Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HEFKFHKI_00002	1.13e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HEFKFHKI_00003	3.61e-209	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HEFKFHKI_00004	2.64e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEFKFHKI_00005	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEFKFHKI_00006	4.47e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HEFKFHKI_00007	1.6e-77	-	-	-	-	-	-	-	-
HEFKFHKI_00008	1.5e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HEFKFHKI_00009	1.61e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEFKFHKI_00010	3.44e-70	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HEFKFHKI_00011	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEFKFHKI_00012	3.83e-230	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEFKFHKI_00013	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEFKFHKI_00014	1.25e-261	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEFKFHKI_00015	4.49e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEFKFHKI_00016	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEFKFHKI_00017	6.52e-289	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEFKFHKI_00018	1.57e-92	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEFKFHKI_00019	1.11e-54	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HEFKFHKI_00020	1.84e-190	ylmH	-	-	S	-	-	-	S4 domain protein
HEFKFHKI_00021	5.37e-97	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HEFKFHKI_00022	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEFKFHKI_00023	5.69e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HEFKFHKI_00024	2.48e-129	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HEFKFHKI_00025	1.54e-33	-	-	-	-	-	-	-	-
HEFKFHKI_00026	3.4e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEFKFHKI_00027	9.43e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HEFKFHKI_00028	5.58e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HEFKFHKI_00029	2.15e-286	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEFKFHKI_00030	1.99e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HEFKFHKI_00031	1.1e-156	-	-	-	S	-	-	-	repeat protein
HEFKFHKI_00032	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEFKFHKI_00033	3.64e-224	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEFKFHKI_00034	1.31e-242	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEFKFHKI_00035	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEFKFHKI_00036	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEFKFHKI_00037	1.2e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEFKFHKI_00038	1.71e-285	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEFKFHKI_00039	5.62e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEFKFHKI_00040	9.39e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEFKFHKI_00041	1.51e-281	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEFKFHKI_00042	4.47e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEFKFHKI_00043	4.66e-103	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Putative sugar diacid recognition
HEFKFHKI_00044	2.31e-281	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HEFKFHKI_00045	1.73e-270	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HEFKFHKI_00046	5.28e-76	-	-	-	-	-	-	-	-
HEFKFHKI_00048	2.43e-248	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HEFKFHKI_00049	4.37e-39	-	-	-	-	-	-	-	-
HEFKFHKI_00050	2.71e-235	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HEFKFHKI_00051	9.99e-44	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HEFKFHKI_00052	2.3e-106	-	-	-	-	-	-	-	-
HEFKFHKI_00053	8.3e-134	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEFKFHKI_00054	2.44e-267	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HEFKFHKI_00055	2.31e-232	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HEFKFHKI_00056	1.34e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEFKFHKI_00057	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HEFKFHKI_00058	2.87e-63	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HEFKFHKI_00059	2.12e-178	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HEFKFHKI_00060	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HEFKFHKI_00061	2.75e-286	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEFKFHKI_00062	3.83e-61	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HEFKFHKI_00063	2.37e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HEFKFHKI_00064	3.05e-116	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEFKFHKI_00065	2.58e-253	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HEFKFHKI_00066	8.7e-141	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HEFKFHKI_00067	2.47e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HEFKFHKI_00068	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HEFKFHKI_00069	5.84e-203	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HEFKFHKI_00070	1.44e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HEFKFHKI_00071	1.74e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEFKFHKI_00072	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEFKFHKI_00073	1.3e-210	-	-	-	S	-	-	-	Tetratricopeptide repeat
HEFKFHKI_00074	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEFKFHKI_00075	5.54e-303	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEFKFHKI_00076	5.06e-298	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEFKFHKI_00077	2.01e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HEFKFHKI_00078	1.11e-78	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HEFKFHKI_00079	6.36e-296	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HEFKFHKI_00080	7.67e-252	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEFKFHKI_00081	2.29e-276	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HEFKFHKI_00082	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEFKFHKI_00083	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEFKFHKI_00084	4.52e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEFKFHKI_00085	9.97e-245	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEFKFHKI_00086	1.11e-260	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEFKFHKI_00087	1.86e-62	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HEFKFHKI_00088	2.15e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HEFKFHKI_00089	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEFKFHKI_00090	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEFKFHKI_00091	8.03e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HEFKFHKI_00092	3.62e-100	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEFKFHKI_00093	3.75e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HEFKFHKI_00094	7.15e-122	cvpA	-	-	S	-	-	-	Colicin V production protein
HEFKFHKI_00095	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEFKFHKI_00096	2.86e-72	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HEFKFHKI_00097	3.01e-126	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HEFKFHKI_00098	3.41e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HEFKFHKI_00099	1.53e-138	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEFKFHKI_00100	1.16e-124	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HEFKFHKI_00101	1.79e-100	ykuL	-	-	S	-	-	-	(CBS) domain
HEFKFHKI_00102	1.4e-198	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HEFKFHKI_00103	1.6e-190	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HEFKFHKI_00104	1.54e-71	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEFKFHKI_00105	2.93e-58	-	-	-	-	-	-	-	-
HEFKFHKI_00106	6.25e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HEFKFHKI_00107	1.7e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HEFKFHKI_00108	1.03e-181	-	-	-	-	-	-	-	-
HEFKFHKI_00109	1.22e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HEFKFHKI_00110	8.77e-237	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HEFKFHKI_00111	2.95e-240	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HEFKFHKI_00112	6.31e-62	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HEFKFHKI_00113	3.65e-103	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HEFKFHKI_00114	3.65e-60	-	-	-	-	-	-	-	-
HEFKFHKI_00115	1.01e-95	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
HEFKFHKI_00117	5.09e-186	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HEFKFHKI_00118	1.36e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEFKFHKI_00119	2.01e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HEFKFHKI_00120	3.03e-129	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HEFKFHKI_00121	1.44e-180	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEFKFHKI_00122	7.15e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HEFKFHKI_00123	1.29e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HEFKFHKI_00124	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HEFKFHKI_00125	7.76e-279	-	-	-	P	-	-	-	Voltage gated chloride channel
HEFKFHKI_00126	5.59e-290	sptS	-	-	T	-	-	-	Histidine kinase
HEFKFHKI_00127	1.1e-153	dltr	-	-	K	-	-	-	response regulator
HEFKFHKI_00128	2.92e-111	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HEFKFHKI_00129	2.26e-90	-	-	-	V	-	-	-	Abi-like protein
HEFKFHKI_00130	1.43e-17	-	-	-	V	-	-	-	Abi-like protein
HEFKFHKI_00132	5.38e-51	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HEFKFHKI_00133	6.73e-40	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HEFKFHKI_00134	9.75e-91	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HEFKFHKI_00135	8.01e-316	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEFKFHKI_00137	1.15e-109	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HEFKFHKI_00138	4.1e-308	yhdP	-	-	S	-	-	-	Transporter associated domain
HEFKFHKI_00139	9.4e-197	-	-	-	V	-	-	-	(ABC) transporter
HEFKFHKI_00140	1.9e-115	-	-	-	GM	-	-	-	epimerase
HEFKFHKI_00141	1.51e-117	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HEFKFHKI_00142	8.16e-103	yybA	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_00143	7.74e-173	XK27_07210	-	-	S	-	-	-	B3 4 domain
HEFKFHKI_00144	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEFKFHKI_00145	2.51e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEFKFHKI_00146	3.1e-289	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HEFKFHKI_00147	1.31e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEFKFHKI_00149	4.69e-239	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFKFHKI_00150	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_00151	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEFKFHKI_00152	2.98e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HEFKFHKI_00153	4.7e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HEFKFHKI_00154	7.96e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HEFKFHKI_00155	2.57e-227	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HEFKFHKI_00156	1.81e-309	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEFKFHKI_00157	1.76e-45	ywzB	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HEFKFHKI_00158	9e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HEFKFHKI_00159	9.11e-123	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEFKFHKI_00160	5.98e-206	-	-	-	S	-	-	-	Alpha beta hydrolase
HEFKFHKI_00161	1.03e-202	gspA	-	-	M	-	-	-	family 8
HEFKFHKI_00162	1.76e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HEFKFHKI_00169	5.03e-96	-	-	-	F	-	-	-	deoxynucleoside kinase
HEFKFHKI_00170	2.41e-53	-	-	-	-	-	-	-	-
HEFKFHKI_00171	1.1e-280	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HEFKFHKI_00172	3.86e-185	XK27_00940	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Putative cyclase
HEFKFHKI_00173	8.07e-204	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HEFKFHKI_00174	8.36e-231	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEFKFHKI_00175	7.41e-57	-	-	-	S	ko:K09790	-	ko00000	Protein of unknown function (DUF454)
HEFKFHKI_00176	5.07e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HEFKFHKI_00177	2.7e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HEFKFHKI_00178	3.57e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEFKFHKI_00179	5.57e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEFKFHKI_00180	5.02e-29	-	-	-	-	-	-	-	-
HEFKFHKI_00181	9.35e-116	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HEFKFHKI_00182	3.73e-203	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HEFKFHKI_00183	3.32e-71	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HEFKFHKI_00184	9.7e-91	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HEFKFHKI_00185	2.59e-230	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
HEFKFHKI_00186	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HEFKFHKI_00187	9.55e-44	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEFKFHKI_00188	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
HEFKFHKI_00189	5.51e-45	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HEFKFHKI_00190	1.52e-50	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HEFKFHKI_00191	1.33e-117	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
HEFKFHKI_00192	1.99e-124	-	-	-	L	-	-	-	Transposase
HEFKFHKI_00193	1.73e-72	-	-	-	L	-	-	-	Transposase
HEFKFHKI_00194	6.84e-53	-	-	-	-	-	-	-	-
HEFKFHKI_00195	1.66e-23	-	-	-	-	-	-	-	-
HEFKFHKI_00201	2.9e-76	-	-	-	-	-	-	-	-
HEFKFHKI_00205	1.62e-189	-	-	-	S	-	-	-	Terminase-like family
HEFKFHKI_00206	1.82e-11	-	-	-	-	-	-	-	-
HEFKFHKI_00213	5.46e-119	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HEFKFHKI_00215	4.77e-09	-	-	-	D	-	-	-	cell division
HEFKFHKI_00222	1.02e-196	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEFKFHKI_00223	2.23e-261	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEFKFHKI_00224	9.64e-141	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HEFKFHKI_00225	2.73e-206	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEFKFHKI_00226	8.88e-138	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HEFKFHKI_00227	3.7e-297	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HEFKFHKI_00228	1.17e-136	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HEFKFHKI_00229	5.76e-128	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HEFKFHKI_00230	1.03e-206	-	-	-	J	-	-	-	Methyltransferase
HEFKFHKI_00231	5.16e-289	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HEFKFHKI_00232	2.63e-115	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEFKFHKI_00233	1.2e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HEFKFHKI_00234	1.38e-228	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HEFKFHKI_00235	1.84e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEFKFHKI_00236	9.61e-137	-	-	-	-	-	-	-	-
HEFKFHKI_00237	2.58e-52	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEFKFHKI_00251	1.06e-18	-	-	-	S	ko:K09946	-	ko00000	Domain of unknown function (DUF1508)
HEFKFHKI_00255	3.97e-198	-	-	-	EG	-	-	-	EamA-like transporter family
HEFKFHKI_00256	1.15e-152	-	-	-	L	-	-	-	Integrase
HEFKFHKI_00257	8.81e-205	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HEFKFHKI_00261	7.83e-71	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HEFKFHKI_00262	5.1e-84	-	-	-	L	-	-	-	DnaD domain protein
HEFKFHKI_00263	1.51e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEFKFHKI_00264	4.93e-216	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEFKFHKI_00266	1.49e-54	-	-	-	-	-	-	-	-
HEFKFHKI_00267	4.61e-61	-	-	-	-	-	-	-	-
HEFKFHKI_00268	1.43e-51	-	-	-	S	-	-	-	Cytochrome B5
HEFKFHKI_00269	1.11e-201	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HEFKFHKI_00270	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HEFKFHKI_00271	1.54e-191	-	-	-	O	-	-	-	Band 7 protein
HEFKFHKI_00272	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HEFKFHKI_00273	2.9e-169	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HEFKFHKI_00274	3.69e-87	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HEFKFHKI_00275	6.23e-161	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HEFKFHKI_00276	1.19e-229	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEFKFHKI_00277	5.79e-214	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HEFKFHKI_00278	4.39e-244	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HEFKFHKI_00279	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HEFKFHKI_00280	6.01e-115	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HEFKFHKI_00281	8.91e-248	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEFKFHKI_00282	4.11e-274	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HEFKFHKI_00283	1.21e-217	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HEFKFHKI_00284	3.63e-220	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HEFKFHKI_00285	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HEFKFHKI_00286	9.09e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HEFKFHKI_00287	5e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HEFKFHKI_00288	2.42e-208	-	-	-	EG	-	-	-	EamA-like transporter family
HEFKFHKI_00289	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HEFKFHKI_00290	1.41e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEFKFHKI_00291	1.05e-133	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HEFKFHKI_00292	6.82e-74	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEFKFHKI_00293	4.83e-108	-	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HEFKFHKI_00294	1.03e-283	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HEFKFHKI_00295	7.37e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HEFKFHKI_00296	2.58e-85	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HEFKFHKI_00297	3.61e-96	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEFKFHKI_00298	4.12e-224	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEFKFHKI_00299	1.85e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HEFKFHKI_00300	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HEFKFHKI_00301	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HEFKFHKI_00302	1.2e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
HEFKFHKI_00303	2.08e-124	-	-	-	-	-	-	-	-
HEFKFHKI_00304	3.7e-11	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEFKFHKI_00305	1.54e-05	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEFKFHKI_00306	1.3e-27	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HEFKFHKI_00307	3.01e-63	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_00309	1.94e-64	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HEFKFHKI_00312	4.26e-106	-	-	-	F	-	-	-	Deoxynucleoside kinase
HEFKFHKI_00313	1.11e-53	-	-	-	-	-	-	-	-
HEFKFHKI_00317	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEFKFHKI_00318	1.94e-09	-	-	-	S	-	-	-	electron carrier activity
HEFKFHKI_00321	5.16e-19	-	-	-	S	-	-	-	HNH endonuclease
HEFKFHKI_00325	4.83e-64	-	-	-	-	-	-	-	-
HEFKFHKI_00326	7.17e-60	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HEFKFHKI_00327	7.93e-172	-	-	-	M	-	-	-	Prophage endopeptidase tail
HEFKFHKI_00329	5.11e-260	-	-	-	L	-	-	-	Transposase
HEFKFHKI_00330	3.57e-152	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HEFKFHKI_00331	6.13e-100	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HEFKFHKI_00332	6.9e-134	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HEFKFHKI_00333	2.36e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HEFKFHKI_00334	2.97e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEFKFHKI_00335	1.33e-66	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HEFKFHKI_00336	3.31e-206	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HEFKFHKI_00337	1.38e-75	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HEFKFHKI_00338	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HEFKFHKI_00339	5.28e-105	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HEFKFHKI_00340	1.57e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEFKFHKI_00341	4.96e-307	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HEFKFHKI_00342	5.43e-185	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HEFKFHKI_00343	9.89e-43	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HEFKFHKI_00344	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HEFKFHKI_00345	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEFKFHKI_00346	6.96e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEFKFHKI_00347	9.18e-83	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
HEFKFHKI_00348	3.51e-142	yvrI	-	-	K	ko:K03091,ko:K03093	-	ko00000,ko03021	sigma factor activity
HEFKFHKI_00349	2.07e-263	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HEFKFHKI_00350	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HEFKFHKI_00351	1.81e-146	-	-	-	T	ko:K10716	-	ko00000,ko02000	Ion transport 2 domain protein
HEFKFHKI_00352	4.12e-227	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HEFKFHKI_00354	0.0	-	-	-	L	-	-	-	PLD-like domain
HEFKFHKI_00355	1.27e-82	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HEFKFHKI_00356	1.78e-210	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HEFKFHKI_00357	1.04e-149	-	-	-	L	-	-	-	Type I restriction modification DNA specificity domain
HEFKFHKI_00358	1.02e-228	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_00359	5.82e-73	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HEFKFHKI_00360	2.77e-51	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HEFKFHKI_00361	1.29e-59	-	-	-	S	ko:K07334	-	ko00000,ko02048	RelE-like toxin of type II toxin-antitoxin system HigB
HEFKFHKI_00362	1.26e-64	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HEFKFHKI_00363	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HEFKFHKI_00364	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HEFKFHKI_00365	1.48e-178	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HEFKFHKI_00366	2.75e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HEFKFHKI_00367	1.26e-60	-	-	-	-	-	-	-	-
HEFKFHKI_00368	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
HEFKFHKI_00369	4.45e-47	-	-	-	-	-	-	-	-
HEFKFHKI_00370	5.41e-73	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HEFKFHKI_00371	1.31e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HEFKFHKI_00373	1.21e-92	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HEFKFHKI_00377	8.5e-266	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEFKFHKI_00378	4.96e-73	-	-	-	-	-	-	-	-
HEFKFHKI_00382	1.98e-44	-	-	-	-	-	-	-	-
HEFKFHKI_00386	2.12e-40	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HEFKFHKI_00387	6.7e-210	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HEFKFHKI_00389	2.57e-32	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HEFKFHKI_00390	4.62e-300	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEFKFHKI_00391	0.0	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HEFKFHKI_00392	3.07e-89	-	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_00393	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_00394	1.4e-146	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HEFKFHKI_00395	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HEFKFHKI_00396	1.4e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HEFKFHKI_00397	3.01e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEFKFHKI_00398	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEFKFHKI_00399	4.72e-240	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEFKFHKI_00400	3.65e-67	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HEFKFHKI_00401	1.88e-68	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HEFKFHKI_00402	1.38e-226	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEFKFHKI_00403	4.38e-205	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEFKFHKI_00404	5.93e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HEFKFHKI_00405	1.08e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEFKFHKI_00406	4.49e-178	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
HEFKFHKI_00407	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
HEFKFHKI_00408	2.37e-216	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HEFKFHKI_00409	2.04e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEFKFHKI_00410	9.41e-278	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HEFKFHKI_00411	5.33e-211	-	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	PFAM extracellular solute-binding protein, family 3
HEFKFHKI_00412	5.98e-116	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HEFKFHKI_00413	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEFKFHKI_00414	3.57e-150	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HEFKFHKI_00415	2.12e-19	-	-	-	-	-	-	-	-
HEFKFHKI_00416	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEFKFHKI_00417	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEFKFHKI_00418	9.18e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HEFKFHKI_00419	3.42e-209	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HEFKFHKI_00420	6.97e-240	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HEFKFHKI_00421	1.37e-218	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HEFKFHKI_00423	1.83e-21	-	-	-	-	-	-	-	-
HEFKFHKI_00424	1.65e-199	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HEFKFHKI_00425	7.29e-58	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HEFKFHKI_00426	4.72e-134	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEFKFHKI_00427	1.6e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HEFKFHKI_00428	2.7e-47	ynzC	-	-	S	-	-	-	UPF0291 protein
HEFKFHKI_00429	2.52e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEFKFHKI_00433	1.77e-93	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEFKFHKI_00434	6.83e-101	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEFKFHKI_00435	2.02e-75	-	-	-	L	-	-	-	Helix-turn-helix domain
HEFKFHKI_00436	6.57e-163	-	-	-	L	-	-	-	Helix-turn-helix domain
HEFKFHKI_00439	2.79e-145	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HEFKFHKI_00447	1.7e-182	-	-	-	-	-	-	-	-
HEFKFHKI_00448	4.29e-18	-	-	-	-	-	-	-	-
HEFKFHKI_00449	2.44e-99	-	-	-	-	-	-	-	-
HEFKFHKI_00450	5.09e-107	-	-	-	-	-	-	-	-
HEFKFHKI_00451	2.6e-14	-	-	-	K	-	-	-	Peptidase S24-like
HEFKFHKI_00452	1.21e-30	-	-	-	K	-	-	-	Peptidase S24-like
HEFKFHKI_00453	0.0	pepD3	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEFKFHKI_00454	3.16e-258	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HEFKFHKI_00455	3.37e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEFKFHKI_00456	3.36e-77	-	-	-	-	-	-	-	-
HEFKFHKI_00457	2.15e-234	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HEFKFHKI_00458	3.5e-167	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEFKFHKI_00459	2.38e-72	-	-	-	-	-	-	-	-
HEFKFHKI_00460	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEFKFHKI_00461	1.54e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEFKFHKI_00462	2.65e-214	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HEFKFHKI_00463	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEFKFHKI_00464	1.89e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_00465	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00466	1e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HEFKFHKI_00467	1.58e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HEFKFHKI_00468	9.82e-234	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEFKFHKI_00469	1.46e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEFKFHKI_00470	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HEFKFHKI_00471	3.59e-121	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HEFKFHKI_00472	1.49e-227	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEFKFHKI_00473	6.39e-235	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HEFKFHKI_00474	1.55e-109	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEFKFHKI_00475	1.8e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HEFKFHKI_00476	2.66e-219	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEFKFHKI_00477	1.24e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HEFKFHKI_00478	2.14e-234	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HEFKFHKI_00479	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HEFKFHKI_00480	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEFKFHKI_00481	5.12e-266	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEFKFHKI_00482	1.64e-142	-	-	-	-	-	-	-	-
HEFKFHKI_00483	1.97e-90	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEFKFHKI_00484	2.89e-121	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEFKFHKI_00485	3.94e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HEFKFHKI_00486	9.25e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEFKFHKI_00504	1.22e-208	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HEFKFHKI_00505	4.03e-133	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEFKFHKI_00506	4.18e-161	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HEFKFHKI_00507	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HEFKFHKI_00508	2.13e-142	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HEFKFHKI_00509	1.04e-114	-	-	-	-	-	-	-	-
HEFKFHKI_00510	1.61e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HEFKFHKI_00511	5.21e-275	yttB	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_00512	1.03e-146	-	-	-	-	-	-	-	-
HEFKFHKI_00513	2.6e-33	-	-	-	-	-	-	-	-
HEFKFHKI_00514	2.66e-221	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HEFKFHKI_00515	0.0	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEFKFHKI_00516	1.36e-66	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HEFKFHKI_00517	9.71e-50	-	-	-	-	-	-	-	-
HEFKFHKI_00518	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_00519	2.58e-156	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_00520	2.5e-236	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00521	5.75e-117	-	-	-	K	-	-	-	transcriptional regulator (TetR family)
HEFKFHKI_00522	9.96e-244	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HEFKFHKI_00523	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEFKFHKI_00524	2.09e-86	-	-	-	-	-	-	-	-
HEFKFHKI_00525	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEFKFHKI_00527	2.99e-289	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HEFKFHKI_00528	1.24e-244	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HEFKFHKI_00529	9.08e-317	-	-	-	E	ko:K03294	-	ko00000	amino acid
HEFKFHKI_00530	1.46e-236	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEFKFHKI_00532	2.33e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HEFKFHKI_00533	9.7e-06	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HEFKFHKI_00534	2.61e-283	-	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HEFKFHKI_00535	4.93e-97	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
HEFKFHKI_00536	6.11e-44	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
HEFKFHKI_00538	8.31e-175	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HEFKFHKI_00543	4.39e-94	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HEFKFHKI_00544	2.1e-16	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HEFKFHKI_00545	2.1e-16	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HEFKFHKI_00546	8.47e-08	-	-	-	S	-	-	-	Cytochrome B5
HEFKFHKI_00547	5.47e-55	-	-	-	S	-	-	-	Cytochrome B5
HEFKFHKI_00548	2.45e-110	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HEFKFHKI_00549	9e-72	-	-	-	-	-	-	-	-
HEFKFHKI_00550	1.25e-147	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HEFKFHKI_00551	6.66e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEFKFHKI_00552	1.97e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEFKFHKI_00553	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEFKFHKI_00554	1.81e-225	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEFKFHKI_00555	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEFKFHKI_00556	5.19e-169	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HEFKFHKI_00557	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEFKFHKI_00558	1.59e-213	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEFKFHKI_00559	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HEFKFHKI_00560	6.95e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HEFKFHKI_00561	1.1e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HEFKFHKI_00562	1.05e-77	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HEFKFHKI_00563	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HEFKFHKI_00564	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEFKFHKI_00565	1.41e-242	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEFKFHKI_00566	1.81e-50	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEFKFHKI_00567	1.57e-168	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEFKFHKI_00568	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HEFKFHKI_00569	4.22e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEFKFHKI_00570	4.23e-76	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEFKFHKI_00571	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEFKFHKI_00572	1.21e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HEFKFHKI_00573	3.74e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HEFKFHKI_00574	1.86e-119	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEFKFHKI_00575	5.46e-183	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HEFKFHKI_00576	0.0	-	-	-	E	ko:K03294	-	ko00000	amino acid
HEFKFHKI_00577	3.03e-83	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEFKFHKI_00581	2.8e-81	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HEFKFHKI_00585	1.85e-23	-	-	-	-	-	-	-	-
HEFKFHKI_00586	1.19e-46	-	-	-	A	ko:K12092	ko05120,map05120	ko00000,ko00001,ko00002,ko02044	chlorophyll binding
HEFKFHKI_00593	8.86e-79	-	-	-	-	-	-	-	-
HEFKFHKI_00595	7.37e-62	-	-	-	-	-	-	-	-
HEFKFHKI_00597	1.68e-211	-	-	-	S	-	-	-	Terminase-like family
HEFKFHKI_00604	1.7e-38	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
HEFKFHKI_00615	1.41e-79	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HEFKFHKI_00618	1.99e-53	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEFKFHKI_00619	1.45e-55	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEFKFHKI_00620	2.64e-103	-	-	-	L	ko:K07482	-	ko00000	transposase and inactivated derivatives, IS30 family
HEFKFHKI_00621	2.75e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEFKFHKI_00622	1.78e-204	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HEFKFHKI_00623	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HEFKFHKI_00624	1.05e-175	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_00625	7.79e-236	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HEFKFHKI_00626	6.91e-164	XK27_10500	-	-	K	-	-	-	response regulator
HEFKFHKI_00627	1.3e-204	yvgN	-	-	S	-	-	-	Aldo keto reductase
HEFKFHKI_00628	5.87e-177	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HEFKFHKI_00629	8.19e-108	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEFKFHKI_00630	2.72e-262	-	-	-	-	-	-	-	-
HEFKFHKI_00631	4.33e-69	-	-	-	-	-	-	-	-
HEFKFHKI_00632	1.21e-48	-	-	-	-	-	-	-	-
HEFKFHKI_00633	1.65e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HEFKFHKI_00634	4.87e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HEFKFHKI_00635	7.24e-239	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEFKFHKI_00636	3.09e-289	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEFKFHKI_00637	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HEFKFHKI_00638	2.92e-233	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEFKFHKI_00639	3.48e-131	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
HEFKFHKI_00640	5.61e-292	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEFKFHKI_00641	3.83e-104	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HEFKFHKI_00642	2.71e-103	usp5	-	-	T	-	-	-	universal stress protein
HEFKFHKI_00643	5.13e-46	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HEFKFHKI_00644	1.36e-99	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
HEFKFHKI_00645	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HEFKFHKI_00646	4.48e-55	-	-	-	-	-	-	-	-
HEFKFHKI_00647	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEFKFHKI_00648	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEFKFHKI_00649	3.75e-246	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HEFKFHKI_00650	2.59e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HEFKFHKI_00655	1.53e-14	-	-	-	S	-	-	-	ORF6C domain
HEFKFHKI_00656	3.63e-82	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEFKFHKI_00657	1.04e-115	-	-	-	-	-	-	-	-
HEFKFHKI_00659	1.39e-169	-	-	-	F	-	-	-	NUDIX domain
HEFKFHKI_00660	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEFKFHKI_00661	3.53e-135	pncA	-	-	Q	-	-	-	Isochorismatase family
HEFKFHKI_00662	2.34e-266	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HEFKFHKI_00663	0.0	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HEFKFHKI_00664	1.72e-212	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
HEFKFHKI_00665	1.07e-52	hxlR	-	-	K	-	-	-	regulation of RNA biosynthetic process
HEFKFHKI_00666	1.49e-309	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HEFKFHKI_00667	1.89e-171	-	-	-	IQ	-	-	-	dehydrogenase reductase
HEFKFHKI_00668	2.33e-51	-	-	-	-	-	-	-	-
HEFKFHKI_00669	1.39e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HEFKFHKI_00670	2.3e-52	-	-	-	S	-	-	-	Cytochrome b5-like Heme/Steroid binding domain
HEFKFHKI_00671	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HEFKFHKI_00672	2.8e-232	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEFKFHKI_00674	2.5e-132	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HEFKFHKI_00675	1.26e-82	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HEFKFHKI_00676	6.12e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEFKFHKI_00678	3.04e-233	ydhF	-	-	S	-	-	-	Aldo keto reductase
HEFKFHKI_00679	7.26e-107	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HEFKFHKI_00680	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HEFKFHKI_00682	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HEFKFHKI_00683	2.84e-73	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HEFKFHKI_00684	9.01e-164	-	-	-	-	-	-	-	-
HEFKFHKI_00685	3e-167	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HEFKFHKI_00686	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HEFKFHKI_00687	6.49e-288	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Metalloenzyme superfamily
HEFKFHKI_00688	4.44e-11	-	-	-	-	-	-	-	-
HEFKFHKI_00689	6.39e-198	-	-	-	GM	-	-	-	NAD(P)H-binding
HEFKFHKI_00690	1.11e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_00691	5.3e-209	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HEFKFHKI_00692	2.35e-139	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00693	4.82e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_00694	1.96e-138	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HEFKFHKI_00695	1.05e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HEFKFHKI_00696	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HEFKFHKI_00697	3.17e-240	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HEFKFHKI_00698	2.88e-09	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HEFKFHKI_00699	5.25e-140	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00700	1.04e-245	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEFKFHKI_00701	1.45e-198	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEFKFHKI_00702	5.14e-217	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HEFKFHKI_00703	1.63e-278	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HEFKFHKI_00704	9.57e-52	-	1.3.5.4	-	S	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FMN binding
HEFKFHKI_00705	8.11e-152	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEFKFHKI_00706	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HEFKFHKI_00707	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEFKFHKI_00709	1.57e-260	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEFKFHKI_00710	0.0	-	-	-	L	-	-	-	DNA helicase
HEFKFHKI_00711	1.17e-105	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HEFKFHKI_00712	6.68e-238	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	Belongs to the N(4) N(6)-methyltransferase family
HEFKFHKI_00713	1.3e-241	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HEFKFHKI_00714	4.38e-215	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEFKFHKI_00715	3.28e-296	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HEFKFHKI_00716	1.33e-228	-	-	-	-	-	-	-	-
HEFKFHKI_00717	1.51e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HEFKFHKI_00719	7.86e-207	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HEFKFHKI_00720	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEFKFHKI_00721	1.77e-198	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HEFKFHKI_00722	1.04e-128	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEFKFHKI_00723	3.58e-206	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEFKFHKI_00724	2.74e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HEFKFHKI_00725	1.71e-206	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEFKFHKI_00726	8.21e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HEFKFHKI_00727	3.28e-156	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEFKFHKI_00728	5.02e-165	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HEFKFHKI_00729	2.09e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HEFKFHKI_00730	4.57e-316	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEFKFHKI_00731	3.53e-229	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEFKFHKI_00732	8.69e-98	-	-	-	-	-	-	-	-
HEFKFHKI_00733	8.05e-259	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HEFKFHKI_00734	1.19e-31	-	-	-	-	-	-	-	-
HEFKFHKI_00735	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HEFKFHKI_00736	0.0	-	-	-	L	-	-	-	PFAM plasmid pRiA4b ORF-3 family protein
HEFKFHKI_00737	8.12e-265	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HEFKFHKI_00738	8.22e-144	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEFKFHKI_00739	1.3e-206	mleR	-	-	K	-	-	-	LysR family
HEFKFHKI_00740	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HEFKFHKI_00741	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEFKFHKI_00742	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HEFKFHKI_00743	1.85e-163	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEFKFHKI_00744	1.01e-214	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HEFKFHKI_00745	2.38e-155	citR	-	-	K	-	-	-	sugar-binding domain protein
HEFKFHKI_00746	1.15e-223	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HEFKFHKI_00747	9.38e-188	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HEFKFHKI_00748	2.56e-56	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HEFKFHKI_00749	3.29e-204	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HEFKFHKI_00750	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HEFKFHKI_00751	1.56e-193	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HEFKFHKI_00752	1.03e-142	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HEFKFHKI_00753	7.21e-205	-	-	-	K	-	-	-	LysR family
HEFKFHKI_00754	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HEFKFHKI_00755	7.76e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HEFKFHKI_00756	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_00757	6.72e-242	-	-	-	I	-	-	-	Alpha beta
HEFKFHKI_00758	5.59e-134	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HEFKFHKI_00759	1.23e-40	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HEFKFHKI_00764	4.87e-28	-	-	-	N	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HEFKFHKI_00765	1.44e-59	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HEFKFHKI_00766	4.87e-58	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HEFKFHKI_00767	3.78e-174	-	-	-	S	-	-	-	Pfam:Terminase_3C
HEFKFHKI_00768	7.83e-05	-	-	-	S	-	-	-	HNH endonuclease
HEFKFHKI_00769	1.52e-166	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HEFKFHKI_00770	9.3e-118	-	-	-	S	-	-	-	Phage minor capsid protein 2
HEFKFHKI_00771	3.62e-26	-	-	-	S	-	-	-	Phage minor structural protein GP20
HEFKFHKI_00772	1.12e-130	-	-	-	-	-	-	-	-
HEFKFHKI_00774	8.79e-38	-	-	-	S	-	-	-	Minor capsid protein
HEFKFHKI_00776	1.18e-15	-	-	-	S	-	-	-	Minor capsid protein from bacteriophage
HEFKFHKI_00777	3.44e-51	-	-	-	N	-	-	-	domain, Protein
HEFKFHKI_00779	1.66e-46	-	-	-	S	-	-	-	Bacteriophage Gp15 protein
HEFKFHKI_00780	4.41e-126	-	-	-	S	-	-	-	peptidoglycan catabolic process
HEFKFHKI_00782	5.97e-29	-	-	-	M	-	-	-	CHAP domain
HEFKFHKI_00785	1.49e-42	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HEFKFHKI_00786	3.67e-05	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
HEFKFHKI_00791	1.35e-39	-	-	-	-	-	-	-	-
HEFKFHKI_00792	2.32e-99	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HEFKFHKI_00793	5.57e-198	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HEFKFHKI_00794	8.76e-24	-	-	-	T	-	-	-	SpoVT / AbrB like domain
HEFKFHKI_00795	7.87e-47	-	-	-	T	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEFKFHKI_00798	3.34e-55	-	-	-	O	-	-	-	Bacterial dnaA protein
HEFKFHKI_00804	4.61e-15	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEFKFHKI_00812	7.57e-56	-	-	-	-	-	-	-	-
HEFKFHKI_00813	3.64e-56	-	-	-	DJ	-	-	-	Addiction module toxin, RelE
HEFKFHKI_00814	1.6e-23	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
HEFKFHKI_00815	8.03e-32	-	-	-	-	-	-	-	-
HEFKFHKI_00820	3.31e-16	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEFKFHKI_00821	9.24e-75	-	-	-	-	-	-	-	-
HEFKFHKI_00823	6.09e-206	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HEFKFHKI_00824	9.98e-103	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_00830	4.16e-209	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HEFKFHKI_00831	6.54e-76	-	-	-	S	-	-	-	hydrolase activity
HEFKFHKI_00834	4.53e-118	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
HEFKFHKI_00837	3.78e-139	-	-	-	L	-	-	-	Helix-hairpin-helix containing domain
HEFKFHKI_00838	1.22e-212	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
HEFKFHKI_00841	1.89e-103	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HEFKFHKI_00843	6.17e-202	-	-	-	-	-	-	-	-
HEFKFHKI_00844	3.15e-313	-	-	-	M	-	-	-	Glycosyl transferase
HEFKFHKI_00845	1.77e-286	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
HEFKFHKI_00846	4.47e-178	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HEFKFHKI_00847	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HEFKFHKI_00848	7.89e-304	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HEFKFHKI_00849	1.89e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HEFKFHKI_00850	3.62e-112	-	-	-	Q	-	-	-	Methyltransferase
HEFKFHKI_00851	1.89e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEFKFHKI_00852	4.46e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HEFKFHKI_00853	1.13e-217	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEFKFHKI_00854	8.7e-123	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HEFKFHKI_00855	2.04e-230	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HEFKFHKI_00856	1.83e-174	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEFKFHKI_00857	3.58e-217	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
HEFKFHKI_00858	1.56e-229	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HEFKFHKI_00859	0.0	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HEFKFHKI_00860	0.0	arcT	-	-	E	-	-	-	Dipeptidase
HEFKFHKI_00861	1.05e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HEFKFHKI_00862	1.14e-275	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HEFKFHKI_00863	1.35e-43	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
HEFKFHKI_00864	8.27e-180	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HEFKFHKI_00865	3.12e-291	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEFKFHKI_00866	5.36e-97	-	-	-	-	-	-	-	-
HEFKFHKI_00867	2.65e-99	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HEFKFHKI_00868	2.76e-119	-	-	-	S	-	-	-	peptidoglycan catabolic process
HEFKFHKI_00872	5.01e-10	-	-	-	-	-	-	-	-
HEFKFHKI_00876	3.06e-68	-	-	-	D	-	-	-	Phage-related minor tail protein
HEFKFHKI_00877	6.13e-92	xerH	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HEFKFHKI_00880	7.79e-16	-	-	-	S	-	-	-	Bacteriophage holin
HEFKFHKI_00882	3.08e-06	-	-	-	-	-	-	-	-
HEFKFHKI_00884	5.79e-24	-	-	-	-	-	-	-	-
HEFKFHKI_00885	1.03e-34	-	-	-	O	-	-	-	gp58-like protein
HEFKFHKI_00886	6.85e-115	-	-	-	-	-	-	-	-
HEFKFHKI_00887	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HEFKFHKI_00888	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEFKFHKI_00889	2.77e-219	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEFKFHKI_00890	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEFKFHKI_00891	5.23e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HEFKFHKI_00892	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEFKFHKI_00893	5.75e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HEFKFHKI_00894	4.31e-76	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HEFKFHKI_00895	1.01e-52	yabO	-	-	J	-	-	-	S4 domain protein
HEFKFHKI_00896	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEFKFHKI_00897	1.38e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEFKFHKI_00898	8.08e-147	-	-	-	S	-	-	-	(CBS) domain
HEFKFHKI_00899	2.06e-188	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HEFKFHKI_00900	9.6e-310	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HEFKFHKI_00901	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HEFKFHKI_00902	1.3e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HEFKFHKI_00903	2.28e-271	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEFKFHKI_00904	2.29e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEFKFHKI_00905	2.63e-08	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HEFKFHKI_00906	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEFKFHKI_00907	1.91e-301	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HEFKFHKI_00908	1e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEFKFHKI_00909	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEFKFHKI_00910	1.97e-231	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFKFHKI_00911	1.77e-299	isp	-	-	L	-	-	-	Transposase
HEFKFHKI_00912	0.0	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HEFKFHKI_00913	1.76e-122	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HEFKFHKI_00914	5.87e-51	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HEFKFHKI_00915	3.28e-193	-	-	-	-	-	-	-	-
HEFKFHKI_00916	8.66e-37	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HEFKFHKI_00917	1.27e-108	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HEFKFHKI_00918	9.27e-133	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HEFKFHKI_00919	1.46e-96	-	-	-	F	-	-	-	Nudix hydrolase
HEFKFHKI_00920	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HEFKFHKI_00921	4.84e-293	-	-	-	-	-	-	-	-
HEFKFHKI_00922	1.21e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEFKFHKI_00923	7.65e-184	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00924	2.49e-187	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00925	7.22e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEFKFHKI_00926	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEFKFHKI_00927	1.5e-226	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HEFKFHKI_00928	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HEFKFHKI_00929	4.86e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HEFKFHKI_00930	0.0	yagE	-	-	E	-	-	-	amino acid
HEFKFHKI_00931	1.57e-150	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HEFKFHKI_00932	2.84e-27	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HEFKFHKI_00933	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEFKFHKI_00934	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEFKFHKI_00935	2.61e-204	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HEFKFHKI_00936	4.93e-123	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HEFKFHKI_00937	3.3e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEFKFHKI_00938	8.38e-152	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HEFKFHKI_00939	1.59e-209	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HEFKFHKI_00940	3.01e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEFKFHKI_00941	9.23e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HEFKFHKI_00942	8.23e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HEFKFHKI_00943	2.02e-306	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEFKFHKI_00944	9.43e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HEFKFHKI_00945	6.72e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEFKFHKI_00946	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEFKFHKI_00947	2.44e-84	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEFKFHKI_00948	6.79e-91	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HEFKFHKI_00949	3.43e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HEFKFHKI_00950	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HEFKFHKI_00951	1.14e-190	yidA	-	-	S	-	-	-	hydrolase
HEFKFHKI_00957	7.78e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HEFKFHKI_00958	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HEFKFHKI_00959	8.71e-07	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HEFKFHKI_00960	2.79e-153	-	-	-	I	-	-	-	phosphatase
HEFKFHKI_00961	2.59e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HEFKFHKI_00962	7.95e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HEFKFHKI_00963	2.17e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HEFKFHKI_00964	2.32e-161	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HEFKFHKI_00965	4.04e-212	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HEFKFHKI_00966	3.11e-153	-	-	-	S	-	-	-	membrane
HEFKFHKI_00967	4.71e-142	-	-	-	S	-	-	-	VIT family
HEFKFHKI_00968	4.83e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEFKFHKI_00969	1.39e-173	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_00970	9.45e-196	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEFKFHKI_00971	5.24e-143	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00972	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HEFKFHKI_00973	8.11e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEFKFHKI_00974	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEFKFHKI_00975	8.46e-77	-	-	-	-	-	-	-	-
HEFKFHKI_00976	5.33e-98	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HEFKFHKI_00977	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HEFKFHKI_00978	6.51e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HEFKFHKI_00979	3.34e-212	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEFKFHKI_00981	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEFKFHKI_00982	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEFKFHKI_00983	3.81e-274	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEFKFHKI_00984	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HEFKFHKI_00985	2.83e-118	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEFKFHKI_00986	9.25e-247	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEFKFHKI_00987	3.09e-85	-	-	-	-	-	-	-	-
HEFKFHKI_00988	4.14e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HEFKFHKI_00989	1.48e-216	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEFKFHKI_00990	1.38e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEFKFHKI_00991	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEFKFHKI_00992	1.96e-65	ylxQ	-	-	J	-	-	-	ribosomal protein
HEFKFHKI_00993	5.93e-60	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HEFKFHKI_00994	3.54e-276	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HEFKFHKI_00995	6.36e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HEFKFHKI_00996	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEFKFHKI_00997	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEFKFHKI_00998	9.87e-300	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HEFKFHKI_00999	2.03e-178	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HEFKFHKI_01000	6.92e-184	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEFKFHKI_01001	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HEFKFHKI_01002	6.71e-102	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HEFKFHKI_01003	1.69e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HEFKFHKI_01004	3.59e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEFKFHKI_01005	9.86e-59	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEFKFHKI_01006	2.05e-282	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEFKFHKI_01007	2.71e-200	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEFKFHKI_01008	9.11e-92	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEFKFHKI_01009	2.27e-93	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HEFKFHKI_01010	6.38e-159	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HEFKFHKI_01011	6.38e-258	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HEFKFHKI_01012	5.46e-170	-	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEFKFHKI_01013	5.07e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HEFKFHKI_01014	8.76e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HEFKFHKI_01015	2.68e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HEFKFHKI_01016	1.99e-146	-	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_01019	3.61e-117	-	-	-	S	-	-	-	Protein conserved in bacteria
HEFKFHKI_01020	6.94e-238	-	-	-	-	-	-	-	-
HEFKFHKI_01021	8.42e-204	-	-	-	-	-	-	-	-
HEFKFHKI_01022	7.62e-68	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HEFKFHKI_01023	6.94e-132	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEFKFHKI_01024	1.51e-200	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEFKFHKI_01025	1.28e-18	-	-	-	-	-	-	-	-
HEFKFHKI_01026	1.31e-286	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEFKFHKI_01027	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEFKFHKI_01028	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HEFKFHKI_01029	1.06e-228	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEFKFHKI_01030	1.18e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HEFKFHKI_01031	2.67e-88	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HEFKFHKI_01032	2.51e-235	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HEFKFHKI_01033	7.07e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HEFKFHKI_01034	2.39e-147	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HEFKFHKI_01035	1.38e-131	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEFKFHKI_01036	1.53e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEFKFHKI_01037	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEFKFHKI_01038	0.0	-	-	-	S	-	-	-	membrane
HEFKFHKI_01039	4.64e-92	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HEFKFHKI_01040	6.08e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEFKFHKI_01041	2.06e-152	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HEFKFHKI_01042	6.17e-151	-	-	-	M	-	-	-	PFAM NLP P60 protein
HEFKFHKI_01043	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEFKFHKI_01044	3.66e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEFKFHKI_01045	1.13e-75	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HEFKFHKI_01046	3.75e-119	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HEFKFHKI_01047	2.71e-186	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEFKFHKI_01048	1.07e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HEFKFHKI_01049	9.55e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEFKFHKI_01050	5.74e-94	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEFKFHKI_01051	1.84e-298	-	-	-	V	-	-	-	MatE
HEFKFHKI_01052	0.0	potE	-	-	E	-	-	-	Amino Acid
HEFKFHKI_01053	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEFKFHKI_01054	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HEFKFHKI_01055	7.21e-39	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HEFKFHKI_01056	1.18e-128	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HEFKFHKI_01057	1.75e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HEFKFHKI_01058	9.84e-183	yqeM	-	-	Q	-	-	-	Methyltransferase
HEFKFHKI_01059	2.3e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEFKFHKI_01060	1.07e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HEFKFHKI_01061	4.36e-161	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEFKFHKI_01062	5.4e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HEFKFHKI_01063	1.9e-279	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HEFKFHKI_01064	1.57e-124	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HEFKFHKI_01065	5.46e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEFKFHKI_01066	1.82e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HEFKFHKI_01067	2.15e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEFKFHKI_01068	2.57e-223	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HEFKFHKI_01069	2.42e-300	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HEFKFHKI_01070	2.82e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEFKFHKI_01071	5.5e-134	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEFKFHKI_01072	3.89e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEFKFHKI_01073	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEFKFHKI_01074	5.87e-155	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HEFKFHKI_01075	2.17e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HEFKFHKI_01076	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HEFKFHKI_01077	3.43e-154	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEFKFHKI_01078	2.95e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HEFKFHKI_01079	2.27e-75	-	-	-	S	-	-	-	Small secreted protein
HEFKFHKI_01080	6.25e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEFKFHKI_01081	5.08e-237	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HEFKFHKI_01082	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEFKFHKI_01083	1.49e-272	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HEFKFHKI_01084	3.18e-167	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEFKFHKI_01087	1.27e-74	-	-	-	-	-	-	-	-
HEFKFHKI_01089	3.22e-85	-	-	-	-	-	-	-	-
HEFKFHKI_01091	6.21e-14	-	-	-	L	-	-	-	DnaD domain protein
HEFKFHKI_01099	1.32e-06	-	-	-	S	-	-	-	Helix-turn-helix domain
HEFKFHKI_01100	1.24e-11	-	-	-	S	-	-	-	Phage regulatory protein, Rha family
HEFKFHKI_01102	3.56e-31	-	-	-	S	-	-	-	Helix-turn-helix domain
HEFKFHKI_01103	5.34e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEFKFHKI_01104	2.03e-168	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_01105	7.41e-130	-	-	-	-	-	-	-	-
HEFKFHKI_01106	1.25e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEFKFHKI_01107	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HEFKFHKI_01108	8.67e-201	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEFKFHKI_01109	2.39e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEFKFHKI_01110	0.0	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEFKFHKI_01111	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEFKFHKI_01112	2.44e-20	-	-	-	-	-	-	-	-
HEFKFHKI_01113	6.69e-304	-	-	-	L	-	-	-	Integrase core domain
HEFKFHKI_01114	3.32e-21	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HEFKFHKI_01115	1.08e-221	yvgN	-	-	C	-	-	-	Aldo keto reductase
HEFKFHKI_01116	2.08e-208	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HEFKFHKI_01117	3.15e-113	-	-	-	C	-	-	-	Flavodoxin
HEFKFHKI_01118	9.07e-106	-	-	-	S	-	-	-	Cupin domain
HEFKFHKI_01119	1.35e-97	-	-	-	S	-	-	-	UPF0756 membrane protein
HEFKFHKI_01120	6.11e-311	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HEFKFHKI_01121	1.68e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HEFKFHKI_01122	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HEFKFHKI_01123	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HEFKFHKI_01124	4.15e-192	-	-	-	S	-	-	-	DUF218 domain
HEFKFHKI_01125	3.39e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEFKFHKI_01126	7.82e-80	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFKFHKI_01127	1.27e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFKFHKI_01128	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
HEFKFHKI_01129	2.9e-158	-	-	-	S	-	-	-	SNARE associated Golgi protein
HEFKFHKI_01130	3.98e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HEFKFHKI_01131	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEFKFHKI_01133	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HEFKFHKI_01134	1.78e-204	endA	-	-	V	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HEFKFHKI_01135	2.29e-130	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEFKFHKI_01136	9.83e-316	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HEFKFHKI_01137	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HEFKFHKI_01138	2.28e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEFKFHKI_01139	7.9e-214	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HEFKFHKI_01140	1.83e-137	-	-	-	M	-	-	-	LysM domain protein
HEFKFHKI_01141	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HEFKFHKI_01142	2.13e-142	-	-	-	M	-	-	-	LysM domain protein
HEFKFHKI_01143	6.19e-194	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HEFKFHKI_01144	4.87e-299	-	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HEFKFHKI_01145	2.29e-309	-	1.3.1.1	-	C	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HEFKFHKI_01146	2.42e-201	yeaE	-	-	S	-	-	-	Aldo keto
HEFKFHKI_01147	4.63e-101	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEFKFHKI_01148	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HEFKFHKI_01149	7.91e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEFKFHKI_01150	2.05e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HEFKFHKI_01151	7.03e-33	-	-	-	-	-	-	-	-
HEFKFHKI_01152	2.01e-134	-	-	-	V	-	-	-	VanZ like family
HEFKFHKI_01153	8.53e-304	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HEFKFHKI_01154	1.25e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HEFKFHKI_01155	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_01156	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEFKFHKI_01157	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEFKFHKI_01158	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEFKFHKI_01159	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEFKFHKI_01160	1.81e-315	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HEFKFHKI_01161	2.44e-147	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEFKFHKI_01162	2.55e-120	-	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase, GNAT family
HEFKFHKI_01163	1.86e-212	-	-	-	S	-	-	-	reductase
HEFKFHKI_01164	0.0	-	-	-	S	-	-	-	amidohydrolase
HEFKFHKI_01165	0.0	-	-	-	K	-	-	-	Aminotransferase class I and II
HEFKFHKI_01166	4.61e-155	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HEFKFHKI_01167	1.58e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HEFKFHKI_01168	3.18e-160	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HEFKFHKI_01170	4.91e-156	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HEFKFHKI_01171	2.81e-158	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
HEFKFHKI_01172	2.6e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HEFKFHKI_01173	5.85e-254	flp	-	-	V	-	-	-	Beta-lactamase
HEFKFHKI_01174	9.8e-75	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HEFKFHKI_01175	6.53e-118	-	-	-	J	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HEFKFHKI_01176	3.43e-27	-	-	-	L	-	-	-	Addiction module antitoxin, RelB DinJ family
HEFKFHKI_01177	1.15e-26	-	-	-	S	-	-	-	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEFKFHKI_01178	5.59e-54	-	-	-	H	-	-	-	RibD C-terminal domain
HEFKFHKI_01180	4.58e-245	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HEFKFHKI_01181	3.34e-107	-	-	-	-	-	-	-	-
HEFKFHKI_01182	6.87e-312	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HEFKFHKI_01183	3.56e-179	-	-	-	T	-	-	-	EAL domain
HEFKFHKI_01185	2.12e-105	-	-	-	L	-	-	-	Integrase
HEFKFHKI_01186	2.59e-42	-	-	-	M	-	-	-	LysM domain protein
HEFKFHKI_01187	1.92e-64	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Thymidine kinase
HEFKFHKI_01189	2.03e-45	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HEFKFHKI_01200	2.06e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF1064)
HEFKFHKI_01201	1.15e-64	-	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	ATP dependent DNA ligase domain
HEFKFHKI_01203	7.97e-263	-	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HEFKFHKI_01204	4.48e-36	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	Belongs to the helicase family. UvrD subfamily
HEFKFHKI_01205	3.55e-38	-	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	DNA primase activity
HEFKFHKI_01219	3.96e-53	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HEFKFHKI_01220	3.03e-29	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEFKFHKI_01221	3.42e-14	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HEFKFHKI_01222	3.39e-30	-	-	-	S	-	-	-	YoeB-like toxin of bacterial type II toxin-antitoxin system
HEFKFHKI_01224	1.94e-104	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_01233	2.64e-123	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
HEFKFHKI_01236	2.39e-133	-	-	-	L	-	-	-	Helix-hairpin-helix containing domain
HEFKFHKI_01239	9.98e-106	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HEFKFHKI_01241	4.64e-37	-	-	-	Q	-	-	-	pyridine nucleotide-disulphide oxidoreductase
HEFKFHKI_01242	6.71e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HEFKFHKI_01243	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEFKFHKI_01244	8.32e-226	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HEFKFHKI_01245	1.98e-278	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
HEFKFHKI_01247	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HEFKFHKI_01248	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HEFKFHKI_01249	4.36e-51	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
HEFKFHKI_01250	6.79e-183	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_01251	1.71e-59	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HEFKFHKI_01252	2.56e-79	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HEFKFHKI_01253	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
HEFKFHKI_01256	3.63e-50	-	-	-	-	-	-	-	-
HEFKFHKI_01258	1.1e-106	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HEFKFHKI_01259	1.42e-126	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEFKFHKI_01260	2.08e-218	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HEFKFHKI_01261	8.37e-231	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HEFKFHKI_01262	3.06e-28	rhaS4	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HEFKFHKI_01263	6.88e-170	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HEFKFHKI_01264	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HEFKFHKI_01265	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HEFKFHKI_01266	3.86e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
HEFKFHKI_01267	7.79e-290	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HEFKFHKI_01268	2.62e-122	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEFKFHKI_01269	1.11e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HEFKFHKI_01270	6.66e-151	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEFKFHKI_01271	1.96e-167	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEFKFHKI_01272	2.77e-220	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEFKFHKI_01273	3.19e-315	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEFKFHKI_01274	1.81e-221	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HEFKFHKI_01275	1.56e-20	-	-	-	K	-	-	-	LysR substrate binding domain
HEFKFHKI_01276	1.3e-156	-	-	-	K	ko:K09681	-	ko00000,ko03000	DNA-binding transcription factor activity
HEFKFHKI_01277	4.05e-70	-	-	-	S	-	-	-	branched-chain amino acid
HEFKFHKI_01278	6.03e-196	-	-	-	E	-	-	-	AzlC protein
HEFKFHKI_01279	4.94e-127	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEFKFHKI_01280	8.2e-224	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEFKFHKI_01281	5.17e-175	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEFKFHKI_01282	4.18e-165	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEFKFHKI_01283	1.21e-99	-	-	-	S	-	-	-	Flavodoxin
HEFKFHKI_01284	8.67e-85	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HEFKFHKI_01285	4.04e-48	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HEFKFHKI_01286	1.51e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Transporter, major facilitator family protein
HEFKFHKI_01287	3.9e-212	-	-	-	H	-	-	-	geranyltranstransferase activity
HEFKFHKI_01288	2.71e-234	-	-	-	-	-	-	-	-
HEFKFHKI_01289	2.45e-26	-	-	-	-	-	-	-	-
HEFKFHKI_01290	7.45e-150	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
HEFKFHKI_01291	1.52e-241	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
HEFKFHKI_01292	1.56e-60	-	-	-	-	-	-	-	-
HEFKFHKI_01293	2.03e-136	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEFKFHKI_01294	1.17e-110	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HEFKFHKI_01295	1.27e-290	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
HEFKFHKI_01296	4.94e-109	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HEFKFHKI_01297	2.54e-243	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HEFKFHKI_01298	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEFKFHKI_01299	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
HEFKFHKI_01300	2.97e-130	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase molybdenum cofactor assembly chaperone
HEFKFHKI_01301	9.45e-168	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
HEFKFHKI_01302	1.92e-106	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HEFKFHKI_01304	3.21e-103	-	-	-	S	-	-	-	Phage tail protein
HEFKFHKI_01305	4.2e-311	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HEFKFHKI_01306	4.12e-13	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HEFKFHKI_01307	1.52e-100	-	-	-	S	-	-	-	Phage tail tube protein
HEFKFHKI_01309	1.19e-42	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEFKFHKI_01311	3.17e-65	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEFKFHKI_01312	6.52e-254	-	-	-	S	-	-	-	Phage capsid family
HEFKFHKI_01313	1.06e-151	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HEFKFHKI_01314	1.93e-265	-	-	-	S	-	-	-	Phage portal protein
HEFKFHKI_01315	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HEFKFHKI_01316	1.05e-85	-	-	-	L	-	-	-	Phage terminase, small subunit
HEFKFHKI_01317	7.51e-93	-	-	-	L	-	-	-	HNH nucleases
HEFKFHKI_01325	1.24e-24	-	-	-	-	-	-	-	-
HEFKFHKI_01326	0.000568	cro	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HEFKFHKI_01327	1.12e-139	-	-	-	K	-	-	-	Peptidase S24-like
HEFKFHKI_01331	3.03e-13	-	-	-	M	-	-	-	LysM domain
HEFKFHKI_01332	1.07e-19	-	-	-	S	-	-	-	Domain of unknown function (DUF4393)
HEFKFHKI_01334	6.69e-301	int	-	-	L	ko:K06400	-	ko00000	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HEFKFHKI_01335	8.68e-257	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HEFKFHKI_01336	2.04e-234	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HEFKFHKI_01337	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HEFKFHKI_01338	1.89e-123	-	-	-	-	-	-	-	-
HEFKFHKI_01339	4.23e-33	-	-	-	-	-	-	-	-
HEFKFHKI_01340	8.08e-83	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HEFKFHKI_01341	7.63e-117	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HEFKFHKI_01343	9.14e-66	-	-	-	-	-	-	-	-
HEFKFHKI_01344	2.59e-89	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HEFKFHKI_01345	1.81e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HEFKFHKI_01346	2.41e-111	-	-	-	F	-	-	-	NUDIX domain
HEFKFHKI_01347	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEFKFHKI_01348	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEFKFHKI_01349	3.53e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEFKFHKI_01350	1.66e-213	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HEFKFHKI_01351	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEFKFHKI_01352	6.71e-208	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HEFKFHKI_01353	9.06e-184	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEFKFHKI_01354	1.46e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEFKFHKI_01355	1.33e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HEFKFHKI_01356	2.85e-141	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HEFKFHKI_01357	4.59e-219	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HEFKFHKI_01358	4.49e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HEFKFHKI_01359	2.59e-144	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HEFKFHKI_01360	4.1e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEFKFHKI_01361	1.26e-247	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEFKFHKI_01362	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_01363	2.55e-289	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEFKFHKI_01364	1.16e-301	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HEFKFHKI_01365	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEFKFHKI_01366	0.0	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HEFKFHKI_01367	1.49e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HEFKFHKI_01368	3.8e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HEFKFHKI_01369	3.72e-84	-	-	-	M	-	-	-	Lysin motif
HEFKFHKI_01370	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HEFKFHKI_01371	1.6e-247	-	-	-	S	-	-	-	Helix-turn-helix domain
HEFKFHKI_01372	2.65e-133	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEFKFHKI_01373	1.37e-162	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEFKFHKI_01374	1.57e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEFKFHKI_01375	2.37e-178	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEFKFHKI_01376	3.67e-86	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEFKFHKI_01377	4.23e-214	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HEFKFHKI_01378	2.27e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HEFKFHKI_01379	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HEFKFHKI_01380	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HEFKFHKI_01381	7.81e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HEFKFHKI_01382	2.15e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HEFKFHKI_01383	1.52e-200	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEFKFHKI_01384	5.03e-166	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HEFKFHKI_01385	1.24e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEFKFHKI_01386	1.36e-212	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HEFKFHKI_01387	1.56e-80	-	-	-	-	-	-	-	-
HEFKFHKI_01388	3.37e-272	yttB	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_01389	3.65e-308	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HEFKFHKI_01390	1.25e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HEFKFHKI_01391	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HEFKFHKI_01392	9.36e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEFKFHKI_01393	1.03e-114	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEFKFHKI_01394	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HEFKFHKI_01395	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEFKFHKI_01396	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEFKFHKI_01397	2.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEFKFHKI_01398	5.41e-47	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HEFKFHKI_01399	8.49e-265	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEFKFHKI_01400	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEFKFHKI_01401	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HEFKFHKI_01402	9.81e-77	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEFKFHKI_01403	2.96e-172	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEFKFHKI_01404	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HEFKFHKI_01405	7.53e-191	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HEFKFHKI_01406	1.8e-249	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HEFKFHKI_01407	1.39e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HEFKFHKI_01408	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEFKFHKI_01409	2.09e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEFKFHKI_01410	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFKFHKI_01411	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFKFHKI_01412	3.31e-263	-	-	-	-	-	-	-	-
HEFKFHKI_01413	8.34e-155	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
HEFKFHKI_01414	3.56e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEFKFHKI_01415	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEFKFHKI_01416	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEFKFHKI_01417	1.63e-35	-	-	-	-	-	-	-	-
HEFKFHKI_01418	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HEFKFHKI_01419	2.09e-154	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HEFKFHKI_01420	7.78e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HEFKFHKI_01421	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HEFKFHKI_01422	1.19e-175	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HEFKFHKI_01424	2.2e-110	lytE	-	-	M	-	-	-	Lysin motif
HEFKFHKI_01425	4.88e-194	-	-	-	S	-	-	-	Cof-like hydrolase
HEFKFHKI_01426	7.53e-104	-	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_01427	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HEFKFHKI_01428	5.17e-70	-	-	-	-	-	-	-	-
HEFKFHKI_01429	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEFKFHKI_01430	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEFKFHKI_01431	1.99e-165	ybbR	-	-	S	-	-	-	YbbR-like protein
HEFKFHKI_01432	6.61e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEFKFHKI_01433	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HEFKFHKI_01434	2.47e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEFKFHKI_01435	2.26e-214	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEFKFHKI_01436	5.42e-276	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HEFKFHKI_01437	3.82e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEFKFHKI_01438	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEFKFHKI_01439	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
HEFKFHKI_01440	2.32e-179	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HEFKFHKI_01441	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HEFKFHKI_01442	2.28e-137	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HEFKFHKI_01443	3.74e-204	yvgN	-	-	S	-	-	-	Aldo keto reductase
HEFKFHKI_01444	1.3e-265	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
HEFKFHKI_01445	1.95e-109	uspA	-	-	T	-	-	-	universal stress protein
HEFKFHKI_01446	3.61e-61	-	-	-	-	-	-	-	-
HEFKFHKI_01447	8e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HEFKFHKI_01448	3.65e-114	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEFKFHKI_01449	1.14e-27	-	-	-	-	-	-	-	-
HEFKFHKI_01450	2e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HEFKFHKI_01451	4.16e-180	-	-	-	S	-	-	-	Membrane
HEFKFHKI_01452	1.24e-182	-	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HEFKFHKI_01453	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HEFKFHKI_01454	6.74e-209	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HEFKFHKI_01455	5.67e-53	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HEFKFHKI_01456	1.8e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEFKFHKI_01457	7.98e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HEFKFHKI_01458	5.39e-292	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HEFKFHKI_01459	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEFKFHKI_01460	3.69e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HEFKFHKI_01461	9.69e-38	-	-	-	-	-	-	-	-
HEFKFHKI_01462	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HEFKFHKI_01463	1.56e-130	-	-	-	S	-	-	-	Pfam:DUF3816
HEFKFHKI_01464	9.48e-183	-	-	-	G	-	-	-	MucBP domain
HEFKFHKI_01465	1.27e-151	-	-	-	-	-	-	-	-
HEFKFHKI_01466	2.62e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_01467	7.18e-86	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HEFKFHKI_01468	3.74e-241	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEFKFHKI_01469	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEFKFHKI_01470	4.39e-297	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HEFKFHKI_01471	1.77e-230	yueF	-	-	S	-	-	-	AI-2E family transporter
HEFKFHKI_01472	2.16e-200	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HEFKFHKI_01473	5.06e-259	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HEFKFHKI_01474	1.52e-147	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HEFKFHKI_01475	1.28e-143	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HEFKFHKI_01476	2.89e-110	yvbK	-	-	K	-	-	-	GNAT family
HEFKFHKI_01477	5.22e-120	-	-	-	-	-	-	-	-
HEFKFHKI_01478	3.87e-161	pnb	-	-	C	-	-	-	nitroreductase
HEFKFHKI_01479	5.29e-109	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HEFKFHKI_01480	2.35e-165	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HEFKFHKI_01481	4.43e-100	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HEFKFHKI_01482	1.22e-218	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
HEFKFHKI_01483	4.56e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HEFKFHKI_01484	2.57e-103	-	-	-	K	-	-	-	LytTr DNA-binding domain
HEFKFHKI_01485	2.44e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEFKFHKI_01486	7.31e-27	-	-	-	-	-	-	-	-
HEFKFHKI_01487	1.59e-153	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HEFKFHKI_01488	3.32e-107	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K07000,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HEFKFHKI_01489	1.32e-255	-	-	-	S	-	-	-	Protein of unknown function (DUF3114)
HEFKFHKI_01490	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HEFKFHKI_01491	2.64e-213	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HEFKFHKI_01492	1.66e-142	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HEFKFHKI_01493	7.97e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HEFKFHKI_01494	1.31e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HEFKFHKI_01495	5.47e-297	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HEFKFHKI_01497	4.15e-118	-	-	-	L	-	-	-	Transposase
HEFKFHKI_01498	1.28e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HEFKFHKI_01499	5.45e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEFKFHKI_01500	6.64e-139	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HEFKFHKI_01501	3.61e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEFKFHKI_01502	6.7e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEFKFHKI_01503	5.72e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEFKFHKI_01504	4.36e-70	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEFKFHKI_01505	9.81e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEFKFHKI_01506	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEFKFHKI_01507	5.49e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HEFKFHKI_01508	1.1e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEFKFHKI_01509	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEFKFHKI_01510	2.58e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEFKFHKI_01511	7.42e-125	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEFKFHKI_01512	4.97e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEFKFHKI_01513	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEFKFHKI_01514	2.6e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEFKFHKI_01515	5.03e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEFKFHKI_01516	5.95e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEFKFHKI_01517	5.94e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HEFKFHKI_01518	6.05e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HEFKFHKI_01519	2.88e-306	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEFKFHKI_01520	4.52e-161	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEFKFHKI_01521	2.41e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEFKFHKI_01522	5.79e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HEFKFHKI_01523	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEFKFHKI_01524	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEFKFHKI_01525	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEFKFHKI_01526	8.08e-83	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HEFKFHKI_01527	2.21e-189	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEFKFHKI_01528	2.6e-199	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEFKFHKI_01529	5.82e-181	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEFKFHKI_01530	3.13e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEFKFHKI_01531	2.63e-53	-	-	-	-	-	-	-	-
HEFKFHKI_01532	0.0	ydaO	-	-	E	-	-	-	amino acid
HEFKFHKI_01533	0.0	-	-	-	E	-	-	-	amino acid
HEFKFHKI_01534	3.5e-112	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HEFKFHKI_01535	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEFKFHKI_01536	1.83e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEFKFHKI_01538	4.67e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEFKFHKI_01539	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HEFKFHKI_01540	2.61e-236	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEFKFHKI_01541	1.37e-292	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEFKFHKI_01542	3.05e-189	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HEFKFHKI_01543	2.29e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEFKFHKI_01544	3.8e-292	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEFKFHKI_01545	1.87e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEFKFHKI_01546	1.74e-252	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEFKFHKI_01547	3.02e-135	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HEFKFHKI_01548	1.18e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HEFKFHKI_01549	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEFKFHKI_01550	1.65e-113	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEFKFHKI_01551	7.12e-170	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HEFKFHKI_01552	1.44e-159	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HEFKFHKI_01553	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HEFKFHKI_01554	6.83e-299	-	-	-	E	-	-	-	amino acid
HEFKFHKI_01555	6.38e-180	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HEFKFHKI_01556	3.26e-309	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEFKFHKI_01557	4.21e-211	-	-	-	GK	-	-	-	ROK family
HEFKFHKI_01558	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HEFKFHKI_01559	7.46e-106	uspA3	-	-	T	-	-	-	universal stress protein
HEFKFHKI_01560	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HEFKFHKI_01561	1.78e-83	-	-	-	-	-	-	-	-
HEFKFHKI_01562	3.18e-11	-	-	-	-	-	-	-	-
HEFKFHKI_01563	1.41e-152	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HEFKFHKI_01564	7.55e-174	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEFKFHKI_01565	2.77e-270	-	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_01566	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HEFKFHKI_01567	2.92e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HEFKFHKI_01568	1.92e-204	-	-	-	-	-	-	-	-
HEFKFHKI_01569	1.3e-95	-	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_01570	1.25e-241	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HEFKFHKI_01571	6.35e-69	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HEFKFHKI_01572	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HEFKFHKI_01573	6.5e-71	-	-	-	-	-	-	-	-
HEFKFHKI_01574	2.39e-146	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HEFKFHKI_01575	1.45e-315	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_01576	5.18e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HEFKFHKI_01577	4.21e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEFKFHKI_01578	6.35e-177	-	-	-	IQ	-	-	-	KR domain
HEFKFHKI_01579	6.65e-234	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HEFKFHKI_01580	1.19e-233	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HEFKFHKI_01581	1.12e-112	-	-	-	S	-	-	-	Double zinc ribbon
HEFKFHKI_01582	9.94e-176	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HEFKFHKI_01584	6.55e-97	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HEFKFHKI_01585	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HEFKFHKI_01587	2.13e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HEFKFHKI_01588	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEFKFHKI_01589	0.0	yycH	-	-	S	-	-	-	YycH protein
HEFKFHKI_01590	6.38e-196	yycI	-	-	S	-	-	-	YycH protein
HEFKFHKI_01591	3.06e-197	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HEFKFHKI_01592	6.24e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HEFKFHKI_01593	5.79e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HEFKFHKI_01594	1.02e-232	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HEFKFHKI_01595	2.63e-115	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEFKFHKI_01597	1.56e-125	-	-	-	S	-	-	-	reductase
HEFKFHKI_01598	1.08e-288	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HEFKFHKI_01599	8.4e-200	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HEFKFHKI_01600	1.52e-192	-	-	-	E	-	-	-	Glyoxalase-like domain
HEFKFHKI_01601	2.13e-189	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEFKFHKI_01602	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEFKFHKI_01603	1.06e-202	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEFKFHKI_01604	1.69e-167	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HEFKFHKI_01605	9.04e-278	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HEFKFHKI_01607	7.63e-64	-	-	-	-	-	-	-	-
HEFKFHKI_01608	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HEFKFHKI_01611	1.37e-35	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HEFKFHKI_01612	6.86e-98	-	-	-	O	-	-	-	OsmC-like protein
HEFKFHKI_01613	5.24e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFKFHKI_01614	9.47e-281	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEFKFHKI_01615	8.68e-44	-	-	-	-	-	-	-	-
HEFKFHKI_01616	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HEFKFHKI_01618	1.22e-139	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HEFKFHKI_01619	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEFKFHKI_01620	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HEFKFHKI_01621	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HEFKFHKI_01622	9.34e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HEFKFHKI_01623	4.84e-277	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HEFKFHKI_01624	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HEFKFHKI_01625	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HEFKFHKI_01626	4.32e-155	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HEFKFHKI_01627	4.02e-71	-	-	-	-	-	-	-	-
HEFKFHKI_01628	1.48e-72	lysR	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_01629	1.64e-105	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HEFKFHKI_01630	2.62e-52	-	-	-	S	-	-	-	Alpha beta hydrolase
HEFKFHKI_01631	8e-101	-	-	-	S	-	-	-	Alpha beta hydrolase
HEFKFHKI_01632	1.2e-195	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HEFKFHKI_01633	9.3e-223	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HEFKFHKI_01634	1.17e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HEFKFHKI_01635	1.45e-214	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HEFKFHKI_01636	2.82e-235	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HEFKFHKI_01637	2.62e-184	-	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_01638	3.17e-202	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HEFKFHKI_01639	7.75e-127	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HEFKFHKI_01640	8.96e-79	-	-	-	-	-	-	-	-
HEFKFHKI_01641	8.44e-168	-	-	-	F	-	-	-	glutamine amidotransferase
HEFKFHKI_01642	9.34e-59	-	-	-	T	-	-	-	EAL domain
HEFKFHKI_01643	8.79e-107	-	-	-	T	-	-	-	EAL domain
HEFKFHKI_01644	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HEFKFHKI_01645	3.34e-107	-	-	-	-	-	-	-	-
HEFKFHKI_01646	1.64e-252	-	2.7.7.65	-	T	ko:K02488	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko00002,ko01000,ko02022	GGDEF domain
HEFKFHKI_01647	3.83e-153	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HEFKFHKI_01648	2.9e-53	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HEFKFHKI_01649	1.47e-73	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HEFKFHKI_01650	1.11e-105	-	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEFKFHKI_01651	3.88e-58	-	-	-	S	-	-	-	Glycosyltransferase family 28 C-terminal domain
HEFKFHKI_01652	7.54e-91	-	-	-	M	-	-	-	Oligosaccharide biosynthesis protein Alg14 like
HEFKFHKI_01653	1.57e-62	-	-	-	M	-	-	-	Domain of unknown function (DUF1919)
HEFKFHKI_01654	1.75e-34	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HEFKFHKI_01655	3.79e-152	-	-	-	Q	-	-	-	Polysaccharide biosynthesis protein
HEFKFHKI_01656	9.3e-05	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HEFKFHKI_01658	9.57e-97	-	-	-	-	-	-	-	-
HEFKFHKI_01659	1.1e-97	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HEFKFHKI_01660	2.83e-131	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HEFKFHKI_01661	1.55e-152	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HEFKFHKI_01662	1.69e-169	epsB	-	-	M	-	-	-	biosynthesis protein
HEFKFHKI_01663	2.29e-211	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HEFKFHKI_01664	1.77e-68	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HEFKFHKI_01666	1.75e-47	-	-	-	-	-	-	-	-
HEFKFHKI_01667	1.65e-106	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HEFKFHKI_01668	6.12e-44	-	-	-	-	-	-	-	-
HEFKFHKI_01669	5.09e-162	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEFKFHKI_01670	3.84e-60	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HEFKFHKI_01671	2.4e-231	-	-	-	-	-	-	-	-
HEFKFHKI_01672	7.69e-100	-	-	-	-	-	-	-	-
HEFKFHKI_01673	5.16e-115	-	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HEFKFHKI_01675	1.01e-69	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
HEFKFHKI_01676	0.0	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
HEFKFHKI_01677	0.0	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
HEFKFHKI_01678	6.11e-68	-	-	-	-	-	-	-	-
HEFKFHKI_01679	2.03e-182	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEFKFHKI_01680	3e-194	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEFKFHKI_01681	8.1e-153	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEFKFHKI_01682	6.12e-296	-	-	-	P	-	-	-	Chloride transporter, ClC family
HEFKFHKI_01683	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HEFKFHKI_01684	5.8e-149	-	-	-	I	-	-	-	Acid phosphatase homologues
HEFKFHKI_01685	1.2e-103	-	-	-	-	-	-	-	-
HEFKFHKI_01686	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEFKFHKI_01687	1.89e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HEFKFHKI_01688	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HEFKFHKI_01689	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEFKFHKI_01690	5.4e-162	-	-	-	L	-	-	-	Helix-turn-helix domain
HEFKFHKI_01691	8.85e-209	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HEFKFHKI_01692	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HEFKFHKI_01693	1.61e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HEFKFHKI_01694	8.64e-196	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HEFKFHKI_01695	3.3e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HEFKFHKI_01697	2.48e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEFKFHKI_01698	2.26e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HEFKFHKI_01699	4.25e-290	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HEFKFHKI_01700	8.08e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEFKFHKI_01701	6.09e-162	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HEFKFHKI_01702	3.14e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEFKFHKI_01703	2.7e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HEFKFHKI_01704	1.95e-195	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HEFKFHKI_01705	1.71e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HEFKFHKI_01706	2.8e-168	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HEFKFHKI_01707	9.42e-174	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEFKFHKI_01708	4.06e-184	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HEFKFHKI_01709	2.33e-238	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HEFKFHKI_01710	4.2e-96	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFKFHKI_01711	2e-56	-	-	-	U	-	-	-	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEFKFHKI_01712	9.18e-207	ureD	-	-	O	ko:K03190	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HEFKFHKI_01713	1.4e-145	ureG	-	-	KO	ko:K03189	-	ko00000	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HEFKFHKI_01714	1.45e-170	ureF	-	-	O	ko:K03188	-	ko00000	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HEFKFHKI_01715	3.08e-102	ureE	-	-	O	ko:K03187	-	ko00000	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HEFKFHKI_01716	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Amidohydrolase family
HEFKFHKI_01717	1.15e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease beta subunit
HEFKFHKI_01718	8.76e-63	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Urease, gamma subunit
HEFKFHKI_01719	3.59e-128	-	-	-	S	-	-	-	AmiS/UreI family transporter
HEFKFHKI_01720	3.75e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HEFKFHKI_01721	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HEFKFHKI_01722	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEFKFHKI_01723	3.9e-79	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HEFKFHKI_01724	4.1e-295	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HEFKFHKI_01725	0.0	yhaN	-	-	L	-	-	-	AAA domain
HEFKFHKI_01726	1.22e-177	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEFKFHKI_01728	1.49e-102	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HEFKFHKI_01729	1.39e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_01730	3.44e-281	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HEFKFHKI_01731	4.53e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEFKFHKI_01732	1.02e-232	-	-	-	S	-	-	-	YSIRK type signal peptide
HEFKFHKI_01733	2.88e-49	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEFKFHKI_01734	3.79e-221	tnp2	-	-	L	-	-	-	PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEFKFHKI_01735	1.75e-256	-	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HEFKFHKI_01736	2.26e-149	-	-	-	S	-	-	-	Membrane
HEFKFHKI_01737	5.45e-162	-	-	-	O	-	-	-	Zinc-dependent metalloprotease
HEFKFHKI_01738	3.82e-114	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEFKFHKI_01739	1.58e-204	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEFKFHKI_01741	7.01e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HEFKFHKI_01742	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEFKFHKI_01743	3.02e-218	-	-	-	-	-	-	-	-
HEFKFHKI_01744	5.53e-52	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEFKFHKI_01745	1.11e-263	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HEFKFHKI_01746	1.93e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HEFKFHKI_01747	6.92e-179	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEFKFHKI_01748	9.45e-126	-	-	-	K	-	-	-	acetyltransferase
HEFKFHKI_01749	6.68e-238	-	-	-	-	-	-	-	-
HEFKFHKI_01751	1.78e-182	-	-	-	G	-	-	-	Peptidase_C39 like family
HEFKFHKI_01752	6.13e-41	-	-	-	-	-	-	-	-
HEFKFHKI_01753	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HEFKFHKI_01754	4.3e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HEFKFHKI_01755	8.02e-271	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HEFKFHKI_01756	1.22e-93	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HEFKFHKI_01757	2.56e-140	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HEFKFHKI_01758	1.58e-124	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HEFKFHKI_01759	4.63e-119	cps3F	-	-	-	-	-	-	-
HEFKFHKI_01760	9.95e-58	-	-	-	M	-	-	-	biosynthesis protein
HEFKFHKI_01761	1.37e-95	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HEFKFHKI_01762	3.25e-35	cps3I	-	-	G	-	-	-	Acyltransferase family
HEFKFHKI_01764	2e-112	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HEFKFHKI_01765	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HEFKFHKI_01766	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEFKFHKI_01767	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEFKFHKI_01768	3.54e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HEFKFHKI_01769	5.9e-170	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HEFKFHKI_01770	0.0	-	-	-	P	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HEFKFHKI_01771	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_01772	5.92e-150	-	-	-	-	-	-	-	-
HEFKFHKI_01775	2.01e-206	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HEFKFHKI_01776	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HEFKFHKI_01779	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HEFKFHKI_01780	3.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEFKFHKI_01781	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HEFKFHKI_01782	2.07e-236	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HEFKFHKI_01783	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEFKFHKI_01785	2.19e-131	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HEFKFHKI_01786	3.14e-276	-	1.5.1.36	-	S	ko:K19784,ko:K22393,ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HEFKFHKI_01787	8.71e-229	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEFKFHKI_01788	0.0	-	-	-	L	-	-	-	Transposase
HEFKFHKI_01789	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEFKFHKI_01790	1.48e-247	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEFKFHKI_01791	9.72e-188	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEFKFHKI_01792	7.52e-25	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEFKFHKI_01793	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEFKFHKI_01794	7.69e-176	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEFKFHKI_01795	4.09e-146	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HEFKFHKI_01796	3.67e-177	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HEFKFHKI_01797	5.48e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEFKFHKI_01798	3.71e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HEFKFHKI_01799	1.29e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HEFKFHKI_01800	2.83e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HEFKFHKI_01801	5.48e-150	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEFKFHKI_01802	4.67e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HEFKFHKI_01803	4.92e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEFKFHKI_01804	5.87e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEFKFHKI_01805	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEFKFHKI_01806	6.21e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEFKFHKI_01807	9.33e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HEFKFHKI_01808	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEFKFHKI_01809	6.31e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEFKFHKI_01810	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HEFKFHKI_01811	6.81e-172	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HEFKFHKI_01812	2.68e-127	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HEFKFHKI_01813	2.79e-75	XK27_06915	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HEFKFHKI_01814	1.9e-61	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEFKFHKI_01816	4.83e-64	-	-	-	-	-	-	-	-
HEFKFHKI_01817	2.46e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEFKFHKI_01818	3.6e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEFKFHKI_01819	3.1e-268	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEFKFHKI_01820	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HEFKFHKI_01822	9.63e-291	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
HEFKFHKI_01823	8.31e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEFKFHKI_01824	1.39e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEFKFHKI_01825	1.1e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HEFKFHKI_01826	7.11e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEFKFHKI_01827	9.18e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEFKFHKI_01828	1.82e-175	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEFKFHKI_01829	2.16e-94	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEFKFHKI_01830	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HEFKFHKI_01831	2.54e-266	yacL	-	-	S	-	-	-	domain protein
HEFKFHKI_01832	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEFKFHKI_01833	1.02e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HEFKFHKI_01834	1.65e-66	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HEFKFHKI_01835	2.5e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEFKFHKI_01836	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HEFKFHKI_01837	3.01e-181	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HEFKFHKI_01838	1.75e-173	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_01839	3.36e-154	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEFKFHKI_01840	4.46e-276	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEFKFHKI_01841	1.27e-215	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HEFKFHKI_01842	3.04e-172	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEFKFHKI_01843	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HEFKFHKI_01844	5.72e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HEFKFHKI_01845	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HEFKFHKI_01846	1.29e-176	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HEFKFHKI_01847	4.42e-216	-	-	-	C	-	-	-	Aldo keto reductase
HEFKFHKI_01848	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
HEFKFHKI_01849	1.87e-113	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HEFKFHKI_01850	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HEFKFHKI_01851	1.2e-238	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEFKFHKI_01852	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEFKFHKI_01853	2.31e-131	-	-	-	-	-	-	-	-
HEFKFHKI_01854	4.46e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEFKFHKI_01856	5.7e-255	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HEFKFHKI_01857	1.28e-24	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HEFKFHKI_01858	4.72e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HEFKFHKI_01859	8.71e-178	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HEFKFHKI_01860	5.46e-315	-	-	-	E	-	-	-	amino acid
HEFKFHKI_01861	5.18e-109	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEFKFHKI_01862	1.18e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEFKFHKI_01863	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEFKFHKI_01864	4.3e-169	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HEFKFHKI_01865	4.5e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEFKFHKI_01866	1.98e-163	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEFKFHKI_01867	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEFKFHKI_01868	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEFKFHKI_01869	3.24e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HEFKFHKI_01870	2.37e-135	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEFKFHKI_01871	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HEFKFHKI_01872	7.07e-311	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HEFKFHKI_01873	5.27e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEFKFHKI_01874	2.88e-229	-	-	-	-	-	-	-	-
HEFKFHKI_01875	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HEFKFHKI_01876	2.03e-252	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HEFKFHKI_01877	4.39e-120	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HEFKFHKI_01878	2.17e-62	ywnA	-	-	K	-	-	-	Transcriptional regulator
HEFKFHKI_01879	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HEFKFHKI_01880	8.37e-145	-	-	-	GM	-	-	-	NAD dependent epimerase dehydratase family protein
HEFKFHKI_01881	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HEFKFHKI_01882	2.65e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEFKFHKI_01883	2.05e-294	-	-	-	-	-	-	-	-
HEFKFHKI_01884	1.85e-108	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HEFKFHKI_01885	1.41e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HEFKFHKI_01886	2.74e-69	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HEFKFHKI_01887	6.67e-158	-	-	-	GM	-	-	-	NmrA-like family
HEFKFHKI_01888	7.65e-101	-	-	-	S	ko:K02348	-	ko00000	Gnat family
HEFKFHKI_01889	2.3e-52	-	-	-	S	-	-	-	Cytochrome B5
HEFKFHKI_01890	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEFKFHKI_01891	5.67e-178	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_01892	2.25e-288	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HEFKFHKI_01893	1.69e-278	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HEFKFHKI_01894	2.47e-220	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HEFKFHKI_01895	1.08e-210	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HEFKFHKI_01896	9.71e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HEFKFHKI_01897	3.57e-198	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HEFKFHKI_01898	8.34e-180	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HEFKFHKI_01899	3.96e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HEFKFHKI_01900	8.24e-43	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HEFKFHKI_01901	6.1e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEFKFHKI_01902	6.3e-175	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HEFKFHKI_01903	8.4e-259	xerS	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_01905	1.76e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEFKFHKI_01906	2.35e-101	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HEFKFHKI_01907	4.83e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEFKFHKI_01908	2.51e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEFKFHKI_01909	2.23e-209	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HEFKFHKI_01910	7.69e-170	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HEFKFHKI_01911	1.27e-288	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEFKFHKI_01912	1.3e-99	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEFKFHKI_01913	1.38e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEFKFHKI_01914	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HEFKFHKI_01915	7.2e-185	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEFKFHKI_01916	5.87e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HEFKFHKI_01917	1.04e-172	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HEFKFHKI_01924	6.39e-73	-	-	-	-	-	-	-	-
HEFKFHKI_01925	2.23e-150	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
HEFKFHKI_01926	0.0	tdc	4.1.1.25	-	E	ko:K22330	ko00350,map00350	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HEFKFHKI_01927	4.78e-295	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Amino acid permease
HEFKFHKI_01928	1.17e-246	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HEFKFHKI_01929	2.76e-277	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEFKFHKI_01930	4.94e-251	-	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_01931	1.71e-173	-	-	-	M	-	-	-	Lysin motif
HEFKFHKI_01932	5.69e-105	-	-	-	-	-	-	-	-
HEFKFHKI_01933	1.52e-125	-	-	-	K	-	-	-	PFAM GCN5-related N-acetyltransferase
HEFKFHKI_01934	1.36e-240	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HEFKFHKI_01935	3.7e-19	-	-	-	-	-	-	-	-
HEFKFHKI_01936	3.85e-123	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HEFKFHKI_01937	2.54e-36	-	-	-	-	-	-	-	-
HEFKFHKI_01938	9.92e-53	-	-	-	S	-	-	-	Cytochrome B5
HEFKFHKI_01939	4.49e-130	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HEFKFHKI_01940	6.66e-281	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEFKFHKI_01941	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HEFKFHKI_01942	8.74e-57	-	-	-	-	-	-	-	-
HEFKFHKI_01943	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HEFKFHKI_01944	9.07e-199	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEFKFHKI_01945	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HEFKFHKI_01946	5.35e-113	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEFKFHKI_01947	9.46e-242	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEFKFHKI_01948	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HEFKFHKI_01949	5.33e-147	-	-	-	-	-	-	-	-
HEFKFHKI_01950	1.06e-234	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HEFKFHKI_01951	6.34e-180	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HEFKFHKI_01952	5.09e-148	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HEFKFHKI_01953	4.76e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEFKFHKI_01954	3.24e-272	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEFKFHKI_01955	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HEFKFHKI_01956	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEFKFHKI_01957	3.17e-260	camS	-	-	S	-	-	-	sex pheromone
HEFKFHKI_01958	1.36e-66	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEFKFHKI_01959	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEFKFHKI_01960	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEFKFHKI_01961	2.72e-237	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HEFKFHKI_01969	1.74e-291	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_01970	7.81e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
HEFKFHKI_01972	0.0	-	-	-	-	-	-	-	-
HEFKFHKI_01973	7.75e-164	-	-	-	-	-	-	-	-
HEFKFHKI_01974	3.65e-100	tnpR1	-	-	L	-	-	-	Resolvase, N terminal domain
HEFKFHKI_01977	1.19e-173	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HEFKFHKI_01978	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
HEFKFHKI_01979	6.8e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HEFKFHKI_01980	1.73e-248	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEFKFHKI_01981	1.27e-215	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEFKFHKI_01982	6.56e-252	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEFKFHKI_01983	9.39e-296	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEFKFHKI_01984	6.68e-150	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEFKFHKI_01985	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEFKFHKI_01986	2.56e-250	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HEFKFHKI_01987	4.22e-169	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HEFKFHKI_01989	1.58e-79	-	-	-	-	-	-	-	-
HEFKFHKI_01990	2.32e-20	-	-	-	-	-	-	-	-
HEFKFHKI_01991	1.02e-279	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEFKFHKI_01992	1.48e-187	-	-	-	S	-	-	-	Alpha beta hydrolase
HEFKFHKI_01993	5.74e-264	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
HEFKFHKI_01994	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEFKFHKI_01995	1.77e-56	-	-	-	-	-	-	-	-
HEFKFHKI_01996	9.13e-160	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HEFKFHKI_01997	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
HEFKFHKI_01998	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HEFKFHKI_01999	1.95e-306	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HEFKFHKI_02000	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEFKFHKI_02001	1.31e-212	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HEFKFHKI_02002	4.92e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEFKFHKI_02003	3.78e-169	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HEFKFHKI_02004	6.46e-74	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HEFKFHKI_02005	6.78e-306	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HEFKFHKI_02006	1.14e-74	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HEFKFHKI_02007	6.27e-125	-	-	-	P	-	-	-	Cadmium resistance transporter
HEFKFHKI_02008	3.96e-177	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_02009	1.18e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEFKFHKI_02010	7.76e-234	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HEFKFHKI_02011	6.32e-171	-	-	-	M	-	-	-	PFAM NLP P60 protein
HEFKFHKI_02013	3.01e-19	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
HEFKFHKI_02014	1.15e-139	-	-	-	S	-	-	-	Protein of unknown function (DUF3278)
HEFKFHKI_02017	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HEFKFHKI_02018	1.57e-190	-	-	-	S	-	-	-	Putative ABC-transporter type IV
HEFKFHKI_02019	1.79e-138	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HEFKFHKI_02020	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEFKFHKI_02021	2.81e-297	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HEFKFHKI_02022	5.51e-264	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HEFKFHKI_02023	2.48e-66	-	-	-	-	-	-	-	-
HEFKFHKI_02024	4.75e-184	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HEFKFHKI_02026	8.14e-73	-	-	-	-	-	-	-	-
HEFKFHKI_02027	2.8e-159	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HEFKFHKI_02029	1.92e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HEFKFHKI_02030	8.15e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HEFKFHKI_02031	3.49e-269	-	-	-	S	-	-	-	associated with various cellular activities
HEFKFHKI_02032	2.59e-314	-	-	-	S	-	-	-	Putative metallopeptidase domain
HEFKFHKI_02033	1.48e-64	-	-	-	-	-	-	-	-
HEFKFHKI_02034	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HEFKFHKI_02035	1.03e-146	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEFKFHKI_02036	8.53e-120	ymdB	-	-	S	-	-	-	Macro domain protein
HEFKFHKI_02037	7.66e-255	-	-	-	EGP	-	-	-	Major Facilitator
HEFKFHKI_02038	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEFKFHKI_02039	1.18e-274	-	-	-	L	-	-	-	Integrase core domain
HEFKFHKI_02040	2.35e-137	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEFKFHKI_02041	2.5e-50	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HEFKFHKI_02042	7.44e-52	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEFKFHKI_02043	2.64e-121	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEFKFHKI_02044	8.94e-98	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEFKFHKI_02045	1.87e-78	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEFKFHKI_02046	4.98e-114	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Imidazoleglycerol-phosphate dehydratase
HEFKFHKI_02047	8.92e-222	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEFKFHKI_02048	3.7e-89	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEFKFHKI_02049	7.52e-104	hisZ	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEFKFHKI_02050	5.99e-104	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HEFKFHKI_02051	1.36e-152	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEFKFHKI_02052	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HEFKFHKI_02053	1.52e-263	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEFKFHKI_02054	1.34e-186	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HEFKFHKI_02055	0.0	snf	-	-	KL	-	-	-	domain protein
HEFKFHKI_02057	1.59e-49	-	-	-	-	ko:K18829	-	ko00000,ko02048	-
HEFKFHKI_02058	2.23e-47	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	Toxin-antitoxin system, toxin component, MazF family
HEFKFHKI_02060	2.41e-24	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HEFKFHKI_02062	0.0	-	-	-	LV	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
HEFKFHKI_02063	4.13e-19	-	-	-	-	-	-	-	-
HEFKFHKI_02067	1.05e-105	-	-	-	L	-	-	-	Integrase
HEFKFHKI_02068	5.15e-86	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
HEFKFHKI_02069	0.0	-	-	-	M	-	-	-	domain protein
HEFKFHKI_02070	2.51e-83	-	-	-	-	-	-	-	-
HEFKFHKI_02071	3e-251	ampC	-	-	V	-	-	-	Beta-lactamase
HEFKFHKI_02072	1.25e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HEFKFHKI_02073	6.17e-104	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HEFKFHKI_02074	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HEFKFHKI_02075	5.4e-27	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HEFKFHKI_02076	8.15e-254	potE	-	-	U	ko:K03756,ko:K03758	-	ko00000,ko02000	Amino acid permease
HEFKFHKI_02077	1.16e-133	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEFKFHKI_02078	1.45e-197	-	-	-	S	-	-	-	Helix-turn-helix domain
HEFKFHKI_02079	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HEFKFHKI_02080	3.02e-294	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HEFKFHKI_02081	2.84e-205	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HEFKFHKI_02082	1.45e-151	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEFKFHKI_02083	3.13e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HEFKFHKI_02084	1.69e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HEFKFHKI_02085	1.28e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HEFKFHKI_02086	3.39e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HEFKFHKI_02087	3.6e-158	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HEFKFHKI_02089	1.05e-305	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HEFKFHKI_02090	1.28e-75	-	-	-	-	-	-	-	-
HEFKFHKI_02092	1.69e-117	-	-	-	-	-	-	-	-
HEFKFHKI_02093	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HEFKFHKI_02094	2.2e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
HEFKFHKI_02095	1.53e-71	-	-	-	S	-	-	-	Cupredoxin-like domain
HEFKFHKI_02096	1.04e-135	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HEFKFHKI_02097	1.92e-209	-	-	-	EG	-	-	-	EamA-like transporter family
HEFKFHKI_02098	3.24e-220	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HEFKFHKI_02099	9.21e-244	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEFKFHKI_02100	2.24e-200	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HEFKFHKI_02101	8.81e-47	-	-	-	LM	-	-	-	gp58-like protein
HEFKFHKI_02108	1.79e-43	-	-	-	S	-	-	-	Bacteriophage holin of superfamily 6 (Holin_LLH)
HEFKFHKI_02109	3.89e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HEFKFHKI_02111	8.65e-20	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HEFKFHKI_02112	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HEFKFHKI_02113	2.93e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HEFKFHKI_02114	3.8e-63	-	-	-	-	-	-	-	-
HEFKFHKI_02115	2.58e-41	-	-	-	-	-	-	-	-
HEFKFHKI_02116	5.53e-24	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEFKFHKI_02117	1.06e-48	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEFKFHKI_02118	9.78e-148	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEFKFHKI_02119	1.76e-162	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HEFKFHKI_02120	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEFKFHKI_02121	3.49e-192	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HEFKFHKI_02122	1.56e-59	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HEFKFHKI_02123	8.13e-153	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HEFKFHKI_02124	1.75e-154	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HEFKFHKI_02125	3.62e-92	-	-	-	L	-	-	-	Helix-turn-helix domain
HEFKFHKI_02126	0.0	-	-	-	L	-	-	-	PLD-like domain
HEFKFHKI_02127	1e-61	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEFKFHKI_02128	2.64e-244	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEFKFHKI_02129	1.12e-49	-	-	-	IQ	-	-	-	dehydrogenase reductase
HEFKFHKI_02137	5.13e-99	-	-	-	-	-	-	-	-
HEFKFHKI_02138	9.71e-116	-	-	-	-	-	-	-	-
HEFKFHKI_02139	7.82e-37	-	-	-	-	-	-	-	-
HEFKFHKI_02140	7.77e-196	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
HEFKFHKI_02141	7.96e-158	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEFKFHKI_02142	1.13e-132	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HEFKFHKI_02143	1.5e-91	-	-	-	-	-	-	-	-
HEFKFHKI_02144	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEFKFHKI_02145	1.24e-136	-	-	-	L	-	-	-	nuclease
HEFKFHKI_02146	4.13e-116	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
HEFKFHKI_02147	2.94e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
HEFKFHKI_02148	3.77e-246	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HEFKFHKI_02149	3.41e-169	-	-	-	H	-	-	-	Uroporphyrinogen-III synthase
HEFKFHKI_02150	9.26e-145	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HEFKFHKI_02151	5.84e-174	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HEFKFHKI_02152	9.9e-131	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobinamide kinase / cobinamide phosphate guanyltransferase
HEFKFHKI_02153	0.0	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
HEFKFHKI_02154	1.56e-229	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Delta-aminolevulinic acid dehydratase
HEFKFHKI_02155	1.78e-210	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEFKFHKI_02156	3.96e-293	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEFKFHKI_02157	6.68e-103	cysG	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Putative NAD(P)-binding
HEFKFHKI_02158	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HEFKFHKI_02159	5.9e-190	cbiO	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	part of an ABC transporter complex. Responsible for energy coupling to the transport system
HEFKFHKI_02160	3.94e-149	cbiQ	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HEFKFHKI_02161	7.35e-70	cbiN	-	-	P	ko:K02009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HEFKFHKI_02162	4.44e-171	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HEFKFHKI_02163	3.64e-160	cbiL	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HEFKFHKI_02164	7.18e-187	cbiK	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
HEFKFHKI_02165	0.0	cobA	2.1.1.107, 4.2.1.75	-	H	ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HEFKFHKI_02166	3e-171	cobK	1.3.1.106, 1.3.1.54	-	H	ko:K05895	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-6x reductase CbiJ/CobK
HEFKFHKI_02167	1.06e-170	cbiH	2.1.1.131	-	H	ko:K05934	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HEFKFHKI_02168	8.21e-246	cbiG	3.7.1.12	-	H	ko:K02189	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalamin synthesis G C-terminus
HEFKFHKI_02169	1.13e-171	cbiF	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HEFKFHKI_02170	8.27e-124	cbiT	2.1.1.196	-	H	ko:K02191	ko00860,map00860	ko00000,ko00001,ko01000	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HEFKFHKI_02171	4.92e-142	cbiE	2.1.1.289	-	H	ko:K03399	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Tetrapyrrole (Corrin/Porphyrin) Methylases
HEFKFHKI_02172	2.57e-272	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HEFKFHKI_02173	6.88e-160	cbiC	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Precorrin-8X methylmutase
HEFKFHKI_02174	3.82e-228	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HEFKFHKI_02175	0.0	cbiA	6.3.5.11, 6.3.5.9	-	F	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HEFKFHKI_02176	7.26e-266	cobD	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	Aminotransferase class I and II
HEFKFHKI_02177	1.13e-132	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
HEFKFHKI_02178	1.99e-199	nqo1	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HEFKFHKI_02179	2.54e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEFKFHKI_02180	2.69e-95	eutP	-	-	E	ko:K04029	-	ko00000	Ethanolamine utilisation - propanediol utilisation
HEFKFHKI_02181	1.64e-110	-	-	-	P	-	-	-	Cadmium resistance transporter
HEFKFHKI_02182	6.68e-156	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HEFKFHKI_02183	6.64e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Pfam:Y_phosphatase3C
HEFKFHKI_02184	3.32e-74	-	-	-	E	ko:K04031	-	ko00000	BMC
HEFKFHKI_02185	1.3e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEFKFHKI_02186	3.1e-268	pduQ	-	-	C	ko:K13921	ko00640,map00640	ko00000,ko00001	Iron-containing alcohol dehydrogenase
HEFKFHKI_02187	0.0	pduP	1.2.1.87	-	C	ko:K13922	ko00640,map00640	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HEFKFHKI_02188	1.01e-104	pduO	-	-	S	-	-	-	Haem-degrading
HEFKFHKI_02189	1.26e-137	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
HEFKFHKI_02190	1.96e-55	pduN	-	-	CQ	ko:K04028	-	ko00000	Ethanolamine utilisation protein EutN/carboxysome
HEFKFHKI_02191	3.9e-116	-	-	-	S	-	-	-	Putative propanediol utilisation
HEFKFHKI_02192	1.02e-150	pduL	2.3.1.222	-	Q	ko:K13923	ko00640,map00640	ko00000,ko00001,ko01000	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HEFKFHKI_02193	4.11e-57	pduA_2	-	-	CQ	ko:K04027	-	ko00000	BMC
HEFKFHKI_02194	3.28e-112	-	-	-	CQ	-	-	-	BMC
HEFKFHKI_02195	8.32e-79	pduH	-	-	S	-	-	-	Dehydratase medium subunit
HEFKFHKI_02196	0.0	pduG	-	-	D	-	-	-	Diol dehydratase reactivase ATPase-like domain
HEFKFHKI_02197	1.1e-106	pduE	4.2.1.28	-	Q	ko:K13920	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase small subunit
HEFKFHKI_02198	7.71e-166	pduD	4.2.1.28	-	Q	ko:K13919	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase medium subunit
HEFKFHKI_02199	0.0	pduC	4.2.1.28	-	Q	ko:K01699	ko00640,map00640	ko00000,ko00001,ko01000	Dehydratase large subunit
HEFKFHKI_02200	9.77e-170	pduB	-	-	E	-	-	-	BMC
HEFKFHKI_02201	2.72e-56	-	-	-	CQ	-	-	-	BMC
HEFKFHKI_02202	9.39e-256	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HEFKFHKI_02203	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HEFKFHKI_02204	2.07e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HEFKFHKI_02205	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HEFKFHKI_02206	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEFKFHKI_02207	6.33e-295	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEFKFHKI_02208	9.51e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HEFKFHKI_02210	0.0	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEFKFHKI_02211	3.29e-183	-	-	-	M	-	-	-	Glycosyl transferase family 2
HEFKFHKI_02212	3e-111	-	-	-	-	-	-	-	-
HEFKFHKI_02213	1.13e-35	-	-	-	-	-	-	-	-
HEFKFHKI_02215	1.39e-142	-	-	-	-	-	-	-	-
HEFKFHKI_02216	1.46e-192	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HEFKFHKI_02217	1.37e-112	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HEFKFHKI_02218	5.03e-238	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HEFKFHKI_02219	4.49e-171	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HEFKFHKI_02220	0.0	sdrF	-	-	M	ko:K14194	ko05150,map05150	ko00000,ko00001	protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HEFKFHKI_02221	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HEFKFHKI_02222	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEFKFHKI_02223	8.53e-95	-	-	-	-	-	-	-	-
HEFKFHKI_02224	1.03e-106	-	-	-	L	ko:K07491	-	ko00000	PFAM transposase IS200-family protein
HEFKFHKI_02225	7.85e-126	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
HEFKFHKI_02226	2.28e-102	-	2.7.7.60	-	H	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase
HEFKFHKI_02227	6.72e-233	-	-	-	M	-	-	-	MobA-like NTP transferase domain
HEFKFHKI_02228	3.81e-113	-	-	-	M	-	-	-	MobA-like NTP transferase domain
HEFKFHKI_02229	4.72e-212	cudT	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HEFKFHKI_02230	6.58e-254	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEFKFHKI_02231	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEFKFHKI_02232	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEFKFHKI_02233	2.59e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HEFKFHKI_02234	4.1e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEFKFHKI_02235	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEFKFHKI_02236	1.13e-266	hpk31	-	-	T	-	-	-	Histidine kinase
HEFKFHKI_02237	9.76e-161	vanR	-	-	K	-	-	-	response regulator
HEFKFHKI_02238	1.47e-265	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEFKFHKI_02239	2.28e-220	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	sugar-binding domain protein
HEFKFHKI_02240	3.27e-167	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HEFKFHKI_02241	3.48e-304	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
HEFKFHKI_02242	9.76e-300	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEFKFHKI_02243	6.58e-152	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEFKFHKI_02246	1.31e-103	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HEFKFHKI_02247	4.08e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEFKFHKI_02248	5.67e-157	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEFKFHKI_02249	2.15e-267	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HEFKFHKI_02250	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HEFKFHKI_02251	2.51e-150	yjbH	-	-	Q	-	-	-	Thioredoxin
HEFKFHKI_02252	9.06e-151	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HEFKFHKI_02253	1.52e-198	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEFKFHKI_02254	4.28e-225	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEFKFHKI_02255	8.95e-90	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HEFKFHKI_02256	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEFKFHKI_02257	1.3e-212	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEFKFHKI_02258	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEFKFHKI_02259	6.84e-121	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEFKFHKI_02260	1.07e-95	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEFKFHKI_02261	1.26e-29	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEFKFHKI_02262	4.63e-162	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HEFKFHKI_02263	5.64e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HEFKFHKI_02264	2.57e-183	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HEFKFHKI_02266	7.17e-177	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HEFKFHKI_02267	1.87e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HEFKFHKI_02268	3.64e-13	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
HEFKFHKI_02270	5.35e-184	-	-	-	-	-	-	-	-
HEFKFHKI_02271	2.64e-169	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HEFKFHKI_02272	8.59e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HEFKFHKI_02273	4.7e-103	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEFKFHKI_02274	4.96e-216	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HEFKFHKI_02275	4.15e-282	arcT	-	-	E	-	-	-	Aminotransferase
HEFKFHKI_02276	3.06e-202	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HEFKFHKI_02277	9.04e-90	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HEFKFHKI_02278	9.12e-26	potE	-	-	E	-	-	-	Amino Acid
HEFKFHKI_02279	2.32e-315	potE	-	-	E	-	-	-	Amino Acid
HEFKFHKI_02280	2.6e-201	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HEFKFHKI_02282	5.1e-45	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HEFKFHKI_02283	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEFKFHKI_02284	7.58e-165	-	-	-	F	-	-	-	NUDIX domain
HEFKFHKI_02285	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEFKFHKI_02286	5.49e-134	pncA	-	-	Q	-	-	-	Isochorismatase family
HEFKFHKI_02287	0.0	-	-	-	L	-	-	-	Recombinase
HEFKFHKI_02288	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HEFKFHKI_02289	1.03e-37	-	-	-	-	-	-	-	-
HEFKFHKI_02290	4.53e-186	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HEFKFHKI_02291	4.02e-90	-	-	-	S	-	-	-	Bacteriophage holin family
HEFKFHKI_02292	1.29e-88	-	-	-	S	-	-	-	Phage head-tail joining protein
HEFKFHKI_02293	2.17e-57	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEFKFHKI_02294	1.29e-281	-	-	-	S	-	-	-	Phage capsid family
HEFKFHKI_02295	4.66e-156	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HEFKFHKI_02296	3.93e-309	-	-	-	S	-	-	-	Phage portal protein
HEFKFHKI_02297	3.75e-199	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HEFKFHKI_02298	7.7e-158	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HEFKFHKI_02299	8.38e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
HEFKFHKI_02300	7.24e-147	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEFKFHKI_02301	9.68e-292	-	-	-	KL	-	-	-	DNA methylase
HEFKFHKI_02302	3.28e-128	-	-	-	-	-	-	-	-
HEFKFHKI_02303	8.4e-112	-	-	-	-	-	-	-	-
HEFKFHKI_02304	0.0	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HEFKFHKI_02305	3.57e-61	-	-	-	S	-	-	-	VRR_NUC
HEFKFHKI_02306	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HEFKFHKI_02307	1.02e-89	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEFKFHKI_02308	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HEFKFHKI_02309	8.32e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HEFKFHKI_02310	1.2e-129	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HEFKFHKI_02311	6.82e-106	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HEFKFHKI_02312	1.14e-53	-	-	-	-	-	-	-	-
HEFKFHKI_02313	5.37e-31	-	-	-	-	-	-	-	-
HEFKFHKI_02314	6.64e-94	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HEFKFHKI_02315	5.31e-73	-	-	-	T	-	-	-	Nacht domain
HEFKFHKI_02316	5.29e-109	-	-	-	-	-	-	-	-
HEFKFHKI_02317	0.0	-	-	-	S	-	-	-	AAA domain
HEFKFHKI_02318	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
HEFKFHKI_02319	4.16e-139	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HEFKFHKI_02320	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HEFKFHKI_02321	2.6e-128	-	-	-	-	-	-	-	-
HEFKFHKI_02322	2.79e-61	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HEFKFHKI_02323	1.19e-314	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HEFKFHKI_02324	7.73e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEFKFHKI_02325	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEFKFHKI_02326	6.17e-192	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HEFKFHKI_02327	1.43e-47	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HEFKFHKI_02328	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HEFKFHKI_02329	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HEFKFHKI_02330	1.02e-112	-	-	-	V	-	-	-	DNA restriction-modification system
HEFKFHKI_02331	4.83e-22	-	-	-	V	-	-	-	DNA restriction-modification system
HEFKFHKI_02332	0.0	-	-	-	G	-	-	-	Major Facilitator Superfamily
HEFKFHKI_02333	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HEFKFHKI_02334	7.67e-95	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HEFKFHKI_02335	8.83e-70	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HEFKFHKI_02336	1.13e-125	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HEFKFHKI_02337	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
HEFKFHKI_02338	3.55e-214	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEFKFHKI_02339	0.0	spoIIQ	-	-	M	ko:K06386	-	ko00000	Peptidase family M23
HEFKFHKI_02340	6.93e-154	-	-	-	M	-	-	-	Bacterial sugar transferase
HEFKFHKI_02341	7.67e-223	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HEFKFHKI_02342	1.29e-187	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HEFKFHKI_02343	6.03e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HEFKFHKI_02344	6.21e-43	-	-	-	-	-	-	-	-
HEFKFHKI_02345	8.85e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HEFKFHKI_02347	2.58e-154	-	-	-	H	-	-	-	RibD C-terminal domain
HEFKFHKI_02348	5.46e-207	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HEFKFHKI_02349	5.77e-291	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HEFKFHKI_02350	6.2e-155	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HEFKFHKI_02351	2e-73	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HEFKFHKI_02352	1.15e-15	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HEFKFHKI_02353	4.8e-114	-	-	-	C	-	-	-	Flavodoxin
HEFKFHKI_02354	1.45e-31	-	-	-	S	-	-	-	sequence-specific DNA binding
HEFKFHKI_02357	3.76e-26	-	-	-	-	-	-	-	-
HEFKFHKI_02359	2.81e-129	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEFKFHKI_02361	9.17e-59	-	-	-	-	-	-	-	-
HEFKFHKI_02362	9.01e-155	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEFKFHKI_02363	1.52e-43	-	-	-	-	-	-	-	-
HEFKFHKI_02364	8.45e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEFKFHKI_02365	7.32e-124	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEFKFHKI_02366	2.21e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HEFKFHKI_02367	3.14e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEFKFHKI_02368	3.54e-184	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HEFKFHKI_02369	8.74e-235	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEFKFHKI_02370	6.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HEFKFHKI_02371	2.92e-182	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HEFKFHKI_02372	1.84e-152	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HEFKFHKI_02373	6.08e-13	-	-	-	S	-	-	-	CsbD-like
HEFKFHKI_02374	1.9e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HEFKFHKI_02375	1.24e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEFKFHKI_02376	2.73e-161	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HEFKFHKI_02377	3.83e-147	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HEFKFHKI_02378	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEFKFHKI_02379	5.2e-189	eutJ	-	-	E	ko:K04024	-	ko00000	Hsp70 protein
HEFKFHKI_02380	4.17e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEFKFHKI_02381	1.32e-52	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HEFKFHKI_02382	7.57e-206	-	-	-	-	-	-	-	-
HEFKFHKI_02383	9.91e-204	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HEFKFHKI_02384	2.39e-239	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HEFKFHKI_02385	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HEFKFHKI_02386	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HEFKFHKI_02387	9.5e-239	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEFKFHKI_02388	1.81e-108	-	-	-	-	-	-	-	-