_03370 1.1e-135 - - - S - - - Domain of unknown function (DUF1851)
IEKKCDLC_03371 6.06e-62 - - - S - - - LXG domain of WXG superfamily
IEKKCDLC_03372 2.05e-66 - - - - - - - -
IEKKCDLC_03373 0.0 ywqJ - - S - - - Pre-toxin TG
IEKKCDLC_03374 5.99e-50 ywqI - - S - - - Family of unknown function (DUF5344)
IEKKCDLC_03377 1.2e-191 ywqG - - S - - - Domain of unknown function (DUF1963)
IEKKCDLC_03378 1.07e-314 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IEKKCDLC_03379 1.23e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
IEKKCDLC_03380 2.12e-155 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
IEKKCDLC_03381 1.01e-151 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
IEKKCDLC_03382 1.74e-21 - - - - - - - -
IEKKCDLC_03383 0.0 ywqB - - S - - - SWIM zinc finger
IEKKCDLC_03384 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
IEKKCDLC_03385 7.5e-202 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
IEKKCDLC_03386 1.18e-181 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
IEKKCDLC_03387 5.13e-77 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
IEKKCDLC_03388 4.49e-82 ywpG - - - - - - -
IEKKCDLC_03389 9.16e-91 ywpF - - S - - - YwpF-like protein
IEKKCDLC_03390 7.6e-74 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IEKKCDLC_03391 3.15e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IEKKCDLC_03392 1.56e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
IEKKCDLC_03393 3.81e-187 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IEKKCDLC_03394 1.03e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
IEKKCDLC_03395 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
IEKKCDLC_03396 5.93e-60 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
IEKKCDLC_03397 3.58e-93 ywoH - - K - - - transcriptional
IEKKCDLC_03398 2.89e-272 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
IEKKCDLC_03399 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
IEKKCDLC_03400 3.13e-309 ywoD - - EGP - - - Major facilitator superfamily
IEKKCDLC_03401 1.37e-133 yjgF - - Q - - - Isochorismatase family
IEKKCDLC_03402 1.32e-291 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
IEKKCDLC_03403 5.28e-76 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
IEKKCDLC_03404 6e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
IEKKCDLC_03405 5.79e-132 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
IEKKCDLC_03406 6.63e-95 ywnJ - - S - - - VanZ like family
IEKKCDLC_03407 1.31e-188 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
IEKKCDLC_03408 2.27e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
IEKKCDLC_03410 2.55e-90 ywnF - - S - - - Family of unknown function (DUF5392)
IEKKCDLC_03411 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEKKCDLC_03412 1.97e-79 ywnC - - S - - - Family of unknown function (DUF5362)
IEKKCDLC_03413 5.3e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
IEKKCDLC_03415 3.09e-88 ywnA - - K - - - Transcriptional regulator
IEKKCDLC_03416 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IEKKCDLC_03417 1.85e-82 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
IEKKCDLC_03418 2.86e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
IEKKCDLC_03419 2.01e-16 csbD - - K - - - CsbD-like
IEKKCDLC_03420 1.05e-107 ywmF - - S - - - Peptidase M50
IEKKCDLC_03421 4.43e-116 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
IEKKCDLC_03422 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IEKKCDLC_03423 5.24e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IEKKCDLC_03425 8.69e-158 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IEKKCDLC_03426 1.5e-159 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
IEKKCDLC_03427 5.75e-242 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
IEKKCDLC_03428 7.05e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEKKCDLC_03429 1.62e-172 ywmB - - S - - - TATA-box binding
IEKKCDLC_03430 2.25e-45 ywzB - - S - - - membrane
IEKKCDLC_03431 1.76e-118 ywmA - - - - - - -
IEKKCDLC_03432 8.24e-83 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
IEKKCDLC_03433 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEKKCDLC_03434 1.1e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IEKKCDLC_03435 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEKKCDLC_03436 3.23e-115 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEKKCDLC_03437 1.66e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IEKKCDLC_03438 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEKKCDLC_03439 1.05e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
IEKKCDLC_03440 4.49e-80 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
IEKKCDLC_03441 4.34e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IEKKCDLC_03442 1.7e-300 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IEKKCDLC_03443 1.05e-124 ywlG - - S - - - Belongs to the UPF0340 family
IEKKCDLC_03444 6.74e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
IEKKCDLC_03445 2.08e-101 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEKKCDLC_03446 3.35e-119 mntP - - P - - - Probably functions as a manganese efflux pump
IEKKCDLC_03447 7.58e-244 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IEKKCDLC_03448 2.45e-98 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
IEKKCDLC_03449 6.57e-153 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
IEKKCDLC_03450 2.08e-79 ywlA - - S - - - Uncharacterised protein family (UPF0715)
IEKKCDLC_03452 6.95e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IEKKCDLC_03453 1.11e-244 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IEKKCDLC_03454 9.07e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEKKCDLC_03455 1.48e-123 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IEKKCDLC_03456 2.02e-202 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
IEKKCDLC_03457 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
IEKKCDLC_03458 5.56e-136 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
IEKKCDLC_03459 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
IEKKCDLC_03460 5.13e-304 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IEKKCDLC_03461 1.43e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
IEKKCDLC_03462 5.55e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEKKCDLC_03463 2.22e-144 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IEKKCDLC_03464 5.51e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
IEKKCDLC_03465 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
IEKKCDLC_03466 8.11e-121 ywjG - - S - - - Domain of unknown function (DUF2529)
IEKKCDLC_03467 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IEKKCDLC_03468 1.39e-74 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IEKKCDLC_03469 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
IEKKCDLC_03470 2.97e-286 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IEKKCDLC_03471 2.82e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IEKKCDLC_03472 6.53e-58 ywjC - - - - - - -
IEKKCDLC_03473 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
IEKKCDLC_03474 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEKKCDLC_03475 5.01e-135 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEKKCDLC_03476 1.45e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
IEKKCDLC_03477 7.34e-123 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
IEKKCDLC_03478 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
IEKKCDLC_03479 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEKKCDLC_03480 2.05e-109 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
IEKKCDLC_03481 5.91e-176 ywiC - - S - - - YwiC-like protein
IEKKCDLC_03482 7.71e-167 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
IEKKCDLC_03483 1.05e-273 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
IEKKCDLC_03484 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
IEKKCDLC_03485 1.95e-56 ywiB - - S - - - protein conserved in bacteria
IEKKCDLC_03486 1.16e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
IEKKCDLC_03488 9.15e-41 ydcG - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
IEKKCDLC_03489 2.41e-45 - - - - - - - -
IEKKCDLC_03490 1.18e-38 - - - S - - - Domain of unknown function (DUF4177)
IEKKCDLC_03492 1.2e-100 - - - CP - - - Membrane
IEKKCDLC_03495 1.22e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IEKKCDLC_03496 6.45e-203 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IEKKCDLC_03497 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
IEKKCDLC_03498 6.08e-106 - - - - - - - -
IEKKCDLC_03499 3.88e-123 ywhD - - S - - - YwhD family
IEKKCDLC_03500 4.48e-152 ywhC - - S - - - Peptidase family M50
IEKKCDLC_03501 2.37e-34 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
IEKKCDLC_03502 4.16e-93 ywhA - - K - - - Transcriptional regulator
IEKKCDLC_03503 5.69e-315 potE5 - - E ko:K03294 - ko00000 C-terminus of AA_permease
IEKKCDLC_03504 2.02e-115 ywgA - - - ko:K09388 - ko00000 -
IEKKCDLC_03505 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
IEKKCDLC_03506 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
IEKKCDLC_03507 2.48e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
IEKKCDLC_03508 5.36e-68 - - - K ko:K10947 - ko00000,ko03000 PadR family transcriptional regulator
IEKKCDLC_03509 1.87e-120 - - - S - - - membrane
IEKKCDLC_03510 3.46e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_03511 1.47e-215 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC transporter (permease)
IEKKCDLC_03514 8.13e-239 - - - - - - - -
IEKKCDLC_03516 9.14e-204 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IEKKCDLC_03517 3.89e-211 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
IEKKCDLC_03518 9.79e-213 - - - S - - - Conserved hypothetical protein 698
IEKKCDLC_03519 5.83e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
IEKKCDLC_03520 4.87e-187 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
IEKKCDLC_03521 2.94e-181 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
IEKKCDLC_03522 1.82e-296 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
IEKKCDLC_03523 8.14e-265 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IEKKCDLC_03524 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IEKKCDLC_03525 8.05e-181 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IEKKCDLC_03526 1.19e-176 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IEKKCDLC_03527 5.69e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IEKKCDLC_03528 2.74e-284 ywfA - - EGP - - - -transporter
IEKKCDLC_03529 4.68e-263 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
IEKKCDLC_03530 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IEKKCDLC_03531 0.0 rocB - - E - - - arginine degradation protein
IEKKCDLC_03532 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
IEKKCDLC_03533 6.34e-314 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
IEKKCDLC_03534 6.37e-77 - - - - - - - -
IEKKCDLC_03535 2.32e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
IEKKCDLC_03536 1.16e-208 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IEKKCDLC_03537 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IEKKCDLC_03538 9.8e-178 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IEKKCDLC_03539 9.14e-239 spsG - - M - - - Spore Coat
IEKKCDLC_03540 5.44e-176 spsF - - M ko:K07257 - ko00000 Spore Coat
IEKKCDLC_03541 1.67e-272 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
IEKKCDLC_03542 1.3e-203 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
IEKKCDLC_03543 1.25e-282 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
IEKKCDLC_03544 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
IEKKCDLC_03545 9.06e-184 spsA - - M - - - Spore Coat
IEKKCDLC_03546 6.51e-88 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IEKKCDLC_03547 2.17e-76 ywdK - - S - - - small membrane protein
IEKKCDLC_03548 3.96e-293 ywdJ - - F - - - Xanthine uracil
IEKKCDLC_03549 1.57e-62 ywdI - - S - - - Family of unknown function (DUF5327)
IEKKCDLC_03550 8.43e-170 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IEKKCDLC_03551 2.82e-193 ywdF - - S - - - Glycosyltransferase like family 2
IEKKCDLC_03552 4.13e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
IEKKCDLC_03553 3.52e-26 ywdA - - - - - - -
IEKKCDLC_03554 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
IEKKCDLC_03555 9.04e-317 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_03557 2.23e-194 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IEKKCDLC_03559 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IEKKCDLC_03560 9.46e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IEKKCDLC_03561 1.14e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
IEKKCDLC_03562 3.11e-270 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
IEKKCDLC_03563 6.77e-100 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
IEKKCDLC_03564 1.03e-50 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
IEKKCDLC_03565 8.22e-85 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IEKKCDLC_03566 4.91e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
IEKKCDLC_03567 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IEKKCDLC_03568 2.21e-228 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IEKKCDLC_03569 5.74e-48 ydaS - - S - - - membrane
IEKKCDLC_03570 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
IEKKCDLC_03571 1.41e-286 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IEKKCDLC_03572 1.71e-81 gtcA - - S - - - GtrA-like protein
IEKKCDLC_03573 6.43e-146 - - - K - - - Bacterial regulatory proteins, tetR family
IEKKCDLC_03575 7.5e-168 - - - H - - - Methionine biosynthesis protein MetW
IEKKCDLC_03576 4.9e-172 - - - S - - - Streptomycin biosynthesis protein StrF
IEKKCDLC_03577 1.79e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
IEKKCDLC_03578 1.8e-308 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
IEKKCDLC_03579 5.56e-144 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IEKKCDLC_03580 1.12e-176 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IEKKCDLC_03581 4.83e-202 ywbI - - K - - - Transcriptional regulator
IEKKCDLC_03582 9.02e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IEKKCDLC_03583 6.47e-144 ywbG - - M - - - effector of murein hydrolase
IEKKCDLC_03584 1.07e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
IEKKCDLC_03585 2.4e-182 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
IEKKCDLC_03586 1.37e-216 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
IEKKCDLC_03587 3.08e-286 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
IEKKCDLC_03588 1.76e-86 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
IEKKCDLC_03589 3.28e-315 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEKKCDLC_03590 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
IEKKCDLC_03591 2.56e-208 gspA - - M - - - General stress
IEKKCDLC_03592 1.04e-103 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IEKKCDLC_03593 8.58e-28 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
IEKKCDLC_03594 4.37e-214 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
IEKKCDLC_03595 7.08e-18 - - - S - - - D-Ala-teichoic acid biosynthesis protein
IEKKCDLC_03596 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_03597 1.04e-292 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
IEKKCDLC_03598 1.96e-49 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEKKCDLC_03599 3.76e-290 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IEKKCDLC_03600 1.35e-261 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
IEKKCDLC_03601 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IEKKCDLC_03602 1.18e-67 licA 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_03603 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEKKCDLC_03604 4.46e-66 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
IEKKCDLC_03605 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
IEKKCDLC_03606 5.36e-144 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
IEKKCDLC_03607 1.91e-219 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_03608 4.83e-231 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEKKCDLC_03609 9.23e-214 cbrA3 - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IEKKCDLC_03610 1.57e-77 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
IEKKCDLC_03611 7.34e-290 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IEKKCDLC_03612 1.18e-66 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_03613 7.89e-66 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
IEKKCDLC_03614 7.31e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEKKCDLC_03615 0.0 ydhP 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
IEKKCDLC_03616 1.04e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
IEKKCDLC_03617 2.15e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
IEKKCDLC_03618 8.82e-266 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
IEKKCDLC_03619 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IEKKCDLC_03620 7.89e-246 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
IEKKCDLC_03621 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
IEKKCDLC_03622 2.94e-199 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEKKCDLC_03623 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
IEKKCDLC_03624 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
IEKKCDLC_03625 7.86e-242 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
IEKKCDLC_03626 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
IEKKCDLC_03627 3.89e-288 cimH - - C - - - COG3493 Na citrate symporter
IEKKCDLC_03628 5.7e-199 yxkH - - G - - - Polysaccharide deacetylase
IEKKCDLC_03629 1.51e-260 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
IEKKCDLC_03630 1.16e-211 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
IEKKCDLC_03631 4.82e-190 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEKKCDLC_03632 2.68e-120 yxkC - - S - - - Domain of unknown function (DUF4352)
IEKKCDLC_03633 2.19e-248 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
IEKKCDLC_03634 2.22e-298 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
IEKKCDLC_03637 8.67e-111 yxjI - - S - - - LURP-one-related
IEKKCDLC_03638 2.8e-278 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
IEKKCDLC_03639 3.73e-206 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
IEKKCDLC_03640 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEKKCDLC_03641 3.75e-126 - - - T - - - Domain of unknown function (DUF4163)
IEKKCDLC_03642 5.58e-61 yxiS - - - - - - -
IEKKCDLC_03643 5.95e-216 - - - L - - - DNA synthesis involved in DNA repair
IEKKCDLC_03644 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
IEKKCDLC_03645 9.49e-283 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
IEKKCDLC_03646 3.44e-186 bglS - - M - - - licheninase activity
IEKKCDLC_03647 3.41e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
IEKKCDLC_03648 9e-283 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
IEKKCDLC_03649 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IEKKCDLC_03652 1.95e-78 - - - S - - - SMI1-KNR4 cell-wall
IEKKCDLC_03653 1.15e-62 yxiI - - S - - - Protein of unknown function (DUF2716)
IEKKCDLC_03654 2.38e-27 - - - - - - - -
IEKKCDLC_03656 6.24e-131 - - - - - - - -
IEKKCDLC_03657 3.33e-101 - - - - - - - -
IEKKCDLC_03661 2.09e-91 yxiG - - - - - - -
IEKKCDLC_03662 4.19e-87 yxxG - - - - - - -
IEKKCDLC_03667 5.15e-67 - - - - - - - -
IEKKCDLC_03668 0.0 wapA - - M - - - COG3209 Rhs family protein
IEKKCDLC_03669 3.83e-257 pelB 4.2.2.10, 4.2.2.2 - G ko:K01728,ko:K01732 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
IEKKCDLC_03670 8.44e-208 yxxF - - EG - - - EamA-like transporter family
IEKKCDLC_03671 5.75e-93 yxiE - - T - - - Belongs to the universal stress protein A family
IEKKCDLC_03672 0.0 - - - L - - - HKD family nuclease
IEKKCDLC_03673 2.39e-85 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IEKKCDLC_03674 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
IEKKCDLC_03675 2.45e-103 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IEKKCDLC_03676 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
IEKKCDLC_03677 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IEKKCDLC_03678 1.35e-300 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
IEKKCDLC_03679 5.01e-227 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IEKKCDLC_03680 0.0 hutM - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IEKKCDLC_03681 1.1e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
IEKKCDLC_03682 4.04e-265 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IEKKCDLC_03683 4.09e-145 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IEKKCDLC_03684 1e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IEKKCDLC_03685 5.46e-192 yxeH - - S - - - hydrolases of the HAD superfamily
IEKKCDLC_03688 2.06e-42 yxeE - - - - - - -
IEKKCDLC_03689 5.09e-35 yxeD - - - - - - -
IEKKCDLC_03690 2.8e-46 - - - - - - - -
IEKKCDLC_03691 8.33e-228 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
IEKKCDLC_03692 9.89e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
IEKKCDLC_03693 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
IEKKCDLC_03694 3.28e-182 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_03695 7.95e-224 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_03696 5.42e-158 yxdJ - - T ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_03697 0.0 - - - T - - - Histidine kinase
IEKKCDLC_03698 6.65e-178 yvrH - - T - - - Transcriptional regulator
IEKKCDLC_03699 2.52e-209 - - - V ko:K20459,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
IEKKCDLC_03700 1.94e-167 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 permease
IEKKCDLC_03701 1.89e-170 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
IEKKCDLC_03702 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IEKKCDLC_03703 1.03e-201 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IEKKCDLC_03704 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
IEKKCDLC_03705 6.3e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IEKKCDLC_03706 2.59e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
IEKKCDLC_03707 1.88e-222 iolE 4.2.1.44 - H ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IEKKCDLC_03708 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IEKKCDLC_03709 1.69e-232 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IEKKCDLC_03710 2.08e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IEKKCDLC_03711 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IEKKCDLC_03712 8.29e-173 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
IEKKCDLC_03713 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
IEKKCDLC_03714 1.1e-313 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IEKKCDLC_03715 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
IEKKCDLC_03717 4.15e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
IEKKCDLC_03718 1.07e-131 desR - - T ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IEKKCDLC_03719 9.69e-254 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_03720 1.56e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
IEKKCDLC_03721 2.3e-276 yxbF - - K - - - Bacterial regulatory proteins, tetR family
IEKKCDLC_03722 0.0 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
IEKKCDLC_03723 5.76e-188 yxaL - - S - - - PQQ-like domain
IEKKCDLC_03724 8.36e-84 - - - S - - - Family of unknown function (DUF5391)
IEKKCDLC_03725 2.01e-66 arsR3 - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
IEKKCDLC_03726 1.97e-258 - - - EGP - - - Major Facilitator Superfamily
IEKKCDLC_03727 9.49e-98 yxaI - - S - - - membrane protein domain
IEKKCDLC_03728 3.29e-163 - - - E - - - Ring-cleavage extradiol dioxygenase
IEKKCDLC_03729 1.61e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
IEKKCDLC_03730 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
IEKKCDLC_03731 3.95e-292 - - - S - - - Fic/DOC family
IEKKCDLC_03732 8.71e-313 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
IEKKCDLC_03733 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IEKKCDLC_03734 4.92e-110 pucE 1.2.5.3 - C ko:K03518 - ko00000,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IEKKCDLC_03735 6.65e-198 - - - C - - - COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IEKKCDLC_03736 0.0 - - - C - - - COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IEKKCDLC_03737 1.52e-118 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
IEKKCDLC_03738 2.63e-240 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IEKKCDLC_03739 1.99e-237 - - - S - - - Fusaric acid resistance protein-like
IEKKCDLC_03740 3.9e-16 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
IEKKCDLC_03741 3.27e-45 - - - - - - - -
IEKKCDLC_03743 1.67e-104 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IEKKCDLC_03747 1.69e-274 yycP - - - - - - -
IEKKCDLC_03748 5.84e-172 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IEKKCDLC_03749 1.11e-235 - - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
IEKKCDLC_03750 1.02e-113 yycN - - K - - - Acetyltransferase
IEKKCDLC_03752 9.49e-262 - - - S ko:K06361,ko:K06365,ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Histidine kinase
IEKKCDLC_03753 1.86e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
IEKKCDLC_03754 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
IEKKCDLC_03755 9.68e-295 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
IEKKCDLC_03756 3.8e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IEKKCDLC_03757 2.69e-57 sdpR - - K - - - transcriptional
IEKKCDLC_03758 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IEKKCDLC_03759 4.53e-189 - 1.14.11.27 - P ko:K10277 - ko00000,ko01000,ko03036 peptidyl-arginine hydroxylation
IEKKCDLC_03760 0.0 - - - S - - - ABC transporter
IEKKCDLC_03761 2.47e-256 - - - S - - - Major Facilitator Superfamily
IEKKCDLC_03762 0.0 - - - - - - - -
IEKKCDLC_03763 9e-241 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
IEKKCDLC_03764 0.0 - 2.7.13.3 - T ko:K02484 - ko00000,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
IEKKCDLC_03765 9.23e-14 phoP1 - - KT ko:K02483 - ko00000,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_03766 1.63e-278 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IEKKCDLC_03767 2.82e-191 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IEKKCDLC_03768 4.16e-196 yycI - - S - - - protein conserved in bacteria
IEKKCDLC_03769 0.0 yycH - - S - - - protein conserved in bacteria
IEKKCDLC_03770 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
IEKKCDLC_03771 1.51e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IEKKCDLC_03776 1.06e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEKKCDLC_03777 1.63e-96 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEKKCDLC_03778 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
IEKKCDLC_03779 2.21e-38 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
IEKKCDLC_03781 7.28e-25 yycC - - K - - - YycC-like protein
IEKKCDLC_03782 1.92e-51 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase activity
IEKKCDLC_03783 5.37e-307 - - - M - - - Glycosyltransferase Family 4
IEKKCDLC_03784 3.03e-257 - - - S - - - Ecdysteroid kinase
IEKKCDLC_03785 9.34e-297 - - - S - - - Carbamoyl-phosphate synthase L chain, ATP binding domain
IEKKCDLC_03786 5.47e-298 - - - M - - - Glycosyltransferase Family 4
IEKKCDLC_03787 2.52e-156 - - - S - - - GlcNAc-PI de-N-acetylase
IEKKCDLC_03788 8.29e-115 - - - KLT - - - COG0515 Serine threonine protein kinase
IEKKCDLC_03789 1.58e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
IEKKCDLC_03790 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
IEKKCDLC_03791 5.01e-204 yybS - - S - - - membrane
IEKKCDLC_03793 3.33e-111 cotF - - M ko:K06329 - ko00000 Spore coat protein
IEKKCDLC_03794 4.56e-87 yybR - - K - - - Transcriptional regulator
IEKKCDLC_03795 6.94e-210 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
IEKKCDLC_03796 4.13e-197 ypaH - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IEKKCDLC_03797 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
IEKKCDLC_03798 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
IEKKCDLC_03799 2.69e-149 - - - K - - - FCD domain
IEKKCDLC_03800 5.75e-119 - - - S - - - PFAM DinB family protein
IEKKCDLC_03801 5.75e-205 - - - G - - - Major Facilitator Superfamily
IEKKCDLC_03802 3.18e-103 eamA1 - - EG - - - spore germination
IEKKCDLC_03803 3.22e-73 ypaA - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
IEKKCDLC_03804 1.7e-148 ydgI - - C - - - nitroreductase
IEKKCDLC_03805 1.37e-89 - - - K - - - Winged helix DNA-binding domain
IEKKCDLC_03806 1.38e-196 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
IEKKCDLC_03807 1.3e-99 yybA - - K - - - transcriptional
IEKKCDLC_03808 3.13e-99 yjcF - - S - - - Acetyltransferase (GNAT) domain
IEKKCDLC_03809 2.02e-212 - - - M - - - Domain of Unknown Function (DUF1259)
IEKKCDLC_03810 2.02e-88 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
IEKKCDLC_03811 2.44e-211 - - - K - - - Transcriptional regulator
IEKKCDLC_03812 3.06e-177 bdh 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IEKKCDLC_03813 3.69e-313 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IEKKCDLC_03814 3.85e-164 - - - EG - - - EamA-like transporter family
IEKKCDLC_03815 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
IEKKCDLC_03816 3.6e-211 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
IEKKCDLC_03817 2.81e-316 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
IEKKCDLC_03818 1.99e-87 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IEKKCDLC_03819 4.85e-232 ccpB - - K - - - Transcriptional regulator
IEKKCDLC_03820 1.98e-185 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
IEKKCDLC_03821 2.89e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IEKKCDLC_03822 2.77e-140 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
IEKKCDLC_03823 1.11e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IEKKCDLC_03824 4.77e-99 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IEKKCDLC_03825 2.9e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
IEKKCDLC_03826 5.42e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IEKKCDLC_03827 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IEKKCDLC_03828 1.82e-45 yyzM - - S - - - protein conserved in bacteria
IEKKCDLC_03829 3.36e-225 yyaD - - S - - - Membrane
IEKKCDLC_03830 1.21e-110 yhhY - - K - - - FR47-like protein
IEKKCDLC_03831 4.91e-144 yyaC - - S - - - Sporulation protein YyaC
IEKKCDLC_03832 1.43e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
IEKKCDLC_03833 1.18e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
IEKKCDLC_03834 6.61e-195 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IEKKCDLC_03835 2.29e-164 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IEKKCDLC_03836 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IEKKCDLC_03837 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IEKKCDLC_03838 2.3e-142 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
IEKKCDLC_03839 2.12e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEKKCDLC_03840 1.99e-71 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)