ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
KHECPKLA_00001 3.4e-32 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
KHECPKLA_00002 5.57e-260 - - - EGP - - - Major facilitator Superfamily
KHECPKLA_00003 1.19e-136 pncA - - Q - - - Isochorismatase family
KHECPKLA_00004 0.0 eriC - - P ko:K03281 - ko00000 chloride
KHECPKLA_00005 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KHECPKLA_00006 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
KHECPKLA_00007 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KHECPKLA_00008 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KHECPKLA_00009 9.81e-201 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHECPKLA_00010 3.62e-79 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KHECPKLA_00011 6.59e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
KHECPKLA_00012 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KHECPKLA_00013 2.32e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KHECPKLA_00014 1.04e-27 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
KHECPKLA_00015 1.63e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KHECPKLA_00016 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHECPKLA_00017 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KHECPKLA_00018 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
KHECPKLA_00019 1.24e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHECPKLA_00020 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KHECPKLA_00021 2.63e-212 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KHECPKLA_00022 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
KHECPKLA_00023 9.49e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KHECPKLA_00024 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
KHECPKLA_00025 1e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
KHECPKLA_00026 3.66e-275 - - - I - - - Protein of unknown function (DUF2974)
KHECPKLA_00027 0.0 - - - - - - - -
KHECPKLA_00028 2.08e-148 - - - S ko:K07507 - ko00000,ko02000 MgtC family
KHECPKLA_00030 1.4e-120 - - - S - - - HAD hydrolase, family IA, variant
KHECPKLA_00031 4.18e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
KHECPKLA_00032 4e-91 - - - S - - - Protein of unknown function (DUF3278)
KHECPKLA_00033 9.52e-224 ydhF - - S - - - Aldo keto reductase
KHECPKLA_00035 4.82e-256 - - - S - - - Sterol carrier protein domain
KHECPKLA_00036 2.74e-170 - - - I - - - Acyltransferase
KHECPKLA_00037 4.14e-146 - - - S ko:K07118 - ko00000 NAD(P)H-binding
KHECPKLA_00038 4.47e-168 - - - S - - - Protein of unknown function (DUF975)
KHECPKLA_00039 4.17e-174 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
KHECPKLA_00040 2.31e-193 yitS - - S - - - EDD domain protein, DegV family
KHECPKLA_00041 7.84e-26 - - - - - - - -
KHECPKLA_00042 3.16e-179 - - - V - - - ABC transporter transmembrane region
KHECPKLA_00043 0.0 fusA1 - - J - - - elongation factor G
KHECPKLA_00044 1.62e-203 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
KHECPKLA_00045 1.84e-18 - - - S - - - CsbD-like
KHECPKLA_00046 1.29e-54 - - - S - - - Transglycosylase associated protein
KHECPKLA_00047 8.48e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KHECPKLA_00048 0.0 - - - L - - - Helicase C-terminal domain protein
KHECPKLA_00049 4.99e-196 - - - S - - - Alpha beta hydrolase
KHECPKLA_00050 1.49e-53 - - - - - - - -
KHECPKLA_00051 1.7e-221 ydbI - - K - - - AI-2E family transporter
KHECPKLA_00052 1.62e-294 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
KHECPKLA_00053 7.62e-270 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHECPKLA_00054 5.34e-128 - - - E - - - GDSL-like Lipase/Acylhydrolase
KHECPKLA_00055 1.71e-246 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KHECPKLA_00056 0.0 - - - S - - - domain, Protein
KHECPKLA_00057 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
KHECPKLA_00058 2.09e-215 - - - K - - - LysR substrate binding domain
KHECPKLA_00059 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KHECPKLA_00060 1.12e-302 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KHECPKLA_00061 2.67e-162 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KHECPKLA_00062 7.69e-225 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KHECPKLA_00063 2.98e-118 - - - S - - - Peptidase propeptide and YPEB domain
KHECPKLA_00064 4e-233 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
KHECPKLA_00065 1.15e-314 - - - P - - - Major Facilitator Superfamily
KHECPKLA_00066 6.4e-300 - - - P - - - Major Facilitator Superfamily
KHECPKLA_00067 5.1e-205 arbZ - - I - - - Phosphate acyltransferases
KHECPKLA_00068 1.96e-224 - - - M - - - Glycosyl transferase family 8
KHECPKLA_00069 1.56e-228 - - - M - - - Glycosyl transferase family 8
KHECPKLA_00070 6.93e-197 arbx - - M - - - Glycosyl transferase family 8
KHECPKLA_00071 1.05e-179 - - - I - - - Acyl-transferase
KHECPKLA_00073 3.03e-167 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
KHECPKLA_00074 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KHECPKLA_00075 7.14e-310 yycH - - S - - - YycH protein
KHECPKLA_00076 1.23e-185 yycI - - S - - - YycH protein
KHECPKLA_00077 9.78e-188 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
KHECPKLA_00078 2.04e-254 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
KHECPKLA_00079 3.52e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KHECPKLA_00080 4e-129 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
KHECPKLA_00081 1.88e-292 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_00082 1.18e-121 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
KHECPKLA_00083 5.23e-205 - - - K - - - helix_turn_helix, arabinose operon control protein
KHECPKLA_00084 2.25e-188 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
KHECPKLA_00085 1.8e-123 lemA - - S ko:K03744 - ko00000 LemA family
KHECPKLA_00086 6.62e-240 ysdE - - P - - - Citrate transporter
KHECPKLA_00087 1.46e-87 - - - S - - - Iron-sulphur cluster biosynthesis
KHECPKLA_00088 1.14e-23 - - - - - - - -
KHECPKLA_00089 5.77e-186 - - - - - - - -
KHECPKLA_00091 2.54e-303 - - - M - - - Glycosyl transferase
KHECPKLA_00092 1.67e-251 - - - G - - - Glycosyl hydrolases family 8
KHECPKLA_00093 1.11e-154 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
KHECPKLA_00094 3.21e-215 - - - L - - - HNH nucleases
KHECPKLA_00095 1.22e-175 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_00096 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_00097 4.64e-135 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
KHECPKLA_00098 1.23e-83 yeaO - - S - - - Protein of unknown function, DUF488
KHECPKLA_00099 2.94e-166 terC - - P - - - Integral membrane protein TerC family
KHECPKLA_00100 5.26e-123 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
KHECPKLA_00101 3.03e-168 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
KHECPKLA_00102 7.71e-104 - - - - - - - -
KHECPKLA_00103 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHECPKLA_00104 8.59e-158 yugP - - S ko:K06973 - ko00000 Putative neutral zinc metallopeptidase
KHECPKLA_00105 1.54e-219 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KHECPKLA_00106 3.14e-177 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHECPKLA_00107 1.3e-216 - - - S - - - Protein of unknown function (DUF1002)
KHECPKLA_00108 9.16e-203 - - - M - - - Glycosyltransferase like family 2
KHECPKLA_00109 2.71e-158 - - - S - - - Alpha/beta hydrolase family
KHECPKLA_00110 4.27e-77 - - - - - - - -
KHECPKLA_00111 1.28e-229 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHECPKLA_00113 1.21e-89 - - - S - - - CAAX protease self-immunity
KHECPKLA_00115 3.22e-131 - - - S - - - CAAX protease self-immunity
KHECPKLA_00116 9.22e-304 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KHECPKLA_00117 1.38e-146 - - - K - - - Bacterial regulatory proteins, tetR family
KHECPKLA_00118 4.69e-177 - - - - - - - -
KHECPKLA_00119 0.0 - - - S - - - Cysteine-rich secretory protein family
KHECPKLA_00120 3.13e-263 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
KHECPKLA_00121 8.62e-144 - - - - - - - -
KHECPKLA_00122 0.0 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
KHECPKLA_00123 4.3e-234 yibE - - S - - - overlaps another CDS with the same product name
KHECPKLA_00124 1.48e-151 yibF - - S - - - overlaps another CDS with the same product name
KHECPKLA_00125 8.09e-195 - - - I - - - alpha/beta hydrolase fold
KHECPKLA_00126 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
KHECPKLA_00127 1.27e-161 - - - K ko:K03710 - ko00000,ko03000 UTRA
KHECPKLA_00128 3.12e-271 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
KHECPKLA_00129 8.85e-290 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
KHECPKLA_00130 3.23e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KHECPKLA_00131 1.87e-196 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
KHECPKLA_00132 6.12e-190 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
KHECPKLA_00133 1.6e-89 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KHECPKLA_00134 9.03e-20 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_00135 1.46e-212 - - - S - - - zinc-ribbon domain
KHECPKLA_00136 7.8e-222 - - - - - - - -
KHECPKLA_00137 2.21e-113 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
KHECPKLA_00138 1.62e-126 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHECPKLA_00139 2.25e-156 - - - K - - - UTRA domain
KHECPKLA_00140 1.24e-191 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KHECPKLA_00141 1.66e-111 usp5 - - T - - - universal stress protein
KHECPKLA_00143 1.59e-215 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
KHECPKLA_00144 2.58e-181 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KHECPKLA_00145 2.46e-169 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHECPKLA_00146 2.05e-187 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHECPKLA_00147 6.97e-107 - - - - - - - -
KHECPKLA_00148 0.0 - - - S - - - Calcineurin-like phosphoesterase
KHECPKLA_00149 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
KHECPKLA_00150 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
KHECPKLA_00151 6.6e-83 - - - - - - - -
KHECPKLA_00152 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
KHECPKLA_00153 6.16e-177 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KHECPKLA_00154 3.55e-132 yitW - - S - - - Iron-sulfur cluster assembly protein
KHECPKLA_00155 8.07e-279 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
KHECPKLA_00156 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHECPKLA_00157 8.53e-288 yqjV - - EGP - - - Major Facilitator Superfamily
KHECPKLA_00158 1.56e-236 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
KHECPKLA_00159 3.82e-47 - - - D - - - transport
KHECPKLA_00160 3.29e-173 rpl - - K - - - Helix-turn-helix domain, rpiR family
KHECPKLA_00161 1.14e-203 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KHECPKLA_00162 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHECPKLA_00164 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KHECPKLA_00165 0.0 - - - S - - - Bacterial membrane protein, YfhO
KHECPKLA_00166 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
KHECPKLA_00167 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KHECPKLA_00168 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
KHECPKLA_00169 1.24e-94 - - - - - - - -
KHECPKLA_00170 2.8e-148 - - - - - - - -
KHECPKLA_00171 1.39e-36 - - - - - - - -
KHECPKLA_00172 3.38e-46 - - - S - - - Protein of unknown function (DUF2922)
KHECPKLA_00173 0.0 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KHECPKLA_00174 0.0 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHECPKLA_00175 3.5e-25 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHECPKLA_00176 1.04e-184 - 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
KHECPKLA_00177 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
KHECPKLA_00178 4.74e-218 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KHECPKLA_00179 1.82e-160 - - - - - - - -
KHECPKLA_00180 2.33e-175 - - - - - - - -
KHECPKLA_00181 3.69e-96 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
KHECPKLA_00182 1.11e-171 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHECPKLA_00184 2.02e-66 - - - S - - - HicB_like antitoxin of bacterial toxin-antitoxin system
KHECPKLA_00185 4.38e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHECPKLA_00186 3.78e-92 - - - S - - - GtrA-like protein
KHECPKLA_00187 1.56e-227 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
KHECPKLA_00188 6.49e-148 - - - - - - - -
KHECPKLA_00189 1.28e-194 - - - U ko:K05340 - ko00000,ko02000 sugar transport
KHECPKLA_00190 3.46e-209 - - - G - - - Aldose 1-epimerase
KHECPKLA_00191 4.09e-254 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KHECPKLA_00192 7.62e-144 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHECPKLA_00193 0.0 XK27_08315 - - M - - - Sulfatase
KHECPKLA_00194 3.08e-307 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KHECPKLA_00196 5.23e-315 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KHECPKLA_00197 1.1e-151 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHECPKLA_00198 6.12e-54 - - - K - - - sequence-specific DNA binding
KHECPKLA_00199 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
KHECPKLA_00200 1.62e-57 - - - - - - - -
KHECPKLA_00201 4.01e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHECPKLA_00202 1.47e-100 - - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
KHECPKLA_00203 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHECPKLA_00204 9.43e-102 - - - - - - - -
KHECPKLA_00205 4.62e-316 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHECPKLA_00206 7.73e-164 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
KHECPKLA_00207 2.33e-79 - - - S - - - Domain of unknown function (DUF3284)
KHECPKLA_00208 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHECPKLA_00209 1.38e-166 - - - K ko:K03492 - ko00000,ko03000 UTRA
KHECPKLA_00210 2.06e-67 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
KHECPKLA_00211 1.63e-52 - - - - - - - -
KHECPKLA_00212 3.44e-70 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KHECPKLA_00213 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHECPKLA_00214 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHECPKLA_00215 1.45e-190 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
KHECPKLA_00216 4.58e-141 - - - - - - - -
KHECPKLA_00218 4.19e-140 - - - E - - - Belongs to the SOS response-associated peptidase family
KHECPKLA_00219 1.36e-245 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHECPKLA_00220 6.82e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
KHECPKLA_00221 4.01e-125 - - - S ko:K06872 - ko00000 TPM domain
KHECPKLA_00222 3.1e-116 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
KHECPKLA_00223 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KHECPKLA_00224 2.13e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
KHECPKLA_00225 1.08e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KHECPKLA_00226 5.81e-196 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KHECPKLA_00227 2.99e-49 veg - - S - - - Biofilm formation stimulator VEG
KHECPKLA_00228 3.69e-194 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
KHECPKLA_00229 1.33e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KHECPKLA_00230 3.75e-222 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KHECPKLA_00231 2.9e-225 yvdE - - K - - - helix_turn _helix lactose operon repressor
KHECPKLA_00232 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
KHECPKLA_00233 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
KHECPKLA_00234 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
KHECPKLA_00235 2.58e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
KHECPKLA_00236 4.76e-269 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHECPKLA_00237 1.58e-293 malE - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHECPKLA_00238 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHECPKLA_00239 4.16e-199 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_00240 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
KHECPKLA_00241 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHECPKLA_00242 4.37e-92 - - - S - - - Domain of unknown function (DUF1934)
KHECPKLA_00243 3.78e-92 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KHECPKLA_00244 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KHECPKLA_00245 8.5e-304 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KHECPKLA_00246 1.79e-302 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
KHECPKLA_00247 6.51e-134 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KHECPKLA_00248 1.14e-165 - - - K - - - DNA-binding helix-turn-helix protein
KHECPKLA_00249 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
KHECPKLA_00251 5.47e-162 - - - K - - - Helix-turn-helix
KHECPKLA_00252 3.53e-14 - - - - - - - -
KHECPKLA_00253 3.2e-10 - - - - - - - -
KHECPKLA_00255 9.59e-45 - - - - - - - -
KHECPKLA_00256 6.65e-17 - - - S - - - Domain of unknown function (DUF4160)
KHECPKLA_00257 3.65e-99 - 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
KHECPKLA_00258 7.83e-66 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KHECPKLA_00259 1.97e-123 - - - - - - - -
KHECPKLA_00260 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHECPKLA_00261 9.25e-287 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KHECPKLA_00262 1.58e-91 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KHECPKLA_00263 9.5e-264 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
KHECPKLA_00264 6.52e-41 - - - - - - - -
KHECPKLA_00265 4.25e-75 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KHECPKLA_00266 9.35e-52 - - - - - - - -
KHECPKLA_00268 1.27e-307 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
KHECPKLA_00269 4.66e-196 yvgN - - C - - - Aldo keto reductase
KHECPKLA_00271 2.68e-172 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_00272 2.44e-97 - - - K - - - acetyltransferase
KHECPKLA_00273 6.55e-65 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
KHECPKLA_00274 1.29e-150 - - - S - - - Putative ABC-transporter type IV
KHECPKLA_00275 4.61e-159 - - - M - - - LysM domain protein
KHECPKLA_00276 1.45e-145 - - - M - - - LysM domain protein
KHECPKLA_00278 8.77e-77 - - - S - - - Bacterial protein of unknown function (DUF898)
KHECPKLA_00279 1.45e-235 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
KHECPKLA_00280 2.18e-73 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
KHECPKLA_00281 6.5e-168 - - - K - - - SIS domain
KHECPKLA_00282 1.58e-207 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
KHECPKLA_00285 9.41e-66 XK27_05625 - - P - - - Rhodanese Homology Domain
KHECPKLA_00286 3.97e-41 - - - - - - - -
KHECPKLA_00287 1.1e-186 - - - - - - - -
KHECPKLA_00288 5.19e-158 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
KHECPKLA_00289 2.31e-87 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
KHECPKLA_00290 4.42e-165 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KHECPKLA_00291 2.46e-250 - - - M - - - Glycosyl transferases group 1
KHECPKLA_00292 0.0 - - - M - - - Glycosyltransferase like family 2
KHECPKLA_00293 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KHECPKLA_00294 8.39e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KHECPKLA_00295 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHECPKLA_00296 0.0 - - - V - - - ABC transporter transmembrane region
KHECPKLA_00297 8.33e-186 - - - - - - - -
KHECPKLA_00298 4.11e-273 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KHECPKLA_00299 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KHECPKLA_00300 8.7e-166 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
KHECPKLA_00301 2.94e-105 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
KHECPKLA_00303 1.2e-128 - - - S - - - ECF transporter, substrate-specific component
KHECPKLA_00304 8.45e-147 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
KHECPKLA_00305 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
KHECPKLA_00306 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KHECPKLA_00307 3.81e-264 camS - - S - - - sex pheromone
KHECPKLA_00308 1.29e-64 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHECPKLA_00309 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KHECPKLA_00310 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KHECPKLA_00311 2.09e-212 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
KHECPKLA_00313 1.19e-191 - - - S - - - hydrolase
KHECPKLA_00314 2.28e-138 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
KHECPKLA_00316 1.14e-135 - - - - - - - -
KHECPKLA_00317 3.99e-149 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
KHECPKLA_00318 0.0 mutS1 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHECPKLA_00319 1.87e-88 - - - S - - - Iron-sulphur cluster biosynthesis
KHECPKLA_00320 7.23e-300 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
KHECPKLA_00321 9.99e-93 - - - K - - - Acetyltransferase (GNAT) domain
KHECPKLA_00322 1.73e-308 ynbB - - P - - - aluminum resistance
KHECPKLA_00323 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
KHECPKLA_00324 0.0 - - - E - - - Amino acid permease
KHECPKLA_00325 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
KHECPKLA_00326 1.97e-59 - - - S - - - Cupredoxin-like domain
KHECPKLA_00327 9.51e-81 - - - S - - - Cupredoxin-like domain
KHECPKLA_00328 1.78e-92 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
KHECPKLA_00329 6.21e-115 - - - - - - - -
KHECPKLA_00330 1.54e-113 - - - - - - - -
KHECPKLA_00331 1.1e-47 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
KHECPKLA_00332 2.03e-292 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KHECPKLA_00333 2.63e-59 - - - I - - - bis(5'-adenosyl)-triphosphatase activity
KHECPKLA_00334 5.76e-296 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KHECPKLA_00335 4.9e-144 - - - K - - - helix_turn_helix, mercury resistance
KHECPKLA_00337 6.61e-295 pbuG - - S ko:K06901 - ko00000,ko02000 permease
KHECPKLA_00338 2.7e-299 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
KHECPKLA_00339 1.11e-80 - - - K - - - helix_turn_helix, arabinose operon control protein
KHECPKLA_00340 1.22e-203 - - - P ko:K06610 - ko00000,ko02000 Major Facilitator Superfamily
KHECPKLA_00341 9.13e-242 ram2 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
KHECPKLA_00342 6.35e-167 - - - EGP - - - Transporter, major facilitator family protein
KHECPKLA_00343 1.17e-124 - - - GK - - - ROK family
KHECPKLA_00344 6.69e-81 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KHECPKLA_00345 1.49e-115 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KHECPKLA_00346 6.99e-140 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
KHECPKLA_00347 7.98e-47 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
KHECPKLA_00348 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
KHECPKLA_00349 5.77e-124 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHECPKLA_00350 2.31e-159 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
KHECPKLA_00351 4.16e-153 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
KHECPKLA_00352 2.09e-171 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KHECPKLA_00353 3.87e-201 - - - S - - - Aldo/keto reductase family
KHECPKLA_00354 2.21e-88 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_00355 3.1e-169 - - - S ko:K07090 - ko00000 membrane transporter protein
KHECPKLA_00356 2.53e-190 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KHECPKLA_00357 1.02e-153 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KHECPKLA_00358 2e-243 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
KHECPKLA_00359 1.13e-181 - - - S - - - Putative esterase
KHECPKLA_00360 4.74e-267 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
KHECPKLA_00361 5.49e-192 gspK - - G - - - BadF/BadG/BcrA/BcrD ATPase family
KHECPKLA_00362 0.0 pts29C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHECPKLA_00363 1.28e-231 - - - V - - - Beta-lactamase
KHECPKLA_00364 1.3e-218 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
KHECPKLA_00365 7.75e-238 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
KHECPKLA_00366 2.01e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
KHECPKLA_00367 2.64e-308 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHECPKLA_00371 9.66e-221 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
KHECPKLA_00372 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KHECPKLA_00373 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KHECPKLA_00374 3.37e-228 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
KHECPKLA_00375 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
KHECPKLA_00376 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_00377 1.93e-246 - - - S - - - DUF218 domain
KHECPKLA_00378 6.49e-134 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHECPKLA_00379 2.84e-117 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
KHECPKLA_00380 1.68e-298 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
KHECPKLA_00381 1.82e-07 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
KHECPKLA_00382 2.56e-124 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KHECPKLA_00383 9.98e-98 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KHECPKLA_00384 1.12e-146 - - - S - - - Protein of unknown function (DUF969)
KHECPKLA_00385 7.94e-199 - - - S - - - Protein of unknown function (DUF979)
KHECPKLA_00386 1.1e-150 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KHECPKLA_00387 8.25e-43 - - - - - - - -
KHECPKLA_00388 2.24e-168 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional regulator
KHECPKLA_00389 1.97e-201 mutR - - K - - - Helix-turn-helix XRE-family like proteins
KHECPKLA_00390 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
KHECPKLA_00391 3.37e-86 - - - S - - - Putative adhesin
KHECPKLA_00392 5.16e-253 napA - - P - - - Sodium/hydrogen exchanger family
KHECPKLA_00393 0.0 cadA - - P - - - P-type ATPase
KHECPKLA_00394 7.94e-109 ykuL - - S - - - (CBS) domain
KHECPKLA_00396 2.86e-50 - - - - - - - -
KHECPKLA_00398 1.8e-74 - - - - - - - -
KHECPKLA_00400 7.4e-256 - - - S - - - Membrane
KHECPKLA_00401 3.97e-59 - - - - - - - -
KHECPKLA_00402 9.7e-07 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
KHECPKLA_00403 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHECPKLA_00404 1.35e-302 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
KHECPKLA_00405 3.63e-50 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KHECPKLA_00406 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KHECPKLA_00407 5.59e-220 pbpX2 - - V - - - Beta-lactamase
KHECPKLA_00408 7.2e-273 - - - E - - - Major Facilitator Superfamily
KHECPKLA_00409 1.74e-52 - - - - - - - -
KHECPKLA_00410 1.8e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHECPKLA_00411 2.47e-198 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
KHECPKLA_00412 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
KHECPKLA_00413 0.0 - - - E ko:K03294 - ko00000 Amino Acid
KHECPKLA_00414 3.91e-217 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KHECPKLA_00415 5.16e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
KHECPKLA_00416 2.32e-197 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KHECPKLA_00417 1.17e-222 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KHECPKLA_00418 6.23e-48 - - - - - - - -
KHECPKLA_00419 1.39e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KHECPKLA_00420 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHECPKLA_00421 2.35e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KHECPKLA_00422 1.08e-145 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
KHECPKLA_00423 5.36e-290 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
KHECPKLA_00424 1.23e-150 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
KHECPKLA_00425 3.86e-261 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
KHECPKLA_00426 1.78e-308 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
KHECPKLA_00427 8.22e-248 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KHECPKLA_00428 1.48e-123 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KHECPKLA_00429 6.2e-166 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
KHECPKLA_00430 1.53e-159 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
KHECPKLA_00431 6.67e-283 ymfH - - S - - - Peptidase M16
KHECPKLA_00432 5.72e-282 ymfF - - S - - - Peptidase M16 inactive domain protein
KHECPKLA_00433 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
KHECPKLA_00434 1.13e-97 - - - S - - - Protein of unknown function (DUF1149)
KHECPKLA_00435 3.8e-135 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KHECPKLA_00436 3.46e-266 XK27_05220 - - S - - - AI-2E family transporter
KHECPKLA_00437 6.3e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
KHECPKLA_00438 2.38e-253 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
KHECPKLA_00439 1.82e-281 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
KHECPKLA_00440 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
KHECPKLA_00441 8.19e-213 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KHECPKLA_00442 2.24e-194 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KHECPKLA_00443 1.7e-146 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
KHECPKLA_00444 2.7e-138 - - - S - - - CYTH
KHECPKLA_00445 4.07e-135 yjbH - - Q - - - Thioredoxin
KHECPKLA_00446 1.81e-195 coiA - - S ko:K06198 - ko00000 Competence protein
KHECPKLA_00447 6.38e-151 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KHECPKLA_00448 5.79e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KHECPKLA_00449 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KHECPKLA_00450 7.45e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
KHECPKLA_00451 4.33e-36 - - - - - - - -
KHECPKLA_00452 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
KHECPKLA_00453 1.26e-58 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
KHECPKLA_00454 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KHECPKLA_00455 5.25e-199 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
KHECPKLA_00456 2.82e-100 - - - - - - - -
KHECPKLA_00457 2.55e-111 - - - - - - - -
KHECPKLA_00458 2.13e-145 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
KHECPKLA_00459 2.08e-176 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
KHECPKLA_00460 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHECPKLA_00461 4.09e-271 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
KHECPKLA_00462 1.85e-263 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
KHECPKLA_00463 7.02e-268 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
KHECPKLA_00464 3.89e-214 ybcH - - D ko:K06889 - ko00000 Alpha beta
KHECPKLA_00466 1.68e-186 supH - - S - - - haloacid dehalogenase-like hydrolase
KHECPKLA_00467 7.93e-254 - - - EGP - - - Major Facilitator Superfamily
KHECPKLA_00468 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
KHECPKLA_00469 4.1e-201 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KHECPKLA_00470 1.18e-26 - - - S - - - Protein of unknown function (DUF3042)
KHECPKLA_00471 4.22e-76 yqhL - - P - - - Rhodanese-like protein
KHECPKLA_00472 3.31e-47 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
KHECPKLA_00473 2.1e-150 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
KHECPKLA_00474 8.64e-106 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KHECPKLA_00475 2.42e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KHECPKLA_00476 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KHECPKLA_00477 0.0 - - - S - - - membrane
KHECPKLA_00478 7.59e-97 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KHECPKLA_00479 3.71e-260 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KHECPKLA_00480 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHECPKLA_00481 1.5e-256 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KHECPKLA_00482 4.13e-83 yodB - - K - - - Transcriptional regulator, HxlR family
KHECPKLA_00483 1.32e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHECPKLA_00484 4.07e-57 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
KHECPKLA_00485 1.06e-213 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KHECPKLA_00486 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
KHECPKLA_00487 3.11e-169 csrR - - K - - - response regulator
KHECPKLA_00488 1.61e-120 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
KHECPKLA_00489 4.45e-274 ylbM - - S - - - Belongs to the UPF0348 family
KHECPKLA_00490 7.25e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KHECPKLA_00491 6.98e-137 yqeK - - H - - - Hydrolase, HD family
KHECPKLA_00492 1.16e-153 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KHECPKLA_00493 4.38e-266 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
KHECPKLA_00494 2.42e-117 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
KHECPKLA_00495 3.09e-221 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KHECPKLA_00496 3.54e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KHECPKLA_00497 9.64e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
KHECPKLA_00498 1.29e-112 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KHECPKLA_00499 5.48e-164 - - - S ko:K01992 - ko00000,ko00002,ko02000 domain protein
KHECPKLA_00500 7.13e-207 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHECPKLA_00501 3.4e-93 - - - S - - - Protein of unknown function (DUF3021)
KHECPKLA_00502 1.88e-94 - - - K - - - LytTr DNA-binding domain
KHECPKLA_00503 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KHECPKLA_00504 1.07e-208 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
KHECPKLA_00505 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
KHECPKLA_00506 5.92e-107 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KHECPKLA_00507 1.07e-135 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KHECPKLA_00508 8.44e-199 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KHECPKLA_00509 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KHECPKLA_00510 9.77e-46 - - - EGP - - - Major Facilitator
KHECPKLA_00511 7.95e-39 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
KHECPKLA_00512 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
KHECPKLA_00513 1.04e-134 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
KHECPKLA_00514 2.76e-246 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHECPKLA_00515 1.56e-114 - - - S - - - Glycine/sarcosine/betaine reductase selenoprotein B (GRDB)
KHECPKLA_00516 2.03e-222 asnA2 3.5.1.1 - E ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
KHECPKLA_00517 3.35e-305 - - - E - - - Peptidase family M20/M25/M40
KHECPKLA_00518 2.55e-163 - - - K ko:K03710 - ko00000,ko03000 UTRA
KHECPKLA_00519 7.22e-156 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KHECPKLA_00520 4.37e-68 ytpP - - CO - - - Thioredoxin
KHECPKLA_00522 1.86e-26 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_00523 1.07e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KHECPKLA_00524 1.52e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
KHECPKLA_00525 2.11e-169 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_00526 1.67e-99 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
KHECPKLA_00527 2.65e-82 - - - - - - - -
KHECPKLA_00528 1.6e-52 - - - S - - - YtxH-like protein
KHECPKLA_00529 1.44e-201 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KHECPKLA_00530 1.3e-238 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
KHECPKLA_00531 0.0 yhaN - - L - - - AAA domain
KHECPKLA_00532 2.58e-275 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
KHECPKLA_00533 3.16e-73 yheA - - S - - - Belongs to the UPF0342 family
KHECPKLA_00534 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
KHECPKLA_00535 6.02e-189 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
KHECPKLA_00537 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
KHECPKLA_00538 2.7e-82 - - - - - - - -
KHECPKLA_00539 4.19e-112 - - - L - - - NUDIX domain
KHECPKLA_00540 1.85e-247 - - - L - - - helicase activity
KHECPKLA_00541 7.83e-67 - - - FG - - - HIT domain
KHECPKLA_00542 1.77e-62 - - - S - - - MazG-like family
KHECPKLA_00543 3.26e-76 - - - - - - - -
KHECPKLA_00544 2.02e-158 - - - - - - - -
KHECPKLA_00545 4.18e-31 - - - S - - - Fic/DOC family
KHECPKLA_00547 3.28e-122 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KHECPKLA_00548 3.38e-109 - 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 Acetyltransferase (GNAT) family
KHECPKLA_00550 4.35e-13 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHECPKLA_00551 1.12e-103 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHECPKLA_00552 7.87e-171 - - - S - - - Alpha/beta hydrolase family
KHECPKLA_00553 3.59e-13 - - - S ko:K07473 - ko00000,ko02048 RelB antitoxin
KHECPKLA_00554 2.83e-109 - - - S - - - AAA domain
KHECPKLA_00555 9.25e-86 - - - F - - - NUDIX domain
KHECPKLA_00556 1.36e-168 - - - F - - - Phosphorylase superfamily
KHECPKLA_00557 1.41e-98 - - - S - - - ASCH
KHECPKLA_00558 8.23e-34 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KHECPKLA_00559 1.46e-35 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KHECPKLA_00560 1.06e-202 rbsU - - U ko:K06216 - ko00000,ko02000 ribose uptake protein RbsU
KHECPKLA_00561 7.93e-28 ps301 - - K - - - sequence-specific DNA binding
KHECPKLA_00562 6.5e-182 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
KHECPKLA_00563 1.54e-199 - - - G - - - Transmembrane secretion effector
KHECPKLA_00564 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHECPKLA_00565 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHECPKLA_00566 3.12e-229 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KHECPKLA_00567 8.1e-257 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
KHECPKLA_00568 2.84e-215 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
KHECPKLA_00569 1.24e-205 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
KHECPKLA_00570 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KHECPKLA_00571 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
KHECPKLA_00572 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
KHECPKLA_00573 2.02e-112 ypmB - - S - - - Protein conserved in bacteria
KHECPKLA_00574 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
KHECPKLA_00575 9.3e-138 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
KHECPKLA_00576 1.51e-145 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KHECPKLA_00577 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
KHECPKLA_00578 3.29e-152 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KHECPKLA_00579 3.12e-135 ypsA - - S - - - Belongs to the UPF0398 family
KHECPKLA_00580 1.6e-124 - - - L - - - Belongs to the 'phage' integrase family
KHECPKLA_00581 5.36e-28 - - - - - - - -
KHECPKLA_00585 5.09e-11 - - - S - - - Hypothetical protein (DUF2513)
KHECPKLA_00589 1.1e-11 - - - - - - - -
KHECPKLA_00590 3.87e-49 - - - S - - - ORF6C domain
KHECPKLA_00595 1.19e-17 - - - - - - - -
KHECPKLA_00603 2.77e-53 - - - S - - - ERF superfamily
KHECPKLA_00604 1.01e-68 - - - L - - - DnaD domain protein
KHECPKLA_00605 1.12e-70 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
KHECPKLA_00607 4.55e-31 - 3.1.3.16, 3.1.4.37 - T ko:K01121,ko:K07313 - ko00000,ko01000,ko04147 RNA ligase
KHECPKLA_00610 2.49e-30 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
KHECPKLA_00611 8.09e-125 - - - L - - - Belongs to the N(4) N(6)-methyltransferase family
KHECPKLA_00612 1.87e-150 - - - K ko:K07741 - ko00000 AntA/AntB antirepressor
KHECPKLA_00617 3.24e-55 - - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KHECPKLA_00623 8.13e-79 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
KHECPKLA_00624 1.44e-26 - - - - - - - -
KHECPKLA_00638 1.4e-54 - - - S - - - Transcriptional regulator, RinA family
KHECPKLA_00641 2.04e-204 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
KHECPKLA_00643 2.87e-07 - - - - - - - -
KHECPKLA_00645 7.07e-67 - - - L - - - Phage terminase, small subunit
KHECPKLA_00646 7.45e-61 - - - L - - - Terminase
KHECPKLA_00647 6.66e-265 - - - L - - - Terminase
KHECPKLA_00648 1.01e-110 - - - L - - - DNA methylase
KHECPKLA_00650 4.03e-171 - - - S - - - portal protein
KHECPKLA_00651 6.12e-110 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
KHECPKLA_00652 1.19e-200 - - - S - - - Phage capsid family
KHECPKLA_00653 3.24e-59 - - - S - - - Phage gp6-like head-tail connector protein
KHECPKLA_00654 9.49e-40 - - - S - - - Phage head-tail joining protein
KHECPKLA_00655 4.31e-57 - - - - - - - -
KHECPKLA_00656 1.6e-62 - - - - - - - -
KHECPKLA_00657 6.91e-94 - - - S - - - Phage tail tube protein
KHECPKLA_00658 3.08e-27 - - - - - - - -
KHECPKLA_00659 0.0 - - - L - - - Phage tail tape measure protein TP901
KHECPKLA_00660 1.21e-88 - - - S - - - Phage tail protein
KHECPKLA_00661 0.0 - - - S - - - Phage minor structural protein
KHECPKLA_00663 1.03e-26 - - - - - - - -
KHECPKLA_00664 3.57e-284 - - - KQ - - - helix_turn_helix, mercury resistance
KHECPKLA_00665 5e-268 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KHECPKLA_00666 4.38e-210 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KHECPKLA_00667 3.48e-152 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KHECPKLA_00668 4.03e-239 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KHECPKLA_00669 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KHECPKLA_00670 6.16e-189 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KHECPKLA_00671 5.31e-58 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KHECPKLA_00672 4.65e-91 - - - S - - - CRISPR-associated protein (Cas_Csn2)
KHECPKLA_00674 2.59e-97 - - - S - - - HIRAN
KHECPKLA_00675 2.32e-206 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Peptidase family M48
KHECPKLA_00676 3.8e-106 - - - - - - - -
KHECPKLA_00677 1.26e-100 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
KHECPKLA_00678 5.41e-49 - - - - - - - -
KHECPKLA_00679 1.74e-86 - - - - - - - -
KHECPKLA_00680 1e-72 - - - S - - - Domain of unknown function DUF1828
KHECPKLA_00681 1.05e-121 - - - S - - - Rib/alpha-like repeat
KHECPKLA_00682 2.5e-313 yagE - - E - - - amino acid
KHECPKLA_00683 8.52e-139 - - - GM - - - NmrA-like family
KHECPKLA_00684 1.76e-132 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
KHECPKLA_00685 3.1e-217 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
KHECPKLA_00686 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KHECPKLA_00687 2.09e-303 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KHECPKLA_00688 0.0 oatA - - I - - - Acyltransferase
KHECPKLA_00689 3.12e-222 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KHECPKLA_00690 2.29e-181 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
KHECPKLA_00691 1.89e-61 - - - S - - - Lipopolysaccharide assembly protein A domain
KHECPKLA_00692 9.17e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
KHECPKLA_00693 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KHECPKLA_00694 1.57e-37 - - - S - - - Protein of unknown function (DUF2929)
KHECPKLA_00695 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
KHECPKLA_00696 1.69e-231 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KHECPKLA_00697 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
KHECPKLA_00698 6.45e-209 yitL - - S ko:K00243 - ko00000 S1 domain
KHECPKLA_00699 7.59e-215 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
KHECPKLA_00700 3.25e-81 ribT - - K ko:K02859 - ko00000 acetyltransferase
KHECPKLA_00701 2.78e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KHECPKLA_00702 1.2e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KHECPKLA_00703 1.92e-162 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KHECPKLA_00704 1.26e-82 - - - M - - - Lysin motif
KHECPKLA_00705 2.52e-124 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KHECPKLA_00706 9.85e-150 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
KHECPKLA_00707 5.27e-280 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
KHECPKLA_00708 5.59e-307 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
KHECPKLA_00709 7.91e-55 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KHECPKLA_00710 2.98e-295 XK27_05225 - - S - - - Tetratricopeptide repeat protein
KHECPKLA_00712 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
KHECPKLA_00713 2.76e-286 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
KHECPKLA_00714 1.46e-64 - - - V - - - Type I restriction modification DNA specificity domain
KHECPKLA_00715 5.3e-194 - - - L - - - Belongs to the 'phage' integrase family
KHECPKLA_00716 5.66e-111 - - - L - - - helicase activity
KHECPKLA_00717 6.39e-258 - - - K - - - DNA binding
KHECPKLA_00718 0.0 res 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
KHECPKLA_00719 2.48e-312 mod 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
KHECPKLA_00720 3.93e-78 yugI - - J ko:K07570 - ko00000 general stress protein
KHECPKLA_00721 1.57e-223 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
KHECPKLA_00722 4.16e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
KHECPKLA_00723 6.85e-131 - - - S - - - Protein of unknown function (DUF1461)
KHECPKLA_00724 1.15e-188 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KHECPKLA_00725 3.97e-125 yutD - - S - - - Protein of unknown function (DUF1027)
KHECPKLA_00726 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
KHECPKLA_00727 3.99e-74 - - - - - - - -
KHECPKLA_00728 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
KHECPKLA_00729 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
KHECPKLA_00730 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
KHECPKLA_00731 5.43e-31 - 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 2 family
KHECPKLA_00732 1.06e-156 - 3.2.1.31 - G ko:K01195 ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 2 family
KHECPKLA_00733 1.77e-236 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHECPKLA_00734 9.71e-309 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KHECPKLA_00735 7.82e-97 - - - S - - - Cupin domain
KHECPKLA_00736 1.27e-143 - - - S - - - Fic/DOC family
KHECPKLA_00737 6.27e-53 - - - S - - - Protein of unknown function (DUF3021)
KHECPKLA_00738 6.62e-59 - - - K - - - LytTr DNA-binding domain
KHECPKLA_00739 1.06e-117 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
KHECPKLA_00740 4e-145 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHECPKLA_00741 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHECPKLA_00742 0.0 - - - P ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
KHECPKLA_00743 1.05e-161 dhrS4 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
KHECPKLA_00744 2.33e-283 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
KHECPKLA_00745 1.09e-61 - - - - - - - -
KHECPKLA_00746 3.11e-85 - - - K - - - HxlR family
KHECPKLA_00747 1.87e-119 - 3.1.1.81 - S ko:K13075 ko02024,map02024 ko00000,ko00001,ko01000 Metallo-beta-lactamase superfamily
KHECPKLA_00748 1.75e-316 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
KHECPKLA_00749 6.61e-77 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
KHECPKLA_00750 1.07e-153 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHECPKLA_00751 4.91e-137 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
KHECPKLA_00752 3.45e-298 - - - - - - - -
KHECPKLA_00753 3.77e-42 ybbB - - S - - - Protein of unknown function (DUF1211)
KHECPKLA_00754 2.77e-94 - - - K - - - LytTr DNA-binding domain
KHECPKLA_00755 6.99e-66 - - - S - - - Protein of unknown function (DUF3021)
KHECPKLA_00756 1.54e-147 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
KHECPKLA_00757 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
KHECPKLA_00758 5.59e-39 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KHECPKLA_00759 4.52e-103 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
KHECPKLA_00760 6.97e-114 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_00761 5.34e-82 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_00762 7.92e-48 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_00763 6.37e-06 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KHECPKLA_00764 4.26e-16 - - - K - - - LysR substrate binding domain
KHECPKLA_00765 4.07e-226 - - - S - - - Conserved hypothetical protein 698
KHECPKLA_00766 2.16e-79 - - - - - - - -
KHECPKLA_00768 5.59e-128 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
KHECPKLA_00769 1.31e-122 - - - K - - - LysR substrate binding domain
KHECPKLA_00770 3.81e-225 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
KHECPKLA_00771 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KHECPKLA_00772 4.49e-114 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KHECPKLA_00773 4.07e-217 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
KHECPKLA_00774 4.45e-310 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KHECPKLA_00775 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KHECPKLA_00776 7.71e-193 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
KHECPKLA_00777 3.22e-165 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KHECPKLA_00778 3.87e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KHECPKLA_00779 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
KHECPKLA_00780 1.07e-47 yozE - - S - - - Belongs to the UPF0346 family
KHECPKLA_00781 1.95e-188 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
KHECPKLA_00782 5.61e-147 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
KHECPKLA_00783 6.92e-280 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KHECPKLA_00784 9.09e-204 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHECPKLA_00785 3.73e-232 - - - S ko:K07133 - ko00000 cog cog1373
KHECPKLA_00786 1.99e-211 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
KHECPKLA_00787 6.56e-114 - - - J ko:K10716 - ko00000,ko02000 Ion transport protein
KHECPKLA_00788 2.44e-21 - - - M - - - LysM domain
KHECPKLA_00789 1.06e-167 - - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
KHECPKLA_00791 2.84e-121 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
KHECPKLA_00797 8.82e-127 - - - M - - - lysozyme activity
KHECPKLA_00798 7.32e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KHECPKLA_00799 5.79e-269 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
KHECPKLA_00800 3.53e-295 cpdA - - S - - - Calcineurin-like phosphoesterase
KHECPKLA_00801 2.52e-217 degV1 - - S - - - DegV family
KHECPKLA_00802 4.05e-70 - - - - - - - -
KHECPKLA_00803 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
KHECPKLA_00804 1.69e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KHECPKLA_00805 1.79e-214 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
KHECPKLA_00806 4.43e-250 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KHECPKLA_00807 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KHECPKLA_00808 0.0 FbpA - - K - - - Fibronectin-binding protein
KHECPKLA_00809 5.5e-83 - - - - - - - -
KHECPKLA_00810 7.21e-205 - - - S - - - EDD domain protein, DegV family
KHECPKLA_00811 7.17e-188 - - - - - - - -
KHECPKLA_00812 7.82e-209 lysR - - K - - - Transcriptional regulator
KHECPKLA_00813 5.37e-249 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
KHECPKLA_00814 4.33e-131 - - - S - - - Protein of unknown function (DUF1275)
KHECPKLA_00815 2.27e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KHECPKLA_00816 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
KHECPKLA_00817 3.5e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
KHECPKLA_00818 2.81e-97 - - - K - - - Transcriptional regulator
KHECPKLA_00819 5.8e-110 - - - K - - - Transcriptional regulator
KHECPKLA_00820 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHECPKLA_00821 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KHECPKLA_00822 5.86e-148 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KHECPKLA_00823 3.71e-144 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
KHECPKLA_00824 8.3e-142 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
KHECPKLA_00825 1.25e-203 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
KHECPKLA_00826 1.09e-52 - - - C - - - Aldo/keto reductase family
KHECPKLA_00827 3.17e-150 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHECPKLA_00828 8.78e-237 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHECPKLA_00829 7.53e-187 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
KHECPKLA_00830 9.2e-38 - - - - - - - -
KHECPKLA_00831 5.31e-38 - - - - - - - -
KHECPKLA_00832 3.47e-146 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KHECPKLA_00833 1.47e-198 - - - S - - - Putative adhesin
KHECPKLA_00834 3.02e-142 - - - - - - - -
KHECPKLA_00835 2.13e-183 - - - S - - - Alpha/beta hydrolase family
KHECPKLA_00836 5.22e-199 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KHECPKLA_00837 4.49e-266 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KHECPKLA_00838 9.17e-126 - - - S - - - VanZ like family
KHECPKLA_00839 6.1e-171 yebC - - K - - - Transcriptional regulatory protein
KHECPKLA_00840 2.14e-208 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
KHECPKLA_00841 1.55e-215 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
KHECPKLA_00842 7.01e-50 comGC - - U ko:K02245,ko:K02456 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 Required for transformation and DNA binding
KHECPKLA_00843 1.15e-85 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
KHECPKLA_00844 8.46e-107 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
KHECPKLA_00845 5.24e-233 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
KHECPKLA_00846 1.41e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHECPKLA_00849 8.2e-109 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
KHECPKLA_00850 2.28e-149 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Levansucrase/Invertase
KHECPKLA_00851 4.77e-27 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
KHECPKLA_00852 3.87e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
KHECPKLA_00853 9.03e-85 - - - S - - - SdpI/YhfL protein family
KHECPKLA_00854 6.34e-165 - - - K - - - Transcriptional regulatory protein, C terminal
KHECPKLA_00855 0.0 yclK - - T - - - Histidine kinase
KHECPKLA_00856 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHECPKLA_00857 1.46e-134 vanZ - - V - - - VanZ like family
KHECPKLA_00858 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
KHECPKLA_00859 1.7e-275 - - - EGP - - - Major Facilitator
KHECPKLA_00860 5.96e-85 - - - - - - - -
KHECPKLA_00863 4e-247 ampC - - V - - - Beta-lactamase
KHECPKLA_00864 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
KHECPKLA_00865 2.75e-143 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
KHECPKLA_00866 2.56e-250 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KHECPKLA_00867 4.31e-194 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KHECPKLA_00868 7.46e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KHECPKLA_00869 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KHECPKLA_00870 7.09e-163 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
KHECPKLA_00871 9.31e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHECPKLA_00872 1.25e-75 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KHECPKLA_00873 1.09e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KHECPKLA_00874 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KHECPKLA_00875 2.86e-218 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KHECPKLA_00876 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KHECPKLA_00877 2.1e-94 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
KHECPKLA_00878 1.2e-39 - - - S - - - Protein of unknown function (DUF1146)
KHECPKLA_00879 1.18e-227 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
KHECPKLA_00880 2.09e-21 - - - S - - - DNA-directed RNA polymerase subunit beta
KHECPKLA_00881 2.74e-69 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
KHECPKLA_00882 3.08e-47 - - - S - - - Protein of unknown function (DUF2969)
KHECPKLA_00883 4.55e-285 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
KHECPKLA_00884 2.26e-105 uspA - - T - - - universal stress protein
KHECPKLA_00885 4.67e-08 - - - - - - - -
KHECPKLA_00886 8.75e-298 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
KHECPKLA_00887 1.83e-101 - - - S - - - Protein of unknown function (DUF1694)
KHECPKLA_00888 1.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KHECPKLA_00890 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KHECPKLA_00891 6.53e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KHECPKLA_00892 6.03e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KHECPKLA_00893 1.27e-138 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
KHECPKLA_00894 1.32e-234 - - - C - - - Glycerophosphoryl diester phosphodiesterase family
KHECPKLA_00895 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
KHECPKLA_00896 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KHECPKLA_00897 1.58e-282 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
KHECPKLA_00898 2.05e-156 - - - S - - - Haloacid dehalogenase-like hydrolase
KHECPKLA_00899 3.28e-140 radC - - L ko:K03630 - ko00000 DNA repair protein
KHECPKLA_00900 4.23e-223 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
KHECPKLA_00901 1.95e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
KHECPKLA_00902 1.1e-120 mreD - - - ko:K03571 - ko00000,ko03036 -
KHECPKLA_00903 1.66e-19 - - - S - - - Protein of unknown function (DUF4044)
KHECPKLA_00904 1.81e-67 - - - S - - - Protein of unknown function (DUF3397)
KHECPKLA_00905 1.55e-99 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
KHECPKLA_00906 3e-223 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KHECPKLA_00907 3.95e-73 ftsL - - D - - - Cell division protein FtsL
KHECPKLA_00908 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
KHECPKLA_00909 3.01e-225 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KHECPKLA_00910 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KHECPKLA_00911 7.52e-263 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KHECPKLA_00912 2.98e-190 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KHECPKLA_00913 5.8e-306 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KHECPKLA_00914 2.25e-301 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KHECPKLA_00915 1.49e-93 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KHECPKLA_00916 1.93e-47 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
KHECPKLA_00917 1.53e-175 ylmH - - S - - - S4 domain protein
KHECPKLA_00918 8.88e-158 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
KHECPKLA_00919 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KHECPKLA_00920 6.55e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
KHECPKLA_00921 1.27e-133 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
KHECPKLA_00922 2.6e-25 - - - - - - - -
KHECPKLA_00923 3.26e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KHECPKLA_00924 5.14e-268 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
KHECPKLA_00925 3e-75 XK27_04120 - - S - - - Putative amino acid metabolism
KHECPKLA_00926 1.36e-274 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KHECPKLA_00927 1.07e-159 pgm - - G - - - Phosphoglycerate mutase family
KHECPKLA_00928 2.59e-144 - - - S - - - repeat protein
KHECPKLA_00929 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KHECPKLA_00930 3.53e-204 ytlR - - I - - - Diacylglycerol kinase catalytic domain
KHECPKLA_00931 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHECPKLA_00932 8.85e-47 ykzG - - S - - - Belongs to the UPF0356 family
KHECPKLA_00933 2.79e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KHECPKLA_00934 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
KHECPKLA_00935 1.31e-266 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
KHECPKLA_00936 3.51e-65 ylbG - - S - - - UPF0298 protein
KHECPKLA_00937 5.38e-119 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
KHECPKLA_00938 1.78e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KHECPKLA_00939 1.85e-109 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KHECPKLA_00940 8.65e-79 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
KHECPKLA_00941 6.45e-110 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
KHECPKLA_00942 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
KHECPKLA_00943 1.72e-220 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
KHECPKLA_00944 1.97e-46 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
KHECPKLA_00945 1.68e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KHECPKLA_00946 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KHECPKLA_00947 6.17e-201 - - - - - - - -
KHECPKLA_00948 8.1e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KHECPKLA_00949 1.79e-278 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KHECPKLA_00950 3.4e-294 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KHECPKLA_00951 7.58e-134 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
KHECPKLA_00952 1.18e-108 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KHECPKLA_00953 2.91e-104 - - - - - - - -
KHECPKLA_00954 4.2e-102 - - - S - - - Domain of unknown function (DUF4767)
KHECPKLA_00955 3.92e-273 - - - - - - - -
KHECPKLA_00956 1.17e-144 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
KHECPKLA_00957 9.49e-205 - - - - - - - -
KHECPKLA_00958 2.28e-99 - - - K - - - DNA-templated transcription, initiation
KHECPKLA_00959 7.74e-215 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KHECPKLA_00960 2.15e-181 epsB - - M - - - biosynthesis protein
KHECPKLA_00961 7.42e-162 ywqD - - D - - - Capsular exopolysaccharide family
KHECPKLA_00962 6.12e-182 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
KHECPKLA_00963 1.88e-236 repA - - S - - - Replication initiator protein A
KHECPKLA_00964 1.85e-54 - - - L - - - Addiction module antitoxin, RelB DinJ family
KHECPKLA_00965 5.93e-37 - - - - - - - -
KHECPKLA_00966 8.07e-163 - - - S - - - protein conserved in bacteria
KHECPKLA_00967 2.09e-55 - - - - - - - -
KHECPKLA_00968 2.4e-37 - - - - - - - -
KHECPKLA_00969 0.0 traA - - L - - - MobA MobL family protein
KHECPKLA_00970 1.22e-68 - - - - - - - -
KHECPKLA_00971 3.42e-135 - - - - - - - -
KHECPKLA_00972 5.4e-69 - - - S - - - Cag pathogenicity island, type IV secretory system
KHECPKLA_00973 1.55e-70 - - - - - - - -
KHECPKLA_00974 5.23e-151 - - - - - - - -
KHECPKLA_00975 0.0 traE - - U - - - AAA-like domain
KHECPKLA_00976 6.16e-316 - - - S - - - WXG100 protein secretion system (Wss), protein YukC
KHECPKLA_00977 4.81e-263 - - - M - - - CHAP domain
KHECPKLA_00978 2.1e-125 - - - - - - - -
KHECPKLA_00979 3.28e-105 - - - - - - - -
KHECPKLA_00981 0.0 traK - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
KHECPKLA_00982 1.14e-83 - - - - - - - -
KHECPKLA_00983 8.39e-196 - - - - - - - -
KHECPKLA_00984 4.19e-87 - - - - - - - -
KHECPKLA_00985 0.0 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 This gene contains a nucleotide ambiguity which may be the result of a sequencing error
KHECPKLA_00986 5.3e-44 - - - - - - - -
KHECPKLA_00987 1.23e-254 - - - L - - - Psort location Cytoplasmic, score
KHECPKLA_00988 1.65e-102 - - - - - - - -
KHECPKLA_00989 4.39e-62 - - - L - - - Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHECPKLA_00990 5.66e-30 - - - L - - - Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHECPKLA_00992 9.93e-130 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KHECPKLA_00993 1.65e-102 - - - - - - - -
KHECPKLA_00994 2.82e-130 - - - - - - - -
KHECPKLA_00995 1.68e-52 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
KHECPKLA_00996 5.54e-39 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
KHECPKLA_00997 1.79e-172 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
KHECPKLA_00999 3.57e-156 - - - L - - - oxidized base lesion DNA N-glycosylase activity
KHECPKLA_01000 1.36e-96 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
KHECPKLA_01001 2.75e-64 - - - L ko:K07473 - ko00000,ko02048 bacterial-type proximal promoter sequence-specific DNA binding
KHECPKLA_01002 3.26e-68 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
KHECPKLA_01003 6.29e-296 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KHECPKLA_01004 1.99e-195 - - - K - - - Helix-turn-helix XRE-family like proteins
KHECPKLA_01005 1.45e-98 - - - - - - - -
KHECPKLA_01006 1.27e-19 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
KHECPKLA_01007 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
KHECPKLA_01008 1.45e-150 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KHECPKLA_01009 3.33e-110 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
KHECPKLA_01010 2.48e-101 - - - K - - - LytTr DNA-binding domain
KHECPKLA_01011 3.91e-167 - - - S - - - membrane
KHECPKLA_01012 3.69e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KHECPKLA_01013 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KHECPKLA_01014 4.1e-09 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHECPKLA_01015 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHECPKLA_01016 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
KHECPKLA_01017 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KHECPKLA_01018 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KHECPKLA_01019 2.44e-129 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KHECPKLA_01020 2.22e-234 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KHECPKLA_01021 9.39e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KHECPKLA_01022 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KHECPKLA_01023 3.04e-259 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KHECPKLA_01024 6.98e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
KHECPKLA_01025 6.08e-296 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KHECPKLA_01026 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KHECPKLA_01027 1.08e-56 yrzL - - S - - - Belongs to the UPF0297 family
KHECPKLA_01028 1.43e-95 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KHECPKLA_01029 5.16e-66 yrzB - - S - - - Belongs to the UPF0473 family
KHECPKLA_01030 3.65e-116 cvpA - - S - - - Colicin V production protein
KHECPKLA_01031 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KHECPKLA_01032 6.29e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
KHECPKLA_01033 2.57e-90 yslB - - S - - - Protein of unknown function (DUF2507)
KHECPKLA_01034 5.56e-178 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
KHECPKLA_01035 5.51e-147 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KHECPKLA_01036 4.15e-278 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KHECPKLA_01037 1.44e-201 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
KHECPKLA_01038 2.21e-34 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KHECPKLA_01039 1.47e-67 - - - - - - - -
KHECPKLA_01040 7.31e-269 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KHECPKLA_01041 2.02e-219 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
KHECPKLA_01042 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter transmembrane region
KHECPKLA_01043 1.72e-222 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
KHECPKLA_01044 1.69e-284 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KHECPKLA_01045 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
KHECPKLA_01046 6.69e-238 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
KHECPKLA_01047 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KHECPKLA_01048 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KHECPKLA_01049 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KHECPKLA_01050 4.11e-117 - - - S - - - Short repeat of unknown function (DUF308)
KHECPKLA_01051 3.19e-206 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
KHECPKLA_01052 2.68e-246 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
KHECPKLA_01053 1.12e-217 whiA - - K ko:K09762 - ko00000 May be required for sporulation
KHECPKLA_01054 3.74e-130 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KHECPKLA_01055 0.0 ycaM - - E - - - amino acid
KHECPKLA_01057 1.2e-129 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
KHECPKLA_01058 1.56e-80 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
KHECPKLA_01059 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KHECPKLA_01060 1.42e-286 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
KHECPKLA_01061 2.4e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KHECPKLA_01062 1.18e-311 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHECPKLA_01063 1.07e-39 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
KHECPKLA_01064 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KHECPKLA_01065 8.46e-101 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KHECPKLA_01066 4.26e-133 - - - K ko:K06977 - ko00000 acetyltransferase
KHECPKLA_01068 6.66e-195 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
KHECPKLA_01069 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
KHECPKLA_01070 7.94e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KHECPKLA_01071 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
KHECPKLA_01072 6.41e-265 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
KHECPKLA_01073 1.12e-188 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KHECPKLA_01074 1.19e-147 - - - C - - - nitroreductase
KHECPKLA_01075 3.09e-188 - - - C - - - Oxidoreductase
KHECPKLA_01076 3.52e-36 - - - - - - - -
KHECPKLA_01077 2.75e-90 - - - G - - - Ribose/Galactose Isomerase
KHECPKLA_01078 1.08e-143 - - - - - - - -
KHECPKLA_01079 1.55e-122 yokL3 - - J - - - Acetyltransferase (GNAT) domain
KHECPKLA_01080 1.02e-82 - - - K - - - sequence-specific DNA binding
KHECPKLA_01081 1.2e-172 - - - S - - - Protein of unknown function (DUF975)
KHECPKLA_01082 1.82e-180 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
KHECPKLA_01083 2.51e-173 - - - K - - - Helix-turn-helix domain
KHECPKLA_01084 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHECPKLA_01085 7.45e-14 yfhC - - C - - - nitroreductase
KHECPKLA_01086 5.78e-74 yfhC - - C - - - nitroreductase
KHECPKLA_01087 8.15e-39 - - - - - - - -
KHECPKLA_01088 1.92e-91 - - - K - - - Acetyltransferase (GNAT) domain
KHECPKLA_01089 7.09e-76 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHECPKLA_01090 8.02e-84 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KHECPKLA_01091 8.85e-177 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHECPKLA_01092 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KHECPKLA_01093 3.49e-221 ybbR - - S - - - YbbR-like protein
KHECPKLA_01094 1.29e-196 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KHECPKLA_01095 1.11e-262 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHECPKLA_01096 5.35e-176 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_01097 1.65e-177 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_01098 4.89e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHECPKLA_01099 9.47e-209 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
KHECPKLA_01100 1.51e-127 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KHECPKLA_01101 1.14e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
KHECPKLA_01102 9.67e-225 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
KHECPKLA_01103 4.61e-171 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KHECPKLA_01104 5.25e-198 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
KHECPKLA_01105 6.7e-119 - - - - - - - -
KHECPKLA_01106 6.97e-139 - - - S ko:K07045 - ko00000 Amidohydrolase
KHECPKLA_01107 2.82e-34 - - - S ko:K07045 - ko00000 Amidohydrolase
KHECPKLA_01108 1.31e-305 - - - L ko:K07478 - ko00000 AAA C-terminal domain
KHECPKLA_01109 4.33e-154 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KHECPKLA_01110 5.07e-104 - - - K - - - Acetyltransferase (GNAT) domain
KHECPKLA_01111 3.14e-62 - - - K - - - Acetyltransferase (GNAT) domain
KHECPKLA_01112 7.11e-223 XK27_00915 - - C - - - Luciferase-like monooxygenase
KHECPKLA_01113 2.38e-47 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
KHECPKLA_01114 3.75e-39 ywrO - - S - - - Flavodoxin-like fold
KHECPKLA_01115 7.67e-94 ogt 2.1.1.63 - L ko:K00567,ko:K10778 - ko00000,ko01000,ko03000,ko03400 6-O-methylguanine DNA methyltransferase, DNA binding domain
KHECPKLA_01116 1.34e-94 - - - K - - - Transcriptional regulator
KHECPKLA_01117 3.23e-18 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
KHECPKLA_01118 7.93e-31 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
KHECPKLA_01119 9.97e-111 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
KHECPKLA_01120 6.66e-115 - - - K - - - Acetyltransferase (GNAT) family
KHECPKLA_01121 1.02e-143 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
KHECPKLA_01122 1.88e-124 dpsB - - P - - - Belongs to the Dps family
KHECPKLA_01123 3.88e-46 - - - C - - - Heavy-metal-associated domain
KHECPKLA_01124 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
KHECPKLA_01125 3.27e-45 - - - S - - - Protein of unknown function (DUF3021)
KHECPKLA_01126 4.73e-121 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01127 8.36e-90 - - - S - - - pyridoxamine 5-phosphate
KHECPKLA_01128 6.53e-220 yobV3 - - K - - - WYL domain
KHECPKLA_01129 3.6e-38 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KHECPKLA_01130 1.02e-102 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KHECPKLA_01131 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
KHECPKLA_01132 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
KHECPKLA_01133 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
KHECPKLA_01134 2.72e-50 - - - K - - - helix_turn_helix, mercury resistance
KHECPKLA_01135 4.8e-58 - - - K - - - helix_turn_helix, mercury resistance
KHECPKLA_01136 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KHECPKLA_01137 1.64e-282 - - - G - - - Major Facilitator Superfamily
KHECPKLA_01138 1.7e-236 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KHECPKLA_01139 7.08e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
KHECPKLA_01140 9.78e-18 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KHECPKLA_01141 6.09e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
KHECPKLA_01142 2.21e-89 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KHECPKLA_01143 6.1e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KHECPKLA_01144 5.35e-140 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KHECPKLA_01145 8.36e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
KHECPKLA_01146 3.53e-170 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KHECPKLA_01147 3.9e-125 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KHECPKLA_01148 3.25e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KHECPKLA_01149 7.61e-190 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
KHECPKLA_01150 1.32e-43 - - - - - - - -
KHECPKLA_01151 2.7e-137 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
KHECPKLA_01152 6.96e-33 - - - - - - - -
KHECPKLA_01153 4.88e-104 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KHECPKLA_01154 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHECPKLA_01155 9.41e-69 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KHECPKLA_01156 2.53e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KHECPKLA_01157 3.68e-45 - - - S - - - Protein of unknown function (DUF2508)
KHECPKLA_01158 6.52e-143 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KHECPKLA_01159 1.66e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
KHECPKLA_01160 1.05e-192 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
KHECPKLA_01161 1.12e-76 yabA - - L - - - Involved in initiation control of chromosome replication
KHECPKLA_01162 5.67e-197 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KHECPKLA_01163 7.08e-166 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
KHECPKLA_01164 2.33e-112 - - - S - - - ECF transporter, substrate-specific component
KHECPKLA_01165 1.09e-163 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
KHECPKLA_01166 3.3e-125 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
KHECPKLA_01167 3.36e-248 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KHECPKLA_01168 3.16e-137 - - - - - - - -
KHECPKLA_01169 1.51e-313 eriC - - P ko:K03281 - ko00000 chloride
KHECPKLA_01170 4.12e-62 - - - - - - - -
KHECPKLA_01187 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KHECPKLA_01188 8.64e-230 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KHECPKLA_01189 1.48e-246 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
KHECPKLA_01190 3.22e-272 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
KHECPKLA_01202 1.32e-71 - - - - - - - -
KHECPKLA_01203 1e-206 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KHECPKLA_01204 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
KHECPKLA_01205 1.6e-32 - - - S - - - Sugar efflux transporter for intercellular exchange
KHECPKLA_01206 6.08e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KHECPKLA_01207 2.73e-127 - - - I - - - PAP2 superfamily
KHECPKLA_01209 1.75e-194 lysR5 - - K - - - LysR substrate binding domain
KHECPKLA_01210 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
KHECPKLA_01211 1.38e-310 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
KHECPKLA_01212 3.04e-110 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KHECPKLA_01213 2.52e-237 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KHECPKLA_01214 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KHECPKLA_01215 0.0 potE - - E - - - Amino Acid
KHECPKLA_01216 4.87e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KHECPKLA_01217 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KHECPKLA_01218 2.52e-28 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
KHECPKLA_01219 1.28e-156 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
KHECPKLA_01220 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KHECPKLA_01221 4.73e-250 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KHECPKLA_01222 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
KHECPKLA_01223 5.34e-108 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KHECPKLA_01224 7.61e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KHECPKLA_01225 1.15e-144 - - - S - - - GyrI-like small molecule binding domain
KHECPKLA_01226 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
KHECPKLA_01227 5.15e-218 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
KHECPKLA_01228 1.03e-205 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KHECPKLA_01229 6.74e-80 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KHECPKLA_01230 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KHECPKLA_01231 5.19e-61 - - - J - - - ribosomal protein
KHECPKLA_01232 4.39e-62 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
KHECPKLA_01233 1.63e-259 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
KHECPKLA_01234 1.62e-106 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
KHECPKLA_01235 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KHECPKLA_01236 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KHECPKLA_01237 4.77e-288 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
KHECPKLA_01238 1.37e-177 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
KHECPKLA_01239 4.3e-169 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KHECPKLA_01240 1.17e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KHECPKLA_01241 5.86e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
KHECPKLA_01242 9.76e-233 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KHECPKLA_01243 4.34e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
KHECPKLA_01244 4.77e-244 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
KHECPKLA_01245 3.48e-149 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
KHECPKLA_01246 7.55e-286 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
KHECPKLA_01247 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHECPKLA_01248 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHECPKLA_01249 4.85e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
KHECPKLA_01250 2.31e-44 ynzC - - S - - - UPF0291 protein
KHECPKLA_01251 3.88e-147 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KHECPKLA_01252 8.44e-143 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
KHECPKLA_01253 4.28e-92 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
KHECPKLA_01254 1.44e-148 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KHECPKLA_01255 3.71e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KHECPKLA_01256 1.37e-169 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
KHECPKLA_01257 2.51e-115 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KHECPKLA_01258 1.37e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
KHECPKLA_01259 1.34e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KHECPKLA_01260 1.17e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KHECPKLA_01261 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHECPKLA_01262 1.06e-210 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KHECPKLA_01263 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
KHECPKLA_01264 3.03e-158 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KHECPKLA_01265 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KHECPKLA_01266 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KHECPKLA_01267 1.84e-207 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHECPKLA_01268 1.29e-231 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_01269 4.13e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHECPKLA_01270 1.7e-241 oppD - - P ko:K02031 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
KHECPKLA_01271 6.2e-48 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
KHECPKLA_01272 6.25e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KHECPKLA_01273 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KHECPKLA_01274 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
KHECPKLA_01275 8.29e-75 yloU - - S - - - Asp23 family, cell envelope-related function
KHECPKLA_01276 9.04e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
KHECPKLA_01277 1.32e-41 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHECPKLA_01278 7.81e-201 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHECPKLA_01279 1.23e-296 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
KHECPKLA_01280 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
KHECPKLA_01281 2.18e-75 - - - - - - - -
KHECPKLA_01282 4.94e-131 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
KHECPKLA_01283 0.0 - - - S - - - TerB-C domain
KHECPKLA_01284 3.74e-316 - - - P - - - P-loop Domain of unknown function (DUF2791)
KHECPKLA_01285 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
KHECPKLA_01286 3.04e-45 - - - - - - - -
KHECPKLA_01287 2.57e-310 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KHECPKLA_01288 4.84e-316 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KHECPKLA_01289 5.74e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KHECPKLA_01290 7.99e-101 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
KHECPKLA_01291 3.48e-54 - - - M - - - Glycosyl transferase family 2
KHECPKLA_01292 7.54e-59 wbbK - - M - - - transferase activity, transferring glycosyl groups
KHECPKLA_01293 1.89e-30 rfbF - GT2 V ko:K12990 ko02024,ko02025,map02024,map02025 ko00000,ko00001,ko01000,ko01003,ko01005 Glycosyl transferase, family 2
KHECPKLA_01294 1.13e-75 - - - S - - - EpsG family
KHECPKLA_01295 6.53e-77 - - - M - - - Psort location Cytoplasmic, score
KHECPKLA_01296 9.69e-274 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
KHECPKLA_01297 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
KHECPKLA_01300 8.87e-12 - - - S - - - Macro domain
KHECPKLA_01302 6.73e-52 - - - S - - - Macro domain
KHECPKLA_01303 9.21e-18 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHECPKLA_01304 1.3e-46 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHECPKLA_01307 5.44e-129 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
KHECPKLA_01309 1.95e-176 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
KHECPKLA_01311 3.37e-232 flp - - V - - - Beta-lactamase
KHECPKLA_01312 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KHECPKLA_01313 2.97e-145 - - - S ko:K01992,ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
KHECPKLA_01314 7.11e-161 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01315 2.12e-309 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
KHECPKLA_01316 7.55e-207 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
KHECPKLA_01317 1.04e-122 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
KHECPKLA_01318 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01319 1.59e-182 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
KHECPKLA_01320 2.69e-152 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
KHECPKLA_01322 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
KHECPKLA_01323 5.04e-82 - - - S - - - Domain of unknown function (DUF4430)
KHECPKLA_01324 4.86e-113 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
KHECPKLA_01325 8.02e-119 - - - S - - - Cob(I)alamin adenosyltransferase
KHECPKLA_01326 9.11e-195 - - - M - - - transferase activity, transferring glycosyl groups
KHECPKLA_01327 5.49e-139 - - - S - - - glycosyl transferase family 2
KHECPKLA_01328 8.35e-279 - - - M - - - family 8
KHECPKLA_01329 1.88e-115 - - - M - - - family 8
KHECPKLA_01330 1.43e-108 - - - M - - - family 8
KHECPKLA_01331 0.0 - - - UW - - - Tetratricopeptide repeat
KHECPKLA_01333 3.85e-237 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KHECPKLA_01334 8.88e-265 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KHECPKLA_01335 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KHECPKLA_01336 6.16e-70 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec secretory system ASP3
KHECPKLA_01337 2.65e-236 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system GspB-transporter
KHECPKLA_01338 1.43e-163 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
KHECPKLA_01339 1.27e-88 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
KHECPKLA_01340 2.26e-84 secY2 - - U - - - Part of the accessory SecA2 SecY2 system specifically required for export of
KHECPKLA_01341 2.72e-90 - - - L - - - COG2826 Transposase and inactivated derivatives, IS30 family
KHECPKLA_01342 1e-145 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
KHECPKLA_01343 9.8e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
KHECPKLA_01344 1.2e-204 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KHECPKLA_01345 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
KHECPKLA_01346 1.06e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
KHECPKLA_01347 2.47e-291 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KHECPKLA_01348 3.63e-219 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KHECPKLA_01349 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KHECPKLA_01350 1.63e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KHECPKLA_01351 5.97e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
KHECPKLA_01352 2.02e-62 - - - - - - - -
KHECPKLA_01353 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
KHECPKLA_01354 4.88e-195 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
KHECPKLA_01355 4.5e-200 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
KHECPKLA_01356 1.93e-46 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHECPKLA_01357 7.29e-316 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KHECPKLA_01358 8.69e-195 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KHECPKLA_01359 1.6e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KHECPKLA_01360 1.47e-95 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
KHECPKLA_01361 6.05e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHECPKLA_01362 9.75e-253 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
KHECPKLA_01363 9.89e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
KHECPKLA_01364 1.67e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
KHECPKLA_01365 3.27e-80 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
KHECPKLA_01366 3.01e-189 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHECPKLA_01367 3.44e-286 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
KHECPKLA_01368 1.17e-17 - - - - - - - -
KHECPKLA_01369 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
KHECPKLA_01370 6.76e-119 - - - S - - - ECF-type riboflavin transporter, S component
KHECPKLA_01371 1.72e-152 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
KHECPKLA_01372 2.36e-68 - - - - - - - -
KHECPKLA_01373 4.55e-71 - - - K - - - Acetyltransferase (GNAT) domain
KHECPKLA_01374 0.0 - - - S - - - Predicted membrane protein (DUF2207)
KHECPKLA_01375 1.36e-256 - - - P - - - Major Facilitator Superfamily
KHECPKLA_01376 1.18e-222 - - - I - - - Carboxylesterase family
KHECPKLA_01377 6.67e-204 - - - K - - - helix_turn_helix, arabinose operon control protein
KHECPKLA_01378 1.58e-209 - - - GK - - - ROK family
KHECPKLA_01379 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHECPKLA_01380 4.01e-80 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
KHECPKLA_01381 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KHECPKLA_01382 2.98e-89 - - - K - - - MerR HTH family regulatory protein
KHECPKLA_01383 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
KHECPKLA_01384 3.54e-101 - - - S - - - Domain of unknown function (DUF4811)
KHECPKLA_01385 2.15e-160 pnb - - C - - - nitroreductase
KHECPKLA_01386 3.01e-14 - - - - - - - -
KHECPKLA_01387 4.43e-205 - - - S - - - peptidoglycan catabolic process
KHECPKLA_01393 2.55e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KHECPKLA_01394 1.3e-261 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
KHECPKLA_01395 3.86e-305 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KHECPKLA_01396 1.05e-165 - - - S - - - PAS domain
KHECPKLA_01397 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
KHECPKLA_01398 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KHECPKLA_01399 3.47e-160 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
KHECPKLA_01400 2.08e-84 - - - - - - - -
KHECPKLA_01401 1.31e-103 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KHECPKLA_01402 1.2e-169 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_01403 6.4e-70 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHECPKLA_01404 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHECPKLA_01405 1.4e-187 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
KHECPKLA_01406 7.93e-110 - - - S - - - PAS domain
KHECPKLA_01407 2.06e-297 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KHECPKLA_01408 3.73e-94 - - - S - - - Protein of unknown function (DUF3290)
KHECPKLA_01409 4.85e-143 yviA - - S - - - Protein of unknown function (DUF421)
KHECPKLA_01410 3.79e-180 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KHECPKLA_01411 1.83e-231 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
KHECPKLA_01412 1.95e-251 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
KHECPKLA_01413 1.01e-189 dkgB - - S - - - reductase
KHECPKLA_01414 7.45e-196 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
KHECPKLA_01415 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHECPKLA_01416 5.68e-258 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHECPKLA_01417 2.51e-201 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
KHECPKLA_01418 2.79e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHECPKLA_01419 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
KHECPKLA_01420 7.66e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
KHECPKLA_01421 6.5e-73 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
KHECPKLA_01422 2.49e-89 yybA - - K - - - Transcriptional regulator
KHECPKLA_01423 7.39e-108 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KHECPKLA_01424 4.41e-96 yjcF - - S - - - Acetyltransferase (GNAT) domain
KHECPKLA_01425 1.59e-214 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
KHECPKLA_01426 1.14e-206 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KHECPKLA_01427 1.16e-123 yobS - - K - - - Bacterial regulatory proteins, tetR family
KHECPKLA_01428 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
KHECPKLA_01429 2.04e-158 - - - S - - - haloacid dehalogenase-like hydrolase
KHECPKLA_01430 1.27e-156 - - - S - - - SNARE associated Golgi protein
KHECPKLA_01431 1.31e-223 - - - - - - - -
KHECPKLA_01432 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
KHECPKLA_01433 2.62e-138 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
KHECPKLA_01434 5.45e-28 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
KHECPKLA_01435 2.05e-183 - - - I - - - alpha/beta hydrolase fold
KHECPKLA_01436 4.21e-138 - - - S - - - SNARE associated Golgi protein
KHECPKLA_01437 3.4e-125 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
KHECPKLA_01438 6.19e-300 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KHECPKLA_01439 1.38e-155 - - - - - - - -
KHECPKLA_01442 0.000183 - - - S - - - Domain of unknown function (DUF4176)
KHECPKLA_01443 7.65e-83 traA - - L - - - MobA/MobL family
KHECPKLA_01444 6.74e-80 - - - S - - - Phage derived protein Gp49-like (DUF891)
KHECPKLA_01445 1.1e-56 - - - K - - - Helix-turn-helix domain
KHECPKLA_01446 1.08e-37 - - - S - - - Bacterial epsilon antitoxin
KHECPKLA_01448 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHECPKLA_01449 1.38e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01450 4.16e-117 - - - F - - - AAA domain
KHECPKLA_01452 1.5e-24 slyA - - K - - - DNA-binding transcription factor activity
KHECPKLA_01453 4.21e-129 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
KHECPKLA_01454 5.17e-250 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHECPKLA_01455 3.99e-96 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
KHECPKLA_01456 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHECPKLA_01457 9.73e-273 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
KHECPKLA_01458 1.23e-34 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
KHECPKLA_01459 4.39e-18 - - - - - - - -
KHECPKLA_01461 2.04e-117 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
KHECPKLA_01462 8.1e-44 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
KHECPKLA_01463 1.1e-46 - - - - - - - -
KHECPKLA_01467 1.12e-241 - 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 Involved in molybdopterin and thiamine biosynthesis, family 2
KHECPKLA_01470 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHECPKLA_01471 2.76e-288 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KHECPKLA_01472 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KHECPKLA_01473 6.59e-225 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
KHECPKLA_01474 5.68e-181 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
KHECPKLA_01475 1.42e-170 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01476 0.0 - - - E - - - amino acid
KHECPKLA_01477 1.28e-54 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
KHECPKLA_01478 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KHECPKLA_01479 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KHECPKLA_01480 4.13e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KHECPKLA_01481 2.11e-272 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KHECPKLA_01482 5.46e-161 - - - S - - - (CBS) domain
KHECPKLA_01483 2.31e-231 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KHECPKLA_01484 2.58e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KHECPKLA_01485 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KHECPKLA_01486 1.75e-46 yabO - - J - - - S4 domain protein
KHECPKLA_01487 5.29e-78 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
KHECPKLA_01488 6.12e-76 - - - J ko:K07571 - ko00000 S1 RNA binding domain
KHECPKLA_01489 7.92e-289 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KHECPKLA_01490 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KHECPKLA_01491 0.0 - - - S - - - membrane
KHECPKLA_01492 2.53e-202 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KHECPKLA_01493 2.64e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KHECPKLA_01494 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
KHECPKLA_01497 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KHECPKLA_01498 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHECPKLA_01499 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHECPKLA_01500 1.65e-141 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
KHECPKLA_01501 3.6e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KHECPKLA_01502 1.14e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KHECPKLA_01503 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KHECPKLA_01504 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
KHECPKLA_01505 8.75e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KHECPKLA_01506 3.16e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
KHECPKLA_01507 7.29e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KHECPKLA_01508 4.01e-198 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KHECPKLA_01509 6.08e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KHECPKLA_01510 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KHECPKLA_01511 3.04e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KHECPKLA_01512 4.26e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KHECPKLA_01513 2.92e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
KHECPKLA_01514 7.74e-56 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KHECPKLA_01515 8.55e-78 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KHECPKLA_01516 1.67e-46 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KHECPKLA_01517 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KHECPKLA_01518 1.73e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KHECPKLA_01519 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KHECPKLA_01520 1.76e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KHECPKLA_01521 1.09e-74 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KHECPKLA_01522 9.33e-107 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KHECPKLA_01523 3.44e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
KHECPKLA_01524 5.78e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
KHECPKLA_01525 1.15e-297 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KHECPKLA_01526 4.87e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KHECPKLA_01527 4.46e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KHECPKLA_01528 1.89e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
KHECPKLA_01529 4.53e-72 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KHECPKLA_01530 4.46e-81 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KHECPKLA_01531 4.41e-219 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KHECPKLA_01532 1.91e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
KHECPKLA_01533 5.52e-185 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHECPKLA_01534 7.99e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHECPKLA_01535 1.04e-178 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KHECPKLA_01536 1.1e-190 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KHECPKLA_01537 7.82e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KHECPKLA_01538 7.96e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
KHECPKLA_01539 2.59e-90 - - - - - - - -
KHECPKLA_01540 5.03e-197 - - - GM - - - NmrA-like family
KHECPKLA_01541 2.1e-140 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
KHECPKLA_01542 1.45e-162 - - - G - - - Belongs to the phosphoglycerate mutase family
KHECPKLA_01543 1.31e-68 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
KHECPKLA_01544 1.61e-196 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
KHECPKLA_01545 1.54e-55 - - - - - - - -
KHECPKLA_01546 1.1e-34 - - - - - - - -
KHECPKLA_01547 1.43e-161 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KHECPKLA_01548 8.09e-235 - - - S - - - AAA domain
KHECPKLA_01549 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
KHECPKLA_01550 7.41e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
KHECPKLA_01551 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KHECPKLA_01552 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KHECPKLA_01553 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
KHECPKLA_01554 8.55e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KHECPKLA_01555 5.44e-178 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KHECPKLA_01556 7.35e-191 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
KHECPKLA_01557 9e-74 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
KHECPKLA_01558 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
KHECPKLA_01559 0.0 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHECPKLA_01560 6.82e-128 - - - K ko:K03091 - ko00000,ko03021 sigma factor activity
KHECPKLA_01561 1.19e-45 - - - - - - - -
KHECPKLA_01562 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
KHECPKLA_01564 1.92e-244 - - - S - - - Phage minor structural protein
KHECPKLA_01565 2.74e-160 - - - S - - - Phage tail protein
KHECPKLA_01566 0.0 - - - L - - - Phage tail tape measure protein TP901
KHECPKLA_01572 1.15e-49 - - - S - - - Phage gp6-like head-tail connector protein
KHECPKLA_01573 2.95e-249 - - - S - - - peptidase activity
KHECPKLA_01574 4.39e-144 - - - S - - - Clp protease
KHECPKLA_01575 2.22e-203 - - - S - - - Phage portal protein
KHECPKLA_01577 0.0 - - - S - - - Phage Terminase
KHECPKLA_01578 4.21e-100 - - - S - - - Phage terminase, small subunit
KHECPKLA_01579 5.92e-108 - - - S - - - HNH endonuclease
KHECPKLA_01580 2.16e-98 - - - S - - - Phage transcriptional regulator, ArpU family
KHECPKLA_01582 9.18e-56 - - - S - - - VRR_NUC
KHECPKLA_01591 1.82e-32 - - - - - - - -
KHECPKLA_01596 5.4e-82 - - - L - - - Psort location Cytoplasmic, score
KHECPKLA_01599 5.94e-42 - - - - - - - -
KHECPKLA_01606 3.57e-21 - - - K - - - Cro/C1-type HTH DNA-binding domain
KHECPKLA_01609 3.56e-41 - - - - - - - -
KHECPKLA_01610 1.5e-139 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
KHECPKLA_01613 3.79e-07 - - - - - - - -
KHECPKLA_01614 1.32e-118 - - - K - - - ORF6N domain
KHECPKLA_01616 1.51e-90 - - - K - - - Peptidase S24-like
KHECPKLA_01617 1.45e-34 - - - S - - - Domain of unknown function (DUF4145)
KHECPKLA_01620 2.19e-155 - - - V - - - Abi-like protein
KHECPKLA_01621 2.3e-276 - - - S - - - Phage integrase family
KHECPKLA_01622 1.94e-268 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
KHECPKLA_01623 1.01e-128 - - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
KHECPKLA_01624 1.47e-87 - - - - - - - -
KHECPKLA_01625 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KHECPKLA_01627 1.32e-157 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHECPKLA_01628 5.79e-171 - - - S - - - haloacid dehalogenase-like hydrolase
KHECPKLA_01629 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
KHECPKLA_01630 1.69e-106 - - - - - - - -
KHECPKLA_01631 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KHECPKLA_01632 5.25e-282 sptS - - T - - - Histidine kinase
KHECPKLA_01633 2.38e-148 dltr - - K - - - response regulator
KHECPKLA_01634 3.89e-145 - - - T - - - Region found in RelA / SpoT proteins
KHECPKLA_01635 3.31e-148 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
KHECPKLA_01636 1.2e-86 - - - O - - - OsmC-like protein
KHECPKLA_01637 0.0 - - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KHECPKLA_01638 1.73e-222 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01639 2.76e-184 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_01640 1.94e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
KHECPKLA_01641 6.52e-198 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
KHECPKLA_01642 1.21e-206 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
KHECPKLA_01643 3.21e-99 ykuP - - C ko:K03839 - ko00000 Flavodoxin
KHECPKLA_01644 1.6e-108 gtcA1 - - S - - - Teichoic acid glycosylation protein
KHECPKLA_01645 1.44e-271 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KHECPKLA_01647 1.34e-313 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHECPKLA_01648 3.48e-258 yfmL - - L - - - DEAD DEAH box helicase
KHECPKLA_01649 4.84e-174 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
KHECPKLA_01650 4.22e-295 - - - E ko:K03294 - ko00000 amino acid
KHECPKLA_01651 9.63e-130 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KHECPKLA_01652 1.81e-316 yhdP - - S - - - Transporter associated domain
KHECPKLA_01653 5.01e-165 - - - - - - - -
KHECPKLA_01654 1.89e-148 - - - C - - - nitroreductase
KHECPKLA_01655 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
KHECPKLA_01656 1.64e-170 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
KHECPKLA_01657 4.33e-69 - - - S - - - Enterocin A Immunity
KHECPKLA_01658 2.4e-172 gntR - - K - - - UbiC transcription regulator-associated domain protein
KHECPKLA_01659 6.33e-212 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
KHECPKLA_01660 5.01e-160 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KHECPKLA_01661 2.41e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KHECPKLA_01663 6.64e-109 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
KHECPKLA_01664 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
KHECPKLA_01665 1.67e-151 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
KHECPKLA_01666 8.68e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHECPKLA_01667 3.84e-190 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KHECPKLA_01668 2.05e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
KHECPKLA_01669 1.4e-215 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
KHECPKLA_01670 9.27e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
KHECPKLA_01671 3.53e-118 - - - K - - - Acetyltransferase (GNAT) domain
KHECPKLA_01672 1.17e-164 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01673 7.71e-154 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KHECPKLA_01674 8.02e-160 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
KHECPKLA_01675 1.1e-197 - - - S - - - Phospholipase, patatin family
KHECPKLA_01676 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
KHECPKLA_01677 6.29e-68 - - - S - - - Enterocin A Immunity
KHECPKLA_01680 1.66e-42 - - - S - - - Enterocin A Immunity
KHECPKLA_01681 1.36e-05 blpT - - - - - - -
KHECPKLA_01684 5.26e-15 - - - S - - - Bacteriocin class II with double-glycine leader peptide
KHECPKLA_01685 1.34e-108 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
KHECPKLA_01686 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KHECPKLA_01687 2.08e-157 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
KHECPKLA_01688 8.31e-240 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
KHECPKLA_01690 1.65e-258 - - - EGP - - - Major facilitator superfamily
KHECPKLA_01691 5.37e-145 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
KHECPKLA_01692 1.98e-115 - - - S - - - Putative adhesin
KHECPKLA_01693 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHECPKLA_01694 6.19e-161 treR - - K ko:K03486 - ko00000,ko03000 UTRA
KHECPKLA_01695 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
KHECPKLA_01696 3.56e-191 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_01697 7.62e-138 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_01698 1.5e-142 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_01699 1.54e-187 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHECPKLA_01700 4.37e-176 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01701 2.88e-184 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHECPKLA_01702 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
KHECPKLA_01703 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01704 1.07e-87 - - - K - - - Transcriptional regulator, MarR family
KHECPKLA_01705 1.84e-186 - - - S - - - Alpha beta hydrolase
KHECPKLA_01706 1.63e-264 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
KHECPKLA_01707 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
KHECPKLA_01708 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
KHECPKLA_01709 3.01e-312 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
KHECPKLA_01710 0.0 - - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
KHECPKLA_01711 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
KHECPKLA_01712 1.07e-262 pepA - - E - - - M42 glutamyl aminopeptidase
KHECPKLA_01713 3.52e-103 - - - - - - - -
KHECPKLA_01714 1.13e-92 rmaE - - K - - - helix_turn_helix multiple antibiotic resistance protein
KHECPKLA_01715 1.81e-41 - - - - - - - -
KHECPKLA_01716 5.79e-270 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
KHECPKLA_01717 0.0 - - - E - - - Amino acid permease
KHECPKLA_01718 6.37e-90 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_01719 6.29e-139 - - - E ko:K02054 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHECPKLA_01720 4.34e-153 potC3 - - E ko:K02053 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
KHECPKLA_01721 4.2e-191 potA11 3.6.3.30 - P ko:K02010,ko:K02052 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KHECPKLA_01722 2.57e-189 - - - P ko:K02055 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
KHECPKLA_01723 1.06e-313 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Adenine deaminase C-terminal domain
KHECPKLA_01724 1.81e-263 - - - E - - - Phospholipase B
KHECPKLA_01725 8.28e-143 - - - I - - - Acid phosphatase homologues
KHECPKLA_01726 2e-185 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
KHECPKLA_01727 1.31e-251 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha-amylase domain
KHECPKLA_01728 3.61e-96 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHECPKLA_01729 3.43e-186 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHECPKLA_01730 9.3e-125 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
KHECPKLA_01731 1.21e-213 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
KHECPKLA_01732 0.0 - - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
KHECPKLA_01733 0.0 - - - C - - - FMN_bind
KHECPKLA_01734 1.78e-209 - - - K - - - LysR family
KHECPKLA_01735 0.0 lacG 3.2.1.21, 3.2.1.85 - G ko:K01220,ko:K05350 ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHECPKLA_01736 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
KHECPKLA_01737 1.02e-74 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
KHECPKLA_01738 1.17e-186 lacT - - K ko:K02531 - ko00000,ko03000 CAT RNA binding domain
KHECPKLA_01739 3.59e-52 - - - - - - - -
KHECPKLA_01740 5.75e-309 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
KHECPKLA_01741 1.81e-67 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
KHECPKLA_01742 2e-110 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KHECPKLA_01743 5.07e-166 - - - S - - - Domain of unknown function (DUF4867)
KHECPKLA_01744 9.58e-136 - 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
KHECPKLA_01745 9.37e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
KHECPKLA_01746 2.11e-172 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
KHECPKLA_01747 1e-304 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
KHECPKLA_01748 2.58e-171 - - - K - - - Transcriptional regulator
KHECPKLA_01749 9.32e-183 - - - S - - - hydrolase
KHECPKLA_01750 1.25e-168 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KHECPKLA_01751 2.05e-98 - - - K - - - acetyltransferase
KHECPKLA_01752 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
KHECPKLA_01753 3.74e-45 - - - K - - - Bacterial regulatory proteins, tetR family
KHECPKLA_01754 2.63e-15 - - - - - - - -
KHECPKLA_01755 5.84e-46 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHECPKLA_01756 5.87e-244 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHECPKLA_01757 0.0 qacA - - EGP - - - Major Facilitator
KHECPKLA_01758 0.0 qacA - - EGP - - - Major Facilitator
KHECPKLA_01759 3.67e-185 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
KHECPKLA_01760 2.26e-170 - - - S ko:K07052 - ko00000 CAAX amino terminal protease
KHECPKLA_01761 2e-197 - - - S ko:K07088 - ko00000 Membrane transport protein
KHECPKLA_01762 1.05e-123 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
KHECPKLA_01763 1.75e-230 - - - S - - - Bacteriocin helveticin-J
KHECPKLA_01764 2.32e-51 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
KHECPKLA_01765 1.08e-71 ylbE - - GM - - - NAD(P)H-binding
KHECPKLA_01766 6.1e-29 ylbE - - GM - - - NAD(P)H-binding
KHECPKLA_01767 1.2e-162 - - - F - - - Glutamine amidotransferase class-I
KHECPKLA_01768 2.5e-122 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
KHECPKLA_01770 4.63e-74 - - - S - - - Antibiotic biosynthesis monooxygenase
KHECPKLA_01771 2.24e-87 - - - K ko:K03827 - ko00000,ko01000 Acetyltransferase (GNAT) domain
KHECPKLA_01772 6.01e-61 - - - - - - - -
KHECPKLA_01773 3.12e-220 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
KHECPKLA_01774 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
KHECPKLA_01775 2.22e-201 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KHECPKLA_01776 8.25e-154 - - - M - - - ErfK YbiS YcfS YnhG
KHECPKLA_01777 3.55e-181 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KHECPKLA_01778 8.47e-160 - - - - - - - -
KHECPKLA_01779 9.78e-258 - - - I - - - Protein of unknown function (DUF2974)
KHECPKLA_01780 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
KHECPKLA_01781 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
KHECPKLA_01782 2.56e-145 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
KHECPKLA_01783 0.0 mdr - - EGP - - - Major Facilitator
KHECPKLA_01784 8.89e-276 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KHECPKLA_01788 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
KHECPKLA_01789 1.33e-77 - - - I - - - alpha/beta hydrolase fold
KHECPKLA_01790 1.32e-19 - - - - - - - -
KHECPKLA_01791 2.51e-109 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
KHECPKLA_01792 5.78e-39 - - - - - - - -
KHECPKLA_01793 1.89e-183 - - - D - - - AAA domain
KHECPKLA_01794 1.32e-214 repA - - S - - - Replication initiator protein A
KHECPKLA_01795 8.11e-58 - - - L ko:K07473 - ko00000,ko02048 Addiction module antitoxin, RelB DinJ family
KHECPKLA_01796 7.29e-111 - - - - - - - -
KHECPKLA_01797 2.85e-53 - - - - - - - -
KHECPKLA_01798 4.03e-37 - - - - - - - -
KHECPKLA_01799 0.0 traA - - L - - - MobA MobL family protein
KHECPKLA_01801 3.5e-56 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KHECPKLA_01802 3.3e-200 - - - S ko:K07133 - ko00000 cog cog1373
KHECPKLA_01803 2.7e-104 tnpR1 - - L - - - Resolvase, N terminal domain
KHECPKLA_01804 6.19e-315 merA 1.16.1.1 - C ko:K00520,ko:K21739 - ko00000,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KHECPKLA_01805 3.7e-186 B4168_4126 - - L ko:K07493 - ko00000 Transposase
KHECPKLA_01806 7.08e-108 pnuC - - H ko:K03811 - ko00000,ko02000 Nicotinamide mononucleotide transporter
KHECPKLA_01807 5.91e-234 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
KHECPKLA_01808 1.75e-166 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
KHECPKLA_01809 2.46e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
KHECPKLA_01810 6.05e-86 - - - S - - - Domain of unknown function (DUF956)
KHECPKLA_01811 8.98e-317 yifK - - E ko:K03293 - ko00000 Amino acid permease
KHECPKLA_01812 2.16e-290 yifK - - E ko:K03293 - ko00000 Amino acid permease
KHECPKLA_01813 1.56e-172 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
KHECPKLA_01814 4.7e-301 - - - E - - - amino acid
KHECPKLA_01815 9.68e-259 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
KHECPKLA_01816 1.14e-244 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
KHECPKLA_01817 3.58e-206 - - - EG - - - EamA-like transporter family
KHECPKLA_01818 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
KHECPKLA_01819 5.7e-168 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
KHECPKLA_01820 2.1e-187 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
KHECPKLA_01821 2.13e-183 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KHECPKLA_01822 1.63e-234 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
KHECPKLA_01823 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
KHECPKLA_01824 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHECPKLA_01825 3.2e-41 - - - - - - - -
KHECPKLA_01830 1.53e-44 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
KHECPKLA_01832 2.96e-116 ymdB - - S - - - Macro domain protein
KHECPKLA_01833 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
KHECPKLA_01834 2.21e-156 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
KHECPKLA_01835 5.12e-285 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
KHECPKLA_01836 4.82e-199 - - - - - - - -
KHECPKLA_01837 4.5e-68 aroD 1.1.1.25, 4.2.1.10 - E ko:K03785,ko:K13832 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 3-dehydroquinate dehydratase activity
KHECPKLA_01838 1.04e-210 - - - C - - - Domain of unknown function (DUF4931)
KHECPKLA_01839 2.81e-196 - - - K - - - Helix-turn-helix domain, rpiR family
KHECPKLA_01840 1.82e-177 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
KHECPKLA_01841 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
KHECPKLA_01842 7.74e-202 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KHECPKLA_01843 1.14e-159 - - - - - - - -
KHECPKLA_01844 4.81e-69 - - - - - - - -
KHECPKLA_01845 7.82e-168 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
KHECPKLA_01846 5.7e-132 - - - S - - - Protein of unknown function (DUF975)
KHECPKLA_01847 1.57e-174 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
KHECPKLA_01848 3.86e-143 - - - G - - - Phosphoglycerate mutase family
KHECPKLA_01849 1.47e-138 - - - G - - - phosphoglycerate mutase
KHECPKLA_01850 2.15e-116 - - - K - - - Bacterial regulatory proteins, tetR family
KHECPKLA_01851 1.8e-228 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
KHECPKLA_01852 2.18e-146 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01853 2.07e-202 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KHECPKLA_01854 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHECPKLA_01855 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHECPKLA_01856 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
KHECPKLA_01857 6.73e-51 - - - - - - - -
KHECPKLA_01858 1.4e-140 - - - K - - - WHG domain
KHECPKLA_01859 1.1e-126 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KHECPKLA_01860 6.07e-126 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
KHECPKLA_01861 1.43e-248 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
KHECPKLA_01862 6.89e-189 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
KHECPKLA_01863 9e-226 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KHECPKLA_01864 1.24e-122 cvpA - - S - - - Colicin V production protein
KHECPKLA_01865 1.27e-161 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
KHECPKLA_01866 2.76e-192 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KHECPKLA_01867 3.52e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
KHECPKLA_01868 7.4e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
KHECPKLA_01869 3.02e-57 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
KHECPKLA_01870 2.68e-254 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KHECPKLA_01871 2.76e-184 - - - S - - - Protein of unknown function (DUF1129)
KHECPKLA_01872 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01873 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
KHECPKLA_01874 2.39e-156 vanR - - K - - - response regulator
KHECPKLA_01875 5.3e-264 - - - T - - - His Kinase A (phosphoacceptor) domain
KHECPKLA_01876 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KHECPKLA_01877 3.05e-183 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
KHECPKLA_01878 2.23e-205 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01879 3.62e-258 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
KHECPKLA_01880 2.53e-28 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
KHECPKLA_01881 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
KHECPKLA_01882 1.27e-172 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
KHECPKLA_01883 2.97e-213 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KHECPKLA_01884 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
KHECPKLA_01885 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KHECPKLA_01886 5.31e-175 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
KHECPKLA_01887 4.8e-57 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
KHECPKLA_01888 2.83e-197 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
KHECPKLA_01889 5.02e-149 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
KHECPKLA_01890 1.11e-167 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
KHECPKLA_01891 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
KHECPKLA_01892 2.55e-88 - - - S - - - PD-(D/E)XK nuclease family transposase
KHECPKLA_01893 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
KHECPKLA_01894 3.49e-270 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
KHECPKLA_01895 6.35e-51 - - - - - - - -
KHECPKLA_01896 6.28e-78 - - - - - - - -
KHECPKLA_01897 0.0 - - - S - - - ABC transporter, ATP-binding protein
KHECPKLA_01898 8.94e-177 - - - S - - - Putative threonine/serine exporter
KHECPKLA_01899 1.1e-103 - - - S - - - Threonine/Serine exporter, ThrE
KHECPKLA_01900 1.75e-52 - - - - - - - -
KHECPKLA_01901 8.86e-78 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
KHECPKLA_01902 6.23e-102 - - - - - - - -
KHECPKLA_01903 4.05e-222 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KHECPKLA_01904 4.34e-104 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
KHECPKLA_01905 7.47e-141 - - - - - - - -
KHECPKLA_01906 0.0 - - - S - - - O-antigen ligase like membrane protein
KHECPKLA_01907 3.52e-58 - - - - - - - -
KHECPKLA_01908 2.78e-125 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
KHECPKLA_01910 2.04e-172 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
KHECPKLA_01911 2.81e-287 - - - S - - - Putative peptidoglycan binding domain
KHECPKLA_01912 1.68e-295 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KHECPKLA_01914 1.55e-175 natA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
KHECPKLA_01915 3.6e-159 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
KHECPKLA_01916 5.54e-156 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
KHECPKLA_01917 0.0 - - - E - - - Amino Acid
KHECPKLA_01918 7.37e-170 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01919 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
KHECPKLA_01920 2.72e-156 gpm2 - - G - - - Phosphoglycerate mutase family
KHECPKLA_01921 1.66e-32 - - - - - - - -
KHECPKLA_01922 2.44e-66 - - - - - - - -
KHECPKLA_01923 5.51e-185 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
KHECPKLA_01924 0.0 ptsG 2.7.1.199, 2.7.1.208 - G ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
KHECPKLA_01925 6.62e-164 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KHECPKLA_01926 9.56e-178 - - - K - - - Helix-turn-helix domain, rpiR family
KHECPKLA_01927 1.68e-60 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
KHECPKLA_01928 4.85e-315 - - - M - - - ErfK YbiS YcfS YnhG
KHECPKLA_01929 0.0 - 3.6.3.8 - P ko:K01537 - ko00000,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
KHECPKLA_01931 3.57e-151 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
KHECPKLA_01932 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
KHECPKLA_01934 6.33e-167 - - - S - - - Peptidase_C39 like family
KHECPKLA_01935 1.97e-159 - - - K - - - Helix-turn-helix domain, rpiR family
KHECPKLA_01936 2.16e-105 - - - L - - - MgsA AAA+ ATPase C terminal
KHECPKLA_01937 1.23e-308 lacE 2.7.1.207 - G ko:K02761,ko:K02787,ko:K02788 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KHECPKLA_01938 3.23e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
KHECPKLA_01939 4.39e-209 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
KHECPKLA_01940 6.53e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KHECPKLA_01941 1.41e-20 - - - M - - - Rib/alpha-like repeat
KHECPKLA_01942 0.0 - - - M - - - Rib/alpha-like repeat
KHECPKLA_01943 1.26e-198 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
KHECPKLA_01944 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
KHECPKLA_01945 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
KHECPKLA_01946 6.24e-197 - - - EG - - - EamA-like transporter family
KHECPKLA_01947 1.16e-24 - - - S - - - PFAM Archaeal ATPase
KHECPKLA_01948 2.13e-22 - - - S - - - PFAM Archaeal ATPase
KHECPKLA_01949 1.64e-50 - - - S - - - PFAM Archaeal ATPase
KHECPKLA_01950 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
KHECPKLA_01952 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
KHECPKLA_01953 3.31e-73 - - - - - - - -
KHECPKLA_01954 5.44e-124 - - - M - - - LPXTG-motif cell wall anchor domain protein
KHECPKLA_01955 3.21e-62 - - - K - - - Helix-turn-helix domain
KHECPKLA_01956 1.53e-184 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
KHECPKLA_01957 1.35e-93 - - - L - - - nuclease
KHECPKLA_01958 1.57e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
KHECPKLA_01959 4.17e-238 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KHECPKLA_01960 2.57e-126 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
KHECPKLA_01961 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KHECPKLA_01962 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
KHECPKLA_01963 3.84e-211 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
KHECPKLA_01964 0.0 - - - S - - - Putative threonine/serine exporter
KHECPKLA_01965 4.67e-237 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
KHECPKLA_01966 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
KHECPKLA_01967 0.0 - - - S - - - Bacterial membrane protein, YfhO
KHECPKLA_01968 2.31e-111 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KHECPKLA_01969 7.26e-215 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
KHECPKLA_01970 2.32e-86 - - - - - - - -
KHECPKLA_01971 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KHECPKLA_01972 1.54e-91 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KHECPKLA_01973 2.37e-309 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
KHECPKLA_01974 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KHECPKLA_01975 5.66e-277 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
KHECPKLA_01976 1.09e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
KHECPKLA_01977 5.43e-179 - - - E - - - GDSL-like Lipase/Acylhydrolase family
KHECPKLA_01978 1.71e-127 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KHECPKLA_01979 1.71e-206 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
KHECPKLA_01980 3.84e-200 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KHECPKLA_01981 8.33e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
KHECPKLA_01982 8.97e-76 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
KHECPKLA_01983 1.67e-222 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
KHECPKLA_01984 2.94e-124 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KHECPKLA_01985 1.31e-213 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KHECPKLA_01986 9.74e-176 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
KHECPKLA_01987 3.68e-228 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
KHECPKLA_01988 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
KHECPKLA_01989 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KHECPKLA_01990 2.29e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KHECPKLA_01991 1.13e-145 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
KHECPKLA_01992 4.62e-132 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
KHECPKLA_01993 6.5e-163 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_01994 2.35e-186 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
KHECPKLA_01995 1.77e-137 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
KHECPKLA_01996 7.18e-190 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KHECPKLA_01997 1.36e-308 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
KHECPKLA_01998 1.26e-93 - - - S - - - Phage integrase family
KHECPKLA_02003 1.07e-29 - - - S - - - sequence-specific DNA binding
KHECPKLA_02007 9.78e-77 - - - L - - - Belongs to the 'phage' integrase family
KHECPKLA_02008 2.25e-104 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
KHECPKLA_02010 3.59e-39 - - - S - - - ORF6C domain
KHECPKLA_02012 1.45e-22 - - - - - - - -
KHECPKLA_02013 3.47e-40 - - - - - - - -
KHECPKLA_02014 4.11e-25 - - - - - - - -
KHECPKLA_02019 1.02e-84 - - - S - - - AAA domain
KHECPKLA_02022 2.85e-210 - - - S - - - helicase activity
KHECPKLA_02025 1.67e-35 - - - S - - - Protein of unknown function (DUF669)
KHECPKLA_02027 2.59e-316 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
KHECPKLA_02028 1.79e-15 - - - K - - - transcriptional
KHECPKLA_02042 8.44e-54 - - - S - - - VRR_NUC
KHECPKLA_02044 5.77e-28 - - - S - - - Phage transcriptional regulator, ArpU family
KHECPKLA_02045 2.48e-32 - - - - - - - -
KHECPKLA_02046 6.43e-157 xtmA - - L ko:K07474 - ko00000 Terminase small subunit
KHECPKLA_02047 5.1e-302 - - - S - - - Terminase-like family
KHECPKLA_02048 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
KHECPKLA_02049 1.67e-52 - - - S - - - Cysteine protease Prp
KHECPKLA_02050 2.56e-249 - - - S - - - Phage Mu protein F like protein
KHECPKLA_02051 2.92e-125 - - - S - - - Domain of unknown function (DUF4355)
KHECPKLA_02052 1.17e-66 - - - - - - - -
KHECPKLA_02053 8.24e-229 - - - S - - - Phage major capsid protein E
KHECPKLA_02054 8.77e-51 - - - - - - - -
KHECPKLA_02055 4.85e-68 - - - - - - - -
KHECPKLA_02056 5.94e-107 - - - - - - - -
KHECPKLA_02057 2.18e-71 - - - - - - - -
KHECPKLA_02058 6.25e-92 - - - S - - - Phage tail tube protein, TTP
KHECPKLA_02059 2.24e-80 - - - - - - - -
KHECPKLA_02060 3.48e-49 - - - - - - - -
KHECPKLA_02061 0.0 - - - L - - - Phage tail tape measure protein TP901
KHECPKLA_02062 3.15e-78 - - - - - - - -
KHECPKLA_02063 0.0 - - - LM - - - gp58-like protein
KHECPKLA_02065 2.86e-48 - - - - - - - -
KHECPKLA_02069 1.54e-174 - - - M - - - Glycosyl hydrolases family 25
KHECPKLA_02070 4.24e-78 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
KHECPKLA_02071 2.22e-155 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
KHECPKLA_02072 4.77e-164 - - - - - - - -
KHECPKLA_02073 1.79e-146 - - - - - - - -
KHECPKLA_02074 1.45e-30 - - - - - - - -
KHECPKLA_02075 2.88e-129 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
KHECPKLA_02076 2.26e-164 - - - - - - - -
KHECPKLA_02077 9.09e-214 - - - - - - - -
KHECPKLA_02078 8.89e-293 rsmF - - J - - - NOL1 NOP2 sun family protein
KHECPKLA_02079 9.83e-66 ybjQ - - S - - - Belongs to the UPF0145 family
KHECPKLA_02080 3.08e-209 - - - S - - - DUF218 domain
KHECPKLA_02081 1.82e-187 yxeH - - S - - - hydrolase
KHECPKLA_02082 0.0 - - - I - - - Protein of unknown function (DUF2974)
KHECPKLA_02083 2.62e-152 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KHECPKLA_02084 4.82e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KHECPKLA_02085 5.91e-211 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KHECPKLA_02086 9.72e-121 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHECPKLA_02087 2.31e-220 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
KHECPKLA_02088 2.15e-299 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KHECPKLA_02089 5.11e-266 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
KHECPKLA_02090 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
KHECPKLA_02091 9.76e-120 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KHECPKLA_02092 3.83e-132 pncA - - Q - - - Isochorismatase family
KHECPKLA_02093 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KHECPKLA_02094 1.57e-218 - - - M - - - Glycosyl transferases group 1
KHECPKLA_02095 3.13e-137 alkD - - L - - - DNA alkylation repair enzyme
KHECPKLA_02096 9.19e-155 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
KHECPKLA_02097 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)